| Year |
Citation |
Score |
| 2017 |
McDonald MG, Ray S, Amorosi CJ, Sitko KA, Kowalski JP, Paco L, Nath A, Gallis BM, Totah RA, Dunham MJ, Fowler DM, Rettie AE. Expression and functional characterization of breast cancer-associated cytochrome P450 4Z1 in Saccharomyces cerevisiae. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29018033 DOI: 10.1124/Dmd.117.078188 |
0.359 |
|
| 2015 |
Johnson AL, Edson KZ, Totah RA, Rettie AE. Cytochrome P450 ω-Hydroxylases in Inflammation and Cancer. Advances in Pharmacology (San Diego, Calif.). 74: 223-62. PMID 26233909 DOI: 10.1016/Bs.Apha.2015.05.002 |
0.379 |
|
| 2014 |
Kaspera R, Kirby BJ, Sahele T, Collier AC, Kharasch ED, Unadkat JD, Totah RA. Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo. Biochemical Pharmacology. 91: 109-18. PMID 24973543 DOI: 10.1016/J.Bcp.2014.06.020 |
0.352 |
|
| 2012 |
Floyd JS, Kaspera R, Marciante KD, Weiss NS, Heckbert SR, Lumley T, Wiggins KL, Tamraz B, Kwok PY, Totah RA, Psaty BM. A screening study of drug-drug interactions in cerivastatin users: An adverse effect of clopidogrel Clinical Pharmacology and Therapeutics. 91: 896-904. PMID 22419147 DOI: 10.1038/Clpt.2011.295 |
0.321 |
|
| 2012 |
Lee CA, Jones JP, Katayama J, Kaspera R, Jiang Y, Freiwald S, Smith E, Walker GS, Totah RA. Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 943-51. PMID 22328583 DOI: 10.1124/Dmd.111.043505 |
0.381 |
|
| 2012 |
Kaspera R, Sahele T, Lakatos K, Totah RA. Cytochrome P450BM-3 reduces aldehydes to alcohols through a direct hydride transfer. Biochemical and Biophysical Research Communications. 418: 464-8. PMID 22281497 DOI: 10.1016/J.Bbrc.2012.01.040 |
0.302 |
|
| 2012 |
Raccor BS, Claessens AJ, Dinh JC, Park JR, Hawkins DS, Thomas SS, Makar KW, McCune JS, Totah RA. Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 54-63. PMID 21976622 DOI: 10.1124/Dmd.111.039347 |
0.346 |
|
| 2010 |
Kaspera R, Naraharisetti SB, Tamraz B, Sahele T, Cheesman MJ, Kwok PY, Marciante K, Heckbert SR, Psaty BM, Totah RA. Cerivastatin in vitro metabolism by CYP2C8 variants found in patients experiencing rhabdomyolysis. Pharmacogenetics and Genomics. 20: 619-29. PMID 20739906 DOI: 10.1097/Fpc.0B013E32833Ecace |
0.38 |
|
| 2010 |
Suresh BN, Lin YS, Rieder MJ, Marciante KD, Psaty BM, Thummel KE, Totah RA. Human liver expression of CYP2C8: Gender, age, and genotype effects Drug Metabolism and Disposition. 38: 889-893. PMID 20190184 DOI: 10.1124/Dmd.109.031542 |
0.323 |
|
| 2010 |
Lee CA, Neul D, Clouser-Roche A, Dalvie D, Wester MR, Jiang Y, Jones JP, Freiwald S, Zientek M, Totah RA. Identification of novel substrates for human cytochrome P450 2J2. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 347-56. PMID 19923256 DOI: 10.1124/Dmd.109.030270 |
0.383 |
|
| 2009 |
Kaspera R, Totah RA. Epoxyeicosatrienoic acids: formation, metabolism and potential role in tissue physiology and pathophysiology. Expert Opinion On Drug Metabolism & Toxicology. 5: 757-71. PMID 19505190 DOI: 10.1517/17425250902932923 |
0.337 |
|
| 2008 |
Smith HE, Jones JP, Kalhorn TF, Farin FM, Stapleton PL, Davis CL, Perkins JD, Blough DK, Hebert MF, Thummel KE, Totah RA. Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease. Pharmacogenetics and Genomics. 18: 943-53. PMID 18769365 DOI: 10.1097/Fpc.0B013E32830E1E16 |
0.323 |
|
| 2008 |
Totah RA, Sheffels P, Roberts T, Whittington D, Thummel K, Kharasch ED. Role of CYP2B6 in stereoselective human methadone metabolism. Anesthesiology. 108: 363-74. PMID 18292673 DOI: 10.1097/Aln.0B013E3181642938 |
0.363 |
|
| 2007 |
Totah RA, Allen KE, Sheffels P, Whittington D, Kharasch ED. Enantiomeric metabolic interactions and stereoselective human methadone metabolism. The Journal of Pharmacology and Experimental Therapeutics. 321: 389-99. PMID 17259447 DOI: 10.1124/Jpet.106.117580 |
0.376 |
|
| 2005 |
Totah RA, Rettie AE. Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance. Clinical Pharmacology and Therapeutics. 77: 341-52. PMID 15900280 DOI: 10.1016/J.Clpt.2004.12.267 |
0.334 |
|
| 2004 |
Huang W, Lin YS, McConn DJ, Calamia JC, Totah RA, Isoherranen N, Glodowski M, Thummel KE. Evidence of significant contribution from CYP3A5 to hepatic drug metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1434-45. PMID 15383492 DOI: 10.1124/Dmd.104.001313 |
0.398 |
|
| 2004 |
Totah RA, Hanzlik RP. Oxidative and nonoxidative decarboxylation of N-Alkyl-N-phenylglycines by horseradish peroxidase. Mechanistic switching by varying hydrogen peroxide, oxygen, and solvent deuterium. Biochemistry. 43: 7907-14. PMID 15196035 DOI: 10.1021/Bi049499Q |
0.512 |
|
| 2002 |
Totah RA, Hanzlik RP. Non-oxidative decarboxylation of glycine derivatives by a peroxidase. Journal of the American Chemical Society. 124: 10000-1. PMID 12188659 DOI: 10.1021/Ja020559U |
0.535 |
|
| 2001 |
Totah RA, Hanzlik RP. Detection of aminium ion intermediates: N-cyclopropyl versus N-carboxymethyl groups as reporters. Journal of the American Chemical Society. 123: 10107-8. PMID 11592894 DOI: 10.1021/Ja011648U |
0.493 |
|
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