Year |
Citation |
Score |
2024 |
Kalera K, Liu R, Lim J, Pathirage R, Swanson DH, Johnson UG, Stothard AI, Lee JJ, Poston AW, Woodruff PJ, Ronning DR, Eoh H, Swarts BM. Targeting Persistence through Inhibition of the Trehalose Catalytic Shift. Acs Infectious Diseases. PMID 38485491 DOI: 10.1021/acsinfecdis.4c00138 |
0.378 |
|
2023 |
Pathirage R, Favrot L, Petit C, Yamsek M, Singh S, Mallareddy JR, Rana S, Natarajan A, Ronning DR. CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Medicinal Chemistry. 14: 921-933. PMID 37252106 DOI: 10.1039/d3md00058c |
0.774 |
|
2023 |
Jayasinghe YP, Banco MT, Lindenberger JJ, Favrot L, Palčeková Z, Jackson M, Manabe S, Ronning DR. The mycothiol -transferase is divalent metal-dependent for mycothiol binding and transfer. Rsc Medicinal Chemistry. 14: 491-500. PMID 36970142 DOI: 10.1039/d2md00401a |
0.755 |
|
2023 |
Sharma S, Jayasinghe YP, Mishra NK, Orimoloye MO, Wong TY, Dalluge JJ, Ronning DR, Aldrich CC. Structural and Functional Characterization of Homoserine Transacetylase. Acs Infectious Diseases. PMID 36753622 DOI: 10.1021/acsinfecdis.2c00541 |
0.33 |
|
2022 |
Thanvi R, Jayasinghe TD, Kapil S, Obadawo BS, Ronning DR, Sucheck SJ. Synthesis of C/C-cyclitols and CN-aminocyclitols from maltose and X-ray crystal structure of GlgEI V279S in a complex with an amylostatin GXG-like derivative. Frontiers in Chemistry. 10: 950433. PMID 36157042 DOI: 10.3389/fchem.2022.950433 |
0.319 |
|
2021 |
Sudasinghe TD, Banco MT, Ronning DR. Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production. Scientific Reports. 11: 22240. PMID 34782676 DOI: 10.1038/s41598-021-01526-6 |
0.814 |
|
2021 |
Si A, Jayasinghe TD, Thanvi R, Ronning DR, Sucheck SJ. Stereoselective synthesis of a 4-⍺-glucoside of valienamine and its X-ray structure in complex with Streptomyces coelicolor GlgE1-V279S. Scientific Reports. 11: 13413. PMID 34183716 DOI: 10.1038/s41598-021-92554-9 |
0.352 |
|
2019 |
Vartak A, Goins C, de Moura VCN, Schreidah CM, Landgraf AD, Lin B, Du J, Jackson M, Ronning DR, Sucheck SJ. Biochemical and microbiological evaluation of -aryl urea derivatives against mycobacteria and mycobacterial hydrolases. Medchemcomm. 10: 1197-1204. PMID 31741730 DOI: 10.1039/C9Md00122K |
0.329 |
|
2018 |
Kapil S, Petit C, Drago VN, Ronning DR, Sucheck SJ. Synthesis and in vitro characterization of trehalose-based inhibitors of mycobacterial trehalose 6-phosphate phosphatases. Chembiochem : a European Journal of Chemical Biology. PMID 30402996 DOI: 10.1002/Cbic.201800551 |
0.366 |
|
2018 |
Goins CM, Sudasinghe TD, Liu X, Wang Y, O'Doherty GA, Ronning DR. Characterization of Tetrahydrolipstatin and Stereo-derivatives on the Inhibition of Essential Mycobacterium tuberculosis Lipid Esterases. Biochemistry. PMID 29601187 DOI: 10.1021/Acs.Biochem.8B00152 |
0.471 |
|
2018 |
Goins CM, Dajnowicz S, Smith MD, Parks JM, Ronning DR. Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into Antigen 85 catalysis. The Journal of Biological Chemistry. PMID 29352107 DOI: 10.1074/Jbc.Ra117.001681 |
0.481 |
|
2017 |
Banco MT, Mishra V, Greeley SC, Ronning DR. Direct Detection of Products from S-adenosylmethionine-Dependent Enzymes using a Competitive Fluorescence Polarization Assay. Analytical Chemistry. PMID 29275620 DOI: 10.1021/Acs.Analchem.7B03556 |
0.766 |
|
2017 |
Goins CM, Schreidah CM, Dajnowicz S, Ronning DR. Structural basis for lipid binding and mechanism of the Mycobacterium tuberculosis Rv3802 phospholipase. The Journal of Biological Chemistry. PMID 29247008 DOI: 10.1074/Jbc.Ra117.000240 |
0.498 |
|
2017 |
