| Year |
Citation |
Score |
| 2024 |
Doherty CM, Patterson PR, Emeanuwa JA, Belmares Ortega J, Fox BA, Bzik DJ, Denkers EY. T lymphocyte-dependent IL-10 down-regulates a cytokine storm driven by GRA24. Mbio. e0145524. PMID 39440975 DOI: 10.1128/mbio.01455-24 |
0.519 |
|
| 2022 |
Snyder LM, Belmares-Ortega J, Doherty CM, Denkers EY. Impact of MyD88, Microbiota, and Location on Type 1 and Type 3 Innate Lymphoid Cells during Infection. Immunohorizons. 6: 660-670. PMID 36096673 DOI: 10.4049/immunohorizons.2200070 |
0.46 |
|
| 2021 |
Doherty CM, Romero AD, Denkers EY. Impact of IFN-y and CD40 signalling on Toxoplasma gondii cyst formation in differentiated Neuro-2a neuroblastoma cells. Parasite Immunology. 44: e12897. PMID 34762755 DOI: 10.1111/pim.12897 |
0.375 |
|
| 2021 |
Snyder LM, Doherty CM, Mercer HL, Denkers EY. Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade. Plos Pathogens. 17: e1009970. PMID 34597344 DOI: 10.1371/journal.ppat.1009970 |
0.506 |
|
| 2021 |
Menard KL, Bu L, Denkers EY. Transcriptomics analysis of Toxoplasma gondii-infected mouse macrophages reveals coding and noncoding signatures in the presence and absence of MyD88. Bmc Genomics. 22: 130. PMID 33622246 DOI: 10.1186/s12864-021-07437-0 |
0.44 |
|
| 2020 |
Snyder LM, Denkers EY. From Initiators to Effectors: Roadmap Through the Intestine During Encounter of With the Mucosal Immune System. Frontiers in Cellular and Infection Microbiology. 10: 614701. PMID 33505924 DOI: 10.3389/fcimb.2020.614701 |
0.369 |
|
| 2020 |
Mercer HL, Snyder LM, Doherty CM, Fox BA, Bzik DJ, Denkers EY. Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity. Plos Pathogens. 16: e1008572. PMID 32413093 DOI: 10.1371/journal.ppat.1008572 |
0.454 |
|
| 2018 |
Menard KL, Haskins BE, Colombo AP, Denkers EY. Toxoplasma gondii Manipulates Expression of Host Long Noncoding RNA during Intracellular Infection. Scientific Reports. 8: 15017. PMID 30301916 DOI: 10.1038/s41598-018-33274-5 |
0.34 |
|
| 2015 |
Sun S, Lourie R, Cohen SB, Ji Y, Goodrich JK, Poole AC, Ley RE, Denkers EY, McGuckin MA, Long Q, Duhamel GE, Simpson KW, Qi L. Epithelial Sel1L is required for the maintenance of intestinal homeostasis. Molecular Biology of the Cell. PMID 26631554 DOI: 10.1091/Mbc.E15-10-0724 |
0.345 |
|
| 2015 |
Cohen SB, Denkers EY. Impact of Toxoplasma gondii on Dendritic Cell Subset Function in the Intestinal Mucosa. Journal of Immunology (Baltimore, Md. : 1950). 195: 2754-62. PMID 26283477 DOI: 10.4049/Jimmunol.1501137 |
0.479 |
|
| 2015 |
Cohen SB, Denkers EY. The gut mucosal immune response to Toxoplasma gondii Parasite Immunology. 37: 108-117. PMID 25418610 DOI: 10.1111/pim.12164 |
0.355 |
|
| 2015 |
Cohen SB, Smith NL, McDougal C, Pepper M, Shah S, Yap GS, Acha-Orbea H, Jiang A, Clausen BE, Rudd BD, Denkers EY. Beta-catenin signaling drives differentiation and proinflammatory function of IRF8-dependent dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 210-22. PMID 25416805 DOI: 10.4049/Jimmunol.1402453 |
0.377 |
|
| 2014 |
Cohen SB, Denkers EY. Border maneuvers: Deployment of mucosal immune defenses against Toxoplasma gondii Mucosal Immunology. 7: 744-752. PMID 24717355 DOI: 10.1038/Mi.2014.25 |
0.435 |
|
