| Year |
Citation |
Score |
| 2020 |
Pang L, Shah H, Wang H, Shu D, Qian SY, Sathish V. EpCAM-Targeted 3WJ RNA Nanoparticle Harboring Delta-5-Desaturase siRNA Inhibited Lung Tumor Formation via DGLA Peroxidation. Molecular Therapy. Nucleic Acids. 22: 222-235. PMID 33230429 DOI: 10.1016/J.Omtn.2020.08.024 |
0.339 |
|
| 2020 |
Shah H, Pang L, Wang H, Shu D, Qian SY, Sathish V. Growth inhibitory and anti-metastatic activity of epithelial cell adhesion molecule targeted three-way junctional Delta-5-Desaturase siRNA nanoparticle for breast cancer therapy. Nanomedicine : Nanotechnology, Biology, and Medicine. 102298. PMID 32931930 DOI: 10.1016/J.Nano.2020.102298 |
0.371 |
|
| 2020 |
Shah H, Pang L, Qian S, Zhao P, Sathish V. Development of a Novel ω‐6 Polyunsaturated Fatty Acid Based Treatment Strategy for Non‐Melanoma Skin Cancer by Inhibiting Delta‐5‐Desaturase The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09432 |
0.331 |
|
| 2019 |
Wood I, Trostchansky A, Xu Y, Qian S, Radi R, Rubbo H. Free radical-dependent inhibition of prostaglandin endoperoxide H Synthase-2 by nitro-arachidonic acid. Free Radical Biology & Medicine. PMID 30922958 DOI: 10.1016/J.Freeradbiomed.2019.03.022 |
0.365 |
|
| 2019 |
Gao Y, Zhou S, Pang L, Yang J, Li HJ, Huo X, Qian SY. Celastrol suppresses nitric oxide synthases and the angiogenesis pathway in colorectal cancer. Free Radical Research. 1-11. PMID 30773944 DOI: 10.1080/10715762.2019.1575512 |
0.367 |
|
| 2018 |
Gao Y, Zhou S, Xu Y, Sheng S, Qian SY, Huo X. Nitric oxide synthase inhibitors 1400W and L-NIO inhibit angiogenesis pathway of colorectal cancer. Nitric Oxide : Biology and Chemistry. PMID 30590117 DOI: 10.1016/J.Niox.2018.12.008 |
0.342 |
|
| 2018 |
Xu Y, Pang L, Wang H, Xu C, Shah H, Guo P, Shu D, Qian SY. Specific delivery of delta-5-desaturase siRNA via RNA nanoparticles supplemented with dihomo-γ-linolenic acid for colon cancer suppression. Redox Biology. 21: 101085. PMID 30584980 DOI: 10.1016/J.Redox.2018.101085 |
0.351 |
|
| 2018 |
Xu Y, Yang X, Gao D, Yang L, Miskimins K, Qian SY. Dihomo-γ-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase. Bmc Cancer. 18: 1268. PMID 30567534 DOI: 10.1186/S12885-018-5185-9 |
0.37 |
|
| 2018 |
Yang X, Xu Y, Gao D, Yang L, Qian SY. Dihomo-γ-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA. Redox Biology. 20: 236-246. PMID 30384258 DOI: 10.1016/J.Redox.2018.10.001 |
0.366 |
|
| 2018 |
Xu Y, Yang X, Wang T, Yang L, He YY, Miskimins K, Qian SY. Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism. Bmc Cancer. 18: 330. PMID 29587668 DOI: 10.1186/S12885-018-4250-8 |
0.39 |
|
| 2017 |
Qi J, Sun LQ, Qian SY, Yu BY. A novel multi-hyphenated analytical method to simultaneously determine xanthine oxidase inhibitors and superoxide anion scavengers in natural products. Analytica Chimica Acta. 984: 124-133. PMID 28843555 DOI: 10.1016/J.Aca.2017.07.023 |
0.334 |
|
| 2017 |
