Caitrin W. McDonough, Ph.D. - Publications

Affiliations: 
2010 Wake Forest University, Winston-Salem, NC, United States 
Area:
Genetics, Endocrinology Biology

44/99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Thomas CD, Franchi F, Rossi JS, Keeley EC, Anderson RD, Beitelshees AL, Duarte JD, Ortega-Paz L, Gong Y, Kerensky RA, Kulick N, McDonough CW, Nguyen AB, Wang Y, Winget M, et al. Effectiveness of Clopidogrel vs Alternative P2Y Inhibitors Based on the ABCD-GENE Score. Journal of the American College of Cardiology. 83: 1370-1381. PMID 38599713 DOI: 10.1016/j.jacc.2024.02.015  0.344
2023 Armstrong ND, Srinivasasainagendra V, Ammous F, Assimes TL, Beitelshees AL, Brody J, Cade BE, Ida Chen YD, Chen H, de Vries PS, Floyd JS, Franceschini N, Guo X, Hellwege JN, House JS, ... ... McDonough CW, et al. Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program. Frontiers in Genetics. 14: 1278215. PMID 38162683 DOI: 10.3389/fgene.2023.1278215  0.659
2022 Armstrong ND, Srinivasasainagendra V, Chekka LMS, Nguyen NHK, Nahid NA, Jones AC, Tanner RM, Hidalgo BA, Limdi NA, Claas SA, Gong Y, McDonough CW, Cooper-DeHoff RM, Johnson JA, Tiwari HK, et al. Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study. Genes. 13. PMID 35886043 DOI: 10.3390/genes13071260  0.331
2021 Guerra LA, Lteif C, Arwood MJ, McDonough CW, Dumeny L, Desai AA, Cavallari LH, Duarte JD. Genetic polymorphisms in ADRB2 and ADRB1 are associated with differential survival in heart failure patients taking β-blockers. The Pharmacogenomics Journal. PMID 34642472 DOI: 10.1038/s41397-021-00257-1  0.355
2021 Yang G, Singh S, McDonough CW, Lamba JK, Hamadeh I, Shannon Holliday L, Wang D, Katz J, Lakatos PA, Balla B, Kosa JP, Andrea Pelliccioni G, Price DK, Van Driest SL, Figg WD, et al. Genome-wide Association Study Identified Chromosome 8 Locus Associated with Medication-related Osteonecrosis of the Jaw. Clinical Pharmacology and Therapeutics. PMID 34390503 DOI: 10.1002/cpt.2397  0.456
2021 McDonough CW, Warren HR, Jack JR, Motsinger-Reif AA, Armstrong ND, Bis JC, House JS, Singh S, El Rouby NM, Gong Y, Mychaleckyj JC, Rotroff DM, Benavente OR, Caulfield MJ, Doria A, et al. Adverse Cardiovascular Outcomes and Antihypertensive treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies (ICAPS). Clinical Pharmacology and Therapeutics. PMID 34231218 DOI: 10.1002/cpt.2355  0.417
2020 Yang G, Collins JM, Rafiee R, Singh S, Langaee T, McDonough CW, Holliday LS, Wang D, Lamba J, Kim YS, Pelliccioni GA, Vaszilko M, Kosa JP, Balla B, Lakatos PA, et al. SIRT1 Gene SNP rs932658 is Associated with Medication-Related Osteonecrosis of the Jaw. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32967053 DOI: 10.1002/jbmr.4185  0.483
2019 Singh S, McDonough CW, Gong Y, Bailey KR, Boerwinkle E, Chapman AB, Gums JG, Turner ST, Cooper-DeHoff RM, Johnson JA. Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response. Scientific Reports. 9: 17323. PMID 31754133 DOI: 10.1038/S41598-019-53345-5  0.417
2019 Singh S, Warren HR, Hiltunen TP, McDonough CW, El Rouby N, Salvi E, Wang Z, Garofalidou T, Fyhrquist F, Kontula KK, Glorioso V, Zaninello R, Glorioso N, Pepine CJ, Munroe PB, et al. Genome-Wide Meta-Analysis of Blood Pressure Response to β-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies). Journal of the American Heart Association. 8: e013115. PMID 31423876 DOI: 10.1161/Jaha.119.013115  0.376
2019 Singh S, El Rouby N, McDonough CW, Gong Y, Bailey KR, Boerwinkle E, Chapman AB, Gums JG, Turner ST, Cooper-DeHoff RM, Johnson JA. Genomic Association Analysis Reveals Variants Associated with Blood Pressure Response to Beta-Blockers in European Americans. Clinical and Translational Science. PMID 31033190 DOI: 10.1111/Cts.12643  0.408
2019 Yang G, Singh S, Chen Y, Hamadeh IS, Langaee T, McDonough CW, Holliday LS, Lamba J, Moreb JS, Katz J, Gong Y. Pharmacogenomics of osteonecrosis of the jaw. Bone. PMID 31022475 DOI: 10.1016/J.Bone.2019.04.010  0.495
