| Year |
Citation |
Score |
| 2014 |
Kok BP, Skene-Arnold TD, Ling J, Benesch MG, Dewald J, Harris TE, Holmes CF, Brindley DN. Conserved residues in the N terminus of lipin-1 are required for binding to protein phosphatase-1c, nuclear translocation, and phosphatidate phosphatase activity. The Journal of Biological Chemistry. 289: 10876-86. PMID 24558042 DOI: 10.1074/Jbc.M114.552612 |
0.307 |
|
| 2013 |
Shopik MJ, Li L, Luu HA, Obeidat M, Holmes CF, Ballermann BJ. Multi-directional function of the protein phosphatase 1 regulatory subunit TIMAP. Biochemical and Biophysical Research Communications. 435: 567-73. PMID 23685145 DOI: 10.1016/j.bbrc.2013.05.012 |
0.439 |
|
| 2013 |
Skene-Arnold TD, Luu HA, Uhrig RG, De Wever V, Nimick M, Maynes J, Fong A, James MN, Trinkle-Mulcahy L, Moorhead GB, Holmes CF. Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins. The Biochemical Journal. 449: 649-59. PMID 23088536 DOI: 10.1042/Bj20120506 |
0.599 |
|
| 2012 |
Ceholski DK, Trieber CA, Holmes CF, Young HS. Lethal, hereditary mutants of phospholamban elude phosphorylation by protein kinase A. The Journal of Biological Chemistry. 287: 26596-605. PMID 22707725 DOI: 10.1074/Jbc.M112.382713 |
0.409 |
|
| 2009 |
Freschauf GK, Karimi-Busheri F, Ulaczyk-Lesanko A, Mereniuk TR, Ahrens A, Koshy JM, Rasouli-Nia A, Pasarj P, Holmes CF, Rininsland F, Hall DG, Weinfeld M. Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase. Cancer Research. 69: 7739-46. PMID 19773431 DOI: 10.1158/0008-5472.Can-09-1805 |
0.32 |
|
| 2007 |
Carr G, Raszek M, Van Soest R, Matainaho T, Shopik M, Holmes CF, Andersen RJ. Protein phosphatase inhibitors isolated from Spongia irregularis collected in Papua New Guinea. Journal of Natural Products. 70: 1812-5. PMID 17979246 DOI: 10.1021/Np0702887 |
0.487 |
|
| 2007 |
Li L, Kozlowski K, Wegner B, Rashid T, Yeung T, Holmes C, Ballermann BJ. Phosphorylation of TIMAP by glycogen synthase kinase-3beta activates its associated protein phosphatase 1. The Journal of Biological Chemistry. 282: 25960-9. PMID 17609201 DOI: 10.1074/jbc.M703532200 |
0.35 |
|
| 2006 |
Maynes JT, Luu HA, Cherney MM, Andersen RJ, Williams D, Holmes CF, James MN. Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins. Journal of Molecular Biology. 356: 111-20. PMID 16343532 DOI: 10.1016/J.Jmb.2005.11.019 |
0.398 |
|
| 2005 |
Misik AJ, Perreault K, Holmes CF, Fliegel L. Protein phosphatase regulation of Na+/H+ exchanger isoform I. Biochemistry. 44: 5842-52. PMID 15823043 DOI: 10.1021/bi047659s |
0.357 |
|
| 2005 |
Plummer G, Perreault KR, Holmes CF, Posse De Chaves EI. Activation of serine/threonine protein phosphatase-1 is required for ceramide-induced survival of sympathetic neurons. The Biochemical Journal. 385: 685-93. PMID 15361069 DOI: 10.1042/BJ20040929 |
0.317 |
|
| 2002 |
Holmes CF, Maynes JT, Perreault KR, Dawson JF, James MN. Molecular enzymology underlying regulation of protein phosphatase-1 by natural toxins. Current Medicinal Chemistry. 9: 1981-9. PMID 12369866 DOI: 10.2174/0929867023368827 |
0.452 |
|
| 2001 |
Maynes JT, Bateman KS, Cherney MM, Das AK, Luu HA, Holmes CF, James MN. Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1. The Journal of Biological Chemistry. 276: 44078-82. PMID 11535607 DOI: 10.1074/Jbc.M107656200 |
