Christopher M. Heaphy, Ph.D. - Publications

Affiliations: 
2008 University of New Mexico, Albuquerque, NM, United States 
Area:
Genetics, Oncology

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mori JO, Platz EA, Lu J, Brame A, Han M, Joshu CE, De Marzo AM, Meeker AK, Heaphy CM. Longer prostate stromal cell telomere length is associated with increased risk of death from other cancers. Frontiers in Medicine. 11: 1390769. PMID 38895181 DOI: 10.3389/fmed.2024.1390769  0.38
2023 Mori JO, Elhussin I, Brennen WN, Graham MK, Lotan TL, Yates CC, De Marzo AM, Denmeade SR, Yegnasubramanian S, Nelson WG, Denis GV, Platz EA, Meeker AK, Heaphy CM. Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer. Nature Reviews. Urology. PMID 37907729 DOI: 10.1038/s41585-023-00827-x  0.345
2023 Mori JO, Keegan J, Flynn RL, Heaphy CM. Alternative lengthening of telomeres: mechanism and the pathogenesis of cancer. Journal of Clinical Pathology. PMID 37890990 DOI: 10.1136/jcp-2023-209005  0.402
2023 Ertunc O, Smearman E, Zheng Q, Hicks JL, Brosnan-Cashman JA, Jones T, Gomes-Alexandre C, Trabzonlu L, Meeker AK, De Marzo AM, Heaphy CM. Chromogenic detection of telomere lengths in situ aids the identification of precancerous lesions in the prostate. Biorxiv : the Preprint Server For Biology. PMID 37066381 DOI: 10.1101/2023.04.04.535575  0.316
2022 Jafari N, Chen A, Kolla M, Pompa IR, Qiu Y, Yu R, Llevenes P, Ennis CS, Mori J, Mahdaviani K, Halpin M, Gignac GA, Heaphy CM, Monti S, Denis GV. Novel plasma exosome biomarkers for prostate cancer progression in co-morbid metabolic disease. Advances in Cancer Biology - Metastasis. 6. PMID 36644690 DOI: 10.1016/j.adcanc.2022.100073  0.372
2022 Low JY, Ko M, Hanratty B, Patel RA, Bhamidipati A, Heaphy CM, Sayar E, Lee JK, Li S, De Marzo AM, Nelson WG, Gupta A, Yegnasubramanian S, Ha G, Epstein JI, et al. Genomic Characterization of Prostatic Basal Cell Carcinoma. The American Journal of Pathology. PMID 36309102 DOI: 10.1016/j.ajpath.2022.09.010  0.319
2022 Heaphy CM, Joshu CE, Barber JR, Davis C, Lu J, Zarinshenas R, Giovannucci E, Mucci LA, Stampfer MJ, Han M, De Marzo AM, Lotan TL, Platz EA, Meeker AK. The prostate tissue-based telomere biomarker as a prognostic tool for metastasis and death from prostate cancer after prostatectomy. The Journal of Pathology. Clinical Research. PMID 35836303 DOI: 10.1002/cjp2.288  0.368
2021 Shrestha E, Coulter JB, Guzman W, Ozbek B, Hess MM, Mummert L, Ernst SE, Maynard JP, Meeker AK, Heaphy CM, Haffner MC, De Marzo AM, Sfanos KS. Oncogenic gene fusions in nonneoplastic precursors as evidence that bacterial infection can initiate prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34341114 DOI: 10.1073/pnas.2018976118  0.315
2020 Hempel Sullivan H, Maynard JP, Heaphy CM, Lu J, De Marzo AM, Lotan TL, Joshu CE, Sfanos KS. Differential mast cell phenotypes in benign versus cancer tissues and prostate cancer oncologic outcomes. The Journal of Pathology. PMID 33338262 DOI: 10.1002/path.5606  0.407
2020 Heaphy CM, Bi WL, Coy S, Davis C, Gallia GL, Santagata S, Rodriguez FJ. Telomere length alterations and ATRX/DAXX loss in pituitary adenomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 32203094 DOI: 10.1038/S41379-020-0523-2  0.336
2020 Hempel Sullivan H, Heaphy CM, Kulac I, Cuka N, Lu J, Barber JR, De Marzo AM, Lotan TL, Joshu CE, Sfanos KS. High Extra-tumoral Mast Cell Counts are Associated with a Higher Risk of Adverse Prostate Cancer Outcomes. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 31932412 DOI: 10.1158/1055-9965.Epi-19-0962  0.334