2018 Singh S, Wang Z, Shahin MH, Langaee TY, Gong Y, Turner ST, Chapman AB, Gums JG, McDonough CW, Bailey KR, Beitelshees AL, Cooper-DeHoff RM, Scherer S, Boerwinkle E, Johnson JA. Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide. Pharmacogenetics and Genomics. PMID 30289819 DOI: 10.1097/Fpc.0000000000000353  0.332
2018 El Rouby N, McDonough CW, Gong Y, McClure LA, Mitchell BD, Horenstein RB, Talbert RL, Crawford DC, Gitzendanner MA, Takahashi A, Tanaka T, Kubo M, Pepine CJ, Cooper-DeHoff RM, et al. Genome-wide association analysis of common genetic variants of resistant hypertension. The Pharmacogenomics Journal. PMID 30237584 DOI: 10.1038/S41397-018-0049-X  0.433
2018 McDonough CW, Magvanjav O, Sá ACC, El Rouby NM, Dave C, Deitchman AN, Kawaguchi-Suzuki M, Mei W, Shen Y, Singh RSP, Solayman M, Bailey KR, Boerwinkle E, Chapman AB, Gums JG, et al. Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses). Circulation. Genomic and Precision Medicine. 11: e001854. PMID 29650764 DOI: 10.1161/CIRCGEN.117.001854  0.324
2018 Singh S, McDonough CW, Gong Y, Alghamdi WA, Arwood MJ, Bargal SA, Dumeny L, Li WY, Mehanna M, Stockard B, Yang G, de Oliveira FA, Fredette NC, Shahin MH, Bailey KR, et al. Genome Wide Association Study Identifies theLocus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients. Journal of the American Heart Association. 7. PMID 29523524 DOI: 10.1161/Jaha.117.007339  0.42
2016 de Oliveira FA, Shahin MH, Gong Y, McDonough CW, Beitelshees AL, Gums JG, Chapman AB, Boerwinkle E, Turner ST, Frye RF, Fiehn O, Kaddurah-Daouk R, Johnson JA, Cooper-DeHoff RM. Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach. Metabolomics : Open Access. 12. PMID 28217400 DOI: 10.1007/S11306-016-1076-8  0.367
2016 Salvi E, Wang Z, Rizzi F, Gong Y, McDonough CW, Padmanabhan S, Hiltunen TP, Lanzani C, Zaninello R, Chittani M, Bailey KR, Sarin AP, Barcella M, Melander O, Chapman AB, et al. Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide. Hypertension (Dallas, Tex. : 1979). PMID 27802415 DOI: 10.1161/Hypertensionaha.116.08267  0.33
2016 Chang SW, McDonough CW, Gong Y, Johnson TA, Tsunoda T, Gamazon ER, Perera MA, Takahashi A, Tanaka T, Kubo M, Pepine CJ, Johnson JA, Cooper-DeHoff RM. Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes. The Pharmacogenomics Journal. PMID 27670767 DOI: 10.1038/tpj.2016.67  0.517
2016 Shahin MH, Gong Y, McDonough CW, Rotroff DM, Beitelshees AL, Garrett TJ, Gums JG, Motsinger-Reif A, Chapman AB, Turner ST, Boerwinkle E, Frye RF, Fiehn O, Cooper-DeHoff RM, Kaddurah-Daouk R, et al. A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration. Hypertension. PMID 27381900 DOI: 10.1161/Hypertensionaha.116.07328  0.371
2016 Gong Y, Wang Z, Beitelshees AL, McDonough CW, Langaee TY, Hall K, Schmidt SO, Curry RW, Gums JG, Bailey KR, Boerwinkle E, Chapman AB, Turner ST, Cooper-DeHoff RM, Johnson JA. Pharmacogenomic Genome-Wide Meta-Analysis of Blood Pressure Response to β-Blockers in Hypertensive African Americans. Hypertension. PMID 26729753 DOI: 10.1161/Hypertensionaha.115.06345  0.399
2016 de Oliveira FA, Shahin MH, Gong Y, McDonough CW, Beitelshees AL, Gums JG, Chapman AB, Boerwinkle E, Turner ST, Frye RF, Fiehn O, Kaddurah-Daouk R, Johnson JA, Cooper-DeHoff RM. Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach Metabolomics. 12. DOI: 10.1007/s11306-016-1076-8  0.339
2015 Hoh BL, Gong Y, McDonough CW, Waters MF, Royster AJ, Sheehan TO, Burkley B, Langaee TY, Mocco J, Zuckerman SL, Mummareddy N, Stephens ML, Ingram C, Shaffer CM, Denny JC, et al. CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease. Journal of Neurosurgery. 1-6. PMID 26587656 DOI: 10.3171/2015.6.Jns15795  0.399
2014 Fontana V, McDonough CW, Gong Y, El Rouby NM, Sá AC, Taylor KD, Chen YD, Gums JG, Chapman AB, Turner ST, Pepine CJ, Johnson JA, Cooper-DeHoff RM. Large-scale gene-centric analysis identifies polymorphisms for resistant hypertension. Journal of the American Heart Association. 3: e001398. PMID 25385345 DOI: 10.1161/JAHA.114.001398  0.492
