| Year |
Citation |
Score |
| 2024 |
Cramer NA, Socarras KM, Earl J, Ehrlich GD, Marconi RT. factor H-binding proteins are not required for serum resistance and infection in mammals. Infection and Immunity. e0052923. PMID 38289123 DOI: 10.1128/iai.00529-23 |
0.449 |
|
| 2022 |
Camire AC, O'Bier NS, Patel DT, Cramer NA, Straubinger RK, Breitschwerdt EB, Funk RA, Marconi RT. FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease. Infection and Immunity. 90: e0036422. PMID 36102656 DOI: 10.1128/iai.00364-22 |
0.34 |
|
| 2021 |
Ante VM, Farris LC, Saputra EP, Hall AJ, O'Bier NS, Oliva Chávez AS, Marconi RT, Lybecker MC, Hyde JA. The Adenylate Cyclase, CyaB, Is Important for Virulence Factor Production and Mammalian Infection. Frontiers in Microbiology. 12: 676192. PMID 34113333 DOI: 10.3389/fmicb.2021.676192 |
0.312 |
|
| 2020 |
OBier NS, Patel DT, Oliver LD, Miller DP, Marconi RT. Development of an FhbB based chimeric vaccinogen that elicits antibodies that block Factor H binding and cleavage by the periopathogen Treponema denticola. Molecular Oral Microbiology. PMID 33219611 DOI: 10.1111/omi.12325 |
0.339 |
|
| 2020 |
Hatke AL, Green DR, Stasiak K, Marconi RT. Antibody profiling of a Borreliella burgdorferi (Lyme disease) C6 antibody positive, symptomatic Rottweiler and her pups. Veterinary Journal (London, England : 1997). 262: 105504. PMID 32792093 DOI: 10.1016/J.Tvjl.2020.105504 |
0.31 |
|
| 2020 |
Naimi WA, Gumpf JJ, Green RS, Izac JR, Zellner MP, Conrad DH, Marconi RT, Martin RK, Carlyon JA. Immunization against adhesin binding domains confers protection against infection in the mouse model. Infection and Immunity. PMID 32661123 DOI: 10.1128/Iai.00106-20 |
0.417 |
|
| 2020 |
Green RS, Naimi WA, Oliver LD, O'Bier N, Cho J, Conrad DH, Martin RK, Marconi RT, Carlyon JA. Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection. Mbio. 11. PMID 31992623 DOI: 10.1128/Mbio.03141-19 |
0.441 |
|
| 2020 |
Izac JR, O'Bier NS, Oliver LD, Camire AC, Earnhart CG, LeBlanc Rhodes DV, Young BF, Parnham SR, Davies C, Marconi RT. Development and optimization of OspC chimeritope vaccinogens for Lyme disease. Vaccine. PMID 31959423 DOI: 10.1016/J.Vaccine.2020.01.027 |
0.419 |
|
| 2019 |
Gomes-Solecki M, Arnaboldi PM, Backenson PB, Benach JL, Cooper CL, Dattwyler RJ, Diuk-Wasser M, Fikrig E, Hovius JW, Laegreid W, Lundberg U, Marconi RT, Marques AR, Molloy P, Narasimhan S, et al. Protective Immunity and New Vaccines for Lyme Disease. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 31620776 DOI: 10.1093/Cid/Ciz872 |
0.359 |
|
| 2019 |
Caimano MJ, Groshong AM, Belperron A, Mao J, Hawley KL, Luthra A, Graham DE, Earnhart CG, Marconi RT, Bockenstedt LK, Blevins JS, Radolf JD. The RpoS Gatekeeper in : An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity. Frontiers in Microbiology. 10: 1923. PMID 31507550 DOI: 10.3389/Fmicb.2019.01923 |
0.405 |
|
| 2019 |
Izac JR, Marconi RT. Diversity of the Lyme Disease Spirochetes and its Influence on Immune Responses to Infection and Vaccination. The Veterinary Clinics of North America. Small Animal Practice. PMID 30967254 DOI: 10.1016/J.Cvsm.2019.02.007 |
0.348 |
|
| 2019 |
Izac JR, Camire AC, Earnhart CG, Embers ME, Funk RA, Breitschwerdt EB, Marconi RT. Analysis of the antigenic determinants of the OspC protein of the Lyme disease spirochetes: Evidence that the C10 motif is not immunodominant or required to elicit bactericidal antibody responses. Vaccine. PMID 30922701 DOI: 10.1016/J.Vaccine.2019.02.007 |
0.408 |
|
| 2018 |
Evans SM, Adcox HE, VieBrock L, Green RS, Luce-Fedrow A, Chattopadhyay S, Jiang J, Marconi RT, Paris D, Richards AL, Carlyon JA. Outer Membrane Protein A Conservation among Isolates Suggests Its Potential as a Protective Antigen and Diagnostic Target. Tropical Medicine and Infectious Disease. 3. PMID 30274459 DOI: 10.3390/Tropicalmed3020063 |
0.369 |
|
| 2018 |