2020 Heaphy CM, Joshu CE, Barber JR, Davis C, Zarinshenas R, De Marzo AM, Lotan TL, Sfanos KS, Meeker AK, Platz EA. Racial difference in prostate cancer cell telomere lengths in men with higher-grade prostate cancer: a clue to the racial disparity in prostate cancer outcomes. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 31915143 DOI: 10.1158/1055-9965.Epi-19-1462  0.333
2020 Agurs-Collins T, Barber J, Bienstock J, Green P, Heaphy C, Lu J, Meeker A, Rizzo A, Rohrmann S, Platz E. Abstract C027: Racial variation in umbilical cord blood vitamin D concentrations and telomere length: Implications for cancer risk Cancer Epidemiology, Biomarkers & Prevention. DOI: 10.1158/1538-7755.Disp18-C027  0.3
2019 Graham MK, Kim J, Da J, Brosnan-Cashman JA, Rizzo A, Baena Del Valle JA, Chia L, Rubenstein M, Davis C, Zheng Q, Cope L, Considine M, Haffner MC, De Marzo AM, Meeker AK, ... Heaphy CM, et al. Functional loss of ATRX and TERC activates Alternative Lengthening of Telomeres (ALT) in LAPC4 prostate cancer cells. Molecular Cancer Research : McR. PMID 31611308 DOI: 10.1158/1541-7786.Mcr-19-0654  0.39
2019 Zarif JC, Baena-Del Valle JA, Hicks JL, Heaphy CM, Vidal I, Luo J, Lotan TL, Hooper JE, Isaacs WB, Pienta KJ, De Marzo AM. Mannose Receptor-positive Macrophage Infiltration Correlates with Prostate Cancer Onset and Metastatic Castration-resistant Disease. European Urology Oncology. 2: 429-436. PMID 31277779 DOI: 10.1016/J.Euo.2018.09.014  0.438
2019 Zarif JC, Valle JAB, Hicks JL, Heaphy CM, Vidal I, Luo J, Lotan TL, Hooper JE, Isaacs WB, Pienta KJ, Marzo AMD. Abstract 4582: Mannose receptor positive macrophage infiltrate correlates with prostate cancer onset and metastatic castration-resistant disease Cancer Research. 79: 4582-4582. DOI: 10.1158/1538-7445.Am2019-4582  0.443
2018 Marrone MT, Joshu CE, Peskoe SB, De Marzo AM, Heaphy CM, Lupold SE, Meeker AK, Platz EA. Adding the Team into T1 Translational Research: A Case Study of Multidisciplinary Team Science in the Evaluation of Biomarkers of Prostate Cancer Risk and Prognosis. Clinical Chemistry. PMID 30518666 DOI: 10.1373/Clinchem.2018.293365  0.389
2018 Brosnan-Cashman JA, Yuan M, Graham MK, Rizzo AJ, Myers KM, Davis C, Zhang R, Esopi DM, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner. Plos One. 13: e0204159. PMID 30226859 DOI: 10.1371/Journal.Pone.0204159  0.426
2018 Rodriguez FJ, Brosnan-Cashman JA, Allen SJ, Vizcaino MA, Giannini C, Camelo-Piragua S, Webb M, Matsushita M, Wadhwani N, Tabbarah A, Hamideh D, Jiang L, Chen L, Arvanitis LD, Alnajar HH, ... ... Heaphy CM, et al. Alternative lengthening of telomeres, ATRX loss and h3-k27m mutations in histologically defined pilocytic astrocytoma with anaplasia. Brain Pathology (Zurich, Switzerland). PMID 30192422 DOI: 10.1111/Bpa.12646  0.334
2018 Weber KA, Heaphy CM, Joshu CE, Lu J, Rohrmann S, Bienstock JL, Agurs-Collins T, Meeker AK, Platz EA. Racial differences in maternal and umbilical cord blood leukocyte telomere length and their correlations. Cancer Causes & Control : Ccc. PMID 29980985 DOI: 10.1007/S10552-018-1054-8  0.302
2018 Palsgrove DN, Brosnan-Cashman JA, Giannini C, Raghunathan A, Jentoft M, Bettegowda C, Gokden M, Lin D, Yuan M, Lin MT, Heaphy CM, Rodriguez FJ. Subependymal giant cell astrocytoma-like astrocytoma: a neoplasm with a distinct phenotype and frequent neurofibromatosis type-1-association. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 29973652 DOI: 10.1038/S41379-018-0103-X  0.41