2014 Vandell AG, McDonough CW, Gong Y, Langaee TY, Lucas AM, Chapman AB, Gums JG, Beitelshees AL, Bailey KR, Johnson RJ, Boerwinkle E, Turner ST, Cooper-DeHoff RM, Johnson JA. Hydrochlorothiazide-induced hyperuricaemia in the pharmacogenomic evaluation of antihypertensive responses study. Journal of Internal Medicine. 276: 486-97. PMID 24612202 DOI: 10.1111/Joim.12215  0.404
2014 Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, ... ... McDonough CW, et al. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics. 94: 349-60. PMID 24560520 DOI: 10.1016/J.Ajhg.2013.12.016  0.337
2014 Yoneyama S, Guo Y, Lanktree MB, Barnes MR, Elbers CC, Karczewski KJ, Padmanabhan S, Bauer F, Baumert J, Beitelshees A, Berenson GS, Boer JM, Burke G, Cade B, Chen W, ... ... McDonough C, et al. Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Human Molecular Genetics. 23: 2498-510. PMID 24345515 DOI: 10.1093/Hmg/Ddt626  0.419
2014 Gong Y, McDonough CW, Beitelshees AL, Karnes JH, O'Connell JR, Turner ST, Chapman AB, Gums JG, Bailey KR, Boerwinkle E, Johnson JA, Cooper-DeHoff RM. PROX1 gene variant is associated with fasting glucose change after antihypertensive treatment. Pharmacotherapy. 34: 123-30. PMID 24122840 DOI: 10.1002/Phar.1355  0.458
2013 Karnes JH, Gong Y, Pacanowski MA, McDonough CW, Arwood MJ, Langaee TY, Pepine CJ, Johnson JA, Cooper-Dehoff RM. Impact of TCF7L2 single nucleotide polymorphisms on hydrochlorothiazide-induced diabetes. Pharmacogenetics and Genomics. 23: 697-705. PMID 24128935 DOI: 10.1097/FPC.0000000000000012  0.631
2013 McDonough CW, Gillis NK, Alsultan A, Chang SW, Kawaguchi-Suzuki M, Lang JE, Shahin MH, Buford TW, El Rouby NM, Sá AC, Langaee TY, Gums JG, Chapman AB, Cooper-DeHoff RM, Turner ST, et al. Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study. Plos One. 8: e76984. PMID 24116192 DOI: 10.1371/Journal.Pone.0076984  0.383
2013 Turner ST, Boerwinkle E, O'Connell JR, Bailey KR, Gong Y, Chapman AB, McDonough CW, Beitelshees AL, Schwartz GL, Gums JG, Padmanabhan S, Hiltunen TP, Citterio L, Donner KM, Hedner T, et al. Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide. Hypertension. 62: 391-7. PMID 23753411 DOI: 10.1161/Hypertensionaha.111.00436  0.384
2013 McDonough CW, Gong Y, Padmanabhan S, Burkley B, Langaee TY, Melander O, Pepine CJ, Dominiczak AF, Cooper-Dehoff RM, Johnson JA. Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes. Hypertension. 62: 48-54. PMID 23690342 DOI: 10.1161/HYPERTENSIONAHA.111.00823  0.412
2013 McDonough CW, Burbage SE, Duarte JD, Gong Y, Langaee TY, Turner ST, Gums JG, Chapman AB, Bailey KR, Beitelshees AL, Boerwinkle E, Pepine CJ, Cooper-DeHoff RM, Johnson JA. Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics. Journal of Hypertension. 31: 698-704. PMID 23353631 DOI: 10.1097/Hjh.0B013E32835E2A71  0.334
2013 Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, ... ... McDonough CW, et al. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics. 22: 1663-78. PMID 23303523 DOI: 10.1093/Hmg/Dds555  0.463
2013 Karnes JH, Langaee TY, McDonough CW, Chang SW, Ramos M, Catlin JR, Casanova OE, Gong Y, Pepine CJ, Johnson JA, Cooper-Dehoff RM. Lack of association of the HMGA1 IVS5-13insC variant with type 2 diabetes in an ethnically diverse hypertensive case control cohort. Journal of Translational Medicine. 11: 12. PMID 23302499 DOI: 10.1186/1479-5876-11-12  0.626
2013 Karnes JH, McDonough CW, Gong Y, Vo TT, Langaee TY, Chapman AB, Gums JG, Beitelshees AL, Bailey KR, Del-Aguila JL, Boerwinkle EA, Pepine CJ, Turner ST, Johnson JA, Cooper-DeHoff RM. Association of KCNJ1 variation with change in fasting glucose and new onset diabetes during HCTZ treatment. The Pharmacogenomics Journal. 13: 430-6. PMID 22907731 DOI: 10.1038/Tpj.2012.34  0.547
2012 Gong Y, McDonough CW, Wang Z, Hou W, Cooper-DeHoff RM, Langaee TY, Beitelshees AL, Chapman AB, Gums JG, Bailey KR, Boerwinkle E, Turner ST, Johnson JA. Hypertension susceptibility loci and blood pressure response to antihypertensives: results from the pharmacogenomic evaluation of antihypertensive responses study. Circulation. Cardiovascular Genetics. 5: 686-91. PMID 23087401 DOI: 10.1161/Circgenetics.112.964080  0.387
