| Year |
Citation |
Score |
| 2023 |
Agrahari A, Lipton M, Chmielewski J. Metal-Promoted Higher-Order Assembly of Disulfide-Stapled Helical Barrels. Nanomaterials (Basel, Switzerland). 13. PMID 37836285 DOI: 10.3390/nano13192645 |
0.759 |
|
| 2023 |
Ernenwein D, Geisler I, Pavlishchuk A, Chmielewski J. Metal-Assembled Collagen Peptide Microflorettes as Magnetic Resonance Imaging Agents. Molecules (Basel, Switzerland). 28. PMID 37049716 DOI: 10.3390/molecules28072953 |
0.803 |
|
| 2022 |
Jorgensen MD, Chmielewski J. Co-assembled Coiled-Coil Peptide Nanotubes with Enhanced Stability and Metal-Dependent Cargo Loading. Acs Omega. 7: 20945-20951. PMID 35755377 DOI: 10.1021/acsomega.2c01669 |
0.302 |
|
| 2021 |
Gleaton J, Curtis RW, Chmielewski J. Formation of Microcages from a Collagen Mimetic Peptide via Metal-Ligand Interactions. Molecules (Basel, Switzerland). 26. PMID 34443477 DOI: 10.3390/molecules26164888 |
0.802 |
|
| 2020 |
DeMarco AG, Milholland KL, Pendleton AL, Whitney JJ, Zhu P, Wesenberg DT, Nambiar M, Pepe A, Paula S, Chmielewski J, Wisecaver JH, Tao WA, Hall MC. Conservation of Cdc14 phosphatase specificity in plant fungal pathogens: implications for antifungal development. Scientific Reports. 10: 12073. PMID 32694511 DOI: 10.1038/S41598-020-68921-3 |
0.715 |
|
| 2020 |
Dietsche TA, Eldesouky HE, Zeiders SM, Seleem MN, Chmielewski J. Targeting Intracellular Pathogenic Bacteria Through N-Terminal Modification of Cationic Amphiphilic Polyproline Helices. The Journal of Organic Chemistry. 85: 7468-7475. PMID 32425046 DOI: 10.1021/Acs.Joc.0C00871 |
0.335 |
|
| 2020 |
Puvar K, Saleh AM, Curtis R, Zhou Y, Nyalapatla PR, Fu J, Rovira AR, Tor Y, Luo ZQ, Ghosh AK, Wirth MJ, Chmielewski J, Kinzer-Ursem TL, Das C. Fluorescent Probes for Monitoring Serine Ubiquitination. Biochemistry. PMID 32207972 DOI: 10.1021/Acs.Biochem.0C00067 |
0.574 |
|
| 2020 |
Ernenwein D, John SES, Stewart AJ, Morimoto BH, Chmielewski J, Lipton MA. Structural studies and cyclization of the neuroprotective octapeptide NAPVSIPQ to improve cell permeability Biopolymers. 112. DOI: 10.1002/Pep2.24179 |
0.77 |
|
| 2019 |
Nambiar M, Nepal M, Chmielewski J. Self-Assembling Coiled-Coil Peptide Nanotubes with Biomolecular Cargo Encapsulation. Acs Biomaterials Science & Engineering. 5: 5082-5087. PMID 33455255 DOI: 10.1021/Acsbiomaterials.9B01304 |
0.808 |
|
| 2019 |
Agrawal N, Rowe J, Lan J, Yu Q, Hrycyna CA, Chmielewski J. Potential tools for eradicating HIV reservoirs in the brain: the development of Trojan horse prodrugs for the inhibition of P-glycoprotein with anti-HIV-1 activity. Journal of Medicinal Chemistry. PMID 31505928 DOI: 10.1021/Acs.Jmedchem.9B00779 |
0.745 |
|
| 2018 |
Brezden A, Mohamed MF, Nepal M, Harwood JS, Kuriakose J, Seleem MN, Chmielewski J. Correction to "Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial Cell-Penetrating Peptide". Journal of the American Chemical Society. PMID 30264564 DOI: 10.1021/jacs.8b09906 |
0.817 |
|
| 2018 |
Nambiar M, Wang LS, Rotello VM, Chmielewski J. Reversible hierarchical assembly of trimeric coiled-coil peptides into banded nano- and micro-structures. Journal of the American Chemical Society. PMID 30222333 DOI: 10.1021/Jacs.8B08163 |
0.778 |
|
| 2018 |
Nepal M, Mohamed M, Blade R, Eldesouky H, Anderson T, Seleem MN, Chmielewski J. A Library Approach to Cationic Amphiphilic Polyproline Helices that Target Intracellular Pathogenic Bacteria. Acs Infectious Diseases. PMID 29979033 DOI: 10.1021/Acsinfecdis.8B00124 |
0.767 |
|
| 2017 |
Mohamed MF, Brezden A, Mohammad H, Chmielewski J, Seleem MN. A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. Scientific Reports. 7: 6953. PMID 28761101 DOI: 10.1038/S41598-017-07440-0 |
0.809 |
|
| 2017 |
Namanja-Magliano HA, Bohn K, Agrawal N, Willoughby ME, Hrycyna CA, Chmielewski J. Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine. Bioorganic & Medicinal Chemistry. PMID 28712845 DOI: 10.1016/J.Bmc.2017.07.001 |
0.57 |
|
| 2017 |