| 2013 |
Cohen SB, Maurer KJ, Egan CE, Oghumu S, Satoskar AR, Denkers EY. CXCR3-Dependent CD4+ T Cells Are Required to Activate Inflammatory Monocytes for Defense against Intestinal Infection Plos Pathogens. 9. PMID 24130498 DOI: 10.1371/Journal.Ppat.1003706 |
0.565 |
|
| 2013 |
Smith NL, Abi Abdallah DS, Butcher BA, Denkers EY, Baird B, Holowka D. Toxoplasma gondii inhibits mast cell degranulation by suppressing phospholipase Cγ-mediated Ca(2+) mobilization. Frontiers in Microbiology. 4: 179. PMID 23847603 DOI: 10.3389/Fmicb.2013.00179 |
0.822 |
|
| 2013 |
Egan CE, Daugherity EK, Rogers AB, Abi Abdallah DS, Denkers EY, Maurer KJ. CCR2 and CD44 Promote Inflammatory Cell Recruitment during Fatty Liver Formation in a Lithogenic Diet Fed Mouse Model Plos One. 8. PMID 23762326 DOI: 10.1371/Journal.Pone.0065247 |
0.779 |
|
| 2013 |
Schneider AG, Abi Abdallah DS, Butcher BA, Denkers EY. Toxoplasma gondii triggers phosphorylation and nuclear translocation of dendritic cell STAT1 while simultaneously blocking IFNγ-induced STAT1 transcriptional activity. Plos One. 8: e60215. PMID 23527309 DOI: 10.1371/Journal.Pone.0060215 |
0.842 |
|
| 2012 |
Abi Abdallah DS, Denkers EY. Neutrophils cast extracellular traps in response to protozoan parasites. Frontiers in Immunology. 3: 382. PMID 23248631 DOI: 10.3389/Fimmu.2012.00382 |
0.813 |
|
| 2012 |
Mahamed DA, Mills JH, Egan CE, Denkers EY, Bynoe MS. CD73-generated adenosine facilitates Toxoplasma gondii differentiation to long-lived tissue cysts in the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 109: 16312-7. PMID 22988118 DOI: 10.1073/Pnas.1205589109 |
0.432 |
|
| 2012 |
McBerry C, Egan CE, Rani R, Yang Y, Wu D, Boespflug N, Boon L, Butcher B, Mirpuri J, Hogan SP, Denkers EY, Aliberti J, Herbert DR. Trefoil factor 2 negatively regulates type 1 immunity against Toxoplasma gondii. Journal of Immunology (Baltimore, Md. : 1950). 189: 3078-84. PMID 22896633 DOI: 10.4049/Jimmunol.1103374 |
0.584 |
|
| 2012 |
Denkers EY, Schneider AG, Cohen SB, Butcher BA. Phagocyte responses to protozoan infection and how Toxoplasma gondii meets the challenge. Plos Pathogens. 8: e1002794. PMID 22876173 DOI: 10.1371/Journal.Ppat.1002794 |
0.596 |
|
| 2012 |
Craven M, Egan CE, Dowd SE, McDonough SP, Dogan B, Denkers EY, Bowman D, Scherl EJ, Simpson KW. Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease. Plos One. 7: e41594. PMID 22848538 DOI: 10.1371/Journal.Pone.0041594 |
0.32 |
|
| 2012 |
Abi Abdallah DS, Lin C, Ball CJ, King MR, Duhamel GE, Denkers EY. Toxoplasma gondii triggers release of human and mouse neutrophil extracellular traps. Infection and Immunity. 80: 768-77. PMID 22104111 DOI: 10.1128/Iai.05730-11 |
0.834 |
|
| 2012 |
Denkers EY, Bzik DJ, Fox BA, Butcher BA. An inside job: hacking into Janus kinase/signal transducer and activator of transcription signaling cascades by the intracellular protozoan Toxoplasma gondii. Infection and Immunity. 80: 476-82. PMID 22104110 DOI: 10.1128/Iai.05974-11 |
0.475 |
|
| 2012 |
Egan CE, Cohen SB, Denkers EY. Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger. Immunology and Cell Biology. 90: 668-75. PMID 22064707 DOI: 10.1038/Icb.2011.93 |
0.494 |
|
| 2012 |