2012 Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, Ferrara A, et al. A genome-wide association search for type 2 diabetes genes in African Americans. Plos One. 7: e29202. PMID 22238593 DOI: 10.1371/Journal.Pone.0029202  0.568
2011 Freedman BI, Langefeld CD, Lu L, Divers J, Comeau ME, Kopp JB, Winkler CA, Nelson GW, Johnson RC, Palmer ND, Hicks PJ, Bostrom MA, Cooke JN, McDonough CW, Bowden DW. Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans. Plos Genetics. 7: e1002150. PMID 21698141 DOI: 10.1371/Journal.Pgen.1002150  0.776
2011 Murea M, Lu L, Ma L, Hicks PJ, Divers J, McDonough CW, Langefeld CD, Bowden DW, Freedman BI. Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. American Journal of Nephrology. 33: 502-9. PMID 21546767 DOI: 10.1159/000327985  0.725
2011 McDonough CW, Palmer ND, Hicks PJ, Roh BH, An SS, Cooke JN, Hester JM, Wing MR, Bostrom MA, Rudock ME, Lewis JP, Talbert ME, Blevins RA, Lu L, Ng MC, et al. A genome-wide association study for diabetic nephropathy genes in African Americans. Kidney International. 79: 563-72. PMID 21150874 DOI: 10.1038/Ki.2010.467  0.563
2011 Anderson AH, Chen J, Gadebegku CA, Feldman HI, Fink JC, Go AS, Joffe M, Nessel LA, Ojo A, Rader DJ, Reilly MP, Teal V, Teff K, Wright JT, Xie D, ... ... McDonough CW, et al. Contents Vol. 33, 2011 American Journal of Nephrology. 33. DOI: 10.1159/000329531  0.389
2009 McDonough CW, Bostrom MA, Lu L, Hicks PJ, Langefeld CD, Divers J, Mychaleckyj JC, Freedman BI, Bowden DW. Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping. Human Genetics. 126: 805-17. PMID 19690890 DOI: 10.1007/S00439-009-0732-8  0.758
2009 McDonough CW, Hicks PJ, Lu L, Langefeld CD, Freedman BI, Bowden DW. The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-Americans. Human Genetics. 126: 265-75. PMID 19373489 DOI: 10.1007/S00439-009-0667-0  0.761
2007 Freedman BI, Hicks PJ, Sale MM, Pierson ED, Langefeld CD, Rich SS, Xu J, McDonough C, Janssen B, Yard BA, van der Woude FJ, Bowden DW. A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 22: 1131-5. PMID 17205963 DOI: 10.1093/Ndt/Gfl717  0.676
Low-probability matches (unlikely to be authored by this person)
2017 Dumitrescu L, Ritchie MD, Denny JC, El Rouby NM, McDonough CW, Bradford Y, Ramirez AH, Bielinski SJ, Basford MA, Chai HS, Peissig P, Carrell D, Pathak J, Rasmussen LV, Wang X, et al. Genome-wide study of resistant hypertension identified from electronic health records. Plos One. 12: e0171745. PMID 28222112 DOI: 10.1371/Journal.Pone.0171745  0.299
2012 Asselbergs FW, Guo Y, van Iperen EP, Sivapalaratnam S, Tragante V, Lanktree MB, Lange LA, Almoguera B, Appelman YE, Barnard J, Baumert J, Beitelshees AL, Bhangale TR, Chen YD, Gaunt TR, ... ... McDonough CW, et al. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American Journal of Human Genetics. 91: 823-38. PMID 23063622 DOI: 10.1016/J.Ajhg.2012.08.032  0.287
2015 Gong Y, McDonough CW, Beitelshees AL, Rouby NE, Hiltunen TP, O'Connell JR, Padmanabhan S, Langaee TY, Hall K, Schmidt SO, Curry RW, Gums JG, Donner KM, Kontula KK, Bailey KR, et al. PTPRD gene associated with blood pressure response to atenolol and resistant hypertension. Journal of Hypertension. 33: 2278-85. PMID 26425837 DOI: 10.1097/Hjh.0000000000000714  0.276
2015 Langaee TY, Zhong G, Li W, Hamadeh I, Solayman MH, McDonough CW, Stacpoole PW, James MO. The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression. Pharmacogenetics and Genomics. 25: 239-45. PMID 25738370 DOI: 10.1097/FPC.0000000000000129  0.262
2017 Magvanjav O, McDonough CW, Gong Y, McClure LA, Talbert RL, Horenstein RB, Shuldiner AR, Benavente OR, Mitchell BD, Johnson JA. Pharmacogenetic Associations of β1-Adrenergic Receptor Polymorphisms With Cardiovascular Outcomes in the SPS3 Trial (Secondary Prevention of Small Subcortical Strokes). Stroke. PMID 28351962 DOI: 10.1161/Strokeaha.116.015936  0.231