Kostick-Dunn JL, Izac JR, Freedman JC, Szkotnicki LT, Oliver LD, Marconi RT. The c-di-GMP Binding Receptors, PlzA and PlzB, Are Functionally Distinct. Frontiers in Cellular and Infection Microbiology. 8: 213. PMID 30050868 DOI: 10.3389/Fcimb.2018.00213 |
0.452 |
|
| 2018 |
Sarkar J, Miller DP, Oliver LD, Marconi RT. The PAS domain containing histidine kinase, Hpk2, is a heme binding sensor of oxygen levels. Journal of Bacteriology. PMID 29986942 DOI: 10.1128/Jb.00116-18 |
0.632 |
|
| 2018 |
Tegels BK, Oliver LD, Miller DP, Marconi RT. Plasminogen binding and degradation by Treponema denticola: identification of the plasminogen binding interface on the FhbB protein. Molecular Oral Microbiology. PMID 29498487 DOI: 10.1111/Omi.12221 |
0.526 |
|
| 2017 |
Marconi RT. Gene Regulation, Two Component Regulatory Systems, and Adaptive Responses in Treponema Denticola. Current Topics in Microbiology and Immunology. PMID 29026924 DOI: 10.1007/82_2017_66 |
0.323 |
|
| 2017 |
Izac JR, Oliver LD, Earnhart CG, Marconi RT. Identification of a defined linear epitope in the OspA protein of the Lyme disease spirochetes that elicits bactericidal antibody responses: Implications for vaccine development. Vaccine. PMID 28479174 DOI: 10.1016/J.Vaccine.2017.04.079 |
0.315 |
|
| 2017 |
Neelakanta G, Sultana H, Sonenshine DE, Marconi RT. An In Vitro Blood-Feeding Method Revealed Differential Borrelia turicatae (Spirochaetales: Spirochaetaceae) Gene Expression After Spirochete Acquisition and Colonization in the Soft Tick Ornithodoros turicata (Acari: Argasidae). Journal of Medical Entomology. 54: 441-449. PMID 28399292 DOI: 10.1093/Jme/Tjw171 |
0.383 |
|
| 2017 |
Beyer AR, Rodino KG, VieBrock L, Green RS, Tegels BK, Oliver LD, Marconi RT, Carlyon JA. Orientia tsutsugamushi Ank9 is a multifunctional effector that utilizes a novel GRIP-like Golgi localization domain for Golgi-to-endoplasmic reticulum trafficking and interacts with host COPB2. Cellular Microbiology. PMID 28103630 DOI: 10.1111/Cmi.12727 |
0.41 |
|
| 2016 |
Hebert KS, Seidman D, Oki AT, Izac J, Emani S, Oliver LD, Miller DP, Tegels BK, Kannagi R, Marconi RT, Carlyon JA. Anaplasma marginale outer membrane protein A is an adhesin that recognizes sialylated and fucosylated glycans and functionally depends on an essential binding domain. Infection and Immunity. PMID 27993973 DOI: 10.1128/Iai.00968-16 |
0.432 |
|
| 2016 |
Oliver LD, Earnhart CG, Virginia-Rhodes D, Theisen M, Marconi RT. Antibody profiling of canine IgG responses to the OspC protein of the Lyme disease spirochetes supports a multivalent approach in vaccine and diagnostic assay development. Veterinary Journal (London, England : 1997). 218: 27-33. PMID 27938705 DOI: 10.1016/J.Tvjl.2016.11.001 |
0.37 |
|
| 2016 |
Mallory KL, Miller DP, Oliver LD, Freedman JC, Kostick-Dunn JL, Carlyon JA, Marion JD, Bell JK, Marconi RT. Cyclic-di-GMP binding induces structural rearrangements in the PlzA and PlzC proteins of the Lyme disease and relapsing fever spirochetes: a possible switch mechanism for c-di-GMP-mediated effector functions. Pathogens and Disease. 74. PMID 27852620 DOI: 10.1093/Femspd/Ftw105 |
0.432 |
|
| 2016 |
Miller DP, Oliver LD, Tegels BK, Reed LA, O'Bier N, Kurniyati K, Faust LA, Lawson CK, Allard AM, Caimano MJ, Marconi RT. The Treponema denticola FhbB protein is a dominant early antigen that elicits FhbB variant specific antibodies that block factor H binding and cleavage by dentilisin. Infection and Immunity. PMID 27113359 DOI: 10.1128/Iai.01542-15 |
0.5 |
|
| 2015 |
Beyer AR, VieBrock L, Rodino KG, Miller DP, Tegels BK, Marconi RT, Carlyon JA. Orientia tsutsugamushi Strain Ikeda Ankyrin Repeat-Containing Proteins Recruit SCF1 Ubiquitin Ligase Machinery via Poxvirus-Like F-Box Motifs. Journal of Bacteriology. 197: 3097-109. PMID 26170417 DOI: 10.1128/Jb.00276-15 |
0.382 |
|
| 2015 |
Seidman D, Hebert KS, Truchan HK, Miller DP, Tegels BK, Marconi RT, Carlyon JA. Essential domains of Anaplasma phagocytophilum invasins utilized to infect mammalian host cells. Plos Pathogens. 11: e1004669. PMID 25658707 DOI: 10.1371/Journal.Ppat.1004669 |
