Ken McLeish - Publications

University of Louisville, Louisville 
Cell Biology

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lőrincz ÁM, Schütte M, Timár CI, Veres DS, Kittel Á, McLeish KR, Merchant ML, Ligeti E. Functionally and morphologically distinct populations of extracellular vesicles produced by human neutrophilic granulocytes. Journal of Leukocyte Biology. 98: 583-9. PMID 25986013 DOI: 10.1189/jlb.3VMA1014-514R  0.4
2015 Caster DJ, Hobeika L, Klein JB, Powell DW, McLeish KR. Changing the concepts of immune-mediated glomerular diseases through proteomics. Proteomics. Clinical Applications. PMID 25907758 DOI: 10.1002/prca.201400159  0.36
2015 Jin S, Merchant ML, Ritzenthaler JD, McLeish KR, Lederer ED, Torres-Gonzalez E, Fraig M, Barati MT, Lentsch AB, Roman J, Klein JB, Rane MJ. Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators. Plos One. 10: e0121637. PMID 25848767 DOI: 10.1371/journal.pone.0121637  0.36
2015 Caster DJ, Korte EA, Merchant ML, Klein JB, Wilkey DW, Rovin BH, Birmingham DJ, Harley JB, Cobb BL, Namjou B, McLeish KR, Powell DW. Autoantibodies targeting glomerular annexin A2 identify patients with proliferative lupus nephritis. Proteomics. Clinical Applications. PMID 25824007 DOI: 10.1002/prca.201400175  0.36
2015 Bai J, Tang L, Lomas-Neira J, Chen Y, McLeish KR, Uriarte SM, Chung CS, Ayala A. TAT-SNAP-23 treatment inhibits the priming of neutrophil functions contributing to shock and/or sepsis-induced extra-pulmonary acute lung injury. Innate Immunity. 21: 42-54. PMID 24391146 DOI: 10.1177/1753425913516524  0.36
2014 Arnett E, Vadia S, Nackerman CC, Oghumu S, Satoskar AR, McLeish KR, Uriarte SM, Seveau S. The pore-forming toxin listeriolysin O is degraded by neutrophil metalloproteinase-8 and fails to mediate Listeria monocytogenes intracellular survival in neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 192: 234-44. PMID 24319266 DOI: 10.4049/jimmunol.1301302  0.4
2013 Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G'sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, et al. ABIN1 dysfunction as a genetic basis for lupus nephritis. Journal of the American Society of Nephrology : Jasn. 24: 1743-54. PMID 23970121 DOI: 10.1681/ASN.2013020148  0.36
2013 McLeish KR, Merchant ML, Klein JB, Ward RA. Technical note: proteomic approaches to fundamental questions about neutrophil biology. Journal of Leukocyte Biology. 94: 683-92. PMID 23470899 DOI: 10.1189/jlb.1112591  0.44
2013 Uriarte SM, Rane MJ, Merchant ML, Jin S, Lentsch AB, Ward RA, McLeish KR. Inhibition of neutrophil exocytosis ameliorates acute lung injury in rats. Shock (Augusta, Ga.). 39: 286-92. PMID 23364427 DOI: 10.1097/SHK.0b013e318282c9a1  0.44
2013 McLeish KR, Uriarte SM, Tandon S, Creed TM, Le J, Ward RA. Exocytosis of neutrophil granule subsets and activation of prolyl isomerase 1 are required for respiratory burst priming. Journal of Innate Immunity. 5: 277-89. PMID 23363774 DOI: 10.1159/000345992  0.36
2013 Schissler MM, Zaidi S, Kumar H, Deo D, Brier ME, McLeish KR. Characteristics and outcomes in community-acquired versus hospital-acquired acute kidney injury. Nephrology (Carlton, Vic.). 18: 183-7. PMID 23336108 DOI: 10.1111/nep.12036  0.36
2013 Timár CI, Lorincz AM, Csépányi-Kömi R, Vályi-Nagy A, Nagy G, Buzás EI, Iványi Z, Kittel A, Powell DW, McLeish KR, Ligeti E. Antibacterial effect of microvesicles released from human neutrophilic granulocytes. Blood. 121: 510-8. PMID 23144171 DOI: 10.1182/blood-2012-05-431114  0.4
2012 Gomez-Cambronero J, Allen LA, Cathcart MK, Justement LB, Kovacs EJ, McLeish KR, Nauseef WM. Writing a first grant proposal. Nature Immunology. 13: 105-8. PMID 22261956 DOI: 10.1038/ni.2183  0.36
2011 Uriarte SM, Rane MJ, Luerman GC, Barati MT, Ward RA, Nauseef WM, McLeish KR. Granule exocytosis contributes to priming and activation of the human neutrophil respiratory burst. Journal of Immunology (Baltimore, Md. : 1950). 187: 391-400. PMID 21642540 DOI: 10.4049/jimmunol.1003112  0.44
