| Year |
Citation |
Score |
| 2023 |
Daskalova SM, Dedkova LM, Maini R, Talukder P, Bai X, Chowdhury SR, Zhang C, Nangreave RC, Hecht SM. Elongation Factor P Modulates the Incorporation of Structurally Diverse Noncanonical Amino Acids into Dihydrofolate Reductase. Journal of the American Chemical Society. PMID 37871253 DOI: 10.1021/jacs.3c07524 |
0.523 |
|
| 2020 |
Hui C, Tomilov A, Garcia C, Jiang X, Fash DM, Khdour OM, Rosso C, Filippini G, Prato M, Graham J, Hecht S, Havel P, Cortopassi G. Novel idebenone analogs block Shc's access to insulin receptor to improve insulin sensitivity. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 132: 110823. PMID 33045613 DOI: 10.1016/j.biopha.2020.110823 |
0.755 |
|
| 2020 |
Daskalova SM, Eisenhauer BM, Gao M, Feng X, Ji X, Cheng Q, Fahmi N, Khdour OM, Chen S, Hecht SM. An assay for DNA polymerase β lyase inhibitors that engage the catalytic nucleophile for binding. Bioorganic & Medicinal Chemistry. 28: 115642. PMID 32773093 DOI: 10.1016/J.Bmc.2020.115642 |
0.73 |
|
| 2020 |
Zhang C, Chen S, Dedkova LM, Hecht SM. Effects of Nucleobase Amino Acids on the Binding of Rob to its Promoter DNA: Differential Alteration of DNA Affinity and Phenotype. Biochemistry. PMID 32412234 DOI: 10.1021/Acs.Biochem.0C00290 |
0.39 |
|
| 2020 |
Zhang C, Chen S, Bai X, Dedkova LM, Hecht SM. Alteration of Transcriptional Regulator Rob In Vivo: Enhancement of Promoter DNA Binding and Antibiotic Resistance in the Presence of Nucleobase Amino Acids. Biochemistry. PMID 32157864 DOI: 10.1021/Acs.Biochem.0C00103 |
0.374 |
|
| 2019 |
Dedkova LM, Hecht SM. Expanding the Scope of Protein Synthesis Using Modified Ribosomes. Journal of the American Chemical Society. PMID 30901982 DOI: 10.1021/Jacs.9B02109 |
0.328 |
|
| 2019 |
Chen S, Ji X, Gao M, Dedkova LM, Hecht SM. In Cellulo Synthesis of Proteins Containing a Fluorescent Oxazole Amino Acid. Journal of the American Chemical Society. PMID 30889951 DOI: 10.1021/Jacs.8B12767 |
0.328 |
|
| 2018 |
Khdour OM, Bandyopadhyay I, Visavadiya NP, Roy Chowdhury S, Hecht SM. Phenothiazine antioxidants increase mitochondrial biogenesis and frataxin levels in Friedreich's ataxia cells. Medchemcomm. 9: 1491-1501. PMID 30288223 DOI: 10.1039/C8Md00274F |
0.768 |
|
| 2018 |
Bandyopadhyay I, Chowdhury SR, Visavadiya NP, Hecht SM, Khdour OM. Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels. Data in Brief. 20: 1105-1114. PMID 30225325 DOI: 10.1016/J.Dib.2018.08.156 |
0.32 |
|
| 2018 |
Khdour OM, Bandyopadhyay I, Chowdhury SR, Visavadiya NP, Hecht SM. Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia. Bioorganic & Medicinal Chemistry. PMID 29773347 DOI: 10.1016/J.Bmc.2018.05.005 |
0.32 |
|
| 2018 |
Daskalova SM, Bai X, Hecht SM. Study of the Lyase Activity of Human DNA Polymerase β Using Analogues of the Intermediate Schiff Base Complex. Biochemistry. PMID 29625008 DOI: 10.1021/Acs.Biochem.8B00308 |
0.362 |
|
| 2018 |
Gao M, Daniel D, Zou H, Jiang S, Lin S, Huang C, Hecht SM, Chen S. Rapid detection of a dengue virus RNA sequence with single molecule sensitivity using tandem toehold-mediated displacement reactions. Chemical Communications (Cambridge, England). PMID 29319084 DOI: 10.1039/C7Cc09131A |
0.319 |
|
| 2017 |
Roy Chowdhury S, Khdour OM, Bandyopadhyay I, Hecht SM. Lipophilic methylene violet analogues as modulators of mitochondrial function and dysfunction. Bioorganic & Medicinal Chemistry. PMID 28927904 DOI: 10.1016/J.Bmc.2017.08.021 |
0.78 |
|
| 2017 |
Chen S, Maini R, Bai X, Nangreave RC, Dedkova LM, Hecht SM. Incorporation of Phosphorylated Tyrosine into Proteins: In Vitro Translation and Study of Phosphorylated IKB-α and its Interaction with NF-ΚB. Journal of the American Chemical Society. PMID 28898075 DOI: 10.1021/Jacs.7B05168 |
0.589 |
|
| 2017 |
Zhang Y, Chevalier A, Khdour OM, Soto LM, Hecht SM. Inhibition of Human Cancer Cell Growth by Analogues of Antimycin A. Planta Medica. PMID 28597454 DOI: 10.1055/S-0043-112343 |
0.332 |
|
| 2017 |
Bai X, Talukder P, Daskalova SM, Roy B, Chen S, Li Z, Dedkova LM, Hecht SM. Enhanced Binding Affinity for an i-Motif DNA Substrate Exhibited by a Protein Containing Nucleobase Amino Acids. Journal of the American Chemical Society. PMID 28263595 DOI: 10.1021/Jacs.6B11825 |
0.619 |
|
| 2017 |
Chevalier A, Khdour OM, Schmierer M, Bandyopadhyay I, Hecht SM. Influence of substituent heteroatoms on the cytoprotective properties of pyrimidinol antioxidants. Bioorganic & Medicinal Chemistry. PMID 28189395 DOI: 10.1016/J.Bmc.2017.01.030 |
0.305 |
|
| 2016 |
Daskalova SM, Bhattacharya C, Dedkova LM, Hecht SM. Probing the Flexibility of the Catalytic Nucleophile in the Lyase Catalytic Pocket of Human DNA Polymerase β with Unnatural Lysine Analogues. Biochemistry. PMID 28005340 DOI: 10.1021/Acs.Biochem.6B00807 |
0.612 |
|
| 2016 |
Zhang Y, Jiang S, Zhang D, Bai X, Hecht SM, Chen S. DNA-affibody nanoparticles for inhibiting breast cancer cells overexpressing HER2. Chemical Communications (Cambridge, England). PMID 27975087 DOI: 10.1039/C6Cc08495H |
0.31 |
|
| 2016 |
Chevalier A, Alam MP, Khdour OM, Schmierer M, Arce PM, Cripe CD, Hecht SM. Optimization of pyrimidinol antioxidants as mitochondrial protective agents: ATP production and metabolic stability. Bioorganic & Medicinal Chemistry. PMID 27624526 DOI: 10.1016/J.Bmc.2016.08.039 |
0.757 |
|
| 2016 |
Kendrick S, Kang HJ, Alam MP, Madathil MM, Agrawal P, Gokhale V, Yang D, Hecht SM, Hurley LH. Correction to "The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure". Journal of the American Chemical Society. PMID 27571358 DOI: 10.1021/jacs.6b07292 |
0.763 |
|
| 2016 |
Roy B, Talukder P, Kang HJ, Tsuen SS, Alam MP, Hurley LH, Hecht SM. Interaction of Individual Structural Domains of hnRNP LL with the BCL2 Promoter i-Motif DNA. Journal of the American Chemical Society. PMID 27483029 DOI: 10.1021/Jacs.6B05036 |
0.81 |
|
| 2016 |
Talukder P, Dedkova LM, Ellington AD, Yakovchuk P, Lim J, Anslyn EV, Hecht SM. Synthesis of alanyl nucleobase amino acids and their incorporation into proteins. Bioorganic & Medicinal Chemistry. PMID 27452282 DOI: 10.1016/J.Bmc.2016.07.008 |
0.354 |
|
| 2016 |
Chowdhury SR, Chauhan PS, Dedkova LM, Bai X, Chen S, Talukder P, Hecht SM. Synthesis and Evaluation of a Library of Fluorescent Dipeptidomimetic Analogues as Substrates for Modified Bacterial Ribosomes. Biochemistry. PMID 27050631 DOI: 10.1021/Acs.Biochem.6B00102 |
0.342 |
|
| 2015 |
Talukder P, Chen S, Roy B, Yakovchuk P, Spiering MM, Alam MP, Mathilakathu Madathil M, Bhattacharya C, Benkovic SJ, Hecht SM. Cyanotryptophans as Novel Fluorescent Probes for Studying Protein Conformational Changes and DNA-Protein Interaction. Biochemistry. PMID 26618501 DOI: 10.1021/Acs.Biochem.5B01085 |
0.785 |
|
| 2015 |
Roy Chowdhury S, Maini R, Dedkova LM, Hecht SM. Synthesis of fluorescent dipeptidomimetics and their ribosomal incorporation into green fluorescent protein. Bioorganic & Medicinal Chemistry Letters. PMID 26351043 DOI: 10.1016/J.Bmcl.2015.08.073 |
0.783 |
|
| 2015 |
Maini R, Dedkova LM, Paul R, Madathil MM, Chowdhury SR, Chen S, Hecht SM. Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro. Journal of the American Chemical Society. 137: 11206-9. PMID 26301427 DOI: 10.1021/Jacs.5B03135 |
0.695 |
|
| 2015 |
Gerasimova YV, Yakovchuk P, Dedkova LM, Hecht SM, Kolpashchikov DM. Expedited quantification of mutant ribosomal RNA by binary deoxyribozyme (BiDz) sensors. Rna (New York, N.Y.). PMID 26289345 DOI: 10.1261/Rna.052613.115 |
0.31 |
|
| 2015 |
Maini R, Chowdhury SR, Dedkova LM, Roy B, Daskalova SM, Paul R, Chen S, Hecht SM. Protein Synthesis with Ribosomes Selected for the Incorporation of β-Amino Acids. Biochemistry. 54: 3694-706. PMID 25982410 DOI: 10.1021/Acs.Biochem.5B00389 |
0.739 |
|
| 2015 |
Yu Z, Paul R, Bhattacharya C, Bozeman TC, Rishel MJ, Hecht SM. Structural features facilitating tumor cell targeting and internalization by bleomycin and its disaccharide. Biochemistry. 54: 3100-9. PMID 25905565 DOI: 10.1021/Acs.Biochem.5B00277 |
0.779 |
|
| 2015 |
Mastroeni D, Khdour OM, Arce PM, Hecht SM, Coleman PD. Novel antioxidants protect mitochondria from the effects of oligomeric amyloid beta and contribute to the maintenance of epigenome function. Acs Chemical Neuroscience. 6: 588-98. PMID 25668062 DOI: 10.1021/Cn500323Q |
0.304 |
|
| 2015 |
Bernatchez JA, Paul R, Tchesnokov EP, Ngure M, Beilhartz GL, Berghuis AM, Lavoie R, Li L, Auger A, Melnyk RA, Grobler JA, Miller MD, Hazuda DJ, Hecht SM, Götte M. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. The Journal of Biological Chemistry. 290: 1474-84. PMID 25355312 DOI: 10.1074/Jbc.M114.614305 |
0.53 |
|
| 2015 |
Roy Chowdhury S, Maini R, Dedkova LM, Hecht SM. Synthesis of fluorescent dipeptidomimetics and their ribosomal incorporation into green fluorescent protein Bioorganic and Medicinal Chemistry Letters. DOI: 10.1016/j.bmcl.2015.08.073 |
0.775 |
|
| 2014 |
Yu X, Talukder P, Bhattacharya C, Fahmi NE, Lines JA, Dedkova LM, LaBaer J, Hecht SM, Chen S. Probing of CD4 binding pocket of HIV-1 gp120 glycoprotein using unnatural phenylalanine analogues. Bioorganic & Medicinal Chemistry Letters. 24: 5699-703. PMID 25453804 DOI: 10.1016/J.Bmcl.2014.10.058 |
0.732 |
|
| 2014 |
Talukder P, Chen S, Liu CT, Baldwin EA, Benkovic SJ, Hecht SM. Tryptophan-based fluorophores for studying protein conformational changes. Bioorganic & Medicinal Chemistry. 22: 5924-34. PMID 25284250 DOI: 10.1016/J.Bmc.2014.09.015 |
0.329 |
|
| 2014 |
Madathil MM, Bhattacharya C, Yu Z, Paul R, Rishel MJ, Hecht SM. Modified bleomycin disaccharides exhibiting improved tumor cell targeting. Biochemistry. 53: 6800-10. PMID 25272367 DOI: 10.1021/Bi501102Z |
0.793 |
|
| 2014 |
Tang C, Paul A, Alam MP, Roy B, Wilson WD, Hecht SM. A short DNA sequence confers strong bleomycin binding to hairpin DNAs. Journal of the American Chemical Society. 136: 13715-26. PMID 25188011 DOI: 10.1021/Ja505733U |
0.814 |
|
| 2014 |
Roy B, Tang C, Alam MP, Hecht SM. DNA methylation reduces binding and cleavage by bleomycin. Biochemistry. 53: 6103-12. PMID 25187079 DOI: 10.1021/Bi5010848 |
