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Donald W. Bowden - Publications

Affiliations: 
Biochemistry and Molecular Biology Wake Forest University, Winston-Salem, NC, United States 
Area:
Genetics, Biochemistry, Pathology
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417 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Melloni GEM, Kanoni S, Rayner NW, Bocher O, Arruda AL, Sonehara K, Namba S, ... ... Bowden DW, et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature. PMID 38374256 DOI: 10.1038/s41586-024-07019-6  0.35
2023 Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier K, Chittoor G, Josyula NS, Li X, Li Z, Allison MA, Becker DM, Bielak LF, ... ... Bowden DW, et al. WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE. Medrxiv : the Preprint Server For Health Sciences. PMID 37662265 DOI: 10.1101/2023.08.21.23293271  0.33
2023 Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Rayner NW, Bocher O, Ana Luiza de SVA, Sonehara K, Namba S, Lee SSK, Preuss MH, ... ... Bowden DW, et al. Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications. Medrxiv : the Preprint Server For Health Sciences. PMID 37034649 DOI: 10.1101/2023.03.31.23287839  0.367
2022 Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, ... ... Bowden DW, et al. A saturated map of common genetic variants associated with human height. Nature. PMID 36224396 DOI: 10.1038/s41586-022-05275-y  0.389
2022 Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, ... ... Bowden DW, et al. Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nature Genetics. PMID 35551307 DOI: 10.1038/s41588-022-01058-3  0.403
2022 Taub MA, Conomos MP, Keener R, Iyer KR, Weinstock JS, Yanek LR, Lane J, Miller-Fleming TW, Brody JA, Raffield LM, McHugh CP, Jain D, Gogarten SM, Laurie CA, Keramati A, ... ... Bowden DW, et al. Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed. Cell Genomics. 2. PMID 35530816 DOI: 10.1016/j.xgen.2021.100084  0.334
2022 Loh M, Zhang W, Ng HK, Schmid K, Lamri A, Tong L, Ahmad M, Lee JJ, Ng MCY, Petty LE, Spracklen CN, Takeuchi F, Islam MT, Jasmine F, Kasturiratne A, ... ... Bowden DW, et al. Identification of genetic effects underlying type 2 diabetes in South Asian and European populations. Communications Biology. 5: 329. PMID 35393509 DOI: 10.1038/s42003-022-03248-5  0.373
2021 Hindy G, Dornbos P, Chaffin MD, Liu DJ, Wang M, Selvaraj MS, Zhang D, Park J, Aguilar-Salinas CA, Antonacci-Fulton L, Ardissino D, Arnett DK, Aslibekyan S, Atzmon G, Ballantyne CM, ... ... Bowden DW, et al. Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes. American Journal of Human Genetics. PMID 34932938 DOI: 10.1016/j.ajhg.2021.11.021  0.304
2021 Lu Y, Dimitrov L, Chen SH, Bielak LF, Bis JC, Feitosa MF, Lu L, Kavousi M, Raffield LM, Smith AV, Wang L, Weiss S, Yao J, Zhu J, Gudmundsson EF, ... ... Bowden DW, et al. Multiethnic Genome-wide Association Study of Subclinical Atherosclerosis in Individuals with Type 2 Diabetes. Circulation. Genomic and Precision Medicine. PMID 34241534 DOI: 10.1161/CIRCGEN.120.003258  0.427
2021 Sobrin L, Susarla G, Stanwyck L, Rouhana JM, Li A, Pollack S, Igo RP, Jensen RA, Li X, Ng MCY, Smith AV, Kuo JZ, Taylor KD, Freedman BI, Bowden DW, et al. Gene Set Enrichment Analyses Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy. American Journal of Ophthalmology. PMID 34166655 DOI: 10.1016/j.ajo.2021.06.014  0.367
2021 Goodrich JK, Singer-Berk M, Son R, Sveden A, Wood J, England E, Cole JB, Weisburd B, Watts N, Caulkins L, Dornbos P, Koesterer R, Zappala Z, Zhang H, Maloney KA, ... ... Bowden DW, et al. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. Nature Communications. 12: 3505. PMID 34108472 DOI: 10.1038/s41467-021-23556-4  0.321
2021 Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, ... ... Bowden DW, et al. The trans-ancestral genomic architecture of glycemic traits. Nature Genetics. PMID 34059833 DOI: 10.1038/s41588-021-00852-9  0.366
2021 Palmer ND, Lu L, Register TC, Lenchik L, Carr JJ, Hicks PJ, Smith SC, Xu J, Dimitrov L, Keaton J, Guan M, Ng MCY, Chen YI, Hanley AJ, Engelman CD, ... ... Bowden DW, et al. Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. Plos One. 16: e0251423. PMID 34014961 DOI: 10.1371/journal.pone.0251423  0.326
2021 Graff M, Justice AE, Young KL, Marouli E, Zhang X, Fine RS, Lim E, Buchanan V, Rand K, Feitosa MF, Wojczynski MK, Yanek LR, Shao Y, Rohde R, Adeyemo AA, ... ... Bowden DW, et al. Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. American Journal of Human Genetics. PMID 33713608 DOI: 10.1016/j.ajhg.2021.02.011  0.351
2020 Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Aslibekyan S, Ballantyne CM, Bielak LF, Blangero J, Boerwinkle E, Bowden DW, et al. Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nature Genetics. PMID 32839606 DOI: 10.1038/S41588-020-0676-4  0.399
2020 Spracklen CN, Horikoshi M, Kim YJ, Lin K, Bragg F, Moon S, Suzuki K, Tam CHT, Tabara Y, Kwak SH, Takeuchi F, Long J, Lim VJY, Chai JF, Chen CH, ... ... Bowden DW, et al. Identification of type 2 diabetes loci in 433,540 East Asian individuals. Nature. PMID 32499647 DOI: 10.1038/S41586-020-2263-3  0.521
2020 de Las Fuentes L, Sung YJ, Noordam R, Winkler T, Feitosa MF, Schwander K, Bentley AR, Brown MR, Guo X, Manning A, Chasman DI, Aschard H, Bartz TM, Bielak LF, Campbell A, ... ... Bowden DW, et al. Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Molecular Psychiatry. PMID 32372009 DOI: 10.1038/S41380-020-0719-3  0.352
2020 Pollack S, Igo RP, Jensen RA, Christiansen M, Li X, Cheng CY, Ng MCY, Smith AV, Rossin EJ, Segrè AV, Davoudi S, Tan GS, Ida Chen YD, Kuo JZ, Dimitrov LM, ... ... Bowden DW, et al. Erratum. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes 2019;68:441-456. Diabetes. PMID 32341040 DOI: 10.2337/Db20-Er06A  0.434
2019 Singleton MJ, German C, Hari KJ, Saylor G, Herrington DM, Soliman EZ, Freedman BI, Bowden DW, Bhave PD, Yeboah J. QRS duration is associated with all-cause mortality in type 2 diabetes: The diabetes heart study. Journal of Electrocardiology. 58: 150-154. PMID 31895990 DOI: 10.1016/J.Jelectrocard.2019.11.053  0.386
2019 Kowalski MH, Qian H, Hou Z, Rosen JD, Tapia AL, Shan Y, Jain D, Argos M, Arnett DK, Avery C, Barnes KC, Becker LC, Bien SA, Bis JC, Blangero J, ... ... Bowden DW, et al. Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations. Plos Genetics. 15: e1008500. PMID 31869403 DOI: 10.1371/Journal.Pgen.1008500  0.463
2019 Brown LK, Xu J, Freedman BI, Hsu FC, Bowden DW, Koch KL. Symptoms Suggestive of Gastroparesis in a Community-Based Cohort of European Americans and African Americans with Type 2 Diabetes Mellitus. Digestive Diseases and Sciences. PMID 31820181 DOI: 10.1007/S10620-019-05974-Z  0.408
2019 Hauser MA, Allingham RR, Aung T, Van Der Heide CJ, Taylor KD, Rotter JI, Wang SJ, Bonnemaijer PWM, Williams SE, Abdullahi SM, Abu-Amero KK, Anderson MG, Akafo S, Alhassan MB, ... ... Bowden DW, et al. Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry. Jama. 322: 1682-1691. PMID 31688885 DOI: 10.1001/Jama.2019.16161  0.692
2019 Malhotra R, Mauer AC, Lino Cardenas CL, Guo X, Yao J, Zhang X, Wunderer F, Smith AV, Wong Q, Pechlivanis S, Hwang SJ, Wang J, Lu L, Nicholson CJ, Shelton G, ... ... Bowden DW, et al. HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype. Nature Genetics. PMID 31659325 DOI: 10.1038/S41588-019-0514-8  0.339
2019 Liu M, Frej C, Langefeld CD, Divers J, Bowden DW, Carr JJ, Gebre AK, Xu J, Larsson B, Dahlback B, Freedman BI, Parks JS. Plasma Apolipoprotein M and Sphingosine-1-Phosphate Levels are Inversely Associated with Mortality in African Americans with Type 2 Diabetes Mellitus. Journal of Lipid Research. PMID 31133557 DOI: 10.1194/Jlr.P089409  0.357
2019 Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR, Guo X, Schwander K, Manning AK, Brown MR, Aschard H, Feitosa MF, Franceschini N, ... ... Bowden DW, et al. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Human Molecular Genetics. PMID 31127295 DOI: 10.1093/Hmg/Ddz070  0.349
2019 Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, ... ... Bowden DW, et al. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. PMID 31118516 DOI: 10.1038/s41586-019-1231-2  0.388
2019 Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, ... ... Bowden DW, et al. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Human Genomics. 13: 21. PMID 31092297 DOI: 10.1186/S40246-019-0205-7  0.531
2019 Tucker BM, Hsu FC, Register TC, Xu J, Smith SC, Murea M, Bowden DW, Freedman BI, Lenchik L. Psoas and Paraspinous Muscle Measurements on Computed Tomography Predict Mortality in European Americans with Type 2 Diabetes Mellitus. The Journal of Frailty & Aging. 8: 72-78. PMID 30997919 DOI: 10.14283/Jfa.2019.5  0.311
2019 Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo X, Liu J, Lu Y, Cheng CY, Sim X, ... ... Bowden DW, et al. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nature Genetics. 51: 636-648. PMID 30926973 DOI: 10.1038/S41588-019-0378-Y  0.329
2019 Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL, Fine RS, Guo X, Schurmann C, Lempradl A, Marouli E, Mahajan A, Winkler TW, ... ... Bowden DW, et al. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics. PMID 30778226 DOI: 10.1038/S41588-018-0334-2  0.355
2019 de Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, Schwander K, Kraja AT, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, ... ... Bowden DW, et al. Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. American Journal of Epidemiology. PMID 30698716 DOI: 10.1093/Aje/Kwz005  0.362
2019 Kilpeläinen TO, Bentley AR, Noordam R, Sung YJ, Schwander K, Winkler TW, Jakupović H, Chasman DI, Manning A, Ntalla I, Aschard H, Brown MR, de Las Fuentes L, Franceschini N, Guo X, ... ... Bowden DW, et al. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nature Communications. 10: 376. PMID 30670697 DOI: 10.1038/S41467-018-08008-W  0.317
2019 Prasada S, Oswalt C, Yeboah P, Saylor G, Bowden D, Yeboah J. Heart rate is an independent predictor of all-cause mortality in individuals with type 2 diabetes: The diabetes heart study. World Journal of Diabetes. 9: 33-39. PMID 29359027 DOI: 10.4239/Wjd.V9.I1.33  0.365
2019 BOWDEN DW, XU J, FREEDMAN BI, PALMER N, HSU F. 1664-P: Does “Healthy Diabetes” Exist? Long-Term Survival in Diabetes Heart Study Participants Diabetes. 68: 1664-P. DOI: 10.2337/Db19-1664-P  0.344
2019 Cox AJ, Zhang P, Bowden DW, Devereaux B, Davoren PM, Cripps AW, West NP. Increased intestinal permeability as a risk factor for type 2 diabetes in obesity Obesity Research & Clinical Practice. 13: 40. DOI: 10.1016/J.Orcp.2016.10.053  0.349
2018 Kraja AT, Liu C, Fetterman JL, Graff M, Have CT, Gu C, Yanek LR, Feitosa MF, Arking DE, Chasman DI, Young K, Ligthart S, Hill WD, Weiss S, Luan J, ... ... Bowden DW, et al. Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. American Journal of Human Genetics. PMID 30595373 DOI: 10.1016/J.Ajhg.2018.12.001  0.45
2018 Franceschini N, Giambartolomei C, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, ... ... Bowden DW, et al. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nature Communications. 9: 5141. PMID 30510157 DOI: 10.1038/S41467-018-07340-5  0.354
2018 Pollack S, Igo RP, Jensen RA, Christiansen M, Li X, Cheng CY, Ng MCY, Smith AV, Rossin EJ, Segrè AV, Davoudi S, Tan GS, Ida Chen YD, Kuo JZ, Dimitrov LM, ... ... Bowden DW, et al. Multiethnic Genome-wide Association Study of Diabetic Retinopathy using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes. PMID 30487263 DOI: 10.2337/Db18-0567  0.542
2018 Taylor KD, Guo X, Zangwill LM, Liebmann JM, Girkin CA, Feldman RM, Dubiner H, Hai Y, Samuels BC, Panarelli JF, Mitchell JP, Al-Aswad LA, Park SC, Tello C, Cotliar J, ... ... Bowden DW, et al. Genetic Architecture of Primary Open Angle Glaucoma in Individuals of African Descent: The African Descent & Glaucoma Evaluation Study (ADAGES) III. Ophthalmology. PMID 30352225 DOI: 10.1016/J.Ophtha.2018.10.031  0.324
2018 Mahajan A, Taliun D, Thurner M, Robertson NR, Torres JM, Rayner NW, Payne AJ, Steinthorsdottir V, Scott RA, Grarup N, Cook JP, Schmidt EM, Wuttke M, Sarnowski C, Mägi R, ... ... Bowden DW, et al. Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nature Genetics. PMID 30297969 DOI: 10.1038/S41588-018-0241-6  0.47
2018 Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Wilson JG, Freedman BI, Bowden DW, Ng MCY. An Exome-wide Association Study for Type 2 Diabetes-Attributed End-Stage Kidney Disease in African Americans. Kidney International Reports. 3: 867-878. PMID 29989002 DOI: 10.1016/J.Ekir.2018.03.002  0.512
2018 Feitosa MF, Kraja AT, Chasman DI, Sung YJ, Winkler TW, Ntalla I, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Bentley AR, ... ... Bowden DW, et al. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Plos One. 13: e0198166. PMID 29912962 DOI: 10.1371/Journal.Pone.0198166  0.362
2018 Langefeld CD, Comeau ME, Ng MCY, Guan M, Dimitrov L, Mudgal P, Spainhour MH, Julian BA, Edberg JC, Croker JA, Divers J, Hicks PJ, Bowden DW, Chan GC, Ma L, et al. Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions. Kidney International. PMID 29885931 DOI: 10.1016/J.Kint.2018.03.017  0.506
2018 Lenchik L, Register TC, Russell GB, Xu J, Smith SC, Bowden DW, Divers J, Freedman BI. Volumetric bone mineral density of the spine predicts mortality in African-American men with type 2 diabetes. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 29855664 DOI: 10.1007/S00198-018-4578-6  0.361
2018 Raffield LM, Cox AJ, Criqui MH, Hsu FC, Terry JG, Xu J, Freedman BI, Carr JJ, Bowden DW. Associations of coronary artery calcified plaque density with mortality in type 2 diabetes: the Diabetes Heart Study. Cardiovascular Diabetology. 17: 67. PMID 29751802 DOI: 10.1186/S12933-018-0714-Z  0.361
2018 Hayek SS, Divers J, Raad M, Xu J, Bowden DW, Tracy M, Reiser J, Freedman BI. Predicting Mortality in African Americans With Type 2 Diabetes Mellitus: Soluble Urokinase Plasminogen Activator Receptor, Coronary Artery Calcium, and High-Sensitivity C-Reactive Protein. Journal of the American Heart Association. 7. PMID 29716888 DOI: 10.1161/Jaha.117.008194  0.39
2018 Keaton JM, Gao C, Guan M, Hellwege JN, Palmer ND, Pankow JS, Fornage M, Wilson JG, Correa A, Rasmussen-Torvik LJ, Rotter JI, Chen YI, Taylor KD, Rich SS, Wagenknecht LE, ... ... Bowden DW, et al. Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans. Genetic Epidemiology. PMID 29691896 DOI: 10.1002/Gepi.22126  0.725
