| Year |
Citation |
Score |
| 2020 |
Kiseleva AA, Nikonova AS, Golemis EA. Patterns of Ciliation and Ciliary Signaling in Cancer. Reviews of Physiology, Biochemistry and Pharmacology. PMID 32761455 DOI: 10.1007/112_2020_36 |
0.369 |
|
| 2020 |
Tricarico R, Nicolas E, Hall MJ, Golemis EA. X- and Y-linked chromatin-modifying genes as regulators of sex-specific cancer incidence and prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32732223 DOI: 10.1158/1078-0432.Ccr-20-1741 |
0.361 |
|
| 2020 |
Serebriiskii IG, Elmekawy M, Golemis EA. Identification of the KRIT1 Protein by LexA-Based Yeast Two-Hybrid System. Methods in Molecular Biology (Clifton, N.J.). 2152: 269-289. PMID 32524559 DOI: 10.1007/978-1-0716-0640-7_20 |
0.37 |
|
| 2020 |
Zhang YW, Nasto RE, Jablonski SA, Serebriiskii IG, Surana R, Murray J, Johnson M, Riggins RB, Clarke R, Golemis EA, Weiner LM. RNA interference screening methods to identify proliferation determinants and mechanisms of resistance to immune attack. Methods in Enzymology. 636: 299-322. PMID 32178823 DOI: 10.1016/Bs.Mie.2019.06.002 |
0.335 |
|
| 2020 |
Deneka AY, Einarson MB, Bennett J, Nikonova AS, Elmekawy M, Zhou Y, Lee JW, Burtness BA, Golemis EA. Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer. Cancers. 12. PMID 32012873 DOI: 10.3390/Cancers12020306 |
0.337 |
|
| 2020 |
Kharin L, Karnaukhov NS, Voloshin M, Milakin AG, Bychkov I, Deneka A, Frantsiyants EM, Kit OI, Golemis E, Boumber Y. Prognostic significance of Musashi 2 (MSI2) RNA-binding protein expression in precancerous polyps and during colorectal cancer (CRC) progression. Journal of Clinical Oncology. 38. DOI: 10.1200/Jco.2020.38.15_Suppl.E16009 |
0.362 |
|
| 2019 |
Parker MI, Nikonova AS, Sun D, Golemis EA. Proliferative signaling by ERBB proteins and RAF/MEK/ERK effectors in polycystic kidney disease. Cellular Signalling. 67: 109497. PMID 31830556 DOI: 10.1016/J.Cellsig.2019.109497 |
0.383 |
|
| 2019 |
Deneka AY, Boumber Y, Beck T, Golemis EA. Tumor-Targeted Drug Conjugates as an Emerging Novel Therapeutic Approach in Small Cell Lung Cancer (SCLC). Cancers. 11. PMID 31484422 DOI: 10.3390/Cancers11091297 |
0.336 |
|
| 2019 |
Korobeynikov V, Borakove M, Feng Y, Wuest WM, Koval AB, Nikonova AS, Serebriiskii I, Chernoff J, Borges VF, Golemis EA, Shagisultanova E. Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer. Breast Cancer Research and Treatment. PMID 31254157 DOI: 10.1007/S10549-019-05329-2 |
0.334 |
|
| 2019 |
Kiseleva AA, Korobeynikov VA, Nikonova AS, Zhang P, Makhov P, Deneka AY, Einarson MB, Serebriiskii IG, Liu H, Peterson JR, Golemis EA. Unexpected activities in regulating ciliation contribute to off-target effects of targeted drugs. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30867219 DOI: 10.1158/1078-0432.Ccr-18-3535 |
0.425 |
|
| 2019 |