Bohn K, Lange A, Chmielewski J, Hrycyna CA. Dual Modulation of Human P-glycoprotein and ABCG2 with Prodrug Dimers of the Atypical Antipsychotic Agent Paliperidone in a Model of the Blood-Brain Barrier. Molecular Pharmaceutics. PMID 28264565 DOI: 10.1021/Acs.Molpharmaceut.6B01044 |
0.319 |
|
| 2017 |
Mohamed MF, Brezden A, Mohammad H, Chmielewski J, Seleem MN. Targeting biofilms and persisters of ESKAPE pathogens with P14KanS, a kanamycin peptide conjugate. Biochimica Et Biophysica Acta. 1861: 848-859. PMID 28132897 DOI: 10.1016/J.Bbagen.2017.01.029 |
0.817 |
|
| 2017 |
Strauss K, Chmielewski J. Advances in the design and higher-order assembly of collagen mimetic peptides for regenerative medicine. Current Opinion in Biotechnology. 46: 34-41. PMID 28126669 DOI: 10.1016/J.Copbio.2016.10.013 |
0.674 |
|
| 2016 |
Strauss K, Chmielewski J. Metal-Promoted Assembly of Two Collagen Mimetic Peptides into a Biofunctional "Spiraled Horn" Scaffold. Materials (Basel, Switzerland). 9. PMID 28773959 DOI: 10.3390/Ma9100838 |
0.696 |
|
| 2016 |
Nepal M, Sheedlo MJ, Das C, Chmielewski J. Accessing Three-Dimensional Crystals with Incorporated Guests through Metal-Directed Coiled-Coil Peptide Assembly. Journal of the American Chemical Society. PMID 27500907 DOI: 10.1021/Jacs.6B06708 |
0.806 |
|
| 2016 |
Brezden A, Mohamed MF, Nepal M, Harwood JS, Kuriakose J, Seleem MN, Chmielewski J. Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial, Cell Penetrating Peptide. Journal of the American Chemical Society. PMID 27494027 DOI: 10.1021/Jacs.6B04831 |
0.802 |
|
| 2015 |
Gleaton J, Chmielewski J. Thermally Controlled Collagen Peptide Cages for Biopolymer Delivery. Acs Biomaterials Science & Engineering. 1: 1002-1008. PMID 33429531 DOI: 10.1021/Acsbiomaterials.5B00241 |
0.828 |
|
| 2015 |
Thangamani S, Nepal M, Chmielewski J, Seleem MN. Antibacterial activity and therapeutic efficacy of Fl-P(R)P(R)P(L)-5, a cationic amphiphilic polyproline helix, in a mouse model of staphylococcal skin infection. Drug Design, Development and Therapy. 9: 5749-54. PMID 26543355 DOI: 10.2147/Dddt.S94505 |
0.754 |
|
| 2015 |
Kotha RR, Chmielewski J. Controlling the morphology of metal-triggered collagen peptide assemblies through ligand alteration. Biopolymers. 104: 379-83. PMID 26031615 DOI: 10.1002/Bip.22690 |
0.449 |
|
| 2015 |
Nepal M, Thangamani S, Seleem MN, Chmielewski J. Targeting intracellular bacteria with an extended cationic amphiphilic polyproline helix. Organic & Biomolecular Chemistry. 13: 5930-6. PMID 25925008 DOI: 10.1039/C5Ob00227C |
0.772 |
|
| 2015 |
Thangamani S, Nepal M, Chmielewski J, Seleem MN. Antibacterial activity and therapeutic efficacy of Fl-PRPRPL-5, a cationic amphiphilic polyproline helix, in a mouse model of staphylococcal skin infection Drug Design, Development and Therapy. 9: 5749-5754. DOI: 10.2147/DDDT.S94505 |
0.742 |
|
| 2015 |
Nepal M, Thangamani S, Seleem MN, Chmielewski J. Targeting intracellular bacteria with an extended cationic amphiphilic polyproline helix Organic and Biomolecular Chemistry. 13: 5930-5936. DOI: 10.1039/c5ob00227c |
0.759 |
|
| 2014 |
Hernandez-Gordillo V, Chmielewski J. Mimicking the extracellular matrix with functionalized, metal-assembled collagen peptide scaffolds. Biomaterials. 35: 7363-73. PMID 24933513 DOI: 10.1016/J.Biomaterials.2014.05.019 |
0.373 |
|
| 2014 |
Rubert Pérez CM, Rank LA, Chmielewski J. Tuning the thermosensitive properties of hybrid collagen peptide-polymer hydrogels. Chemical Communications (Cambridge, England). 50: 8174-6. PMID 24926620 DOI: 10.1039/C4Cc03171G |
0.821 |
|
| 2014 |
Emmert D, Campos CR, Ward D, Lu P, Namanja HA, Bohn K, Miller DS, Sharom FJ, Chmielewski J, Hrycyna CA. Reversible dimers of the atypical antipsychotic quetiapine inhibit p-glycoprotein-mediated efflux in vitro with increased binding affinity and in situ at the blood-brain barrier. Acs Chemical Neuroscience. 5: 305-17. PMID 24483607 DOI: 10.1021/Cn4002329 |
0.776 |
|
| 2014 |