2018 Bell WR, Meeker AK, Rizzo A, Rajpara S, Rosenthal IM, Flores Bellver M, Aparicio Domingo S, Zhong X, Barber JR, Joshu CE, Canto-Soler MV, Eberhart CG, Heaphy CM. A UNIQUE TELOMERE DNA EXPANSION PHENOTYPE IN HUMAN RETINAL ROD PHOTORECEPTORS ASSOCIATED WITH AGING AND DISEASE. Brain Pathology (Zurich, Switzerland). PMID 29668072 DOI: 10.1111/Bpa.12618  0.351
2018 Brosnan-Cashman JA, Graham MK, Rizzo AJ, Myers K, Zhang R, Göger E, Zarinshenas R, Davis C, Yuan M, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract B14: Establishment and characterization of in vitro models of alternative lengthening of telomeres (ALT) in pediatric high-grade glioma Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-B14  0.423
2018 Brosnan-Cashman JA, Heaphy CM, Meeker AK. Abstract 1467: Isolation and characterization of cancer cells containing ultrabright telomere DNA foci associated with alternative lengthening of telomeres (ALT): A novel utility for combined telomere-specific FISH and flow cytometry (Flow FISH) Cancer Research. 78: 1467-1467. DOI: 10.1158/1538-7445.Am2018-1467  0.482
2017 Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Mucci LA, Giovannucci EL, Stampfer MJ, Yoon G, Lee TK, Hicks JL, De Marzo AM, Meeker AK, Platz EA. Current or recent smoking is associated with more variable telomere length in prostate stromal cells and prostate cancer cells. The Prostate. PMID 29164645 DOI: 10.1002/Pros.23462  0.397
2017 Baena-Del Valle JA, Zheng Q, Esopi DM, Rubenstein M, Hubbard GK, Moncaliano MC, Hruszkewycz A, Vaghasia A, Yegnasubramanian S, Wheelan SJ, Meeker AK, Heaphy CM, Graham MK, De Marzo AM. MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer. The Journal of Pathology. PMID 28888037 DOI: 10.1002/Path.4980  0.468
2017 VandenBussche CJ, Allison DB, Graham MK, Charu V, Lennon AM, Wolfgang CL, Hruban RH, Heaphy CM. Alternative lengthening of telomeres and ATRX/DAXX loss can be reliably detected in FNAs of pancreatic neuroendocrine tumors. Cancer. PMID 28371511 DOI: 10.1002/Cncy.21857  0.382
2017 Becker AP, Bell EH, Fleming J, McElroy JP, Fabian D, Beyer S, Salavaggione AL, Graham MK, Heaphy CM, Oehlke O, Staszewski O, Prinz M, Grosu A, Chakravarti A. Comprehensive assessment of ATRX mutation, protein expression, and alternative lengthening of telomeres (ALT) phenotype in grade II and III gliomas. Journal of Clinical Oncology. 35: 2064-2064. DOI: 10.1200/Jco.2017.35.15_Suppl.2064  0.352
2017 Barry W, Heaphy C, Meeker A. Abstract 3470: The promyelocytic leukemia (PML) protein modulates rate and localization of homologous recombination in human cell lines with the alternative lengthening of telomeres (ALT) pathway Cancer Research. 77: 3470-3470. DOI: 10.1158/1538-7445.Am2017-3470  0.399
2017 Brosnan-Cashman JA, Rizzo AJ, Goger E, Myers KM, Zarinshenas R, Davis C, Yuan M, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract 3466: ALT-positive pediatric high grade glioma cells display chemosensitivity to ATR pathway inhibition Cancer Research. 77: 3466-3466. DOI: 10.1158/1538-7445.Am2017-3466  0.436
2017 Brosnan-Cashman JA, Yuan M, Rizzo AJ, Myers KM, Barry WT, Davis C, Esopi DM, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract 3465: Context-dependent effects of ATRX loss on telomere biology in glioma cells Cancer Research. 77: 3465-3465. DOI: 10.1158/1538-7445.Am2017-3465  0.467