0.813 |
|
| 2014 |
Schroeder BR, Ghare MI, Bhattacharya C, Paul R, Yu Z, Zaleski PA, Bozeman TC, Rishel MJ, Hecht SM. The disaccharide moiety of bleomycin facilitates uptake by cancer cells. Journal of the American Chemical Society. 136: 13641-56. PMID 25184545 DOI: 10.1021/Ja507255G |
0.789 |
|
| 2014 |
Alam MP, Khdour OM, Arce PM, Chen Y, Roy B, Johnson WG, Dey S, Hecht SM. Cytoprotective pyridinol antioxidants as potential therapeutic agents for neurodegenerative and mitochondrial diseases. Bioorganic & Medicinal Chemistry. 22: 4935-47. PMID 25088548 DOI: 10.1016/J.Bmc.2014.06.040 |
0.79 |
|
| 2014 |
Bhattacharya C, Yu Z, Rishel MJ, Hecht SM. The carbamoylmannose moiety of bleomycin mediates selective tumor cell targeting. Biochemistry. 53: 3264-6. PMID 24811347 DOI: 10.1021/Bi500482Q |
0.785 |
|
| 2014 |
Kendrick S, Kang HJ, Alam MP, Madathil MM, Agrawal P, Gokhale V, Yang D, Hecht SM, Hurley LH. The dynamic character of the BCL2 promoter i-motif provides a mechanism for modulation of gene expression by compounds that bind selectively to the alternative DNA hairpin structure. Journal of the American Chemical Society. 136: 4161-71. PMID 24559410 DOI: 10.1021/Ja410934B |
0.784 |
|
| 2014 |
Roy B, Hecht SM. Hairpin DNA sequences bound strongly by bleomycin exhibit enhanced double-strand cleavage. Journal of the American Chemical Society. 136: 4382-93. PMID 24548300 DOI: 10.1021/Ja500414A |
0.606 |
|
| 2014 |
Talukder P, Chen S, Arce PM, Hecht SM. Efficient asymmetric synthesis of tryptophan analogues having useful photophysical properties. Organic Letters. 16: 556-9. PMID 24392870 DOI: 10.1021/Ol403429E |
0.336 |
|
| 2013 |
Khdour OM, Arce PM, Roy B, Hecht SM. An optimized pyrimidinol multifunctional radical quencher. Acs Medicinal Chemistry Letters. 4: 724-9. PMID 24900738 DOI: 10.1021/Ml400130Z |
0.549 |
|
| 2013 |
Madathil MM, Khdour OM, Jaruvangsanti J, Hecht SM. A structurally simplified analogue of geldanamycin exhibits neuroprotective activity. Acs Medicinal Chemistry Letters. 4: 953-7. PMID 24900591 DOI: 10.1021/Ml400207M |
0.307 |
|
| 2013 |
Chen S, Fahmi NE, Bhattacharya C, Wang L, Jin Y, Benkovic SJ, Hecht SM. Fluorescent biphenyl derivatives of phenylalanine suitable for protein modification. Biochemistry. 52: 8580-9. PMID 24152169 DOI: 10.1021/Bi401275V |
0.774 |
|
| 2013 |
Chen S, Fahmi NE, Wang L, Bhattacharya C, Benkovic SJ, Hecht SM. Detection of dihydrofolate reductase conformational change by FRET using two fluorescent amino acids. Journal of the American Chemical Society. 135: 12924-7. PMID 23941571 DOI: 10.1021/Ja403007R |
0.764 |
|
| 2013 |
Segerman ZJ, Roy B, Hecht SM. Characterization of bleomycin-mediated cleavage of a hairpin DNA library. Biochemistry. 52: 5315-27. PMID 23834496 DOI: 10.1021/Bi400779R |
0.614 |
|
| 2013 |
Fash DM, Khdour OM, Sahdeo SJ, Goldschmidt R, Jaruvangsanti J, Dey S, Arce PM, Collin VC, Cortopassi GA, Hecht SM. Effects of alkyl side chain modification of coenzyme Q10 on mitochondrial respiratory chain function and cytoprotection. Bioorganic & Medicinal Chemistry. 21: 2346-54. PMID 23473946 DOI: 10.1016/J.Bmc.2013.01.075 |
0.773 |
|
| 2013 |
Yu Z, Schmaltz RM, Bozeman TC, Paul R, Rishel MJ, Tsosie KS, Hecht SM. Selective tumor cell targeting by the disaccharide moiety of bleomycin. Journal of the American Chemical Society. 135: 2883-6. PMID 23379863 DOI: 10.1021/Ja311090E |
0.759 |
|
| 2013 |
Maini R, Nguyen DT, Chen S, Dedkova LM, Chowdhury SR, Alcala-Torano R, Hecht SM. Incorporation of β-amino acids into dihydrofolate reductase by ribosomes having modifications in the peptidyltransferase center. Bioorganic & Medicinal Chemistry. 21: 1088-96. PMID 23375097 DOI: 10.1016/J.Bmc.2013.01.002 |
0.563 |
|
| 2013 |
Goldschmidt R, Arce PM, Khdour OM, Collin VC, Dey S, Jaruvangsanti J, Fash DM, Hecht SM. Effects of cytoprotective antioxidants on lymphocytes from representative mitochondrial neurodegenerative diseases. Bioorganic & Medicinal Chemistry. 21: 969-78. PMID 23313093 DOI: 10.1016/J.Bmc.2012.11.051 |
0.786 |
|
| 2013 |
Segerman ZJ, Roy B, Hecht SM. Correction to Characterization of Bleomycin-Mediated Cleavage of a Hairpin DNA Library Biochemistry. 52: 6300-6300. DOI: 10.1021/Bi401115D |
0.605 |
|
| 2012 |
Mrozowski RM, Vemula R, Wu B, Zhang Q, Schroeder BR, Hilinski MK, Clark DE, Hecht SM, O'Doherty GA, Lannigan DA. Improving the affinity of SL0101 for RSK using structure-based design. Acs Medicinal Chemistry Letters. 4: 175-179. PMID 23519677 DOI: 10.1021/Ml300298V |
0.759 |
|
| 2012 |
Madathil MM, Khdour OM, Jaruvangsanti J, Hecht SM. Synthesis and biological activities of N-(3-carboxylpropyl)-5-amino-2-hydroxy-3-tridecyl-1,4-benzoquinone and analogues. Journal of Natural Products. 75: 2209-15. PMID 23190044 DOI: 10.1021/Np3007099 |
0.331 |
|
| 2012 |
Chen S, Wang L, Fahmi NE, Benkovic SJ, Hecht SM. Two pyrenylalanines in dihydrofolate reductase form an excimer enabling the study of protein dynamics. Journal of the American Chemical Society. 134: 18883-5. PMID 23116258 DOI: 10.1021/Ja307179Q |
0.698 |
|
| 2012 |
Bozeman TC, Nanjunda R, Tang C, Liu Y, Segerman ZJ, Zaleski PA, Wilson WD, Hecht SM. Dynamics of bleomycin interaction with a strongly bound hairpin DNA substrate, and implications for cleavage of the bound DNA. Journal of the American Chemical Society. 134: 17842-5. PMID 23072568 DOI: 10.1021/Ja306233E |
0.801 |
|
| 2012 |
Arce PM, Goldschmidt R, Khdour OM, Madathil MM, Jaruvangsanti J, Dey S, Fash DM, Armstrong JS, Hecht SM. Analysis of the structural and mechanistic factors in antioxidants that preserve mitochondrial function and confer cytoprotection. Bioorganic & Medicinal Chemistry. 20: 5188-201. PMID 22883028 DOI: 10.1016/J.Bmc.2012.07.005 |
0.785 |
|
| 2012 |
Cai X, Khdour OM, Jaruvangsanti J, Hecht SM. Simplified bicyclic pyridinol analogues protect mitochondrial function. Bioorganic & Medicinal Chemistry. 20: 3584-95. PMID 22560834 DOI: 10.1016/J.Bmc.2012.03.075 |
0.51 |
|
| 2012 |
Zaleski PA, Maini R, Leiris SJ, Elban MA, Hecht SM. Synthesis and biological activities of topopyrones. Journal of Natural Products. 75: 577-85. PMID 22462811 DOI: 10.1021/Np200777Z |
0.812 |
|
| 2012 |
Chen S, Fahmi NE, Nangreave RC, Mehellou Y, Hecht SM. Synthesis of pdCpAs and transfer RNAs activated with thiothreonine and derivatives. Bioorganic & Medicinal Chemistry. 20: 2679-89. PMID 22405920 DOI: 10.1016/J.Bmc.2012.02.024 |
0.716 |
|
| 2012 |
Dedkova LM, Fahmi NE, Paul R, del Rosario M, Zhang L, Chen S, Feder G, Hecht SM. β-Puromycin selection of modified ribosomes for in vitro incorporation of β-amino acids. Biochemistry. 51: 401-15. PMID 22145951 DOI: 10.1021/Bi2016124 |
0.752 |
|
| 2011 |
Chen S, Zhang Y, Hecht SM. p-Thiophenylalanine-induced DNA cleavage and religation activity of a modified vaccinia topoisomerase IB. Biochemistry. 50: 9340-51. PMID 21942719 DOI: 10.1021/Bi201291P |
0.372 |
|
| 2011 |
Nangreave RC, Dedkova LM, Chen S, Hecht SM. A new strategy for the synthesis of bisaminoacylated tRNAs. Organic Letters. 13: 4906-9. PMID 21861452 DOI: 10.1021/Ol201993C |
0.341 |
|
| 2011 |
Khdour OM, Lu J, Hecht SM. An acetate prodrug of a pyridinol-based vitamin E analogue. Pharmaceutical Research. 28: 2896-909. PMID 21732153 DOI: 10.1007/S11095-011-0491-9 |
0.303 |
|
| 2011 |
Duca M, Trindle CO, Hecht SM. Structural basis for the exceptional stability of bisaminoacylated nucleotides and transfer RNAs. Journal of the American Chemical Society. 133: 11368-77. PMID 21648486 DOI: 10.1021/Ja203994E |
0.331 |
|
| 2011 |
Cai X, Zaleski PA, Cagir A, Hecht SM. Deglycobleomycin A6 analogues modified in the methylvalerate moiety. Bioorganic & Medicinal Chemistry. 19: 3831-44. PMID 21612932 DOI: 10.1016/J.Bmc.2011.04.047 |
0.82 |
|
| 2010 |
Giroux RA, Hecht SM. Characterization of bleomycin cleavage sites in strongly bound hairpin DNAs. Journal of the American Chemical Society. 132: 16987-96. PMID 21047076 DOI: 10.1021/Ja107228C |
0.408 |
|
| 2010 |
Lu J, Cai X, Hecht SM. Concise synthesis of bicyclic pyridinol antioxidants. Organic Letters. 12: 5189-91. PMID 20939522 DOI: 10.1021/Ol102217C |
0.508 |
|
| 2010 |
Lu J, Khdour OM, Armstrong JS, Hecht SM. Design, synthesis, and evaluation of an α-tocopherol analogue as a mitochondrial antioxidant. Bioorganic & Medicinal Chemistry. 18: 7628-38. PMID 20884213 DOI: 10.1016/J.Bmc.2010.08.030 |
0.32 |
|
| 2010 |
Leiris SJ, Khdour OM, Segerman ZJ, Tsosie KS, Chapuis JC, Hecht SM. Synthesis and evaluation of verticipyrone analogues as mitochondrial complex I inhibitors. Bioorganic & Medicinal Chemistry. 18: 3481-93. PMID 20456960 DOI: 10.1016/J.Bmc.2010.03.070 |
0.314 |
|
| 2010 |
Katano K, An H, Aoyagi Y, Overhand M, Sucheck SJ, Stevens WCJ, Hess CD, Zhou X, Hecht SM. ChemInform Abstract: Total Synthesis of Bleomycin Group Antibiotics. Total Syntheses of Bleomycin Demethyl A2, Bleomycin A2, and Decarbamoyl Bleomycin Demethyl A2. Cheminform. 30: no-no. DOI: 10.1002/chin.199915272 |
0.513 |
|
| 2010 |
LOCKE EP, HECHT SM. ChemInform Abstract: Enantiospecific Total Synthesis of (+)- and (-)-Avarone and -Avarol. Cheminform. 28: no-no. DOI: 10.1002/chin.199724187 |
0.761 |
|
| 2010 |
OVERHAND M, HECHT SM. ChemInform Abstract: A Concise Synthesis of the Antifungal Agent (+)-Preussin. Cheminform. 26: no-no. DOI: 10.1002/chin.199511262 |
0.542 |
|
| 2009 |
Kendrick S, Akiyama Y, Hecht SM, Hurley LH. The i-motif in the bcl-2 P1 promoter forms an unexpectedly stable structure with a unique 8:5:7 loop folding pattern. Journal of the American Chemical Society. 131: 17667-76. PMID 19908860 DOI: 10.1021/Ja9076292 |
0.366 |
|
| 2009 |
Khan QA, Lu J, Hecht SM. Calothrixins, a new class of human DNA topoisomerase I poisons. Journal of Natural Products. 72: 438-42. PMID 19203291 DOI: 10.1021/Np8007232 |
0.353 |
|
| 2009 |
Chapuis JC, Schmaltz RM, Tsosie KS, Belohlavek M, Hecht SM. Carbohydrate dependent targeting of cancer cells by bleomycin-microbubble conjugates. Journal of the American Chemical Society. 131: 2438-9. PMID 19187019 DOI: 10.1021/Ja8091104 |
