Andrew Nguyen
Affiliations: | University of St Louis, St. Louis, MO, United States |
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"Andrew Nguyen"Parents
Sign in to add mentor| Russel DeBose-Boyd | grad student | UTSW | |
| Robert Farese | post-doc | ||
| Tobias c Walther | post-doc | University of St Louis |
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Publications
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| Boland S, Swarup S, Ambaw YA, et al. (2022) Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis. Nature Communications. 13: 5924 |
| Nguyen AD, Nguyen TA, Singh RK, et al. (2018) Progranulin in the hematopoietic compartment protects mice from atherosclerosis. Atherosclerosis. 277: 145-154 |
| Nguyen AD, Nguyen TA, Zhang J, et al. (2018) Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America |
| Hwang S, Nguyen AD, Jo Y, et al. (2017) Hypoxia-inducible factor-1α activates insig-2 transcription for degradation of HMG CoA reductase in the liver. The Journal of Biological Chemistry |
| Nguyen AD, Nguyen TA, Martens LH, et al. (2013) Progranulin: at the interface of neurodegenerative and metabolic diseases. Trends in Endocrinology and Metabolism: Tem. 24: 597-606 |
| Faulkner RA, Nguyen AD, Jo Y, et al. (2013) Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells. Journal of Lipid Research. 54: 1011-22 |
| Nguyen AD, Nguyen TA, Cenik B, et al. (2013) Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL). The Journal of Biological Chemistry. 288: 8627-35 |
| Nguyen AD, Lee SH, DeBose-Boyd RA. (2009) Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells. The Journal of Biological Chemistry. 284: 26778-88 |
| Nguyen AD, McDonald JG, Bruick RK, et al. (2007) Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs. The Journal of Biological Chemistry. 282: 27436-46 |
| Lee PC, Nguyen AD, Debose-Boyd RA. (2007) Mutations within the membrane domain of HMG-CoA reductase confer resistance to sterol-accelerated degradation. Journal of Lipid Research. 48: 318-27 |