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Chaim A. Schramm, Ph.D. - Publications

Affiliations: 
2012 Biochemistry and Molecular Biophysics University of Pennsylvania, Philadelphia, PA, United States 
Area:
Organic Chemistry, Chemical Biology, De Novo Protein Design
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Roark RS, Li H, Williams WB, Chug H, Mason RD, Gorman J, Wang S, Lee FH, Rando J, Bonsignori M, Hwang KK, Saunders KO, Wiehe K, Moody MA, Hraber PT, ... ... Schramm CA, et al. Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science (New York, N.Y.). PMID 33214287 DOI: 10.1126/science.abd2638  0.305
2020 Wu NC, Andrews SF, Raab JE, O'Connell S, Schramm CA, Ding X, Chambers MJ, Leung K, Wang L, Zhang Y, Mascola JR, Douek DC, Ledgerwood JE, McDermott AB, Wilson IA. Convergent Evolution in Breadth of Two V6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host & Microbe. PMID 32619441 DOI: 10.1016/J.Chom.2020.06.003  0.352
2020 Rantalainen K, Berndsen ZT, Antanasijevic A, Schiffner T, Zhang X, Lee WH, Torres JL, Zhang L, Irimia A, Copps J, Zhou KH, Kwon YD, Law WH, Schramm CA, Verardi R, et al. HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies. Cell Reports. 31: 107583. PMID 32348769 DOI: 10.1016/J.Celrep.2020.107583  0.497
2019 Olson BJ, Moghimi P, Schramm CA, Obraztsova A, Ralph D, Vander Heiden JA, Shugay M, Shepherd AJ, Lees W, Matsen FA. sumrep: A Summary Statistic Framework for Immune Receptor Repertoire Comparison and Model Validation. Frontiers in Immunology. 10: 2533. PMID 31736960 DOI: 10.3389/Fimmu.2019.02533  0.324
2019 Gorman J, Mason RD, Nettey L, Cavett N, Chuang GY, Peng D, Tsybovsky Y, Verardi R, Nguyen R, Ambrozak D, Biris K, LaBranche CC, Ramesh A, Schramm CA, Zhou J, et al. Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields. Immunity. PMID 31586542 DOI: 10.1016/J.Immuni.2019.09.007  0.424
2019 Ohlin M, Scheepers C, Corcoran M, Lees WD, Busse CE, Bagnara D, Thörnqvist L, Bürckert JP, Jackson KJL, Ralph D, Schramm CA, Marthandan N, Breden F, Scott J, Matsen Iv FA, et al. Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming. Frontiers in Immunology. 10: 435. PMID 30936866 DOI: 10.3389/Fimmu.2019.00435  0.305
2019 Krebs SJ, Kwon YD, Schramm CA, Law WH, Donofrio G, Zhou KH, Gift S, Dussupt V, Georgiev IS, Schätzle S, McDaniel JR, Lai YT, Sastry M, Zhang B, Jarosinski MC, et al. Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity. PMID 30876875 DOI: 10.1016/J.Immuni.2019.02.008  0.421
2019 Corbett KS, Moin SM, Yassine HM, Cagigi A, Kanekiyo M, Boyoglu-Barnum S, Myers SI, Tsybovsky Y, Wheatley AK, Schramm CA, Gillespie RA, Shi W, Wang L, Zhang Y, Andrews SF, et al. Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages. Mbio. 10. PMID 30808695 DOI: 10.1128/Mbio.02810-18  0.354
2018 Vander Heiden JA, Marquez S, Marthandan N, Bukhari SAC, Busse CE, Corrie B, Hershberg U, Kleinstein SH, Matsen Iv FA, Ralph DK, Rosenfeld AM, Schramm CA, Christley S, Laserson U. AIRR Community Standardized Representations for Annotated Immune Repertoires. Frontiers in Immunology. 9: 2206. PMID 30323809 DOI: 10.3389/Fimmu.2018.02206  0.307
2018 Johnson EL, Doria-Rose NA, Gorman J, Bhiman JN, Schramm CA, Vu AQ, Law WH, Zhang B, Bekker V, Abdool Karim SS, Ippolito GC, Morris L, Moore PL, Kwong PD, Mascola JR, et al. Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation. Nature Communications. 9: 4136. PMID 30297708 DOI: 10.1038/S41467-018-06424-6  0.399
2018 Schramm CA, Douek DC. Beyond Hot Spots: Biases in Antibody Somatic Hypermutation and Implications for Vaccine Design. Frontiers in Immunology. 9: 1876. PMID 30154794 DOI: 10.3389/Fimmu.2018.01876  0.349
2017 Sheng Z, Schramm CA, Kong R, Mullikin JC, Mascola JR, Kwong PD, Shapiro L. Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation. Frontiers in Immunology. 8: 537. PMID 28539926 DOI: 10.3389/Fimmu.2017.00537  0.351