2018 Murea M, Lenchik L, Register TC, Russell GB, Xu J, Smith SC, Bowden DW, Divers J, Freedman BI. Psoas and paraspinous muscle index as a predictor of mortality in African American men with type 2 diabetes mellitus. Journal of Diabetes and Its Complications. PMID 29627372 DOI: 10.1016/J.Jdiacomp.2018.03.004  0.349
2018 Gao C, Tabb KL, Dimitrov LM, Taylor KD, Wang N, Guo X, Long J, Rotter JI, Watanabe RM, Curran JE, Blangero J, Langefeld CD, Bowden DW, Palmer ND. Exome Sequencing Identifies Genetic Variants Associated with Circulating Lipid Levels in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study (IRASFS). Scientific Reports. 8: 5603. PMID 29618726 DOI: 10.1038/S41598-018-23727-2  0.464
2018 Sung YJ, Winkler TW, de Las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I, Guo X, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, ... ... Bowden DW, et al. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. American Journal of Human Genetics. PMID 29455858 DOI: 10.1016/J.Ajhg.2018.01.015  0.419
2018 Langefeld CD, Comeau ME, Sharma NK, Bowden DW, Freedman BI, Das SK. Transcriptional Regulatory Mechanisms in Adipose and Muscle Tissue Associated with Composite Glucometabolic Phenotypes. Obesity (Silver Spring, Md.). PMID 29377571 DOI: 10.1002/Oby.22113  0.332
2018 Chan GC, Divers J, Russell GB, Langefeld CD, Wagenknecht LE, Xu J, Smith SC, Bowden DW, Register TC, Carr JJ, Lenchik L, Freedman BI. Adipose tissue depot volume relationships with spinal trabecular bone mineral density in African Americans with diabetes. Plos One. 13: e0191674. PMID 29364924 DOI: 10.1371/Journal.Pone.0191674  0.375
2018 Zangwill LM, Ayyagari R, Liebmann JM, Girkin CA, Feldman R, Dubiner H, Dirkes KA, Holmann M, Williams-Steppe E, Hammel N, Saunders LJ, Vega S, Sandow K, Roll K, Slight R, ... ... Bowden DW, et al. The African Descent and Glaucoma Evaluation Study (ADAGES) III: Contribution of Genotype to Glaucoma Phenotype in African Americans: Study Design and Baseline Data. Ophthalmology. PMID 29361356 DOI: 10.1016/J.Ophtha.2017.11.031  0.33
2018 Hsu FC, Sink KM, Hugenschmidt CE, Williamson JD, Hughes TM, Palmer ND, Xu J, Smith SC, Wagner BC, Whitlow CT, Bowden DW, Maldjian JA, Divers J, Freedman BI. Cerebral structure and cognitive performance in African Americans and European Americans with type 2 diabetes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29309525 DOI: 10.1093/Gerona/Glx255  0.381
2018 Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, ... ... Bowden DW, et al. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics. 50: 26-41. PMID 29273807 DOI: 10.1038/S41588-017-0011-X  0.397
2018 Raad M, Hayek S, Xu J, Bowden D, Reiser J, Freedman B. SOLUBLE UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR COMPARED TO CORONARY ARTERY CALCIUM SCORE AND HIGH SENSITIVITY C REACTIVE PROTEIN IN PREDICTING DEATH IN AFRICAN AMERICANS WITH DIABETES Journal of the American College of Cardiology. 71: A1831. DOI: 10.1016/S0735-1097(18)32372-6  0.369
2017 Lenchik L, Register TC, Hsu FC, Xu J, Smith SC, Carr JJ, Freedman BI, Bowden DW. Bone Mineral Density of the Radius Predicts All-Cause Mortality in Patients With Type 2 Diabetes: Diabetes Heart Study. Journal of Clinical Densitometry : the Official Journal of the International Society For Clinical Densitometry. PMID 29284565 DOI: 10.1016/J.Jocd.2017.11.003  0.354
2017 Jason F, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Bowden DW, et al. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 4: 170179. PMID 29257133 DOI: 10.1038/Sdata.2017.179  0.443
2017 Divers J, Palmer ND, Langefeld CD, Brown WM, Lu L, Hicks PJ, Smith SC, Xu J, Terry JG, Register TC, Wagenknecht LE, Parks JS, Ma L, Chan GC, Buxbaum SG, ... ... Bowden DW, et al. Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes. Bmc Genetics. 18: 105. PMID 29221444 DOI: 10.1186/S12863-017-0572-9  0.505
2017 Cox AJ, Zhang P, Bowden DW, Devereaux B, Davoren PM, Cripps AW, West NP. Enteroendocrine and adipokine associations with type 2 diabetes: phenotypic risk scoring approaches. Journal of Gastroenterology and Hepatology. PMID 29193302 DOI: 10.1111/Jgh.14057  0.399
2017 Gao C, Langefeld CD, Ziegler JT, Taylor KD, Norris JM, Chen YI, Hellwege JN, Guo X, Allison MA, Speliotes EK, Rotter JI, Bowden DW, Wagenknecht LE, Palmer ND. Genome-Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sex-Specific Adiposity Loci in Mexican Americans. Obesity (Silver Spring, Md.). PMID 29178545 DOI: 10.1002/Oby.22074  0.672
2017 Barrett EJ, Liu Z, Khamaisi M, King GL, Klein R, Klein BEK, Hughes TM, Craft S, Freedman BI, Bowden DW, Vinik AI, Casellini CM. Diabetic Microvascular Disease: An Endocrine Society Scientific Statement. The Journal of Clinical Endocrinology and Metabolism. PMID 29126250 DOI: 10.1210/Jc.2017-01922  0.375
2017 Chan GC, Divers J, Russell GB, Langefeld CD, Wagenknecht LE, Hsu FC, Xu J, Smith SC, Palmer ND, Hicks PJ, Bowden DW, Register TC, Ma L, Carr JJ, Freedman BI. FGF23 Concentration and APOL1 Genotype Are Novel Predictors of Mortality in African Americans With Type 2 Diabetes. Diabetes Care. PMID 29113983 DOI: 10.2337/Dc17-0820  0.424
2017 Sajuthi SP, Sharma NK, Comeau ME, Chou JW, Bowden DW, Freedman BI, Langefeld CD, Parks JS, Das SK. Genetic regulation of adipose tissue transcript expression is involved in modulating serum triglyceride and HDL-cholesterol. Gene. PMID 28844666 DOI: 10.1016/J.Gene.2017.08.019  0.405
2017 Gomadam P, Shah A, Qureshi W, Yeboah PN, Freedman BI, Bowden D, Soliman EZ, Yeboah J. Blood pressure indices and cardiovascular disease mortality in persons with or without diabetes mellitus. Journal of Hypertension. PMID 28800042 DOI: 10.1097/Hjh.0000000000001509  0.335
2017 Freedman BI, Sink KM, Hugenschmidt CE, Hughes TM, Williamson JD, Whitlow CT, Palmer ND, Miller ME, Lovato LC, Xu J, Smith SC, Launer LJ, Barzilay JI, Cohen RM, Sullivan MD, ... ... Bowden DW, et al. Associations of Early Kidney Disease With Brain Magnetic Resonance Imaging and Cognitive Function in African Americans With Type 2 Diabetes Mellitus. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 28648301 DOI: 10.1053/J.Ajkd.2017.05.006  0.416
2017 Tabb KL, Gao C, Hicks PJ, Hawkins GA, Rotter JI, Chen YI, Guo X, Norris JM, Lorenzo C, Freedman BI, Bowden DW, Palmer ND. Adiponectin isoform patterns in ethnic-specific ADIPOQ mutation carriers: The IRAS family study. Obesity (Silver Spring, Md.). PMID 28643464 DOI: 10.1002/Oby.21892  0.321
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2017 Gao C, Hsu FC, Dimitrov LM, Okut H, Chen YI, Taylor KD, Rotter JI, Langefeld CD, Bowden DW, Palmer ND. A genome-wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study. Genetic Epidemiology. PMID 28378447 DOI: 10.1002/Gepi.22042  0.537
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2016 Hsu FC, Yuan M, Bowden DW, Xu J, Smith SC, Wagenknecht LE, Langefeld CD, Divers J, Register TC, Carr JJ, Williamson JD, Sink KM, Maldjian JA, Freedman BI. Adiposity is inversely associated with hippocampal volume in African Americans and European Americans with diabetes. Journal of Diabetes and Its Complications. PMID 27615667 DOI: 10.1016/J.Jdiacomp.2016.08.012  0.404
2016 Wagenknecht LE, Divers J, Register TC, Russell GB, Bowden DW, Xu J, Langefeld CD, Lenchik L, Hruska KA, Carr JJ, Freedman BI. Bone mineral density and progression of subclinical atherosclerosis in African Americans with type 2 diabetes. The Journal of Clinical Endocrinology and Metabolism. jc20161934. PMID 27552541 DOI: 10.1210/Jc.2016-1934  0.388
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2016 Nielson CM, Liu CT, Smith AV, Ackert-Bicknell CL, Reppe S, Johanna J, Wassel C, Register TC, Oei L, Alonso Lopez N, Oei EH, Parimi N, Samelson EJ, Nalls MA, Zmuda J, ... ... Bowden D, et al. Novel Genetic Variants are Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SCL1A3 and EPHB2. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27476799 DOI: 10.1002/Jbmr.2913  0.41
2016 Guan M, Ma J, Keaton JM, Dimitrov L, Mudgal P, Stromberg M, Bonomo JA, Hicks PJ, Freedman BI, Bowden DW, Ng MC. Association of kidney structure-related gene variants with type 2 diabetes-attributed end-stage kidney disease in African Americans. Human Genetics. PMID 27461219 DOI: 10.1007/S00439-016-1714-2  0.848
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2016 Freedman BI, Gadegbeku CA, Bryan RN, Palmer ND, Hicks PJ, Ma L, Rocco MV, Smith SC, Xu J, Whitlow CT, Wagner BC, Langefeld CD, Hawfield AT, Bates JT, Lerner AJ, ... ... Bowden DW, et al. APOL1 renal-risk variants associate with reduced cerebral white matter lesion volume and increased gray matter volume. Kidney International. PMID 27342958 DOI: 10.1016/J.Kint.2016.04.027  0.376
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2016 Palmer ND, Wagenknecht LE, Langefeld CD, Wang N, Buchanan TA, Xiang AH, Allayee H, Bergman RN, Raffel LJ, Ida Chen YD, Haritunians T, Fingerlin T, Goodarzi MO, Taylor KD, Rotter JI, ... ... Bowden DW, et al. Improved Performance of Dynamic Measures of Insulin Response over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium. Diabetes. PMID 27207554 DOI: 10.2337/Db15-1543  0.378
2016 Ma J, Guan M, Bowden DW, Ng MC, Hicks PJ, Lea JP, Ma L, Gao C, Palmer ND, Freedman BI. Association Analysis of the Cubilin (CUBN) and Megalin (LRP2) Genes with ESRD in African Americans. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 27197912 DOI: 10.2215/Cjn.12971215  0.424
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2016 Ma L, Langefeld CD, Comeau ME, Bonomo JA, Rocco MV, Burkart JM, Divers J, Palmer ND, Hicks PJ, Bowden DW, Lea JP, Krisher JO, Clay MJ, Freedman BI. APOL1 renal-risk genotypes associate with longer hemodialysis survival in prevalent nondiabetic African American patients with end-stage renal disease. Kidney International. PMID 27157696 DOI: 10.1016/J.Kint.2016.02.032  0.802
2016 Williams RC, Elston RC, Kumar P, Knowler WC, Abboud HE, Adler S, Bowden DW, Divers J, Freedman BI, Igo RP, Ipp E, Iyengar SK, Kimmel PL, Klag MJ, Kohn O, et al. Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND). Bmc Genomics. 17: 325. PMID 27142425 DOI: 10.1186/S12864-016-2654-X  0.518
2016 Martelle SE, Raffield LM, Palmer ND, Cox AJ, Freedman BI, Hugenschmidt CE, Williamson JD, Bowden DW. Dopamine pathway gene variants may modulate cognitive performance in the DHS - Mind Study. Brain and Behavior. e00446. PMID 27066308 DOI: 10.1002/Brb3.446  0.389
2016 Palmer ND, Divers J, Lu L, Register TC, Carr JJ, Hicks PJ, Smith SC, Xu J, Judd SE, Irvin MR, Gutierrez OM, Bowden DW, Wagenknecht LE, Langefeld CD, Freedman BI. Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American-Diabetes Heart study. Bone. PMID 27032714 DOI: 10.1016/J.Bone.2016.01.028  0.467
2016 Adams JN, Raffield LM, Martelle SE, Freedman BI, Langefeld CD, Carr JJ, Cox AJ, Bowden DW. Genetic analysis of advanced glycation end products in the DHS MIND study. Gene. PMID 26915486 DOI: 10.1016/J.Gene.2016.02.029  0.551
2016 Sharma NK, Sajuthi SP, Chou JW, Calles-Escandon J, Demons J, Rogers S, Ma L, Palmer ND, R McWilliams D, Beal J, Comeau M, Cherry K, Hawkins GA, Menon L, Kouba E, ... ... Bowden DW, et al. Tissue-specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans. The Journal of Clinical Endocrinology and Metabolism. jc20153336. PMID 26789776 DOI: 10.1210/Jc.2015-3336  0.351
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2015 Adams JN, Martelle SE, Raffield LM, Freedman BI, Langefeld CD, Hsu FC, Maldjian JA, Williamson JD, Hugenschmidt CE, Carr JJ, Cox AJ, Bowden DW. Analysis of Advanced Glycation End Products in the DHS Mind Study. Journal of Diabetes and Its Complications. PMID 26739237 DOI: 10.1016/J.Jdiacomp.2015.11.025  0.41
2015 Freedman BI, Divers J, Russell GB, Palmer ND, Bowden DW, Carr JJ, Wagenknecht LE, Hightower RC, Xu J, Smith SC, Langefeld CD, Hruska KA, Register TC. Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus. American Journal of Nephrology. 42: 391-401. PMID 26693712 DOI: 10.1159/000443241  0.319
2015 Sink KM, Craft S, Smith SC, Maldjian JA, Bowden DW, Xu J, Freedman BI, Divers J. Montreal Cognitive Assessment and Modified Mini Mental State Examination in African Americans. Journal of Aging Research. 2015: 872018. PMID 26618003 DOI: 10.1155/2015/872018  0.312
2015 Gao C, Wang N, Guo X, Ziegler JT, Taylor KD, Xiang AH, Hai Y, Kridel SJ, Nadler JL, Kandeel F, Raffel LJ, Chen YI, Norris JM, Rotter JI, Watanabe RM, ... ... Bowden DW, et al. A Comprehensive Analysis of Common and Rare Variants to Identify Adiposity Loci in Hispanic Americans: The IRAS Family Study (IRASFS). Plos One. 10: e0134649. PMID 26599207 DOI: 10.1371/Journal.Pone.0134649  0.509
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2015 Raffield LM, Cox AJ, Freedman BI, Hugenschmidt CE, Hsu FC, Wagner BC, Xu J, Maldjian JA, Bowden DW. Analysis of the relationships between type 2 diabetes status, glycemic control, and neuroimaging measures in the Diabetes Heart Study Mind. Acta Diabetologica. PMID 26525870 DOI: 10.1007/S00592-015-0815-Z  0.403
2015 Bonomo JA, Palmer ND, He JC, Fan Y, Hicks PJ, Lea JP, Okusa MD, Bowden DW, Freedman BI. Association Analysis of the Reticulon 1 Gene in End-Stage Kidney Disease. American Journal of Nephrology. 42: 259-264. PMID 26496126 DOI: 10.1159/000441199  0.772
2015 Raffield LM, Brenes GA, Cox AJ, Freedman BI, Hugenschmidt CE, Hsu FC, Xu J, Wagner BC, Williamson JD, Maldjian JA, Bowden DW. Associations between anxiety and depression symptoms and cognitive testing and neuroimaging in type 2 diabetes. Journal of Diabetes and Its Complications. PMID 26476474 DOI: 10.1016/J.Jdiacomp.2015.09.010  0.327
2015 Freedman BI, Divers J, Whitlow CT, Bowden DW, Palmer ND, Smith SC, Xu J, Register TC, Carr JJ, Wagner BC, Williamson JD, Sink KM, Maldjian JA. Subclinical Atherosclerosis Is Inversely Associated With Gray Matter Volume in African Americans With Type 2 Diabetes. Diabetes Care. PMID 26370382 DOI: 10.2337/Dc15-1035  0.438
2015 Hawkins GA, Friedman DJ, Lu L, McWilliams DR, Chou JW, Sajuthi S, Divers J, Parekh RS, Li M, Genovese G, Pollack MR, Hicks PJ, Bowden DW, Ma L, Freedman BI, et al. Re-Sequencing of the APOL1-APOL4 and MYH9 Gene Regions in African Americans Does Not Identify Additional Risks for CKD Progression. American Journal of Nephrology. 42: 99-106. PMID 26343748 DOI: 10.1159/000439448  0.457