0.467 |
|
| 2014 |
Miller DP, Frederick JR, Sarkar J, Marconi RT. The Treponema denticola AtcR LytTR domain-containing response regulator interacts with three architecturally distinct promoter elements: implications for understanding the molecular signaling mechanisms that drive the progression of periodontal disease. Molecular Oral Microbiology. 29: 219-32. PMID 24890414 DOI: 10.1111/Omi.12059 |
0.646 |
|
| 2014 |
Fine LM, Miller DP, Mallory KL, Tegels BK, Earnhart CG, Marconi RT. The Borrelia hermsii factor H binding protein FhbA is not required for infectivity in mice or for resistance to human complement in vitro. Infection and Immunity. 82: 3324-32. PMID 24866803 DOI: 10.1128/Iai.01892-14 |
0.514 |
|
| 2014 |
Miller DP, McDowell JV, Bell JK, Goetting-Minesky MP, Fenno JC, Marconi RT. Analysis of the complement sensitivity of oral treponemes and the potential influence of FH binding, FH cleavage and dentilisin activity on the pathogenesis of periodontal disease. Molecular Oral Microbiology. 29: 194-207. PMID 24815960 DOI: 10.1111/Omi.12054 |
0.481 |
|
| 2014 |
Seidman D, Ojogun N, Walker NJ, Mastronunzio J, Kahlon A, Hebert KS, Karandashova S, Miller DP, Tegels BK, Marconi RT, Fikrig E, Borjesson DL, Carlyon JA. Anaplasma phagocytophilum surface protein AipA mediates invasion of mammalian host cells. Cellular Microbiology. 16: 1133-45. PMID 24612118 DOI: 10.1111/Cmi.12286 |
0.391 |
|
| 2014 |
Earnhart CG, Rhodes DV, Smith AA, Yang X, Tegels B, Carlyon JA, Pal U, Marconi RT. Assessment of the potential contribution of the highly conserved C-terminal motif (C10) of Borrelia burgdorferi outer surface protein C in transmission and infectivity. Pathogens and Disease. 70: 176-84. PMID 24376161 DOI: 10.1111/2049-632X.12119 |
0.44 |
|
| 2013 |
Rhodes DV, Earnhart CG, Mather TN, Meeus PF, Marconi RT. Identification of Borrelia burgdorferi ospC genotypes in canine tissue following tick infestation: implications for Lyme disease vaccine and diagnostic assay design. Veterinary Journal (London, England : 1997). 198: 412-8. PMID 23962611 DOI: 10.1016/J.Tvjl.2013.07.019 |
0.383 |
|
| 2013 |
Meri T, Amdahl H, Lehtinen MJ, Hyvärinen S, McDowell JV, Bhattacharjee A, Meri S, Marconi R, Goldman A, Jokiranta TS. Microbes bind complement inhibitor factor H via a common site. Plos Pathogens. 9: e1003308. PMID 23637600 DOI: 10.1371/Journal.Ppat.1003308 |
0.51 |
|
| 2013 |
Miller DP, McDowell JV, Rhodes DV, Allard A, Caimano M, Bell JK, Marconi RT. Sequence divergence in the Treponema denticola FhbB protein and its impact on factor H binding. Molecular Oral Microbiology. 28: 316-30. PMID 23601078 DOI: 10.1111/Omi.12027 |
0.477 |
|
| 2013 |
Meri T, Amdahl H, Lehtinen MJ, Hyvärinen S, McDowell JV, Bhattacharjee A, Meri S, Marconi R, Goldman A, Jokiranta TS. Correction: Microbes Bind Complement Inhibitor Factor H via a Common Site Plos Pathogens. 9. DOI: 10.1371/Annotation/41169409-3260-4295-Baf4-A1A4621A8E48 |
0.316 |
|
| 2013 |
Tegels B, Miller D, Marconi R. Characterization of plasminogen binding to factor H binding protein (FhbB) of the periopathogen Treponema denticola Molecular Immunology. 56: 315. DOI: 10.1016/J.Molimm.2013.05.249 |
0.517 |
|
| 2013 |
Miller D, Fine L, Marconi R. Genetic manipulation of the relapsing fever spirochete Borrelia hermsii permits study of the role of factor H binding and a novel complement evasion mechanism Molecular Immunology. 56: 314-315. DOI: 10.1016/J.Molimm.2013.05.248 |
0.448 |
|
| 2012 |
Miller DP, Bell JK, McDowell JV, Conrad DH, Burgner JW, Héroux A, Marconi RT. Structure of factor H-binding protein B (FhbB) of the periopathogen, Treponema denticola: insights into progression of periodontal disease. The Journal of Biological Chemistry. 287: 12715-22. PMID 22371503 DOI: 10.1074/Jbc.M112.339721 |
0.517 |
|
| 2012 |
Wagner B, Freer H, Rollins A, Garcia-Tapia D, Erb HN, Earnhart C, Marconi R, Meeus P. Antibodies to Borrelia burgdorferi OspA, OspC, OspF, and C6 antigens as markers for early and late infection in dogs. Clinical and Vaccine Immunology : Cvi. 19: 527-35. PMID 22336289 DOI: 10.1128/Cvi.05653-11 |