0.409 |
|
| 2000 |
Dawson JF, Luu HA, Bagu JR, Holmes CF. Mutation of the toxin binding site of PP-1c: comparison with PP-2B. Biochemical and Biophysical Research Communications. 270: 543-9. PMID 10753661 DOI: 10.1006/bbrc.2000.2459 |
0.322 |
|
| 2000 |
McCready TL, Islam BF, Schmitz FJ, Luu HA, Dawson JF, Holmes CF. Inhibition of protein phosphatase-1 by clavosines A and B. Novel members of the calyculin family of toxins. The Journal of Biological Chemistry. 275: 4192-8. PMID 10660582 DOI: 10.1074/jbc.275.6.4192 |
0.324 |
|
| 1999 |
Dawson JF, Holmes CF. Identification of sds21 in fission yeast in an inhibitor-resistant high molecular mass protein phosphatase-1 complex. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 77: 551-8. PMID 10668632 |
0.437 |
|
| 1999 |
Dawson JF, Holmes CF. Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins. Frontiers in Bioscience : a Journal and Virtual Library. 4: D646-58. PMID 10502549 |
0.48 |
|
| 1997 |
Bagu JR, Sykes BD, Craig MM, Holmes CF. A molecular basis for different interactions of marine toxins with protein phosphatase-1. Molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A. The Journal of Biological Chemistry. 272: 5087-97. PMID 9030574 DOI: 10.1074/jbc.272.8.5087 |
0.365 |
|
| 1996 |
Craig M, Luu HA, McCready TL, Williams D, Andersen RJ, Holmes CF. Molecular mechanisms underlying he interaction of motuporin and microcystins with type-1 and type-2A protein phosphatases. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 74: 569-78. PMID 8960363 DOI: 10.1139/O96-061 |
0.413 |
|
| 1996 |
Dawson JF, Wang KH, Holmes CF. Identification and characterization of cAMP-dependent protein kinase and its possible direct interactions with protein phosphatase-1 in marine dinoflagellates. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 74: 559-67. PMID 8960362 |
0.436 |
|
| 1995 |
Bagu JR, Sönnichsen FD, Williams D, Andersen RJ, Sykes BD, Holmes CF. Comparison of the solution structures of microcystin-LR and motuporin. Nature Structural Biology. 2: 114-6. PMID 7749913 DOI: 10.1038/Nsb0295-114 |
0.347 |
|
| 1994 |
Dawson JF, Boland MP, Holmes CF. A capillary electrophoresis-based assay for protein kinases and protein phosphatases using peptide substrates. Analytical Biochemistry. 220: 340-5. PMID 7978276 DOI: 10.1006/abio.1994.1347 |
0.445 |
|
| 1993 |
Milner RE, Busaan JL, Holmes CF, Wang JH, Michalak M. Phosphorylation of dystrophin. The carboxyl-terminal region of dystrophin is a substrate for in vitro phosphorylation by p34cdc2 protein kinase. The Journal of Biological Chemistry. 268: 21901-5. PMID 8408045 |
0.463 |
|
| 1993 |
Luu HA, Chen DZ, Magoon J, Worms J, Smith J, Holmes CF. Quantification of diarrhetic shellfish toxins and identification of novel protein phosphatase inhibitors in marine phytoplankton and mussels. Toxicon : Official Journal of the International Society On Toxinology. 31: 75-83. PMID 8383366 |
0.435 |
|
| 1993 |
Boland MP, Taylor MF, Holmes CF. Identification and characterisation of a type-1 protein phosphatase from the okadaic acid-producing marine dinoflagellate Prorocentrum lima. Febs Letters. 334: 13-7. PMID 8224216 |
0.43 |
|
| 1993 |