Hrycyna CA, Summers RL, Lehane AM, Pires MM, Namanja H, Bohn K, Kuriakose J, Ferdig M, Henrich PP, Fidock DA, Kirk K, Chmielewski J, Martin RE. Quinine dimers are potent inhibitors of the Plasmodium falciparum chloroquine resistance transporter and are active against quinoline-resistant P. falciparum. Acs Chemical Biology. 9: 722-30. PMID 24369685 DOI: 10.1021/Cb4008953 |
0.763 |
|
| 2014 |
Hernandez-Gordillo V, Geisler I, Chmielewski J. Dimeric unnatural polyproline-rich peptides with enhanced antibacterial activity. Bioorganic & Medicinal Chemistry Letters. 24: 556-9. PMID 24365160 DOI: 10.1016/J.Bmcl.2013.12.023 |
0.833 |
|
| 2013 |
Namanja HA, Emmert D, Hrycyna CA, Chmielewski J. Homodimers of the Antiviral Abacavir as Modulators of P-glycoprotein Transport in Cell Culture: Probing Tether Length. Medchemcomm. 4. PMID 24273637 DOI: 10.1039/C3Md00196B |
0.779 |
|
| 2013 |
Kuriakose J, Hernandez-Gordillo V, Nepal M, Brezden A, Pozzi V, Seleem MN, Chmielewski J. Targeting intracellular pathogenic bacteria with unnatural proline-rich peptides: coupling antibacterial activity with macrophage penetration. Angewandte Chemie (International Ed. in English). 52: 9664-7. PMID 23960012 DOI: 10.1002/Anie.201302693 |
0.807 |
|
| 2013 |
Przybyla DE, Rubert Pérez CM, Gleaton J, Nandwana V, Chmielewski J. Hierarchical assembly of collagen peptide triple helices into curved disks and metal ion-promoted hollow spheres. Journal of the American Chemical Society. 135: 3418-22. PMID 23402552 DOI: 10.1021/Ja307651E |
0.796 |
|
| 2013 |
Zhao L, Chmielewski J. Inhibition of HIV-1 integrase dimerization and activity with crosslinked interfacial peptides Bioorganic and Medicinal Chemistry. 21: 4041-4044. PMID 23165001 DOI: 10.1016/J.Bmc.2012.10.032 |
0.496 |
|
| 2012 |
Chmielewski J, Hrycyna C. Research spotlight: Tools for eradicating HIV in the brain: Prodrug dimeric inhibitors of P-gp Therapeutic Delivery. 3: 689-692. PMID 22838065 DOI: 10.4155/Tde.12.49 |
0.321 |
|
| 2012 |
Kuriakose J, Hrycyna CA, Chmielewski J. Click chemistry-derived bivalent quinine inhibitors of P-glycoprotein-mediated cellular efflux. Bioorganic & Medicinal Chemistry Letters. 22: 4410-2. PMID 22632934 DOI: 10.1016/J.Bmcl.2012.04.125 |
0.647 |
|
| 2012 |
Pires MM, Lee J, Ernenwein D, Chmielewski J. Controlling the morphology of metal-promoted higher ordered assemblies of collagen peptides with varied core lengths. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 1993-7. PMID 22165843 DOI: 10.1021/La203848R |
0.826 |
|
| 2012 |
Rubert Pérez C, López-Pérez D, Chmielewski J, Lipton M. Small Molecule Inhibitors of Anthrax Toxin-induced Cytotoxicity Targeted Against Protective Antigen Chemical Biology and Drug Design. 79: 260-269. PMID 22146079 DOI: 10.1111/J.1747-0285.2011.01285.X |
0.321 |
|
| 2012 |
Kalafut D, Anderson TN, Chmielewski J. Mitochondrial targeting of a cationic amphiphilic polyproline helix Bioorganic and Medicinal Chemistry Letters. 22: 561-563. PMID 22130131 DOI: 10.1016/J.Bmcl.2011.10.077 |
0.385 |
|
| 2012 |
Namanja HA, Emmert D, Davis DA, Campos C, Miller DS, Hrycyna CA, Chmielewski J. Toward eradicating HIV reservoirs in the brain: inhibiting P-glycoprotein at the blood-brain barrier with prodrug abacavir dimers. Journal of the American Chemical Society. 134: 2976-80. PMID 21866921 DOI: 10.1021/Ja206867T |
0.778 |
|
| 2011 |
Pires MM, Przybyla DE, Rubert Pérez CM, Chmielewski J. Metal-mediated tandem coassembly of collagen peptides into banded microstructures. Journal of the American Chemical Society. 133: 14469-71. PMID 21863857 DOI: 10.1021/Ja2042645 |
0.791 |
|
| 2011 |
Pérez CM, Panitch A, Chmielewski J. A collagen peptide-based physical hydrogel for cell encapsulation. Macromolecular Bioscience. 11: 1426-31. PMID 21830301 DOI: 10.1002/Mabi.201100230 |
0.393 |
|
| 2011 |
Geisler IM, Chmielewski J. Dimeric cationic amphiphilic polyproline helices for mitochondrial targeting. Pharmaceutical Research. 28: 2797-807. PMID 21647789 DOI: 10.1007/S11095-011-0493-7 |
0.803 |
|
| 2011 |
Pires MM, Ernenwein D, Chmielewski J. Selective decoration and release of his-tagged proteins from metal-assembled collagen peptide microflorettes Biomacromolecules. 12: 2429-2433. PMID 21615181 DOI: 10.1021/Bm2004934 |