0.772 |
|
| 2009 |
Ma Q, Akiyama Y, Xu Z, Konishi K, Hecht SM. Identification and cleavage site analysis of DNA sequences bound strongly by bleomycin. Journal of the American Chemical Society. 131: 2013-22. PMID 19146404 DOI: 10.1021/Ja808629S |
0.403 |
|
| 2009 |
Chapuis JC, Khdour O, Cai X, Lu J, Hecht SM. Synthesis and characterization of Deltalac-acetogenins that potently inhibit mitochondrial complex I. Bioorganic & Medicinal Chemistry. 17: 2204-9. PMID 19027304 DOI: 10.1016/J.Bmc.2008.10.071 |
0.479 |
|
| 2008 |
Duca M, Chen S, Hecht SM. Modeling the reactive properties of tandemly activated tRNAs. Organic & Biomolecular Chemistry. 6: 3292-9. PMID 18802635 DOI: 10.1039/B806790B |
0.344 |
|
| 2008 |
Chen S, Hecht SM. Synthesis of pdCpAs and transfer RNAs activated with derivatives of aspartic acid and cysteine. Bioorganic & Medicinal Chemistry. 16: 9023-31. PMID 18790645 DOI: 10.1016/J.Bmc.2008.08.036 |
0.343 |
|
| 2008 |
Khan QA, Elban MA, Hecht SM. The topopyrones poison human DNA topoisomerases I and II. Journal of the American Chemical Society. 130: 12888-9. PMID 18774813 DOI: 10.1021/Ja805421B |
0.81 |
|
| 2008 |
Akiyama Y, Ma Q, Edgar E, Laikhter A, Hecht SM. Identification of strong DNA binding motifs for bleomycin. Journal of the American Chemical Society. 130: 9650-1. PMID 18597467 DOI: 10.1021/Ja802905G |
0.4 |
|
| 2008 |
Akiyama Y, Ma Q, Edgar E, Laikhter A, Hecht SM. A novel DNA hairpin substrate for bleomycin. Organic Letters. 10: 2127-30. PMID 18444656 DOI: 10.1021/Ol800445X |
0.4 |
|
| 2008 |
Yakovleva L, Chen S, Hecht SM, Shuman S. Chemical and traditional mutagenesis of vaccinia DNA topoisomerase provides insights to cleavage site recognition and transesterification chemistry. The Journal of Biological Chemistry. 283: 16093-103. PMID 18367446 DOI: 10.1074/Jbc.M801595200 |
0.401 |
|
| 2008 |
Gao Z, Maloney DJ, Dedkova LM, Hecht SM. Inhibitors of DNA polymerase beta: activity and mechanism. Bioorganic & Medicinal Chemistry. 16: 4331-40. PMID 18343122 DOI: 10.1016/J.Bmc.2008.02.071 |
0.365 |
|
| 2008 |
Duca M, Chen S, Hecht SM. Aminoacylation of transfer RNAs with one and two amino acids. Methods (San Diego, Calif.). 44: 87-99. PMID 18241791 DOI: 10.1016/J.Ymeth.2007.10.007 |
0.345 |
|
| 2008 |
Elban MA, Hecht SM. Total synthesis of the topopyrones: a new class of topoisomerase I poisons. The Journal of Organic Chemistry. 73: 785-93. PMID 18184012 DOI: 10.1021/Jo702487R |
0.787 |
|
| 2008 |
Elban MA, Hecht SM. ChemInform Abstract: Total Synthesis of the Topopyrones: A New Class of Topoisomerase I Poisons. Cheminform. 39. DOI: 10.1002/chin.200822210 |
0.778 |
|
| 2007 |
Ma Q, Xu Z, Schroeder BR, Sun W, Wei F, Hashimoto S, Konishi K, Leitheiser CJ, Hecht SM. Biochemical evaluation of a 108-member deglycobleomycin library: viability of a selection strategy for identifying bleomycin analogues with altered properties. Journal of the American Chemical Society. 129: 12439-52. PMID 17887752 DOI: 10.1021/Ja0722729 |
0.814 |
|
| 2007 |
Maloney DJ, Ghanem N, Zhou J, Hecht SM. Positional assignment of differentially substituted bisaminoacylated pdCpAs. Organic & Biomolecular Chemistry. 5: 3135-8. PMID 17878972 DOI: 10.1039/B708786A |
0.426 |
|
| 2007 |
Elban MA, Chapuis JC, Li M, Hecht SM. Synthesis and biological evaluation of cepharadiones A and B and related dioxoaporphines. Bioorganic & Medicinal Chemistry. 15: 6119-25. PMID 17624787 DOI: 10.1016/J.Bmc.2007.06.035 |
0.798 |
|
| 2007 |
Karginov VA, Nestorovich EM, Schmidtmann F, Robinson TM, Yohannes A, Fahmi NE, Bezrukov SM, Hecht SM. Inhibition of S. aureus alpha-hemolysin and B. anthracis lethal toxin by beta-cyclodextrin derivatives. Bioorganic & Medicinal Chemistry. 15: 5424-31. PMID 17572091 DOI: 10.1016/J.Bmc.2007.05.058 |
0.694 |
|
| 2007 |
Smith JA, Maloney DJ, Hecht SM, Lannigan DA. Structural basis for the activity of the RSK-specific inhibitor, SL0101. Bioorganic & Medicinal Chemistry. 15: 5018-34. PMID 17512736 DOI: 10.1016/J.Bmc.2007.03.087 |
0.301 |
|
| 2007 |
Duca M, Maloney DJ, Lodder M, Wang B, Hecht SM. Synthesis of bisaminoacylated pdCpAs and tandemly activated transfer RNAs. Bioorganic & Medicinal Chemistry. 15: 4629-42. PMID 17490885 DOI: 10.1016/J.Bmc.2007.03.088 |
0.624 |
|
| 2007 |
Choudhury AK, Golovine SY, Dedkova LM, Hecht SM. Synthesis of proteins containing modified arginine residues. Biochemistry. 46: 4066-76. PMID 17346032 DOI: 10.1021/Bi062042R |
0.328 |
|
| 2007 |
Fahmi NE, Dedkova L, Wang B, Golovine S, Hecht SM. Site-specific incorporation of glycosylated serine and tyrosine derivatives into proteins. Journal of the American Chemical Society. 129: 3586-97. PMID 17338522 DOI: 10.1021/Ja067466N |
0.78 |
|
| 2007 |
Klarmann GJ, Eisenhauer BM, Zhang Y, Gotte M, Pata JD, Chatterjee DK, Hecht SM, Le Grice SF. Investigating the "steric gate" of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by targeted insertion of unnatural amino acids. Biochemistry. 46: 2118-26. PMID 17274599 DOI: 10.1021/Bi061772W |
0.322 |
|
| 2006 |
Dedkova LM, Fahmi NE, Golovine SY, Hecht SM. Construction of modified ribosomes for incorporation of D-amino acids into proteins. Biochemistry. 45: 15541-51. PMID 17176075 DOI: 10.1021/Bi060986A |
0.695 |
|
| 2006 |
Tao ZF, Konishi K, Keith G, Hecht SM. An efficient mammalian transfer RNA target for bleomycin. Journal of the American Chemical Society. 128: 14806-7. PMID 17105281 DOI: 10.1021/Ja066187X |
0.308 |
|
| 2006 |
Karginov VA, Nestorovich EM, Yohannes A, Robinson TM, Fahmi NE, Schmidtmann F, Hecht SM, Bezrukov SM. Search for cyclodextrin-based inhibitors of anthrax toxins: synthesis, structural features, and relative activities. Antimicrobial Agents and Chemotherapy. 50: 3740-53. PMID 16982795 DOI: 10.1128/Aac.00693-06 |
0.693 |
|
| 2006 |
Elban MA, Sun W, Eisenhauer BM, Gao R, Hecht SM. Synthesis and biological evaluation of 10,11-methylenedioxy-14-azacamptothecin. Organic Letters. 8: 3513-6. PMID 16869648 DOI: 10.1021/Ol0611604 |
0.809 |
|
| 2006 |
Gao R, Zhang Y, Dedkova L, Choudhury AK, Rahier NJ, Hecht SM. Effects of modification of the active site tyrosine of human DNA topoisomerase I. Biochemistry. 45: 8402-10. PMID 16819839 DOI: 10.1021/Bi0605179 |
0.539 |
|
| 2006 |
Maloney DJ, Chen S, Hecht SM. Stereoselective synthesis of the atropisomers of myristinin B/C. Organic Letters. 8: 1925-7. PMID 16623586 DOI: 10.1021/Ol060511B |
0.336 |
|
| 2006 |
Clement JA, Li M, Hecht SM, Kingston DG. Bioactive isomalabaricane triterpenoids from Rhabdastrella globostellata that stabilize the binding of DNA polymerase beta to DNA. Journal of Natural Products. 69: 373-6. PMID 16562838 DOI: 10.1021/Np0504107 |
0.59 |
|
| 2006 |
Wang B, Zhou J, Lodder M, Anderson RD, Hecht SM. Tandemly activated tRNAs as participants in protein synthesis. The Journal of Biological Chemistry. 281: 13865-8. PMID 16556606 DOI: 10.1074/Jbc.C600018200 |
0.757 |
|
| 2006 |
Arimondo PB, Thomas CJ, Oussedik K, Baldeyrou B, Mahieu C, Halby L, Guianvarc'h D, Lansiaux A, Hecht SM, Bailly C, Giovannangeli C. Exploring the cellular activity of camptothecin-triple-helix-forming oligonucleotide conjugates. Molecular and Cellular Biology. 26: 324-33. PMID 16354702 DOI: 10.1128/Mcb.26.1.324-333.2006 |
0.417 |
|
| 2006 |
Karginov VA, Yohannes A, Robinson TM, Fahmi NE, Alibek K, Hecht SM. Beta-cyclodextrin derivatives that inhibit anthrax lethal toxin. Bioorganic & Medicinal Chemistry. 14: 33-40. PMID 16169738 DOI: 10.1016/J.Bmc.2005.07.054 |
0.689 |
|
| 2005 |
Deng JZ, Starck SR, Li S, Hecht SM. (+)-Myristinins A and D from Knema elegans, which inhibit DNA polymerase beta and cleave DNA. Journal of Natural Products. 68: 1625-8. PMID 16309311 DOI: 10.1021/Np058064G |
0.389 |
|
| 2005 |
Maloney DJ, Hecht SM. A stereocontrolled synthesis of delta-trans-tocotrienoloic acid. Organic Letters. 7: 4297-300. PMID 16146411 DOI: 10.1021/Ol051849T |
0.321 |
|
| 2005 |
Pham VC, Ma J, Thomas SJ, Xu Z, Hecht SM. Alkaloids from Alangium javanicum and Alangium grisolleoides that mediate Cu2+-dependent DNA strand scission. Journal of Natural Products. 68: 1147-52. PMID 16124751 DOI: 10.1021/Np058013J |
0.362 |
|
| 2005 |
Hecht SM. Camptothecin: roles of the D and E rings in binding to the topoisomerase I-DNA covalent binary complex. Current Medicinal Chemistry. Anti-Cancer Agents. 5: 353-62. PMID 16101487 DOI: 10.2174/1568011054222373 |
0.353 |
|
| 2005 |
Lodder M, Wang B, Hecht SM. The N-pentenoyl protecting group for aminoacyl-tRNAs. Methods (San Diego, Calif.). 36: 245-51. PMID 16076450 DOI: 10.1016/J.Ymeth.2005.04.002 |
0.614 |
|
| 2005 |
Tian L, Claeboe CD, Hecht SM, Shuman S. Mechanistic plasticity of DNA topoisomerase IB: phosphate electrostatics dictate the need for a catalytic arginine. Structure (London, England : 1993). 13: 513-20. PMID 15837190 DOI: 10.1016/J.Str.2005.02.001 |
0.395 |
|
| 2005 |
Deng JZ, Newman DJ, Hecht SM. Umbelactonyl cinnamate derivatives from Crypteronia paniculata that mediate DNA strand scission. Journal of Natural Products. 68: 465-7. PMID 15787463 DOI: 10.1021/Np0401112 |
0.411 |
|
| 2005 |
Maloney DJ, Deng JZ, Starck SR, Gao Z, Hecht SM. (+)-Myristinin A, a naturally occurring DNA polymerase beta inhibitor and potent DNA-damaging agent. Journal of the American Chemical Society. 127: 4140-1. PMID 15783174 DOI: 10.1021/Ja042727J |
0.397 |
|
| 2005 |
Arimondo PB, Laco GS, Thomas CJ, Halby L, Pez D, Schmitt P, Boutorine A, Garestier T, Pommier Y, Hecht SM, Sun JS, Bailly C. Activation of camptothecin derivatives by conjugation to triple helix-forming oligonucleotides. Biochemistry. 44: 4171-80. PMID 15766244 DOI: 10.1021/Bi048031K |
0.414 |
|
| 2005 |
Maloney DJ, Hecht SM. Synthesis of a potent and selective inhibitor of p90 Rsk. Organic Letters. 7: 1097-9. PMID 15760148 DOI: 10.1021/Ol0500463 |
0.318 |
|
| 2005 |
Gao R, Zhang Y, Choudhury AK, Dedkova LM, Hecht SM. Analogues of vaccinia virus DNA topoisomerase I modified at the active site tyrosine. Journal of the American Chemical Society. 127: 3321-31. PMID 15755148 DOI: 10.1021/Ja044182Z |
