Barbara H. Iglewski - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Microbiology Biology

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Filiatrault MJ, Tombline G, Wagner VE, Van Alst N, Rumbaugh K, Sokol P, Schwingel J, Iglewski BH. Pseudomonas aeruginosa PA1006, which plays a role in molybdenum homeostasis, is required for nitrate utilization, biofilm formation, and virulence. Plos One. 8: e55594. PMID 23409004 DOI: 10.1371/Journal.Pone.0055594  0.435
2013 Tombline G, Schwingel JM, Lapek JD, Friedman AE, Darrah T, Maguire M, Van Alst NE, Filiatrault MJ, Iglewski BH. Pseudomonas aeruginosa PA1006 is a persulfide-modified protein that is critical for molybdenum homeostasis. Plos One. 8: e55593. PMID 23409003 DOI: 10.1371/Journal.Pone.0055593  0.362
2009 Van Alst NE, Wellington M, Clark VL, Haidaris CG, Iglewski BH. Nitrite reductase NirS is required for type III secretion system expression and virulence in the human monocyte cell line THP-1 by Pseudomonas aeruginosa. Infection and Immunity. 77: 4446-54. PMID 19651860 DOI: 10.1128/Iai.00822-09  0.43
2008 Wagner VE, Iglewski BH. P. aeruginosa Biofilms in CF Infection. Clinical Reviews in Allergy & Immunology. 35: 124-34. PMID 18509765 DOI: 10.1007/S12016-008-8079-9  0.369
2007 Morici LA, Carterson AJ, Wagner VE, Frisk A, Schurr JR, Zu Bentrup KH, Hassett DJ, Iglewski BH, Sauer K, Schurr MJ. Pseudomonas aeruginosa AlgR represses the Rhl quorum-sensing system in a biofilm-specific manner Journal of Bacteriology. 189: 7752-7764. PMID 17766417 DOI: 10.1128/Jb.01797-06  0.43
2007 Van Alst NE, Picardo KF, Iglewski BH, Haidaris CG. Nitrate sensing and metabolism modulate motility, biofilm formation, and virulence in Pseudomonas aeruginosa. Infection and Immunity. 75: 3780-90. PMID 17526746 DOI: 10.1128/Iai.00201-07  0.42
2007 Li LL, Malone JE, Iglewski BH. Regulation of the Pseudomonas aeruginosa quorum-sensing regulator VqsR. Journal of Bacteriology. 189: 4367-74. PMID 17449616 DOI: 10.1128/Jb.00007-07  0.616
2007 Wagner VE, Li LL, Isabella VM, Iglewski BH. Analysis of the hierarchy of quorum-sensing regulation in Pseudomonas aeruginosa. Analytical and Bioanalytical Chemistry. 387: 469-79. PMID 17139483 DOI: 10.1007/S00216-006-0964-6  0.622
2006 Matsui H, Wagner VE, Hill DB, Schwab UE, Rogers TD, Button B, Taylor RM, Superfine R, Rubinstein M, Iglewski BH, Boucher RC. A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms. Proceedings of the National Academy of Sciences of the United States of America. 103: 18131-6. PMID 17116883 DOI: 10.1073/Pnas.0606428103  0.354
2006 Filiatrault MJ, Picardo KF, Ngai H, Passador L, Iglewski BH. Identification of Pseudomonas aeruginosa genes involved in virulence and anaerobic growth. Infection and Immunity. 74: 4237-45. PMID 16790798 DOI: 10.1128/Iai.02014-05  0.423
2006 Wagner VE, Frelinger JG, Barth RK, Iglewski BH. Quorum sensing: dynamic response of Pseudomonas aeruginosa to external signals. Trends in Microbiology. 14: 55-8. PMID 16406629 DOI: 10.1016/J.Tim.2005.12.002  0.322
2005 Gillis RJ, White KG, Choi KH, Wagner VE, Schweizer HP, Iglewski BH. Molecular basis of azithromycin-resistant Pseudomonas aeruginosa biofilms Antimicrobial Agents and Chemotherapy. 49: 3858-3867. PMID 16127063 DOI: 10.1128/Aac.49.9.3858-3867.2005  0.384
2005 Filiatrault MJ, Wagner VE, Bushnell D, Haidaris CG, Iglewski BH, Passador L. Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa Infection and Immunity. 73: 3764-3772. PMID 15908409 DOI: 10.1128/Iai.73.6.3764-3772.2005  0.372
2005 Imamura Y, Higashiyama Y, Tomono K, Izumikawa K, Yanagihara K, Ohno H, Miyazaki Y, Hirakata Y, Mizuta Y, Kadota J, Iglewski BH, Kohno S. Azithromycin exhibits bactericidal effects on Pseudomonas aeruginosa through interaction with the outer membrane. Antimicrobial Agents and Chemotherapy. 49: 1377-80. PMID 15793115 DOI: 10.1128/Aac.49.4.1377-1380.2005  0.313