Zhang P, Kiseleva AA, Korobeynikov V, Liu H, Einarson MB, Golemis EA. Microscopy-Based Automated Live Cell Screening for Small Molecules That Affect Ciliation. Frontiers in Genetics. 10: 75. PMID 30809247 DOI: 10.3389/Fgene.2019.00075 |
0.406 |
|
| 2019 |
Deneka AY, Nikonova A, Kopp M, Gaponova A, Kiseleva A, Hensley H, Golemis E. Abstract 1840:Nedd9controls glycolysis and autophagy in non-small cell lung cancer (NSCLC) Cancer Research. 79: 1840-1840. DOI: 10.1158/1538-7445.Sabcs18-1840 |
0.411 |
|
| 2019 |
Kudinov A, Makhov P, Faezov B, Bychkov I, Deneka A, Nicolas E, Caid KQQ, Brebione R, Avrilf E, Nikonova AS, Serebriiskii IG, Borghaei H, Golemis EA, Boumber Y. Abstract 955: Musashi-2 regulates EGFR expression in NSCLC, cell proliferation and survival, response to EGFR inhibitors in EGFR-mutant NSCLC Cancer Research. 79: 955-955. DOI: 10.1158/1538-7445.Am2019-955 |
0.361 |
|
| 2019 |
Nikonova AS, Kiseleva A, Serebriiskii I, Grivennikov S, Golemis EA. Abstract 419: PKD1 regulates susceptibility to ulcerative colitis and colorectal cancer Cancer Research. 79: 3459-3459. DOI: 10.1158/1538-7445.Am2019-3459 |
0.345 |
|
| 2018 |
Liu H, Kiseleva AA, Golemis EA. Ciliary signalling in cancer. Nature Reviews. Cancer. PMID 29802351 DOI: 10.1038/S41568-018-0023-6 |
0.362 |
|
| 2018 |
Gabbasov R, Xiao F, Howe CG, Bickel LE, O'Brien SW, Benrubi D, Do TV, Zhou Y, Nicolas E, Cai KQ, Litwin S, Seo S, Golemis EA, Connolly DC. NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice. Oncogene. PMID 29773902 DOI: 10.1038/S41388-018-0296-Y |
0.388 |
|
| 2018 |
Nikonova AS, Deneka AY, Kiseleva AA, Korobeynikov V, Gaponova A, Serebriiskii IG, Kopp MC, Hensley HH, Seeger-Nukpezah TN, Somlo S, Proia DA, Golemis EA. Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201700909R. PMID 29401581 DOI: 10.1096/Fj.201700909R |
0.307 |
|
| 2018 |
Makhov P, Kudinov A, Deneka A, Egleston BL, Nicolas E, Cai KQ, Brebion R, Avril E, Hitrik M, Nikonova AS, Serebriiskii IG, Khazak V, Borghaei H, Golemis EA, Boumber Y. Abstract 4452: Musashi-2 regulates EGFR/HER3 expression in NSCLC, cell proliferation and response to EGFR inhibitors in EGFR-mutant NSCLC Cancer Research. 78: 4452-4452. DOI: 10.1158/1538-7445.Am2018-4452 |
0.349 |
|
| 2018 |
Bagnyukova T, Egleston B, Kramer M, Astsaturov I, Golemis E, Borghaei H. Abstract 3469: Dual inhibition of the EGFR and Aurora A pathways in Kras mutated non-small cell lung cancers Cancer Research. 78: 3469-3469. DOI: 10.1158/1538-7445.Am2018-3469 |
0.336 |
|
| 2017 |
Peri S, Izumchenko E, Schubert AD, Slifker MJ, Ruth K, Serebriiskii IG, Guo T, Burtness BA, Mehra R, Ross EA, Sidransky D, Golemis EA. NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis. Nature Communications. 8: 1772. PMID 29176703 DOI: 10.1038/S41467-017-01877-7 |
0.304 |
|
| 2017 |
Arora S, Huwe PJ, Sikder R, Shah M, Browne AJ, Lesh R, Nicolas E, Deshpande S, Hall MJ, Dunbrack RL, Golemis EA. Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods. Cancer Biology & Therapy. 0. PMID 28494185 DOI: 10.1080/15384047.2017.1326439 |