0.33 |
|
| 2012 |
Miller DP, McDowell JJ, Bell JK, Fenno JC, Marconi RT. Analysis of the unique interaction of factor H with the periopathogen Treponema denticola: The paradox of factor H cleavage Immunobiology. 217: 1139. DOI: 10.1016/J.Imbio.2012.08.029 |
0.365 |
|
| 2011 |
Marconi RT, McDowell JV. Tick salivary proteins offer the lyme disease spirochetes an easy ride and another way to hide. Cell Host & Microbe. 10: 95-6. PMID 21843866 DOI: 10.1016/J.Chom.2011.08.003 |
0.407 |
|
| 2011 |
Miller DP, McDowell JV, Bell JK, Marconi RT. Crystallization of the factor H-binding protein, FhbB, from the periopathogen Treponema denticola. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 678-81. PMID 21636910 DOI: 10.1107/S1744309111011298 |
0.504 |
|
| 2011 |
Fine LM, Earnhart CG, Marconi RT. Genetic transformation of the relapsing fever spirochete Borrelia hermsii: stable integration and expression of green fluorescent protein from linear plasmid 200. Journal of Bacteriology. 193: 3241-5. PMID 21551306 DOI: 10.1128/Jb.05037-11 |
0.4 |
|
| 2011 |
Kostick JL, Szkotnicki LT, Rogers EA, Bocci P, Raffaelli N, Marconi RT. The diguanylate cyclase, Rrp1, regulates critical steps in the enzootic cycle of the Lyme disease spirochetes. Molecular Microbiology. 81: 219-31. PMID 21542866 DOI: 10.1111/J.1365-2958.2011.07687.X |
0.372 |
|
| 2011 |
Earnhart CG, Rhodes DV, Marconi RT. Disulfide-mediated oligomer formation in Borrelia burgdorferi outer surface protein C, a critical virulence factor and potential Lyme disease vaccine candidate. Clinical and Vaccine Immunology : Cvi. 18: 901-6. PMID 21525304 DOI: 10.1128/Cvi.05004-11 |
0.366 |
|
| 2011 |
Frederick JR, Sarkar J, McDowell JV, Marconi RT. Molecular signaling mechanisms of the periopathogen, Treponema denticola. Journal of Dental Research. 90: 1155-63. PMID 21447698 DOI: 10.1177/0022034511402994 |
0.578 |
|
| 2011 |
McDowell JV, Frederick J, Miller DP, Goetting-Minesky MP, Goodman H, Fenno JC, Marconi RT. Identification of the primary mechanism of complement evasion by the periodontal pathogen, Treponema denticola. Molecular Oral Microbiology. 26: 140-9. PMID 21375704 DOI: 10.1111/J.2041-1014.2010.00598.X |
0.474 |
|
| 2011 |
Meri T, Lehtinen M, Amdahl H, McDowell J, Marconi R, Meri S, Goldman A, Jokiranta T. Several microbes mimic self surfaces in binding factor H via a conserved site on FH20—A universal target for immune escape? Molecular Immunology. 48: 1698-1699. DOI: 10.1016/J.Molimm.2011.06.322 |
0.397 |
|
| 2010 |
Sarkar J, Frederick J, Marconi RT. The Hpk2-Rrp2 two-component regulatory system of Treponema denticola: a potential regulator of environmental and adaptive responses. Molecular Oral Microbiology. 25: 241-51. PMID 20618698 DOI: 10.1111/J.2041-1014.2010.00578.X |
0.59 |
|
| 2010 |
Earnhart CG, Leblanc DV, Alix KE, Desrosiers DC, Radolf JD, Marconi RT. Identification of residues within ligand-binding domain 1 (LBD1) of the Borrelia burgdorferi OspC protein required for function in the mammalian environment. Molecular Microbiology. 76: 393-408. PMID 20199597 DOI: 10.1111/J.1365-2958.2010.07103.X |
0.453 |
|
| 2010 |
Freedman JC, Rogers EA, Kostick JL, Zhang H, Iyer R, Schwartz I, Marconi RT. Identification and molecular characterization of a cyclic-di-GMP effector protein, PlzA (BB0733): additional evidence for the existence of a functional cyclic-di-GMP regulatory network in the Lyme disease spirochete, Borrelia burgdorferi. Fems Immunology and Medical Microbiology. 58: 285-94. PMID 20030712 DOI: 10.1111/J.1574-695X.2009.00635.X |
0.507 |
|
| 2010 |
Marconi RT. Structure and mechanism of action of the FH binding FhbB protein of Treponema denticola Molecular Immunology. 47: 2245-2246. DOI: 10.1016/J.Molimm.2010.05.147 |
0.432 |
|
| 2009 |