2004 Gillis RJ, Iglewski BH. Azithromycin retards Pseudomonas aeruginosa biofilm formation. Journal of Clinical Microbiology. 42: 5842-5. PMID 15583321 DOI: 10.1128/Jcm.42.12.5842-5845.2004  0.327
2004 Wagner VE, Gillis RJ, Iglewski BH. Transcriptome analysis of quorum-sensing regulation and virulence factor expression in Pseudomonas aeruginosa. Vaccine. 22: S15-20. PMID 15576196 DOI: 10.1016/J.Vaccine.2004.08.011  0.43
2003 Lamb JR, Patel H, Montminy T, Wagner VE, Iglewski BH. Functional domains of the RhlR transcriptional regulator of Pseudomonas aeruginosa. Journal of Bacteriology. 185: 7129-39. PMID 14645272 DOI: 10.1128/Jb.185.24.7129-7139.2003  0.366
2003 Smith RS, Iglewski BH. Pseudomonas aeruginosa quorum sensing as a potential antimicrobial target. The Journal of Clinical Investigation. 112: 1460-5. PMID 14617745 DOI: 10.1172/Jci20364  0.305
2003 Wagner VE, Bushnell D, Passador L, Brooks AI, Iglewski BH. Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment. Journal of Bacteriology. 185: 2080-95. PMID 12644477 DOI: 10.1128/Jb.185.7.2080-2095.2003  0.434
2002 Yoon SS, Hennigan RF, Hilliard GM, Ochsner UA, Parvatiyar K, Kamani MC, Allen HL, DeKievit TR, Gardner PR, Schwab U, Rowe JJ, Iglewski BH, McDermott TR, Mason RP, Wozniak DJ, et al. Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis. Developmental Cell. 3: 593-603. PMID 12408810 DOI: 10.1016/S1534-5807(02)00295-2  0.365
2002 Smith RS, Kelly R, Iglewski BH, Phipps RP. The Pseudomonas autoinducer N-(3-oxododecanoyl) homoserine lactone induces cyclooxygenase-2 and prostaglandin E2 production in human lung fibroblasts: implications for inflammation. Journal of Immunology (Baltimore, Md. : 1950). 169: 2636-42. PMID 12193735 DOI: 10.4049/Jimmunol.169.5.2636  0.351
2002 de Kievit TR, Kakai Y, Register JK, Pesci EC, Iglewski BH. Role of the Pseudomonas aeruginosa las and rhl quorum-sensing systems in rhlI regulation. Fems Microbiology Letters. 212: 101-6. PMID 12076794 DOI: 10.1016/S0378-1097(02)00735-8  0.424
2002 Smith RS, Harris SG, Phipps R, Iglewski B. The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)homoserine lactone contributes to virulence and induces inflammation in vivo. Journal of Bacteriology. 184: 1132-9. PMID 11807074 DOI: 10.1128/Jb.184.4.1132-1139.2002  0.359
2001 Smith RS, Fedyk ER, Springer TA, Mukaida N, Iglewski BH, Phipps RP. IL-8 production in human lung fibroblasts and epithelial cells activated by the Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone is transcriptionally regulated by NF-kappa B and activator protein-2. Journal of Immunology (Baltimore, Md. : 1950). 167: 366-74. PMID 11418672 DOI: 10.4049/Jimmunol.167.1.366  0.307
2001 De Kievit TR, Parkins MD, Gillis RJ, Srikumar R, Ceri H, Poole K, Iglewski BH, Storey DG. Multidrug efflux pumps: expression patterns and contribution to antibiotic resistance in Pseudomonas aeruginosa biofilms. Antimicrobial Agents and Chemotherapy. 45: 1761-70. PMID 11353623 DOI: 10.1128/Aac.45.6.1761-1770.2001  0.348
2001 De Kievit TR, Gillis R, Marx S, Brown C, Iglewski BH. Quorum-Sensing Genes in Pseudomonas aeruginosa Biofilms: Their Role and Expression Patterns Applied and Environmental Microbiology. 67: 1865-1873. PMID 11282644 DOI: 10.1128/Aem.67.4.1865-1873.2001  0.397
2001 Bollinger N, Hassett DJ, Iglewski BH, Costerton JW, McDermott TR. Gene expression in Pseudomonas aeruginosa: Evidence of iron override effects on quorum sensing and biofilm-specific gene regulation Journal of Bacteriology. 183: 1990-1996. PMID 11222597 DOI: 10.1128/Jb.183.6.1990-1996.2001  0.431