Veleti SK, Petit C, Ronning DR, Sucheck SJ. Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S. Organic & Biomolecular Chemistry. PMID 28422240 DOI: 10.1039/C7Ob00388A |
0.409 |
|
2017 |
Goins CM, Dajnowicz SJ, Thanna S, Sucheck SJ, Parks JM, Ronning DR. Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives. Acs Infectious Diseases. PMID 28285521 DOI: 10.1021/Acsinfecdis.7B00003 |
0.51 |
|
2017 |
Thanna S, Goins CM, Knudson SE, Slayden RA, Ronning DR, Sucheck SJ. Thermal and photoinduced copper-promoted C-Se bond formation: Synthesis of 2-alkyl-1,2-benzisoselenazol-3(2H)-ones and evaluation against Mycobacterium tuberculosis. The Journal of Organic Chemistry. PMID 28273423 DOI: 10.1021/Acs.Joc.7B00440 |
0.37 |
|
2016 |
Banco MT, Mishra V, Ostermann A, Schrader TE, Evans GB, Kovalevsky A, Ronning DR. Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states. Proceedings of the National Academy of Sciences of the United States of America. PMID 27856757 DOI: 10.1073/Pnas.1609718113 |
0.767 |
|
2016 |
Grzegorzewicz AE, De Sousa-d'Auria C, McNeil MR, Huc-Claustre E, Jones V, Petit C, Angala SK, Zemanová J, Wang Q, Belardinelli JM, Gao Q, Ishizaki Y, Mikušová K, Brennan PJ, Ronning DR, et al. Assembling of the Mycobacterium tuberculosis Cell Wall Core. The Journal of Biological Chemistry. PMID 27417139 DOI: 10.1074/Jbc.M116.739227 |
0.433 |
|
2016 |
Thanna S, Knudson SE, Grzegorzewicz A, Kapil S, Goins CM, Ronning DR, Jackson M, Slayden RA, Sucheck SJ. Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis. Organic & Biomolecular Chemistry. PMID 27251120 DOI: 10.1039/C6Ob00821F |
0.466 |
|
2015 |
Lindenberger JJ, Veleti SK, Wilson BN, Sucheck SJ, Ronning DR. Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors. Scientific Reports. 5: 12830. PMID 26245983 DOI: 10.1038/Srep12830 |
0.468 |
|
2015 |
Thanna S, Lindenberger JJ, Gaitonde VV, Ronning DR, Sucheck SJ. Synthesis of 2-deoxy-2,2-difluoro-α-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S. Organic & Biomolecular Chemistry. 13: 7542-50. PMID 26072729 DOI: 10.1039/C5Ob00867K |
0.422 |
|
2015 |
Grzegorzewicz AE, Eynard N, Quémard A, North EJ, Margolis A, Lindenberger JJ, Jones V, Korduláková J, Brennan PJ, Lee RE, Ronning DR, McNeil MR, Jackson M. Covalent modification of the Mycobacterium tuberculosis FAS-II dehydratase by Isoxyl and Thiacetazone. Acs Infectious Diseases. 1: 91-97. PMID 25897434 DOI: 10.1021/Id500032Q |
0.462 |
|
2015 |
Clark KD, Nacham O, Yu H, Li T, Yamsek MM, Ronning DR, Anderson JL. Extraction of DNA by magnetic ionic liquids: tunable solvents for rapid and selective DNA analysis. Analytical Chemistry. 87: 1552-9. PMID 25582771 DOI: 10.1021/Ac504260T |
0.687 |
|
2014 |
Anandan T, Han J, Baun H, Nyayapathy S, Brown JT, Dial RL, Moltalvo JA, Kim MS, Yang SH, Ronning DR, Husson RN, Suh J, Kang CM. Phosphorylation regulates mycobacterial proteasome. Journal of Microbiology (Seoul, Korea). 52: 743-54. PMID 25224505 DOI: 10.1007/S12275-014-4416-2 |
0.374 |
|
2014 |
Veleti SK, Lindenberger JJ, Thanna S, Ronning DR, Sucheck SJ. Synthesis of a poly-hydroxypyrolidine-based inhibitor of Mycobacterium tuberculosis GlgE. The Journal of Organic Chemistry. 79: 9444-50. PMID 25137149 DOI: 10.1021/Jo501481R |
0.419 |
|
2014 |
Favrot L, Lajiness DH, Ronning DR. Inactivation of the Mycobacterium tuberculosis antigen 85 complex by covalent, allosteric inhibitors. The Journal of Biological Chemistry. 289: 25031-40. PMID 25028518 DOI: 10.1074/Jbc.M114.582445 |
0.762 |
|
2014 |