0.793 |
|
| 2010 |
Lee SG, Chmielewski J. Cross-linked peptoid-based dimerization inhibitors of HIV-1 protease. Chembiochem : a European Journal of Chemical Biology. 11: 1513-6. PMID 20575134 DOI: 10.1002/Cbic.201000248 |
0.632 |
|
| 2010 |
Przybyla DE, Chmielewski J. Metal-triggered collagen peptide disk formation. Journal of the American Chemical Society. 132: 7866-7. PMID 20499839 DOI: 10.1021/Ja103148T |
0.831 |
|
| 2010 |
Przybyla DE, Chmielewski J. Higher-order assembly of collagen peptides into nano- and microscale materials. Biochemistry. 49: 4411-9. PMID 20415447 DOI: 10.1021/Bi902129P |
0.831 |
|
| 2010 |
Lee J, Chmielewski J. Folding studies of pH-dependent collagen peptides. Chemical Biology & Drug Design. 75: 161-8. PMID 20028399 DOI: 10.1111/J.1747-0285.2009.00929.X |
0.474 |
|
| 2010 |
Li L, Geisler I, Chmielewski J, Cheng JX. Cationic amphiphilic polyproline helix P11LRR targets intracellular mitochondria. Journal of Controlled Release : Official Journal of the Controlled Release Society. 142: 259-66. PMID 19840824 DOI: 10.1016/J.Jconrel.2009.10.012 |
0.775 |
|
| 2010 |
Ernenwein D, Ghosh P, Rotello V, Chmielewski J. Gold nanoparticle self-assembly promoted by a non-covalent, charge-complemented coiled-coil peptide Journal of Materials Chemistry. 20: 5608-5611. DOI: 10.1039/C0Jm01108H |
0.803 |
|
| 2009 |
Pires MM, Przybyla DE, Chmielewski J. A metal-collagen peptide framework for three-dimensional cell culture. Angewandte Chemie (International Ed. in English). 48: 7813-7. PMID 19757466 DOI: 10.1002/Anie.200902375 |
0.81 |
|
| 2009 |
Chmielewski J. Protease dimer formation disrupted Nature Chemical Biology. 5: 607-608. PMID 19690531 DOI: 10.1038/Nchembio0909-607 |
0.308 |
|
| 2009 |
Namanja HA, Emmert D, Pires MM, Hrycyna CA, Chmielewski J. Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer. Biochemical and Biophysical Research Communications. 388: 672-6. PMID 19683513 DOI: 10.1016/J.Bbrc.2009.08.056 |
0.772 |
|
| 2009 |
Pires MM, Chmielewski J. Self-assembly of collagen peptides into microflorettes via metal coordination Journal of the American Chemical Society. 131: 2706-2712. PMID 19182901 DOI: 10.1021/Ja8088845 |
0.72 |
|
| 2009 |
Geisler I, Chmielewski J. Cationic amphiphilic polyproline helices: Side-chain variations and cell-specific internalization Chemical Biology and Drug Design. 73: 39-45. PMID 19152633 DOI: 10.1111/J.1747-0285.2008.00759.X |
0.823 |
|
| 2009 |
Davis DA, Tebbs IR, Daniels SI, Stahl SJ, Kaufman JD, Wingfield P, Bowman MJ, Chmielewski J, Yarchoan R. Analysis and characterization of dimerization inhibition of a multi-drug-resistant human immunodeficiency virus type 1 protease using a novel size-exclusion chromatographic approach. The Biochemical Journal. 419: 497-506. PMID 19149765 DOI: 10.1042/Bj20082068 |
0.363 |
|
| 2009 |
Pires MM, Emmert D, Hrycyna CA, Chmielewski J. Inhibition of P-glycoprotein-mediated paclitaxel resistance by reversibly linked quinine homodimers. Molecular Pharmacology. 75: 92-100. PMID 18945821 DOI: 10.1124/Mol.108.050492 |
0.646 |
|
| 2009 |
Bowman MJ, Chmielewski J. Sidechain-linked inhibitors of HIV-1 protease dimerization. Bioorganic & Medicinal Chemistry. 17: 967-76. PMID 18337105 DOI: 10.1016/J.Bmc.2008.02.060 |
0.334 |
|
| 2008 |
Lee SG, Lee JY, Chmielewski J. Investigation of pH-dependent collagen triple-helix formation. Angewandte Chemie (International Ed. in English). 47: 8429-32. PMID 18816568 DOI: 10.1002/Anie.200802224 |
0.503 |
|
| 2008 |
Przybyla DE, Chmielewski J. Metal-triggered radial self-assembly of collagen peptide fibers. Journal of the American Chemical Society. 130: 12610-1. PMID 18763780 DOI: 10.1021/Ja804942W |
0.804 |
|
| 2008 |
Zhu H, Coleman DM, Dehen CJ, Geisler IM, Zemlyanov D, Chmielewski J, Simpson GJ, Wei A. Assembly of dithiocarbamate-anchored monolayers on gold surfaces in aqueous solutions. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 8660-6. PMID 18616309 DOI: 10.1021/La801254B |