2001 Branny P, Pearson JP, Pesci EC, Köhler T, Iglewski BH, Van Delden C. Inhibition of quorum sensing by a Pseudomonas aeruginosa dksA homologue Journal of Bacteriology. 183: 1531-1539. PMID 11160083 DOI: 10.1128/Jb.183.5.1531-1539.2001  0.451
2000 De Kievit TR, Iglewski BH. Bacterial quorum sensing in pathogenic relationships Infection and Immunity. 68: 4839-4849. PMID 10948095 DOI: 10.1128/Iai.68.9.4839-4849.2000  0.368
2000 Rashid MH, Rumbaugh K, Passador L, Davies DG, Hamood AN, Iglewski BH, Kornberg A. Polyphosphate kinase is essential for biofilm development, quorum sensing, and virulence of Pseudomonas aeruginosa Proceedings of the National Academy of Sciences of the United States of America. 97: 9636-9641. PMID 10931957 DOI: 10.1073/Pnas.170283397  0.418
2000 Pearson JP, Feldman M, Iglewski BH, Prince A. Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infection Infection and Immunity. 68: 4331-4334. PMID 10858254 DOI: 10.1128/Iai.68.7.4331-4334.2000  0.404
2000 McKnight SL, Iglewski BH, Pesci EC. The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa. Journal of Bacteriology. 182: 2702-8. PMID 10781536 DOI: 10.1128/Jb.182.10.2702-2708.2000  0.407
1999 Kline T, Bowman J, Iglewski BH, De Kievit T, Kakai Y, Passador L. Novel synthetic analogs of the Pseudomonas autoinducer Bioorganic and Medicinal Chemistry Letters. 9: 3447-3452. PMID 10617089 DOI: 10.1016/S0960-894X(99)00626-5  0.365
1999 Hassett DJ, Ma JF, Elkins JG, McDermott TR, Ochsner UA, West SE, Huang CT, Fredericks J, Burnett S, Stewart PS, McFeters G, Passador L, Iglewski BH. Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide. Molecular Microbiology. 34: 1082-93. PMID 10594832 DOI: 10.1046/J.1365-2958.1999.01672.X  0.42
1999 De Kievit TR, Iglewski BH. Quorum sensing, gene expression, and Pseudomonas biofilms Methods in Enzymology. 310: 117-128. PMID 10547786 DOI: 10.1016/S0076-6879(99)10010-7  0.451
1999 Rumbaugh KP, Griswold JA, Iglewski BH, Hamood AN. Contribution of quorum sensing to the virulence of Pseudomonas aeruginosa in burn wound infections Infection and Immunity. 67: 5854-5862. PMID 10531240 DOI: 10.1128/Iai.67.11.5854-5862.1999  0.389
1999 Pesci EC, Milbank JB, Pearson JP, McKnight S, Kende AS, Greenberg EP, Iglewski BH. Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences of the United States of America. 96: 11229-34. PMID 10500159 DOI: 10.1073/Pnas.96.20.11229  0.379
1999 De Kievit T, Seed PC, Nezezon J, Passador L, Iglewski BH. RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa Journal of Bacteriology. 181: 2175-2184. PMID 10094696 DOI: 10.1128/Jb.181.7.2175-2184.1999  0.479
1999 Glessner A, Smith RS, Iglewski BH, Robinson JB. Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of twitching motility. Journal of Bacteriology. 181: 1623-9. PMID 10049396 DOI: 10.1128/Jb.181.5.1623-1629.1999  0.39
1999 Pearson JP, Van Delden C, Iglewski BH. Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals Journal of Bacteriology. 181: 1203-1210. PMID 9973347 DOI: 10.1128/Jb.181.4.1203-1210.1999  0.348
1998 Van Delden C, Pesci EC, Pearson JP, Iglewski BH. Starvation selection restores elastase and rhamnolipid production in a Pseudomonas aeruginosa quorum-sensing mutant Infection and Immunity. 66: 4499-4502. PMID 9712807 DOI: 10.1128/Iai.66.9.4499-4502.1998  0.419
1998 Davies DG, Parsek MR, Pearson JP, Iglewski BH, Costerton JW, Greenberg EP. The involvement of cell-to-cell signals in the development of a bacterial biofilm Science. 280: 295-298. PMID 9535661 DOI: 10.1126/Science.280.5361.295  0.36
1997 Pearson JP, Pesci EC, Iglewski BH. Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes Journal of Bacteriology. 179: 5756-5767. PMID 9294432 DOI: 10.1128/Jb.179.18.5756-5767.1997  0.468
1997 Preston MJ, Seed PC, Toder DS, Iglewski BH, Ohman DE, Gustin JK, Goldberg JB, Pier GB. Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections. Infection and Immunity. 65: 3086-90. PMID 9234758 DOI: 10.1128/Iai.65.8.3086-3090.1997  0.416