Craig M, McCready TL, Luu HA, Smillie MA, Dubord P, Holmes CF. Identification and characterization of hydrophobic microcystins in Canadian freshwater cyanobacteria. Toxicon : Official Journal of the International Society On Toxinology. 31: 1541-9. PMID 8146867 |
0.372 |
|
| 1992 |
Thibault P, Faubert D, Karunanithy S, Boyd RK, Holmes CF. Isolation, mass spectrometric characterization, and protein phosphatase inhibition properties of cyclic peptide analogues of gramicidin-S from Bacillus brevis (Nagano strain). Biological Mass Spectrometry. 21: 367-79. PMID 1381222 DOI: 10.1002/Bms.1200210802 |
0.309 |
|
| 1991 |
Holmes CF. Liquid chromatography-linked protein phosphatase bioassay; a highly sensitive marine bioscreen for okadaic acid and related diarrhetic shellfish toxins. Toxicon : Official Journal of the International Society On Toxinology. 29: 469-77. PMID 1650505 DOI: 10.1016/0041-0101(91)90021-I |
0.317 |
|
| 1990 |
Cohen P, Holmes CF, Tsukitani Y. Okadaic acid: a new probe for the study of cellular regulation. Trends in Biochemical Sciences. 15: 98-102. PMID 2158158 DOI: 10.1016/0968-0004(90)90192-E |
0.504 |
|
| 1988 |
Cohen P, Foulkes JG, Holmes CF, Nimmo GA, Tonks NK. Protein phosphatase inhibitor-1 and inhibitor-2 from rabbit skeletal muscle. Methods in Enzymology. 159: 427-37. PMID 2842607 DOI: 10.1016/0076-6879(88)59042-0 |
0.603 |
|
| 1988 |
Poulter L, Ang SG, Gibson BW, Williams DH, Holmes CF, Caudwell FB, Pitcher J, Cohen P. Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast-atom-bombardment mass spectrometry. European Journal of Biochemistry. 175: 497-510. PMID 2842154 DOI: 10.1111/J.1432-1033.1988.Tb14222.X |
0.563 |
|
| 1987 |
Holmes CF. A new method for the selective isolation of phosphoserine-containing peptides. Febs Letters. 215: 21-4. PMID 3106092 DOI: 10.1016/0014-5793(87)80106-0 |
0.304 |
|
| 1987 |
Holmes CF, Tonks NK, Major H, Cohen P. Analysis of the in vivo phosphorylation state of protein phosphatase inhibitor-2 from rabbit skeletal muscle by fast-atom bombardment mass spectrometry. Biochimica Et Biophysica Acta. 929: 208-19. PMID 3036252 DOI: 10.1016/0167-4889(87)90178-9 |
0.625 |
|
| 1986 |
Holmes CF, Campbell DG, Caudwell FB, Aitken A, Cohen P. The protein phosphatases involved in cellular regulation. Primary structure of inhibitor-2 from rabbit skeletal muscle. European Journal of Biochemistry. 155: 173-82. PMID 3512270 |
0.53 |
|
| 1986 |
Cohen P, Holmes CF, Poulter L, Gibson B, Williams DH. Identification of the C-terminus of rabbit skeletal muscle glycogen synthase. Biochemical and Biophysical Research Communications. 137: 542-5. PMID 3087361 DOI: 10.1016/0006-291X(86)91244-1 |
0.497 |
|
| 1986 |
Holmes CF, Kuret J, Chisholm AA, Cohen P. Identification of the sites on rabbit skeletal muscle protein phosphatase inhibitor-2 phosphorylated by casein kinase-II. Biochimica Et Biophysica Acta. 870: 408-16. PMID 3008843 DOI: 10.1016/0167-4838(86)90248-7 |
0.589 |
|
| 1984 |
Aitken A, Holmes CF, Campbell DG, Resink TJ, Cohen P, Leung CT, Williams DH. Amino acid sequence at the site on protein phosphatase inhibitor-2, phosphorylated by glycogen synthase kinase-3. Biochimica Et Biophysica Acta. 790: 288-91. PMID 6091765 DOI: 10.1016/0167-4838(84)90034-7 |
0.573 |
|
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