2017 Rizzo AJ, Brosnan-Cashman JA, Graham MK, Meeker AK, Heaphy CM. Abstract 3464: CRISPR-mediated inactivation of ATRX and DAXX in pancreatic neuroendocrine tumor cell lines Cancer Research. 77: 3464-3464. DOI: 10.1158/1538-7445.Am2017-3464  0.478
2016 Weber KA, Heaphy CM, Rohrmann S, Gonzalez B, Bienstock JL, Agurs-Collins T, Platz EA, Meeker AK. Influence of In Utero Maternal and Neonate Factors on Cord Blood Leukocyte Telomere Length: Clues to the Racial Disparity in Prostate Cancer? Prostate Cancer. 2016: 3691650. PMID 28070423 DOI: 10.1155/2016/3691650  0.353
2016 Holdhoff M, Guner G, Rodriguez FJ, Hicks JL, Zheng Q, Forman MS, Ye X, Grossman SA, Meeker AK, Heaphy CM, Eberhart CG, De Marzo AM, Arav-Boger R. Absence of cytomegalovirus in glioblastoma and other high-grade gliomas by real-time PCR, immunohistochemistry and in situ hybridization. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28034905 DOI: 10.1158/1078-0432.Ccr-16-1490  0.317
2016 Kim JY, Brosnan-Cashman JA, An S, Kim SJ, Song KB, Kim MS, Kim MJ, Hwang DW, Meeker AK, Yu E, Kim SC, Hruban RH, Heaphy CM, Hong SM. Alternative lengthening of telomeres in primary pancreatic neuroendocrine neoplasms is associated with aggressive clinical behavior and poor survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27663587 DOI: 10.1158/1078-0432.Ccr-16-1147  0.36
2016 Hackeng WM, Brosens LA, Poruk KE, Noë M, Hosoda W, Poling JS, Rizzo A, Campbell-Thompson M, Atkinson MA, Konukiewitz B, Klöppel G, Heaphy CM, Meeker AK, Wood LD. Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis. Human Pathology. PMID 27342911 DOI: 10.1016/J.Humpath.2016.06.006  0.347
2016 Shekhani MT, Barber JR, Bezerra SM, Heaphy CM, Roibon ND, Taheri D, Reis LO, Guner G, Joshu CE, Netto GJ, Meeker AK. Hi-res telomere FISH reveals intriguing anomalies in germ cell tumors. Human Pathology. PMID 27085557 DOI: 10.1016/J.Humpath.2016.03.015  0.422
2016 Suryo Rahmanto Y, Jung JG, Wu RC, Kobayashi Y, Heaphy CM, Meeker AK, Wang TL, Shih IM. Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells. The Journal of Biological Chemistry. PMID 26953344 DOI: 10.1074/Jbc.M115.707612  0.397
2016 Valle JABD, Zheng Q, Rubenstein M, Meeker AK, Heaphy CM, Hubbard G, Bieberich CJ, Yegnasubramanian S, Esopi D, Wheelan SJ, Marzo AMD. Abstract LB-160: Human telomerase RNA component (hTR/TERC) is consistently overexpressed in prostate cancer, required for cell proliferation and is positively regulated by MYC Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-160  0.491
2016 Graham MK, Brosnan-Cashman J, Rizzo A, Haffner M, Meeker A, Heaphy C. Abstract 4767: Generating and characterizing novel prostate cancer cell lines that employ the alternative lengthening of telomeres (ALT) telomere maintenance mechanism Cancer Research. 76: 4767-4767. DOI: 10.1158/1538-7445.Am2016-4767  0.512
2015 Bodelon C, Heaphy CM, Meeker AK, Geller B, Vacek PM, Weaver DL, Chicoine RE, Shepherd JA, Mahmoudzadeh AP, Patel DA, Brinton LA, Sherman ME, Gierach GL. Leukocyte telomere length and its association with mammographic density and proliferative diagnosis among women undergoing diagnostic image-guided breast biopsy. Bmc Cancer. 15: 823. PMID 26519084 DOI: 10.1186/S12885-015-1860-2  0.391
2015 Cochran RL, Cidado J, Kim M, Zabransky DJ, Croessmann S, Chu D, Wong HY, Beaver JA, Cravero K, Erlanger B, Parsons H, Heaphy CM, Meeker AK, Lauring J, Park BH. Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes. Oncotarget. PMID 26246475 DOI: 10.18632/Oncotarget.4595  0.383