2011 Luerman GC, Powell DW, Uriarte SM, Cummins TD, Merchant ML, Ward RA, McLeish KR. Identification of phosphoproteins associated with human neutrophil granules following chemotactic peptide stimulation. Molecular & Cellular Proteomics : McP. 10: M110.001552. PMID 21097543 DOI: 10.1074/mcp.M110.001552  0.44
2010 Luerman GC, Uriarte SM, Rane MJ, McLeish KR. Application of proteomics to neutrophil biology. Journal of Proteomics. 73: 552-61. PMID 19580889 DOI: 10.1016/j.jprot.2009.06.013  0.4
2009 Uriarte SM, Jog NR, Luerman GC, Bhimani S, Ward RA, McLeish KR. Counterregulation of clathrin-mediated endocytosis by the actin and microtubular cytoskeleton in human neutrophils. American Journal of Physiology. Cell Physiology. 296: C857-67. PMID 19176760 DOI: 10.1152/ajpcell.00454.2008  0.44
2009 Uriarte SM, McLeish KR, Ward RA. Anti-proteinase 3 antibodies both stimulate and prime human neutrophils. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 24: 1150-7. PMID 18952697 DOI: 10.1093/ndt/gfn580  0.44
2008 Uriarte SM, Powell DW, Luerman GC, Merchant ML, Cummins TD, Jog NR, Ward RA, McLeish KR. Comparison of proteins expressed on secretory vesicle membranes and plasma membranes of human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 180: 5575-81. PMID 18390742  0.44
2007 Barati MT, Merchant ML, Kain AB, Jevans AW, McLeish KR, Klein JB. Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice. American Journal of Physiology. Renal Physiology. 293: F1157-65. PMID 17609286 DOI: 10.1152/ajprenal.00411.2006  0.36
2007 Jog NR, Jala VR, Ward RA, Rane MJ, Haribabu B, McLeish KR. Heat shock protein 27 regulates neutrophil chemotaxis and exocytosis through two independent mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 178: 2421-8. PMID 17277149  0.44
2007 Jog NR, Rane MJ, Lominadze G, Luerman GC, Ward RA, McLeish KR. The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets. American Journal of Physiology. Cell Physiology. 292: C1690-700. PMID 17202227 DOI: 10.1152/ajpcell.00384.2006  0.44
2006 Lominadze G, Ward RA, Klein JB, McLeish KR. Proteomic analysis of human neutrophils. Methods in Molecular Biology (Clifton, N.J.). 332: 343-56. PMID 16878704 DOI: 10.1385/1-59745-048-0:343  0.44
2006 Barati MT, Rane MJ, Klein JB, McLeish KR. A proteomic screen identified stress-induced chaperone proteins as targets of Akt phosphorylation in mesangial cells. Journal of Proteome Research. 5: 1636-46. PMID 16823971 DOI: 10.1021/pr0502469  0.44
2005 Thongboonkerd V, Zheng S, McLeish KR, Epstein PN, Klein JB. Proteomic identification and immunolocalization of increased renal calbindin-D28k expression in OVE26 diabetic mice. The Review of Diabetic Studies : Rds. 2: 19-26. PMID 17491655 DOI: 10.1900/RDS.2005.2.19  0.44
2005 Lominadze G, Powell DW, Luerman GC, Link AJ, Ward RA, McLeish KR. Proteomic analysis of human neutrophil granules. Molecular & Cellular Proteomics : McP. 4: 1503-21. PMID 15985654 DOI: 10.1074/mcp.M500143-MCP200  0.36
2005 Lominadze G, Rane MJ, Merchant M, Cai J, Ward RA, McLeish KR. Myeloid-related protein-14 is a p38 MAPK substrate in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 174: 7257-67. PMID 15905572  0.44
2005 Rane MJ, Gozal D, Butt W, Gozal E, Pierce WM, Guo SZ, Wu R, Goldbart AD, Thongboonkerd V, McLeish KR, Klein JB. Gamma-amino butyric acid type B receptors stimulate neutrophil chemotaxis during ischemia-reperfusion. Journal of Immunology (Baltimore, Md. : 1950). 174: 7242-9. PMID 15905570  0.44
2005 Hirano S, Sun X, DeGuzman CA, Ransom RF, McLeish KR, Smoyer WE, Shelden EA, Welsh MJ, Benndorf R. p38 MAPK/HSP25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli. American Journal of Physiology. Renal Physiology. 288: F1133-43. PMID 15687248 DOI: 10.1152/ajprenal.00210.2004  0.36
