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Benjamin T. Houseman, Ph.D. - Publications

Affiliations: 
2001 University of Chicago, Chicago, IL 
Area:
chemical biology of cell adhesion
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Diaz-Flores E, Goldschmidt H, Depeille P, Ng V, Akutagawa J, Krisman K, Crone M, Burgess MR, Williams O, Houseman B, Shokat K, Sampath D, Bollag G, Roose JP, Braun BS, et al. PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. Science Signaling. 6: ra105. PMID 24300897 DOI: 10.1126/Scisignal.2004125  0.659
2012 Cheng CK, Gustafson WC, Charron E, Houseman BT, Zunder E, Goga A, Gray NS, Pollok B, Oakes SA, James CD, Shokat KM, Weiss WA, Fan QW. Dual blockade of lipid and cyclin-dependent kinases induces synthetic lethality in malignant glioma. Proceedings of the National Academy of Sciences of the United States of America. 109: 12722-7. PMID 22802621 DOI: 10.1073/Pnas.1202492109  0.746
2011 Nakamura JL, Phong C, Pinarbasi E, Kogan SC, Vandenberg S, Horvai AE, Faddegon BA, Fiedler D, Shokat K, Houseman BT, Chao R, Pieper RO, Shannon K. Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice. Cancer Research. 71: 106-15. PMID 21199799 DOI: 10.1158/0008-5472.Can-10-2732  0.586
2010 Fan QW, Cheng C, Hackett C, Feldman M, Houseman BT, Nicolaides T, Haas-Kogan D, James CD, Oakes SA, Debnath J, Shokat KM, Weiss WA. Akt and autophagy cooperate to promote survival of drug-resistant glioma. Science Signaling. 3: ra81. PMID 21062993 DOI: 10.1126/Scisignal.2001017  0.571
2010 Gomez-Sjoberg R, Leyrat AA, Houseman BT, Shokat K, Quake SR. Biocompatibility and reduced drug absorption of sol-gel-treated poly(dimethyl siloxane) for microfluidic cell culture applications. Analytical Chemistry. 82: 8954-60. PMID 20936785 DOI: 10.1021/Ac101870S  0.471
2010 Miller S, Tavshanjian B, Oleksy A, Perisic O, Houseman BT, Shokat KM, Williams RL. Shaping development of autophagy inhibitors with the structure of the lipid kinase Vps34. Science (New York, N.Y.). 327: 1638-42. PMID 20339072 DOI: 10.1126/science.1184429  0.699
2010 Williams O, Houseman BT, Kunkel EJ, Aizenstein B, Hoffman R, Knight ZA, Shokat KM. Discovery of dual inhibitors of the immune cell PI3Ks p110delta and p110gamma: a prototype for new anti-inflammatory drugs. Chemistry & Biology. 17: 123-34. PMID 20189103 DOI: 10.1016/J.Chembiol.2010.01.010  0.735
2010 Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Rückle T, Schwarz MK, Shokat KM, Shaw JP, et al. The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nature Chemical Biology. 6: 244. PMID 20154668 DOI: 10.1038/Nchembio0310-244B  0.666
2010 Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Rückle T, Schwarz MK, Shokat KM, Shaw JP, et al. The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nature Chemical Biology. 6: 117-24. PMID 20081827 DOI: 10.1038/Nchembio.293  0.685
2010 Roux J, Carles M, Koh H, Goolaerts A, Ganter MT, Chesebro BB, Howard M, Houseman BT, Finkbeiner W, Shokat KM, Paquet AC, Matthay MA, Pittet JF. Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism. The Journal of Biological Chemistry. 285: 4278-90. PMID 19996317 DOI: 10.1074/Jbc.M109.036731  0.399
2009 Herbert SP, Huisken J, Kim TN, Feldman ME, Houseman BT, Wang RA, Shokat KM, Stainier DY. Arterial-venous segregation by selective cell sprouting: an alternative mode of blood vessel formation. Science (New York, N.Y.). 326: 294-8. PMID 19815777 DOI: 10.1126/Science.1178577  0.626
2009 Sly LM, Hamilton MJ, Kuroda E, Ho VW, Antignano FL, Omeis SL, van Netten-Thomas CJ, Wong D, Brugger HK, Williams O, Feldman ME, Houseman BT, Fiedler D, Shokat KM, Krystal G. SHIP prevents lipopolysaccharide from triggering an antiviral response in mice. Blood. 113: 2945-54. PMID 19139077 DOI: 10.1182/Blood-2008-06-166082  0.716