0.333 |
|
| 2017 |
Deneka AY, Haber L, Kopp MC, Gaponova AV, Nikonova AS, Golemis EA. Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model. Plos One. 12: e0176747. PMID 28453558 DOI: 10.1371/Journal.Pone.0176747 |
0.359 |
|
| 2017 |
Korobeynikov V, Deneka AY, Golemis EA. Mechanisms for nonmitotic activation of Aurora-A at cilia. Biochemical Society Transactions. 45: 37-49. PMID 28202658 DOI: 10.1042/Bst20160142 |
0.366 |
|
| 2017 |
Boumber Y, Kudinov AE, Karanicolas J, Golemis EA. Musashi RNA-binding proteins as cancer drivers and novel therapeutic targets. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28143872 DOI: 10.1158/1078-0432.Ccr-16-2728 |
0.453 |
|
| 2017 |
Franco-Barraza J, Francescone R, Luong T, Shah N, Madhani R, Cukierman G, Dulaimi E, Devarajan K, Egleston BL, Nicolas E, Katherine Alpaugh R, Malik R, Uzzo RG, Hoffman JP, Golemis EA, et al. Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence. Elife. 6. PMID 28139197 DOI: 10.7554/Elife.20600 |
0.321 |
|
| 2017 |
Kudinov A, Deneka A, Nikonova AN, Nicolas E, Korobeynikov VA, Serebriiskii IG, Karanicolas J, Golemis EA, Boumber Y. Abstract 3878: Musashi-2 (MSI2) regulation of ERBB family proteins in non-small cell lung cancer (NSCLC) Cancer Research. 77: 3878-3878. DOI: 10.1158/1538-7445.Am2017-3878 |
0.34 |
|
| 2016 |
Beck TN, Golemis EA. Genomic insights into head and neck cancer. Cancers of the Head & Neck. 1. PMID 29034103 DOI: 10.1186/S41199-016-0003-Z |
0.308 |
|
| 2016 |
Gaponova AV, Deneka AY, Beck TN, Liu H, Andrianov G, Nikonova AS, Nicolas E, Einarson MB, Golemis EA, Serebriiskii IG. Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin. Oncotarget. PMID 27863405 DOI: 10.18632/Oncotarget.13353 |
0.358 |
|
| 2016 |
Bobrov E, Skobeleva N, Restifo D, Beglyarova N, Cai KQ, Handorf E, Campbell K, Proia DA, Khazak V, Golemis EA, Astsaturov I. Targeted delivery of chemotherapy using HSP90 inhibitor drug conjugates is highly active against pancreatic cancer models. Oncotarget. PMID 27779106 DOI: 10.18632/Oncotarget.12642 |
0.347 |
|
| 2016 |
Gray PN, Vuong H, Tsai P, Lu HM, Mu W, Hsuan V, Hoo J, Shah S, Uyeda L, Fox S, Patel H, Janicek M, Brown S, Dobrea L, Wagman L, ... ... Golemis EA, et al. TumorNext: A comprehensive tumor profiling assay that incorporates high resolution copy number analysis and germline status to improve testing accuracy. Oncotarget. PMID 27626691 DOI: 10.18632/Oncotarget.11910 |
0.318 |
|
| 2016 |
Beck TN, Georgopoulos R, Shagisultanova EI, Sarcu D, Handorf EA, Dubyk C, Lango MN, Ridge JA, Astsaturov I, Serebriiskii IG, Burtness BA, Mehra R, Golemis EA. EGFR and RB1 as Dual Biomarkers in HPV-negative Head and Neck Cancer. Molecular Cancer Therapeutics. PMID 27507850 DOI: 10.1158/1535-7163.Mct-16-0243 |
0.35 |
|
| 2016 |