2015 Cesare AJ, Heaphy CM, O'Sullivan RJ. Visualization of Telomere Integrity and Function In Vitro and In Vivo Using Immunofluorescence Techniques. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. 73: 12.40.1-12.40.31. PMID 26132175 DOI: 10.1002/0471142956.Cy1240S73  0.403
2015 Heaphy CM, Asch-Kendrick R, Argani P, Meeker AK, Cimino-Mathews A. Telomere length alterations unique to invasive lobular carcinoma. Human Pathology. 46: 1197-203. PMID 26092192 DOI: 10.1016/J.Humpath.2015.05.001  0.451
2015 Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Van Blarigan EL, Mucci LA, Giovannucci EL, Stampfer MJ, Yoon G, Lee TK, Hicks JL, De Marzo AM, Meeker AK, Platz EA. Prediagnostic Obesity and Physical Inactivity Are Associated with Shorter Telomere Length in Prostate Stromal Cells. Cancer Prevention Research (Philadelphia, Pa.). 8: 737-42. PMID 25990087 DOI: 10.1158/1940-6207.Capr-15-0097  0.434
2015 Heaphy CM, Gaonkar G, Peskoe SB, Joshu CE, De Marzo AM, Lucia MS, Goodman PJ, Lippman SM, Thompson IM, Platz EA, Meeker AK. Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial. The Prostate. 75: 1160-6. PMID 25893825 DOI: 10.1002/Pros.22997  0.474
2015 Julin B, Shui I, Heaphy CM, Joshu CE, Meeker AK, Giovannucci E, De Vivo I, Platz EA. Circulating leukocyte telomere length and risk of overall and aggressive prostate cancer British Journal of Cancer. 112: 769-776. PMID 25562437 DOI: 10.1038/Bjc.2014.640  0.447
2015 Weber KA, Heaphy CM, Giovannucci E, Platz EA, Meeker AK. Abstract 832: Midlife racial differences In leukocyte telomere length and in associations between modifiable factors and telomere length Cancer Research. 75: 832-832. DOI: 10.1158/1538-7445.Am2015-832  0.355
2015 Shekhani MT, Barber J, Heaphy CM, Reis L, Guner G, Joshu C, Netto GJ, Meeker AK. Abstract 3783: High resolution telomere FISH analysis of testicular germ cell tumors reveals telomere anomalies specific to cancer subtypes and demonstrates telomere shortening as an early event in TGCT carcinogenesis Cancer Research. 75: 3783-3783. DOI: 10.1158/1538-7445.Am2015-3783  0.473
2014 Dogeas E, Karagkounis G, Heaphy CM, Hirose K, Pawlik TM, Wolfgang CL, Meeker A, Hruban RH, Cameron JL, Choti MA. Alternative lengthening of telomeres predicts site of origin in neuroendocrine tumor liver metastases. Journal of the American College of Surgeons. 218: 628-35. PMID 24655849 DOI: 10.1016/J.Jamcollsurg.2014.01.001  0.365
2014 Hurwitz LM, Heaphy CM, Joshu CE, Isaacs WB, Konishi Y, De Marzo AM, Isaacs SD, Wiley KE, Platz EA, Meeker AK. Telomere length as a risk factor for hereditary prostate cancer. The Prostate. 74: 359-64. PMID 24285042 DOI: 10.1002/Pros.22755  0.457
2013 Haffner MC, Mosbruger T, Esopi DM, Fedor H, Heaphy CM, Walker DA, Adejola N, Gürel M, Hicks J, Meeker AK, Halushka MK, Simons JW, Isaacs WB, De Marzo AM, Nelson WG, et al. Tracking the clonal origin of lethal prostate cancer. The Journal of Clinical Investigation. 123: 4918-22. PMID 24135135 DOI: 10.1172/Jci70354  0.495
2013 Heaphy CM, Schreck KC, Raabe E, Mao XG, An P, Chu Q, Poh W, Jiao Y, Rodriguez FJ, Odia Y, Meeker AK, Eberhart CG. A glioblastoma neurosphere line with alternative lengthening of telomeres. Acta Neuropathologica. 126: 607-8. PMID 24022427 DOI: 10.1007/S00401-013-1174-X  0.37
