Hilda A. Namanja, Ph.D. - Publications
Affiliations: | 2012 | Chemistry | Purdue University, West Lafayette, IN, United States |
Area:
Chemical BiologyYear | Citation | Score | |||
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2014 | Emmert D, Campos CR, Ward D, Lu P, Namanja HA, Bohn K, Miller DS, Sharom FJ, Chmielewski J, Hrycyna CA. Reversible dimers of the atypical antipsychotic quetiapine inhibit p-glycoprotein-mediated efflux in vitro with increased binding affinity and in situ at the blood-brain barrier. Acs Chemical Neuroscience. 5: 305-17. PMID 24483607 DOI: 10.1021/Cn4002329 | 0.709 | |||
2014 | Hrycyna CA, Summers RL, Lehane AM, Pires MM, Namanja H, Bohn K, Kuriakose J, Ferdig M, Henrich PP, Fidock DA, Kirk K, Chmielewski J, Martin RE. Quinine dimers are potent inhibitors of the Plasmodium falciparum chloroquine resistance transporter and are active against quinoline-resistant P. falciparum. Acs Chemical Biology. 9: 722-30. PMID 24369685 DOI: 10.1021/Cb4008953 | 0.507 | |||
2013 | Namanja HA, Emmert D, Hrycyna CA, Chmielewski J. Homodimers of the Antiviral Abacavir as Modulators of P-glycoprotein Transport in Cell Culture: Probing Tether Length. Medchemcomm. 4. PMID 24273637 DOI: 10.1039/C3Md00196B | 0.704 | |||
2012 | Namanja HA, Emmert D, Davis DA, Campos C, Miller DS, Hrycyna CA, Chmielewski J. Toward eradicating HIV reservoirs in the brain: inhibiting P-glycoprotein at the blood-brain barrier with prodrug abacavir dimers. Journal of the American Chemical Society. 134: 2976-80. PMID 21866921 DOI: 10.1021/Ja206867T | 0.656 | |||
2009 | Namanja HA, Emmert D, Pires MM, Hrycyna CA, Chmielewski J. Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer. Biochemical and Biophysical Research Communications. 388: 672-6. PMID 19683513 DOI: 10.1016/J.Bbrc.2009.08.056 | 0.639 | |||
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