1997 Albus AM, Pesci EC, Runyen-Janecky LJ, West SE, Iglewski BH. Vfr controls quorum sensing in Pseudomonas aeruginosa. Journal of Bacteriology. 179: 3928-35. PMID 9190808 DOI: 10.1128/Jb.179.12.3928-3935.1997  0.453
1997 Pesci EC, Pearson JP, Seed PC, Iglewski BH. Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa Journal of Bacteriology. 179: 3127-3132. PMID 9150205 DOI: 10.1128/Jb.179.10.3127-3132.1997  0.432
1996 Passador L, Tucker KD, Guertin KR, Journet MP, Kende AS, Iglewski BH. Functional analysis of the Pseudomonas aeruginosa autoinducer PAI. Journal of Bacteriology. 178: 5995-6000. PMID 8830697 DOI: 10.1128/Jb.178.20.5995-6000.1996  0.346
1996 Rust L, Pesci EC, Iglewski BH. Analysis of the Pseudomonas aeruginosa elastase (lasB) regulatory region Journal of Bacteriology. 178: 1134-1140. PMID 8576049 DOI: 10.1128/Jb.178.4.1134-1140.1996  0.381
1996 Tang HB, Dimango E, Bryan R, Gambello M, Iglewski BH, Goldberg JB, Prince A. Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection Infection and Immunity. 64: 37-43. PMID 8557368 DOI: 10.1128/Iai.64.1.37-43.1996  0.415
1995 Pearson JP, Passador L, Iglewski BH, Greenberg EP. A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa Proceedings of the National Academy of Sciences of the United States of America. 92: 1490-1494. PMID 7878006 DOI: 10.1073/Pnas.92.5.1490  0.48
1995 Seed PC, Passador L, Iglewski BH. Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: An autoinduction regulatory hierarchy Journal of Bacteriology. 177: 654-659. PMID 7836299 DOI: 10.1128/Jb.177.3.654-659.1995  0.435
1994 Pearson JP, Gray KM, Passador L, Tucker KD, Eberhard A, Iglewski BH, Greenberg EP. Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes Proceedings of the National Academy of Sciences of the United States of America. 91: 197-201. PMID 8278364 DOI: 10.1073/Pnas.91.1.197  0.446
1994 Gray KM, Passador L, Iglewski BH, Greenberg EP. Interchangeability and specificity of components from the quorum-sensing regulatory systems of Vibrio fischeri and Pseudomonas aeruginosa Journal of Bacteriology. 176: 3076-3080. PMID 8188610 DOI: 10.1128/Jb.176.10.3076-3080.1994  0.45
1994 Toder DS, Ferrell SJ, Nezezon JL, Rust L, Iglewski BH. lasA and lasB genes of Pseudomonas aeruginosa: analysis of transcription and gene product activity. Infection and Immunity. 62: 1320-7. PMID 8132339 DOI: 10.1128/Iai.62.4.1320-1327.1994  0.43
1994 West SE, Kaye SA, Hamood AN, Iglewski BH. Characterization of Pseudomonas aeruginosa mutants that are deficient in exotoxin A synthesis and are altered in expression of regA, a positive regulator of exotoxin A. Infection and Immunity. 62: 897-903. PMID 8112861 DOI: 10.1128/Iai.62.3.897-903.1994  0.45
1993 Passador L, Cook JM, Gambello MJ, Rust L, Iglewski BH. Expression of Pseudomonas aeruginosa virulence genes requires cell-to- cell communication Science. 260: 1127-1130. PMID 8493556 DOI: 10.1126/Science.8493556  0.416
1993 Gambello MJ, Kaye S, Iglewski BH. LasR of Pseudomonas aeruginosa is a transcriptional activator of the alkaline protease gene (apr) and an enhancer of exotoxin A expression Infection and Immunity. 61: 1180-1184. PMID 8454322 DOI: 10.1128/Iai.61.4.1180-1184.1993  0.403
1992 Hamood AN, Ohman DE, West SE, Iglewski BH. Isolation and characterization of toxin A excretion-deficient mutants of Pseudomonas aeruginosa PAO1. Infection and Immunity. 60: 510-7. PMID 1730483 DOI: 10.1128/Iai.60.2.510-517.1992  0.348
1992 Wick MJ, Cook JM, Iglewski BH. Structure-function analysis of exotoxin A proteins with mutations at Histidine 426 Infection and Immunity. 60: 1128-1139. PMID 1541528 DOI: 10.1128/Iai.60.3.1128-1139.1992  0.345
