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Isaac S. Chan, Ph.D. - Publications

Affiliations: 
2012 Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Genetics, Molecular Biology, Oncology
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Pereira TA, Syn WK, MacHado MV, Vidigal PV, Resende V, Voieta I, Xie G, Otoni A, Souza MM, Santos ET, Chan IS, Trindade GV, Choi SS, Witek RP, Pereira FE, et al. Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni. Clinical Science (London, England : 1979). PMID 26201095 DOI: 10.1042/Cs20150117  0.523
2014 Chan IS, Guy CD, Machado MV, Wank A, Kadiyala V, Michelotti G, Choi S, Swiderska-Syn M, Karaca G, Pereira TA, Yip-Schneider MT, Max Schmidt C, Diehl AM. Alcohol activates the hedgehog pathway and induces related procarcinogenic processes in the alcohol-preferring rat model of hepatocarcinogenesis. Alcoholism, Clinical and Experimental Research. 38: 787-800. PMID 24164383 DOI: 10.1111/Acer.12279  0.487
2013 Pereira TA, Xie G, Choi SS, Syn WK, Voieta I, Lu J, Chan IS, Swiderska M, Amaral KB, Antunes CM, Secor WE, Witek RP, Lambertucci JR, Pereira FL, Diehl AM. Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni. Liver International : Official Journal of the International Association For the Study of the Liver. 33: 149-61. PMID 23121638 DOI: 10.1111/Liv.12016  0.534
2013 Xie G, Choi SS, Syn WK, Michelotti GA, Swiderska M, Karaca G, Chan IS, Chen Y, Diehl AM. Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation. Gut. 62: 299-309. PMID 22362915 DOI: 10.1136/Gutjnl-2011-301494  0.551
2012 Chan IS, Guy CD, Chen Y, Lu J, Swiderska-Syn M, Michelotti GA, Karaca G, Xie G, Krüger L, Syn WK, Anderson BR, Pereira TA, Choi SS, Baldwin AS, Diehl AM. Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma. Cancer Research. 72: 6344-50. PMID 23066040 DOI: 10.1158/0008-5472.Can-12-1068  0.529
2012 Chen Y, Choi SS, Michelotti GA, Chan IS, Swiderska-Syn M, Karaca GF, Xie G, Moylan CA, Garibaldi F, Premont R, Suliman HB, Piantadosi CA, Diehl AM. Hedgehog controls hepatic stellate cell fate by regulating metabolism. Gastroenterology. 143: 1319-29.e1-11. PMID 22885334 DOI: 10.1053/J.Gastro.2012.07.115  0.542
2012 Syn WK, Agboola KM, Swiderska M, Michelotti GA, Liaskou E, Pang H, Xie G, Philips G, Chan IS, Karaca GF, Pereira Tde A, Chen Y, Mi Z, Kuo PC, Choi SS, et al. NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease. Gut. 61: 1323-9. PMID 22427237 DOI: 10.1136/Gutjnl-2011-301857  0.547
2012 Chan IS, Swiderska M, Guy CD, Chen Y, Karaca G, Xie G, Choi SS, Michelotti GA, Diehl AM. Su1587 Hedgehog Inhibition Regulates the Stromal Microenvironment in Hepatocellular Carcinoma via Suppression of the Warburg Effect Gastroenterology. 142: S-972. DOI: 10.1016/S0016-5085(12)63767-6  0.471
2011 Philips GM, Chan IS, Swiderska M, Schroder VT, Guy C, Karaca GF, Moylan C, Venkatraman T, Feuerlein S, Syn WK, Jung Y, Witek RP, Choi S, Michelotti GA, Rangwala F, et al. Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. Plos One. 6: e23943. PMID 21912653 DOI: 10.1371/Journal.Pone.0023943  0.586
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