2021 Mehanna M, McDonough CW, Smith SM, Gong Y, Gums JG, Chapman AB, Johnson JA, McIntyre L, Cooper-DeHoff RM. Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients. Metabolites. 11. PMID 34564461 DOI: 10.3390/metabo11090645  0.218
2017 Shahin MH, Sá AC, Webb A, Gong Y, Langaee T, McDonough CW, Riva A, Beitleshees AL, Chapman AB, Gums JG, Turner ST, Boerwinkle E, Scherer SE, Sadee W, Cooper-DeHoff RM, et al. Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response. Circulation. Cardiovascular Genetics. 10. PMID 28115488 DOI: 10.1161/Circgenetics.116.001404  0.217
2017 Sá ACC, Webb A, Gong Y, McDonough CW, Datta S, Langaee TY, Turner ST, Beitelshees AL, Chapman AB, Boerwinkle E, Gums JG, Scherer SE, Cooper-DeHoff RM, Sadee W, Johnson JA. Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics. Scientific Reports. 7: 16068. PMID 29167564 DOI: 10.1038/S41598-017-16343-Z  0.207
2022 Cavallari LH, Limdi NA, Beitelshees AL, Lee JC, Duarte JD, Franchi F, Tuteja S, Giri J, Empey PE, Kreutz RP, Skaar TC, Allen JM, Coons JC, Gong Y, McDonough CW, et al. Evaluation of Potential Racial Disparities in CYP2C19-Guided P2Y Inhibitor Prescribing after Percutaneous Coronary Intervention. Clinical Pharmacology and Therapeutics. PMID 36306392 DOI: 10.1002/cpt.2776  0.207
2022 Thomas CD, Franchi F, Keeley EC, Rossi JS, Winget M, Anderson RD, Dempsey AL, Gong Y, Gower MN, Kerensky RA, Kulick N, Malave JG, McDonough CW, Mulrenin IR, Starostik P, et al. Impact of the ABCD-GENE Score on Clopidogrel Clinical Effectiveness after PCI: A Multi-site, Real-world Investigation. Clinical Pharmacology and Therapeutics. PMID 35429163 DOI: 10.1002/cpt.2612  0.201
2017 Orlando LA, Sperber NR, Voils C, Nichols M, Myers RA, Wu RR, Rakhra-Burris T, Levy KD, Levy M, Pollin TI, Guan Y, Horowitz CR, Ramos M, Kimmel SE, McDonough CW, et al. Developing a common framework for evaluating the implementation of genomic medicine interventions in clinical care: the IGNITE Network's Common Measures Working Group. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 28914267 DOI: 10.1038/Gim.2017.144  0.195
2018 Magvanjav O, Cooper-DeHoff RM, McDonough CW, Gong Y, Segal MS, Hogan WR, Johnson JA. Antihypertensive therapy prescribing patterns and correlates of blood pressure control among hypertensive patients with chronic kidney disease. Journal of Clinical Hypertension (Greenwich, Conn.). PMID 30427124 DOI: 10.1111/jch.13429  0.174
2017 Magvanjav O, Gong Y, McDonough CW, Chapman AB, Turner ST, Gums JG, Bailey KR, Boerwinkle E, Beitelshees AL, Tanaka T, Kubo M, Pepine CJ, Cooper-DeHoff RM, Johnson JA. Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials. Journal of the American Heart Association. 6. PMID 29097388 DOI: 10.1161/Jaha.117.006522  0.172
2016 Weitzel KW, McDonough CW, Elsey AR, Burkley B, Cavallari LH, Johnson JA. Effects of Using Personal Genotype Data on Student Learning and Attitudes in a Pharmacogenomics Course. American Journal of Pharmaceutical Education. 80: 122. PMID 27756930 DOI: 10.5688/ajpe807122  0.166
2018 Sá ACC, Webb A, Gong Y, McDonough CW, Shahin MH, Datta S, Langaee TY, Turner ST, Beitelshees AL, Chapman AB, Boerwinkle E, Gums JG, Scherer SE, Cooper-DeHoff RM, Sadee W, et al. Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies. Bmc Medical Genomics. 11: 55. PMID 29925376 DOI: 10.1186/S12920-018-0370-X  0.166
2019 Orlando LA, Voils C, Horowitz CR, Myers RA, Arwood MJ, Cicali EJ, McDonough CW, Pollin TI, Guan Y, Levy KD, Ramirez A, Quittner A, Madden EB. IGNITE network: Response of patients to genomic medicine interventions. Molecular Genetics & Genomic Medicine. e636. PMID 30895746 DOI: 10.1002/Mgg3.636  0.164
2017 McDonough CW, Hogan WR, Shenkman B, Cooper-DeHoff RM. 2246 Journal of Clinical and Translational Science. 1: 13-13. DOI: 10.1017/cts.2017.63  0.16
2013 Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YPC, Elbers CC, Farrall M, Fischer ME, Gaunt NF, ... ... McDonough CW, et al. Loci influencing blood pressure identified using a cardiovascular gene-centric array Human Molecular Genetics. 22: 3394-3395. DOI: 10.1093/Hmg/Ddt177  0.16