2005 Powell DW, Pierce WM, McLeish KR. Defining mitogen-activated protein kinase pathways with mass spectrometry-based approaches. Mass Spectrometry Reviews. 24: 847-64. PMID 15619233 DOI: 10.1002/mas.20044  0.4
2004 Ward RA, McLeish KR. Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure? Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 19: 1702-7. PMID 15150351 DOI: 10.1093/ndt/gfh271  0.44
2004 Thongboonkerd V, Barati MT, McLeish KR, Benarafa C, Remold-O'Donnell E, Zheng S, Rovin BH, Pierce WM, Epstein PN, Klein JB. Alterations in the renal elastin-elastase system in type 1 diabetic nephropathy identified by proteomic analysis. Journal of the American Society of Nephrology : Jasn. 15: 650-62. PMID 14978167 DOI: 10.1097/01.ASN.0000115334.65095.9B  0.44
2004 Thongboonkerd V, Klein JB, Jevans AW, McLeish KR. Urinary proteomics and biomarker discovery for glomerular diseases. Contributions to Nephrology. 141: 292-307. PMID 14650240  0.44
2004 Barati MT, Powell DW, McLeish KR. Proteomic approach to identification of novel kinase substrates in mesangial cells. Contributions to Nephrology. 141: 231-44. PMID 14650236  0.4
2004 Thongboonkerd V, Barati MT, McLeish KR, Pierce WM, Epstein PN, Klein JB. Proteomics and diabetic nephropathy. Contributions to Nephrology. 141: 142-54. PMID 14650230  0.44
2003 Coxon PY, Rane MJ, Uriarte S, Powell DW, Singh S, Butt W, Chen Q, McLeish KR. MAPK-activated protein kinase-2 participates in p38 MAPK-dependent and ERK-dependent functions in human neutrophils. Cellular Signalling. 15: 993-1001. PMID 14499342  0.4
2003 Powell DW, Rane MJ, Joughin BA, Kalmukova R, Hong JH, Tidor B, Dean WL, Pierce WM, Klein JB, Yaffe MB, McLeish KR. Proteomic identification of 14-3-3ζ as a mitogen-activated protein kinase-activated protein kinase 2 substrate: Role in dimer formation and ligand binding Molecular and Cellular Biology. 23: 5376-5387. PMID 12861023 DOI: 10.1128/MCB.23.15.5376-5387.2003  0.36
2003 Singh S, Powell DW, Rane MJ, Millard TH, Trent JO, Pierce WM, Klein JB, Machesky LM, McLeish KR. Identification of the p16-Arc subunit of the Arp 2/3 complex as a substrate of MAPK-activated protein kinase 2 by proteomic analysis. The Journal of Biological Chemistry. 278: 36410-7. PMID 12829704 DOI: 10.1074/jbc.M306428200  0.44
2003 Rane MJ, Pan Y, Singh S, Powell DW, Wu R, Cummins T, Chen Q, McLeish KR, Klein JB. Heat shock protein 27 controls apoptosis by regulating Akt activation. The Journal of Biological Chemistry. 278: 27828-35. PMID 12740362 DOI: 10.1074/jbc.M303417200  0.44
2003 Chen Q, Powell DW, Rane MJ, Singh S, Butt W, Klein JB, McLeish KR. Akt phosphorylates p47phox and mediates respiratory burst activity in human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 170: 5302-8. PMID 12734380  0.44
2003 Ward RA, McLeish KR. Oxidant stress in hemodialysis patients: what are the determining factors? Artificial Organs. 27: 230-6. PMID 12662208  0.44
2003 Ward RA, Ouseph R, McLeish KR. Effects of high-flux hemodialysis on oxidant stress. Kidney International. 63: 353-9. PMID 12472803 DOI: 10.1046/j.1523-1755.2003.00741.x  0.44
2002 Thongboonkerd V, McLeish KR, Arthur JM, Klein JB. Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or ultracentrifugation. Kidney International. 62: 1461-9. PMID 12234320 DOI: 10.1111/j.1523-1755.2002.kid565.x  0.44
2002 Powell DW, Rane MJ, Chen Q, Singh S, McLeish KR. Identification of 14-3-3zeta as a protein kinase B/Akt substrate. The Journal of Biological Chemistry. 277: 21639-42. PMID 11956222 DOI: 10.1074/jbc.M203167200  0.4
2001 Klein JB, Buridi A, Coxon PY, Rane MJ, Manning T, Kettritz R, McLeish KR. Role of extracellular signal-regulated kinase and phosphatidylinositol-3 kinase in chemoattractant and LPS delay of constitutive neutrophil apoptosis. Cellular Signalling. 13: 335-43. PMID 11369515  0.44