Beck TN, Korobeynikov VA, Kudinov AE, Georgopoulos R, Solanki NR, Andrews-Hoke M, Kistner TM, Pépin D, Donahoe PK, Nicolas E, Einarson MB, Zhou Y, Boumber Y, Proia DA, Serebriiskii IG, ... Golemis EA, et al. Anti-Müllerian Hormone Signaling Regulates Epithelial Plasticity and Chemoresistance in Lung Cancer. Cell Reports. PMID 27396341 DOI: 10.1016/J.Celrep.2016.06.043 |
0.368 |
|
| 2016 |
Beglyarova N, Banina E, Zhou Y, Mukhamadeeva R, Andrianov G, Bobrov E, Lysenko E, Skobeleva N, Gabitova L, Restifo D, Pressman M, Serebriiskii IG, Hoffman JP, Paz K, Behrens D, ... ... Golemis EA, et al. Screening of conditionally reprogrammed patient-derived carcinoma cells identifies ERCC3-MYC interactions as a target in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27384421 DOI: 10.1158/1078-0432.Ccr-16-0149 |
0.328 |
|
| 2016 |
Nicolas E, Golemis EA, Arora S. POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies. Gene. PMID 27320729 DOI: 10.1016/J.Gene.2016.06.031 |
0.304 |
|
| 2016 |
Kudinov AE, Deneka A, Nikonova AS, Beck TN, Ahn YH, Liu X, Martinez CF, Schultz FA, Reynolds S, Yang DH, Cai KQ, Yaghmour KM, Baker KA, Egleston BL, Nicolas E, ... ... Golemis EA, et al. Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27274057 DOI: 10.1073/Pnas.1513616113 |
0.394 |
|
| 2016 |
Gaponova AV, Nikonova A, Deneka AY, Kopp MC, Kudinov AE, Skobeleva N, Khazak V, Shin Ogawa L, Cai KQ, Duncan KE, Duncan JS, Egleston BL, Proia DA, Boumber Y, Golemis EA. A novel HSP90 inhibitor-drug conjugate to SN38 is highly effective in small cell lung cancer (SCLC). Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27267850 DOI: 10.1158/1078-0432.Ccr-15-3068 |
0.309 |
|
| 2016 |
Astsaturov I, Jablonski SA, Zhou Y, Serebriiskii I, Keren P, Weiner LM, Golemis E, Khazak V. Abstract A77: Screening of conditionally reprogrammed patient-derived carcinoma cells identifies ERCC3-MYC interactions as a target in pancreatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A77 |
0.318 |
|
| 2016 |
Beck TN, Korobeynikov V, Kudinov A, Georgeopoulos R, Nicolas E, Einarson MB, Zhou Y, Boumber Y, Proia DA, Serebriiskii IG, Golemis EA. Abstract B25: Anti-Mullerian hormone (AMH) supports epithelial identity and survival signaling in lung cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Fbcr15-B25 |
0.399 |
|
| 2016 |
Arora S, Huwe PJ, Sikder R, Shah M, Deshpande S, Hall MJ, Dunbrack RL, Golemis EA. Abstract 5286: A pipeline for developing a novel, predictive tool to classify variants of uncertain significance (VUS) in Lynch Syndrome Cancer Research. 76: 5286-5286. DOI: 10.1158/1538-7445.Am2016-5286 |
0.317 |
|
| 2016 |
Kudinov A, Deneka A, Nikonova A, Serebriiskii I, Beck TN, Cai Q, Egleston BL, Nicolas E, Borghaei H, Gibbons D, Kurie J, Golemis EA, Boumber Y. Abstract 1584: Musashi-2 (MSI2) drives TGFBR1/SMAD3 dependent partial EMT and supports VEGFR2 expression and metastasis of human and mouse NSCLC cells Cancer Research. 76: 1584-1584. DOI: 10.1158/1538-7445.Am2016-1584 |
0.394 |
|
| 2016 |