0.766 |
|
| 2008 |
Gaddis BD, Rubert Pérez CM, Chmielewski J. Inhibitors of anthrax lethal factor based upon N-oleoyldopamine. Bioorganic & Medicinal Chemistry Letters. 18: 2467-70. PMID 18314330 DOI: 10.1016/J.Bmcl.2008.02.044 |
0.753 |
|
| 2008 |
Pires MM, Chmielewski J. Fluorescence imaging of cellular glutathione using a latent rhodamine Organic Letters. 10: 837-840. PMID 18257581 DOI: 10.1021/Ol702769N |
0.632 |
|
| 2007 |
Gaddis BD, Avramova LV, Chmielewski J. Inhibitors of anthrax lethal factor. Bioorganic & Medicinal Chemistry Letters. 17: 4575-8. PMID 17574849 DOI: 10.1016/J.Bmcl.2007.05.089 |
0.768 |
|
| 2007 |
Hershberger SJ, Lee SG, Chmielewski J. Scaffolds for blocking protein-protein interactions. Current Topics in Medicinal Chemistry. 7: 928-42. PMID 17508924 DOI: 10.2174/156802607780906726 |
0.775 |
|
| 2007 |
Fillon Y, Verma A, Ghosh P, Ernenwein D, Rotello VM, Chmielewski J. Peptide ligation catalyzed by functionalized gold nanoparticles. Journal of the American Chemical Society. 129: 6676-7. PMID 17488077 DOI: 10.1021/Ja070301+ |
0.788 |
|
| 2007 |
Geisler I, Chmielewski J. Probing length effects and mechanism of cell penetrating agents mounted on a polyproline helix scaffold Bioorganic and Medicinal Chemistry Letters. 17: 2765-2768. PMID 17363245 DOI: 10.1016/J.Bmcl.2007.02.077 |
0.812 |
|
| 2006 |
Pires MM, Hrycyna CA, Chmielewski J. Bivalent probes of the human multidrug transporter P-glycoprotein. Biochemistry. 45: 11695-702. PMID 16981729 DOI: 10.1021/Bi0608109 |
0.641 |
|
| 2006 |
Lee SG, Chmielewski J. Rapid synthesis and in situ screening of potent HIV-1 protease dimerization inhibitors. Chemistry & Biology. 13: 421-6. PMID 16632254 DOI: 10.1016/J.Chembiol.2006.02.012 |
0.583 |
|
| 2006 |
Ulysse LG, Chmielewski J. A light-activated beta-turn scaffold within a somatostatin analog: NMR structure and biological activity. Chemical Biology & Drug Design. 67: 127-36. PMID 16492160 DOI: 10.1111/J.1747-0285.2005.00337.X |
0.8 |
|
| 2006 |
Ulysse LG, Chmielewski J. A light-activated β-turn scaffold within a somatostatin analog: NMR structure and biological activity Chemical Biology and Drug Design. 67: 127-136. DOI: 10.1111/j.1747-0285.2005.00337.x |
0.764 |
|
| 2005 |
Fillon YA, Anderson JP, Chmielewski J. Cell penetrating agents based on a polyproline helix scaffold. Journal of the American Chemical Society. 127: 11798-803. PMID 16104758 DOI: 10.1021/Ja052377G |
0.818 |
|
| 2005 |
Lee HM, Chmielewski J. Liposomal cargo unloading induced by pH-sensitive peptides Journal of Peptide Research. 65: 355-363. PMID 15787966 DOI: 10.1111/J.1399-3011.2005.00229.X |
0.378 |
|
| 2005 |
You SH, Chmielewski J. Development of low molecular weight HIV-1 protease dimerization inhibitors Journal of Medicinal Chemistry. 48: 2239-2242. PMID 15771466 DOI: 10.1021/Jm049581J |
0.345 |
|
| 2005 |
Zhao L, Chmielewski J. Inhibiting protein-protein interactions using designed molecules Current Opinion in Structural Biology. 15: 31-34. PMID 15718130 DOI: 10.1016/J.Sbi.2005.01.005 |
0.456 |
|
| 2004 |
Ghosh I, Chmielewski J. Peptide self-assembly as a model of proteins in the pre-genomic world. Current Opinion in Chemical Biology. 8: 640-4. PMID 15556409 DOI: 10.1016/J.Cbpa.2004.09.001 |
0.727 |
|
| 2004 |
Nayak S, Lee H, Chmielewski J, Lyon LA. Folate-mediated cell targeting and cytotoxicity using thermoresponsive microgels Journal of the American Chemical Society. 126: 10258-10259. PMID 15315434 DOI: 10.1021/Ja0474143 |
0.527 |
|
| 2004 |
Shultz MD, Ham YW, Lee SG, Davis DA, Brown C, Chmielewski J. Small-molecule dimerization inhibitors of wild-type and mutant HIV protease: a focused library approach. Journal of the American Chemical Society. 126: 9886-7. PMID 15303839 DOI: 10.1021/Ja048139N |
0.803 |
|
| 2004 |
Hwang YS, Chmielewski J. A unidirectional crosslinking strategy for HIV-1 protease dimerization inhibitors Bioorganic and Medicinal Chemistry Letters. 14: 4297-4300. PMID 15261290 DOI: 10.1016/J.Bmcl.2004.05.081 |
0.646 |
|