1991 Storey DG, Raivio TL, Frank DW, Wick MJ, Kaye S, Iglewski BH. Effect of regB on expression from the P1 and P2 promoters of the Pseudomonas aeruginosa regAB operon. Journal of Bacteriology. 173: 6088-94. PMID 1917842 DOI: 10.1128/Jb.173.19.6088-6094.1991  0.644
1991 Gambello MJ, Iglewski BH. Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression Journal of Bacteriology. 173: 3000-3009. PMID 1902216 DOI: 10.1128/Jb.173.9.3000-3009.1991  0.424
1991 Toder DS, Gambello MJ, Iglewski BH. Pseudomonas aeruginosa LasA: a second elastase under the transcriptional control of lasR. Molecular Microbiology. 5: 2003-10. PMID 1766376 DOI: 10.1111/J.1365-2958.1991.Tb00822.X  0.43
1991 Frank DW, Iglewski BH. Cloning and sequence analysis of a trans-regulatory locus required for exoenzyme S synthesis in Pseudomonas aeruginosa. Journal of Bacteriology. 173: 6460-8. PMID 1655713 DOI: 10.1128/Jb.173.20.6460-6468.1991  0.634
1990 Mohr CD, Rust L, Albus AM, Iglewski BH, Deretic V. Expression patterns of genes encoding elastase and controlling mucoidy: Co-ordinate regulation of two virulence factors in Pseudomonas aeruginosa isolates from cystic fibrosis Molecular Microbiology. 4: 2103-2110. PMID 2128528 DOI: 10.1111/J.1365-2958.1990.Tb00571.X  0.468
1990 Wick MJ, Frank DW, Storey DG, Iglewski BH. Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A. Annual Review of Microbiology. 44: 335-63. PMID 2123620 DOI: 10.1146/Annurev.Mi.44.100190.002003  0.581
1990 Storey DG, Frank DW, Farinha MA, Kropinski AM, Iglewski BH. Multiple promoters control the regulation of the Pseudomonas aeruginosa regA gene. Molecular Microbiology. 4: 499-503. PMID 2113156 DOI: 10.1111/J.1365-2958.1990.Tb00616.X  0.632
1990 Wick MJ, Frank DW, Storey DG, Iglewski BH. Identification of regB, a gene required for optimal exotoxin A yields in Pseudomonas aeruginosa. Molecular Microbiology. 4: 489-97. PMID 2113155 DOI: 10.1111/J.1365-2958.1990.Tb00615.X  0.636
1990 Hamood AN, Wick MJ, Iglewski BH. Secretion of toxin A from Pseudomonas aeruginosa PAO1, PAK and PA103 by Escherichia coli Infection and Immunity. 58: 1133-1140. PMID 2108926 DOI: 10.1128/Iai.58.5.1133-1140.1990  0.379
1990 Hamood AN, Iglewski BH. Expression of the Pseudomonas aeruginosa toxA positive regulatory gene (regA) in Escherichia coli Journal of Bacteriology. 172: 589-594. PMID 2105298 DOI: 10.1128/Jb.172.2.589-594.1990  0.395
1989 Frank DW, Storey DG, Hindahl MS, Iglewski BH. Differential regulation by iron of regA and toxA transcript accumulation in Pseudomonas aeruginosa. Journal of Bacteriology. 171: 5304-13. PMID 2507519 DOI: 10.1128/Jb.171.10.5304-5313.1989  0.628
1989 Zimniak L, Dayn A, Iglewski BH. Identification of RegA protein from Pseudomonas aeruginosa using anti-RegA antibody Biochemical and Biophysical Research Communications. 163: 1312-1318. PMID 2506862 DOI: 10.1016/0006-291X(89)91121-2  0.398
1989 Hamood AN, Olson JC, Vincent TS, Iglewski BH. Regions of toxin A involved in toxin A excretion in Pseudomonas aeruginosa Journal of Bacteriology. 171: 1817-1824. PMID 2495264 DOI: 10.1128/Jb.171.4.1817-1824.1989  0.345
1988 Wick MJ, Iglewski BH. Determination of the amino acid change responsible for the nontoxic, cross-reactive exotoxin A protein (CRM 66) of Pseudomonas aeruginosa PAO-PR1 Journal of Bacteriology. 170: 5385-5388. PMID 3141388 DOI: 10.1128/Jb.170.11.5385-5388.1988  0.34
1988 Frank DW, Iglewski BH. Kinetics of toxA and regA mRNA accumulation in Pseudomonas aeruginosa. Journal of Bacteriology. 170: 4477-83. PMID 3139628 DOI: 10.1128/Jb.170.10.4477-4483.1988  0.61
1988 Hindahl MS, Frank DW, Hamood A, Iglewski BH. Characterization of a gene that regulates toxin A synthesis in Pseudomonas aeruginosa. Nucleic Acids Research. 16: 5699. PMID 3133641 DOI: 10.1093/Nar/16.12.5699  0.644