2015 Iyengar SK, Sedor JR, Freedman BI, Kao WH, Kretzler M, Keller BJ, Abboud HE, Adler SG, Best LG, Bowden DW, Burlock A, Chen YD, Cole SA, Comeau ME, Curtis JM, et al. Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND). Plos Genetics. 11: e1005352. PMID 26305897 DOI: 10.1371/Journal.Pgen.1005352  0.596
2015 VanderJagt TA, Neugebauer MH, Morgan M, Bowden DW, Shah VO. Epigenetic profiles of pre-diabetes transitioning to type 2 diabetes and nephropathy. World Journal of Diabetes. 6: 1113-21. PMID 26265998 DOI: 10.4239/Wjd.V6.I9.1113  0.436
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2015 Whitlow CT, Sink KM, Divers J, Smith SC, Xu J, Palmer ND, Hugenschmidt CE, Williamson JD, Bowden DW, Freedman BI, Maldjian JA. Effects of Type 2 Diabetes on Brain Structure and Cognitive Function: African American-Diabetes Heart Study MIND. Ajnr. American Journal of Neuroradiology. PMID 26206811 DOI: 10.3174/Ajnr.A4321  0.413
2015 Freedman BI, Divers J, Russell GB, Palmer ND, Wagenknecht LE, Smith SC, Xu J, Carr JJ, Bowden DW, Register TC. Vitamin D associations with renal, bone, and cardiovascular phenotypes: African American-Diabetes Heart Study. The Journal of Clinical Endocrinology and Metabolism. jc20152167. PMID 26196951 DOI: 10.1210/Jc.2015-2167  0.316
2015 Hsu FC, Raffield LM, Hugenschmidt CE, Cox A, Xu J, Carr JJ, Freedman BI, Maldjian JA, Williamson JD, Bowden DW. Relationships between Cognitive Performance, Neuroimaging and Vascular Disease: The DHS-MIND Study. Neuroepidemiology. 45: 1-11. PMID 26185004 DOI: 10.1159/000435775  0.33
2015 Raffield LM, Hsu FC, Cox AJ, Carr JJ, Freedman BI, Bowden DW. Predictors of all-cause and cardiovascular disease mortality in type 2 diabetes: Diabetes Heart Study. Diabetology & Metabolic Syndrome. 7: 58. PMID 26146522 DOI: 10.1186/S13098-015-0055-Y  0.384
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2015 Dauriz M, Porneala BC, Guo X, Bielak LF, Peyser PA, Durant NH, Carnethon MR, Bonadonna RC, Bonora E, Bowden DW, Florez JC, Fornage M, Hivert MF, Jacobs DR, Kabagambe EK, et al. Association of a 62 Variants Type 2 Diabetes Genetic Risk Score With Markers of Subclinical Atherosclerosis: A Transethnic, Multicenter Study. Circulation. Cardiovascular Genetics. 8: 507-15. PMID 25805414 DOI: 10.1161/Circgenetics.114.000740  0.446
2015 Belalcazar LM, Papandonatos GD, McCaffery JM, Peter I, Pajewski NM, Erar B, Allred ND, Balasubramanyam A, Bowden DW, Brautbar A, Pi-Sunyer FX, Ballantyne CM, Huggins GS. A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes. Physiological Genomics. 47: 215-24. PMID 25759378 DOI: 10.1152/Physiolgenomics.00109.2014  0.473
2015 Murea M, Hsu FC, Cox AJ, Hugenschmidt CE, Xu J, Adams JN, Raffield LM, Whitlow CT, Maldjian JA, Bowden DW, Freedman BI. Structural and functional assessment of the brain in European Americans with mild-to-moderate kidney disease: Diabetes Heart Study-MIND. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 25722384 DOI: 10.1093/Ndt/Gfv030  0.349
2015 Raffield LM, Cox AJ, Carr JJ, Freedman BI, Hicks PJ, Langefeld CD, Hsu FC, Bowden DW. Analysis of a cardiovascular disease genetic risk score in the Diabetes Heart Study. Acta Diabetologica. 52: 743-51. PMID 25700702 DOI: 10.1007/S00592-015-0720-5  0.533
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2015 Palmer ND, Goodarzi MO, Langefeld CD, Wang N, Guo X, Taylor KD, Fingerlin TE, Norris JM, Buchanan TA, Xiang AH, Haritunians T, Ziegler JT, Williams AH, Stefanovski D, Cui J, ... ... Bowden DW, et al. Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. Diabetes. 64: 1853-66. PMID 25524916 DOI: 10.2337/Db14-0732  0.464
2015 Raffield LM, Cox AJ, Hugenschmidt CE, Freedman BI, Langefeld CD, Williamson JD, Hsu FC, Maldjian JA, Bowden DW. Heritability and genetic association analysis of neuroimaging measures in the Diabetes Heart Study. Neurobiology of Aging. 36: 1602.e7-15. PMID 25523635 DOI: 10.1016/J.Neurobiolaging.2014.11.008  0.544
2015 Hellwege JN, Palmer ND, Mark Brown W, Brown MW, Ziegler JT, Sandy An S, An SS, Guo X, Ida Chen YD, Chen IY, Taylor K, Hawkins GA, Ng MC, Speliotes EK, Lorenzo C, ... ... Bowden DW, et al. Empirical characteristics of family-based linkage to a complex trait: the ADIPOQ region and adiponectin levels. Human Genetics. 134: 203-13. PMID 25447270 DOI: 10.1007/S00439-014-1511-8  0.804
2015 Palmer ND, Stevens RD, Antinozzi PA, Anderson A, Bergman RN, Wagenknecht LE, Newgard CB, Bowden DW. Metabolomic profile associated with insulin resistance and conversion to diabetes in the Insulin Resistance Atherosclerosis Study. The Journal of Clinical Endocrinology and Metabolism. 100: E463-8. PMID 25423564 DOI: 10.1210/Jc.2014-2357  0.361
2015 Yeo NC, O'Meara CC, Bonomo JA, Veth KN, Tomar R, Flister MJ, Drummond IA, Bowden DW, Freedman BI, Lazar J, Link BA, Jacob HJ. Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity. Genome Research. 25: 57-65. PMID 25273069 DOI: 10.1101/Gr.182881.114  0.791
2015 Palmer ND, Ng MC, Langefeld CD, Divers J, Lea JP, Okusa MD, Kimberly RP, Bowden DW, Freedman BI. Lack of Association of the APOL1 G3 Haplotype in African Americans with ESRD. Journal of the American Society of Nephrology : Jasn. 26: 1021-5. PMID 25249559 DOI: 10.1681/Asn.2014050444  0.457
2015 Sink KM, Divers J, Whitlow CT, Palmer ND, Smith SC, Xu J, Hugenschmidt CE, Wagner BC, Williamson JD, Bowden DW, Maldjian JA, Freedman BI. Cerebral structural changes in diabetic kidney disease: African American-Diabetes Heart Study MIND. Diabetes Care. 38: 206-12. PMID 25205141 DOI: 10.2337/Dc14-1231  0.43
2015 Freedman BI, Langefeld CD, Lu L, Palmer ND, Smith SC, Bagwell BM, Hicks PJ, Xu J, Wagenknecht LE, Raffield LM, Register TC, Carr JJ, Bowden DW, Divers J. APOL1 associations with nephropathy, atherosclerosis, and all-cause mortality in African Americans with type 2 diabetes. Kidney International. 87: 176-81. PMID 25054777 DOI: 10.1038/Ki.2014.255  0.423
2014 Cox AJ, Hsu FC, Agarwal S, Freedman BI, Herrington DM, Carr JJ, Bowden DW. Prediction of mortality using a multi-bed vascular calcification score in the Diabetes Heart Study. Cardiovascular Diabetology. 13: 160. PMID 25496604 DOI: 10.1186/S12933-014-0160-5  0.326
2014 Sellers MB, Divers J, Lu L, Xu J, Smith SC, Bowden DW, Herrington D, Freedman BI, Soliman EZ. Prevalence and determinants of electrocardiographic abnormalities in African Americans with type 2 diabetes. Journal of Epidemiology and Global Health. 4: 289-96. PMID 25455646 DOI: 10.1016/J.Jegh.2014.04.003  0.42
2014 Palmer ND, Sink KM, Smith SC, Xu J, Bowden DW, Hugenschmidt CE, Whitlow CT, Williamson JD, Maldjian JA, Divers J, Freedman BI. Kidney disease and cognitive function: African American-diabetes heart study MIND. American Journal of Nephrology. 40: 200-7. PMID 25323981 DOI: 10.1159/000367669  0.38
2014 Keaton JM, Cooke Bailey JN, Palmer ND, Freedman BI, Langefeld CD, Ng MC, Bowden DW. A comparison of type 2 diabetes risk allele load between African Americans and European Americans. Human Genetics. 133: 1487-95. PMID 25273842 DOI: 10.1007/S00439-014-1486-5  0.751
2014 Ng MC, Shriner D, Chen BH, Li J, Chen WM, Guo X, Liu J, Bielinski SJ, Yanek LR, Nalls MA, Comeau ME, Rasmussen-Torvik LJ, Jensen RA, Evans DS, Sun YV, ... ... Bowden DW, et al. Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. Plos Genetics. 10: e1004517. PMID 25102180 DOI: 10.1371/Journal.Pgen.1004517  0.791
2014 Raffield LM, Agarwal S, Cox AJ, Hsu FC, Carr JJ, Freedman BI, Xu J, Bowden DW, Vitolins MZ. Cross-sectional analysis of calcium intake for associations with vascular calcification and mortality in individuals with type 2 diabetes from the Diabetes Heart Study. The American Journal of Clinical Nutrition. 100: 1029-35. PMID 25099552 DOI: 10.3945/Ajcn.114.090365  0.351
2014 Bonomo JA, Guan M, Ng MC, Palmer ND, Hicks PJ, Keaton JM, Lea JP, Langefeld CD, Freedman BI, Bowden DW. The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease. Human Molecular Genetics. 23: 6441-7. PMID 25027322 DOI: 10.1093/Hmg/Ddu362  0.856
2014 Cox AJ, Hsu FC, Freedman BI, Herrington DM, Criqui MH, Carr JJ, Bowden DW. Contributors to mortality in high-risk diabetic patients in the Diabetes Heart Study. Diabetes Care. 37: 2798-803. PMID 24989706 DOI: 10.2337/Dc14-0081  0.386
2014 Bonomo JA, Ng MC, Palmer ND, Keaton JM, Larsen CP, Hicks PJ, Langefeld CD, Freedman BI, Bowden DW. Coding variants in nephrin (NPHS1) and susceptibility to nephropathy in African Americans. Clinical Journal of the American Society of Nephrology : Cjasn. 9: 1434-40. PMID 24948143 DOI: 10.2215/Cjn.00290114  0.816
2014 Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Diabetes Care. 37: 1751-8. PMID 24812433 DOI: 10.2337/Dc14-0396  0.328
2014 Adams JN, Raffield LM, Freedman BI, Langefeld CD, Ng MC, Carr JJ, Cox AJ, Bowden DW. Analysis of common and coding variants with cardiovascular disease in the Diabetes Heart Study. Cardiovascular Diabetology. 13: 77. PMID 24725463 DOI: 10.1186/1475-2840-13-77  0.554
2014 Hellwege JN, Palmer ND, Raffield LM, Ng MC, Hawkins GA, Long J, Lorenzo C, Norris JM, Ida Chen YD, Speliotes EK, Rotter JI, Langefeld CD, Wagenknecht LE, Bowden DW. Genome-wide family-based linkage analysis of exome chip variants and cardiometabolic risk. Genetic Epidemiology. 38: 345-52. PMID 24719370 DOI: 10.1002/Gepi.21801  0.754
2014 Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. The Journal of Clinical Endocrinology and Metabolism. 99: 1983-92. PMID 24712577 DOI: 10.1210/Jc.2014-1425  0.358
2014 Cox AJ, Hugenschmidt CE, Raffield LM, Langefeld CD, Freedman BI, Williamson JD, Hsu FC, Bowden DW. Heritability and genetic association analysis of cognition in the Diabetes Heart Study. Neurobiology of Aging. 35: 1958.e3-1958.e12. PMID 24684796 DOI: 10.1016/J.Neurobiolaging.2014.03.005  0.479
2014 Bonomo JA, Palmer ND, Hicks PJ, Lea JP, Okusa MD, Langefeld CD, Bowden DW, Freedman BI. Complement factor H gene associations with end-stage kidney disease in African Americans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 29: 1409-14. PMID 24586071 DOI: 10.1093/Ndt/Gfu036  0.857
2014 Flannick J, Thorleifsson G, Beer NL, Jacobs SB, Grarup N, Burtt NP, Mahajan A, Fuchsberger C, Atzmon G, Benediktsson R, Blangero J, Bowden DW, Brandslund I, Brosnan J, Burslem F, et al. Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nature Genetics. 46: 357-63. PMID 24584071 DOI: 10.1038/Ng.2915  0.438
2014 Cox AJ, Hsu FC, Ng MC, Langefeld CD, Freedman BI, Carr JJ, Bowden DW. Genetic risk score associations with cardiovascular disease and mortality in the Diabetes Heart Study. Diabetes Care. 37: 1157-64. PMID 24574349 DOI: 10.2337/Dc13-1514  0.498
2014 Cox AJ, Azeem A, Yeboah J, Soliman EZ, Aggarwal SR, Bertoni AG, Carr JJ, Freedman BI, Herrington DM, Bowden DW. Heart rate-corrected QT interval is an independent predictor of all-cause and cardiovascular mortality in individuals with type 2 diabetes: the Diabetes Heart Study. Diabetes Care. 37: 1454-61. PMID 24574343 DOI: 10.2337/Dc13-1257  0.383
2014 Palmer ND, Ng MC, Hicks PJ, Mudgal P, Langefeld CD, Freedman BI, Bowden DW. Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease. Plos One. 9: e88273. PMID 24551085 DOI: 10.1371/Journal.Pone.0088273  0.612
2014 Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, ... ... Bowden DW, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/Ng.2897  0.546
2014 Cooke Bailey JN, Palmer ND, Ng MC, Bonomo JA, Hicks PJ, Hester JM, Langefeld CD, Freedman BI, Bowden DW. Analysis of coding variants identified from exome sequencing resources for association with diabetic and non-diabetic nephropathy in African Americans. Human Genetics. 133: 769-79. PMID 24385048 DOI: 10.1007/S00439-013-1415-Z  0.851
2014 Register TC, Hruska KA, Divers J, Bowden DW, Palmer ND, Carr JJ, Wagenknecht LE, Hightower RC, Xu J, Smith SC, Dietzen DJ, Langefeld CD, Freedman BI. Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-Diabetes Heart Study. The Journal of Clinical Endocrinology and Metabolism. 99: 315-21. PMID 24178795 DOI: 10.1210/Jc.2013-3168  0.356
2014 Hellwege JN, Palmer ND, Ziegler JT, Langefeld CD, Lorenzo C, Norris JM, Takamura T, Bowden DW. Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics. Gene. 534: 33-9. PMID 24161883 DOI: 10.1016/J.Gene.2013.10.035  0.721
2014 Divers J, Palmer ND, Lu L, Langefeld CD, Rocco MV, Hicks PJ, Murea M, Ma L, Bowden DW, Freedman BI. Gene-gene interactions in APOL1-associated nephropathy. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 29: 587-94. PMID 24157943 DOI: 10.1093/Ndt/Gft423  0.543
2014 Freedman BI, Bowden DW, Smith SC, Xu J, Divers J. Relationships between electrochemical skin conductance and kidney disease in Type 2 diabetes. Journal of Diabetes and Its Complications. 28: 56-60. PMID 24140119 DOI: 10.1016/J.Jdiacomp.2013.09.006  0.417
2014 Goodarzi MO, Langefeld CD, Xiang AH, Chen YD, Guo X, Hanley AJ, Raffel LJ, Kandeel F, Nadler JL, Buchanan TA, Norris JM, Fingerlin TE, Lorenzo C, Rewers MJ, Haffner SM, ... Bowden DW, et al. Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans. Obesity (Silver Spring, Md.). 22: 1157-64. PMID 24124113 DOI: 10.1002/Oby.20639  0.338
2014 Hellwege JN, Palmer ND, Brown WM, Ziegler JT, An SS, Guo X, Chen YI, Taylor K, Hawkins GA, Ng MCY, Speliotes EK, Lorenzo C, Norris JM, Rotter JI, Wagenknecht LE, ... ... Bowden DW, et al. Erratum to: Empirical characteristics of family-based linkage to a complex trait: the ADIPOQ region and adiponectin levels Human Genetics. 134: 215-215. DOI: 10.1007/S00439-014-1518-1  0.632
2013 Bailey JN, Lu L, Chou JW, Xu J, McWilliams DR, Howard TD, Freedman BI, Bowden DW, Langefeld CD, Palmer ND. The Role of Copy Number Variation in African Americans with Type 2 Diabetes-Associated End Stage Renal Disease. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research. 7: 61. PMID 24707315 DOI: 10.4172/1747-0862.1000061  0.544
2013 Bowden DW, Cox AJ. Diabetes: Unravelling the enigma of T2DM and cardiovascular disease. Nature Reviews. Endocrinology. 9: 632-3. PMID 24100265 DOI: 10.1038/Nrendo.2013.192  0.417
2013 Raffield LM, Cox AJ, Hsu FC, Ng MC, Langefeld CD, Carr JJ, Freedman BI, Bowden DW. Impact of HDL genetic risk scores on coronary artery calcified plaque and mortality in individuals with type 2 diabetes from the Diabetes Heart Study. Cardiovascular Diabetology. 12: 95. PMID 23799899 DOI: 10.1186/1475-2840-12-95  0.485