| 2004 |
Ragin AD, Chmielewski J. Probing essential residues for cellular uptake with a cationic nuclear localization signal sequence. The Journal of Peptide Research : Official Journal of the American Peptide Society. 63: 155-60. PMID 15009537 DOI: 10.1111/J.1399-3011.2003.00115.X |
0.79 |
|
| 2004 |
Bowman MJ, Chmielewski J. Crucial amides for dimerization inhibitors of HIV-1 protease. Bioorganic & Medicinal Chemistry Letters. 14: 1395-8. PMID 15006369 DOI: 10.1016/J.Bmcl.2003.09.099 |
0.344 |
|
| 2003 |
Li X, Chmielewski J. Peptide self-replication enhanced by a proline kink Journal of the American Chemical Society. 125: 11820-11821. PMID 14505395 DOI: 10.1021/Ja036569S |
0.452 |
|
| 2003 |
Li X, Chmielewski J. Challenges in the design of self replicating peptides Organic and Biomolecular Chemistry. 1: 901-904. PMID 12929626 DOI: 10.1039/B300738C |
0.434 |
|
| 2003 |
Zhao L, O'Reilly MK, Shultz MD, Chmielewski J. Interfacial peptide inhibitors of HIV-1 integrase activity and dimerization Bioorganic and Medicinal Chemistry Letters. 13: 1175-1177. PMID 12643937 DOI: 10.1016/S0960-894X(03)00040-4 |
0.749 |
|
| 2002 |
Bowman MJ, Chmielewski J. Novel strategies for targeting the dimerization interface of HIV protease with cross-linked interfacial peptides. Biopolymers. 66: 126-33. PMID 12325162 DOI: 10.1002/Bip.10232 |
0.4 |
|
| 2002 |
Ragin AD, Morgan RA, Chmielewski J. Cellular import mediated by nuclear localization signal Peptide sequences. Chemistry & Biology. 9: 943-8. PMID 12204694 DOI: 10.1016/S1074-5521(02)00189-8 |
0.832 |
|
| 2002 |
Issac R, Chmielewski J. Approaching exponential growth with a self-replicating peptide Journal of the American Chemical Society. 124: 6808-6809. PMID 12059185 DOI: 10.1021/Ja026024I |
0.816 |
|
| 2002 |
Turk MJ, Reddy JA, Chmielewski JA, Low PS. Characterization of a novel pH-sensitive peptide that enhances drug release from folate-targeted liposomes at endosomal pHs. Biochimica Et Biophysica Acta. 1559: 56-68. PMID 11825588 DOI: 10.1016/S0005-2736(01)00441-2 |
0.457 |
|
| 2001 |
Issac R, Ham YW, Chmielewski J. The design of self-replicating helical peptides. Current Opinion in Structural Biology. 11: 458-63. PMID 11495739 DOI: 10.1016/S0959-440X(00)00233-5 |
0.825 |
|
| 2001 |
Ghosh I, Bishop P, Chmielewski J. DNA binding properties of basic helix-loop-helix fusion proteins of Tal and E47 Journal of Peptide Research. 57: 354-360. PMID 11350595 DOI: 10.1034/J.1399-3011.2001.00846.X |
0.767 |
|
| 2000 |
Zutshi R, Chmielewski J. Targeting the dimerization interface for irreversible inhibition of HIV-1 protease Bioorganic and Medicinal Chemistry Letters. 10: 1901-1903. PMID 10987413 DOI: 10.1016/S0960-894X(00)00369-3 |
0.732 |
|
| 2000 |
Shultz MD, Bowman MJ, Ham YW, Zhao X, Tora G, Chmielewski J. Small-Molecule Inhibitors of HIV-1 Protease Dimerization Derived from Cross-Linked Interfacial Peptides This work was supported by NIH (GM52739) and NSF (9457372-CHE). Angewandte Chemie (International Ed. in English). 39: 2710-2713. PMID 10934401 DOI: 10.1002/1521-3773(20000804)39:15<2710::AID-ANIE2710>3.0.CO;2-P |
0.636 |
|
| 2000 |
Shultz M, Bowman M, Ham Y, Zhao X, Tora G, Chmielewski J. Small-Molecule Inhibitors of HIV-1 Protease Dimerization Derived from Cross-Linked Interfacial Peptides Angewandte Chemie. 112: 2822-2825. DOI: 10.1002/1521-3757(20000804)112:15<2822::Aid-Ange2822>3.0.Co;2-1 |
0.782 |
|
| 1999 |
Yao S, Chmielewski J. A pH-tunable peptide ligase Biopolymers - Peptide Science Section. 51: 370-375. PMID 10685048 DOI: 10.1002/(Sici)1097-0282(1999)51:5<370::Aid-Bip7>3.0.Co;2-T |
0.434 |
|
| 1999 |
Micklatcher C, Chmielewski J. Helical peptide and protein design Current Opinion in Chemical Biology. 3: 724-729. PMID 10600720 DOI: 10.1016/S1367-5931(99)00031-9 |
0.805 |
|
| 1999 |
Shultz MD, Chmielewski J. Probing the role of interfacial residues in a dimerization inhibitor of HIV-1 protease Bioorganic and Medicinal Chemistry Letters. 9: 2431-2436. PMID 10476882 DOI: 10.1016/S0960-894X(99)00400-X |
0.663 |
|
| 1999 |