1988 West SE, Iglewski BH. Codon usage in Pseudomonas aeruginosa. Nucleic Acids Research. 16: 9323-35. PMID 2845370 DOI: 10.1093/Nar/16.19.9323  0.343
1988 Bever RA, Iglewski BH. Molecular characterization and nucleotide sequence of the Pseudomonas aeruginosa elastase structural gene Journal of Bacteriology. 170: 4309-4314. PMID 2842313 DOI: 10.1128/Jb.170.9.4309-4314.1988  0.382
1988 Schad PA, Iglewski BH. Nucleotide sequence and expression in Escherichia coli of the Pseudomonas aeruginosa lasA gene Journal of Bacteriology. 170: 2784-2789. PMID 2836371 DOI: 10.1128/Jb.170.6.2784-2789.1988  0.391
1987 Hindahl MS, Frank DW, Iglewski BH. Molecular studies of a positive regulator of toxin A synthesis in Pseudomonas aeruginosa. Antibiotics and Chemotherapy. 39: 279-89. PMID 3118790 DOI: 10.1159/000414353  0.61
1987 Elsheikh LE, Kronevi T, Wretlind B, Abaas S, Iglewski BH. Assessment of elastase as a Pseudomonas aeruginosa virulence factor in experimental lung infection in mink Veterinary Microbiology. 13: 281-289. PMID 3116751 DOI: 10.1016/0378-1135(87)90090-3  0.365
1987 Schad PA, Bever RA, Nicas TI, Leduc F, Hanne LF, Iglewski BH. Cloning and characterization of elastase genes from Pseudomonas aeruginosa Journal of Bacteriology. 169: 2691-2696. PMID 3034864 DOI: 10.1128/Jb.169.6.2691-2696.1987  0.436
1986 Nicas TI, Iglewski BH. Production of elastase and other exoproducts by environmental isolates of Pseudomonas aeruginosa Journal of Clinical Microbiology. 23: 967-969. PMID 3086372 DOI: 10.1128/Jcm.23.5.967-969.1986  0.347
1986 Woodruff WA, Parr TR, Hancock REW, Hanne LF, Nicas TI, Iglewski BH. Expression in Escherichia coli and function of Pseudomonas aeruginosa outer membrane porin protein F Journal of Bacteriology. 167: 473-479. PMID 3015873 DOI: 10.1128/Jb.167.2.473-479.1986  0.318
1985 Björklind A, Wretlind B, Möllegård I, Schad PA, Iglewski BH, Cox CD. Genetic mapping and characterization of Pseudomonas aeruginosa mutants that hyperproduce exoproteins. Journal of Bacteriology. 162: 1329-31. PMID 3922951 DOI: 10.1128/Jb.162.3.1329-1331.1985  0.352
1985 Nicas TI, Iglewski BH. Genetic approaches to study Pseudomonas aeruginosa protein antigens Advances in Experimental Medicine and Biology. 185: 223-232. PMID 3000148 DOI: 10.1007/978-1-4684-7974-4_15  0.421
1985 Nicas TI, Bradley J, Lochner JE, Iglewski BH. The role of exoenzyme S in infections with pseudomonas aeruginosa Journal of Infectious Diseases. 152: 716-721. PMID 2995500 DOI: 10.1093/Infdis/152.4.716  0.335
1985 Nicas TI, Frank DW, Stenzel P, Lile JD, Iglewski BH. Role of exoenzyme S in chronic Pseudomonas aeruginosa lung infections. European Journal of Clinical Microbiology. 4: 175-9. PMID 2988945 DOI: 10.1007/Bf02013593  0.595
1985 Nicas TI, Iglewski BH. The contribution of exoproducts to virulence of Pseudomonas aeruginosa Canadian Journal of Microbiology. 31: 387-392. PMID 2988728 DOI: 10.1139/M85-074  0.407
1985 Nicas TI, Iglewski BH. Contribution of exoenzyme S to the virulence of Pseudomonas aeruginosa Antibiotics and Chemotherapy. 36: 40-48. PMID 2988426 DOI: 10.1159/000410470  0.36
1984 Howe TR, Iglewski BH. Isolation and characterization of alkaline protease-deficient mutants of Pseudomonas aeruginosa in vitro and in a mouse eye model. Infection and Immunity. 43: 1058-63. PMID 6421735 DOI: 10.1128/Iai.43.3.1058-1063.1984  0.379
1984 Nicas TI, Iglewski BH. Isolation and characterization of transposon-induced mutants of Pseudomonas aeruginosa deficient in production of exoenzyme S Infection and Immunity. 45: 470-474. PMID 6086529 DOI: 10.1128/Iai.45.2.470-474.1984  0.417
1983 Cryz SJ, Iglewski BH. Toxoids of Pseudomonas aeruginosa toxin A: production by chemical and genetic means Reviews of Infectious Diseases. 5. PMID 6419321 DOI: 10.1093/Clinids/5.Supplement_5.S992  0.353