2020 Lee CR, Thomas CD, Beitelshees AL, Tuteja S, Empey PE, Lee JC, Limdi NA, Duarte JD, Skaar TC, Chen Y, Cook KJ, Coons JC, Dillon C, Franchi F, Giri J, ... ... McDonough CW, et al. Impact of the CYP2C19*17 allele on outcomes in patients receiving genotype-guided antiplatelet therapy after percutaneous coronary intervention. Clinical Pharmacology and Therapeutics. PMID 32897581 DOI: 10.1002/Cpt.2039  0.157
2017 Mehanna M, Gong Y, McDonough CW, Beitelshees AL, Gums JG, Chapman AB, Schwartz GL, Johnson JA, Turner ST, Cooper-DeHoff RM. Blood pressure response to metoprolol and chlorthalidone in European and African Americans with hypertension. Journal of Clinical Hypertension (Greenwich, Conn.). PMID 28940643 DOI: 10.1111/jch.13094  0.154
2018 Weitzel KW, Smith DM, Elsey AR, Duong BQ, Burkley B, Clare-Salzler M, Gong Y, Higgins TA, Kong B, Langaee T, McDonough CW, Staley BJ, Vo TT, Wake DT, Cavallari LH, et al. Implementation of Standardized Clinical Processes for TPMT Testing in a Diverse Multidisciplinary Population: Challenges and Lessons Learned. Clinical and Translational Science. PMID 29351371 DOI: 10.1111/cts.12533  0.152
2022 Jaworek T, Xu H, Gaynor BJ, Cole JW, Rannikmae K, Stanne TM, Tomppo L, Abedi V, Amouyel P, Armstrong ND, Attia J, Bell S, Benavente OR, Boncoraglio GB, Butterworth A, ... ... McDonough CW, et al. Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke. Neurology. PMID 36240095 DOI: 10.1212/WNL.0000000000201006  0.15
2021 McDonough CW. Pharmacogenomics in Cardiovascular Diseases. Current Protocols. 1: e189. PMID 34232575 DOI: 10.1002/cpz1.189  0.15
2021 Schunk SJ, Kleber ME, März W, Pang S, Zewinger S, Triem S, Ege P, Reichert MC, Krawczyk M, Weber SN, Jaumann I, Schmit D, Sarakpi T, Wagenpfeil S, Kramann R, ... ... McDonough CW, et al. Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. European Heart Journal. PMID 33748830 DOI: 10.1093/eurheartj/ehab107  0.146
2019 Mehanna M, Wang Z, Gong Y, McDonough CW, Beitelshees AL, Gums JG, Chapman AB, Schwartz GL, Bailey KR, Johnson JA, Turner ST, Cooper-DeHoff RM. Plasma Renin Activity Is a Predictive Biomarker of Blood Pressure Response in European but not in African Americans With Uncomplicated Hypertension. American Journal of Hypertension. PMID 30753254 DOI: 10.1093/Ajh/Hpz022  0.143
2023 Jafari E, Cooper-DeHoff RM, Effron MB, Hogan WR, McDonough CW. Characteristics and Predictors of Apparent Treatment Resistant Hypertension in Real-World Populations Using Electronic Health Record-Based Data. Medrxiv : the Preprint Server For Health Sciences. PMID 37205447 DOI: 10.1101/2023.04.28.23289293  0.134
2023 Jafari E, Cooper-DeHoff RM, Effron MB, Hogan WR, McDonough CW. Characteristics and Predictors of Apparent Treatment Resistant Hypertension in Real-World Populations Using Electronic Health Record-Based Data. American Journal of Hypertension. PMID 37712350 DOI: 10.1093/ajh/hpad084  0.133
2009 Schulze SR, Curio-Penny B, Speese S, Dialynas G, Cryderman DE, McDonough CW, Nalbant D, Petersen M, Budnik V, Geyer PK, Wallrath LL. A comparative study of Drosophila and human A-type lamins. Plos One. 4: e7564. PMID 19855837 DOI: 10.1371/Journal.Pone.0007564  0.133
2022 Mehanna M, McDonough CW, Smith SM, Gong Y, Gums JG, Chapman AB, Johnson JA, Cooper-DeHoff RM. Influence of Genetic West African Ancestry on Metabolomics among Hypertensive Patients. Metabolites. 12. PMID 36144188 DOI: 10.3390/metabo12090783  0.132
2021 Hong S, Giese AK, Schirmer MD, Bonkhoff AK, Bretzner M, Rist P, Dalca AV, Regenhardt RW, Etherton MR, Donahue KL, Nardin M, Mocking SJT, McIntosh EC, Attia J, Benavente OR, ... ... McDonough CW, et al. Excessive White Matter Hyperintensity Increases Susceptibility to Poor Functional Outcomes After Acute Ischemic Stroke. Frontiers in Neurology. 12: 700616. PMID 34566844 DOI: 10.3389/fneur.2021.700616  0.131