Veleti SK, Lindenberger JJ, Ronning DR, Sucheck SJ. Synthesis of a C-phosphonate mimic of maltose-1-phosphate and inhibition studies on Mycobacterium tuberculosis GlgE. Bioorganic & Medicinal Chemistry. 22: 1404-11. PMID 24461562 DOI: 10.1016/J.Bmc.2013.12.058 |
0.467 |
|
2013 |
Favrot L, Grzegorzewicz AE, Lajiness DH, Marvin RK, Boucau J, Isailovic D, Jackson M, Ronning DR. Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen. Nature Communications. 4: 2748. PMID 24193546 DOI: 10.1038/Ncomms3748 |
0.745 |
|
2013 |
Pinault L, Han JS, Kang CM, Franco J, Ronning DR. Zafirlukast inhibits complexation of Lsr2 with DNA and growth of Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 57: 2134-40. PMID 23439641 DOI: 10.1128/Aac.02407-12 |
0.414 |
|
2013 |
Li T, Joshi MD, Ronning DR, Anderson JL. Ionic liquids as solvents for in situ dispersive liquid-liquid microextraction of DNA. Journal of Chromatography. A. 1272: 8-14. PMID 23261290 DOI: 10.1016/J.Chroma.2012.11.055 |
0.49 |
|
2012 |
Ibrahim DA, Boucau J, Lajiness DH, Veleti SK, Trabbic KR, Adams SS, Ronning DR, Sucheck SJ. Design, synthesis, and X-ray analysis of a glycoconjugate bound to Mycobacterium tuberculosis antigen 85C. Bioconjugate Chemistry. 23: 2403-16. PMID 23190459 DOI: 10.1021/Bc3004342 |
0.78 |
|
2012 |
Mishra V, Ronning DR. Crystal structures of the Helicobacter pylori MTAN enzyme reveal specific interactions between S-adenosylhomocysteine and the 5'-alkylthio binding subsite. Biochemistry. 51: 9763-72. PMID 23148563 DOI: 10.1021/Bi301221K |
0.612 |
|
2012 |
Favrot L, Ronning DR. Targeting the mycobacterial envelope for tuberculosis drug development. Expert Review of Anti-Infective Therapy. 10: 1023-36. PMID 23106277 DOI: 10.1586/Eri.12.91 |
0.756 |
|
2010 |
Ronning DR, Iacopelli NM, Mishra V. Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. Protein Science : a Publication of the Protein Society. 19: 2498-510. PMID 20954236 DOI: 10.1002/Pro.524 |
0.621 |
|
2010 |
Umesiri FE, Sanki AK, Boucau J, Ronning DR, Sucheck SJ. Recent advances toward the inhibition of mAG and LAM synthesis in Mycobacterium tuberculosis. Medicinal Research Reviews. 30: 290-326. PMID 20099253 DOI: 10.1002/Med.20190 |
0.721 |
|
2009 |
Sanki AK, Boucau J, Umesiri FE, Ronning DR, Sucheck SJ. Design, synthesis and biological evaluation of sugar-derived esters, alpha-ketoesters and alpha-ketoamides as inhibitors for Mycobacterium tuberculosis antigen 85C. Molecular Biosystems. 5: 945-56. PMID 19668859 DOI: 10.1039/B902284H |
0.684 |
|
2009 |
Sanki AK, Boucau J, Ronning DR, Sucheck SJ. Antigen 85C-mediated acyl-transfer between synthetic acyl donors and fragments of the arabinan. Glycoconjugate Journal. 26: 589-96. PMID 19052863 DOI: 10.1007/S10719-008-9211-Z |
0.657 |
|
2009 |
Boucau J, Sanki AK, Voss BJ, Sucheck SJ, Ronning DR. A coupled assay measuring Mycobacterium tuberculosis antigen 85C enzymatic activity. Analytical Biochemistry. 385: 120-7. PMID 18992216 DOI: 10.1016/J.Ab.2008.10.018 |
0.719 |
|
2008 |
Sanki AK, Boucau J, Srivastava P, Adams SS, Ronning DR, Sucheck SJ. Synthesis of methyl 5-S-alkyl-5-thio-D-arabinofuranosides and evaluation of their antimycobacterial activity. Bioorganic & Medicinal Chemistry. 16: 5672-82. PMID 18450455 DOI: 10.1016/J.Bmc.2008.03.062 |
0.719 |
|
2008 |
Barabas O, Ronning DR, Guynet C, Hickman AB, Ton-Hoang B, Chandler M, Dyda F. Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection. Cell. 132: 208-20. PMID 18243097 DOI: 10.1016/J.Cell.2007.12.029 |
0.409 |
|
2005 |