Denkers EY, Butcher BA. Toxoplasma gondii parasites take control within host cells: This parasite puppet master lives mostly without causing disease for its hosts, establishing lifelong asymptomatic infections Microbe. 7. DOI: 10.1128/Microbe.7.360.1 |
0.479 |
|
| 2011 |
Butcher BA, Fox BA, Rommereim LM, Kim SG, Maurer KJ, Yarovinsky F, Herbert DR, Bzik DJ, Denkers EY. Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control. Plos Pathogens. 7: e1002236. PMID 21931552 DOI: 10.1371/Journal.Ppat.1002236 |
0.616 |
|
| 2011 |
Egan CE, Maurer KJ, Cohen SB, Mack M, Simpson KW, Denkers EY. Synergy between intraepithelial lymphocytes and lamina propria T cells drives intestinal inflammation during infection. Mucosal Immunology. 4: 658-70. PMID 21796113 DOI: 10.1038/Mi.2011.31 |
0.49 |
|
| 2011 |
Abi Abdallah DS, Egan CE, Butcher BA, Denkers EY. Mouse neutrophils are professional antigen-presenting cells programmed to instruct Th1 and Th17 T-cell differentiation. International Immunology. 23: 317-26. PMID 21422151 DOI: 10.1093/Intimm/Dxr007 |
0.806 |
|
| 2011 |
Denkers EY. Understanding neutrophil function during Toxoplasma gondii infection Neutrophils in Infectious Diseases. 59-66. DOI: 10.2174/978160805023911101010059 |
0.407 |
|
| 2010 |
Sukhumavasi W, Warren AL, Del Rio L, Denkers EY. Absence of mitogen-activated protein kinase family member c-Jun N-terminal kinase-2 enhances resistance to Toxoplasma gondii. Experimental Parasitology. 126: 415-20. PMID 20117109 DOI: 10.1016/J.Exppara.2010.01.019 |
0.8 |
|
| 2010 |
Denkers EY. Toll-like receptor initiated host defense against Toxoplasma gondii. Journal of Biomedicine & Biotechnology. 2010: 737125. PMID 19911079 DOI: 10.1155/2010/737125 |
0.447 |
|
| 2010 |
Craven M, Egan CE, Dogan B, Dowd SE, Denkers E, McDonough S, Scherl EJ, Simpson KW. 68 CCR2 Deletion Ameloriates Ileal Inflammation, Limits Dysbiosis, and Prevents Invasion by Adherent and Invasive E. coli (AIEC) in Toxoplasma gondii Infected Mice Gastroenterology. 138: S-14. DOI: 10.1016/S0016-5085(10)60063-7 |
0.392 |
|
| 2009 |
Leng J, Butcher BA, Denkers EY. Dysregulation of macrophage signal transduction by Toxoplasma gondii: past progress and recent advances. Parasite Immunology. 31: 717-28. PMID 19891610 DOI: 10.1111/J.1365-3024.2009.01122.X |
0.733 |
|
| 2009 |
Leng J, Denkers EY. Toxoplasma gondii inhibits covalent modification of histone H3 at the IL-10 promoter in infected macrophages. Plos One. 4: e7589. PMID 19859561 DOI: 10.1371/Journal.Pone.0007589 |
0.742 |
|
| 2009 |
Egan CE, Craven MD, Leng J, Mack M, Simpson KW, Denkers EY. CCR2-dependent intraepithelial lymphocytes mediate inflammatory gut pathology during Toxoplasma gondii infection. Mucosal Immunology. 2: 527-35. PMID 19741601 DOI: 10.1038/Mi.2009.105 |
0.755 |
|
| 2009 |
Denkers EY. A gut feeling for microbes: getting it going between a parasite and its host. Cell Host & Microbe. 6: 104-6. PMID 19683676 DOI: 10.1016/J.Chom.2009.07.009 |
0.363 |
|
| 2009 |
Egan CE, Sukhumavasi W, Butcher BA, Denkers EY. Functional aspects of Toll-like receptor/MyD88 signalling during protozoan infection: focus on Toxoplasma gondii. Clinical and Experimental Immunology. 156: 17-24. PMID 19161444 DOI: 10.1111/J.1365-2249.2009.03876.X |
