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Justin E Jones

Affiliations: 
University of South Carolina, Columbia, SC 
Area:
Biochemistry, Chemistry
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"Justin Jones"
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Paul R. Thompson grad student University of South Carolina

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Dreyton CJ, Knuckley B, Jones JE, et al. (2014) Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism. Biochemistry. 53: 4426-33
Foyn H, Jones JE, Lewallen D, et al. (2013) Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors. Acs Chemical Biology. 8: 1121-7
Jones JE, Slack JL, Fang P, et al. (2012) Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. Acs Chemical Biology. 7: 160-5
Causey CP, Jones JE, Slack JL, et al. (2011) The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors. Journal of Medicinal Chemistry. 54: 6919-35
Obianyo O, Causey CP, Jones JE, et al. (2011) Activity-based protein profiling of protein arginine methyltransferase 1. Acs Chemical Biology. 6: 1127-35
Chumanevich AA, Causey CP, Knuckley BA, et al. (2011) Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G929-38
Jones JE, Dreyton CJ, Flick H, et al. (2010) Mechanistic studies of agmatine deiminase from multiple bacterial species. Biochemistry. 49: 9413-23
Knuckley B, Jones JE, Bachovchin DA, et al. (2010) A fluopol-ABPP HTS assay to identify PAD inhibitors. Chemical Communications (Cambridge, England). 46: 7175-7
Obianyo O, Causey CP, Osborne TC, et al. (2010) A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation. Chembiochem : a European Journal of Chemical Biology. 11: 1219-23
Knuckley B, Causey CP, Jones JE, et al. (2010) Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3. Biochemistry. 49: 4852-63
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