Yang X, Xu Y, Wang T, Shu D, Guo P, Miskimins K, Qian SY. Erratum to "Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells" [Redox Biol. 11 (2017) 653-662]. Redox Biology. PMID 28410935 DOI: 10.1016/J.Redox.2017.03.021 |
0.345 |
|
| 2017 |
Yang X, Xu Y, Wang T, Shu D, Guo P, Miskimins K, Qian SY. Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells. Redox Biology. 11: 653-662. PMID 28157665 DOI: 10.1016/J.Redox.2017.01.016 |
0.377 |
|
| 2017 |
Xu Y, Yang X, Pang L, Shah H, Qian S. A Paradigm Shifting Concept: Inhibiting Tumor Growth and Metastasis Potential by Exploiting Overexpressed COX-2 in Cancer Cells along with shRNA-Knockdown of Delta-5-Desaturase and DGLA Supplementation Free Radical Biology and Medicine. 112: 105. DOI: 10.1016/J.Freeradbiomed.2017.10.159 |
0.368 |
|
| 2016 |
Zhao Z, Reinstatler L, Klaassen Z, Xu Y, Yang X, Madi R, Terris MK, Qian SY, Kelavkar U, Moses KA. The Association of Fatty Acid Levels and Gleason Grade among Men Undergoing Radical Prostatectomy. Plos One. 11: e0166594. PMID 27880795 DOI: 10.1371/Journal.Pone.0166594 |
0.35 |
|
| 2016 |
Yang X, Xu Y, Brooks A, Guo B, Miskimins KW, Qian SY. Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs. Free Radical Biology & Medicine. PMID 27368132 DOI: 10.1016/J.Freeradbiomed.2016.06.028 |
0.422 |
|
| 2016 |
Xu Y, Yang X, Zhao P, Yang Z, Yan C, Guo B, Qian SY. Knockdown of delta-5-desaturase promotes the anti-cancer activity of dihomo-γ-linolenic acid and enhances the efficacy of chemotherapy in colon cancer cells expressing COX-2. Free Radical Biology & Medicine. PMID 27101738 DOI: 10.1016/J.Freeradbiomed.2016.04.016 |
0.43 |
|
| 2016 |
Stebbins NB, Howarda LR, Prior RL, Brownmiller C, Liyanage R, Lay JO, Yang X, Qian SY. Ascorbic acid-catalyzed degradation of cyanidin-3-O-β-glucoside: Proposed mechanism and identification of a novel hydroxylated product Journal of Berry Research. 6: 175-187. DOI: 10.3233/Jbr-160132 |
0.32 |
|
| 2016 |
Yang X, Xu Y, Miskimins KW, Qian SY. Knocking Down Delta-5 Desaturase and Exploiting High Expression Level of COX-2 to Inhibit Cancer Migration and Invasion Free Radical Biology and Medicine. 100: S133. DOI: 10.1016/J.Freeradbiomed.2016.10.351 |
0.374 |
|
| 2016 |
Xu Y, Yang X, Gao D, Miskimins K, Qian S. Suppressing Colon Cancer Growth in Xenograft Tumors via Knocking Down Delta-5-Desaturase and Exploiting High COX-2 Expression Levels in Cancer Free Radical Biology and Medicine. 100: S133. DOI: 10.1016/J.Freeradbiomed.2016.10.350 |
0.356 |
|
| 2015 |
Alwarsh S, Xu Y, Qian SY, McIntosh MC. Radical [1,3] Rearrangements of Breslow Intermediates. Angewandte Chemie (International Ed. in English). PMID 26553753 DOI: 10.1002/Anie.201508368 |
0.312 |
|
| 2015 |
Brigandi SA, Shao H, Qian SY, Shen Y, Wu BL, Kang JX. Autistic children exhibit decreased levels of essential Fatty acids in red blood cells. International Journal of Molecular Sciences. 16: 10061-76. PMID 25946342 DOI: 10.3390/Ijms160510061 |
0.309 |
|
| 2015 |