Rogers EA, Abdunnur SV, McDowell JV, Marconi RT. Comparative analysis of the properties and ligand binding characteristics of CspZ, a factor H binding protein, derived from Borrelia burgdorferi isolates of human origin. Infection and Immunity. 77: 4396-405. PMID 19620346 DOI: 10.1128/Iai.00393-09 |
0.529 |
|
| 2009 |
Rogers EA, Terekhova D, Zhang HM, Hovis KM, Schwartz I, Marconi RT. Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions. Molecular Microbiology. 71: 1551-73. PMID 19210621 DOI: 10.1111/J.1365-2958.2009.06621.X |
0.767 |
|
| 2009 |
McDowell JV, Huang B, Fenno JC, Marconi RT. Analysis of a unique interaction between the complement regulatory protein factor H and the periodontal pathogen Treponema denticola. Infection and Immunity. 77: 1417-25. PMID 19204088 DOI: 10.1128/Iai.01544-08 |
0.502 |
|
| 2009 |
Meri T, Lehtinen M, McDowell J, Hovis K, Meri S, Seppälä I, Marconi R, Jokiranta T. OspE of Borrelia burgdorferi and FhbA of B. hermsii bind factor H domain 20 via overlapping binding sites Molecular Immunology. 46: 2859. DOI: 10.1016/J.Molimm.2009.05.300 |
0.788 |
|
| 2008 |
Frederick JR, Rogers EA, Marconi RT. Analysis of a growth-phase-regulated two-component regulatory system in the periodontal pathogen Treponema denticola. Journal of Bacteriology. 190: 6162-9. PMID 18621891 DOI: 10.1128/Jb.00046-08 |
0.376 |
|
| 2008 |
Hovis KM, Freedman JC, Zhang H, Forbes JL, Marconi RT. Identification of an antiparallel coiled-coil/loop domain required for ligand binding by the Borrelia hermsii FhbA protein: additional evidence for the role of FhbA in the host-pathogen interaction. Infection and Immunity. 76: 2113-22. PMID 18299341 DOI: 10.1128/Iai.01266-07 |
0.806 |
|
| 2008 |
Caswell CC, Han R, Hovis KM, Ciborowski P, Keene DR, Marconi RT, Lukomski S. The Scl1 protein of M6-type group A Streptococcus binds the human complement regulatory protein, factor H, and inhibits the alternative pathway of complement. Molecular Microbiology. 67: 584-96. PMID 18093091 DOI: 10.1111/J.1365-2958.2007.06067.X |
0.796 |
|
| 2008 |
Hovis KM, Freedman JC, Zhang H, Forbes JL, Marconi RT. Identification of an antiparallel coiled-coil/loop domain required for ligand binding by the Borrelia hermsii FhbA protein: Additional evidence for the role of FhbA in the host-pathogen interaction (Infection and Immunity (2008) 76,5, (2113-2122)) Infection and Immunity. 76: 3358. DOI: 10.1128/IAI.00541-08 |
0.785 |
|
| 2008 |
McDowell J, Huang B, Fenno C, Marconi R. Characterisation of the interaction of the human complement regulatory protein factor H with the periodontitis-associated Treponema denticola: Demonstration of specific digestion of factor H by dentilisin Molecular Immunology. 45: 4171. DOI: 10.1016/J.Molimm.2008.08.228 |
0.437 |
|
| 2007 |
Earnhart CG, Marconi RT. An octavalent lyme disease vaccine induces antibodies that recognize all incorporated OspC type-specific sequences. Human Vaccines. 3: 281-9. PMID 17921702 DOI: 10.4161/Hv.4661 |
0.358 |
|
| 2007 |
Rogers EA, Marconi RT. Delineation of species-specific binding properties of the CspZ protein (BBH06) of Lyme disease spirochetes: evidence for new contributions to the pathogenesis of Borrelia spp. Infection and Immunity. 75: 5272-81. PMID 17846117 DOI: 10.1128/Iai.00850-07 |
0.545 |
|
| 2007 |
Earnhart CG, Marconi RT. OspC phylogenetic analyses support the feasibility of a broadly protective polyvalent chimeric Lyme disease vaccine. Clinical and Vaccine Immunology : Cvi. 14: 628-34. PMID 17360854 DOI: 10.1128/Cvi.00409-06 |
0.331 |
|
| 2007 |
Earnhart CG, Marconi RT. Construction and analysis of variants of a polyvalent Lyme disease vaccine: approaches for improving the immune response to chimeric vaccinogens. Vaccine. 25: 3419-27. PMID 17239505 DOI: 10.1016/J.Vaccine.2006.12.051 |
0.339 |
|
| 2007 |
McDowell JV, Frederick J, Stamm L, Marconi RT. Identification of the gene encoding the FhbB protein of Treponema denticola, a highly unique factor H-like protein 1 binding protein. Infection and Immunity. 75: 1050-4. PMID 17101650 DOI: 10.1128/Iai.01458-06 |
0.558 |
|
| 2007 |