0.504 |
|
| 2005 |
Rahier NJ, Cheng K, Gao R, Eisenhauer BM, Hecht SM. Synthesis of 14-azacamptothecin, a water-soluble topoisomerase I poison. Organic Letters. 7: 835-7. PMID 15727453 DOI: 10.1021/Ol0400701 |
0.466 |
|
| 2005 |
Ma J, Jones SH, Hecht SM. A dihydroflavonol glucoside from Commiphora africana that mediates DNA strand scission. Journal of Natural Products. 68: 115-7. PMID 15679332 DOI: 10.1021/Np0400510 |
0.363 |
|
| 2005 |
Rahier NJ, Eisenhauer BM, Gao R, Thomas SJ, Hecht SM. On the role of E-ring oxygen atoms in the binding of camptothecin to the topoisomerase I-DNA covalent binary complex. Bioorganic & Medicinal Chemistry. 13: 1381-6. PMID 15670945 DOI: 10.1016/J.Bmc.2004.11.011 |
0.504 |
|
| 2005 |
Ma J, Jones SH, Marshall R, Wu X, Hecht SM. DNA topoisomerase I inhibitors from Rinorea anguifera. Bioorganic & Medicinal Chemistry Letters. 15: 813-6. PMID 15664863 DOI: 10.1016/J.Bmcl.2004.10.095 |
0.362 |
|
| 2005 |
Cheng K, Rahier NJ, Eisenhauer BM, Gao R, Thomas SJ, Hecht SM. 14-azacamptothecin: a potent water-soluble topoisomerase I poison. Journal of the American Chemical Society. 127: 838-9. PMID 15656613 DOI: 10.1021/Ja0442769 |
0.55 |
|
| 2004 |
Cagir A, Eisenhauer BM, Gao R, Thomas SJ, Hecht SM. Synthesis and topoisomerase I inhibitory properties of luotonin A analogues. Bioorganic & Medicinal Chemistry. 12: 6287-99. PMID 15519171 DOI: 10.1016/J.Bmc.2004.08.052 |
0.771 |
|
| 2004 |
Chaturvedula VS, Zhou BN, Gao Z, Thomas SJ, Hecht SM, Kingston DG. New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase beta. Bioorganic & Medicinal Chemistry. 12: 6271-5. PMID 15519169 DOI: 10.1016/J.Bmc.2004.08.048 |
0.542 |
|
| 2004 |
Feng X, Gao Z, Li S, Jones SH, Hecht SM. DNA polymerase beta lyase inhibitors from Maytenus putterlickoides. Journal of Natural Products. 67: 1744-7. PMID 15497954 DOI: 10.1021/Np040057P |
0.38 |
|
| 2004 |
Cao S, Gao Z, Thomas SJ, Hecht SM, Lazo JS, Kingston DG. Marine sesquiterpenoids that inhibit the lyase activity of DNA polymerase beta. Journal of Natural Products. 67: 1716-8. PMID 15497946 DOI: 10.1021/np049849 |
0.551 |
|
| 2004 |
Ma J, Jones SH, Hecht SM. A coumarin from Mallotus resinosus that mediates DNA cleavage. Journal of Natural Products. 67: 1614-6. PMID 15387675 DOI: 10.1021/Np040129C |
0.389 |
|
| 2004 |
Li SS, Gao Z, Feng X, Hecht SM. Biscoumarin derivatives from Edgeworthia gardneri that inhibit the lyase activity of DNA polymerase beta. Journal of Natural Products. 67: 1608-10. PMID 15387673 DOI: 10.1021/Np040127S |
0.357 |
|
| 2004 |
Ma J, Jones SH, Marshall R, Johnson RK, Hecht SM. A DNA-damaging oxoaporphine alkaloid from Piper caninum. Journal of Natural Products. 67: 1162-4. PMID 15270572 DOI: 10.1021/Np040056X |
0.347 |
|
| 2004 |
Hu HY, Horton JK, Gryk MR, Prasad R, Naron JM, Sun DA, Hecht SM, Wilson SH, Mullen GP. Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. The Journal of Biological Chemistry. 279: 39736-44. PMID 15258144 DOI: 10.1074/Jbc.M402842200 |
0.369 |
|
| 2004 |
Li SS, Gao Z, Feng X, Jones SH, Hecht SM. Plant sterols as selective DNA polymerase beta lyase inhibitors and potentiators of bleomycin cytotoxicity. Bioorganic & Medicinal Chemistry. 12: 4253-8. PMID 15246101 DOI: 10.1016/J.Bmc.2004.05.016 |
0.329 |
|
| 2004 |
Prakash Chaturvedula VS, Hecht SM, Gao Z, Jones SH, Feng X, Kingston DG. New neolignans that inhibit DNA polymerase beta lyase. Journal of Natural Products. 67: 964-7. PMID 15217274 DOI: 10.1021/Np030507Y |
0.501 |
|
| 2004 |
Ma J, Jones SH, Hecht SM. Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum. Bioorganic & Medicinal Chemistry. 12: 3885-9. PMID 15210155 DOI: 10.1016/J.Bmc.2004.05.007 |
0.391 |
|
| 2004 |
Chaturvedula VS, Gao Z, Jones SH, Feng X, Hecht SM, Kingston DG. A new ursane triterpene from Monochaetum vulcanicum that inhibits DNA polymerase beta lyase. Journal of Natural Products. 67: 899-901. PMID 15165161 DOI: 10.1021/Np030531B |
0.524 |
|
| 2004 |
Gao R, Claeboe CD, Eisenhauer BM, Hecht SM. Identification of specific nonbridging phosphate oxygens important for DNA cleavage by human topoisomerase I. Biochemistry. 43: 6167-81. PMID 15147201 DOI: 10.1021/Bi040005Z |
0.514 |
|
| 2004 |
Ma J, Hecht SM. Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton. Chemical Communications (Cambridge, England). 1190-1. PMID 15136832 DOI: 10.1039/B402925A |
0.372 |
|
| 2004 |
Cagir A, Jones SH, Eisenhauer BM, Gao R, Hecht SM. Synthesis and biochemical properties of E-ring modified luotonin A derivatives. Bioorganic & Medicinal Chemistry Letters. 14: 2051-4. PMID 15080977 DOI: 10.1016/J.Bmcl.2004.02.069 |
0.771 |
|
| 2004 |
Thomas CJ, Rahier NJ, Hecht SM. Camptothecin: current perspectives. Bioorganic & Medicinal Chemistry. 12: 1585-604. PMID 15028252 DOI: 10.1016/J.Bmc.2003.11.036 |
0.365 |
|
| 2004 |
Rahier NJ, Eisenhauer BM, Gao R, Jones SH, Hecht SM. Water-soluble camptothecin derivatives that are intrinsic topoisomerase I poisons. Organic Letters. 6: 321-4. PMID 14748583 DOI: 10.1021/Ol030119N |
0.48 |
|
| 2004 |
Tian L, Claeboe CD, Hecht SM, Shuman S. Remote phosphate contacts trigger assembly of the active site of DNA topoisomerase IB. Structure (London, England : 1993). 12: 31-40. PMID 14725763 DOI: 10.1016/J.Str.2003.11.025 |
0.379 |
|
| 2004 |
Chaturvedula VSP, Gao Z, Thomas SH, Hecht SM, Kingston DGI. New norditerpenoids and a diterpenoid from a sponge that inhibit the lyase activity of DNA polymerase β Tetrahedron. 60: 9991-9995. DOI: 10.1016/J.Tet.2004.08.017 |
0.373 |
|
| 2003 |
Leitheiser CJ, Hecht SM. Solid-phase synthesis of deglycobleomycin and bleomycin. Current Opinion in Drug Discovery & Development. 6: 827-37. PMID 14758754 DOI: 10.1002/chin.200428251 |
0.79 |
|
| 2003 |
Prakash Chaturvedula VS, Gao Z, Hecht SM, Jones SH, Kingston DG. A new acylated oleanane triterpenoid from Couepia polyandra that inhibits the lyase activity of DNA polymerase beta. Journal of Natural Products. 66: 1463-5. PMID 14640519 DOI: 10.1021/Np0301893 |
0.551 |
|
| 2003 |
Cagir A, Tao ZF, Sucheck SJ, Hecht SM. Solid-phase synthesis and biochemical evaluation of conformationally constrained analogues of deglycobleomycin A5. Bioorganic & Medicinal Chemistry. 11: 5179-87. PMID 14604681 DOI: 10.1016/J.Bmc.2003.08.033 |
0.771 |
|
| 2003 |
Cagir A, Jones SH, Gao R, Eisenhauer BM, Hecht SM. Luotonin A. A naturally occurring human DNA topoisomerase I poison. Journal of the American Chemical Society. 125: 13628-9. PMID 14599178 DOI: 10.1021/Ja0368857 |
0.778 |
|
| 2003 |
Claeboe CD, Gao R, Hecht SM. 3'-modified oligonucleotides by reverse DNA synthesis. Nucleic Acids Research. 31: 5685-91. PMID 14500832 DOI: 10.1093/Nar/Gkg734 |
0.565 |
|
| 2003 |
Rishel MJ, Thomas CJ, Tao ZF, Vialas C, Leitheiser CJ, Hecht SM. Conformationally constrained analogues of bleomycin A5. Journal of the American Chemical Society. 125: 10194-205. PMID 12926941 DOI: 10.1021/Ja030057W |
0.817 |
|
| 2003 |
Tian L, Claeboe CD, Hecht SM, Shuman S. Guarding the genome: electrostatic repulsion of water by DNA suppresses a potent nuclease activity of topoisomerase IB. Molecular Cell. 12: 199-208. PMID 12887905 DOI: 10.1016/S1097-2765(03)00263-6 |
0.39 |
|
| 2003 |
Leitheiser CJ, Smith KL, Rishel MJ, Hashimoto S, Konishi K, Thomas CJ, Li C, McCormick MM, Hecht SM. Solid-phase synthesis of bleomycin group antibiotics. Construction of a 108-member deglycobleomycin library. Journal of the American Chemical Society. 125: 8218-27. PMID 12837092 DOI: 10.1021/Ja021388W |
0.816 |
|
| 2003 |
Dedkova LM, Fahmi NE, Golovine SY, Hecht SM. Enhanced D-amino acid incorporation into protein by modified ribosomes. Journal of the American Chemical Society. 125: 6616-7. PMID 12769555 DOI: 10.1021/Ja035141Q |
0.699 |
|
| 2003 |
Xu YM, Deng JZ, Ma J, Chen SN, Marshall R, Jones SH, Johnson RK, Hecht SM. DNA damaging activity of ellagic acid derivatives. Bioorganic & Medicinal Chemistry. 11: 1593-6. PMID 12628683 DOI: 10.1016/S0968-0896(02)00452-2 |
0.332 |
|
| 2003 |
Abraham AT, Lin JJ, Newton DL, Rybak S, Hecht SM. RNA cleavage and inhibition of protein synthesis by bleomycin. Chemistry & Biology. 10: 45-52. PMID 12573697 DOI: 10.1016/S1074-5521(02)00306-X |
0.7 |
|
| 2003 |
Hecht SM. Inhibitors of the lyase activity of DNA polymerase β Pharmaceutical Biology. 41: 68-77. DOI: 10.1080/1388020039051745 |
0.362 |
|
| 2002 |
Deng JZ, Marshall R, Jones SH, Johnson RK, Hecht SM. DNA-damaging agents from Crypteronia paniculata. Journal of Natural Products. 65: 1930-2. PMID 12502343 DOI: 10.1021/Np020285O |
0.317 |
|
| 2002 |
Thomas CJ, Chizhov AO, Leitheiser CJ, Rishel MJ, Konishi K, Tao ZF, Hecht SM. Solid-phase synthesis of bleomycin A(5) and three monosaccharide analogues: exploring the role of the carbohydrate moiety in RNA cleavage. Journal of the American Chemical Society. 124: 12926-7. PMID 12405801 DOI: 10.1021/Ja0208916 |
0.776 |
|
| 2002 |
Eisenhauer BM, Hecht SM. Site-specific incorporation of (aminooxy)acetic acid into proteins. Biochemistry. 41: 11472-8. PMID 12234190 DOI: 10.1021/Bi020352D |
0.336 |
|
| 2002 |
Anderson RD, Zhou J, Hecht SM. Fluorescence resonance energy transfer between unnatural amino acids in a structurally modified dihydrofolate reductase. Journal of the American Chemical Society. 124: 9674-5. PMID 12175203 DOI: 10.1021/Ja0205939 |
0.633 |
|
| 2002 |
Zou Y, Fahmi NE, Vialas C, Miller GM, Hecht SM. Total synthesis of deamido bleomycin a(2), the major catabolite of the antitumor agent bleomycin. Journal of the American Chemical Society. 124: 9476-88. PMID 12167044 DOI: 10.1021/Ja012741L |
0.754 |
|
| 2002 |
Tao ZF, Leitheiser CJ, Smith KL, Hashimoto S, Hecht SM. Solid-phase synthesis of deglycobleomycins: a C-terminal tetraamine linker that permits direct evaluation of resin-bound bleomycins. Bioconjugate Chemistry. 13: 426-34. PMID 12009930 DOI: 10.1021/Bc010083O |
0.823 |
|
| 2002 |