1983 Woods DE, Iglewski BH. Toxins of Pseudomonas aeruginosa: new perspectives Reviews of Infectious Diseases. 5. PMID 6415785 DOI: 10.1093/Clinids/5.Supplement_4.S715  0.402
1983 Hanne LF, Howe TR, Iglewski BH. Locus of the Pseudomonas aeruginosa toxin A gene. Journal of Bacteriology. 154: 383-6. PMID 6403508 DOI: 10.1128/Jb.154.1.383-386.1983  0.361
1983 Blackwood LL, Stone RM, Iglewski BH, Pennington JE. Evaluation of Pseudomonas aeruginosa exotoxin A and elastase as virulence factors in acute lung infection Infection and Immunity. 39: 198-201. PMID 6401692 DOI: 10.1128/Iai.39.1.198-201.1983  0.413
1983 Howe TR, Wretlind B, Iglewski BH. Comparison of two methods of genetic exchange in determination of the genetic locus of the structural gene for Pseudomonas aeruginosa elastase. Journal of Bacteriology. 156: 58-61. PMID 6311805 DOI: 10.1128/Jb.156.1.58-61.1983  0.318
1982 Friedman RL, Lochner JE, Bigley RH, Iglewski BH. The effects of Legionella pneumophila toxin on oxidative processes and bacterial killing of human polymorphonuclear leukocytes Journal of Infectious Diseases. 146: 328-334. PMID 7050255 DOI: 10.1093/Infdis/146.3.328  0.322
1982 Hazlett LD, Iglewski BH, Berk RS. Experimental Pseudomonas exotoxin A mediated ocular damage in mouse pups: Microscopic observations Ophthalmic Research. 14: 401-408. PMID 6819502 DOI: 10.1159/000265217  0.319
1982 Sokol PA, Cox CD, Iglewski BH. Pseudomonas aeruginosa mutants altered in their sensitivity to the effect of iron on toxin A or elastase yields. Journal of Bacteriology. 151: 783-7. PMID 6807961 DOI: 10.1128/Jb.151.2.783-787.1982  0.326
1982 Woods DE, Cryz SJ, Friedman RL, Iglewski BH. Contribution of toxin A and elastase to virulence of Pseudomonas aeruginosa in chronic lung infections of rats Infection and Immunity. 36: 1223-1228. PMID 6807846 DOI: 10.1128/Iai.36.3.1223-1228.1982  0.36
1982 Woods DE, Sokol PA, Iglewski BH. Modulatory effect of iron on the pathogenesis of Pseudomonas aeruginosa mouse corneal infections Infection and Immunity. 35: 461-464. PMID 6799404 DOI: 10.1128/Iai.35.2.461-464.1982  0.322
1982 Sadoff JC, Buck GA, Iglewski BH, Bjorn MJ, Groman NB. Immunological cross-reactivity in the absence of DNA homology between Pseudomonas toxin A and diphtheria toxin Infection and Immunity. 37: 250-254. PMID 6179878 DOI: 10.1128/Iai.37.1.250-254.1982  0.306
1981 Thompson MR, Miller RD, Iglewski BH. In vitro production of an extracellular protease by Legionella pneumophila Infection and Immunity. 34: 299-302. PMID 7028630 DOI: 10.1128/Iai.34.1.299-302.1981  0.328
1981 Hazlett LD, Berk RS, Iglewski BH. Microscopic characterization of ocular damage produced by Pseudomonas aeruginosa toxin A Infection and Immunity. 34: 1025-1035. PMID 6800950 DOI: 10.1128/Iai.34.3.1025-1035.1981  0.313
1981 Sokol PA, Iglewski BH, Hager TA, Sadoff JC, Cross AS, McManus A, Farber BF, Iglewski WJ. Production of exoenzyme S by clinical isolates of Pseudomonas aeruginosa Infection and Immunity. 34: 147-153. PMID 6271678 DOI: 10.1128/Iai.34.1.147-153.1981  0.371
1981 Cryz SJ, Friedman RL, Pavlovskis OR, Iglewski BH. Effect of formalin toxoiding on Pseudomonas aeruginosa toxin A: Biological, chemical, and immunochemical studies Infection and Immunity. 32: 759-768. PMID 6265363 DOI: 10.1128/Iai.32.2.759-768.1981  0.329
1980 Ohman DE, Burns RP, Iglewski BH. Corneal infections in mice with toxin a and elastase mutants of pseudomonas aeruginosa Journal of Infectious Diseases. 142: 547-555. PMID 6904461 DOI: 10.1093/Infdis/142.4.547  0.357
1980 Cryz SJ, Iglewski BH. Production of alkaline protease by Pseudomonas aeruginosa Journal of Clinical Microbiology. 12: 131-133. PMID 6775004 DOI: 10.1128/Jcm.12.1.131-133.1980  0.354
