| Year |
Citation |
Score |
| 2013 |
Omene C, Kalac M, Wu J, Marchi E, Frenkel K, O'Connor OA. Propolis and its Active Component, Caffeic Acid Phenethyl Ester (CAPE), Modulate Breast Cancer Therapeutic Targets via an Epigenetically Mediated Mechanism of Action. Journal of Cancer Science & Therapy. 5: 334-342. PMID 24466386 DOI: 10.4172/1948-5956.1000224 |
0.371 |
|
| 2012 |
Wu J, Sowinska A, Huang X, Klein CB, Pelle E, Frenkel K. Impairment of antioxidant defenses as a contributor to arsenite-induced cell transformation. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 25: 927-37. PMID 22692362 DOI: 10.1007/S10534-012-9559-1 |
0.405 |
|
| 2012 |
Omene CO, Wu J, Frenkel K. Caffeic Acid Phenethyl Ester (CAPE) derived from propolis, a honeybee product, inhibits growth of breast cancer stem cells. Investigational New Drugs. 30: 1279-88. PMID 21537887 DOI: 10.1007/S10637-011-9667-8 |
0.383 |
|
| 2011 |
Wu J, Omene C, Karkoszka J, Bosland M, Eckard J, Klein CB, Frenkel K. Caffeic acid phenethyl ester (CAPE), derived from a honeybee product propolis, exhibits a diversity of anti-tumor effects in pre-clinical models of human breast cancer. Cancer Letters. 308: 43-53. PMID 21570765 DOI: 10.1016/J.Canlet.2011.04.012 |
0.734 |
|
| 2011 |
Omene CO, Wu J, Qu S, Smith J, Frenkel K. Abstract 3344: CAPE-induced inhibition of breast cancer stem cells (CSC) self-renewal and growth by differentiation to a less malignant phenotype Cancer Research. 71: 3344-3344. DOI: 10.1158/1538-7445.Am2011-3344 |
0.386 |
|
| 2010 |
Yusuf R, Frenkel K. Morphologic transformation of human breast epithelial cells MCF-10A: dependence on an oxidative microenvironment and estrogen/epidermal growth factor receptors. Cancer Cell International. 10: 30. PMID 20809984 DOI: 10.1186/1475-2867-10-30 |
0.659 |
|
| 2010 |
Eckard J, Dai J, Wu J, Jian J, Yang Q, Chen H, Costa M, Frenkel K, Huang X. Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis. Iron deficiency and angiogenesis. Cancer Cell International. 10: 28. PMID 20723262 DOI: 10.1186/1475-2867-10-28 |
0.717 |
|
| 2010 |
Wu J, Omene C, Smith J, Frenkel K. Abstract 3555: Inhibition of breast cancer stem cells (CSC) self-renewal and growth by CAPE, a product of propolis Cancer Research. 70: 3555-3555. DOI: 10.1158/1538-7445.Am10-3555 |
0.402 |
|
| 2010 |
Omene C, Wu J, Kalac M, O'Connor O, Frenkel K. Abstract P6-14-07: Epigenetic Pharmacomodulation of Therapeutic Targets in Breast Cancer with a Naturopathic Formulation of Propolis, a Honeybee Product Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P6-14-07 |
0.388 |
|
| 2008 |
Dai J, Jian J, Bosland M, Frenkel K, Bernhardt G, Huang X. Roles of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status. Breast (Edinburgh, Scotland). 17: 172-9. PMID 17928227 DOI: 10.1016/J.Breast.2007.08.009 |
0.356 |
|
| 2007 |
Burns FJ, Tang MS, Frenkel K, Nádas A, Wu F, Uddin A, Zhang R. Induction and prevention of carcinogenesis in rat skin exposed to space radiation. Radiation and Environmental Biophysics. 46: 195-9. PMID 17387500 DOI: 10.1007/S00411-007-0106-3 |
0.305 |
|
| 2006 |
Wu J, Eckard J, Chen H, Costa M, Frenkel K, Huang X. Altered iron homeostasis involvement in arsenite-mediated cell transformation. Free Radical Biology & Medicine. 40: 444-52. PMID 16443159 DOI: 10.1016/J.Freeradbiomed.2005.08.035 |
0.731 |
|
| 2005 |
Yang C, Wu J, Zhang R, Zhang P, Eckard J, Yusuf R, Huang X, Rossman TG, Frenkel K. Caffeic acid phenethyl ester (CAPE) prevents transformation of human cells by arsenite (As) and suppresses growth of As-transformed cells. Toxicology. 213: 81-96. PMID 16085347 DOI: 10.1016/J.Tox.2005.05.011 |