Thomas CJ, McCormick MM, Vialas C, Tao ZF, Leitheiser CJ, Rishel MJ, Wu X, Hecht SM. Alteration of the selectivity of DNA cleavage by a deglycobleomycin analogue containing a trithiazole moiety. Journal of the American Chemical Society. 124: 3875-84. PMID 11942824 DOI: 10.1021/Ja011820U |
0.817 |
|
| 2002 |
Smith KL, Tao ZF, Hashimoto S, Leitheiser CJ, Wu X, Hecht SM. Deglycobleomycin: solid-phase synthesis and DNA cleavage by the resin-bound ligand. Organic Letters. 4: 1079-82. PMID 11922787 DOI: 10.1021/Ol010293G |
0.814 |
|
| 2002 |
Wang B, Brown KC, Lodder M, Craik CS, Hecht SM. Chemically mediated site-specific proteolysis. Alteration of protein-protein interaction. Biochemistry. 41: 2805-13. PMID 11851428 DOI: 10.1021/Bi011762P |
0.637 |
|
| 2002 |
Arimondo PB, Boutorine A, Baldeyrou B, Bailly C, Kuwahara M, Hecht SM, Sun JS, Garestier T, Hélène C. Design and optimization of camptothecin conjugates of triple helix-forming oligonucleotides for sequence-specific DNA cleavage by topoisomerase I. The Journal of Biological Chemistry. 277: 3132-40. PMID 11724801 DOI: 10.1074/Jbc.M110181200 |
0.403 |
|
| 2001 |
Quada JC, Boturyn D, Hecht SM. Photoactivated DNA cleavage by compounds structurally related to the bithiazole moiety of bleomycin. Bioorganic & Medicinal Chemistry. 9: 2303-14. PMID 11553469 DOI: 10.1016/S0968-0896(01)00124-9 |
0.442 |
|
| 2001 |
Keck MV, Manderville RA, Hecht SM. Chemical and structural characterization of the interaction of bleomycin A2 with d(CGCGAATTCGCG)2. efficient, double-strand DNA cleavage accessible without structural reorganization. Journal of the American Chemical Society. 123: 8690-700. PMID 11535073 DOI: 10.1021/Ja003795I |
0.371 |
|
| 2001 |
Rishel MJ, Hecht SM. Analogues of bleomycin: synthesis of conformationally rigid methylvalerates. Organic Letters. 3: 2867-9. PMID 11529777 DOI: 10.1021/Ol010139U |
0.768 |
|
| 2001 |
Sznaidman ML, Hecht SM. Studies on the total synthesis of tallysomycin. Synthesis of the threonylbithiazole moiety containing a structurally unique glycosylcarbinolamide. Organic Letters. 3: 2811-4. PMID 11529763 DOI: 10.1021/Ol0101178 |
0.331 |
|
| 2001 |
Hashimoto S, Wang B, Hecht SM. Kinetics of DNA cleavage by Fe(II).bleomycins. Journal of the American Chemical Society. 123: 7437-8. PMID 11472181 DOI: 10.1021/Ja010558M |
0.614 |
|
| 2001 |
Abraham AT, Zhou X, Hecht SM. Metallobleomycin-mediated cleavage of DNA not involving a threading-intercalation mechanism. Journal of the American Chemical Society. 123: 5167-75. PMID 11457377 DOI: 10.1021/Ja002460Y |
0.702 |
|
| 2001 |
Krogh BO, Claeboe CD, Hecht SM, Shuman S. Effect of 2'-5' phosphodiesters on DNA transesterification by vaccinia topoisomerase. The Journal of Biological Chemistry. 276: 20907-12. PMID 11399773 DOI: 10.1074/Jbc.M102312200 |
0.406 |
|
| 2001 |
Choudhury AK, Tao ZF, Hecht SM. Synthesis and DNA cleavage activity of a novel bleomycin A(5) glycoconjugate. Organic Letters. 3: 1291-4. PMID 11348217 DOI: 10.1021/Ol010015H |
0.414 |
|
| 2001 |
Fahmi NE, Golovine S, Wang B, Hecht SM. Studies toward the site specific incorporation of sugars into proteins: synthesis of glycosylated aminoacyl-tRNAs. Carbohydrate Research. 330: 149-64. PMID 11217968 DOI: 10.1016/S0008-6215(00)00289-5 |
0.789 |
|
| 2001 |
Abraham AT, Brautigan DL, Hecht SM, Periasamy A. Localization of bleomycin in a single living cell using three-photon excitation microscopy Proceedings of Spie - the International Society For Optical Engineering. 4262: 347-353. DOI: 10.1117/12.424575 |
0.595 |
|
| 2001 |
Fahmi NE, Golovine S, Wang B, Hecht SM. ChemInform Abstract: Studies Toward the Site Specific Incorporation of Sugars into Proteins: Synthesis of Glycosylated Aminoacyl-tRNAs. Cheminform. 32: no-no. DOI: 10.1002/chin.200118193 |
0.763 |
|
| 2001 |
Lodder M, Wang B, Hecht SM. ChemInform Abstract: N-Substituted 2-Amino-4-pentenoic Acids for Amino Acid Protection and Resolution. Cheminform. 32: no-no. DOI: 10.1002/chin.200113198 |
0.54 |
|
| 2000 |
Hecht SM. Camptothecins as probes of the microenvironments of topoisomerase I--DNA complexes. Annals of the New York Academy of Sciences. 922: 76-91. PMID 11193927 DOI: 10.1111/J.1749-6632.2000.Tb07027.X |
0.37 |
|
| 2000 |
Deng JZ, Starck SR, Sun DA, Sabat M, Hecht SM. A new 7,8-euphadien-type triterpenoid from Brackenridgea nitida and Bleasdalea bleasdalei that inhibits DNA polymerase beta. Journal of Natural Products. 63: 1356-60. PMID 11076551 DOI: 10.1021/Np000129M |
0.356 |
|
| 2000 |
Leitheiser CJ, Rishel MJ, Wu X, Hecht SM. Solid-phase synthesis of bleomycin group antibiotics. Elaboration of deglycobleomycin A(5). Organic Letters. 2: 3397-9. PMID 11029220 DOI: 10.1021/Ol0002469 |
0.786 |
|
| 2000 |
Zhou BN, Hoch JM, Johnson RK, Mattern MR, Eng WK, Ma J, Hecht SM, Newman DJ, Kingston DG. Use of COMPARE analysis to discover new natural product drugs: isolation of camptothecin and 9-methoxycamptothecin from a new source. Journal of Natural Products. 63: 1273-6. PMID 11000035 DOI: 10.1021/Np000058R |
0.535 |
|
| 2000 |
Deng JZ, Newman DJ, Hecht SM. Use of COMPARE analysis to discover functional analogues of bleomycin. Journal of Natural Products. 63: 1269-72. PMID 11000034 DOI: 10.1021/Np000084P |
0.37 |
|
| 2000 |
Deng JZ, Starck SR, Hecht SM. Pentacyclic triterpenoids from Freziera sp. that inhibit DNA polymerase beta. Bioorganic & Medicinal Chemistry. 8: 247-50. PMID 10968284 DOI: 10.1016/S0968-0896(99)00276-X |
0.354 |
|
| 2000 |
Short GF, Laikhter AL, Lodder M, Shayo Y, Arslan T, Hecht SM. Probing the S1/S1' substrate binding pocket geometry of HIV-1 protease with modified aspartic acid analogues. Biochemistry. 39: 8768-81. PMID 10913288 DOI: 10.1021/Bi000214T |
0.31 |
|
| 2000 |
Starck SR, Deng JZ, Hecht SM. Naturally occurring alkylresorcinols that mediate DNA damage and inhibit its repair. Biochemistry. 39: 2413-9. PMID 10694411 DOI: 10.1021/Bi991509D |
0.423 |
|
| 2000 |
Zhou BN, Johnson RK, Mattern MR, Wang X, Hecht SM, Beck HT, Ortiz A, Kingston DG. Isolation and biochemical characterization of a new topoisomerase I inhibitor from Ocotea leucoxylon. Journal of Natural Products. 63: 217-21. PMID 10691712 DOI: 10.1021/Np990442S |
0.529 |
|
| 2000 |
Hecht SM. Bleomycin: new perspectives on the mechanism of action. Journal of Natural Products. 63: 158-68. PMID 10650103 DOI: 10.1021/Np990549F |
0.417 |
|
| 2000 |
Lodder M, Crasto CF, Laikhter AL, An H, Arslan T, Karginov VA, Short GF, Hecht SM. Synthesis of aspartic acid derivatives useful for the preparation of misacylated transfer RNAs Canadian Journal of Chemistry. 78: 884-891. DOI: 10.1139/V99-246 |
0.344 |
|
| 2000 |
Wang B, Lodder M, Zhou J, Baird TT, Brown KC, Craik CS, Hecht SM. Chemically mediated site-specific cleavage of proteins [9] Journal of the American Chemical Society. 122: 7402-7403. DOI: 10.1021/Ja0002262 |
0.644 |
|
| 2000 |
Baird T, Wang B, Lodder M, Hecht SM, Craik CS. Generation of active trypsin by chemical cleavage Tetrahedron. 56: 9477-9485. DOI: 10.1016/S0040-4020(00)00832-2 |
0.602 |
|
| 2000 |
Lodder M, Wang B, Hecht SM. N-substituted 2-amino-4-pentenoic acids for amino acid protection and resolution Tetrahedron. 56: 9421-9429. DOI: 10.1016/S0040-4020(00)00826-7 |
0.595 |
|
| 1999 |
Ma J, Starck SR, Hecht SM. DNA polymerase beta inhibitors from Tetracera boiviniana. Journal of Natural Products. 62: 1660-3. PMID 10654414 DOI: 10.1021/Np990326P |
0.365 |
|
| 1999 |
Deng JZ, Starck SR, Hecht SM. DNA polymerase beta inhibitors from Baeckea gunniana. Journal of Natural Products. 62: 1624-6. PMID 10654412 DOI: 10.1021/Np990240W |
0.345 |
|
| 1999 |
Sun DA, Starck SR, Locke EP, Hecht SM. DNA polymerase beta inhibitors from Sandoricum koetjape. Journal of Natural Products. 62: 1110-3. PMID 10479314 DOI: 10.1021/Np990104R |
0.787 |
|
| 1999 |
Deng JZ, Starck SR, Hecht SM, Ijames CF, Hemling ME. Harbinatic acid, a novel and potent DNA polymerase beta inhibitor from Hardwickia binata. Journal of Natural Products. 62: 1000-2. PMID 10425125 DOI: 10.1021/Np990099R |
0.376 |
|
| 1999 |
Short GF, Golovine SY, Hecht SM. Effects of release factor 1 on in vitro protein translation and the elaboration of proteins containing unnatural amino acids. Biochemistry. 38: 8808-19. PMID 10393557 DOI: 10.1021/Bi990281R |
0.322 |
|
| 1999 |
Wang X, Zhou X, Hecht SM. Role of the 20-hydroxyl group in camptothecin binding by the topoisomerase I-DNA binary complex. Biochemistry. 38: 4374-81. PMID 10194356 DOI: 10.1021/Bi982708K |
0.369 |
|
| 1999 |
Deng JZ, Starck SR, Hecht SM. bis-5-Alkylresorcinols from Panopsis rubescens that inhibit DNA polymerase beta. Journal of Natural Products. 62: 477-80. PMID 10096862 DOI: 10.1021/Np980522G |
0.357 |
|
| 1999 |
Deng JZ, Sun Di-An A, Starck SR, Hecht SM, Cerny RL, Engen JR. Chrysochlamic acid, a new diterpenoid-substituted quinol from Chrysochlamys ulei that inhibits DNA polymerase β Journal of the Chemical Society - Perkin Transactions 1. 1147-1149. DOI: 10.1039/A901123D |
0.344 |
|
| 1999 |
Sun D, Deng J, Starck SR, Hecht SM. Mispyric Acid, a New Monocyclic Triterpenoid with a Novel Skeleton fromMischocarpus pyriformisthat Inhibits DNA Polymerase β [J. Am. Chem. Soc.1999,121(26), 6120−6124]. Journal of the American Chemical Society. 121: 10452-10452. DOI: 10.1021/Ja995528M |
0.349 |
|
| 1999 |
Abraham AT, Zhou X, Hecht SM. DNA Cleavage by Fe(II)·Bleomycin Conjugated to a Solid SupportJ. Am. Chem. Soc.1999,121(9), 1982−1983 Journal of the American Chemical Society. 121: 4092-4092. DOI: 10.1021/Ja995504F |
0.68 |
|
| 1999 |
Aso M, Kondo M, Suemune H, Hecht SM. Chemistry of the bleomycin-induced alkali-labile DNA lesion Journal of the American Chemical Society. 121: 9023-9033. DOI: 10.1021/Ja991574A |
0.324 |
|
| 1999 |
Sun DA, Deng JZ, Starck SR, Hecht SM. Mispyric acid, a new monocyclic triterpenoid with a novel skeleton from Mischocarpus pyriformis that inhibits DNA polymerase β Journal of the American Chemical Society. 121: 6120-6124. DOI: 10.1021/Ja990208O |
0.359 |
|
| 1999 |
Abraham AT, Zhou X, Hecht SM. DNA cleavage by Fe(II)·bleomycin conjugated to a solid support [15] Journal of the American Chemical Society. 121: 1982-1983. DOI: 10.1021/Ja983774C |
