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Nina H. Pipalia, Ph.D. - Publications

Affiliations: 
2003 Loyola University Chicago, Chicago, IL, United States 
Area:
Biochemistry, Medical Biophysics, Pathology
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Tcw J, Qian L, Pipalia NH, Chao MJ, Liang SA, Shi Y, Jain BR, Bertelsen SE, Kapoor M, Marcora E, Sikora E, Andrews EJ, Martini AC, Karch CM, Head E, et al. Cholesterol and matrisome pathways dysregulated in astrocytes and microglia. Cell. 185: 2213-2233.e25. PMID 35750033 DOI: 10.1016/j.cell.2022.05.017  0.529
2021 Pipalia NH, Saad SZ, Subramanian K, Cross A, Al-Motawa A, Garg K, Blagg BSJ, Neckers L, Helquist P, Wiest O, Ory DS, Maxfield FR. HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts. Journal of Lipid Research. 100114. PMID 34481829 DOI: 10.1016/j.jlr.2021.100114  0.728
2021 Cruz DL, Pipalia N, Mao S, Gadi D, Liu G, Grigalunas M, O'Neill M, Quinn TR, Kipper A, Ekebergh A, Dimmling A, Gartner C, Melancon BJ, Wagner FF, Holson E, et al. Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts. Acs Pharmacology & Translational Science. 4: 1136-1148. PMID 34151204 DOI: 10.1021/acsptsci.1c00033  0.637
2019 Davidson J, Molitor E, Moores S, Gale SE, Subramanian K, Jiang X, Sidhu R, Kell P, Zhang J, Fujiwara H, Davidson C, Helquist P, Melancon BJ, Grigalunas M, Liu G, ... ... Pipalia NH, et al. 2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. PMID 31051283 DOI: 10.1016/J.Bbalip.2019.04.011  0.587
2018 Crespo M, Vilar E, Tsai SY, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJ, Witherspoon M, Gordillo M, Xiang JZ, Maxfield FR, Lipkin S, Evans T, et al. Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. Nature Medicine. 24: 526. PMID 29634683 DOI: 10.1038/Nm0418-526A  0.505
2017 Jena PV, Roxbury D, Galassi TV, Akkari L, Horoszko CP, Iaea DB, Budhathoki-Uprety J, Pipalia N, Haka AS, Harvey JD, Mittal J, Maxfield FR, Joyce JA, Heller DA. A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux. Acs Nano. PMID 28898055 DOI: 10.1021/Acsnano.7B04743  0.596
2017 Crespo M, Vilar E, Tsai SY, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJ, Witherspoon M, Gordillo M, Xiang JZ, Maxfield FR, Lipkin S, Evans T, et al. Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. Nature Medicine. PMID 28628110 DOI: 10.1038/Nm.4355  0.561
2017 Pipalia NH, Subramanian K, Mao S, Ralph H, Hutt DM, Scott SM, Balch WE, Maxfield FR. Histone deacetylase inhibitors correct the cholesterol storage defect in most NPC1 mutant cells. Journal of Lipid Research. PMID 28193631 DOI: 10.1194/Jlr.M072140  0.683
2016 Maxfield FR, Iaea DB, Pipalia NH. Role of STARD4 and NPC1 in intracellular sterol transport. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 1-8. PMID 27421092 DOI: 10.1139/Bcb-2015-0154  0.61
2015 Praggastis M, Tortelli B, Zhang J, Fujiwara H, Sidhu R, Chacko A, Chen Z, Chung C, Lieberman AP, Sikora J, Davidson C, Walkley SU, Pipalia NH, Maxfield FR, Schaffer JE, et al. A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8091-106. PMID 26019327 DOI: 10.1523/Jneurosci.4173-14.2015  0.618
2014 Pipalia NH, Maxfield FR. Therapeutic potential of histone deacetylase inhibitor for treatment of Niemann-Pick type C1 disease Molecular Cytogenetics. DOI: 10.1186/1755-8166-7-S1-O2  0.636