Xu Y, Yang X, Qiu L, Qian S. Delta-5-Desaturase Knockdown Promoted ra-6's Anti-Cancer Effects from the Free Radical Byproducts Generated in COX-Catalyzed Dihomo-y-Linolenic Acid Peroxidation Free Radical Biology and Medicine. 87: S74-S75. DOI: 10.1016/J.Freeradbiomed.2015.10.196 |
0.371 |
|
| 2014 |
Xu Y, Qi J, Yang X, Wu E, Qian SY. Free radical derivatives formed from cyclooxygenase-catalyzed dihomo-γ-linolenic acid peroxidation can attenuate colon cancer cell growth and enhance 5-fluorouracil's cytotoxicity. Redox Biology. 2: 610-8. PMID 25114837 DOI: 10.1016/J.Redox.2014.01.022 |
0.448 |
|
| 2014 |
Xu Y, Qian SY. Anti-cancer activities of ω-6 polyunsaturated fatty acids. Biomedical Journal. 37: 112-9. PMID 24923568 DOI: 10.4103/2319-4170.131378 |
0.396 |
|
| 2014 |
Xu Y, Yang X, Qian S. A New Insight into COX Biology: Elicit the Free Radical-Mediated Anti-Cancer Activities of Dihomo-Gamma-Linolenic Acid by Delta-5 Desaturase Regulation Free Radical Biology and Medicine. 76: S136. DOI: 10.1016/J.Freeradbiomed.2014.10.225 |
0.395 |
|
| 2013 |
Pender-Cudlip MC, Krag KJ, Martini D, Yu J, Guidi A, Skinner SS, Zhang Y, Qu X, He C, Xu Y, Qian SY, Kang JX. Delta-6-desaturase activity and arachidonic acid synthesis are increased in human breast cancer tissue. Cancer Science. 104: 760-4. PMID 23414387 DOI: 10.1111/Cas.12129 |
0.31 |
|
| 2013 |
Gu Y, Xu Y, Law B, Qian SY. The first characterization of free radicals formed from cellular COX-catalyzed peroxidation. Free Radical Biology & Medicine. 57: 49-60. PMID 23261941 DOI: 10.1016/J.Freeradbiomed.2012.12.004 |
0.436 |
|
| 2013 |
Xu Y, Yang X, Qi J, Qian S. Elicit the Anti-Cancer Activities of Dihomo-Gamma-Linolenic Acid by Delta-5 Desaturase Regulation: a Mechanism Study on Free Radical Lipid Peroxidation Free Radical Biology and Medicine. 65: S26. DOI: 10.1016/J.Freeradbiomed.2013.10.446 |
0.414 |
|
| 2012 |
Xu Y, Gu Y, Qian SY. An advanced Electron Spin Resonance (ESR) spin-trapping and LC/(ESR)/MS technique for the study of lipid peroxidation. International Journal of Molecular Sciences. 13: 14648-66. PMID 23203086 DOI: 10.3390/Ijms131114648 |
0.405 |
|
| 2012 |
He C, Qu X, Wan J, Rong R, Huang L, Cai C, Zhou K, Gu Y, Qian SY, Kang JX. Inhibiting delta-6 desaturase activity suppresses tumor growth in mice. Plos One. 7: e47567. PMID 23112819 DOI: 10.1371/Journal.Pone.0047567 |
0.318 |
|
| 2012 |
Gu Y, Xu Y, Qian S. The Potential Inhibitory Effect of DGLA on Colon Cancer Cell Growth Via Free Radical Metabolites in COX-Catalyzed Peroxidation Free Radical Biology and Medicine. 53: S22. DOI: 10.1016/J.Freeradbiomed.2012.10.051 |
0.402 |
|
| 2011 |
Purwaha P, Gu Y, Kelavkar U, Kang JX, Law B, Wu E, Qian SY. LC/ESR/MS study of pH-dependent radical generation from 15-LOX-catalyzed DPA peroxidation. Free Radical Biology & Medicine. 51: 1461-70. PMID 21807091 DOI: 10.1016/J.Freeradbiomed.2011.07.001 |
0.423 |
|
| 2011 |