Shagisultanova E, Korobeynikov V, Nikonova A, Chernoff J, Borges V, Golemis E. Abstract 1242: Combination of p21-activated kinase 1 (PAK1) inhibitor FRAX1036 and Aurora-A inhibitor alisertib is effective in hormone receptor-positive breast cancer Cancer Research. 76: 1242-1242. DOI: 10.1158/1538-7445.Am2016-1242 |
0.344 |
|
| 2015 |
Pathak HB, Zhou Y, Sethi G, Hirst J, Schilder RJ, Golemis EA, Godwin AK. A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer. Plos One. 10: e0144126. PMID 26637171 DOI: 10.1371/Journal.Pone.0144126 |
0.388 |
|
| 2015 |
Nikonova AS, Deneka AY, Eckman L, Kopp MC, Hensley HH, Egleston BL, Golemis EA. Opposing Effects of Inhibitors of Aurora-A and EGFR in Autosomal-Dominant Polycystic Kidney Disease. Frontiers in Oncology. 5: 228. PMID 26528438 DOI: 10.3389/Fonc.2015.00228 |
0.383 |
|
| 2015 |
Gabitova L, Restifo D, Gorin A, Manocha K, Handorf E, Yang DH, Cai KQ, Klein-Szanto AJ, Cunningham D, Kratz LE, Herman GE, Golemis EA, Astsaturov I. Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR. Cell Reports. 12: 1927-38. PMID 26344763 DOI: 10.1016/J.Celrep.2015.08.023 |
0.306 |
|
| 2015 |
Nikonova AS, Golemis EA. The tumor suppressor FBW7 controls ciliary length. The Embo Journal. 34: 2388-90. PMID 26269527 DOI: 10.15252/Embj.201592588 |
0.337 |
|
| 2015 |
Beck TN, Kaczmar J, Handorf E, Nikonova A, Dubyk C, Peri S, Lango M, Ridge JA, Serebriiskii IG, Burtness B, Golemis EA, Mehra R. Phospho-T356RB1 predicts survival in HPV-negative squamous cell carcinoma of the head and neck. Oncotarget. 6: 18863-74. PMID 26265441 DOI: 10.18632/Oncotarget.4321 |
0.304 |
|
| 2015 |
Zhang YW, Nasto RE, Varghese R, Jablonski SA, Serebriiskii IG, Surana R, Calvert VS, Bebu I, Murray J, Jin L, Johnson M, Riggins R, Ressom H, Petricoin E, Clarke R, ... Golemis EA, et al. Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation. Oncogene. PMID 26165839 DOI: 10.1038/Onc.2015.226 |
0.335 |
|
| 2015 |
Deneka A, Korobeynikov V, Golemis EA. Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members. Gene. 570: 25-35. PMID 26119091 DOI: 10.1016/J.Gene.2015.06.062 |
0.384 |
|
| 2015 |
Ramirez UD, Nikonova AS, Liu H, Pecherskaya A, Lawrence SH, Serebriiskii IG, Zhou Y, Robinson MK, Einarson MB, Golemis EA, Jaffe EK. Compounds identified by virtual docking to a tetrameric EGFR extracellular domain can modulate Grb2 internalization. Bmc Cancer. 15: 436. PMID 26016476 DOI: 10.1186/S12885-015-1415-6 |
0.333 |
|
| 2015 |
Shagisultanova E, Gaponova AV, Gabbasov R, Nicolas E, Golemis EA. Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases. Gene. 567: 1-11. PMID 25967390 DOI: 10.1016/J.Gene.2015.04.086 |
0.431 |
|
| 2015 |
Shagisultanova E, Dunbrack RL, Golemis EA. Issues in interpreting the in vivo activity of Aurora-A. Expert Opinion On Therapeutic Targets. 19: 187-200. PMID 25384454 DOI: 10.1517/14728222.2014.981154 |
0.329 |
|
| 2015 |