0.807 |
|
| 2009 |
Leng J, Butcher BA, Egan CE, Abi Abdallah DS, Denkers EY. Toxoplasma gondii prevents chromatin remodeling initiated by TLR-triggered macrophage activation. Journal of Immunology (Baltimore, Md. : 1950). 182: 489-97. PMID 19109180 DOI: 10.4049/Jimmunol.182.1.489 |
0.813 |
|
| 2008 |
Bierly AL, Shufesky WJ, Sukhumavasi W, Morelli AE, Denkers EY. Dendritic cells expressing plasmacytoid marker PDCA-1 are Trojan horses during Toxoplasma gondii infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 8485-91. PMID 19050266 DOI: 10.4049/Jimmunol.181.12.8485 |
0.817 |
|
| 2008 |
Sukhumavasi W, Egan CE, Warren AL, Taylor GA, Fox BA, Bzik DJ, Denkers EY. TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite. Journal of Immunology (Baltimore, Md. : 1950). 181: 3464-73. PMID 18714019 DOI: 10.4049/Jimmunol.181.5.3464 |
0.839 |
|
| 2008 |
Denkers EY, Striepen B. Deploying parasite profilin on a mission of invasion and danger. Cell Host & Microbe. 3: 61-3. PMID 18312839 DOI: 10.1016/J.Chom.2008.01.003 |
0.525 |
|
| 2008 |
Egan CE, Sukhumavasi W, Bierly AL, Denkers EY. Understanding the multiple functions of Gr-1(+) cell subpopulations during microbial infection. Immunologic Research. 40: 35-48. PMID 18193362 DOI: 10.1007/S12026-007-0061-8 |
0.798 |
|
| 2008 |
Egan CE, Sukhumavasi W, Butcher BA, Denkers EY. Functional Aspects of TLR-MyD88 Signaling During Protozoan Infection: Focus onToxoplasma gondii Clinical and Experimental Immunology. DOI: 10.1111/J.1365-2249.2008.03876.X |
0.796 |
|
| 2007 |
Lee CW, Sukhumavasi W, Denkers EY. Phosphoinositide-3-kinase-dependent, MyD88-independent induction of CC-type chemokines characterizes the macrophage response to Toxoplasma gondii strains with high virulence Infection and Immunity. 75: 5788-5797. PMID 17908814 DOI: 10.1128/Iai.00821-07 |
0.799 |
|
| 2007 |
Sukhumavasi W, Egan CE, Denkers EY. Mouse neutrophils require JNK2 MAPK for Toxoplasma gondii-induced IL-12p40 and CCL2/MCP-1 release. Journal of Immunology (Baltimore, Md. : 1950). 179: 3570-7. PMID 17785791 DOI: 10.4049/Jimmunol.179.6.3570 |
0.814 |
|
| 2006 |
Gazzinelli RT, Denkers EY. Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism. Nature Reviews. Immunology. 6: 895-906. PMID 17110955 DOI: 10.1038/Nri1978 |
0.471 |
|
| 2006 |
Kim L, Butcher BA, Lee CW, Uematsu S, Akira S, Denkers EY. Toxoplasma gondii genotype determines MyD88-dependent signaling in infected macrophages Journal of Immunology. 177: 2584-2591. PMID 16888020 DOI: 10.4049/Jimmunol.177.4.2584 |
0.804 |
|
| 2006 |
Bennouna S, Sukhumavasi W, Denkers EY. Toxoplasma gondii inhibits toll-like receptor 4 ligand-induced mobilization of intracellular tumor necrosis factor alpha to the surface of mouse peritoneal neutrophils. Infection and Immunity. 74: 4274-81. PMID 16790802 DOI: 10.1128/Iai.01573-05 |
0.806 |
|
| 2006 |
Kim L, Denkers EY. Toxoplasma gondii triggers Gi-dependent PI 3-kinase signaling required for inhibition of host cell apoptosis. Journal of Cell Science. 119: 2119-26. PMID 16638808 DOI: 10.1242/Jcs.02934 |
0.774 |
|
| 2006 |