2017 Kwong PD, Chuang GY, DeKosky BJ, Gindin T, Georgiev IS, Lemmin T, Schramm CA, Sheng Z, Soto C, Yang AS, Mascola JR, Shapiro L. Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1. Immunological Reviews. 275: 108-128. PMID 28133812 DOI: 10.1111/Imr.12480  0.397
2016 Huang J, Kang BH, Ishida E, Zhou T, Griesman T, Sheng Z, Wu F, Doria-Rose NA, Zhang B, McKee K, O'Dell S, Chuang GY, Druz A, Georgiev IS, Schramm CA, et al. Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. Immunity. 45: 1108-1121. PMID 27851912 DOI: 10.1016/J.Immuni.2016.10.027  0.345
2016 Schramm CA, Sheng Z, Zhang Z, Mascola JR, Kwong PD, Shapiro L. SONAR: A High-Throughput Pipeline for Inferring Antibody Ontogenies from Longitudinal Sequencing of B Cell Transcripts. Frontiers in Immunology. 7: 372. PMID 27708645 DOI: 10.3389/Fimmu.2016.00372  0.343
2016 Sheng Z, Schramm CA, Connors M, Morris L, Mascola JR, Kwong PD, Shapiro L. Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection. Plos Computational Biology. 12: e1004940. PMID 27191167 DOI: 10.1371/Journal.Pcbi.1004940  0.377
2016 Bonsignori M, Zhou T, Sheng Z, Chen L, Gao F, Joyce MG, Ozorowski G, Chuang GY, Schramm CA, Wiehe K, Alam SM, Bradley T, Gladden MA, Hwang KK, Iyengar S, et al. Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. Cell. PMID 26949186 DOI: 10.1016/J.Cell.2016.02.022  0.34
2015 Doria-Rose NA, Bhiman JN, Roark RS, Schramm CA, Gorman J, Chuang GY, Pancera M, Cale EM, Ernandes MJ, Louder MK, Asokan M, Bailer RT, Druz A, Fraschilla IR, Garrett NJ, et al. A new member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency. Journal of Virology. PMID 26468542 DOI: 10.1128/Jvi.01791-15  0.392
2015 Bhiman JN, Anthony C, Doria-Rose NA, Karimanzira O, Schramm CA, Khoza T, Kitchin D, Botha G, Gorman J, Garrett NJ, Abdool Karim SS, Shapiro L, Williamson C, Kwong PD, Mascola JR, et al. Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies. Nature Medicine. 21: 1332-6. PMID 26457756 DOI: 10.1038/Nm.3963  0.4
2015 Wu X, Zhang Z, Schramm CA, Joyce MG, Kwon YD, Zhou T, Sheng Z, Zhang B, O'Dell S, McKee K, Georgiev IS, Chuang GY, Longo NS, Lynch RM, Saunders KO, et al. Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell. 161: 470-85. PMID 25865483 DOI: 10.1016/J.Cell.2015.03.004  0.384
2015 Zhang SQ, Kulp DW, Schramm CA, Mravic M, Samish I, DeGrado WF. The membrane- and soluble-protein helix-helix interactome: similar geometry via different interactions. Structure (London, England : 1993). 23: 527-41. PMID 25703378 DOI: 10.1016/J.Str.2015.01.009  0.624
2014 Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 509: 55-62. PMID 24590074 DOI: 10.1038/Nature13036  0.392
2014 Doria-Rose NA, Roark RS, Moore P, Ernandes MJ, Bhiman JN, Schramm CA, McKee K, O'Dell S, Louder M, Karim SSA, Shapiro L, Morris L, Mascola JR. Variable Dependence on Glycan Recognition within a Lineage of V1V2-directed HIV Neutralizing Antibodies Aids Research and Human Retroviruses. 30: A88-A89. DOI: 10.1089/Aid.2014.5161.Abstract  0.397
2013 Zhou T, Zhu J, Wu X, Moquin S, Zhang B, Acharya P, Georgiev IS, Altae-Tran HR, Chuang GY, Joyce MG, Do Kwon Y, Longo NS, Louder MK, Luongo T, McKee K, ... Schramm CA, et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity. 39: 245-58. PMID 23911655 DOI: 10.1016/J.Immuni.2013.04.012  0.403
2013 Liao HX, Lynch R, Zhou T, Gao F, Munir Alam S, Boyd SD, Fire AZ, Roskin KM, Schramm CA, Zhang Z, Zhu J, Shapiro L, Mullikin JC, Gnanakaran S, Hraber P, et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Nature. 496: 469-476. PMID 23552890 DOI: 10.1038/Nature12053  0.405
2012 Schramm CA, Hannigan BT, Donald JE, Keasar C, Saven JG, Degrado WF, Samish I. Knowledge-based potential for positioning membrane-associated structures and assessing residue-specific energetic contributions. Structure (London, England : 1993). 20: 924-35. PMID 22579257 DOI: 10.1016/J.Str.2012.03.016  0.589
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