2013 Divers J, Núñez M, High KP, Murea M, Rocco MV, Ma L, Bowden DW, Hicks PJ, Spainhour M, Ornelles DA, Kleiboeker SB, Duncan K, Langefeld CD, Turner J, Freedman BI. JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy. Kidney International. 84: 1207-13. PMID 23677244 DOI: 10.1038/Ki.2013.173  0.419
2013 Cox AJ, Lambird JE, An SS, Register TC, Langefeld CD, Carr JJ, Freedman BI, Bowden DW. Variants in adiponectin signaling pathway genes show little association with subclinical CVD in the diabetes heart study. Obesity (Silver Spring, Md.). 21: E456-62. PMID 23670978 DOI: 10.1002/Oby.20184  0.701
2013 Hugenschmidt CE, Hsu FC, Hayasaka S, Carr JJ, Freedman BI, Nyenhuis DL, Williamson JD, Bowden DW. The influence of subclinical cardiovascular disease and related risk factors on cognition in type 2 diabetes mellitus: The DHS-Mind study. Journal of Diabetes and Its Complications. 27: 422-8. PMID 23659774 DOI: 10.1016/J.Jdiacomp.2013.04.004  0.439
2013 Cox AJ, Ng MC, Xu J, Langefeld CD, Koch KL, Dawson PA, Carr JJ, Freedman BI, Hsu FC, Bowden DW. Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study. Atherosclerosis. 229: 155-60. PMID 23642732 DOI: 10.1016/J.Atherosclerosis.2013.04.008  0.56
2013 Cox AJ, Hsu FC, Carr JJ, Freedman BI, Bowden DW. Glomerular filtration rate and albuminuria predict mortality independently from coronary artery calcified plaque in the Diabetes Heart Study. Cardiovascular Diabetology. 12: 68. PMID 23594619 DOI: 10.1186/1475-2840-12-68  0.372
2013 Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, ... ... Bowden DW, et al. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nature Genetics. 45: 690-6. PMID 23583978 DOI: 10.1038/Ng.2608  0.489
2013 Register TC, Divers J, Bowden DW, Carr JJ, Lenchik L, Wagenknecht LE, Hightower RC, Xu J, Smith SC, Hruska KA, Langefeld CD, Freedman BI. Relationships between serum adiponectin and bone density, adiposity and calcified atherosclerotic plaque in the African American-Diabetes Heart Study. The Journal of Clinical Endocrinology and Metabolism. 98: 1916-22. PMID 23543659 DOI: 10.1210/Jc.2012-4126  0.36
2013 Sandy An S, Palmer ND, Hanley AJ, Ziegler JT, Mark Brown W, Freedman BI, Register TC, Rotter JI, Guo X, Ida Chen YD, Wagenknecht LE, Langefeld CD, Bowden DW. Genetic analysis of adiponectin variation and its association with type 2 diabetes in African Americans. Obesity (Silver Spring, Md.). 21: E721-9. PMID 23512866 DOI: 10.1002/Oby.20419  0.569
2013 Ma L, Murea M, Snipes JA, Marinelarena A, Krüger J, Hicks PJ, Langberg KA, Bostrom MA, Cooke JN, Suzuki D, Babazono T, Uzu T, Tang SC, Mondal AK, Sharma NK, ... ... Bowden DW, et al. An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects. Plos One. 8: e56193. PMID 23460794 DOI: 10.1371/Journal.Pone.0056193  0.482
2013 Divers J, Wagenknecht LE, Bowden DW, Carr JJ, Hightower RC, Smith SC, Xu J, Langefeld CD, Freedman BI. Albuminuria associates with calcified atherosclerotic plaque in African Americans with diabetes. Diabetes Care. 36: e34-5. PMID 23431097 DOI: 10.2337/Dc12-1589  0.498
2013 Adams JN, Cox AJ, Freedman BI, Langefeld CD, Carr JJ, Bowden DW. Genetic analysis of haptoglobin polymorphisms with cardiovascular disease and type 2 diabetes in the Diabetes Heart Study. Cardiovascular Diabetology. 12: 31. PMID 23399657 DOI: 10.1186/1475-2840-12-31  0.572
2013 Cox AJ, Hugenschmidt CE, Wang PT, Hsu FC, Kenchaiah S, Daniel K, Langefeld CD, Freedman BI, Herrington DM, Carr JJ, Stacey B, Bowden DW. Usefulness of biventricular volume as a predictor of mortality in patients with diabetes mellitus (from the Diabetes Heart Study). The American Journal of Cardiology. 111: 1152-8. PMID 23351459 DOI: 10.1016/J.Amjcard.2012.12.044  0.403
2013 Shah SA, Herrington DM, Howard TD, Divers J, Arnett DK, Burke GL, Kao WH, Guo X, Siscovick DS, Chakravarti A, Lima JA, Psaty BM, Tomaselli GF, Rich SS, Bowden DW, et al. Associations between NOS1AP single nucleotide polymorphisms (SNPs) and QT interval duration in four racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA). Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 18: 29-40. PMID 23347024 DOI: 10.1111/Anec.12028  0.539
2013 Divers J, Palmer ND, Lu L, Register TC, Carr JJ, Hicks PJ, Hightower RC, Smith SC, Xu J, Cox AJ, Hruska KA, Bowden DW, Lewis CE, Heiss G, Province MA, et al. Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus. Circulation. Cardiovascular Genetics. 6: 97-105. PMID 23233742 DOI: 10.1161/Circgenetics.112.964114  0.563
2013 Agarwal S, Cox AJ, Herrington DM, Jorgensen NW, Xu J, Freedman BI, Carr JJ, Bowden DW. Coronary calcium score predicts cardiovascular mortality in diabetes: diabetes heart study. Diabetes Care. 36: 972-7. PMID 23230101 DOI: 10.2337/Dc12-1548  0.365
2013 Ng MC, Saxena R, Li J, Palmer ND, Dimitrov L, Xu J, Rasmussen-Torvik LJ, Zmuda JM, Siscovick DS, Patel SR, Crook ED, Sims M, Chen YD, Bertoni AG, Li M, ... ... Bowden DW, et al. Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study. Diabetes. 62: 965-76. PMID 23193183 DOI: 10.2337/Db12-0266  0.602
2013 Cox AJ, Lehtinen AB, Xu J, Langefeld CD, Freedman BI, Carr JJ, Bowden DW. Polymorphisms in the Selenoprotein S gene and subclinical cardiovascular disease in the Diabetes Heart Study. Acta Diabetologica. 50: 391-9. PMID 23161441 DOI: 10.1007/S00592-012-0440-Z  0.567
2013 Register TC, Hruska KA, Divers J, Bowden DW, Palmer ND, Carr JJ, Wagenknecht LE, Hightower RC, Xu J, Smith SC, Dietzen DJ, Langefeld CD, Freedman BI. Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes. The Journal of Clinical Endocrinology and Metabolism. 98: E60-5. PMID 23125289 DOI: 10.1210/Jc.2012-3038  0.339
2013 An SS, Palmer ND, Hanley AJ, Ziegler JT, Brown WM, Haffner SM, Norris JM, Rotter JI, Guo X, Chen YD, Wagenknecht LE, Langefeld CD, Bowden DW. Estimating the contributions of rare and common genetic variations and clinical measures to a model trait: adiponectin. Genetic Epidemiology. 37: 13-24. PMID 23032297 DOI: 10.1002/Gepi.21685  0.619
2013 Lipkowitz MS, Freedman BI, Langefeld CD, Comeau ME, Bowden DW, Kao WH, Astor BC, Bottinger EP, Iyengar SK, Klotman PE, Freedman RG, Zhang W, Parekh RS, Choi MJ, Nelson GW, et al. Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans. Kidney International. 83: 114-20. PMID 22832513 DOI: 10.1038/Ki.2012.263  0.436
2013 Divers J, Hugenschmidt C, Sink KM, Williamson JD, Ge Y, Smith SC, Bowden DW, Whitlow CT, Lyders E, Maldjian JA, Freedman BI. Cerebral white matter hyperintensity in African Americans and European Americans with type 2 diabetes. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 22: e46-52. PMID 22608346 DOI: 10.1016/J.Jstrokecerebrovasdis.2012.03.019  0.435
2012 Murea M, Register TC, Divers J, Bowden DW, Carr JJ, Hightower CR, Xu J, Smith SC, Hruska KA, Langefeld CD, Freedman BI. Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study. Bmc Nephrology. 13: 148. PMID 23151275 DOI: 10.1186/1471-2369-13-148  0.419
2012 Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, et al. Informed conditioning on clinical covariates increases power in case-control association studies. Plos Genetics. 8: e1003032. PMID 23144628 DOI: 10.1371/Journal.Pgen.1003032  0.359
2012 An SS, Hanley AJ, Ziegler JT, Brown WM, Haffner SM, Norris JM, Rotter JI, Guo X, Chen YD, Wagenknecht LE, Langefeld CD, Bowden DW, Palmer ND. Association between ADIPOQ SNPs with plasma adiponectin and glucose homeostasis and adiposity phenotypes in the IRAS Family Study. Molecular Genetics and Metabolism. 107: 721-8. PMID 23102667 DOI: 10.1016/J.Ymgme.2012.10.003  0.669
2012 Bostrom MA, Perlegas P, Lu L, Hicks PJ, Hawkins G, Ng MC, Langefeld CD, Freedman BI, Bowden DW. Relevance of the ACTN4 gene in African-Americans with non-diabetic end-stage renal disease. American Journal of Nephrology. 36: 252-60. PMID 22965004 DOI: 10.1159/000342205  0.572
2012 Liu CT, Ng MC, Rybin D, Adeyemo A, Bielinski SJ, Boerwinkle E, Borecki I, Cade B, Chen YD, Djousse L, Fornage M, Goodarzi MO, Grant SF, Guo X, Harris T, ... ... Bowden DW, et al. Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. Diabetologia. 55: 2970-84. PMID 22893027 DOI: 10.1007/S00125-012-2656-4  0.537
2012 Bowden DW, Freedman BI. The challenging search for diabetic nephropathy genes. Diabetes. 61: 1923-4. PMID 22826311 DOI: 10.2337/Db12-0596  0.427
2012 Freedman BI, Langefeld CD, Turner J, Núñez M, High KP, Spainhour M, Hicks PJ, Bowden DW, Reeves-Daniel AM, Murea M, Rocco MV, Divers J. Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease. Kidney International. 82: 805-11. PMID 22695330 DOI: 10.1038/Ki.2012.217  0.47
2012 Rasmussen-Torvik LJ, Guo X, Bowden DW, Bertoni AG, Sale MM, Yao J, Bluemke DA, Goodarzi MO, Chen YI, Vaidya D, Raffel LJ, Papanicolaou GJ, Meigs JB, Pankow JS. Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA). Genetic Epidemiology. 36: 384-91. PMID 22508271 DOI: 10.1002/Gepi.21632  0.485
2012 Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, ... ... Bowden DW, et al. Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. American Journal of Human Genetics. 90: 410-25. PMID 22325160 DOI: 10.1016/J.Ajhg.2011.12.022  0.544
2012 Cooke JN, Ng MC, Palmer ND, An SS, Hester JM, Freedman BI, Langefeld CD, Bowden DW. Genetic risk assessment of type 2 diabetes-associated polymorphisms in African Americans. Diabetes Care. 35: 287-92. PMID 22275441 DOI: 10.2337/Dc11-0957  0.834
2012 Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, Ferrara A, ... ... Bowden DW, et al. A genome-wide association search for type 2 diabetes genes in African Americans. Plos One. 7: e29202. PMID 22238593 DOI: 10.1371/Journal.Pone.0029202  0.844
2012 Cox AJ, Agarwal S, M Herrington D, Carr JJ, Freedman BI, Bowden DW. C-reactive protein concentration predicts mortality in type 2 diabetes: The Diabetes Heart Study Diabetic Medicine. 29: 767-770. PMID 22211818 DOI: 10.1111/J.1464-5491.2011.03560.X  0.412
2012 Bostrom MA, Kao WH, Li M, Abboud HE, Adler SG, Iyengar SK, Kimmel PL, Hanson RL, Nicholas SB, Rasooly RS, Sedor JR, Coresh J, Kohn OF, Leehey DJ, Thornley-Brown D, ... ... Bowden DW, et al. Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 59: 210-21. PMID 22119407 DOI: 10.1053/J.Ajkd.2011.09.020  0.571
2012 Walford GA, Green T, Neale B, Isakova T, Rotter JI, Grant SF, Fox CS, Pankow JS, Wilson JG, Meigs JB, Siscovick DS, Bowden DW, Daly MJ, Florez JC. Common genetic variants differentially influence the transition from clinically defined states of fasting glucose metabolism. Diabetologia. 55: 331-9. PMID 22038522 DOI: 10.1007/S00125-011-2353-8  0.396
2012 Cooke JN, Bostrom MA, Hicks PJ, Ng MC, Hellwege JN, Comeau ME, Divers J, Langefeld CD, Freedman BI, Bowden DW. Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 27: 1505-11. PMID 21968013 DOI: 10.1093/Ndt/Gfr522  0.782
2012 Hester JM, Wing MR, Li J, Palmer ND, Xu J, Hicks PJ, Roh BH, Norris JM, Wagenknecht LE, Langefeld CD, Freedman BI, Bowden DW, Ng MC. Implication of European-derived adiposity loci in African Americans. International Journal of Obesity (2005). 36: 465-73. PMID 21750520 DOI: 10.1038/Ijo.2011.131  0.851
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2012 Ng MC, Hester JM, Wing MR, Li J, Xu J, Hicks PJ, Roh BH, Lu L, Divers J, Langefeld CD, Freedman BI, Palmer ND, Bowden DW. Genome-wide association of BMI in African Americans. Obesity (Silver Spring, Md.). 20: 622-7. PMID 21701570 DOI: 10.1038/Oby.2011.154  0.854
2012 Rao M, Mottl AK, Cole SA, Umans JG, Freedman BI, Bowden DW, Langefeld CD, Fox CS, Yang Q, Cupples A, Iyengar SK, Hunt SC, Trikalinos TA. Meta-analysis of genome-wide linkage scans for renal function traits. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 27: 647-56. PMID 21622988 DOI: 10.1093/Ndt/Gfr255  0.396
2012 Bowden DW. Association of the PTPN1 gene with type 2 diabetes and insulin resistance. Discovery Medicine. 4: 427-32. PMID 20704943  0.306
2012 Saxena R, Elbers C, Guo Y, Peter I, Gaunt T, Mega J, Lanktree M, Tare A, Castillo B, Li Y, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight B, ... ... Bowden D, et al. Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci The American Journal of Human Genetics. 90: 753. DOI: 10.1016/J.Ajhg.2012.03.001  0.43
2011 Hellwege JN, Hicks PJ, Palmer ND, Ng MC, Freedman BI, Bowden DW. Examination of Rare Variants in HNF4 α in European Americans with Type 2 Diabetes. Journal of Diabetes & Metabolism. 2. PMID 23227446 DOI: 10.4172/2155-6156.1000145  0.753
2011 Freedman BI, Bowden DW. Risk factors: Race, renal disease and albuminuria. Nature Reviews. Nephrology. 7: 679-80. PMID 22009246 DOI: 10.1038/Nrneph.2011.154  0.353
2011 Freedman BI, Langefeld CD, Murea M, Ma L, Otvos JD, Turner J, Antinozzi PA, Divers J, Hicks PJ, Bowden DW, Rocco MV, Parks JS. Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 26: 3805-10. PMID 21931123 DOI: 10.1093/Ndt/Gfr542  0.443
2011 Hicks PJ, Langefeld CD, Lu L, Bleyer AJ, Divers J, Nachman PH, Derebail VK, Bowden DW, Freedman BI. Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans. Kidney International. 80: 1339-43. PMID 21849968 DOI: 10.1038/Ki.2011.286  0.515
2011 Freedman BI, Langefeld CD, Lu L, Divers J, Comeau ME, Kopp JB, Winkler CA, Nelson GW, Johnson RC, Palmer ND, Hicks PJ, Bostrom MA, Cooke JN, McDonough CW, Bowden DW. Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans. Plos Genetics. 7: e1002150. PMID 21698141 DOI: 10.1371/Journal.Pgen.1002150  0.766
2011 Cox AJ, Wing MR, Carr JJ, Hightower RC, Smith SC, Xu J, Wagenknecht LE, Bowden DW, Freedman BI. Association of PNPLA3 SNP rs738409 with liver density in African Americans with type 2 diabetes mellitus. Diabetes & Metabolism. 37: 452-5. PMID 21665509 DOI: 10.1016/J.Diabet.2011.05.001  0.764
2011 Mathias RA, Sergeant S, Ruczinski I, Torgerson DG, Hugenschmidt CE, Kubala M, Vaidya D, Suktitipat B, Ziegler JT, Ivester P, Case D, Yanek LR, Freedman BI, Rudock ME, Barnes KC, ... ... Bowden DW, et al. The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans. Bmc Genetics. 12: 50. PMID 21599946 DOI: 10.1186/1471-2156-12-50  0.459
2011 Murea M, Lu L, Ma L, Hicks PJ, Divers J, McDonough CW, Langefeld CD, Bowden DW, Freedman BI. Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. American Journal of Nephrology. 33: 502-9. PMID 21546767 DOI: 10.1159/000327985  0.738
2011 Reeves-Daniel AM, DePalma JA, Bleyer AJ, Rocco MV, Murea M, Adams PL, Langefeld CD, Bowden DW, Hicks PJ, Stratta RJ, Lin JJ, Kiger DF, Gautreaux MD, Divers J, Freedman BI. The APOL1 gene and allograft survival after kidney transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 11: 1025-30. PMID 21486385 DOI: 10.1111/J.1600-6143.2011.03513.X  0.338