Earnhart CG, Buckles EL, Marconi RT. Development of an OspC-based tetravalent, recombinant, chimeric vaccinogen that elicits bactericidal antibody against diverse Lyme disease spirochete strains. Vaccine. 25: 466-80. PMID 16996663 DOI: 10.1016/J.Vaccine.2006.07.052 |
0.357 |
|
| 2007 |
McDowell JV, Saldon T, Gordon DL, Stamm L, Marconi RT. Analysis of factor H binding by the periodontitis associated spirochete Treponema denticola; identification of FhbB, a unique FHL-1 specific binding protein Molecular Immunology. 44: 214. DOI: 10.1016/J.Molimm.2006.07.157 |
0.527 |
|
| 2007 |
Hovis KM, McDowell JV, Saldon T, Gordon DL, Stamm L, Marconi RT. Microbially produced factor H binding proteins of pathogenic spirochetes: From lyme disease to periodontal disease: Analysis of expression, structure and diverse functional roles Molecular Immunology. 44: 186. DOI: 10.1016/J.Molimm.2006.07.093 |
0.796 |
|
| 2007 |
Hovis KM, Schriefer ME, Sadlon T, Gordon DL, Marconi RT. Molecular and immunological analyses of the Borrelia hermsii factor H/FHL-1 binding protein, FhbA Molecular Immunology. 44: 185. DOI: 10.1016/J.Molimm.2006.07.092 |
0.804 |
|
| 2006 |
Buckles EL, Earnhart CG, Marconi RT. Analysis of antibody response in humans to the type A OspC loop 5 domain and assessment of the potential utility of the loop 5 epitope in Lyme disease vaccine development. Clinical and Vaccine Immunology : Cvi. 13: 1162-5. PMID 17028218 DOI: 10.1128/Cvi.00099-06 |
0.361 |
|
| 2006 |
Hovis KM, Schriefer ME, Bahlani S, Marconi RT. Immunological and molecular analyses of the Borrelia hermsii factor H and factor H-like protein 1 binding protein, FhbA: demonstration of its utility as a diagnostic marker and epidemiological tool for tick-borne relapsing fever. Infection and Immunity. 74: 4519-29. PMID 16861638 DOI: 10.1128/Iai.00377-06 |
0.815 |
|
| 2006 |
McDowell JV, Hovis KM, Zhang H, Tran E, Lankford J, Marconi RT. Evidence that the BBA68 protein (BbCRASP-1) of the Lyme disease spirochetes does not contribute to factor H-mediated immune evasion in humans and other animals. Infection and Immunity. 74: 3030-4. PMID 16622245 DOI: 10.1128/Iai.74.5.3030-3034.2006 |
0.809 |
|
| 2006 |
Hovis KM, Jones JP, Sadlon T, Raval G, Gordon DL, Marconi RT. Molecular analyses of the interaction of Borrelia hermsii FhbA with the complement regulatory proteins factor H and factor H-like protein 1. Infection and Immunity. 74: 2007-14. PMID 16552029 DOI: 10.1128/Iai.74.4.2007-2014.2006 |
0.818 |
|
| 2006 |
Hovis KM, Tran E, Sundy CM, Buckles E, McDowell JV, Marconi RT. Selective binding of Borrelia burgdorferi OspE paralogs to factor H and serum proteins from diverse animals: possible expansion of the role of OspE in Lyme disease pathogenesis. Infection and Immunity. 74: 1967-72. PMID 16495576 DOI: 10.1128/Iai.74.3.1967-1972.2006 |
0.806 |
|
| 2005 |
Earnhart CG, Buckles EL, Dumler JS, Marconi RT. Demonstration of OspC type diversity in invasive human lyme disease isolates and identification of previously uncharacterized epitopes that define the specificity of the OspC murine antibody response. Infection and Immunity. 73: 7869-77. PMID 16299277 DOI: 10.1128/Iai.73.12.7869-7877.2005 |
0.41 |
|
| 2005 |
Zhang H, Marconi RT. Demonstration of cotranscription and 1-methyl-3-nitroso-nitroguanidine induction of a 30-gene operon of Borrelia burgdorferi: evidence that the 32-kilobase circular plasmids are prophages. Journal of Bacteriology. 187: 7985-95. PMID 16291672 DOI: 10.1128/Jb.187.23.7985-7995.2005 |
0.439 |
|
| 2005 |
McDowell JV, Lankford J, Stamm L, Sadlon T, Gordon DL, Marconi RT. Demonstration of factor H-like protein 1 binding to Treponema denticola, a pathogen associated with periodontal disease in humans. Infection and Immunity. 73: 7126-32. PMID 16239506 DOI: 10.1128/Iai.73.11.7126-7132.2005 |
0.55 |
|
| 2005 |
McDowell JV, Harlin ME, Rogers EA, Marconi RT. Putative coiled-coil structural elements of the BBA68 protein of Lyme disease spirochetes are required for formation of its factor H binding site. Journal of Bacteriology. 187: 1317-23. PMID 15687195 DOI: 10.1128/Jb.187.4.1317-1323.2005 |