0.709 |
|
| 2004 |
Dai J, Huang C, Wu J, Yang C, Frenkel K, Huang X. Iron-induced interleukin-6 gene expression: possible mediation through the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways. Toxicology. 203: 199-209. PMID 15363595 DOI: 10.1016/J.Tox.2004.06.009 |
0.376 |
|
| 2003 |
Pelle E, Huang X, Mammone T, Marenus K, Maes D, Frenkel K. Ultraviolet-B-induced oxidative DNA base damage in primary normal human epidermal keratinocytes and inhibition by a hydroxyl radical scavenger. The Journal of Investigative Dermatology. 121: 177-83. PMID 12839579 DOI: 10.1046/J.1523-1747.2003.12330.X |
0.35 |
|
| 2002 |
Yang C, Frenkel K. Arsenic-mediated cellular signal transduction, transcription factor activation, and aberrant gene expression: implications in carcinogenesis. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 21: 331-42. PMID 12510962 DOI: 10.1615/Jenvironpatholtoxicoloncol.V21.I4.20 |
0.34 |
|
| 2002 |
Li X, Eckard J, Shah R, Malluck C, Frenkel K. Interleukin-1alpha up-regulation in vivo by a potent carcinogen 7,12-dimethylbenz(a)anthracene (DMBA) and control of DMBA-induced inflammatory responses. Cancer Research. 62: 417-23. PMID 11809690 |
0.715 |
|
| 2002 |
Huang X, Dai J, Fournier J, Ali AM, Zhang Q, Frenkel K. Ferrous ion autoxidation and its chelation in iron-loaded human liver HepG2 cells. Free Radical Biology & Medicine. 32: 84-92. PMID 11755320 DOI: 10.1016/S0891-5849(01)00770-5 |
0.336 |
|
| 1997 |
Huang MT, Ma W, Yen P, Xie JG, Han J, Frenkel K, Grunberger D, Conney AH. Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis. Carcinogenesis. 18: 83-8. PMID 9054592 DOI: 10.1093/Carcin/18.1.83 |
0.367 |
|
| 1997 |
Huang M, Newmark HL, Frenkel K. Inhibitory effects of curcumin on tumorigenesis in mice Journal of Cellular Biochemistry. 67: 26-34. DOI: 10.1002/(Sici)1097-4644(1997)27+<26::Aid-Jcb7>3.0.Co;2-3 |
0.403 |
|
| 1996 |
Huang MT, Ma W, Yen P, Xie JG, Han J, Frenkel K, Grunberger D, Conney AH. Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells. Carcinogenesis. 17: 761-5. PMID 8625488 DOI: 10.1093/Carcin/17.4.761 |
0.35 |
|
| 1995 |
Frenkel K, Wei L, Wei H. 7,12-dimethylbenz[a]anthracene induces oxidative DNA modification in vivo. Free Radical Biology & Medicine. 19: 373-80. PMID 7557552 DOI: 10.1016/0891-5849(95)00046-Z |
0.348 |
|
| 1994 |
Suganuma M, Yoshizawa S, Yatsunami J, Nishiwaki S, Furuya H, Okabe S, Nishiwaki-Matsushima R, Frenkel K, Troll W, Verma AK. Mechanisms of action of new antitumor promoters. Basic Life Sciences. 61: 317-23. PMID 8304944 DOI: 10.1007/978-1-4615-2984-2_30 |
0.301 |
|
| 1994 |
Huang X, Zhuang Z, Frenkel K, Klein CB, Costa M. The role of nickel and nickel-mediated reactive oxygen species in the mechanism of nickel carcinogenesis. Environmental Health Perspectives. 102: 281-4. PMID 7843115 DOI: 10.1289/Ehp.94102S3281 |
0.372 |
|
| 1994 |
Frenkel K, Wei L, Wei H, Karkoszka J. Polycyclic Aromatic Hydrocarbons (PAH) Induce Oxidative Stress and Oxidative DNA Modification - Characteristics of Tumor Promotion Polycyclic Aromatic Compounds. 6: 151-160. DOI: 10.1080/10406639408031179 |
0.342 |
|
| 1993 |
Wei H, Frenkel K. Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters. Carcinogenesis. 14: 1195-201. PMID 8508507 DOI: 10.1093/Carcin/14.6.1195 |
0.34 |
|
| 1993 |