2001 Rane MJ, Coxon PY, Powell DW, Webster R, Klein JB, Pierce W, Ping P, McLeish KR. p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils. The Journal of Biological Chemistry. 276: 3517-23. PMID 11042204 DOI: 10.1074/jbc.M005953200  0.44
2000 Ward RA, Nakamura M, McLeish KR. Priming of the neutrophil respiratory burst involves p38 mitogen-activated protein kinase-dependent exocytosis of flavocytochrome b558-containing granules. The Journal of Biological Chemistry. 275: 36713-9. PMID 10976103 DOI: 10.1074/jbc.M003017200  0.44
2000 Arthur JM, Lawrence MS, Payne CR, Rane MJ, McLeish KR. The calcium-sensing receptor stimulates JNK in MDCK cells. Biochemical and Biophysical Research Communications. 275: 538-41. PMID 10964699 DOI: 10.1006/bbrc.2000.3226  0.4
2000 Coxon PY, Rane MJ, Powell DW, Klein JB, McLeish KR. Differential mitogen-activated protein kinase stimulation by Fc gamma receptor IIa and Fc gamma receptor IIIb determines the activation phenotype of human neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 164: 6530-7. PMID 10843711  0.44
2000 Rane MJ, Prossnitz ER, Arthur JM, Ward RA, McLeish KR. Deficient homologous desensitization of formyl peptide receptors stably expressed in undifferentiated HL-60 cells. Biochemical Pharmacology. 60: 179-87. PMID 10825462  0.44
2000 Klein JB, Rane MJ, Scherzer JA, Coxon PY, Kettritz R, Mathiesen JM, Buridi A, McLeish KR. Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways. Journal of Immunology (Baltimore, Md. : 1950). 164: 4286-91. PMID 10754327  0.44
1999 Klein JB, McLeish KR, Ward RA. Transplantation, not dialysis, corrects azotemia-dependent priming of the neutrophil oxidative burst. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 33: 483-91. PMID 10070912  0.44
1998 McLeish KR, Klein JB, Coxon PY, Head KZ, Ward RA. Bacterial phagocytosis activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in human neutrophils. Journal of Leukocyte Biology. 64: 835-44. PMID 9850168  0.44
1998 McLeish KR, Knall C, Ward RA, Gerwins P, Coxon PY, Klein JB, Johnson GL. Activation of mitogen-activated protein kinase cascades during priming of human neutrophils by TNF-alpha and GM-CSF. Journal of Leukocyte Biology. 64: 537-45. PMID 9766635  0.44
1998 Rane MJ, Arthur JM, Prossnitz ER, McLeish KR. Activation of mitogen-activated protein kinases by formyl peptide receptors is regulated by the cytoplasmic tail. The Journal of Biological Chemistry. 273: 20916-23. PMID 9694839  0.4
1998 Rosenberg SJ, Rane MJ, Dean WL, Corpier CL, Hoffman JL, McLeish KR. Effect of gamma subunit carboxyl methylation on the interaction of G protein alpha subunits with beta gamma subunits of defined composition. Cellular Signalling. 10: 131-6. PMID 9481488  0.4
1997 Rane MJ, Carrithers SL, Arthur JM, Klein JB, McLeish KR. Formyl peptide receptors are coupled to multiple mitogen-activated protein kinase cascades by distinct signal transduction pathways: role in activation of reduced nicotinamide adenine dinucleotide oxidase. Journal of Immunology (Baltimore, Md. : 1950). 159: 5070-8. PMID 9366435  0.44
1997 Scherzer JA, Lin Y, McLeish KR, Klein JB. TNF translationally modulates the expression of G1 protein alpha(i2) subunits in human polymorphonuclear leukocytes. Journal of Immunology (Baltimore, Md. : 1950). 158: 913-8. PMID 8993011  0.44
1996 McLeish KR, Klein JB, Lederer ED, Head KZ, Ward RA. Azotemia, TNF alpha, and LPS prime the human neutrophil oxidative burst by distinct mechanisms. Kidney International. 50: 407-16. PMID 8840267  0.44
1995 Ward RA, McLeish KR. Hemodialysis with cellulose membranes primes the neutrophil oxidative burst. Artificial Organs. 19: 801-7. PMID 8572999  0.44