2013 Meeker A, Heaphy C. Gastroenteropancreatic endocrine tumors. Molecular and Cellular Endocrinology. 386: 101-20. PMID 23906538 DOI: 10.1016/J.Mce.2013.07.015  0.379
2013 Heaphy CM, Yoon GS, Peskoe SB, Joshu CE, Lee TK, Giovannucci E, Mucci LA, Kenfield SA, Stampfer MJ, Hicks JL, De Marzo AM, Platz EA, Meeker AK. Prostate cancer cell telomere length variability and stromal cell telomere length as prognostic markers for metastasis and death. Cancer Discovery. 3: 1130-41. PMID 23779129 DOI: 10.1158/2159-8290.Cd-13-0135  0.481
2013 Garcia-Rizo C, Fernandez-Egea E, Miller BJ, Oliveira C, Justicia A, Griffith JK, Heaphy CM, Bernardo M, Kirkpatrick B. Abnormal glucose tolerance, white blood cell count, and telomere length in newly diagnosed, antidepressant-naïve patients with depression. Brain, Behavior, and Immunity. 28: 49-53. PMID 23207109 DOI: 10.1016/J.Bbi.2012.11.009  0.603
2013 Nguyen DN, Heaphy CM, de Wilde RF, Orr BA, Odia Y, Eberhart CG, Meeker AK, Rodriguez FJ. Molecular and morphologic correlates of the alternative lengthening of telomeres phenotype in high-grade astrocytomas. Brain Pathology (Zurich, Switzerland). 23: 237-43. PMID 22928601 DOI: 10.1111/J.1750-3639.2012.00630.X  0.309
2013 Joshu CE, Peskoe SB, Heaphy CM, Kenfield SA, Mucci LA, Giovanucci E, Stampfer MJ, Yoon GS, Lee T, Hicks JL, Marzo AMD, Meeker AK, Platz EA. Abstract PR06: Prediagnostic obesity and inactivity are associated with shorter telomere length in prostate cancer-associated stromal cells Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Pr06  0.455
2013 Weber KA, Heaphy CM, Rohrmann S, Gonzalez B, Bienstock JL, Agurs-Collins T, Platz EA, Meeker AK. Abstract A63: Influence of in utero maternal and child factors on cord blood leukocyte telomere length and possible differences by race: Clues to the racial disparity in prostate cancer? Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-A63  0.39
2013 Heaphy CM, Haffner MC, Meeker AK. Abstract A06: A novel cell line model of the alternative lengthening of telomeres (ALT) telomere maintenance mechanism Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A06  0.456
2012 Butler KS, Hines WC, Heaphy CM, Griffith JK. Coordinate regulation between expression levels of telomere-binding proteins and telomere length in breast carcinomas. Cancer Medicine. 1: 165-75. PMID 23342266 DOI: 10.1002/Cam4.14  0.773
2012 Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, de Wilde RF, Rodriguez FJ, Rosemberg S, Oba-Shinjo SM, Nagahashi Marie SK, Bettegowda C, Agrawal N, Lipp E, Pirozzi C, Lopez G, et al. Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget. 3: 709-22. PMID 22869205 DOI: 10.18632/Oncotarget.588  0.324
2012 de Wilde RF, Heaphy CM, Maitra A, Meeker AK, Edil BH, Wolfgang CL, Ellison TA, Schulick RD, Molenaar IQ, Valk GD, Vriens MR, Borel Rinkes IH, Offerhaus GJ, Hruban RH, Matsukuma KE. Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 25: 1033-9. PMID 22575867 DOI: 10.1038/Modpathol.2012.53  0.396
2011 Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, Karnan S, Ota A, Wong HY, Konishi Y, Karakas B, Tahir K, Abukhdeir AM, Gustin JP, Cidado J, Wang GM, ... ... Heaphy CM, et al. Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 17773-8. PMID 21987798 DOI: 10.1073/Pnas.1110969108  0.44
2011 Heaphy CM, Subhawong AP, Hong SM, Goggins MG, Montgomery EA, Gabrielson E, Netto GJ, Epstein JI, Lotan TL, Westra WH, Shih IeM, Iacobuzio-Donahue CA, Maitra A, Li QK, Eberhart CG, et al. Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes. The American Journal of Pathology. 179: 1608-15. PMID 21888887 DOI: 10.1016/J.Ajpath.2011.06.018  0.537