2011 Igo RP, Iyengar SK, Nicholas SB, Goddard KA, Langefeld CD, Hanson RL, Duggirala R, Divers J, Abboud H, Adler SG, Arar NH, Horvath A, Elston RC, Bowden DW, Guo X, et al. Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study. American Journal of Nephrology. 33: 381-9. PMID 21454968 DOI: 10.1159/000326763  0.516
2011 Divers J, Register TC, Langefeld CD, Wagenknecht LE, Bowden DW, Carr JJ, Hightower RC, Xu J, Hruska KA, Freedman BI. Relationships between calcified atherosclerotic plaque and bone mineral density in African Americans with type 2 diabetes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1554-60. PMID 21437982 DOI: 10.1002/Jbmr.389  0.376
2011 Agarwal S, Morgan T, Herrington DM, Xu J, Cox AJ, Freedman BI, Carr JJ, Bowden DW. Coronary calcium score and prediction of all-cause mortality in diabetes: the diabetes heart study. Diabetes Care. 34: 1219-24. PMID 21398528 DOI: 10.2337/Dc11-0008  0.355
2011 Lettre G, Palmer CD, Young T, Ejebe KG, Allayee H, Benjamin EJ, Bennett F, Bowden DW, Chakravarti A, Dreisbach A, Farlow DN, Folsom AR, Fornage M, Forrester T, Fox E, et al. Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. Plos Genetics. 7: e1001300. PMID 21347282 DOI: 10.1371/Journal.Pgen.1001300  0.514
2011 Lehtinen AB, Cox AJ, Ziegler JT, Voruganti VS, Xu J, Freedman BI, Carr JJ, Comuzzie AG, Langefeld CD, Bowden DW. Genetic mapping of vascular calcified plaque loci on chromosome 16p in European Americans from the diabetes heart study. Annals of Human Genetics. 75: 222-35. PMID 21309755 DOI: 10.1111/J.1469-1809.2010.00632.X  0.567
2011 Wagenknecht LE, Palmer ND, Bowden DW, Rotter JI, Norris JM, Ziegler J, Chen YD, Haffner S, Scherzinger A, Langefeld CD. Association of PNPLA3 with non-alcoholic fatty liver disease in a minority cohort: the Insulin Resistance Atherosclerosis Family Study. Liver International : Official Journal of the International Association For the Study of the Liver. 31: 412-6. PMID 21281435 DOI: 10.1111/J.1478-3231.2010.02444.X  0.468
2011 Sibbel SP, Talbert ME, Bowden DW, Haffner SM, Taylor KD, Chen YD, Wagenknecht LE, Langefeld CD, Norris JM. RGS6 variants are associated with dietary fat intake in Hispanics: the IRAS Family Study. Obesity (Silver Spring, Md.). 19: 1433-8. PMID 21233807 DOI: 10.1038/Oby.2010.333  0.81
2011 McDonough CW, Palmer ND, Hicks PJ, Roh BH, An SS, Cooke JN, Hester JM, Wing MR, Bostrom MA, Rudock ME, Lewis JP, Talbert ME, Blevins RA, Lu L, Ng MC, ... ... Bowden DW, et al. A genome-wide association study for diabetic nephropathy genes in African Americans. Kidney International. 79: 563-72. PMID 21150874 DOI: 10.1038/Ki.2010.467  0.83
2011 Freedman BI, Bowden DW, Murea M. Protein kinase C-β gene variants and type 2 diabetes-associated kidney failure: What can we learn from gene association studies in diabetic nephropathy? American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 57: 194-7. PMID 21146268 DOI: 10.1053/J.Ajkd.2010.10.042  0.538
2011 Wagenknecht LE, Divers J, Bertoni AG, Langefeld CD, Carr JJ, Bowden DW, Elbein SC, Shea S, Lewis CE, Freedman BI. Correlates of coronary artery calcified plaque in blacks and whites with type 2 diabetes. Annals of Epidemiology. 21: 34-41. PMID 21130367 DOI: 10.1016/J.Annepidem.2010.10.007  0.418
2011 Wing MR, Ziegler JM, Langefeld CD, Roh BH, Palmer ND, Mayer-Davis EJ, Rewers MJ, Haffner SM, Wagenknecht LE, Bowden DW. Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort. International Journal of Obesity (2005). 35: 1173-82. PMID 21102551 DOI: 10.1038/Ijo.2010.244  0.786
2011 Gopalakrishnan I, Iskandar SS, Daeihagh P, Divers J, Langefeld CD, Bowden DW, Hicks PJ, Rocco MV, Freedman BI. Coincident idiopathic focal segmental glomerulosclerosis collapsing variant and diabetic nephropathy in an African American homozygous for MYH9 risk variants. Human Pathology. 42: 291-4. PMID 21074826 DOI: 10.1016/J.Humpath.2010.07.016  0.502
2011 Palmer ND, Hester JM, An SS, Adeyemo A, Rotimi C, Langefeld CD, Freedman BI, Ng MC, Bowden DW. Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant. Diabetes. 60: 662-8. PMID 20980453 DOI: 10.2337/Db10-0134  0.869
2011 Anderson AH, Chen J, Gadebegku CA, Feldman HI, Fink JC, Go AS, Joffe M, Nessel LA, Ojo A, Rader DJ, Reilly MP, Teal V, Teff K, Wright JT, Xie D, ... ... Bowden DW, et al. Contents Vol. 33, 2011 American Journal of Nephrology. 33. DOI: 10.1159/000329531  0.546
2011 Rudock ME, Cox AJ, Ziegler JT, Lehtinen AB, Connelly JJ, Freedman BI, Carr JJ, Langefeld CD, Hauser ER, Horne BD, Bowden DW. Cigarette smoking status has a modifying effect on the association between polymorphisms in KALRN and measures of cardiovascular risk in the diabetes heart study Genes and Genomics. 33: 483-490. DOI: 10.1007/S13258-011-0069-2  0.455
2011 Bowden DW. Will family studies return to prominence in human genetics and genomics? Rare variants and linkage analysis of complex traits Genes and Genomics. 33: 1-8. DOI: 10.1007/S13258-011-0002-8  0.36
2010 Bowden DW, Cox AJ, Freedman BI, Hugenschimdt CE, Wagenknecht LE, Herrington D, Agarwal S, Register TC, Maldjian JA, Ng MC, Hsu FC, Langefeld CD, Williamson JD, Carr JJ. Review of the Diabetes Heart Study (DHS) family of studies: a comprehensively examined sample for genetic and epidemiological studies of type 2 diabetes and its complications. The Review of Diabetic Studies : Rds. 7: 188-201. PMID 21409311 DOI: 10.1900/RDS.2010.7.188  0.376
2010 Divers J, Wagenknecht LE, Bowden DW, Carr JJ, Hightower RC, Register TC, Xu J, Langefeld CD, Freedman BI. Ethnic differences in the relationship between pericardial adipose tissue and coronary artery calcified plaque: African-American-diabetes heart study. The Journal of Clinical Endocrinology and Metabolism. 95: 5382-9. PMID 20810573 DOI: 10.1210/Jc.2010-0793  0.399
2010 Freedman BI, Kopp JB, Langefeld CD, Genovese G, Friedman DJ, Nelson GW, Winkler CA, Bowden DW, Pollak MR. The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans. Journal of the American Society of Nephrology : Jasn. 21: 1422-6. PMID 20688934 DOI: 10.1681/Asn.2010070730  0.503
2010 Bowden DW, An SS, Palmer ND, Brown WM, Norris JM, Haffner SM, Hawkins GA, Guo X, Rotter JI, Chen YD, Wagenknecht LE, Langefeld CD. Molecular basis of a linkage peak: exome sequencing and family-based analysis identify a rare genetic variant in the ADIPOQ gene in the IRAS Family Study. Human Molecular Genetics. 19: 4112-20. PMID 20688759 DOI: 10.1093/Hmg/Ddq327  0.599
2010 Lewis JP, Palmer ND, Ellington JB, Divers J, Ng MC, Lu L, Langefeld CD, Freedman BI, Bowden DW. Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans. Genomics. 96: 211-9. PMID 20650312 DOI: 10.1016/J.Ygeno.2010.07.006  0.57
2010 Genovese G, Friedman DJ, Ross MD, Lecordier L, Uzureau P, Freedman BI, Bowden DW, Langefeld CD, Oleksyk TK, Uscinski Knob AL, Bernhardy AJ, Hicks PJ, Nelson GW, Vanhollebeke B, Winkler CA, et al. Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science (New York, N.Y.). 329: 841-5. PMID 20647424 DOI: 10.1126/Science.1193032  0.419
2010 Engelman CD, Meyers KJ, Ziegler JT, Taylor KD, Palmer ND, Haffner SM, Fingerlin TE, Wagenknecht LE, Rotter JI, Bowden DW, Langefeld CD, Norris JM. Genome-wide association study of vitamin D concentrations in Hispanic Americans: the IRAS family study. The Journal of Steroid Biochemistry and Molecular Biology. 122: 186-92. PMID 20600896 DOI: 10.1016/J.Jsbmb.2010.06.013  0.438
2010 Burdon KP, Rudock ME, Lehtinen AB, Langefeld CD, Bowden DW, Register TC, Liu Y, Freedman BI, Carr JJ, Hedrick CC, Rich SS. Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study. Mediators of Inflammation. 2010: 170153. PMID 20592751 DOI: 10.1155/2010/170153  0.552
2010 Bostrom MA, Lu L, Chou J, Hicks PJ, Xu J, Langefeld CD, Bowden DW, Freedman BI. Candidate genes for non-diabetic ESRD in African Americans: a genome-wide association study using pooled DNA. Human Genetics. 128: 195-204. PMID 20532800 DOI: 10.1007/S00439-010-0842-3  0.535
2010 Freedman BI, Edberg JC, Comeau ME, Murea M, Bowden DW, Divers J, Alarcón GS, Brown EE, McGwin G, Kopp JB, Winkler CA, Nelson GW, Illei G, Petri M, Ramsey-Goldman R, et al. The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans. American Journal of Nephrology. 32: 66-72. PMID 20523037 DOI: 10.1159/000314688  0.511
2010 Tang SC, Leung VT, Chan LY, Wong SS, Chu DW, Leung JC, Ho YW, Lai KN, Ma L, Elbein SC, Bowden DW, Hicks PJ, Comeau ME, Langefeld CD, Freedman BI. The acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with nephropathy in Chinese patients with type 2 diabetes. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 25: 3931-4. PMID 20519229 DOI: 10.1093/Ndt/Gfq303  0.529
2010 Chen Y, Lipkowitz MS, Salem RM, Fung MM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Hicks PJ, Bowden DW, Freedman BI, Brophy VH, O'Connor DT, et al. Progression of chronic kidney disease: Adrenergic genetic influence on glomerular filtration rate decline in hypertensive nephrosclerosis. American Journal of Nephrology. 32: 23-30. PMID 20484896 DOI: 10.1159/000313927  0.377
2010 Bostrom MA, Hicks PJ, Lu L, Langefeld CD, Freedman BI, Bowden DW. Association of polymorphisms in the klotho gene with severity of non-diabetic ESRD in African Americans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 25: 3348-55. PMID 20466664 DOI: 10.1093/Ndt/Gfq214  0.545
2010 Divers J, Wagenknecht LE, Bowden DW, Carr JJ, Hightower RC, Ding J, Xu J, Langefeld CD, Freedman BI. Regional adipose tissue associations with calcified atherosclerotic plaque: African American-diabetes heart study. Obesity (Silver Spring, Md.). 18: 2004-9. PMID 20186134 DOI: 10.1038/Oby.2010.30  0.416
2010 Doran AC, Lehtinen AB, Meller N, Lipinski MJ, Slayton RP, Oldham SN, Skaflen MD, Yeboah J, Rich SS, Bowden DW, McNamara CA. Id3 is a novel atheroprotective factor containing a functionally significant single-nucleotide polymorphism associated with intima-media thickness in humans. Circulation Research. 106: 1303-11. PMID 20185798 DOI: 10.1161/Circresaha.109.210294  0.39
2010 Maeda S, Kobayashi MA, Araki S, Babazono T, Freedman BI, Bostrom MA, Cooke JN, Toyoda M, Umezono T, Tarnow L, Hansen T, Gaede P, Jorsal A, Ng DP, Ikeda M, ... ... Bowden DW, et al. A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes. Plos Genetics. 6: e1000842. PMID 20168990 DOI: 10.1371/Journal.Pgen.1000842  0.57
2010 Leak TS, Langefeld CD, Keene KL, Gallagher CJ, Lu L, Mychaleckyj JC, Rich SS, Freedman BI, Bowden DW, Sale MM. Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy. Bmc Medical Genetics. 11: 22. PMID 20144192 DOI: 10.1186/1471-2350-11-22  0.8
2010 Nelson GW, Freedman BI, Bowden DW, Langefeld CD, An P, Hicks PJ, Bostrom MA, Johnson RC, Kopp JB, Winkler CA. Dense mapping of MYH9 localizes the strongest kidney disease associations to the region of introns 13 to 15. Human Molecular Genetics. 19: 1805-15. PMID 20124285 DOI: 10.1093/Hmg/Ddq039  0.523
2010 Reeves-Daniel AM, Iskandar SS, Bowden DW, Bostrom MA, Hicks PJ, Comeau ME, Langefeld CD, Freedman BI. Is collapsing C1q nephropathy another MYH9-associated kidney disease? A case report. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 55: e21-4. PMID 20116156 DOI: 10.1053/J.Ajkd.2009.10.060  0.429
2010 Palmer ND, Mychaleckyj JC, Langefeld CD, Ziegler JT, Williams AH, Bryer-Ash M, Bowden DW. Evaluation of DLG2 as a positional candidate for disposition index in African-Americans from the IRAS Family Study. Diabetes Research and Clinical Practice. 87: 69-76. PMID 19931931 DOI: 10.1016/J.Diabres.2009.10.015  0.343
2010 Palmer ND, Langefeld CD, Ziegler JT, Hsu F, Haffner SM, Fingerlin T, Norris JM, Chen YI, Rich SS, Haritunians T, Taylor KD, Bergman RN, Rotter JI, Bowden DW. Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study. Diabetologia. 53: 281-9. PMID 19902172 DOI: 10.1007/S00125-009-1586-2  0.422
2010 Divers J, Wagenknecht LE, Bowden DW, Carr JJ, Hightower RC, Xu J, Langefeld CD, Freedman BI. Ethnic differences in the relationship between albuminuria and calcified atherosclerotic plaque: the African American-diabetes heart study. Diabetes Care. 33: 131-8. PMID 19825824 DOI: 10.2337/Dc09-1253  0.41
2010 Miller MR, Zhang W, Sibbel SP, Langefeld CD, Bowden DW, Haffner SM, Bergman RN, Norris JM, Fingerlin TE. Variant in the 3' region of the IkappaBalpha gene associated with insulin resistance in Hispanic Americans: The IRAS Family Study. Obesity (Silver Spring, Md.). 18: 555-62. PMID 19798070 DOI: 10.1038/Oby.2009.303  0.479
2010 Brumbaugh D, Sibbel S, Fingerlin T, Bowden D, Wagenknecht L, Fang-Chi H, Ida Chen Y, Guo X, Rotter JI, Haffner S, Norris J. M1991 Association of a Variant in the Adiponectin Gene With Liver Enzyme Levels in Hispanic-Americans: The IRAS Family Study Gastroenterology. 138: S-454. DOI: 10.1016/S0016-5085(10)62100-2  0.347
2009 Malhotra A, Igo RP, Thameem F, Kao WH, Abboud HE, Adler SG, Arar NH, Bowden DW, Duggirala R, Freedman BI, Goddard KA, Ipp E, Iyengar SK, Kimmel PL, Knowler WC, et al. Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group. Diabetes/Metabolism Research and Reviews. 25: 740-7. PMID 19795399 DOI: 10.1002/Dmrr.1031  0.475
2009 Freedman BI, Nagaraj SK, Lin JJ, Gautreaux MD, Bowden DW, Iskandar SS, Stratta RJ, Rogers J, Hartmann EL, Farney AC, Reeves-Daniel AM. Potential donor-recipient MYH9 genotype interactions in posttransplant nephrotic syndrome after pediatric kidney transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9: 2435-40. PMID 19764949 DOI: 10.1111/J.1600-6143.2009.02806.X  0.346
2009 McDonough CW, Bostrom MA, Lu L, Hicks PJ, Langefeld CD, Divers J, Mychaleckyj JC, Freedman BI, Bowden DW. Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping. Human Genetics. 126: 805-17. PMID 19690890 DOI: 10.1007/S00439-009-0732-8  0.768
2009 Freedman BI, Hicks PJ, Bostrom MA, Comeau ME, Divers J, Bleyer AJ, Kopp JB, Winkler CA, Nelson GW, Langefeld CD, Bowden DW. Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 24: 3366-71. PMID 19567477 DOI: 10.1093/Ndt/Gfp316  0.489
2009 Norris JM, Langefeld CD, Talbert ME, Wing MR, Haritunians T, Fingerlin TE, Hanley AJ, Ziegler JT, Taylor KD, Haffner SM, Chen YD, Bowden DW, Wagenknecht LE. Genome-wide association study and follow-up analysis of adiposity traits in Hispanic Americans: the IRAS Family Study. Obesity (Silver Spring, Md.). 17: 1932-41. PMID 19461586 DOI: 10.1038/Oby.2009.143  0.842