1995 Klein JB, Scherzer JA, Harding G, Jacobs AA, McLeish KR. TNF-alpha stimulates increased plasma membrane guanine nucleotide binding protein activity in polymorphonuclear leukocytes. Journal of Leukocyte Biology. 57: 500-6. PMID 7884323  0.44
1995 Ward RA, McLeish KR. Polymorphonuclear leukocyte oxidative burst is enhanced in patients with chronic renal insufficiency. Journal of the American Society of Nephrology : Jasn. 5: 1697-702. PMID 7780059  0.44
1995 Jacobs AA, Huber JL, Ward RA, Klein JB, McLeish KR. Chemoattractant receptor-specific differences in G protein activation rates regulate effector enzyme and functional responses. Journal of Leukocyte Biology. 57: 679-86. PMID 7722425  0.44
1994 Lederer ED, Jacobs AA, Hoffman JL, Harding GB, Robishaw JD, McLeish KR, Mcleish KR. Role of carboxylmethylation in chemoattractant receptor-stimulated G protein activation and functional responses Biochemical and Biophysical Research Communications. 200: 1604-1614. PMID 8185616 DOI: 10.1006/bbrc.1994.1635  0.36
1994 Miller ES, Koebel DA, Davis SA, Klein JB, McLeish KR, Goldwater D, Sonnenfeld G. Influence of suspension on the oxidative burst by rat neutrophils. Journal of Applied Physiology (Bethesda, Md. : 1985). 76: 387-90. PMID 8175533  0.44
1994 McLeish KR, Lederer ED, Klein JB, Hoffman JL. Effect of prenylcysteine analogues on chemoattractant receptor-mediated G protein activation Cellular Signalling. 6: 569-579. PMID 7818993 DOI: 10.1016/0898-6568(94)90011-6  0.36
1993 Erbeck K, Klein JB, McLeish KR. Differential uncoupling of chemoattractant receptors from G proteins in retinoic acid-differentiated HL-60 granulocytes. Journal of Immunology (Baltimore, Md. : 1950). 150: 1913-21. PMID 8382247  0.44
1993 McLeish KR, Lederer ED, Klein JB. Role of isoprenoid metabolism in chemotactic peptide receptor-mediated G protein activation. Biochemical and Biophysical Research Communications. 197: 763-70. PMID 8267613 DOI: 10.1006/bbrc.1993.2544  0.44
1992 Klein JB, Scherzer JA, McLeish KR. IFN-gamma enhances expression of formyl peptide receptors and guanine nucleotide-binding proteins by HL-60 granulocytes. Journal of Immunology (Baltimore, Md. : 1950). 148: 2483-8. PMID 1560204  0.44
1992 Schepers TM, Klein JB, Feldhoff PW, Dean WL, McLeish KR. Interferon-gamma induces phosphorylation of multiple small-molecular-weight proteins in U937 cells. Journal of Interferon Research. 12: 289-96. PMID 1331258  0.44
1991 McLeish KR, Klein JB, Schepers T, Sonnenfeld G. Modulation of transmembrane signalling in HL-60 granulocytes by tumour necrosis factor-alpha. The Biochemical Journal. 279: 455-60. PMID 1659380  0.44
1991 Klein JB, Sonnenfeld G, McLeish KR. Priming of the HL-60 cell respiratory burst response by tumor necrosis factor-alpha. Lymphokine and Cytokine Research. 10: 173-6. PMID 1653047  0.44
1991 Klein JB, Scherzer JA, McLeish KR. Interferon-gamma enhances superoxide production by HL-60 cells stimulated with multiple agonists. Journal of Interferon Research. 11: 69-74. PMID 1651364  0.44
1990 Klein JB, Payne V, Schepers TM, McLeish KR. Bacterial lipopolysaccharide enhances polymorphonuclear leukocyte function independent of changes in intracellular calcium. Inflammation. 14: 599-611. PMID 2147424  0.44
1990 Klein JB, Schepers TM, Dean WL, Sonnenfeld G, McLeish KR. Role of intracellular calcium concentration and protein kinase C activation in IFN-gamma stimulation of U937 cells. Journal of Immunology (Baltimore, Md. : 1950). 144: 4305-11. PMID 2140394  0.44
1989 Jacobs AA, Ward RA, Wellhausen SR, McLeish KR. Polymorphonuclear leukocyte function during hemodialysis: relationship to complement activation. Nephron. 52: 119-24. PMID 2739846  0.44
1988 Klein JB, McLeish KR, Bunke CM, Chang B, Ganzel BL, Slater AD, Gray LA. Use of OKT3 monoclonal antibody in the treatment of acute cardiac allograft rejection. Transplantation. 45: 727-9. PMID 3282354  0.44
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