Wang F, Bhat K, Doucette M, Zhou S, Gu Y, Law B, Liu X, Wong ET, Kang JX, Hsieh TC, Qian SY, Wu E. Docosahexaenoic acid (DHA) sensitizes brain tumor cells to etoposide-induced apoptosis. Current Molecular Medicine. 11: 503-11. PMID 21663587 DOI: 10.2174/156652411796268740 |
0.309 |
|
| 2011 |
Xiao Y, Gu Y, Purwaha P, Ni K, Law B, Mallik S, Qian SY. Characterization of free radicals formed from COX-catalyzed DGLA peroxidation. Free Radical Biology & Medicine. 50: 1163-70. PMID 21310230 DOI: 10.1016/J.Freeradbiomed.2011.02.001 |
0.375 |
|
| 2011 |
Qian SY, Gu AY, Xu Y. Different Free Radical Mechanisms in COX-Catalyzed Peroxidation of Arachidonic Acid Vs. Dihomo-Gamma-Linolenic Acid May Correspond To Their Contrasting Bioactivity Free Radical Biology and Medicine. 51: S57-S58. DOI: 10.1016/J.Freeradbiomed.2011.10.149 |
0.353 |
|
| 2010 |
Qian S, Gu Y, Xiao Y, Mallik S. Characterization of Carbon-Centered Radicals Formed from COX-Catalyzed Dihomo-Gamma-Linolenic Acid Peroxidation Free Radical Biology and Medicine. 49: S214. DOI: 10.1016/J.Freeradbiomed.2010.10.624 |
0.344 |
|
| 2010 |
Gu Y, Perwaha P, Qian SY. pH-Dependent Radical Metabolite Pattern of 15-Lipoxygenase-Catalyzed Lipid Peroxidation: HPLC/ESR/MS Study Free Radical Biology and Medicine. 49: S210. DOI: 10.1016/J.Freeradbiomed.2010.10.610 |
0.309 |
|
| 2009 |
Yu Q, Purwaha P, Ni K, Sun C, Mallik S, Qian SY. Characterization of novel radicals from COX-catalyzed arachidonic acid peroxidation. Free Radical Biology & Medicine. 47: 568-76. PMID 19482075 DOI: 10.1016/J.Freeradbiomed.2009.05.023 |
0.41 |
|
| 2009 |
Shan Z, Yu Q, Purwaha P, Guo B, Qian SY. A combination study of spin-trapping, LC/ESR and LC/MS on carbon-centred radicals formed from lipoxygenase-catalysed peroxidation of eicosapentaenoic acid. Free Radical Research. 43: 13-27. PMID 19085251 DOI: 10.1080/10715760802567606 |
0.413 |
|
| 2008 |
Liu J, Qian SY, Guo Q, Jiang J, Waalkes MP, Mason RP, Kadiiska MB. Cadmium generates reactive oxygen- and carbon-centered radical species in rats: insights from in vivo spin-trapping studies. Free Radical Biology & Medicine. 45: 475-81. PMID 18501199 DOI: 10.1016/J.Freeradbiomed.2008.04.041 |
0.343 |
|
| 2008 |
Yu Q, Shan Z, Ni K, Qian SY. LC/ESR/MS study of spin trapped carbon-centred radicals formed from in vitro lipoxygenase-catalysed peroxidation of gamma-linolenic acid. Free Radical Research. 42: 442-55. PMID 18484409 DOI: 10.1080/10715760802085344 |
0.41 |
|
| 2004 |
Guo Q, Gao G, Qian SY, Mason RP. Novel identification of a sulfur-centered, radical-derived 5,5-dimethyl-1-pyrroline N-oxide nitrone adduct formed from the oxidation of DTT by LC/ELISA, LC/electrospray ionization-MS, and LC/tandem MS. Chemical Research in Toxicology. 17: 1481-90. PMID 15540946 DOI: 10.1021/Tx049837O |
0.32 |
|
| 2003 |
Towner RA, Qian SY, Kadiiska MB, Mason RP. In vivo identification of aflatoxin-induced free radicals in rat bile. Free Radical Biology & Medicine. 35: 1330-40. PMID 14607532 DOI: 10.1016/J.Freeradbiomed.2003.08.002 |
