| Year |
Citation |
Score |
| 2025 |
Van Eyndhoven LC, Kinsler G, Zhang J, O'Farrell A, Abderrahim R, Srivastav A, Triandafillou CG, Greco TM, Zaret KS, Cristea IM, Orzalli MH, Drayman N, Singh A, Raj A. Lineage memory shapes viral resistance barriers in human skin. Biorxiv : the Preprint Server For Biology. PMID 40666908 DOI: 10.1101/2025.06.27.661951 |
0.307 |
|
| 2024 |
Parameswaran P, Payne L, Powers J, Rashighi M, Orzalli MH. A viral E3 ubiquitin ligase produced by herpes simplex virus 1 inhibits the NLRP1 inflammasome. The Journal of Experimental Medicine. 221. PMID 38861480 DOI: 10.1084/jem.20231518 |
0.476 |
|
| 2023 |
Broekema N, Mertens ME, Angelova M, Orzalli MH, Oh HS, Knipe DM. Herpes simplex virus infected cell protein 8 is required for viral inhibition of the cGAS pathway. Virology. 585: 34-41. PMID 37271042 DOI: 10.1016/j.virol.2023.05.002 |
0.689 |
|
| 2022 |
Orzalli MH, Parameswaran P. Effector-triggered immunity in mammalian antiviral defense. Trends in Immunology. 43: 1006-1017. PMID 36369102 DOI: 10.1016/j.it.2022.10.004 |
0.544 |
|
| 2022 |
Maeda K, Zachos NC, Orzalli MH, Schmieder SS, Chang D, Gwilt KB, Doucet M, Baetz NW, Lee S, Crawford SE, Estes MK, Kagan JC, Turner JR, Lencer WI. Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces. Cell Host & Microbe. 30: 216-231.e5. PMID 35143768 DOI: 10.1016/j.chom.2021.12.011 |
0.328 |
|
| 2021 |
Orzalli MH, Prochera A, Payne L, Smith A, Garlick JA, Kagan JC. Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells. Immunity. PMID 33979579 DOI: 10.1016/j.immuni.2021.04.012 |
0.434 |
|
| 2019 |
de Oliveira Mann CC, Orzalli MH, King DS, Kagan JC, Lee ASY, Kranzusch PJ. Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation. Cell Reports. 27: 1165-1175.e5. PMID 31018131 DOI: 10.1016/J.Celrep.2019.03.098 |
0.451 |
|
| 2019 |
Orzalli MH. Human Skin Explants Recapitulate Key Features of HSV-1 Infections. The Journal of Investigative Dermatology. 139: 519-521. PMID 30797319 DOI: 10.1016/J.Jid.2018.09.015 |
0.384 |
|
| 2018 |
Orzalli MH, Smith A, Jurado KA, Iwasaki A, Garlick JA, Kagan JC. An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication. Molecular Cell. PMID 30100266 DOI: 10.1016/J.Molcel.2018.07.009 |
0.492 |
|
| 2018 |
Merkl PE, Orzalli M, Knipe DM. Mechanisms of Host IFI16, PML and Daxx Protein Restriction of Herpes Simplex Virus 1 Replication. Journal of Virology. PMID 29491153 DOI: 10.1128/Jvi.00057-18 |
0.678 |
|
| 2017 |
Orzalli MH, Kagan JC. Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection. Trends in Cell Biology. PMID 28642032 DOI: 10.1016/J.Tcb.2017.05.007 |
0.578 |
|
| 2017 |
Kurt-Jones EA, Orzalli MH, Knipe DM. Innate Immune Mechanisms and Herpes Simplex Virus Infection and Disease. Advances in Anatomy, Embryology, and Cell Biology. 223: 49-75. PMID 28528439 DOI: 10.1007/978-3-319-53168-7_3 |
0.624 |
|
| 2016 |
Orzalli MH, Kagan JC. A one-protein signaling pathway in the innate immune system. Science Immunology. 1: eaah6184. PMID 28783697 DOI: 10.1126/Sciimmunol.Aah6184 |
0.329 |
|
| 2016 |
Orzalli MH, Broekema NM, Knipe DM. Varying Roles of Herpes Simplex Virus 1 ICP0 and Vhs in Loss of Cellular IFI16 in Different Cell Types. Journal of Virology. PMID 27412599 DOI: 10.1128/Jvi.00939-16 |
0.577 |
|
| 2015 |
Orzalli MH, Broekema NM, Diner BA, Hancks DC, Elde NC, Cristea IM, Knipe DM. cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection. Proceedings of the National Academy of Sciences of the United States of America. 112: E1773-81. PMID 25831530 DOI: 10.1073/Pnas.1424637112 |
0.709 |
|
| 2014 |
Orzalli MH, Knipe DM. Cellular sensing of viral DNA and viral evasion mechanisms. Annual Review of Microbiology. 68: 477-92. PMID 25002095 DOI: 10.1146/Annurev-Micro-091313-103409 |
0.683 |
|
| 2014 |
Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC. A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction. Cell. 156: 705-16. PMID 24529375 DOI: 10.1016/J.Cell.2014.01.019 |
0.548 |
|
| 2013 |
Orzalli MH, Conwell SE, Berrios C, DeCaprio JA, Knipe DM. Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA. Proceedings of the National Academy of Sciences of the United States of America. 110: E4492-501. PMID 24198334 DOI: 10.1073/Pnas.1316194110 |
0.7 |
|
| 2013 |
Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nature Immunology. 14: 179-85. PMID 23263557 DOI: 10.1038/Ni.2509 |
0.67 |
|
| 2012 |
Orzalli MH, DeLuca NA, Knipe DM. Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein. Proceedings of the National Academy of Sciences of the United States of America. 109: E3008-17. PMID 23027953 DOI: 10.1073/Pnas.1211302109 |
0.691 |
|
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