Ghosh I, Issac R, Chmielewski J. Structure-function relationship in a β-sheet peptide Inhibitor of E47 dimerization and DNA binding Bioorganic and Medicinal Chemistry. 7: 61-66. PMID 10199656 DOI: 10.1016/S0968-0896(98)00214-4 |
0.809 |
|
| 1999 |
Yao S, Ghosh I, Zutshi R, Chmielewski J. A pH-Modulated, Self-Replicating Peptide [J. Am.Chem. Soc.1997,119, 10559−10560]. Journal of the American Chemical Society. 121: 8132-8132. DOI: 10.1021/Ja995525+ |
0.808 |
|
| 1998 |
Yao S, Ghosh I, Zutshi R, Chmielewski J. A Self-Replicating Peptide under Ionic Control. Angewandte Chemie (International Ed. in English). 37: 478-481. PMID 29711158 DOI: 10.1002/(Sici)1521-3773(19980302)37:4<478::Aid-Anie478>3.0.Co;2-V |
0.81 |
|
| 1998 |
Yao S, Brickner M, Pares-Matos EI, Chmielewski J. Uncoiling c-Jun coiled coils: inhibitory effects of truncated Fos peptides on Jun dimerization and DNA binding in vitro. Biopolymers. 47: 277-83. PMID 10036969 DOI: 10.1002/(Sici)1097-0282(1998)47:4<277::Aid-Bip3>3.0.Co;2-A |
0.736 |
|
| 1998 |
Ulysse LG, Chmielewski J. Restricting the flexibility of crosslinked, interfacial peptide inhibitors of HIV-1 protease Bioorganic and Medicinal Chemistry Letters. 8: 3281-3286. PMID 9873718 DOI: 10.1016/S0960-894X(98)00595-2 |
0.811 |
|
| 1998 |
Yao S, Zutshi R, Chmielewski J. Endothiopeptide inhibitors of HIV-1 protease Bioorganic and Medicinal Chemistry Letters. 8: 699-704. PMID 9871586 DOI: 10.1016/S0960-894X(98)00100-0 |
0.733 |
|
| 1998 |
Yao S, Ghosh I, Zutshi R, Chmielewski J. Selective amplification by auto- and cross-catalysis in a replicating peptide system Nature. 396: 447-450. PMID 9853750 DOI: 10.1038/24814 |
0.826 |
|
| 1998 |
Ghosh I, Chmielewski J. A β-sheet peptide inhibitor of E47 dimerization and DNA binding Chemistry and Biology. 5: 439-445. PMID 9710566 DOI: 10.1016/S1074-5521(98)90160-0 |
0.696 |
|
| 1998 |
Zutshi R, Brickner M, Chmielewski J. Inhibiting the assembly of protein-protein interfaces Current Opinion in Chemical Biology. 2: 62-66. PMID 9667909 DOI: 10.1016/S1367-5931(98)80036-7 |
0.797 |
|
| 1998 |
Brickner M, Chmielewski J. Inhibiting the dimeric restriction endonuclease EcoRI using interfacial helical peptides Chemistry and Biology. 5: 339-343. PMID 9653552 DOI: 10.1016/S1074-5521(98)90172-7 |
0.757 |
|
| 1998 |
Zutshi R, Shultz MD, Ulysse L, Lutgring R, Bishop P, Schweitzer B, Vogel K, Franciskovich J, Wilson M, Chmielewski J. Inhibiting the dimerization of HIV-1 protease Synlett. 1040-1044. DOI: 10.1055/S-1998-1854 |
0.754 |
|
| 1998 |
Yao S, Ghosh I, Zutshi R, Chmielewski J. Selbstreplikation eines Peptids unter Ionenkontrolle Angewandte Chemie. 110: 489-492. DOI: 10.1002/(Sici)1521-3757(19980216)110:4<489::Aid-Ange489>3.0.Co;2-K |
0.828 |
|
| 1998 |
Yao S, Ghosh I, Zutshi R, Chmielewski J. A self-replicating peptide under ionic control Angewandte Chemie - International Edition in English. 37: 478-481. |
0.692 |
|
| 1997 |
Chmielewski J, Lewis JJ, Lovell S, Zutshi R, Savickas P, Mitchell CA, Subramony JA, Kahr B. Single-crystal matrix isolation of biopolymers Journal of the American Chemical Society. 119: 10565-10566. DOI: 10.1021/Ja971370Z |
0.693 |
|
| 1997 |
Yao S, Ghosh I, Zutshi R, Chmielewski J. A pH-modulated, self-replicating peptide Journal of the American Chemical Society. 119: 10559-10560. DOI: 10.1021/Ja9710619 |
0.814 |
|
| 1997 |
Zutshi R, Franciskovich J, Shultz M, Schweitzer B, Bishop P, Wilson M, Chmielewski J. Targeting the dimerization interface of HIV-1 protease: Inhibition with cross-linked interfacial peptides Journal of the American Chemical Society. 119: 4841-4845. DOI: 10.1021/Ja962496J |
0.805 |
|
| 1997 |
Shultz MD, Chmielewski J. Hydrophobicity versus activity in crosslinked interfacial peptide inhibitors of HIV-1 protease Tetrahedron Asymmetry. 8: 3881-3886. DOI: 10.1016/S0957-4166(97)00572-7 |
0.682 |
|
| 1996 |
Lutgring R, Lipton M, Chmielewski J. Differential self assembly of amphiphilic helical peptides. Amino Acids. 10: 295-304. PMID 24178591 DOI: 10.1007/Bf00805858 |
0.837 |
|
| 1996 |