2009 Freedman BI, Bowden DW, Ziegler JT, Langefeld CD, Lehtinen AB, Rudock ME, Lenchik L, Hruska KA, Register TC, Carr JJ. Bone morphogenetic protein 7 (BMP7) gene polymorphisms are associated with inverse relationships between vascular calcification and BMD: the Diabetes Heart Study. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1719-27. PMID 19453255 DOI: 10.1359/Jbmr.090501  0.516
2009 Schmitz KJ, Skinner HG, Bautista LE, Fingerlin TE, Langefeld CD, Hicks PJ, Haffner SM, Bryer-Ash M, Wagenknecht LE, Bowden DW, Norris JM, Engelman CD. Association of 25-hydroxyvitamin D with blood pressure in predominantly 25-hydroxyvitamin D deficient Hispanic and African Americans. American Journal of Hypertension. 22: 867-70. PMID 19444222 DOI: 10.1038/Ajh.2009.88  0.331
2009 Rich SS, Goodarzi MO, Palmer ND, Langefeld CD, Ziegler J, Haffner SM, Bryer-Ash M, Norris JM, Taylor KD, Haritunians T, Rotter JI, Chen YD, Wagenknecht LE, Bowden DW, Bergman RN. A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS). Diabetologia. 52: 1326-33. PMID 19430760 DOI: 10.1007/S00125-009-1373-0  0.388
2009 McDonough CW, Hicks PJ, Lu L, Langefeld CD, Freedman BI, Bowden DW. The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-Americans. Human Genetics. 126: 265-75. PMID 19373489 DOI: 10.1007/S00439-009-0667-0  0.758
2009 Talbert ME, Langefeld CD, Ziegler JT, Haffner SM, Norris JM, Bowden DW. INSIG2 SNPs associated with obesity and glucose homeostasis traits in Hispanics: the IRAS Family Study. Obesity (Silver Spring, Md.). 17: 1554-62. PMID 19360016 DOI: 10.1038/Oby.2009.94  0.835
2009 Sutton BS, Palmer ND, Langefeld CD, Xue B, Proctor A, Ziegler JT, Haffner SM, Norris JM, Bowden DW. Association of SSTR2 polymorphisms and glucose homeostasis phenotypes: the Insulin Resistance Atherosclerosis Family Study. Diabetes. 58: 1457-62. PMID 19324939 DOI: 10.2337/Db08-0189  0.768
2009 Wing MR, Ziegler J, Langefeld CD, Ng MC, Haffner SM, Norris JM, Goodarzi MO, Bowden DW. Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study. Human Genetics. 125: 615-26. PMID 19322589 DOI: 10.1007/S00439-009-0656-3  0.784
2009 Bleyer AJ, Hire D, Russell GB, Xu J, Divers J, Shihabi Z, Bowden DW, Freedman BI. Ethnic variation in the correlation between random serum glucose concentration and glycated haemoglobin: Original Article: Metabolism Diabetic Medicine. 26: 128-133. PMID 19236614 DOI: 10.1111/J.1464-5491.2008.02646.X  0.343
2009 Leak TS, Perlegas PS, Smith SG, Keene KL, Hicks PJ, Langefeld CD, Mychaleckyj JC, Rich SS, Kirk JK, Freedman BI, Bowden DW, Sale MM. Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans. Annals of Human Genetics. 73: 152-9. PMID 19183347 DOI: 10.1111/J.1469-1809.2008.00498.X  0.798
2009 Freedman BI, Hicks PJ, Bostrom MA, Cunningham ME, Liu Y, Divers J, Kopp JB, Winkler CA, Nelson GW, Langefeld CD, Bowden DW. Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans. Kidney International. 75: 736-45. PMID 19177153 DOI: 10.1038/Ki.2008.701  0.508
2009 Lehtinen AB, Daniel KR, Shah SA, Nelson MR, Ziegler JT, Freedman BI, Carr JJ, Herrington DM, Langefeld CD, Bowden DW. Relationship between genetic variants in myocardial sodium and potassium channel genes and QT interval duration in diabetics: the Diabetes Heart Study. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 14: 72-9. PMID 19149796 DOI: 10.1111/J.1542-474X.2008.00276.X  0.45
2009 Friedman DJ, Talbert ME, Bowden DW, Freedman BI, Mukanya Y, Enjyoji K, Robson SC. Functional ENTPD1 polymorphisms in African Americans with diabetes and end-stage renal disease. Diabetes. 58: 999-1006. PMID 19095759 DOI: 10.2337/Db08-1214  0.845
2009 Talbert ME, Langefeld CD, Ziegler J, Mychaleckyj JC, Haffner SM, Norris JM, Bowden DW. Polymorphisms near SOCS3 are associated with obesity and glucose homeostasis traits in Hispanic Americans from the Insulin Resistance Atherosclerosis Family Study. Human Genetics. 125: 153-62. PMID 19083014 DOI: 10.1007/S00439-008-0608-3  0.845
2009 Bostrom MA, Freedman BI, Langefeld CD, Liu L, Hicks PJ, Bowden DW. Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy. Diabetes. 58: 499-504. PMID 19056609 DOI: 10.2337/Db08-0598  0.503
2009 Zhang D, Freedman BI, Flekac M, Santos E, Hicks PJ, Bowden DW, Efendic S, Brismar K, Gu HF. Evaluation of genetic association and expression reduction of TRPC1 in the development of diabetic nephropathy. American Journal of Nephrology. 29: 244-51. PMID 18802326 DOI: 10.1159/000157627  0.447
2009 Rudock ME, Liu Y, Ziegler JT, Allen SG, Lehtinen AB, Freedman BI, Carr JJ, Langefeld CD, Bowden DW. Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study Atherosclerosis. 203: 459-465. PMID 18768181 DOI: 10.1016/J.Atherosclerosis.2008.07.018  0.55
2009 Bowden D, Allred N, Langefeld C, Divers J, Freedman B, Ng M. Genome wide and candidate gene studies of African American type 2 diabetes Canadian Journal of Diabetes. 33: 193-194. DOI: 10.1016/S1499-2671(09)33034-8  0.468
2008 McKimmie RL, Daniel KR, Carr JJ, Bowden DW, Freedman BI, Register TC, Hsu FC, Lohman KK, Weinberg RB, Wagenknecht LE. Hepatic steatosis and subclinical cardiovascular disease in a cohort enriched for type 2 diabetes: the Diabetes Heart Study. The American Journal of Gastroenterology. 103: 3029-35. PMID 18853970 DOI: 10.1111/J.1572-0241.2008.02188.X  0.4
2008 Palmer ND, Langefeld CD, Bryer-Ash M, Rotter JI, Taylor KD, Bowden DW. Association of the Kir6.2 E23K variant with reduced acute insulin response in African-Americans. The Journal of Clinical Endocrinology and Metabolism. 93: 4979-83. PMID 18796522 DOI: 10.1210/Jc.2008-0543  0.346
2008 Kopp JB, Smith MW, Nelson GW, Johnson RC, Freedman BI, Bowden DW, Oleksyk T, McKenzie LM, Kajiyama H, Ahuja TS, Berns JS, Briggs W, Cho ME, Dart RA, Kimmel PL, et al. MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis. Nature Genetics. 40: 1175-84. PMID 18794856 DOI: 10.1038/Ng.226  0.524
2008 Arar NH, Freedman BI, Adler SG, Iyengar SK, Chew EY, Davis MD, Satko SG, Bowden DW, Duggirala R, Elston RC, Guo X, Hanson RL, Igo RP, Ipp E, Kimmel PL, et al. Heritability of the severity of diabetic retinopathy: the FIND-Eye study. Investigative Ophthalmology & Visual Science. 49: 3839-45. PMID 18765632 DOI: 10.1167/Iovs.07-1633  0.433
2008 Keene KL, Mychaleckyj JC, Leak TS, Smith SG, Perlegas PS, Divers J, Langefeld CD, Freedman BI, Bowden DW, Sale MM. Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease. Human Genetics. 124: 147-54. PMID 18654799 DOI: 10.1007/S00439-008-0532-6  0.738
2008 Liu Y, Freedman BI, Burdon KP, Langefeld CD, Howard T, Herrington D, Goff DC, Bowden DW, Wagenknecht LE, Hedrick CC, Rich SS. Association of arachidonate 12-lipoxygenase genotype variation and glycemic control with albuminuria in type 2 diabetes. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 52: 242-50. PMID 18640486 DOI: 10.1053/J.Ajkd.2007.12.033  0.391
2008 Bento JL, Palmer ND, Zhong M, Roh B, Lewis JP, Wing MR, Pandya H, Freedman BI, Langefeld CD, Rich SS, Bowden DW, Mychaleckyj JC. Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1. Genomics. 92: 226-34. PMID 18602983 DOI: 10.1016/J.Ygeno.2008.06.004  0.795
2008 Engelman CD, Fingerlin TE, Langefeld CD, Hicks PJ, Rich SS, Wagenknecht LE, Bowden DW, Norris JM. Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African Americans. The Journal of Clinical Endocrinology and Metabolism. 93: 3381-8. PMID 18593774 DOI: 10.1210/Jc.2007-2702  0.334
2008 Hicks PJ, Staten JL, Palmer ND, Langefeld CD, Ziegler JT, Keene KL, Sale MM, Bowden DW, Freedman BI. Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease. American Journal of Nephrology. 28: 914-20. PMID 18580054 DOI: 10.1159/000141934  0.801
2008 Leak TS, Mychaleckyj JC, Smith SG, Keene KL, Gordon CJ, Hicks PJ, Freedman BI, Bowden DW, Sale MM. Evaluation of a SNP map of 6q24-27 confirms diabetic nephropathy loci and identifies novel associations in type 2 diabetes patients with nephropathy from an African-American population. Human Genetics. 124: 63-71. PMID 18560894 DOI: 10.1007/S00439-008-0523-7  0.802
2008 Burdon KP, Lehtinen AB, Langefeld CD, Carr JJ, Rich SS, Freedman BI, Herrington D, Bowden DW. Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study Diabetes and Vascular Disease Research. 5: 128-134. PMID 18537101 DOI: 10.3132/Dvdr.2008.021  0.564
2008 Bowden DW, Lehtinen AB, Ziegler JT, Rudock ME, Xu J, Wagenknecht LE, Herrington DM, Rich SS, Freedman BI, Carr JJ, Langefeld CD. Genetic epidemiology of subclinical cardiovascular disease in the diabetes heart study. Annals of Human Genetics. 72: 598-610. PMID 18460048 DOI: 10.1111/J.1469-1809.2008.00446.X  0.487
2008 Lewis JP, Palmer ND, Hicks PJ, Sale MM, Langefeld CD, Freedman BI, Divers J, Bowden DW. Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies. Diabetes. 57: 2220-5. PMID 18443202 DOI: 10.2337/Db07-1319  0.554
2008 Bielinski SJ, Pankow JS, Li N, Hsu FC, Adar SD, Jenny NS, Bowden DW, Wasserman BA, Arnett D. ICAM1 and VCAM1 polymorphisms, coronary artery calcium, and circulating levels of soluble ICAM-1: the multi-ethnic study of atherosclerosis (MESA). Atherosclerosis. 201: 339-44. PMID 18420209 DOI: 10.1016/J.Atherosclerosis.2008.02.031  0.468
2008 Nelson MR, Daniel KR, Carr JJ, Freedman BI, Prineas RJ, Bowden DW, Herrington DM. Associations between electrocardiographic interval durations and coronary artery calcium scores: the Diabetes Heart Study. Pacing and Clinical Electrophysiology : Pace. 31: 314-21. PMID 18307626 DOI: 10.1111/J.1540-8159.2008.00991.X  0.347
2008 Freedman BI, Bowden DW, Rich SS, Xu J, Wagenknecht LE, Ziegler J, Hicks PJ, Langefeld CD. Genome-wide linkage scans for renal function and albuminuria in Type 2 diabetes mellitus: the Diabetes Heart Study. Diabetic Medicine : a Journal of the British Diabetic Association. 25: 268-76. PMID 18307454 DOI: 10.1111/J.1464-5491.2007.02361.X  0.438
2008 Keene KL, Mychaleckyj JC, Smith SG, Leak TS, Perlegas PS, Langefeld CD, Herrington DM, Freedman BI, Rich SS, Bowden DW, Sale MM. Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population. Human Genetics. 123: 333-41. PMID 18305958 DOI: 10.1007/S00439-008-0482-Z  0.797
2008 Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW. Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes. 57: 1093-100. PMID 18252897 DOI: 10.2337/Db07-1169  0.499
2008 Salem RM, Cadman PE, Chen Y, Rao F, Wen G, Hamilton BA, Rana BK, Smith DW, Stridsberg M, Ward HJ, Mahata M, Mahata SK, Bowden DW, Hicks PJ, Freedman BI, et al. Chromogranin A polymorphisms are associated with hypertensive renal disease. Journal of the American Society of Nephrology : Jasn. 19: 600-14. PMID 18235090 DOI: 10.1681/Asn.2007070754  0.403
2008 Lehtinen AB, Newton-Cheh C, Ziegler JT, Langefeld CD, Freedman BI, Daniel KR, Herrington DM, Bowden DW. Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study. Diabetes. 57: 1108-14. PMID 18235038 DOI: 10.2337/Db07-1365  0.475
2008 Keene KL, Mychaleckyj JC, Smith SG, Leak TS, Perlegas PS, Langefeld CD, Freedman BI, Rich SS, Bowden DW, Sale MM. Association of the distal region of the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene with type 2 diabetes in an African-American population enriched for nephropathy. Diabetes. 57: 1057-62. PMID 18184924 DOI: 10.2337/Db07-0886  0.807
2008 Saran AM, Hsu FC, Lohman KK, Carr JJ, Bowden DW, Wagenknecht LE, Freedman BI. Kidney volume associations with subclinical renal and cardiovascular disease: the Diabetes Heart Study. American Journal of Nephrology. 28: 366-71. PMID 18057869 DOI: 10.1159/000112226  0.425
2008 Schelling JR, Abboud HE, Nicholas SB, Pahl MV, Sedor JR, Adler SG, Arar NH, Bowden DW, Elston RC, Freedman BI, Goddard KA, Guo X, Hanson RL, Ipp E, Iyengar SK, et al. Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND). Diabetes. 57: 235-43. PMID 18003762 DOI: 10.2337/Db07-0313  0.475
2008 Palmer ND, Lehtinen AB, Langefeld CD, Campbell JK, Haffner SM, Norris JM, Bergman RN, Goodarzi MO, Rotter JI, Bowden DW. Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans. The Journal of Clinical Endocrinology and Metabolism. 93: 304-9. PMID 17971425 DOI: 10.1210/Jc.2007-1225  0.518
2008 Tsimihodimos V, Dounousi E, Siamopoulos KC, Okada T, Nakao T, Matsumoto H, Nagaoka Y, Abdelwhab S, Elshinnawy S, Hirata K, Fukagawa M, Ishida T, Nakayama K, Nakayama M, Iwabuchi M, ... ... Bowden DW, et al. Contents Vol. 28, 2008 American Journal of Nephrology. 28. DOI: 10.1159/000163081  0.613
2008 Tsimihodimos V, Dounousi E, Siamopoulos KC, Okada T, Nakao T, Matsumoto H, Nagaoka Y, Abdelwhab S, Elshinnawy S, Hirata K, Fukagawa M, Ishida T, Nakayama K, Nakayama M, Iwabuchi M, ... ... Bowden DW, et al. Subject Index Vol. 28, 2008 American Journal of Nephrology. 28: 1028-1030. DOI: 10.1159/000163080  0.618
2008 Tsimihodimos V, Dounousi E, Siamopoulos KC, Okada T, Nakao T, Matsumoto H, Nagaoka Y, Abdelwhab S, Elshinnawy S, Hirata K, Fukagawa M, Ishida T, Nakayama K, Nakayama M, Iwabuchi M, ... ... Bowden DW, et al. Consultants for the American Journal of Nephrology 2008 American Journal of Nephrology. 28: 1023-1024. DOI: 10.1159/000163076  0.658
2007 Carr JJ, Register TC, Hsu FC, Lohman K, Lenchik L, Bowden DW, Langefeld CD, Xu J, Rich SS, Wagenknecht LE, Freedman BI. Calcified atherosclerotic plaque and bone mineral density in type 2 diabetes: the diabetes heart study. Bone. 42: 43-52. PMID 17964237 DOI: 10.1016/J.Bone.2007.08.023  0.406
2007 Freedman BI, Bostrom M, Daeihagh P, Bowden DW. Genetic factors in diabetic nephropathy Clinical Journal of the American Society of Nephrology. 2: 1306-1316. PMID 17942768 DOI: 10.2215/Cjn.02560607  0.526
2007 Leak TS, Keene KL, Langefeld CD, Gallagher CJ, Mychaleckyj JC, Freedman BI, Bowden DW, Rich SS, Sale MM. Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population. Molecular Genetics and Metabolism. 92: 145-50. PMID 17618154 DOI: 10.1016/J.Ymgme.2007.05.014  0.801
2007 Sale MM, Smith SG, Mychaleckyj JC, Keene KL, Langefeld CD, Leak TS, Hicks PJ, Bowden DW, Rich SS, Freedman BI. Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy. Diabetes. 56: 2638-42. PMID 17601994 DOI: 10.2337/Db07-0012  0.803
2007 Gallagher CJ, Langefeld CD, Gordon CJ, Campbell JK, Mychaleckyj JC, Mychalecky JC, Bryer-Ash M, Rich SS, Bowden DW, Sale MM. Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study. Diabetes. 56: 2135-41. PMID 17513703 DOI: 10.2337/Db06-1017  0.411
2007 Wagenknecht LE, Langefeld CD, Freedman BI, Carr JJ, Bowden DW. A comparison of risk factors for calcified atherosclerotic plaque in the coronary, carotid, and abdominal aortic arteries: The diabetes heart study American Journal of Epidemiology. 166: 340-347. PMID 17493948 DOI: 10.1093/Aje/Kwm091  0.331