Boumber Y, Gaponova A, Nikonova AS, Deneka A, Kudinov A, Egleston BL, Duncan JS, Duncan K, Borghaei H, Mehra R, Proia DA, Golemis E. Preclinical efficacy of STA-12-8666, an HSP90 inhibitor-targeted SN-38 conjugate, in small cell lung cancer (SCLC). Journal of Clinical Oncology. 33: e18560-e18560. DOI: 10.1200/Jco.2015.33.15_Suppl.E18560 |
0.357 |
|
| 2015 |
Nicolas E, Zhou Y, Serebriiskii IG, Andrake MD, Handorf EA, Dunbrack RL, Giri VN, Ross EA, Golemis EA, Hall MJ, Daly MB. Abstract 537: Information-driven approaches to predicting familial risk for prostate cancer Cancer Research. 75: 537-537. DOI: 10.1158/1538-7445.Am2015-537 |
0.3 |
|
| 2015 |
Kudinov A, Deneka AD, Nikonova A, Ahn Y, Liu XL, Serebriiskii I, Efimov A, Yang D, Andrake MA, Nicolas E, Egleston B, Borghaei H, Gibbons D, Kurie J, Golemis E, et al. Abstract 4098: Musashi-2 (MSI2) activates TGF-β signaling and inhibits CLDN7 to promote non-small cell lung cancer (NSCLC) metastasis Cancer Research. 75: 4098-4098. DOI: 10.1158/1538-7445.Am2015-4098 |
0.405 |
|
| 2015 |
Beck T, Nicolas E, Zhou Y, Serebriiskii I, Golemis E. Abstract 34: AMH and AMHR2 regulate survival signaling, epithelial-mesenchymal transition (EMT) and resistance to HSP90 inhibition in non-small cell lung cancer (NSCLC) Cancer Research. 75: 34-34. DOI: 10.1158/1538-7445.Am2015-34 |
0.385 |
|
| 2015 |
Gaponova A, Nikonova A, Deneka A, Egleston B, Litwin S, Duncan J, Duncan K, Borghaei H, Mehra R, Proia D, Boumber Y, Golemis E. Abstract 1731: Preclinical testing demonstrates strong activity of STA-12-8666, an HSP90 inhibitor-SN-38 conjugate, in small cell lung cancer (SCLC) Cancer Research. 75: 1731-1731. DOI: 10.1158/1538-7445.Am2015-1731 |
0.352 |
|
| 2015 |
Zhang Y, Nasto RE, Varghese R, Jablonski SA, Serebriiskii IG, Surana R, Calvert VS, Bebu I, Murray J, Jin L, Johnson M, Riggins R, Ressom H, Petricoin E, Clarke R, ... Golemis EA, et al. Abstract 1716: Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation Cancer Research. 75: 1716-1716. DOI: 10.1158/1538-7445.Am2015-1716 |
0.332 |
|
| 2014 |
Smithline ZB, Nikonova AS, Hensley HH, Cai KQ, Egleston BL, Proia DA, Seeger-Nukpezah T, Golemis EA. Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice. Plos One. 9: e114403. PMID 25474361 DOI: 10.1371/Journal.Pone.0114403 |
0.311 |
|
| 2014 |
Nikonova AS, Plotnikova OV, Serzhanova V, Efimov A, Bogush I, Cai KQ, Hensley HH, Egleston BL, Klein-Szanto A, Seeger-Nukpezah T, Golemis EA. Nedd9 restrains renal cystogenesis in Pkd1-/- mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 12859-64. PMID 25139996 DOI: 10.1073/Pnas.1405362111 |
0.339 |
|
| 2014 |
Beck TN, Chikwem AJ, Solanki NR, Golemis EA. Bioinformatic approaches to augment study of epithelial-to-mesenchymal transition in lung cancer. Physiological Genomics. 46: 699-724. PMID 25096367 DOI: 10.1152/Physiolgenomics.00062.2014 |
0.313 |
|
| 2014 |