Pero RW, Berglund G, Christie NT, Cosma GN, Frenkel K, Garte SJ, Janzon L, Olsson A, Seidegård J, Smulson ME. The Malmö biomarker programme. Journal of Internal Medicine. 233: 69-74. PMID 8429290 DOI: 10.1111/J.1365-2796.1993.Tb00651.X |
0.311 |
|
| 1993 |
Wei H, Wei L, Frenkel K, Bowen R, Barnes S. Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein. Nutrition and Cancer. 20: 1-12. PMID 8415125 DOI: 10.1080/01635589309514265 |
0.411 |
|
| 1993 |
Wei L, Wei H, Frenkel K. Sensitivity to tumor promotion of SENCAR and C57BL/6J mice correlates with oxidative events and DNA damage. Carcinogenesis. 14: 841-7. PMID 8389253 DOI: 10.1093/Carcin/14.5.841 |
0.326 |
|
| 1993 |
Frenkel K, Karkoszka J, Kim E, Taioli E. Recognition of oxidized DNA bases by sera of patients with inflammatory diseases Free Radical Biology and Medicine. 14: 483-494. PMID 8349138 DOI: 10.1016/0891-5849(93)90105-4 |
0.305 |
|
| 1992 |
Frenkel K. Carcinogen-mediated oxidant formation and oxidative DNA damage. Pharmacology & Therapeutics. 53: 127-66. PMID 1641400 DOI: 10.1016/0163-7258(92)90047-4 |
0.344 |
|
| 1992 |
Patel U, Bhimani R, Frenkel K. Mechanism of mutagenicity by 5-hydroperoxymethyl-2'-deoxyuridine, an intermediate product of ionizing radiation, in bacteria. HPMdU bacterial mutagenicity and oxidation of DNA bases. Mutation Research. 283: 145-56. PMID 1381492 DOI: 10.1016/0165-7992(92)90147-A |
0.34 |
|
| 1991 |
Frenkel K, Zhong ZJ, Wei HC, Karkoszka J, Patel U, Rashid K, Georgescu M, Solomon JJ. Quantitative high-performance liquid chromatography analysis of DNA oxidized in vitro and in vivo. Analytical Biochemistry. 196: 126-36. PMID 1888026 DOI: 10.1016/0003-2697(91)90128-G |
0.319 |
|
| 1990 |
Troll W, Garte S, Frenkel K. Suppression of tumor promotion by inhibitors of poly(ADP)ribose formation. Basic Life Sciences. 52: 225-32. PMID 2109595 DOI: 10.1007/978-1-4615-9561-8_19 |
0.356 |
|
| 1990 |
Frenkel K, Wei H. Formation of oxidized nucleosides in DNA of mouse skin treated with tumor promoters Free Radical Biology and Medicine. 9: 170. DOI: 10.1016/0891-5849(90)90775-E |
0.312 |
|
| 1989 |
Frenkel K. Oxidation of DNA bases by tumor promoter-activated processes. Environmental Health Perspectives. 81: 45-54. PMID 2667984 DOI: 10.1289/Ehp.898145 |
0.357 |
|
| 1987 |
Troll W, Wiesner R, Frenkel K. Anticarcinogenic action of protease inhibitors. Advances in Cancer Research. 49: 265-83. PMID 3314395 DOI: 10.1016/S0065-230X(08)60800-3 |
0.317 |
|
| 1984 |
Teebor GW, Frenkel K, Goldstein MS. Ionizing radiation and tritium transmutation both cause formation of 5-hydroxymethyl-2'-deoxyuridine in cellular DNA Proceedings of the National Academy of Sciences of the United States of America. 81: 318-321. PMID 6582490 DOI: 10.1073/Pnas.81.2.318 |
0.301 |
|
| 1982 |
Teebor GW, Frenkel K, Goldstein MS. Identification of radiation-induced thymine derivatives in DNA Advances in Enzyme Regulation. 20: 39-54. PMID 7051772 DOI: 10.1016/0065-2571(82)90007-3 |
0.305 |
|
| 1981 |
Frenkel K, Goldstein MS, Teebor GW. Identification of the cis-thymine glycol moiety in chemically oxidized and γ-irradiated deoxyribonucleic acid by high-pressure liquid chromatography analysis Biochemistry. 20: 7566-7571. PMID 7326245 DOI: 10.1021/Bi00529A035 |
0.305 |
|
| 1972 |
Van Duuren BL, Katz C, Goldschmidt BM, Frenkel K, Sivak A. Carcinogenicity of halo-ethers. II. Structure-activity relationships of analogs of bis(chloromethyl)ether. Journal of the National Cancer Institute. 48: 1431-9. PMID 5030957 DOI: 10.1093/Jnci/48.5.1431 |
0.552 |
|
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