0.362 |
|
| 2003 |
Guo Q, Qian SY, Mason RP. Separation and identification of DMPO adducts of oxygen-centered radicals formed from organic hydroperoxides by HPLC-ESR, ESI-MS and MS/MS. Journal of the American Society For Mass Spectrometry. 14: 862-71. PMID 12892910 DOI: 10.1016/S1044-0305(03)00336-2 |
0.33 |
|
| 2003 |
Qian SY, Guo Q, Mason RP. Identification of spin trapped carbon-centered radicals in soybean lipoxygenase-dependent peroxidations of omega-3 polyunsaturated fatty acids by LC/ESR, LC/MS, and tandem MS. Free Radical Biology & Medicine. 35: 33-44. PMID 12826254 DOI: 10.1016/S0891-5849(03)00217-X |
0.351 |
|
| 2003 |
Qian SY, Yue GH, Tomer KB, Mason RP. Identification of all classes of spin-trapped carbon-centered radicals in soybean lipoxygenase-dependent lipid peroxidations of omega-6 polyunsaturated fatty acids via LC/ESR, LC/MS, and tandem MS. Free Radical Biology & Medicine. 34: 1017-28. PMID 12684086 DOI: 10.1016/S0891-5849(03)00031-5 |
0.362 |
|
| 2002 |
Qian SY, Chen YR, Deterding LJ, Fann YC, Chignell CF, Tomer KB, Mason RP. Identification of protein-derived tyrosyl radical in the reaction of cytochrome c and hydrogen peroxide: characterization by ESR spin-trapping, HPLC and MS. The Biochemical Journal. 363: 281-8. PMID 11931655 DOI: 10.1042/0264-6021:3630281 |
0.303 |
|
| 2002 |
Guo Q, Corbett JT, Yue G, Fann YC, Qian SY, Tomer KB, Mason RP. Electron spin resonance investigation of semiquinone radicals formed from the reaction of ubiquinone 0 with human oxyhemoglobin. The Journal of Biological Chemistry. 277: 6104-10. PMID 11748217 DOI: 10.1074/Jbc.M106395200 |
0.32 |
|
| 2001 |
Wang HP, Qian SY, Schafer FQ, Domann FE, Oberley LW, Buettner GR. Phospholipid hydroperoxide glutathione peroxidase protects against singlet oxygen-induced cell damage of photodynamic therapy. Free Radical Biology & Medicine. 30: 825-35. PMID 11295525 DOI: 10.1016/S0891-5849(01)00469-5 |
0.54 |
|
| 2000 |
Qian SY, Wang HP, Schafer FQ, Buettner GR. EPR detection of lipid-derived free radicals from PUFA, LDL, and cell oxidations. Free Radical Biology & Medicine. 29: 568-79. PMID 11025200 DOI: 10.1016/S0891-5849(00)00407-X |
0.522 |
|
| 2000 |
Schafer FQ, Qian SY, Buettner GR. Iron and free radical oxidations in cell membranes. Cellular and Molecular Biology (Noisy-Le-Grand, France). 46: 657-62. PMID 10872752 |
0.474 |
|
| 1999 |
Qian SY, Buettner GR. Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations: an electron paramagnetic resonance spin trapping study. Free Radical Biology & Medicine. 26: 1447-56. PMID 10401608 DOI: 10.1016/S0891-5849(99)00002-7 |
0.506 |
|
| 1999 |
Wang H, Qian SY, Schafer F, Oberley LW, Buettner GR. Phospholipid hydroperoxide glutathione peroxidase (PhGPx) uniquely protects cell membranes from photo-oxidation Free Radical Biology and Medicine. 27: S46. DOI: 10.1016/S0891-5849(99)90652-4 |
0.496 |
|
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