Lee CW, Bennouna S, Denkers EY. Screening for Toxoplasma gondii-regulated transcriptional responses in lipopolysaccharide-activated macrophages Infection and Immunity. 74: 1916-1923. PMID 16495567 DOI: 10.1128/Iai.74.3.1916-1923.2006 |
0.853 |
|
| 2005 |
Butcher BA, Greene RI, Henry SC, Annecharico KL, Weinberg JB, Denkers EY, Sher A, Taylor GA. p47 GTPases regulate Toxoplasma gondii survival in activated macrophages. Infection and Immunity. 73: 3278-86. PMID 15908352 DOI: 10.1128/Iai.73.6.3278-3286.2005 |
0.493 |
|
| 2005 |
Bennouna S, Denkers EY. Microbial antigen triggers rapid mobilization of TNF-alpha to the surface of mouse neutrophils transforming them into inducers of high-level dendritic cell TNF-alpha production. Journal of Immunology (Baltimore, Md. : 1950). 174: 4845-51. PMID 15814711 DOI: 10.4049/Jimmunol.174.8.4845 |
0.824 |
|
| 2005 |
Kim L, Del Rio L, Butcher BA, Mogensen TH, Paludan SR, Flavell RA, Denkers EY. p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infection. Journal of Immunology (Baltimore, Md. : 1950). 174: 4178-84. PMID 15778378 DOI: 10.4049/Jimmunol.174.7.4178 |
0.771 |
|
| 2005 |
Butcher BA, Kim L, Panopoulos AD, Watowich SS, Murray PJ, Denkers EY. IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages. Journal of Immunology (Baltimore, Md. : 1950). 174: 3148-52. PMID 15749841 DOI: 10.4049/Jimmunol.174.6.3148 |
0.809 |
|
| 2005 |
Denkers EY, Butcher BA. Sabotage and exploitation in macrophages parasitized by intracellular protozoans. Trends in Parasitology. 21: 35-41. PMID 15639739 DOI: 10.1016/J.Pt.2004.10.004 |
0.521 |
|
| 2005 |
Kim L, Butcher B, Denkers E. Playing with Fire: Manipulation of Macrophage Proinflammatory Signal Transduction by the Intracellular Protozoan Toxoplasma gondii Current Immunology Reviews. 1: 213-222. DOI: 10.2174/157339505774479220 |
0.746 |
|
| 2004 |
Denkers EY, Butcher BA, Del Rio L, Kim L. Manipulation of mitogen-activated protein kinase/nuclear factor-kappaB-signaling cascades during intracellular Toxoplasma gondii infection. Immunological Reviews. 201: 191-205. PMID 15361242 DOI: 10.1111/J.0105-2896.2004.00180.X |
0.808 |
|
| 2004 |
Del Rio L, Butcher BA, Bennouna S, Hieny S, Sher A, Denkers EY. Toxoplasma gondii triggers myeloid differentiation factor 88-dependent IL-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct parasite molecules and host receptors. Journal of Immunology (Baltimore, Md. : 1950). 172: 6954-60. PMID 15153515 DOI: 10.4049/Jimmunol.172.11.6954 |
0.832 |
|
| 2004 |
Denkers EY, Butcher BA, Del Rio L, Bennouna S. Neutrophils, dendritic cells and Toxoplasma. International Journal For Parasitology. 34: 411-21. PMID 15003500 DOI: 10.1016/J.Ijpara.2003.11.001 |
0.859 |
|
| 2004 |
Kim L, Butcher BA, Denkers EY. Toxoplasma gondii interferes with lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance. Journal of Immunology (Baltimore, Md. : 1950). 172: 3003-10. PMID 14978104 DOI: 10.4049/Jimmunol.172.5.3003 |
0.778 |
|
| 2004 |
Gavrilescu LC, Butcher BA, Del Rio L, Taylor GA, Denkers EY. STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection. Infection and Immunity. 72: 1257-64. PMID 14977926 DOI: 10.1128/Iai.72.3.1257-1264.2004 |
0.834 |
|
| 2003 |