Ronning DR, Guynet C, Ton-Hoang B, Perez ZN, Ghirlando R, Chandler M, Dyda F. Active site sharing and subterminal hairpin recognition in a new class of DNA transposases. Molecular Cell. 20: 143-54. PMID 16209952 DOI: 10.1016/J.Molcel.2005.07.026 |
0.364 |
|
2005 |
Ton-Hoang B, Guynet C, Ronning DR, Cointin-Marty B, Dyda F, Chandler M. Transposition of ISHp608, member of an unusual family of bacterial insertion sequences. The Embo Journal. 24: 3325-38. PMID 16163392 DOI: 10.1038/Sj.Emboj.7600787 |
0.36 |
|
2005 |
Bradley CM, Ronning DR, Ghirlando R, Craigie R, Dyda F. Structural basis for DNA bridging by barrier-to-autointegration factor. Nature Structural & Molecular Biology. 12: 935-6. PMID 16155580 DOI: 10.1038/Nsmb989 |
0.355 |
|
2005 |
Gokulan K, Khare S, Ronning DR, Linthicum SD, Sacchettini JC, Rupp B. Cocrystal structures of NC6.8 Fab identify key interactions for high potency sweetener recognition: implications for the design of synthetic sweeteners. Biochemistry. 44: 9889-98. PMID 16026161 DOI: 10.1021/Bi050613U |
0.564 |
|
2004 |
Ronning DR, Li Y, Perez ZN, Ross PD, Hickman AB, Craig NL, Dyda F. The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA Embo Journal. 23: 2972-2981. PMID 15257292 DOI: 10.1038/Sj.Emboj.7600311 |
0.399 |
|
2004 |
Ronning DR, Vissa V, Besra GS, Belisle JT, Sacchettini JC. Mycobacterium tuberculosis antigen 85A and 85C structures confirm binding orientation and conserved substrate specificity. The Journal of Biological Chemistry. 279: 36771-7. PMID 15192106 DOI: 10.1074/Jbc.M400811200 |
0.611 |
|
2004 |
Hickman AB, Ronning DR, Perez ZN, Kotin RM, Dyda F. The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces. Molecular Cell. 13: 403-14. PMID 14967147 DOI: 10.1016/S1097-2765(04)00023-1 |
0.376 |
|
2003 |
Sharma V, Arockiasamy A, Ronning DR, Savva CG, Holzenburg A, Braunstein M, Jacobs WR, Sacchettini JC. Crystal structure of Mycobacterium tuberculosis SecA, a preprotein translocating ATPase. Proceedings of the National Academy of Sciences of the United States of America. 100: 2243-8. PMID 12606717 DOI: 10.1073/Pnas.0538077100 |
0.538 |
|
2002 |
Riley-Lovingshimer MR, Ronning DR, Sacchettini JC, Reinhart GD. Reversible ligand-induced dissociation of a tryptophan-shift mutant of phosphofructokinase from Bacillus stearothermophilus. Biochemistry. 41: 12967-74. PMID 12390023 DOI: 10.1021/Bi0263412 |
0.59 |
|
2002 |
Hickman AB, Ronning DR, Kotin RM, Dyda F. Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adeno-associated virus Rep. Molecular Cell. 10: 327-37. PMID 12191478 DOI: 10.1016/S1097-2765(02)00592-0 |
0.349 |
|
2000 |
Sacchettini JC, Ronning DR. The mycobacterial antigens 85 complex--from structure to function: response. Trends in Microbiology. 8: 441. PMID 11203233 DOI: 10.1016/S0966-842X(00)01843-6 |
0.591 |
|
2000 |
Ronning DR, Klabunde T, Besra GS, Vissa VD, Belisle JT, Sacchettini JC. Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines. Nature Structural Biology. 7: 141-6. PMID 10655617 DOI: 10.1038/72413 |
0.628 |
|
2000 |
O'Hagan RC, Schreiber-Agus N, Chen K, David G, Engelman JA, Schwab R, Alland L, Thomson C, Ronning DR, Sacchettini JC, Meltzer P, DePinho RA. Gene-target recognition among members of the myc superfamily and implications for oncogenesis. Nature Genetics. 24: 113-9. PMID 10655054 DOI: 10.1038/72761 |
0.499 |
|
1999 |
O'Hagan R, Schreiber-Agus N, Engelman JA, Schwab R, Alland L, Thompson C, Ronning DR, Sacchettini JC, Meltzer P, DePinho RA. Identification of differentially regulated gene targets in the Myc and Mad family proteins Nature Genetics. 23: 66-66. DOI: 10.1038/14378 |
0.468 |
|
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