0.68 |
|
| 1998 |
Lodder M, Golovine S, Laikhter AL, Karginov VA, Hecht SM. Misacylated Transfer RNAs Having a Chemically Removable Protecting Group. The Journal of Organic Chemistry. 63: 794-803. PMID 11672075 DOI: 10.1021/Jo971692L |
0.324 |
|
| 1998 |
Wang X, Short GF, Kingsbury WD, Johnson RK, Hecht SM. Effects of camptothecin analogues on DNA transformations mediated by calf thymus and human DNA topoisomerases I. Chemical Research in Toxicology. 11: 1352-60. PMID 9815197 DOI: 10.1021/Tx9801110 |
0.393 |
|
| 1998 |
Arslan T, Abraham AT, Hecht SM. Structurally altered substrates for DNA topoisomerase I. Effects of inclusion of a single 3'-deoxynucleotide within the scissile strand. Nucleosides & Nucleotides. 17: 515-30. PMID 9708360 DOI: 10.1080/07328319808005195 |
0.709 |
|
| 1998 |
Wang X, Wang LK, Kingsbury WD, Johnson RK, Hecht SM. Differential effects of camptothecin derivatives on topoisomerase I-mediated DNA structure modification. Biochemistry. 37: 9399-408. PMID 9649322 DOI: 10.1021/Bi980451K |
0.433 |
|
| 1998 |
Arslan T, Abraham AT, Hecht SM. DNA duplexes containing 3'-deoxynucleotides as substrates for DNA topoisomerase I cleavage and ligation. The Journal of Biological Chemistry. 273: 12383-90. PMID 9575192 DOI: 10.1074/Jbc.273.20.12383 |
0.715 |
|
| 1998 |
Wang X, Henningfeld KA, Hecht SM. DNA topoisomerase I-mediated formation of structurally modified DNA duplexes. Effects of metal ions and topoisomerase I inhibitors. Biochemistry. 37: 2691-700. PMID 9485420 DOI: 10.1021/Bi972707C |
0.389 |
|
| 1998 |
Quada JC, Zuber GF, Hecht SM. Interaction of bleomycin with DNA Pure and Applied Chemistry. 70: 307-311. DOI: 10.1351/Pac199870020307 |
0.389 |
|
| 1998 |
Chen J, Zhang YH, Wang LK, Sucheck SJ, Snow AM, Hecht SM. Inhibitors of DNA polymerase β from Schoepfia californica Chemical Communications. 2769-2770. DOI: 10.1039/A807053I |
0.352 |
|
| 1998 |
Katano K, An H, Aoyagi Y, Overhand M, Sucheck SJ, Stevens WC, Hess CD, Zhou X, Hecht SM. Total synthesis of bleomycin group antibiotics. Total syntheses of bleomycin demethyl A2, bleomycin A2, and decarbamoyl bleomycin demethyl A2 Journal of the American Chemical Society. 120: 11285-11296. DOI: 10.1021/Ja9819458 |
0.581 |
|
| 1998 |
Zuber G, Quada J.C. J, Hecht SM. Sequence selective cleavage of a DNA octanucleotide by chlorinated bithiazoles and bleomycins [4] Journal of the American Chemical Society. 120: 9368-9369. DOI: 10.1021/Ja981937R |
0.357 |
|
| 1998 |
Sucheck SJ, Ellena JF, Hecht SM. Characterization of Zn(II)·deglycobleomycin A2 and interaction with d(CGCTAGCG)2: Direct-evidence for minor groove binding of the bithiazole moiety Journal of the American Chemical Society. 120: 7450-7460. DOI: 10.1021/Ja9801801 |
0.303 |
|
| 1998 |
Killian JA, Van Cleve MD, Shayo YF, Hecht SM. Ribosome-Mediated Incorporation of Hydrazinophenylalanine into Modified Peptide and Protein Analogues Journal of the American Chemical Society. 120: 3032-3042. DOI: 10.1021/Ja974066E |
0.318 |
|
| 1997 |
Karginov VA, Mamaev SV, An H, Van Cleve MD, Hecht SM, Komatsoulis GA, Abelson JN. Probing the role of an active site aspartic acid in dihydrofolate reductase Journal of the American Chemical Society. 119: 8166-8176. DOI: 10.1021/Ja971099L |
0.303 |
|
| 1996 |
Wang LK, Rogers BD, Hecht SM. Inhibition of topoisomerase I function by coralyne and 5,6-dihydrocoralyne. Chemical Research in Toxicology. 9: 75-83. PMID 8924619 DOI: 10.1021/Tx950080Y |
0.412 |
|
| 1996 |
Holmes CE, Abraham AT, Hecht SM, Florentz C, Giegé R. Fe.bleomycin as a probe of RNA conformation. Nucleic Acids Research. 24: 3399-406. PMID 8811095 DOI: 10.1093/Nar/24.17.3399 |
0.671 |
|
| 1996 |
Locke EP, Hecht SM. Enantiospecific total synthesis of (+)- and (-)-avarone and -avarol Chemical Communications. 2717-2718. DOI: 10.1039/Cc9960002717 |
0.765 |
|
| 1996 |
Henningfeld KA, Arslan T, Hecht SM. Alteration of DNA Primary Structure by DNA Topoisomerase I. Isolation of the Covalent Topoisomerase I−DNA Binary Complex in Enzymatically Competent Form Journal of the American Chemical Society. 118: 11701-11714. DOI: 10.1021/Ja961788H |
0.42 |
|
| 1995 |
Kane SA, Hecht SM, Sun JS, Garestier T, Hélène C. Specific cleavage of a DNA triple helix by FeII.bleomycin. Biochemistry. 34: 16715-24. PMID 8527446 DOI: 10.1021/Bi00051A021 |
0.404 |
|
| 1995 |
Hecht SM. A model for topoisomerase i-mediated insertions and deletions with duplex DNA substrates containing branches, nicks, and gaps Biochemistry. 34: 6120-6129. PMID 7742316 DOI: 10.1021/Bi00018A015 |
0.397 |
|
| 1995 |
Hecht SM. Sequence-specific hydrolysis of yeast tRNAphe mediated by metal-free bleomycin Biochemistry. 34: 12029-12037. PMID 7547941 DOI: 10.1021/Bi00037A046 |
0.345 |
|
| 1995 |
Morgan MA, Kazakov SA, Hecht SM. Phosphoryl migration during the chemical synthesis of RNA Nucleic Acids Research. 23: 3949-3953. PMID 7479041 DOI: 10.1093/Nar/23.19.3949 |
0.324 |
|
| 1995 |
Lytollis W, Scannell RT, An H, Murty VS, Reddy KS, Barr JR, Hecht SM. 5-Alkylresorcinols from Hakea trifurcata that cleave DNA Journal of the American Chemical Society. 117: 12683-12690. DOI: 10.1021/Ja00156A004 |
0.364 |
|
| 1995 |
Kane SA, Sasaki H, Hecht SM. Guanosine-specific DNA damage by a Co(II)·bithiazole complex Journal of the American Chemical Society. 117: 9107-9118. DOI: 10.1021/Ja00141A001 |
0.391 |
|
| 1995 |
Manderville RA, Ellena JF, Hecht SM. Interaction of Zn(II)·Bleomycin with d(CGCTAGCG)2. A binding model based on NMR experiments and restrained molecular dynamics calculations Journal of the American Chemical Society. 117: 7891-7903. DOI: 10.1021/Ja00135A007 |
0.369 |
|
| 1994 |
Wang LK, Johnson RK, Hecht SM. Inhibition of topoisomerase I function by nitidine and fagaronine. Chemical Research in Toxicology. 6: 813-8. PMID 8117920 DOI: 10.1021/Tx00036A010 |
0.39 |
|
| 1994 |
Kane SA, Hecht SM. Polynucleotide recognition and degradation by bleomycin. Progress in Nucleic Acid Research and Molecular Biology. 49: 313-52. PMID 7532315 DOI: 10.1016/S0079-6603(08)60054-9 |
0.387 |
|
| 1994 |
Hecht SM. Iron(II) bleomycin-mediated degradation of a DNA-RNA heteroduplex Biochemistry®. 33: 10286-10293. PMID 7520752 DOI: 10.1021/Bi00200A008 |
0.388 |
|
| 1994 |
Overhand M, Hecht SM. A Concise Synthesis of the Antifungal Agent (+)-Preussin The Journal of Organic Chemistry. 59: 4721-4722. DOI: 10.1021/Jo00096A007 |
0.584 |
|
| 1993 |
Holmes CE, Carter BJ, Hecht SM. Characterization of iron (II).bleomycin-mediated RNA strand scission. Biochemistry. 32: 4293-307. PMID 7682845 DOI: 10.1021/Bi00067A019 |
0.318 |
|
| 1993 |
Resto E, Iida A, Van Cleve MD, Hecht SM. Amplification of protein expression in a cell free system. Nucleic Acids Research. 20: 5979-83. PMID 1281316 DOI: 10.1093/Nar/20.22.5979 |
0.37 |
|
| 1993 |
Fang SD, Wang LK, Hecht SM. Inhibitors of DNA topoisomerase I isolated from the roots of Zanthoxylum nitidum The Journal of Organic Chemistry. 58: 5025-5027. DOI: 10.1021/Jo00071A001 |
0.378 |
|
| 1993 |
Quada JC, Levy MJ, Hecht SM. Highly efficient DNA strand scission by photoactivated chlorobithiazoles Journal of the American Chemical Society. 115: 12171-12172. DOI: 10.1021/Ja00078A068 |
0.382 |
|
| 1993 |
Hecht SM, Holmes CE, Duff RJ, Morgan MA, Carter BJ, Vroom Ed, Long EC. RNA recognition and cleavage by Fe·bleomycin Journal of Inorganic Biochemistry. 51: 514. DOI: 10.1016/0162-0134(93)85540-O |
0.571 |
|
| 1992 |
Berry DE, Chan JA, MacKenzie L, Hecht SM. 9-Octadecynoic acid: a novel DNA binding agent. Chemical Research in Toxicology. 4: 195-8. PMID 1664257 DOI: 10.1021/Tx00020A011 |
0.401 |
|
| 1992 |
Hecht SM, Berry DE, MacKenzie LJ, Busby RW, Nasuti CA. A strategy for identifying novel, mechanistically unique inhibitors of topoisomerase I. Journal of Natural Products. 55: 401-13. PMID 1324981 DOI: 10.1021/Np50082A001 |
0.325 |
|
| 1992 |
Berry DE, MacKenzie L, Shultis EA, Chan JA, Hecht SM. Naturally occurring inhibitors of topoisomerase I mediated DNA relaxation The Journal of Organic Chemistry. 57: 420-422. DOI: 10.1021/Jo00028A002 |
0.371 |
|
| 1992 |
Hamamichi N, Natrajan A, Hecht SM. On the role of individual bleomycin thiazoles in oxygen activation and DNA cleavage Journal of the American Chemical Society. 114: 6278-6291. DOI: 10.1021/Ja00042A002 |
0.406 |
|
| 1991 |
Kingsbury WD, Boehm JC, Jakas DR, Holden KG, Hecht SM, Gallagher G, Caranfa MJ, McCabe FL, Faucette LF, Johnson RK, Hertzberg RP. Synthesis of water-soluble (aminoalkyl)camptothecin analogues: Inhibition of topoisomerase I and antitumor activity Journal of Medicinal Chemistry. 34: 98-107. PMID 1846923 DOI: 10.1021/Jm00105A017 |
0.357 |
|
| 1990 |
Dange V, Van Atta RB, Hecht SM. A Mn2(+)-dependent ribozyme. Science (New York, N.Y.). 248: 585-8. PMID 2185542 DOI: 10.1126/Science.2185542 |
0.302 |
|
| 1990 |
Carter BJ, De Vroom E, Long EC, Van Der Marel GA, Van Boom JH, Hecht SM. Site-specific cleavage of RNA by Fe(II)·bleomycin Proceedings of the National Academy of Sciences of the United States of America. 87: 9373-9377. PMID 1701259 DOI: 10.1073/Pnas.87.23.9373 |
0.61 |
|
| 1990 |
Hecht SM. On the chemical nature of DNA and RNA modification by a hemin model system Biochemistry®. 29: 4783-4789. PMID 1694683 DOI: 10.1021/Bi00472A006 |
0.39 |
|
| 1990 |
Aoyagi Y, Chorghade MS, Padmapriya AA, Suguna H, Hecht SM. Synthesis of pyrimidoblamic acid and epipyrimidoblamic acid The Journal of Organic Chemistry. 55: 6291-6298. DOI: 10.1021/Jo00313A016 |
0.336 |
|
| 1990 |
Long EC, Hecht SM, Van der Marel GA, Van Boom JH. Interaction of bleomycin with a methylated DNA oligonucleotide Journal of the American Chemical Society. 112: 5272-5276. DOI: 10.1021/Ja00169A040 |
0.633 |
|
| 1989 |
Roesser JR, Xu C, Payne RC, Surratt CK, Hecht SM. Preparation of misacylated aminoacyl-tRNA(Phe)'s useful as probes of the ribosomal acceptor site. Biochemistry. 28: 5185-95. PMID 2569893 DOI: 10.1021/Bi00438A041 |
0.303 |
|
| 1989 |