Denkers EY. From cells to signaling cascades: manipulation of innate immunity by Toxoplasma gondii. Fems Immunology and Medical Microbiology. 39: 193-203. PMID 14642303 DOI: 10.1016/S0928-8244(03)00279-7 |
0.631 |
|
| 2003 |
Bennouna S, Bliss SK, Curiel TJ, Denkers EY. Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection. Journal of Immunology (Baltimore, Md. : 1950). 171: 6052-8. PMID 14634118 DOI: 10.4049/Jimmunol.171.11.6052 |
0.847 |
|
| 2003 |
Gavrilescu LC, Denkers EY. Apoptosis and the balance of homeostatic and pathologic responses to protozoan infection. Infection and Immunity. 71: 6109-15. PMID 14573625 DOI: 10.1128/Iai.71.11.6109-6115.2003 |
0.775 |
|
| 2003 |
Denkers EY, Del Rio L, Bennouna S. Neutrophil production of IL-12 and other cytokines during microbial infection. Chemical Immunology and Allergy. 83: 95-114. PMID 12947981 DOI: 10.1159/000071557 |
0.831 |
|
| 2003 |
Gavrilescu LC, Denkers EY. Interleukin-12 p40- and Fas ligand-dependent apoptotic pathways involving STAT-1 phosphorylation are triggered during infection with a virulent strain of Toxoplasma gondii. Infection and Immunity. 71: 2577-83. PMID 12704131 DOI: 10.1128/Iai.71.5.2577-2583.2003 |
0.836 |
|
| 2003 |
Denkers EY, Kim L, Butcher BA. In the belly of the beast: subversion of macrophage proinflammatory signalling cascades during Toxoplasma gondii infection. Cellular Microbiology. 5: 75-83. PMID 12580944 DOI: 10.1046/J.1462-5822.2003.00258.X |
0.838 |
|
| 2003 |
Straw AD, MacDonald AS, Denkers EY, Pearce EJ. CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses. Journal of Immunology (Baltimore, Md. : 1950). 170: 727-34. PMID 12517934 DOI: 10.4049/Jimmunol.170.2.727 |
0.811 |
|
| 2002 |
Butcher BA, Denkers EY. Mechanism of entry determines the ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production. Infection and Immunity. 70: 5216-24. PMID 12183573 DOI: 10.1128/Iai.70.9.5216-5224.2002 |
0.548 |
|
| 2002 |
Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A. Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 5997-6001. PMID 12055206 DOI: 10.4049/Jimmunol.168.12.5997 |
0.843 |
|
| 2001 |
Del Rio L, Bennouna S, Salinas J, Denkers EY. CXCR2 deficiency confers impaired neutrophil recruitment and increased susceptibility during Toxoplasma gondii infection. Journal of Immunology (Baltimore, Md. : 1950). 167: 6503-9. PMID 11714818 DOI: 10.4049/Jimmunol.167.11.6503 |
0.847 |
|
| 2001 |
Butcher BA, Kim L, Johnson PF, Denkers EY. Toxoplasma gondii tachyzoites inhibit proinflammatory cytokine induction in infected macrophages by preventing nuclear translocation of the transcription factor NF-kappa B. Journal of Immunology (Baltimore, Md. : 1950). 167: 2193-201. PMID 11490005 DOI: 10.4049/Jimmunol.167.4.2193 |
0.806 |
|
| 2001 |
Bliss SK, Gavrilescu LC, Alcaraz A, Denkers EY. Neutrophil depletion during Toxoplasma gondii infection leads to impaired immunity and lethal systemic pathology. Infection and Immunity. 69: 4898-905. PMID 11447166 DOI: 10.1128/Iai.69.8.4898-4905.2001 |
0.852 |
|
| 2001 |
Gavrilescu LC, Denkers EY. IFN-gamma overproduction and high level apoptosis are associated with high but not low virulence Toxoplasma gondii infection. Journal of Immunology (Baltimore, Md. : 1950). 167: 902-9. PMID 11441097 DOI: 10.4049/Jimmunol.167.2.902 |