2022 Beitelshees AL, Thomas CD, Empey PE, Stouffer GA, Angiolillo DJ, Franchi F, Tuteja S, Limdi NA, Lee JC, Duarte JD, Kreutz RP, Skaar TC, Coons JC, Giri J, McDonough CW, et al. Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention in Diverse Clinical Settings. Journal of the American Heart Association. 11: e024159. PMID 35156424 DOI: 10.1161/JAHA.121.024159  0.13
2020 Orlando LA, Sperber NR, Voils C, Nichols M, Myers RA, Wu RR, Rakhra-Burris T, Levy KD, Levy M, Pollin TI, Guan Y, Horowitz CR, Ramos M, Kimmel SE, McDonough CW, et al. Correction: Developing a common framework for evaluating the implementation of genomic medicine interventions in clinical care: the IGNITE Network's Common Measures Working Group. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 32719392 DOI: 10.1038/s41436-020-0910-6  0.119
2013 McDonough C, Dunkley AJ, Aujla N, Morris D, Davies MJ, Khunti K. The association between body mass index and health-related quality of life: influence of ethnicity on this relationship. Diabetes, Obesity & Metabolism. 15: 342-8. PMID 23137289 DOI: 10.1111/dom.12033  0.116
2015 Shroads AL, Coats BS, McDonough CW, Langaee T, Stacpoole PW. Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children. Journal of Clinical Pharmacology. 55: 50-5. PMID 25079374 DOI: 10.1002/jcph.371  0.115
2015 McDonough CW, McClure LA, Mitchell BD, Gong Y, Horenstein RB, Lewis JP, Field TS, Talbert RL, Benavente OR, Johnson JA, Shuldiner AR. CYP2C19 metabolizer status and clopidogrel efficacy in the Secondary Prevention of Small Subcortical Strokes (SPS3) study. Journal of the American Heart Association. 4: e001652. PMID 26019129 DOI: 10.1161/Jaha.114.001652  0.115
2020 McDonough CW, Babcock K, Chucri K, Crawford DC, Bian J, Modave F, Cooper-DeHoff RM, Hogan WR. Optimizing identification of resistant hypertension: Computable phenotype development and validation. Pharmacoepidemiology and Drug Safety. PMID 32844549 DOI: 10.1002/Pds.5095  0.107
2014 Gong Y, McDonough CW, Padmanabhan S, Johnson JA. Hypertension Pharmacogenomics Handbook of Pharmacogenomics and Stratified Medicine. 747-778. DOI: 10.1016/B978-0-12-386882-4.00032-3  0.102
2023 Gawronski BE, Cicali EJ, McDonough CW, Cottler LB, Duarte JD. Exploring perceptions, knowledge, and attitudes regarding pharmacogenetic testing in the medically underserved. Frontiers in Genetics. 13: 1085994. PMID 36712853 DOI: 10.3389/fgene.2022.1085994  0.092
2018 Smith SM, McAuliffe K, Hall JM, McDonough CW, Gurka MJ, Robinson TO, Sacco RL, Pepine C, Shenkman E, Cooper-DeHoff RM. Hypertension in Florida: Data From the OneFlorida Clinical Data Research Network. Preventing Chronic Disease. 15: E27. PMID 29494332 DOI: 10.5888/Pcd15.170332  0.092
2022 Bonkhoff AK, Ullberg T, Bretzner M, Hong S, Schirmer MD, Regenhardt RW, Donahue KL, Nardin MJ, Dalca AV, Giese AK, Etherton MR, Hancock BL, Mocking SJT, McIntosh EC, Attia J, ... ... McDonough CW, et al. Deep profiling of multiple ischemic lesions in a large, multi-center cohort: Frequency, spatial distribution, and associations to clinical characteristics. Frontiers in Neuroscience. 16: 994458. PMID 36090258 DOI: 10.3389/fnins.2022.994458  0.083
2021 Vahabi N, McDonough CW, Desai AA, Cavallari LH, Duarte JD, Michailidis G. Cox-sMBPLS: An Algorithm for Disease Survival Prediction and Multi-Omics Module Discovery Incorporating -Regulatory Quantitative Effects. Frontiers in Genetics. 12: 701405. PMID 34408773 DOI: 10.3389/fgene.2021.701405  0.082
2019 Magvanjav O, Cooper-DeHoff RM, McDonough CW, Gong Y, Hogan WR, Johnson JA. Combination Antihypertensive Therapy Prescribing and Blood Pressure Control in a Real-World Setting. American Journal of Hypertension. PMID 31853537 DOI: 10.1093/ajh/hpz196  0.079
2020 McDonough CW, Smith SM, Cooper-DeHoff RM, Hogan WR. Optimizing Antihypertensive Medication Classification in Electronic Health Record-Based Data: Classification System Development and Methodological Comparison. Jmir Medical Informatics. 8: e14777. PMID 32130152 DOI: 10.2196/14777  0.078