Hertzberg RP, Caranfa MJ, Hecht SM. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. Biochemistry. 28: 4629-38. PMID 2548584 DOI: 10.1021/Bi00437A018 |
0.424 |
|
| 1989 |
Hecht SM. Natural products that cleave DNA Pure and Applied Chemistry. 61: 577-580. DOI: 10.1351/Pac198961030577 |
0.398 |
|
| 1989 |
Van Atta RB, Long EC, Hecht SM, Van der Marel GA, Van Boom JH. Electrochemical activation of oxygenated iron-bleomycin Journal of the American Chemical Society. 111: 2722-2724. DOI: 10.1021/Ja00189A061 |
0.556 |
|
| 1989 |
Saito I, Morii T, Sugiyama H, Matsuura T, Meares CF, Hecht SM. Photoinduced DNA strand scission by cobalt bleomycin green complex Journal of the American Chemical Society. 111: 2307-2308. DOI: 10.1021/Ja00188A057 |
0.365 |
|
| 1988 |
Jäger A, Levy MJ, Hecht SM. Oligonucleotide N-alkylphosphoramidates: synthesis and binding to polynucleotides. Biochemistry. 27: 7237-46. PMID 3264723 DOI: 10.1021/Bi00419A010 |
0.316 |
|
| 1988 |
Barr JR, Murty VS, Yamaguchi K, Singh S, Smith DH, Hecht SM. 5-Alkylresorcinols from Hakea amplexicaulis that cleave DNA Chemical Research in Toxicology. 1: 204-207. PMID 2980968 DOI: 10.1021/Tx00004A003 |
0.389 |
|
| 1988 |
Shipley JB, Hecht SM. Bleomycin congeners exhibiting altered DNA cleavage specificity. Chemical Research in Toxicology. 1: 25-7. PMID 2485129 DOI: 10.1021/Tx00001A004 |
0.391 |
|
| 1988 |
Levy MJ, Hecht SM. Copper(II) facilitates bleomycin-mediated unwinding of plasmid DNA. Biochemistry. 27: 2647-50. PMID 2456777 DOI: 10.1021/Bi00408A002 |
0.355 |
|
| 1988 |
Hertzberg RP, Caranfa MJ, Hecht SM. Degradation of structurally modified DNAs by bleomycin group antibiotics. Biochemistry. 27: 3164-74. PMID 2455539 DOI: 10.1021/Bi00409A007 |
0.409 |
|
| 1988 |
Sugiyama H, Xu C, Murugesan N, Hecht SM, van der Marel GA, van Boom JH. Chemistry of the alkali-labile lesion formed from iron(II) bleomycin and d(CGCTTTAAAGCG). Biochemistry. 27: 58-67. PMID 2450572 DOI: 10.1021/Bi00401A011 |
0.328 |
|
| 1988 |
Scannell RT, Barr JR, Murty VS, Reddy KS, Hecht SM. DNA strand scission by naturally occurring 5-alkylresorcinols Journal of the American Chemical Society. 110: 3650-3651. DOI: 10.1021/Ja00219A046 |
0.38 |
|
| 1988 |
Gold B, Dange V, Moore MA, Eastman A, Van der Marel GA, Van Boom JH, Hecht SM. Alteration of bleomycin cleavage specificity in a platinated DNA oligomer of defined structure Journal of the American Chemical Society. 110: 2347-2349. DOI: 10.1021/Ja00215A080 |
0.384 |
|
| 1988 |
Chrisey LA, Shahidi Bonjar GH, Hecht SM. DNA strand scission by (-)-epicatechin and procyanidin B2 Journal of the American Chemical Society. 110: 644-646. DOI: 10.1021/Ja00210A080 |
0.348 |
|
| 1988 |
Long EC, Hecht SM. Direct comparison of oxygen transfer by iron bleomycin and zinc bleomycin Tetrahedron Letters. 29: 6413-6416. DOI: 10.1016/S0040-4039(00)82360-6 |
0.573 |
|
| 1987 |
Roesser JR, Chorghade MS, Hecht SM. Ribosome-catalyzed formation of an abnormal peptide analogue. Biochemistry. 25: 6361-5. PMID 3539188 DOI: 10.1021/Bi00369A003 |
0.304 |
|
| 1987 |
Ehrenfeld GM, Shipley JB, Heimbrook DC, Sugiyama H, Long EC, Van Boom JH, Van Der Marel GA, Oppenheimer NJ, Hecht SM. Copper-dependent cleavage of DNA by bleomycin Biochemistry. 26: 931-942. PMID 2436656 DOI: 10.1021/Bi00377A038 |
0.607 |
|
| 1987 |
Heimbrook DC, Carr SA, Mentzer MA, Long EC, Hecht SM. Mechanism of oxygenation of cis-stilbene by iron bleomycin Inorganic Chemistry. 26: 3835-3836. DOI: 10.1021/Ic00270A003 |
0.547 |
|
| 1986 |
Hertzberg RP, Caranfa MJ, Hecht SM. DNA methylation diminishes bleomycin-mediated strand scission. Biochemistry. 24: 5286-9. PMID 2416341 DOI: 10.1021/Bi00341A001 |
0.409 |
|
| 1986 |
Hecht SM. The chemistry of activated bleomycin Accounts of Chemical Research. 19: 395-402. DOI: 10.1007/978-94-009-0397-5_16 |
0.376 |
|
| 1986 |
Sugiyama H, Kilkuskie RE, Chang LH, Ma LT, Hecht SM, Van der Marel GA, Van Boom JH. DNA strand scission by bleomycin: catalytic cleavage and strand selectivity Journal of the American Chemical Society. 108: 3852-3854. DOI: 10.1002/Chin.198643307 |
0.391 |
|
| 1985 |
Sugiyama H, Ehrenfeld GM, Shipley JB, Kilkuskie RE, Chang LH, Hecht SM. DNA strand scission by bleomycin group antibiotics. Journal of Natural Products. 48: 869-77. PMID 2419510 DOI: 10.1021/Np50042A001 |
0.358 |
|
| 1985 |
Murugesan N, Xu C, Ehrenfeld GM, Sugiyama H, Kilkuskie RE, Rodriguez LO, Chang LH, Hecht SM. Analysis of products formed during bleomycin-mediated DNA degradation. Biochemistry. 24: 5735-44. PMID 2417619 DOI: 10.1021/Bi00342A008 |
0.394 |
|
| 1985 |
Berry DE, Kilkuskie RE, Hecht SM. DNA damage induced by bleomycin in the presence of dibucaine is not predictive of cell growth inhibition. Biochemistry. 24: 3214-9. PMID 2411289 DOI: 10.1021/Bi00334A021 |
0.366 |
|
| 1985 |
Berry DE, Chang LH, Hecht SM. DNA damage and growth inhibition in cultured human cells by bleomycin congeners. Biochemistry. 24: 3207-14. PMID 2411288 DOI: 10.1021/Bi00334A020 |
0.357 |
|
| 1985 |
Sugiyama H, Xu C, Murugesan N, Hecht SM. Structure of the alkali-labile product formed during iron(II)-bleomycin-mediated DNA strand scission Journal of the American Chemical Society. 107: 4104-4105. DOI: 10.1021/Ja00299A072 |
0.339 |
|
| 1985 |
Sugiyama H, Kilkuskie RE, Hecht SM, Van der Marel GA, Van Boom JH. An efficient, site-specific DNA target for bleomycin Journal of the American Chemical Society. 107: 7765-7767. DOI: 10.1002/Chin.198613102 |
0.359 |
|
| 1985 |
SUGIYAMA H, XU C, MURUGESAN N, HECHT SM. ChemInform Abstract: STRUCTURE OF THE ALKALI-LABILE PRODUCT FORMED DURING IRON(II)-BLEOMYCIN-MEDIATED DNA STRAND SCISSION Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198543352 |
0.344 |
|
| 1985 |
Kilkuskie RE, Suguna H, Yellin B, Murugesan N, Hecht SM. Oxygen transfer by bleomycin analogs dysfunctional in DNA cleavage Journal of the American Chemical Society. 107: 260-261. DOI: 10.1002/Chin.198519337 |
0.345 |
|
| 1984 |
Heckler TG, Chang LH, Zama Y, Naka T, Chorghade MS, Hecht SM. T4 RNA ligase mediated preparation of novel "chemically misacylated" tRNAPheS. Biochemistry. 23: 1468-73. PMID 6372858 DOI: 10.1021/Bi00302A020 |
0.302 |
|
| 1984 |
Kilkuskie RE, Macdonald TL, Hecht SM. Bleomycin may be activated for DNA cleavage by NADPH-cytochrome P-450 reductase. Biochemistry. 23: 6165-71. PMID 6084519 DOI: 10.1021/Bi00320A042 |
0.346 |
|
| 1984 |
Heckler TG, Chang LH, Zama Y, Naka T, Hecht SM. Preparation of '2,('3)-O-Acyl-pCpA derivatives as substrates for T4 RNA ligase-mediated "chemical aminoacylation" Tetrahedron. 40: 87-94. DOI: 10.1016/0040-4020(84)85106-6 |
0.315 |
|
| 1984 |
Ehrenfeld GM, Murugesan N, Hecht SM. Activation of oxygen and mediation of DNA degradation by manganese-bleomycin Inorganic Chemistry. 23: 1496-1498. DOI: 10.1002/Chin.198435135 |
0.35 |
|
| 1982 |
Kross J, Henner WD, Hecht SM, Haseltine WA. Specificity of deoxyribonucleic acid cleavage by bleomycin, phleomycin, and tallysomycin. Biochemistry. 21: 4310-8. PMID 6181807 DOI: 10.1021/Bi00261A021 |
0.371 |
|
| 1982 |
Kross J, Henner WD, Haseltine WA, Rodriguez L, Levin MD, Hecht SM. Structural basis for the deoxyribonucleic acid affinity of bleomycins. Biochemistry. 21: 3711-21. PMID 6180763 DOI: 10.1021/bi00258a029 |
0.306 |
|
| 1982 |
Rodriguez LO, Hecht SM. Iron(II)-bleomycin. Biochemical and spectral properties in the presence of radical scavengers. Biochemical and Biophysical Research Communications. 104: 1470-6. PMID 6176244 DOI: 10.1016/0006-291X(82)91416-4 |
0.305 |
|
| 1982 |
Aoyagi Y, Katano K, Suguna H, Primeau J, Chang LH, Hecht SM. Total synthesis of bleomycin Journal of the American Chemical Society. 104: 5537-5538. DOI: 10.1021/Ja00384A067 |
0.305 |
|
| 1981 |
Pozsgay V, Ohgi T, Hecht SM. Synthesis of the carbohydrate moiety of bleomycin The Journal of Organic Chemistry. 46: 3761-3763. DOI: 10.1002/Chin.198205345 |
0.328 |
|
| 1980 |
Pezzuto JM, Lau PP, Luh Y, Moore PD, Wogan GN, Hecht SM. There is a correlation between the DNA affinity and mutagenicity of several 3-amino-1-methyl-5H-pyrido[4,3-b]indoles Proceedings of the National Academy of Sciences of the United States of America. 77: 1427-1431. PMID 6990411 DOI: 10.1073/Pnas.77.3.1427 |
0.391 |
|
| 1980 |
Oppenheimer NJ, Rodriguez LO, Hecht SM. Metal binding to modified bleomycins. Zinc and ferrous complexes with an acetylated bleomycin. Biochemistry. 19: 4096-103. PMID 6157406 DOI: 10.1021/Bi00558A030 |
0.36 |
|
| 1980 |
Arai H, Hagmann WK, Suguna H, Hecht SM. Synthesis of the pyrimidine moieties of bleomycin and epi-bleomycin Journal of the American Chemical Society. 102: 6631-6633. DOI: 10.1002/Chin.198103318 |
0.341 |
|
| 1979 |
Alford BL, Chinault AC, Jolly SO, Hecht SM. Preparation of tRNAs terminating in 2'- and 3'- deoxyadenosine. Methods in Enzymology. 59: 121-34. PMID 374934 DOI: 10.1016/0076-6879(79)59074-0 |
0.309 |
|
| 1979 |
Evans DL, Minster DK, Jordis U, Hecht SM, Mazzu AL, Meyers AI. Nickel peroxide dehydrogenation of oxygen-, sulfur-, and nitrogen-containing heterocycles The Journal of Organic Chemistry. 44: 497-501. DOI: 10.1002/Chin.197926149 |
0.677 |
|
| 1979 |
EVANS DL, MINSTER DK, JORDIS U, HECHT SM, MAZZU ALJ, MEYERS AI. ChemInform Abstract: NICKEL PEROXIDE DEHYDROGENATION OF OXYGEN-, SULFUR-, AND NITROGEN-CONTAINING HETEROCYCLES Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197926149 |
0.68 |
|
| 1978 |
Minster D, Jordis U, Evans D, Hecht S. Correction. Thiazoles from Cysteinyl Peptides The Journal of Organic Chemistry. 43: 5027-5027. DOI: 10.1021/Jo00420A619 |
0.687 |
|
| 1978 |
MINSTER DK, JORDIS U, EVANS DL, HECHT SM. ChemInform Abstract: THIAZOLES FROM CYSTEINYL PEPTIDES Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197834249 |
0.671 |
|
| 1978 |
Minster DK, Jordis U, Evans DL, Hecht SM. Thiazoles from cysteinyl peptides The Journal of Organic Chemistry. 43: 1624-1626. DOI: 10.1002/Chin.197834249 |
0.687 |
|
| 1978 |
MCGOWAN DA, JORDIS U, MINSTER DK, HECHT SM. ChemInform Abstract: A BIOMIMETIC SYNTHESIS OF THE BITHIAZOLE MOIETY OF BLEOMYCIN Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197810223 |