0.825 |
|
| 2001 |
Araujo MI, Bliss SK, Suzuki Y, Alcaraz A, Denkers EY, Pearce EJ. Interleukin-12 promotes pathologic liver changes and death in mice coinfected with Schistosoma mansoni and Toxoplasma gondii. Infection and Immunity. 69: 1454-62. PMID 11179312 DOI: 10.1128/Iai.69.3.1454-1462.2001 |
0.814 |
|
| 2000 |
Bliss SK, Butcher BA, Denkers EY. Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection. Journal of Immunology (Baltimore, Md. : 1950). 165: 4515-21. PMID 11035091 DOI: 10.4049/Jimmunol.165.8.4515 |
0.809 |
|
| 1999 |
Denkers EY. T lymphocyte-dependent effector mechanisms of immunity to Toxoplasma gondii Microbes and Infection. 1: 699-708. PMID 10611747 DOI: 10.1016/S1286-4579(99)80071-9 |
0.55 |
|
| 1999 |
Zhang Y, Denkers EY. Protective role for interleukin-5 during chronic Toxoplasma gondii infection Infection and Immunity. 67: 4383-4392. PMID 10456878 DOI: 10.1128/Iai.67.9.4383-4392.1999 |
0.515 |
|
| 1999 |
Marshall AJ, Brunet LR, van Gessel Y, Alcaraz A, Bliss SK, Pearce EJ, Denkers EY. Toxoplasma gondii and Schistosoma mansoni synergize to promote hepatocyte dysfunction associated with high levels of plasma TNF-alpha and early death in C57BL/6 mice. Journal of Immunology (Baltimore, Md. : 1950). 163: 2089-97. PMID 10438948 |
0.791 |
|
| 1999 |
Bliss SK, Zhang Y, Denkers EY. Murine neutrophil stimulation by Toxoplasma gondii antigen drives high level production of IFN-gamma-independent IL-12. Journal of Immunology (Baltimore, Md. : 1950). 163: 2081-8. PMID 10438947 |
0.815 |
|
| 1999 |
Bliss SK, Marshall AJ, Zhang Y, Denkers EY. Human polymorphonuclear leukocytes produce IL-12, TNF-alpha, and the chemokines macrophage-inflammatory protein-1 alpha and -1 beta in response to Toxoplasma gondii antigens. Journal of Immunology (Baltimore, Md. : 1950). 162: 7369-75. PMID 10358188 |
0.784 |
|
| 1999 |
Zhang Y, Denkers EY. Protective Role for Interleukin-5 during Chronic Toxoplasma gondii Infection Infection and Immunity. 67: 4383-4392. DOI: 10.1128/iai.67.9.4383-4392.1999 |
0.42 |
|
| 1998 |
Denkers EY, Gazzinelli RT. Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection Clinical Microbiology Reviews. 11: 569-588. PMID 9767056 DOI: 10.1128/Cmr.11.4.569 |
0.565 |
|
| 1998 |
Marshall AJ, Denkers EY. Toxoplasma gondii triggers granulocyte-dependent cytokine-mediated lethal shock in D-galactosamine-sensitized mice. Infection and Immunity. 66: 1325-33. PMID 9529049 DOI: 10.1128/Iai.66.4.1325-1333.1998 |
0.433 |
|
| 1998 |
Denkers EY, Marshall AJ. Neutrophils as a source of immunoregulatory cytokines during microbial infection Immunologist. 6: 116-120. |
0.459 |
|
| 1997 |
Denkers EY, Yap G, Scharton-Kersten T, Charest H, Butcher BA, Caspar P, Heiny S, Sher A. Perforin-Mediated Cytolysis Plays a Limited Role in Host Resistance to Toxoplasma gondii Journal of Immunology. 159: 1903-1908. PMID 9257855 |
0.355 |
|
| 1997 |
Denkers EY, Sher A. Role of natural killer and NK1+ T-cells in regulating cell-mediated immunity during Toxoplasma gondii infection Biochemical Society Transactions. 25: 699-703. PMID 9191186 DOI: 10.1042/Bst0250699 |
0.504 |
|
| 1996 |