0.523 |
|
| 2005 |
Zhang H, Raji A, Theisen M, Hansen PR, Marconi RT. bdrF2 of Lyme disease spirochetes is coexpressed with a series of cytoplasmic proteins and is produced specifically during early infection. Journal of Bacteriology. 187: 175-84. PMID 15601701 DOI: 10.1128/Jb.187.1.175-184.2005 |
0.465 |
|
| 2004 |
McDowell JV, Wolfgang J, Senty L, Sundy CM, Noto MJ, Marconi RT. Demonstration of the involvement of outer surface protein E coiled coil structural domains and higher order structural elements in the binding of infection-induced antibody and the complement-regulatory protein, factor H. Journal of Immunology (Baltimore, Md. : 1950). 173: 7471-80. PMID 15585873 DOI: 10.4049/Jimmunol.173.12.7471 |
0.546 |
|
| 2004 |
Hovis KM, McDowell JV, Griffin L, Marconi RT. Identification and characterization of a linear-plasmid-encoded factor H-binding protein (FhbA) of the relapsing fever spirochete Borrelia hermsii. Journal of Bacteriology. 186: 2612-8. PMID 15090501 DOI: 10.1128/Jb.186.9.2612-2618.2004 |
0.818 |
|
| 2003 |
McDowell JV, Tran E, Hamilton D, Wolfgang J, Miller K, Marconi RT. Analysis of the ability of spirochete species associated with relapsing fever, avian borreliosis, and epizootic bovine abortion to bind factor H and cleave c3b. Journal of Clinical Microbiology. 41: 3905-10. PMID 12904415 DOI: 10.1128/Jcm.41.8.3905-3910.2003 |
0.496 |
|
| 2003 |
McDowell JV, Wolfgang J, Tran E, Metts MS, Hamilton D, Marconi RT. Comprehensive analysis of the factor h binding capabilities of borrelia species associated with lyme disease: delineation of two distinct classes of factor h binding proteins. Infection and Immunity. 71: 3597-602. PMID 12761145 DOI: 10.1128/Iai.71.6.3597-3602.2003 |
0.539 |
|
| 2003 |
Metts MS, McDowell JV, Theisen M, Hansen PR, Marconi RT. Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice. Infection and Immunity. 71: 3587-96. PMID 12761144 DOI: 10.1128/Iai.71.6.3587-3596.2003 |
0.531 |
|
| 2002 |
Roberts DM, Caimano M, McDowell J, Theisen M, Holm A, Orff E, Nelson D, Wikel S, Radolf J, Marconi RT. Environmental regulation and differential production of members of the Bdr protein family of Borrelia burgdorferi. Infection and Immunity. 70: 7033-41. PMID 12438383 DOI: 10.1128/Iai.70.12.7033-7041.2002 |
0.381 |
|
| 2002 |
McDowell JV, Sung SY, Hu LT, Marconi RT. Evidence that the variable regions of the central domain of VlsE are antigenic during infection with lyme disease spirochetes. Infection and Immunity. 70: 4196-203. PMID 12117928 DOI: 10.1128/Iai.70.8.4196-4203.2002 |
0.606 |
|
| 2001 |
Sung SY, McDowell JV, Marconi RT. Evidence for the contribution of point mutations to vlsE variation and for apparent constraints on the net accumulation of sequence changes in vlsE during infection with Lyme disease spirochetes. Journal of Bacteriology. 183: 5855-61. PMID 11566983 DOI: 10.1128/Jb.183.20.5855-5861.2001 |
0.561 |
|
| 2001 |
McDowell JV, Sung SY, Price G, Marconi RT. Demonstration of the genetic stability and temporal expression of select members of the lyme disease spirochete OspF protein family during infection in mice. Infection and Immunity. 69: 4831-8. PMID 11447157 DOI: 10.1128/Iai.69.8.4831-4838.2001 |
0.604 |
|
| 2001 |
McDowell JV, Sung SY, Labandeira-Rey M, Skare JT, Marconi RT. Analysis of mechanisms associated with loss of infectivity of clonal populations of Borrelia burgdorferi B31MI. Infection and Immunity. 69: 3670-7. PMID 11349029 DOI: 10.1128/Iai.69.6.3670-3677.2001 |
0.546 |
|
| 2000 |
Roberts DM, Theisen M, Marconi RT. Analysis of the cellular localization of Bdr paralogs in Borrelia burgdorferi, a causative agent of lyme disease: Evidence for functional diversity Journal of Bacteriology. 182: 4222-4226. PMID 10894730 DOI: 10.1128/Jb.182.15.4222-4226.2000 |
0.43 |
|
| 2000 |