2012 Yao J, Ho D, Calingasan NY, Pipalia NH, Lin MT, Beal MF. Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease. The Journal of Experimental Medicine. 209: 2501-13. PMID 23209315 DOI: 10.1084/Jem.20121239  0.368
2012 Tortorella LL, Pipalia NH, Mukherjee S, Pastan I, Fitzgerald D, Maxfield FR. Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary. Plos One. 7: e47320. PMID 23056628 DOI: 10.1371/Journal.Pone.0047320  0.61
2011 Mesmin B, Pipalia NH, Lund FW, Ramlall TF, Sokolov A, Eliezer D, Maxfield FR. STARD4 abundance regulates sterol transport and sensing. Molecular Biology of the Cell. 22: 4004-15. PMID 21900492 DOI: 10.1091/Mbc.E11-04-0372  0.599
2011 Pipalia NH, Cosner CC, Huang A, Chatterjee A, Bourbon P, Farley N, Helquist P, Wiest O, Maxfield FR. Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 108: 5620-5. PMID 21436030 DOI: 10.1073/Pnas.1014890108  0.662
2010 Rujoi M, Pipalia NH, Maxfield FR. Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells. Plos One. 5: e12788. PMID 20877719 DOI: 10.1371/Journal.Pone.0012788  0.66
2010 Devlin C, Pipalia NH, Liao X, Schuchman EH, Maxfield FR, Tabas I. Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect. Traffic (Copenhagen, Denmark). 11: 601-15. PMID 20412078 DOI: 10.1111/J.1600-0854.2010.01046.X  0.633
2010 Song Y, Pipalia NH, Fung LW-. The L49F Mutation in Erythroid Alpha Spectrin Induces Local Disorder in the Tetramer Association Region: Fluorescence And Molecular Dynamics Studies of Free and Bound Alpha Spectrin Biophysical Journal. 98: 2-2. DOI: 10.1016/J.Bpj.2009.12.1255  0.347
2009 Song Y, Pipalia NH, Fung LW. The L49F mutation in alpha erythroid spectrin induces local disorder in the tetramer association region: Fluorescence and molecular dynamics studies of free and bound alpha spectrin. Protein Science : a Publication of the Protein Society. 18: 1916-25. PMID 19593814 DOI: 10.1002/Pro.202  0.607
2007 Pipalia NH, Hao M, Mukherjee S, Maxfield FR. Sterol, protein and lipid trafficking in Chinese hamster ovary cells with Niemann-Pick type C1 defect. Traffic (Copenhagen, Denmark). 8: 130-41. PMID 17156101 DOI: 10.1111/J.1600-0854.2006.00513.X  0.653
2006 Walczak W, Pipalia NH, Soni M, Faruqi AF, Ralph H, Maxfield FR, Webb BL. Parallel analysis of v-Src mutant protein function using reverse transfection cell arrays. Combinatorial Chemistry & High Throughput Screening. 9: 711-8. PMID 17100576 DOI: 10.2174/138620706778700116  0.569
2006 Pipalia NH, Huang A, Ralph H, Rujoi M, Maxfield FR. Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells. Journal of Lipid Research. 47: 284-301. PMID 16288097 DOI: 10.1194/Jlr.M500388-Jlr200  0.586
2005 Raja SM, Metkar SS, Höning S, Wang B, Russin WA, Pipalia NH, Menaa C, Belting M, Cao X, Dressel R, Froelich CJ. A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells. The Journal of Biological Chemistry. 280: 20752-61. PMID 15788411 DOI: 10.1074/Jbc.M501181200  0.333
2002 Luo BH, Mehboob S, Hurtuk MG, Pipalia NH, Fung LW. Important region in the beta-spectrin C-terminus for spectrin tetramer formation. European Journal of Haematology. 68: 73-9. PMID 12038451 DOI: 10.1034/j.1600-0609.2002.01569.x  0.611
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