2011 Wang Y, Meeker AK, Kowalski J, Tsai HL, Somervell H, Heaphy C, Sangenario LE, Prasad N, Westra WH, Zeiger MA, Umbricht CB. Telomere length is related to alternative splice patterns of telomerase in thyroid tumors. The American Journal of Pathology. 179: 1415-24. PMID 21763260 DOI: 10.1016/J.Ajpath.2011.05.056  0.395
2011 Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science (New York, N.Y.). 333: 425. PMID 21719641 DOI: 10.1126/Science.1207313  0.401
2011 Heaphy CM, Meeker AK. The potential utility of telomere-related markers for cancer diagnosis. Journal of Cellular and Molecular Medicine. 15: 1227-38. PMID 21352473 DOI: 10.1111/J.1582-4934.2011.01284.X  0.526
2011 Trujillo KA, Heaphy CM, Mai M, Vargas KM, Jones AC, Vo P, Butler KS, Joste NE, Bisoffi M, Griffith JK. Markers of fibrosis and epithelial to mesenchymal transition demonstrate field cancerization in histologically normal tissue adjacent to breast tumors. International Journal of Cancer. Journal International Du Cancer. 129: 1310-21. PMID 21105047 DOI: 10.1002/Ijc.25788  0.81
2011 Heaphy CM, Subhawong AP, Gross AL, Konishi Y, Kouprina N, Argani P, Visvanathan K, Meeker AK. Shorter telomeres in luminal B, HER-2 and triple-negative breast cancer subtypes. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 194-200. PMID 21057458 DOI: 10.1038/Modpathol.2010.198  0.462
2011 Hong SM, Heaphy CM, Shi C, Eo SH, Cho H, Meeker AK, Eshleman JR, Hruban RH, Goggins M. Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias Modern Pathology. 24: 256-266. PMID 20871595 DOI: 10.1038/Modpathol.2010.181  0.306
2010 Heaphy CM, Fleet TM, Treat EG, Lee SJ, Smith AY, Davis MS, Griffith JK, Fischer EG, Bisoffi M. Organ-wide telomeric status in diseased and disease-free prostatic tissues. The Prostate. 70: 1471-9. PMID 20687220 DOI: 10.1002/Pros.21182  0.689
2010 Treat EG, Heaphy CM, Massie LW, Bisoffi M, Smith AY, Davis MS, Griffith JK. Telomere DNA content in prostate biopsies predicts early rise in prostate-specific antigen after radical prostatectomy for prostate cancer. Urology. 75: 724-9. PMID 19615720 DOI: 10.1016/J.Urology.2009.04.032  0.688
2010 Heaphy CM, Haffner MC, Meeker AK. Abstract 3212: Development of a chemiluminescence-based single telomere length analysis (STELA) method Cancer Research. 70: 3212-3212. DOI: 10.1158/1538-7445.Am10-3212  0.438
2009 Subhawong AP, Heaphy CM, Argani P, Konishi Y, Kouprina N, Nassar H, Vang R, Meeker AK. The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 22: 1423-31. PMID 19734843 DOI: 10.1038/Modpathol.2009.125  0.494
2009 Heaphy CM, Griffith JK, Bisoffi M. Mammary field cancerization: molecular evidence and clinical importance. Breast Cancer Research and Treatment. 118: 229-39. PMID 19685287 DOI: 10.1007/S10549-009-0504-0  0.739
2009 Haaland CM, Heaphy CM, Butler KS, Fischer EG, Griffith JK, Bisoffi M. Differential gene expression in tumor adjacent histologically normal prostatic tissue indicates field cancerization. International Journal of Oncology. 35: 537-46. PMID 19639174 DOI: 10.3892/Ijo_00000365  0.79
2009 Fernandez-Egea E, Bernardo M, Heaphy CM, Griffith JK, Parellada E, Esmatjes E, Conget I, Nguyen L, George V, Stöppler H, Kirkpatrick B. Telomere length and pulse pressure in newly diagnosed, antipsychotic-naive patients with nonaffective psychosis. Schizophrenia Bulletin. 35: 437-42. PMID 19279086 DOI: 10.1093/Schbul/Sbn169  0.595