Denkers EY. A Toxoplasma gondii superantigen: Biological effects and implications for the host-parasite interaction Parasitology Today. 12: 362-366. PMID 15275175 DOI: 10.1016/0169-4758(96)10028-4 |
0.481 |
|
| 1996 |
Scharton-Kersten T, Caspar P, Sher A, Denkers EY. Toxoplasma gondii: Evidence for interleukin-12-dependent and -independent pathways of interferon-γ production induced by an attenuated parasite strain Experimental Parasitology. 84: 102-114. PMID 8932760 DOI: 10.1006/Expr.1996.0096 |
0.547 |
|
| 1996 |
Scharton-Kersten TM, Wynn TA, Denkers EY, Bala S, Grunvald E, Hieny S, Gazzinelli RT, Sher A. In the Absence of Endogenous IFN-γ, Mice Develop Unimpaired IL-12 Responses to Toxoplasma gondii while Failing to Control Acute Infection Journal of Immunology. 157: 4045-4054. PMID 8892638 |
0.43 |
|
| 1996 |
Denkers EY, Scharton-Kersten T, Barbieri S, Caspar P, Sher A. A role for CD4+NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection Journal of Experimental Medicine. 184: 131-139. PMID 8691126 DOI: 10.1084/Jem.184.1.131 |
0.486 |
|
| 1996 |
Denkers EY, Caspar P, Hieny S, Sher A. Toxoplasma gondii infection induces specific nonresponsiveness in lymphocytes bearing the Vβ5 chain of the mouse T cell receptor Journal of Immunology. 156: 1089-1094. PMID 8557983 |
0.426 |
|
| 1996 |
Denkers EY, Yap G, Charest H, Scharton-Karsten T, Butcher BA, Sher A. Perforin knockout mice retain cd8+ t lymphocyte immunity to toxoplasma gondii despite absence of parasite-specific ctl function Faseb Journal. 10. |
0.416 |
|
| 1995 |
Scharton-Kersten T, Denkers EY, Gazzinelli R, Sher A. Role of IL 12 in induction of cell-mediated immunity to Toxoplasma gondii Research in Immunology. 146: 539-545. PMID 8839159 DOI: 10.1016/0923-2494(96)83029-X |
0.474 |
|
| 1995 |
Sher A, Denkers EY, Gazzinelli RT. Induction and regulation of host cell-mediated immunity by Toxoplasma gondii Ciba Foundation Symposium. 195. PMID 8724832 |
0.481 |
|
| 1994 |
Denkers EY, Caspar P, Sher A. Toxoplasma gondii possesses a superantigen activity that selectively expands murine T cell receptor Vβ5-bearing CD8+ lymphocytes Journal of Experimental Medicine. 180: 985-994. PMID 8064244 DOI: 10.1084/Jem.180.3.985 |
0.498 |
|
| 1994 |
Gazzinelli RT, Wysocka M, Hayashi S, Denkers EY, Hieny S, Caspar P, Trinchieri G, Sher A. Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii Journal of Immunology. 153: 2533-2543. PMID 7915739 |
0.443 |
|
| 1993 |
Denkers EY, Gazzinelli RT, Martin D, Sher A. Emergence of NK1.1+ cells as effectors of IFN-γ dependent immunity to Toxoplasma gondii in MHC class I-deficient mice Journal of Experimental Medicine. 178: 1465-1472. PMID 8228800 DOI: 10.1084/Jem.178.5.1465 |
0.461 |
|
| 1993 |
Denkers EY, Sher A, Gazzinelli RT. CD8+ T-cell interactions with Toxoplasma gondii: implications for processing of antigen for class-I-restricted recognition Research in Immunology. 144: 51-57. PMID 8095730 DOI: 10.1016/S0923-2494(05)80099-9 |
0.428 |
|
| 1993 |
Gazzinelli RT, Denkers EY, Sher A. Host resistance to Toxoplasma gondii: Model for studying the selective induction of cell-mediated immunity by intracellular parasites Infectious Agents and Disease. 2: 139-149. PMID 7909708 |
0.331 |
|
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