1980 Ohman DE, Cryz SJ, Iglewski BH. Isolation and characterization of a Pseudomonas aeruginosa PAO mutant that produces altered elastase Journal of Bacteriology. 142: 836-842. PMID 6769912 DOI: 10.1128/Jb.142.3.836-842.1980  0.367
1980 Cryz SJ, Friedman RL, Iglewski BH. Isolation and characterization of a Pseudomonas aeruginosa mutant producing a nontoxic, immunologically crossreactive toxin A protein Proceedings of the National Academy of Sciences of the United States of America. 77: 7199-7203. PMID 6261247 DOI: 10.1073/Pnas.77.12.7199  0.393
1979 Bjorn MJ, Pavlovskis OR, Thompson MR, Iglewski BH. Production of exoenzyme S during Pseudomonas aeruginosa infections of burned mice Infection and Immunity. 24: 837-842. PMID 112058 DOI: 10.1128/Iai.24.3.837-842.1979  0.344
1979 Bjorn MJ, Sokol PA, Iglewski BH. Influence of iron on yields of extracellular products in Pseudomonas aeruginosa cultures Journal of Bacteriology. 138: 193-200. PMID 108250 DOI: 10.1128/Jb.138.1.193-200.1979  0.344
1979 Iglewski BH, Sadoff JC. [69] Toxin Inhibitors of protein synthesis: production, purification, and assay of Pseudomonas aeruginosa toxin A Methods in Enzymology. 60: 780-793. DOI: 10.1016/S0076-6879(79)60071-X  0.338
1978 Pavlovskis OR, Iglewski BH, Pollack M. Mechanism of action of Pseudomonas aeruginosa exotoxin A in experimental mouse infections: adenosine diphosphate ribosylation of elongation factor 2 Infection and Immunity. 19: 29-33. PMID 415004 DOI: 10.1128/Iai.19.1.29-33.1978  0.352
1978 Iglewski BH, Sadoff J, Bjorn MJ, Maxwell ES. Pseudomonas aeruginosa exoenzyme S: an adenosine diphosphate ribosyltransferase distinct from toxin A Proceedings of the National Academy of Sciences of the United States of America. 75: 3211-3215. PMID 210453 DOI: 10.1073/Pnas.75.7.3211  0.323
1977 Pavlovskis OR, Pollack M, Callahan LT, Iglewski BH. Passive protection by antitoxin in experimental Pseudomonas aeruginosa burn infections Infection and Immunity. 18: 596-602. PMID 412786 DOI: 10.1128/Iai.18.3.596-602.1977  0.343
1977 Vasil ML, Kabat D, Iglewski BH. Structure activity relationships of an exotoxin of Pseudomonas aeruginosa Infection and Immunity. 16: 353-361. PMID 406204 DOI: 10.1128/Iai.16.1.353-361.1977  0.364
1977 Iglewski BH, Liu PV, Kabat D. Mechanism of action of Pseudomonas aeruginosa exotoxin A: adenosine diphosphate ribosylation of mammalian elongation factor 2 in vitro and in vivo Infection and Immunity. 15: 138-144. PMID 188760 DOI: 10.1128/Iai.15.1.138-144.1977  0.356
1977 Bjorn MJ, Vasil ML, Sadoff JC, Iglewski BH. Incidence of exotoxin production by Pseudomonas species Infection and Immunity. 16: 362-366. PMID 68931 DOI: 10.1128/Iai.16.1.362-366.1977  0.384
1976 Morse SA, Vaughan P, Johnson D, Iglewski BH. Inhibition of Neisseria gonorrhoeae by a bacteriocin from Pseudomonas aeruginosa Antimicrobial Agents and Chemotherapy. 10: 354-362. PMID 825024 DOI: 10.1128/Aac.10.2.354  0.348
1976 Vasil ML, Liu PV, Iglewski BH. Temperature dependent inactivating factor of Pseudomonas aeruginosa exotoxin A Infection and Immunity. 13: 1467-1472. PMID 178606 DOI: 10.1128/Iai.13.5.1467-1472.1976  0.329
1975 Iglewski BH, Kabat D. NAD dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin Proceedings of the National Academy of Sciences of the United States of America. 72: 2284-2288. PMID 166383 DOI: 10.1073/Pnas.72.6.2284  0.358
1974 Lightfoot HN, Iglewski BH. Synthesis of diphtheria toxin in E. coli cell-free lysate Biochemical and Biophysical Research Communications. 56: 351-357. PMID 4207356 DOI: 10.1016/0006-291X(74)90849-3  0.31
1972 Elwell LP, Iglewski BH. Diphtheria toxin: Evidence for presence of fragment B in corynebacteriophage Biochemical and Biophysical Research Communications. 49: 609-614. PMID 4629418 DOI: 10.1016/0006-291X(72)90454-8  0.306
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