2009 Heaphy CM, Bisoffi M, Joste NE, Baumgartner KB, Baumgartner RN, Griffith JK. Genomic instability demonstrates similarity between DCIS and invasive carcinomas. Breast Cancer Research and Treatment. 117: 17-24. PMID 18785004 DOI: 10.1007/S10549-008-0165-4  0.719
2008 Heaphy CM, Treat EG, Fleet TM, Bisoffi M, Smith AY, Davis MS, Fischer EG, Griffith JK. FIELD EFFECT REVEALED BY 3D-MAPPING OF TELOMERE DNA CONTENT AND ALLELIC IMBALANCE IN WHOLE MOUNT PROSTATES Journal of Urology. 179: 725-725. DOI: 10.1016/S0022-5347(08)62114-X  0.672
2007 Heaphy CM, Bisoffi M, Griffith JK. Diagnostic significance of allelic imbalance in cancer. Expert Opinion On Medical Diagnostics. 1: 159-68. PMID 23489303 DOI: 10.1517/17530059.1.2.159  0.741
2007 Heaphy CM, Baumgartner KB, Bisoffi M, Baumgartner RN, Griffith JK. Telomere DNA content predicts breast cancer-free survival interval. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 7037-43. PMID 18056180 DOI: 10.1158/1078-0432.Ccr-07-0432  0.74
2007 Heaphy CM, Hines WC, Butler KS, Haaland CM, Heywood G, Fischer EG, Bisoffi M, Griffith JK. Assessment of the frequency of allelic imbalance in human tissue using a multiplex polymerase chain reaction system. The Journal of Molecular Diagnostics : Jmd. 9: 266-71. PMID 17384220 DOI: 10.2353/Jmoldx.2007.060115  0.742
2007 Liu Z, Wan G, Heaphy C, Bisoffi M, Griffith JK, Hu CA. A novel loss-of-function mutation in TP53 in an endometrial cancer cell line and uterine papillary serous carcinoma model. Molecular and Cellular Biochemistry. 297: 179-87. PMID 17119852 DOI: 10.1007/S11010-006-9345-X  0.68
2007 Treat EG, Heaphy CM, Bisoffi M, Griffith JK, Smith AY, Davis MS. 1432: Telomere DNA Content Predicts Biochemical Recurrence in a Retrospective Analysis of Prostate Cancer Biopsies Journal of Urology. 177: 472-473. DOI: 10.1016/S0022-5347(18)31633-1  0.713
2006 Bisoffi M, Heaphy CM, Griffith JK. Telomeres: prognostic markers for solid tumors. International Journal of Cancer. 119: 2255-60. PMID 16858685 DOI: 10.1002/Ijc.22120  0.733
2006 Fordyce CA, Heaphy CM, Bisoffi M, Wyaco JL, Joste NE, Mangalik A, Baumgartner KB, Baumgartner RN, Hunt WC, Griffith JK. Telomere content correlates with stage and prognosis in breast cancer. Breast Cancer Research and Treatment. 99: 193-202. PMID 16752076 DOI: 10.1007/S10549-006-9204-1  0.797
2006 Candia BJ, Hines WC, Heaphy CM, Griffith JK, Orlando RA. Protease nexin-1 expression is altered in human breast cancer. Cancer Cell International. 6: 16. PMID 16737540 DOI: 10.1186/1475-2867-6-16  0.793
2006 Heaphy CM, Bisoffi M, Fordyce CA, Haaland CM, Hines WC, Joste NE, Griffith JK. Telomere DNA content and allelic imbalance demonstrate field cancerization in histologically normal tissue adjacent to breast tumors. International Journal of Cancer. 119: 108-16. PMID 16450377 DOI: 10.1002/Ijc.21815  0.766
2005 Fordyce CA, Heaphy CM, Joste NE, Smith AY, Hunt WC, Griffith JK. Association between cancer-free survival and telomere DNA content in prostate tumors. The Journal of Urology. 173: 610-4. PMID 15643274 DOI: 10.1097/01.Ju.0000143195.49685.Ce  0.807
2002 Fordyce CA, Heaphy CM, Griffith JK. Chemiluminescent measurement of telomere DNA content in biopsies. Biotechniques. 33: 144-6, 148. PMID 12139239 DOI: 10.2144/02331Md02  0.796
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