2021 Bretzner M, Bonkhoff AK, Schirmer MD, Hong S, Dalca AV, Donahue KL, Giese AK, Etherton MR, Rist PM, Nardin M, Marinescu R, Wang C, Regenhardt RW, Leclerc X, Lopes R, ... ... McDonough CW, et al. MRI Radiomic Signature of White Matter Hyperintensities Is Associated With Clinical Phenotypes. Frontiers in Neuroscience. 15: 691244. PMID 34321995 DOI: 10.3389/fnins.2021.691244  0.073
2022 Bonkhoff AK, Hong S, Bretzner M, Schirmer MD, Regenhardt RW, Arsava EM, Donahue K, Nardin M, Dalca A, Giese AK, Etherton MR, Hancock BL, Mocking SJT, McIntosh E, Attia J, ... ... McDonough CW, et al. Association of Stroke Lesion Pattern and White Matter Hyperintensity Burden With Stroke Severity and Outcome. Neurology. PMID 35803717 DOI: 10.1212/WNL.0000000000200926  0.071
2017 Cavallari LH, Lee CR, Beitelshees AL, Cooper-DeHoff RM, Duarte JD, Voora D, Kimmel SE, McDonough CW, Gong Y, Dave CV, Pratt VM, Alestock TD, Anderson RD, Alsip J, Ardati AK, et al. Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention. Jacc. Cardiovascular Interventions. PMID 29102571 DOI: 10.1016/J.Jcin.2017.07.022  0.064
2019 Simpkins AN, McDonough CW, McClure LA, Mitchell BD, Shuldiner AR, Benavente OR, Johnson JA. Abstract 37: Secondary Stroke Prevention With Aspirin and Clopidogrel in CYP2C19 *17 Carriers Increases Risk of Major Non-CNS Bleeding Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.37  0.063
2016 Dotson VM, Hsu FC, Langaee TY, McDonough CW, King AC, Cohen RA, Newman AB, Kritchevsky SB, Myers V, Manini TM, Pahor M. Genetic Moderators of the Impact of Physical Activity on Depressive Symptoms. The Journal of Frailty & Aging. 5: 6-14. PMID 26980363 DOI: 10.14283/Jfa.2016.76  0.059
2022 Bonkhoff AK, Schirmer MD, Bretzner M, Hong S, Regenhardt RW, Donahue KL, Nardin MJ, Dalca AV, Giese AK, Etherton MR, Hancock BL, Mocking SJT, McIntosh EC, Attia J, Cole JW, ... ... McDonough CW, et al. The relevance of rich club regions for functional outcome post-stroke is enhanced in women. Human Brain Mapping. PMID 36440953 DOI: 10.1002/hbm.26159  0.058
2019 Mehanna M, Wang Z, Gong Y, McDonough CW, Beitelshees AL, Gums JG, Chapman AB, Schwartz GL, Bailey KR, Johnson JA, Turner ST, Cooper-Dehoff RM. Response to: Heterogeneous Treatment Response by Race Cannot Be Claimed in the Absence of Evidence. American Journal of Hypertension. PMID 31891170 DOI: 10.1093/Ajh/Hpz168  0.038
2022 Bretzner M, Bonkhoff AK, Schirmer MD, Hong S, Dalca A, Donahue K, Giese AK, Etherton MR, Rist PM, Nardin M, Regenhardt RW, Leclerc X, Lopes R, Gautherot M, Wang C, ... ... McDonough CW, et al. Radiomics-Derived Brain Age Predicts Functional Outcome After Acute Ischemic Stroke. Neurology. PMID 36443016 DOI: 10.1212/WNL.0000000000201596  0.037
2022 Bonkhoff AK, Bretzner M, Hong S, Schirmer MD, Cohen A, Regenhardt RW, Donahue KL, Nardin MJ, Dalca AV, Giese AK, Etherton MR, Hancock BL, Mocking SJT, McIntosh EC, Attia J, ... ... McDonough CW, et al. Sex-specific lesion pattern of functional outcomes after stroke. Brain Communications. 4: fcac020. PMID 35282166 DOI: 10.1093/braincomms/fcac020  0.037
2021 Bonkhoff AK, Schirmer MD, Bretzner M, Hong S, Regenhardt RW, Brudfors M, Donahue KL, Nardin MJ, Dalca AV, Giese AK, Etherton MR, Hancock BL, Mocking SJT, McIntosh EC, Attia J, ... ... McDonough CW, et al. Outcome after acute ischemic stroke is linked to sex-specific lesion patterns. Nature Communications. 12: 3289. PMID 34078897 DOI: 10.1038/s41467-021-23492-3  0.031
2019 McDonough CW, Breitenstein MK, Shahin M, Empey PE, Freimuth RR, Li L, Liebman M, Tuteja S. Translational Informatics Connects Real-World Information to Knowledge in an Increasingly Data-Driven World. Clinical Pharmacology and Therapeutics. PMID 31837229 DOI: 10.1002/Cpt.1719  0.014
2018 Ryan KA, Ay H, Worrall BB, McArdle PF, Cole JW, Meschia JF, Brown RD, Abedi V, Zand R, Wassertheil-Smoller S, Sudlow CL, Rundek T, Sacco RL, Rexrode K, Lindgren A, ... McDonough CW, et al. Abstract WMP51: Towards a Simplified Method for Ischemic Stroke Subtyping Suitable for Electronic Medical Record Systems Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Wmp51  0.01
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