2007 Yeboah J, Sane DC, Crouse JR, Herrington DM, Bowden DW. Low plasma levels of FGF-2 and PDGF-BB are associated with cardiovascular events in type II diabetes mellitus (diabetes heart study). Disease Markers. 23: 173-8. PMID 17473387 DOI: 10.1155/2007/962892  0.4
2007 Hanley AJ, Bowden D, Wagenknecht LE, Balasubramanyam A, Langfeld C, Saad MF, Rotter JI, Guo X, Chen YD, Bryer-Ash M, Norris JM, Haffner SM. Associations of adiponectin with body fat distribution and insulin sensitivity in nondiabetic Hispanics and African-Americans. The Journal of Clinical Endocrinology and Metabolism. 92: 2665-71. PMID 17426091 DOI: 10.1210/Jc.2006-2614  0.394
2007 Lakoski SG, Li L, Langefeld CD, Liu Y, Howard TD, Brosnihan KB, Xu J, Bowden DW, Herrington DM. The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study. Experimental and Molecular Pathology. 82: 280-3. PMID 17382928 DOI: 10.1016/J.Yexmp.2007.02.002  0.366
2007 Iyengar SK, Abboud HE, Goddard KA, Saad MF, Adler SG, Arar NH, Bowden DW, Duggirala R, Elston RC, Hanson RL, Ipp E, Kao WH, Kimmel PL, Klag MJ, Knowler WC, et al. Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes. 56: 1577-85. PMID 17363742 DOI: 10.2337/Db06-1154  0.464
2007 Gallagher CJ, Keene KL, Mychaleckyj JC, Langefeld CD, Hirschhorn JN, Henderson BE, Gordon CJ, Freedman BI, Rich SS, Bowden DW, Sale MM. Investigation of the estrogen receptor-alpha gene with type 2 diabetes and/or nephropathy in African-American and European-American populations. Diabetes. 56: 675-84. PMID 17327435 DOI: 10.2337/Db06-0303  0.801
2007 Freedman BI, Hicks PJ, Sale MM, Pierson ED, Langefeld CD, Rich SS, Xu J, McDonough C, Janssen B, Yard BA, van der Woude FJ, Bowden DW. A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 22: 1131-5. PMID 17205963 DOI: 10.1093/Ndt/Gfl717  0.713
2007 Lehtinen AB, Burdon KP, Lewis JP, Langefeld CD, Ziegler JT, Rich SS, Register TC, Carr JJ, Freedman BI, Bowden DW. Association of alpha2-Heremans-Schmid glycoprotein polymorphisms with subclinical atherosclerosis. The Journal of Clinical Endocrinology and Metabolism. 92: 345-52. PMID 17062776 DOI: 10.1210/Jc.2006-0429  0.448
2006 Lange LA, Burdon K, Langefeld CD, Liu Y, Beck SR, Rich SS, Freedman BI, Brosnihan KB, Herrington DM, Wagenknecht LE, Bowden DW. Heritability and expression of C-reactive protein in type 2 diabetes in the Diabetes Heart Study. Annals of Human Genetics. 70: 717-25. PMID 17044846 DOI: 10.1111/J.1469-1809.2006.00280.X  0.513
2006 Elbein SC, Wang X, Karim MA, Freedman BI, Bowden DW, Shuldiner AR, Brancati FL, Kao WH. Role of a proline insertion in the insulin promoter factor 1 (IPF1) gene in African Americans with type 2 diabetes. Diabetes. 55: 2909-14. PMID 17003361 DOI: 10.2337/Db06-0434  0.501
2006 Liu Y, Herrington D, Burdon KP, Langefeld CD, Rich SS, Bowden DW, Freedman BI, Wagenknecht LE. A functional polymorphism in the lymphotoxin-α gene is associated with carotid artery wall thickness: The Diabetes Heart Study European Journal of Cardiovascular Prevention and Rehabilitation. 13: 655-657. PMID 16874159 DOI: 10.1097/01.Hjr.0000214610.83866.2E  0.445
2006 Segade F, Daly KA, Allred D, Hicks PJ, Cox M, Brown M, Hardisty-Hughes RE, Brown SD, Rich SS, Bowden DW. Association of the FBXO11 gene with chronic otitis media with effusion and recurrent otitis media: the Minnesota COME/ROM Family Study. Archives of Otolaryngology--Head & Neck Surgery. 132: 729-33. PMID 16847180 DOI: 10.1001/Archotol.132.7.729  0.367
2006 Bowden DW, Rudock M, Ziegler J, Lehtinen AB, Xu J, Wagenknecht LE, Herrington D, Rich SS, Freedman BI, Carr JJ, Langefeld CD. Coincident linkage of type 2 diabetes, metabolic syndrome, and measures of cardiovascular disease in a genome scan of the diabetes heart study. Diabetes. 55: 1985-94. PMID 16804067 DOI: 10.2337/Db06-0003  0.452
2006 Freedman BI, Bowden DW, Sale MM, Langefeld CD, Rich SS. Genetic susceptibility contributes to renal and cardiovascular complications of type 2 diabetes mellitus Hypertension. 48: 8-13. PMID 16735643 DOI: 10.1161/01.Hyp.0000227047.26988.3E  0.52
2006 Guo X, Saad MF, Langefeld CD, Williams AH, Cui J, Taylor KD, Norris JM, Jinagouda S, Darwin CH, Mitchell BD, Bergman RN, Sutton B, Chen YD, Wagenknecht LE, Bowden DW, et al. Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study. Diabetes. 55: 1723-30. PMID 16731835 DOI: 10.2337/Db05-0428  0.789
2006 Register TC, Lenchik L, Hsu FC, Lohman KK, Freedman BI, Bowden DW, Carr JJ. Type 2 diabetes is not independently associated with spinal trabecular volumetric bone mineral density measured by QCT in the Diabetes Heart Study Bone. 39: 628-633. PMID 16690365 DOI: 10.1016/J.Bone.2006.03.003  0.409
2006 Palmer ND, Langefeld CD, Campbell JK, Williams AH, Saad M, Norris JM, Haffner SM, Rotter JI, Wagenknecht LE, Bergman RN, Rich SS, Bowden DW. Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 55: 911-8. PMID 16567510 DOI: 10.2337/Diabetes.55.04.06.Db05-0813  0.449
2006 Sutton BS, Langefeld CD, Campbell JK, Haffner SM, Norris JM, Scherzinger AL, Wagenknecht LE, Bowden DW. Genetic mapping of a 17q chromosomal region linked to obesity phenotypes in the IRAS family study. International Journal of Obesity (2005). 30: 1433-41. PMID 16520807 DOI: 10.1038/Sj.Ijo.0803298  0.755
2006 Burdon KP, Bento JL, Langefeld CD, Campbell JK, Carr JJ, Wagenknecht LM, Herrington DM, Freedman BI, Rich SS, Bowden DW. Association of protein tyrosine phosphatase-N1 polymorphisms with coronary calcified plaque in the diabetes heart study Diabetes. 55: 651-658. PMID 16505227 DOI: 10.2337/Diabetes.55.03.06.Db05-0058  0.571
2006 Burdon KP, Langefeld CD, Beck SR, Wagenknecht LE, Carr JJ, Rich SS, Freedman BI, Herrington D, Bowden DW. Variants of the CD40 gene but not of the CD40L gene are associated with coronary artery calcification in the Diabetes Heart Study (DHS) American Heart Journal. 151: 706-711. PMID 16504636 DOI: 10.1016/J.Ahj.2005.05.004  0.42
2006 Burdon KP, Langefeld CD, Wagenknecht LE, Carr JJ, Freedman BI, Herrington D, Bowden DW. Association analysis of genes in the renin-angiotensin system with subclinical cardiovascular disease in families with Type 2 diabetes mellitus: The Diabetes Heart Study Diabetic Medicine. 23: 228-234. PMID 16492203 DOI: 10.1111/J.1464-5491.2005.01777.X  0.468
2006 Gallagher CJ, Gordon CJ, Langefeld CD, Mychaleckyj JC, Freedman BI, Rich SS, Bowden DW, Sale MM. Association of the mu-opioid receptor gene with type 2 diabetes mellitus in an African American population. Molecular Genetics and Metabolism. 87: 54-60. PMID 16140553 DOI: 10.1016/J.Ymgme.2005.07.013  0.573
2006 Rich S, Burdon K, Langefeld C, Liu Y, Freedman B, Carr J, Hedrick C, Bowden D. We-W45:5 Human lipoxygenase gene variation in subclinical atherosclerosis: The diabetes heart study Atherosclerosis Supplements. 7: 335. DOI: 10.1016/S1567-5688(06)81334-6  0.386
2006 Bowden D, Lehtinen A, Ziegler J, Herrington D, Wagenknecht L, Rich S, Freedman B, Carr J, Langefeld C. Mo-P2:196 A genome scan for subclinical cardiovascular disease in the diabetes heart study Atherosclerosis Supplements. 7: 89. DOI: 10.1016/S1567-5688(06)80331-4  0.411
2006 Freedman B, Hsu F, Lohman K, Bowden D, Leonchik L, Langefeld C, Xu J, Register T, Rich S, Wagenknecht L. Mo-W2:6 The relationship between calcified atherosclerotic plaque and bone mineral density: The diabetes heart study Atherosclerosis Supplements. 7: 14. DOI: 10.1016/S1567-5688(06)80035-8  0.31
2005 Bento JL, Bowden DW, Mychaleckyj JC, Hirakawa S, Rich SS, Freedman BI, Segade F. Genetic analysis of the GLUT10 glucose transporter (SLC2A10) polymorphisms in Caucasian American type 2 diabetes. Bmc Medical Genetics. 6: 42. PMID 16336637 DOI: 10.1186/1471-2350-6-42  0.451
2005 Bowden DW, Lange LA, Langefeld CD, Brosnihan KB, Freedman BI, Carr JJ, Wagenknecht LE, Herrington DM. The relationship between C-reactive protein and subclinical cardiovascular disease in the Diabetes Heart Study (DHS). American Heart Journal. 150: 1032-8. PMID 16290992 DOI: 10.1016/J.Ahj.2005.01.017  0.328
2005 Freedman BI, Hsu FC, Langefeld CD, Rich SS, Herrington DM, Carr JJ, Xu J, Bowden DW, Wagenknecht LE. The impact of ethnicity and sex on subclinical cardiovascular disease: The Diabetes Heart Study Diabetologia. 48: 2511-2518. PMID 16261310 DOI: 10.1007/S00125-005-0017-2  0.35
2005 Sutton BS, Langefeld CD, Williams AH, Norris JM, Saad MF, Haffner SM, Bowden DW. Association of proopiomelanocortin gene polymorphisms with obesity in the IRAS family study. Obesity Research. 13: 1491-8. PMID 16222047 DOI: 10.1038/Oby.2005.180  0.786
2005 Hsu FC, Zaccaro DJ, Lange LA, Arnett DK, Langefeld CD, Wagenknecht LE, Herrington DM, Beck SR, Freedman BI, Bowden DW, Rich SS. The impact of pedigree structure on heritability estimates for pulse pressure in three studies. Human Heredity. 60: 63-72. PMID 16155398 DOI: 10.1159/000087971  0.306
2005 Burdon KP, Langefeld CD, Beck SR, Wagenknecht LE, Carr JJ, Freedman BI, Herrington D, Bowden DW. Association of genes of lipid metabolism with measures of subclinical cardiovascular disease in the Diabetes Heart Study Journal of Medical Genetics. 42: 720-724. PMID 16141008 DOI: 10.1136/Jmg.2004.029850  0.478
2005 Sale MM, Freedman BI, Hicks PJ, Williams AH, Langefeld CD, Gallagher CJ, Bowden DW, Rich SS. Loci contributing to adult height and body mass index in African American families ascertained for type 2 diabetes. Annals of Human Genetics. 69: 517-27. PMID 16138910 DOI: 10.1046/J.1529-8817.2005.00176.X  0.443
2005 Segade F, Allred DC, Bowden DW. Functional characterization of the promoter of the human glucose transporter 10 gene Biochimica Et Biophysica Acta - Gene Structure and Expression. 1730: 147-158. PMID 16051383 DOI: 10.1016/J.Bbaexp.2005.06.012  0.306
2005 Liu Y, Burdon KP, Langefeld CD, Beck SR, Wagenknecht LE, Rich SS, Bowden DW, Freedman BI. P-selectin gene haplotype associations with albuminuria in the Diabetes Heart Study Kidney International. 68: 741-746. PMID 16014051 DOI: 10.1111/J.1523-1755.2005.00452.X  0.521
2005 Dusel JA, Burdon KP, Hicks PJ, Hawkins GA, Bowden DW, Freedman BI. Identification of podocin (NPHS2) gene mutations in African Americans with nondiabetic end-stage renal disease. Kidney International. 68: 256-62. PMID 15954915 DOI: 10.1111/J.1523-1755.2005.00400.X  0.377
2005 Freedman BI, Langefeld CD, Lohman KK, Bowden DW, Carr JJ, Rich SS, Wagenknecht LE. Relationship between albuminuria and cardiovascular disease in type 2 diabetes Journal of the American Society of Nephrology. 16: 2156-2161. PMID 15872076 DOI: 10.1681/Asn.2004100884  0.337
2005 Sutton BS, Weinert S, Langefeld CD, Williams AH, Campbell JK, Saad MF, Haffner SM, Norris JM, Bowden DW. Genetic analysis of adiponectin and obesity in Hispanic families: the IRAS Family Study. Human Genetics. 117: 107-18. PMID 15843989 DOI: 10.1007/S00439-005-1260-9  0.786
2005 Hsu FC, Lenchik L, Nicklas BJ, Lohman K, Register TC, Mychaleckyj J, Langefeld CD, Freedman BI, Bowden DW, Carr JJ. Heritability of body composition measured by DXA in the Diabetes Heart Study Obesity Research. 13: 312-319. PMID 15800289 DOI: 10.1038/Oby.2005.42  0.35
2005 Bagwell AM, Bento JL, Hychaleckyj JC, Freedman BI, Langefeld CD, Bowden DW. Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes Diabetes. 54: 1185-1190. PMID 15793260 DOI: 10.2337/Diabetes.54.4.1185  0.535
2005 Liu Y, Burdon KP, Langefeld CD, Beck SR, Wagenknecht LE, Rich SS, Bowden DW, Freedman BI. T-786C polymorphism of the endothelial nitric oxide synthase gene is associated with albuminuria in the diabetes heart study Journal of the American Society of Nephrology. 16: 1085-1090. PMID 15743995 DOI: 10.1681/Asn.2004100817  0.513
2005 Hiratani H, Bowden DW, Ikegami S, Shirasawa S, Shimizu A, Iwatani Y, Akamizu T. Multiple SNPs in intron 7 of thyrotropin receptor are associated with Graves' disease Journal of Clinical Endocrinology and Metabolism. 90: 2898-2903. PMID 15741259 DOI: 10.1210/Jc.2004-2148  0.508
2005 Freedman BI, Bowden DW, Rich SS, Valis CJ, Sale MM, Hicks PJ, Langefeld CD. A genome scan for all-cause end-stage renal disease in African Americans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 20: 712-8. PMID 15701670 DOI: 10.1093/Ndt/Gfh704  0.348
2005 Lange LA, Norris JM, Langefeld CD, Nicklas BJ, Wagenknecht LE, Saad MF, Bowden DW. Association of adipose tissue deposition and beta-2 adrenergic receptor variants: The IRAS family study International Journal of Obesity. 29: 449-457. PMID 15672110 DOI: 10.1038/Sj.Ijo.0802883  0.387
2005 Wheeler GL, Shi R, Beck SR, Langefeld CD, Lenchik L, Wagenknecht LE, Freedman BI, Rich SS, Bowden DW, Chen MY, Carr JJ. Pericardial and visceral adipose tissues measured volumetrically with computed tomography are highly associated in type 2 diabetic families. Investigative Radiology. 40: 97-101. PMID 15654254 DOI: 10.1097/00004424-200502000-00007  0.344
2005 Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Hedrick CC, Wagenknecht LE, Bergman RN. A genome scan for fasting insulin and fasting glucose identifies a quantitative trait locus on chromosome 17p: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes. 54: 290-5. PMID 15616041 DOI: 10.2337/Diabetes.54.1.290  0.349
2005 Norris JM, Langefeld CD, Scherzinger AL, Rich SS, Bookman E, Beck SR, Saad MF, Haffner SM, Bergman RN, Bowden DW, Wagenknecht LE. Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study. International Journal of Obesity (2005). 29: 67-77. PMID 15534617 DOI: 10.1038/Sj.Ijo.0802793  0.312
2004 Karim MA, Wang X, Zhang Z, Bowden DW, Freedman BI, Elbein SC. Association of an insulin gene promoter insertion polymorphism with type 2 diabetes and diabetic nephropathy in African Americans. Molecular Genetics and Metabolism. 83: 344-6. PMID 15589123 DOI: 10.1016/J.Ymgme.2004.08.003  0.519
2004 Lenchik L, Hsu FC, Register TC, Lohman KK, Freedman BI, Langefeld CD, Bowden DW, Carr JJ. Heritability of spinal trabecular volumetric bone mineral density measured by QCT in the diabetes heart study Calcified Tissue International. 75: 305-312. PMID 15549645 DOI: 10.1007/S00223-004-0249-Z  0.348
2004 Daly KA, Brown WM, Segade F, Bowden DW, Keats BJ, Lindgren BR, Levine SC, Rich SS. Chronic and recurrent otitis media: a genome scan for susceptibility loci. American Journal of Human Genetics. 75: 988-97. PMID 15514890 DOI: 10.1086/426061  0.342