Vogel K, Cook J, Chmielewski J. Subtilisin-catalyzed religation of proteolyzed hen egg-white lysozyme: investigation of the role of disulfides. Chemistry & Biology. 3: 295-9. PMID 8807857 DOI: 10.1016/S1074-5521(96)90109-X |
0.325 |
|
| 1996 |
Vogel K, Wang S, Lee RJ, Chmielewski J, Low PS. Peptide-mediated release of folate-targeted liposome contents from endosomal compartments Journal of the American Chemical Society. 118: 1581-1586. DOI: 10.1021/Ja952725M |
0.413 |
|
| 1996 |
Lutgring R, Lipton M, Chmielewski J. Differential self assembly of amphiphilic helical peptides Amino Acids. 10: 295-304. DOI: 10.1007/BF00805858 |
0.821 |
|
| 1995 |
Bishop P, Jones C, Ghosh I, Chmielewski J. Synthesis of the basic-helix-loop-helix region of the immunoglobulin enhancer binding protein E47 and evaluation of its structural and DNA binding properties International Journal of Peptide and Protein Research. 46: 149-154. PMID 8567169 DOI: 10.1111/J.1399-3011.1995.Tb01330.X |
0.783 |
|
| 1995 |
Ulysse L, Cubillos J, Chmielewski J. Photoregulation of cyclic peptide conformation Journal of the American Chemical Society. 117: 8466-8467. DOI: 10.1021/Ja00137A023 |
0.829 |
|
| 1995 |
Bishop P, Ghosh I, Jones C, Chmielewski J. Basic-helix-loop-helix region of tal: Evaluation of structure and DNA affinity Journal of the American Chemical Society. 117: 8283-8284. DOI: 10.1021/Ja00136A032 |
0.762 |
|
| 1994 |
Chmielewski J, Lipton M. The rational design of highly stable, amphiphilic helical peptides International Journal of Peptide and Protein Research. 44: 152-157. PMID 7982759 DOI: 10.1111/J.1399-3011.1994.Tb00570.X |
0.318 |
|
| 1994 |
Lutgring R, Chmielewski J. General strategy for covalently stabilizing helical bundles: A novel five-helix bundle protein Journal of the American Chemical Society. 116: 6451-6452. DOI: 10.1021/Ja00093A062 |
0.777 |
|
| 1994 |
Ulysse L, Chmielewski J. The synthesis of a light-switchable amino acid for inclusion into conformationally mobile peptides Bioorganic & Medicinal Chemistry Letters. 4: 2145-2146. DOI: 10.1016/S0960-894X(01)80118-9 |
0.806 |
|
| 1993 |
Mihara H, Chmielewski JA, Kaiser ET. Synthesis of the 60 amino acid homeo domain and smaller fragments of the Drosophila gene regulatory protein Antennapedia by a segment synthesis-condensation approach Journal of Organic Chemistry. 58: 2209-2215. DOI: 10.1021/Jo00060A042 |
0.557 |
|
| 1993 |
Franciskovich J, Houseman K, Mueller R, Chmielewski J. A systematic evaluation of the inhibition of HIV-1 protease by its C- and N-terminal peptides Bioorganic & Medicinal Chemistry Letters. 3: 765-768. DOI: 10.1016/S0960-894X(01)81271-3 |
0.382 |
|
| 1993 |
Lutgring R, Sujatha K, Chmielewski J. Synthesis of homologs of cysteine suitable for peptide and protein crosslinking Bioorganic & Medicinal Chemistry Letters. 3: 739-742. DOI: 10.1016/S0960-894X(01)81265-8 |
0.811 |
|
| 1993 |
Bishop P, Jones C, Chmielewski J. Dimethyl(methylthio)sulfonium tetrafluoroborate: A reagent for disulfide bond formation in peptides Tetrahedron Letters. 34: 4469-4472. DOI: 10.1016/0040-4039(93)88061-M |
0.786 |
|
| 1992 |
Bishop P, Chmielewski J. Cyanogen iodide: A new reagent for disulfide bond formation in peptides Tetrahedron Letters. 33: 6263-6266. DOI: 10.1016/S0040-4039(00)60948-6 |
0.779 |
|
| 1991 |
Jackson DY, King DS, Chmielewski J, Singh S, Schultz PG. General approach to the synthesis of short .alpha.-helical peptides Journal of the American Chemical Society. 113: 9391-9392. DOI: 10.1021/Ja00024A067 |
0.755 |
|
| 1988 |
Breslow R, Chmielewski J, Foley D, Johnson B, Kumabe N, Varney M, Mehra R. Optically Active Amino Acid Synthesis by Artificial Transaminase Enzymes Tetrahedron. 44: 5515-5524. DOI: 10.1016/S0040-4020(01)86057-9 |
0.445 |
|
| 1987 |
Chmielewski J, Breslow R. Increasing the racemase activity versus transaminase activity of a pyridoxal enzyme model by the attachment of a rigid base Heterocycles. 25: 533-540. DOI: 10.3987/S-1987-01-0533 |
0.438 |
|
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