2008 Papakonstanti EA, Zwaenepoel O, Bilancio A, Burns E, Nock GE, Houseman B, Shokat K, Ridley AJ, Vanhaesebroeck B. Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages. Journal of Cell Science. 121: 4124-33. PMID 19033389 DOI: 10.1242/Jcs.032763  0.563
2008 Zunder ER, Knight ZA, Houseman BT, Apsel B, Shokat KM. Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha. Cancer Cell. 14: 180-92. PMID 18691552 DOI: 10.1016/J.Ccr.2008.06.014  0.718
2003 Houseman BT, Gawalt ES, Mrksich M. Maleimide-functionalized self-assembled monolayers for the preparation of peptide and carbohydrate biochips Langmuir. 19: 1522-1531. DOI: 10.1021/La0262304  0.68
2002 Houseman BT, Mrksich M. Towards quantitative assays with peptide chips: a surface engineering approach. Trends in Biotechnology. 20: 279-81. PMID 12062966 DOI: 10.1016/S0167-7799(02)01984-4  0.457
2002 Houseman BT, Mrksich M. Carbohydrate arrays for the evaluation of protein binding and enzymatic modification. Chemistry & Biology. 9: 443-54. PMID 11983333 DOI: 10.1016/S1074-5521(02)00124-2  0.46
2002 Houseman BT, Huh JH, Kron SJ, Mrksich M. Peptide chips for the quantitative evaluation of protein kinase activity. Nature Biotechnology. 20: 270-4. PMID 11875428 DOI: 10.1038/Nbt0302-270  0.522
2001 Yousaf MN, Houseman BT, Mrksich M. Using electroactive substrates to pattern the attachment of two different cell populations. Proceedings of the National Academy of Sciences of the United States of America. 98: 5992-6. PMID 11353818 DOI: 10.1073/Pnas.101112898  0.588
2001 Houseman BT, Mrksich M. The microenvironment of immobilized Arg-Gly-Asp peptides is an important determinant of cell adhesion. Biomaterials. 22: 943-55. PMID 11311013 DOI: 10.1016/S0142-9612(00)00259-3  0.477
2001 Yousaf MN, Houseman BT, Mrksich M. Turning On Cell Migration with Electroactive Substrates We are grateful for support of this work by DARPA and the National Institute of Health (GM 54621). This work used facilities of the MRSEC supported by the National Science Foundation (DMR-9808595). M. M. is a Searle Scholar and an A. P. Sloan Fellow. B. T. Houseman is supported by MD/PhD Training Grant HD-09007. Angewandte Chemie (International Ed. in English). 40: 1093-1096. PMID 11268085 DOI: 10.1002/1521-3773(20010316)40:6<1093::AID-ANIE10930>3.0.CO;2-Q  0.549
2001 Yousaf MN, Houseman BT, Mrksich M. Turning on cell migration with electroactive substrates Angewandte Chemie - International Edition. 40: 1093-1096. DOI: 10.1002/1521-3773(20010316)40:6<1093::Aid-Anie10930>3.0.Co;2-Q  0.579
1999 Houseman BT, Mrksich M. The Role of Ligand Density in the Enzymatic Glycosylation of Carbohydrates Presented on Self-Assembled Monolayers of Alkanethiolates on Gold. Angewandte Chemie (International Ed. in English). 38: 782-785. PMID 29711797 DOI: 10.1002/(Sici)1521-3773(19990315)38:6<782::Aid-Anie782>3.0.Co;2-N  0.444
1999 Houseman BT, Mrksich M. The role of ligand density in the enzymatic glycosylation of carbohydrates presented on self-assembled monolayers of alkanethiolates on gold Angewandte Chemie - International Edition. 38: 782-785.  0.429
1998 Houseman BT, Mrksich M. Efficient Solid-Phase Synthesis of Peptide-Substituted Alkanethiols for the Preparation of Substrates That Support the Adhesion of Cells. The Journal of Organic Chemistry. 63: 7552-7555. PMID 11672416 DOI: 10.1021/Jo981113S  0.451
1997 Houseman BT, Mrksich M. Using self-assembled monolayers that present arg-gly -ASP peptide ligands to study adhesion of fibroblasts Faseb Journal. 11: A1094.  0.447
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