2004 Palmer ND, Bento JL, Mychaleckyj JC, Langefeld CD, Campbell JK, Norris JM, Haffner SM, Bergman RN, Bowden DW. Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes. 53: 3013-9. PMID 15504985 DOI: 10.2337/Diabetes.53.11.3013  0.508
2004 Bento JL, Palmer ND, Mychaleckyj JC, Lange LA, Langefeld CD, Rich SS, Freedman BI, Bowden DW. Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes. Diabetes. 53: 3007-12. PMID 15504984 DOI: 10.2337/Diabetes.53.11.3007  0.586
2004 Register TC, Burdon KP, Lenchik L, Bowden DW, Hawkins GA, Nicklas BJ, Lohman K, Hsu FC, Langefeld CD, Carr JJ. Variability of serum soluble intercellular adhesion molecule-1 measurements attributable to a common polymorphism Clinical Chemistry. 50: 2185-2187. PMID 15502096 DOI: 10.1373/Clinchem.2004.036806  0.407
2004 Freedman BI, Langefeld CD, Rich SS, Valis CJ, Sale MM, Williams AH, Brown WM, Beck SR, Hicks PJ, Bowden DW. A genome scan for ESRD in black families enriched for nondiabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 15: 2719-27. PMID 15466277 DOI: 10.1097/01.Asn.0000141312.39483.4F  0.359
2004 Bowden DW, Colicigno CJ, Langefeld CD, Sale MM, Williams A, Anderson PJ, Rich SS, Freedman BI. A genome scan for diabetic nephropathy in African Americans Kidney International. 66: 1517-1526. PMID 15458446 DOI: 10.1111/J.1523-1755.2004.00915.X  0.501
2004 Bensen JT, Hsu FC, Brown WM, Sutton BS, Norris JM, Tracy RP, Jenny NS, Saad MF, Haffner S, Bowden DW, Langefeld CD. Association analysis of the plasminogen activator inhibitor-1 4G/5G polymorphism in Hispanics and African Americans: the IRAS family study. Human Heredity. 57: 128-37. PMID 15297806 DOI: 10.1159/000079243  0.754
2004 Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Wagenknecht LE, Bergman RN. Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes. 53: 1866-75. PMID 15220212 DOI: 10.2337/Diabetes.53.7.1866  0.403
2004 Langefeld CD, Beck SR, Bowden DW, Rich SS, Wagenknecht LE, Freedman BI. Heritability of GFR and Albuminuria in Caucasians with Type 2 Diabetes Mellitus American Journal of Kidney Diseases. 43: 796-800. PMID 15112169 DOI: 10.1053/J.Ajkd.2003.12.043  0.391
2004 Langefeld CD, Wagenknecht LE, Rotter JI, Williams AH, Hokanson JE, Saad MF, Bowden DW, Haffner S, Norris JM, Rich SS, Mitchell BD. Linkage of the metabolic syndrome to 1q23-q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study. Diabetes. 53: 1170-4. PMID 15047638 DOI: 10.2337/Diabetes.53.4.1170  0.336
2004 Sale MM, Freedman BI, Langefeld CD, Williams AH, Hicks PJ, Colicigno CJ, Beck SR, Brown WM, Rich SS, Bowden DW. A genome-wide scan for type 2 diabetes in African-American families reveals evidence for a locus on chromosome 6q. Diabetes. 53: 830-7. PMID 14988270 DOI: 10.2337/Diabetes.53.3.830  0.494
2004 Bagwell AM, Bailly A, Mychaleckyj JC, Freedman BI, Bowden DW. Comparative genomic analysis of the HNF-4α transcription factor gene Molecular Genetics and Metabolism. 81: 112-121. PMID 14741192 DOI: 10.1016/J.Ymgme.2003.10.011  0.356
2003 Bowden DW. Genetics of kidney disease Kidney International, Supplement. 63. PMID 12864867 DOI: 10.1046/J.1523-1755.63.S83.3.X  0.402
2003 Bensen JT, Langefeld CD, Hawkins GA, Green LE, Mychaleckyj JC, Brewer CS, Kiger DS, Binford SM, Colicigno CJ, Allred DC, Freedman BI, Bowden DW. Nucleotide variation, haplotype structure, and association with end-stage renal disease of the human interleukin-1 gene cluster. Genomics. 82: 194-217. PMID 12837270 DOI: 10.1016/S0888-7543(03)00123-X  0.525
2003 Akamizu T, Hiratani H, Ikegami S, Rich SS, Bowden DW. Association study of autoimmune thyroid disease at 5q23-q33 in Japanese patients Journal of Human Genetics. 48: 236-242. PMID 12768441 DOI: 10.1007/S10038-003-0017-3  0.369
2003 Henkin L, Bergman RN, Bowden DW, Ellsworth DL, Haffner SM, Langefeld CD, Mitchell BD, Norris JM, Rewers M, Saad MF, Stamm E, Wagenknecht LE, Rich SS. Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methods. Annals of Epidemiology. 13: 211-7. PMID 12684185 DOI: 10.1016/S1047-2797(02)00412-X  0.36
2003 Bensen JT, Langefeld CD, Li L, McCall CE, Cousart SL, Dryman BN, Freedman BI, Bowden DW. Association of an IL-1A 3'UTR polymorphism with end-stage renal disease and IL-1 alpha expression. Kidney International. 63: 1211-9. PMID 12631337 DOI: 10.1046/J.1523-1755.2003.00856.X  0.387
2002 Bowden DW. Genetics of diabetes complications Curr Diab Rep. 2: 191-200. PMID 12643139 DOI: 10.1007/S11892-002-0080-8  0.458
2002 Sale MM, FitzGerald LM, Charlesworth JC, Bowden DW, Rich SS. Evidence for a novel type 1 diabetes susceptibility locus on chromosome 8. Diabetes. 51: S316-9. PMID 12475769 DOI: 10.2337/Diabetes.51.2007.S316  0.498
2002 Satko SG, Langefeld CD, Daeihagh P, Bowden DW, Rich SS, Freedman BI. Nephropathy in siblings of African Americans with overt type 2 diabetic nephropathy American Journal of Kidney Diseases. 40: 489-494. PMID 12200799 DOI: 10.1053/Ajkd.2002.34888  0.436
2002 Freedman BI, Rich SS, Yu H, Roh BH, Bowden DW. Linkage heterogeneity of end-stage renal disease on human chromosome 10 Kidney International. 62: 770-774. PMID 12164858 DOI: 10.1046/J.1523-1755.2002.00534.X  0.475
2002 Lange LA, Bowden DW, Langefeld CD, Wagenknecht LE, Carr JJ, Rich SS, Riley WA, Freedman BI. Heritability of carotid artery intima-medial thickness in type 2 diabetes. Stroke; a Journal of Cerebral Circulation. 33: 1876-81. PMID 12105369 DOI: 10.1161/01.Str.0000019909.71547.Aa  0.392
2002 Gitter J, Langefeld CD, Rich SS, Pedley CF, Bowden DW, Freedman BI. Prevalence of nephropathy in black patients with type 2 diabetes mellitus American Journal of Nephrology. 22: 35-41. PMID 11919401 DOI: 10.1159/000046672  0.402
2002 Yu H, Song Q, Freedman BI, Chao J, Chao L, Rich SS, Bowden DW. Association of the tissue kallikrein gene promoter with ESRD and hypertension. Kidney International. 61: 1030-9. PMID 11849458 DOI: 10.1046/J.1523-1755.2002.00198.X  0.466
2001 Fossey SC, Mychaleckyj JC, Pendleton JK, Snyder JR, Bensen JT, Hirakawa S, Rich SS, Freedman BI, Bowden DW. A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20 Genomics. 76: 45-57. PMID 11549316 DOI: 10.1006/Geno.2001.6584  0.37
2001 Wagenknecht LE, Bowden DW, Carr JJ, Langefeld CD, Freedman BI, Rich SS. Familial aggregation of coronary artery calcium in families with type 2 diabetes Diabetes. 50: 861-866. PMID 11289053 DOI: 10.2337/Diabetes.50.4.861  0.46
2001 Akamizu T, Sale MM, Rich SS, Hiratani H, Noh JY, Kanamoto N, Saijo M, Miyamoto Y, Saito Y, Nakao K, Bowden DW. Association of autoimmune thyroid disease with microsatellite markers for the thyrotropin receptor gene and CTLA-4 in Japanese patients. Thyroid : Official Journal of the American Thyroid Association. 10: 851-8. PMID 11081251 DOI: 10.1089/Thy.2000.10.851  0.441
2000 Freedman BI, Yu H, Anderson PJ, Roh BH, Rich SS, Bowden DW. Genetic analysis of nitric oxide and endothelin in end-stage renal disease Nephrology Dialysis Transplantation. 15: 1794-1800. PMID 11071967 DOI: 10.1093/Ndt/15.11.1794  0.539
2000 Yu H, Anderson PJ, Freedman BI, Rich SS, Bowden DW. Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease Genomics. 69: 225-234. PMID 11031105 DOI: 10.1006/Geno.2000.6330  0.474
2000 Fossey SC, Kuroda S, Price JA, Pendleton JK, Freedman BI, Bowden DW. Identification and characterization of PRKCBP1, a candidate RACK-like protein Mammalian Genome. 11: 919-925. PMID 11003709 DOI: 10.1007/S003350010174  0.422
2000 Price JA, Fossey SC, Sale MM, Brewer CS, Freedman BI, Wuerth JP, Bowden DW. Analysis of the HNF4α gene in Caucasian Type II diabetic nephropathic patients Diabetologia. 43: 364-372. PMID 10768098 DOI: 10.1007/S001250050055  0.441
2000 Yu H, Freedman BI, Rich SS, Bowden DW. Human Na+/H+ exchanger genes: Identification of polymorphisms by radiation hybrid mapping and analysis of linkage in end-stage renal disease Hypertension. 35: 135-143. PMID 10642288 DOI: 10.1161/01.Hyp.35.1.135  0.434
1999 Price JA, Brewer CS, Howard TD, Fossey SC, Sale MM, Ji L, Krolewski AS, Bowden DW. A physical map of the 20q12-q13.1 region associated with type 2 diabetes Genomics. 62: 208-215. PMID 10610714 DOI: 10.1006/Geno.1999.6007  0.428
1999 Gonzalez E, Bamshad M, Sato N, Mummidi S, Dhanda R, Catano G, Cabrera S, McBride M, Cao XH, Merrill G, O'Connell P, Bowden DW, Freedman BI, Anderson SA, Walter EA, et al. Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes. Proceedings of the National Academy of Sciences of the United States of America. 96: 12004-9. PMID 10518566 DOI: 10.1073/Pnas.96.21.12004  0.345
1999 Yu H, Sale M, Rich SS, Spray BJ, Roh BH, Bowden DW, Freedman BI. Evaluation of markers on human chromosome 10, including the homologue of the rodent Rf-1 gene, for linkage to ESRD in black patients American Journal of Kidney Diseases. 33: 294-300. PMID 10023641 DOI: 10.1016/S0272-6386(99)70303-3  0.406
1998 Price JA, Wright JT, Kula K, Bowden DW, Hart TC. A common DLX3 gene mutation is responsible for tricho-dento-osseous syndrome in Virginia and North Carolina families Journal of Medical Genetics. 35: 825-828. PMID 9783705 DOI: 10.1136/Jmg.35.10.825  0.331
1998 Price JA, Bowden DW, Hart TC. Identification of a CA/TG repeat polymorphism proximal to the human DLX3 gene Human Heredity. 48: 288-290. PMID 9748700 DOI: 10.1159/000022818  0.317
1998 Hart TC, Bowden DW, Ghaffar KA, Wang W, Cutler CW, Cebeci I, Efeoglu A, Firatli E. Sublocalization of the Papillon-Lefevre syndrome locus on 11q14-q21 American Journal of Medical Genetics. 79: 134-139. PMID 9741471 DOI: 10.1002/(Sici)1096-8628(19980901)79:2<134::Aid-Ajmg9>3.0.Co;2-Q  0.33
1998 Yu H, Bowden DW, Spray BJ, Rich SS, Freedman BI. Identification of human plasma kallikrein gene polymorphisms and evaluation of their role in end-stage renal disease Hypertension. 31: 906-911. PMID 9535413 DOI: 10.1161/01.Hyp.31.4.906  0.508
1998 Hart TC, Pallos D, Bowden DW, Bolyard J, Pettenati MJ, Cortelli JR. Genetic linkage of hereditary gingival fibromatosis to chromosome 2p21 American Journal of Human Genetics. 62: 876-883. PMID 9529355 DOI: 10.1086/301797  0.341
1998 Freedman BI, Bowden DW, Rich SS, Appel RG. Genetic initiation of hypertensive and diabetic nephropathy American Journal of Hypertension. 11: 251-257. PMID 9524057 DOI: 10.1016/S0895-7061(97)00481-0  0.383
1997 Hart TC, Bowden DW, Bolyard J, Kula K, Hall K, Wright JT. Genetic linkage of the tricho-dento-osseous syndrome to chromosome 17q21 Human Molecular Genetics. 6: 2279-2284. PMID 9361034 DOI: 10.1093/Hmg/6.13.2279  0.329
1997 Bowden DW, Sale M, Howard TD, Qadri A, Spray BJ, Rothschild CB, Akots G, Rich SS, Freedman BI. Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy Diabetes. 46: 882-886. PMID 9133559 DOI: 10.2337/Diab.46.5.882  0.448
1997 Freedman BI, Yu H, Spray BJ, Rich SS, Rothschild CB, Bowden DW. Genetic linkage analysis of growth factor loci and end-stage renal disease in African Americans Kidney International. 51: 819-825. PMID 9067916 DOI: 10.1038/Ki.1997.115  0.457
1997 Rich SS, Freedman BI, Bowden DW. Genetic epidemiology of diabetic complications Diabetes Reviews. 5: 165-173.  0.337
1996 Yu H, Bowden DW, Spray BJ, Rich SS, Freedman BI. Linkage Analysis between Loci in the Renin-Angiotensin Axis and End-Stage Renal Disease in African Americans Journal of the American Society of Nephrology. 7: 2559-2564. PMID 8989734  0.306
1996 Fajans SS, Bell GI, Bowden DW, Halter JB, Polonsky KS. Maturity onset diabetes of the young (MODY) Diabetic Medicine. 13. PMID 8894490  0.313
1996 Howard TD, Akots G, Bowden DW. Physical and genetic mapping of the muscle phosphofructokinase gene (PFKM): Reassignment to human chromosome 12q Genomics. 34: 122-127. PMID 8661033 DOI: 10.1006/Geno.1996.0250  0.384
1995 Rothschild CB, Freedman BI, Hodge R, Rao PN, Pettenati MJ, Anderson RA, Akots G, Qadri A, Roh B, Fajans SS, Reis A, Morris DJ, Usala A, Hayward C, Brock D, ... ... Bowden DW, et al. Fructose-1,6-Bisphosphatase: Genetic and Physical Mapping to Human Chromosome 9q22.3 and Evaluation in Non-Insulin-Dependent Diabetes Mellitus Genomics. 29: 187-194. PMID 8530070 DOI: 10.1006/Geno.1995.1230  0.44
1995 Bowden DW, Krawchuk MD, Weaver EJ, Howard TD, Knowlton RG, Rao PN, Pettenati MJ, Hayworth R, Wagner BJ, Rothschild CB. D20S16 is a complex interspersed repeated sequence: genetic and physical analysis of the locus Genomics. 25: 394-403. PMID 7789973 DOI: 10.1016/0888-7543(95)80039-O  0.354
1995 Freedman BI, Bowden DW. The role of genetic factors in the development of end-stage renal disease Current Opinion in Nephrology and Hypertension. 4: 230-234. PMID 7648217 DOI: 10.1097/00041552-199505000-00005  0.394
1994 Howard TD, Rothschild CB, Bowden DW. D20S213, a microsatellite polymorphism near the D20S16 locus Human Molecular Genetics. 3: 677. PMID 8069320 DOI: 10.1093/Hmg/3.4.677-A  0.411
1994 Schuster MK, Bowden DW. D10S681, a microsatellite polymorphism near the RET locus Human Molecular Genetics. 3: 677. PMID 8069319 DOI: 10.1093/Hmg/3.4.677  0.426
1994 Fajans SS, Bell GI, Bowden DW, Halter JB, Polonsky KS. Maturity-onset diabetes of the young Life Sciences. 55: 413-422. PMID 8035658 DOI: 10.1016/0024-3205(94)90052-3  0.319
1994 Wiechmann AF, Haro KC, Bowden DW. Three microsatellite polymorphisms at the recoverin locus on chromosome 17 Human Molecular Genetics. 3: 1028. PMID 7951220 DOI: 10.1093/Hmg/3.6.1028  0.358
1992 Rothschild CB, Akots G, Fajans SS, Bowden DW. A microsatellite polymorphism associated with the PLC1 (phospholipase C) locus: Identification, mapping, and linkage to the MODY locus on chromosome 20 Genomics. 13: 560-564. PMID 1639386 DOI: 10.1016/0888-7543(92)90125-C  0.385
1992 Bowden DW, Gravius TC, Akots G, Fajans SS. Identification of genetic markers flanking the locus for maturity-onset diabetes of the young on human chromosome 20 Diabetes. 41: 88-92. PMID 1345781 DOI: 10.2337/Diab.41.1.88  0.429
1991 Bowden DW, Akots G, Rothschild CB. An insertion deletion polymorphism associated with C-FES Nucleic Acids Research. 19: 4311. PMID 1870997 DOI: 10.1093/Nar/19.15.4311  0.349
1990 Bowden DW, Gravius TC. CRI-J177 (DYS152): A polymorphic Y chromosome locus Nucleic Acids Research. 18: 5582. PMID 1977127 DOI: 10.1093/Nar/18.18.5582  0.34
1987 Donis-Keller H, Green P, Helms C, Cartinhour S, Weiffenbach B, Stephens K, Keith TP, Bowden DW, Smith DR, Lander ES. A genetic linkage map of the human genome. Cell. 51: 319-37. PMID 3664638 DOI: 10.1016/0092-8674(87)90158-9  0.338
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