Nikonova AS, Gaponova AV, Kudinov AE, Golemis EA. CAS proteins in health and disease: an update. Iubmb Life. 66: 387-95. PMID 24962474 DOI: 10.1002/Iub.1282 |
0.362 |
|
| 2014 |
Liu H, Beck TN, Golemis EA, Serebriiskii IG. Integrating in silico resources to map a signaling network. Methods in Molecular Biology (Clifton, N.J.). 1101: 197-245. PMID 24233784 DOI: 10.1007/978-1-62703-721-1_11 |
0.357 |
|
| 2014 |
Do TV, Xiao F, Bickel LE, Klein-Szanto AJ, Pathak HB, Hua X, Howe C, O'Brien SW, Maglaty M, Ecsedy JA, Litwin S, Golemis EA, Schilder RJ, Godwin AK, Connolly DC. Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion. Oncogene. 33: 539-49. PMID 23334327 DOI: 10.1038/Onc.2012.632 |
0.399 |
|
| 2014 |
Little JL, Serzhanova V, Izumchenko E, Egleston BL, Parise E, Klein-Szanto AJ, Loudon G, Shubina M, Seo S, Kurokawa M, Ochs MF, Golemis EA. A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice. Oncogene. 33: 411-20. PMID 23318423 DOI: 10.1038/Onc.2012.607 |
0.374 |
|
| 2014 |
Gabbasov R, Bickel LE, O'Brien SW, Litwin S, Seo S, Golemis EA, Connolly DC. Abstract 989: NEDD9 expression promotes epithelial ovarian cancer growth and dissemination Cancer Research. 74: 989-989. DOI: 10.1158/1538-7445.Am2014-989 |
0.34 |
|
| 2014 |
Mehra R, Yang D, Handorf E, Serebriiskii I, Ross E, Lango M, Ridge JA, Golemis E, Burtness B. Abstract 4743: Analysis of a protein expression biomarkers in HPV negative SCCHN Cancer Research. 74: 4743-4743. DOI: 10.1158/1538-7445.Am2014-4743 |
0.341 |
|
| 2014 |
Bagnyukova T, Pan X, Zhang J, Egleston B, Astsaturov I, Golemis E, Borghaei H. Abstract 4242: Effects of dual inhibition of EGFR and Aurora A kinase in a lung cancer model Cancer Research. 74: 4242-4242. DOI: 10.1158/1538-7445.Am2014-4242 |
0.366 |
|
| 2013 |
Khazak V, Eyrisch S, Kato J, Tamanoi F, Golemis EA. A two-hybrid approach to identify inhibitors of the RAS-RAF interaction. The Enzymes. 33: 213-48. PMID 25033807 DOI: 10.1016/B978-0-12-416749-0.00010-5 |
0.331 |
|
| 2013 |
Seeger-Nukpezah T, Little JL, Serzhanova V, Golemis EA. Cilia and cilia-associated proteins in cancer. Drug Discovery Today. Disease Mechanisms. 10: e135-e142. PMID 24982684 DOI: 10.1016/J.Ddmec.2013.03.004 |
0.378 |
|
| 2013 |
Mehra R, Zhu F, Yang DH, Cai KQ, Weaver J, Singh MK, Nikonova AS, Golemis EA, Flieder DB, Cooper HS, Lango M, Ridge JA, Burtness B. Quantification of excision repair cross-complementing group 1 and survival in p16-negative squamous cell head and neck cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6633-43. PMID 24088734 DOI: 10.1158/1078-0432.Ccr-13-0152 |
0.308 |
|
| 2013 |
Mehra R, Serebriiskii IG, Burtness B, Astsaturov I, Golemis EA. Aurora kinases in head and neck cancer. The Lancet. Oncology. 14: e425-35. PMID 23993387 DOI: 10.1016/S1470-2045(13)70128-1 |
0.326 |
|
| 2013 |
Liu H, Xiao F, Serebriiskii IG, O'Brien SW, Maglaty MA, Astsaturov I, Litwin S, Martin LP, Proia DA, Golemis EA, Connolly DC. Network analysis identifies an HSP90-central hub susceptible in ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5053-67. PMID 23900136 DOI: 10.1158/1078-0432.Ccr-13-1115 |