Roberts DM, Carlyon JA, Theisen M, Marconi RT. The bdr gene families of the Lyme disease and relapsing fever spirochetes: Potential influence on biology, pathogenesis, and evolution Emerging Infectious Diseases. 6: 110-122. PMID 10756144 DOI: 10.3201/Eid0602.000203 |
0.393 |
|
| 2000 |
Carlyon JA, Roberts DM, Theisen M, Sadler C, Marconi RT. Molecular and immunological analyses of the Borrelia turicatae Bdr protein family Infection and Immunity. 68: 2369-2373. PMID 10722647 DOI: 10.1128/Iai.68.4.2369-2373.2000 |
0.404 |
|
| 2000 |
Sung SY, McDowell JV, Carlyon JA, Marconi RT. Mutation and recombination in the upstream homology box-flanked ospE-related genes of the Lyme disease spirochetes result in the development of new antigenic variants during infection. Infection and Immunity. 68: 1319-27. PMID 10678944 DOI: 10.1128/Iai.68.3.1319-1327.2000 |
0.619 |
|
| 2000 |
Carlyon JF, Roberts DM, Marconi RT. Evolutionary and molecular analyses of the Borrelia bdr super gene family: Delineation of distinct sub-families and demonstration of the genus wide conservation of putative functional domains, structural properties and repeat motifs Microbial Pathogenesis. 28: 89-105. PMID 10644495 DOI: 10.1006/Mpat.1999.0326 |
0.407 |
|
| 1999 |
Marconi RT, Hohenberger S, Jauris-Heipke S, Schulte-Spechtel U, LaVoie CP, Rößler D, Wilske B. Genetic analysis of Borrelia garinii OspA serotype 4 strains associated with neuroborreliosis: Evidence for extensive genetic homogeneity Journal of Clinical Microbiology. 37: 3965-3970. PMID 10565915 DOI: 10.1128/Jcm.37.12.3965-3970.1999 |
0.335 |
|
| 1998 |
Sung SY, Lavoie CP, Carlyon JA, Marconi RT. Genetic divergence and evolutionary instability in ospE-related members of the upstream homology box gene family in Borrelia burgdorferi sensu lato complex isolates. Infection and Immunity. 66: 4656-68. PMID 9746562 DOI: 10.1128/Iai.66.10.4656-4668.1998 |
0.578 |
|
| 1998 |
Carlyon JA, Marconi RT. Cloning and molecular characterization of a multicopy, linear plasmid- carried, repeat motif-containing gene from Borrelia turicatae, a causative agent of relapsing fever Journal of Bacteriology. 180: 4974-4981. PMID 9733706 DOI: 10.1128/Jb.180.18.4974-4981.1998 |
0.441 |
|
| 1998 |
Carlyon JA, LaVoie C, Sung SY, Marconi RT. Analysis of the organization of multicopy linear- and circular-plasmid-carried open reading frames in Borrelia burgdorferi sensu lato isolates. Infection and Immunity. 66: 1149-58. PMID 9488408 DOI: 10.1128/Iai.66.3.1149-1158.1998 |
0.544 |
|
| 1997 |
Cloud JL, Marconi RT, Eggers CH, Garon CF, Tilly K, Samuels DS. Cloning and expression of the Borrelia burgdorferi lon gene Gene. 194: 137-141. PMID 9266683 DOI: 10.1016/S0378-1119(97)00196-0 |
0.352 |
|
| 1996 |
Marconi RT, Sung SY, Hughes CA, Carlyon JA. Molecular and evolutionary analyses of a variable series of genes in Borrelia burgdorferi that are related to ospE and ospF, constitute a gene family, and share a common upstream homology box. Journal of Bacteriology. 178: 5615-26. PMID 8824605 DOI: 10.1128/Jb.178.19.5615-5626.1996 |
0.556 |
|
| 1995 |
Marconi RT, Liveris D, Schwartz I. Identification of novel insertion elements, restriction fragment length polymorphism patterns, and discontinuous 23S rRNA in Lyme disease spirochetes: Phylogenetic analyses of rRNA genes and their intergenic spacers in Borrelia japonica sp. nov. and genomic group 21038 (Borrelia andersonii sp. nov.) isolates Journal of Clinical Microbiology. 33: 2427-2434. PMID 7494041 DOI: 10.1128/Jcm.33.9.2427-2434.1995 |
0.322 |
|
| 1994 |
Konkel ME, Marconi RT, Mead DJ, Cieplak W. Cloning and expression of the hup gene encoding a histone-like protein of Campylobacter jejuni Gene. 146: 83-86. PMID 8063109 DOI: 10.1016/0378-1119(94)90837-0 |
0.323 |
|
| 1990 |
Marconi RT, Lodmell JS, Hill WE. Identification of a rRNA/chloramphenicol interaction site within the peptidyltransferase center of the 50 S subunit of the Escherichia coli ribosome. The Journal of Biological Chemistry. 265: 7894-9. PMID 1692317 |
0.302 |
|
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