0.718 |
|
| 1977 |
Chinault AC, Kozarich JW, Hecht SM, Schmidt FJ, Bock RM. Preparation of Escherichia coli tRNAs terminating in modified nucleosides by the use of CTP(ATP):tRNA nucleotidyltransferase and polynucleotide phosphorylase Biochemistry. 16: 756-765. PMID 319825 DOI: 10.1021/Bi00623A030 |
0.528 |
|
| 1977 |
McGowan DA, Jordis U, Minster DK, Hecht SM. A biomimetic synthesis of the bithiazole moiety of bleomycin Journal of the American Chemical Society. 99: 8078-8079. DOI: 10.1002/Chin.197810223 |
0.737 |
|
| 1976 |
Hecht SM, Adams BL, Kozarich JW. Chemical transformations of 7,9-disubstituted purines and related heterocycles. Selective reduction of imines and immonium salts. The Journal of Organic Chemistry. 41: 2303-11. PMID 6641 DOI: 10.1021/Jo00875A019 |
0.492 |
|
| 1976 |
HECHT SM, ADAMS BL, KOZARICH JW. ChemInform Abstract: CHEMICAL TRANSFORMATIONS OF 7,9-DISUBSTITUTED PURINES AND RELATED HETEROCYCLES. SELECTIVE REDUCTION OF IMINES AND IMMONIUM SALTS Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197642295 |
0.499 |
|
| 1975 |
Kozarich JW, Chinault AC, Hecht SM. Ribonucleoside 3'-di- and -triphosphates. Synthesis of guanosine tetraphosphate (ppGpp). Biochemistry. 14: 981-8. PMID 235948 DOI: 10.1021/Bi00676A017 |
0.518 |
|
| 1974 |
Hecht SM, Kozarich JW. A chemical synthesis of adenosine 5'-(gamma-32P)triphosphate. Biochimica Et Biophysica Acta. 331: 307-9. PMID 4777661 DOI: 10.1016/0005-2787(73)90015-4 |
0.523 |
|
| 1974 |
Hecht SM, Kozarich JW, Schmidt FJ. Isomeric phenylalanyl tRNAs. Position of the aminoacyl moiety during protein biosynthesis Proceedings of the National Academy of Sciences of the United States of America. 71: 4317-4321. PMID 4612516 DOI: 10.1073/Pnas.71.11.4317 |
0.545 |
|
| 1974 |
Kozarich JW, Chinault AC, Hecht SM. Ribonucleoside phosphates via phosphorimidazolidate intermediates. Synthesis of pseudoadenosine 5'-triphosphate. Biochemistry. 12: 4458-63. PMID 4584326 DOI: 10.1021/Bi00746A024 |
0.535 |
|
| 1974 |
Hecht SM, Faulkner RD, Hawrelak SD. Competitive inhibition of beef heart cyclic AMP phosphodiesterase by cytokinins and related compounds Proceedings of the National Academy of Sciences of the United States of America. 71: 4670-4674. PMID 4373727 DOI: 10.1073/Pnas.71.12.4670 |
0.311 |
|
| 1973 |
Hecht SM, Hawrelak SD, Kozarich JW, Schmidt FJ, Bock RM. Chemical modifications of transfer RNA species. Transfer RNA's terminating in 2′- and 3′-O-methyladenosine Biochemical and Biophysical Research Communications. 52: 1341-1347. PMID 4577827 DOI: 10.1016/0006-291X(73)90648-7 |
0.516 |
|
| 1973 |
Hecht SM, Kozarich JW. Mechanism of the base-induced decomposition of N-nitroso-N-methylurea The Journal of Organic Chemistry. 38: 1821-1824. DOI: 10.1021/Jo00950A011 |
0.455 |
|
| 1973 |
Hecht SM, Kozarich JW. generation of diazomethane Tetrahedron Letters. 14: 1397-1400. DOI: 10.1016/S0040-4039(01)95953-2 |
0.453 |
|
| 1973 |
HECHT SM, KOZARICH JW. ChemInform Abstract: DEMETHYLATION OF 7-METHYLGUANOSINE WITH LITHIUM 2-METHYLPROPANE-2-THIOLATE Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197337165 |
0.481 |
|
| 1972 |
Schmitz RY, Skoog F, Hecht SM, Leonard NJ. Comparison of Zeatin Indoleacetate with Zeatin and Indoleacetic Acid in the Tobacco Bioassay Plant Physiology. 50: 114-116. PMID 16658104 DOI: 10.1104/Pp.50.1.114 |
0.57 |
|
| 1972 |
Hecht S, Bock R, Schmitz R, Skoog F, Leonard N, Occolowitz J. Corrections - Question of the Ribosyl Moiety in the Promotion of Callus Growth by Exogenously Added Cytokinins Biochemistry. 11: 1122-1122. DOI: 10.1021/Bi00756A603 |
0.535 |
|
| 1972 |
Hecht SM, Kozarich JW. The base-induced decomposition of N-nitroso-N-methylurea Tetrahedron Letters. 13: 5147-5150. DOI: 10.1016/S0040-4039(01)85192-3 |
0.454 |
|
| 1972 |
Hecht SM, Kozarich JW. A convenient method for the production of diazomethane-2 Tetrahedron Letters. 13: 1501-1502. DOI: 10.1016/S0040-4039(01)84667-0 |
0.454 |
|
| 1972 |
Schmitz RY, Skoog F, Hecht SM, Bock RM, Leonard NJ. Comparison of cytokinin activities of naturally occurring ribonucleosides and corresponding bases Phytochemistry. 11: 1603-1610. DOI: 10.1016/0031-9422(72)85006-4 |
0.541 |
|
| 1971 |
Hecht SM, Bock RM, Schmitz RY, Skoog F, Leonard NJ. Cytokinins: development of a potent antagonist. Proceedings of the National Academy of Sciences of the United States of America. 68: 2608-10. PMID 5289891 DOI: 10.1073/Pnas.68.10.2608 |
0.581 |
|
| 1971 |
Hecht SM, Bock RM, Schmitz RY, Skoog F, Leonard NJ, Occolowitz JL. Question of the ribosyl moiety in the promotion of callus growth by exogenously added cytokinins. Biochemistry. 10: 4224-8. PMID 5126937 DOI: 10.1021/Bi00799A011 |
0.485 |
|
| 1971 |
Hecht SM, Kirkegaard LH, Bock RM. Chemical modifications of transfer RNA species. Desulfurization with Raney nickel. Proceedings of the National Academy of Sciences of the United States of America. 68: 48-51. PMID 4924970 DOI: 10.1073/Pnas.68.1.48 |
0.332 |
|
| 1971 |
Schmitz RY, Skoog F, Hecht SM, Leonard NJ. Cytokinins: Synthesis and biological activity of zeatin esters and related compounds Phytochemistry. 10: 275-280. DOI: 10.1016/S0031-9422(00)94040-8 |
0.603 |
|
| 1971 |
SCHMITZ RY, SKOOG F, HECHT SM, LEONARD NJ. ChemInform Abstract: CYTOKININE, SYNTH. UND BIOLOGISCHE AKTIVITAET VON ZEATINESTERN UND VERWANDTEN VERBINDUNGEN Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197121268 |
0.491 |
|
| 1970 |
Hecht SM, Bock RM, Leonard NJ, Schmitz RY. Cytokinin activity in tRNA-Phe. Biochemical and Biophysical Research Communications. 41: 435-40. PMID 5518173 DOI: 10.1016/0006-291X(70)90523-1 |
0.555 |
|
| 1970 |
Hecht SM, Gupta AS, Leonard NJ. Mass spectra of ribonucleoside components of tRNA. II. Analytical Biochemistry. 38: 230-51. PMID 5478243 DOI: 10.1016/0003-2697(70)90173-9 |
0.569 |
|
| 1970 |
Burrows WJ, Armstrong DJ, Kaminek M, Skoog F, Bock RM, Hecht SM, Dammann LG, Leonard NJ, Occolowitz J. Isolation and identification of four cytokinins from wheat germ transfer ribonucleic acid. Biochemistry. 9: 1867-72. PMID 5442155 DOI: 10.1021/bi00811a001 |
0.503 |
|
| 1970 |
Armstrong DJ, Evans PK, Burrows WJ, Skoog F, Petit JF, Dahl JL, Steward T, Strominger JL, Leonard NJ, Hecht SM, Occolowitz J. Cytokinins. Activity and identification in Staphylococcus epidermidis transfer ribonucleic acid. The Journal of Biological Chemistry. 245: 2922-6. PMID 5423380 |
0.514 |
|
| 1970 |
Hecht SM, Leonard NJ, Schmitz RY, Skoog F. Cytokinins: Influence of side-chain planarity of N6-substituted adenines and adenosines on their activity in promoting cell growth Phytochemistry. 9: 1907-1913. DOI: 10.1016/S0031-9422(00)85338-8 |
0.593 |
|
| 1970 |
Hecht SM, Leonard NJ, Schmitz RY, Skoog F. Cytokinins: Synthesis and growth-promoting activity of 2-substituted compounds in the N6-isopentenyladenine and zeatin series Phytochemistry. 9: 1173-1180. DOI: 10.1016/S0031-9422(00)85305-4 |
0.605 |
|
| 1970 |
HECHT SM, LEONARD NJ, SCHMITZ RY, SKOOG F. ChemInform Abstract: CYTOKININE, SYNTH. UND WACHSTUMSBESCHLEUNIGENDE AKTIVITAET VON 2-SUBSTITUIERTEN VERBINDUNGEN IN DER N(6)-ISOPENTENYLADENIN- UND ZEATINREIHE Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197036414 |
0.486 |
|
| 1969 |
Leonard NJ, Hecht SM, Skoog F, Schmitz RY. Cytokinins: synthesis, mass spectra, and biological activity of compounds related to zeatin. Proceedings of the National Academy of Sciences of the United States of America. 63: 175-82. PMID 16591745 DOI: 10.1073/Pnas.63.1.175 |
0.609 |
|
| 1969 |
Hecht SM, Gupta AS, Leonard NJ. Mass spectra of nucleoside components of tRNA. Analytical Biochemistry. 30: 249-70. PMID 5809667 DOI: 10.1016/0003-2697(69)90396-0 |
0.554 |
|
| 1969 |
Hecht SM, Gupta AS, Leonard NJ. Position of uridine thiation: the identification of minor nucleosides from transfer RNA by mass spectrometry. Biochimica Et Biophysica Acta. 182: 444-8. PMID 5795488 DOI: 10.1016/0005-2787(69)90195-6 |
0.591 |
|
| 1969 |
Hecht SM, Leonard NJ. , Occolowitz J, Burrows WJ, Armstrong DJ, Skoog F, Bock RM, Gillam I, Tener GM: Cytokinins: isolation identification of 6-(3-methyl-2-butenylamino)-9-beta-D-ribyfuranosylpurine (2iPA) from yeast cysteine tRNA. Biochemical and Biophysical Research Communications. 35: 205-9. PMID 5772580 DOI: 10.1016/0006-291X(69)90268-X |
0.572 |
|
| 1969 |
Hecht SM, Leonard NJ, Burrows WJ, Armstrong DJ, Skoog F, Occolowitz J. Cytokinin of wheat germ transfer RNA: 6-(4-hydroxy-3-methyl-2-butenylamino)-2-methylthio-9-beta-D-ribofuranosylpurine. Science (New York, N.Y.). 166: 1272-4. PMID 5350318 DOI: 10.1126/Science.166.3910.1272 |
0.589 |
|
| 1969 |
Burrows WJ, Armstrong DJ, Skoog F, Hecht SM, Boyle JT, Leonard NJ, Occolowitz J. The isolation and identification of two cytokinins from Escherichia coli transfer ribonucleic acids. Biochemistry. 8: 3071-6. PMID 4897210 DOI: 10.1021/Bi00835A057 |
0.555 |
|
| 1968 |
Leonard NJ, Hecht SM, Skoog F, Schmitz RY. CYTOKININS: SYNTHESIS OF 6-(3-METHYL-3-BUTENYLAMINO)-9-beta-D-RIBOFURANOSYLPURINE (3IPA), AND THE EFFECT OF SIDE-CHAIN UNSATURATION ON THE BIOLOGICAL ACTIVITY OF ISOPENTYLAMINOPURINES AND THEIR RIBOSIDES. Proceedings of the National Academy of Sciences of the United States of America. 59: 15-21. PMID 16591586 DOI: 10.1073/Pnas.59.1.15 |
0.604 |
|
| 1968 |
Burrows WJ, Armstrong DJ, Skoog F, Hecht SM, Boyle JT, Leonard NJ, Occolowitz J. Cytokinin from soluble RNA of Escherichia coli: 6-(3-methyl-2-butenylamino)-2-methylthio-9-beta-D-ribofuranosylpurine. Science (New York, N.Y.). 161: 691-3. PMID 4874577 DOI: 10.1126/Science.161.3842.691 |
0.598 |
|
| 1968 |
Leonard NJ, Hecht SM, Skoog F, Schmitz RY. Cytokinins: Synthesis and Biological Activity of Related Derivatives of 2iP, 3iP, and their Ribosides Israel Journal of Chemistry. 6: 539-550. DOI: 10.1002/Ijch.196800073 |
0.601 |
|
| 1967 |
Leonard NJ, Hecht SM. 6-(3-Methylbut-3-enylamino)pyrine: a highly active cytokinin Chemical Communications (London). DOI: 10.1039/C1967000973A |
0.554 |
|
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