0.362 |
|
| 2013 |
Seeger-Nukpezah T, Proia DA, Egleston BL, Nikonova AS, Kent T, Cai KQ, Hensley HH, Ying W, Chimmanamada D, Serebriiskii IG, Golemis EA. Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 12786-91. PMID 23858461 DOI: 10.1073/Pnas.1301904110 |
0.318 |
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| 2013 |
Bagnyukova TV, Restifo D, Beeharry N, Gabitova L, Li T, Serebriiskii IG, Golemis EA, Astsaturov I. DUSP6 regulates drug sensitivity by modulating DNA damage response. British Journal of Cancer. 109: 1063-71. PMID 23839489 DOI: 10.1038/Bjc.2013.353 |
0.358 |
|
| 2013 |
Sukhanova A, Gorin A, Serebriiskii IG, Gabitova L, Zheng H, Restifo D, Egleston BL, Cunningham D, Bagnyukova T, Liu H, Nikonova A, Adams GP, Zhou Y, Yang DH, Mehra R, ... ... Golemis EA, et al. Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation. Cancer Discovery. 3: 96-111. PMID 23125191 DOI: 10.1158/2159-8290.Cd-12-0031 |
0.333 |
|
| 2013 |
Nikonova AS, Astsaturov I, Serebriiskii IG, Dunbrack RL, Golemis EA. Aurora A kinase (AURKA) in normal and pathological cell division. Cellular and Molecular Life Sciences : Cmls. 70: 661-87. PMID 22864622 DOI: 10.1007/S00018-012-1073-7 |
0.4 |
|
| 2013 |
Pan J, Seeger-Nukpezah T, Golemis EA. The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies. Cellular and Molecular Life Sciences : Cmls. 70: 1849-74. PMID 22782110 DOI: 10.1007/S00018-012-1052-Z |
0.341 |
|
| 2012 |
Burtness B, Marur S, Bauman JE, Golemis EA, Mehra R, Cohen SJ. Comment on "epidermal growth factor receptor is essential for toll-like receptor 3 signaling". Science Signaling. 5: lc5. PMID 23233526 DOI: 10.1126/Scisignal.2003734 |
0.302 |
|
| 2012 |
Seeger-Nukpezah T, Golemis EA. The extracellular matrix and ciliary signaling. Current Opinion in Cell Biology. 24: 652-61. PMID 22819513 DOI: 10.1016/J.Ceb.2012.06.002 |
0.338 |
|
| 2012 |
Seeger-Nukpezah T, Liebau MC, Höpker K, Lamkemeyer T, Benzing T, Golemis EA, Schermer B. The centrosomal kinase Plk1 localizes to the transition zone of primary cilia and induces phosphorylation of nephrocystin-1. Plos One. 7: e38838. PMID 22701722 DOI: 10.1371/Journal.Pone.0038838 |
0.373 |
|
| 2012 |
Plotnikova OV, Nikonova AS, Loskutov YV, Kozyulina PY, Pugacheva EN, Golemis EA. Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis. Molecular Biology of the Cell. 23: 2658-70. PMID 22621899 DOI: 10.1091/Mbc.E11-12-1056 |
0.37 |
|
| 2012 |
Dotan E, Meropol NJ, Zhu F, Zambito F, Bove B, Cai KQ, Godwin AK, Golemis EA, Astsaturov I, Cohen SJ. Relationship of increased aurora kinase A gene copy number, prognosis and response to chemotherapy in patients with metastatic colorectal cancer. British Journal of Cancer. 106: 748-55. PMID 22240781 DOI: 10.1038/Bjc.2011.587 |
0.301 |
|
| 2012 |
Ratushny V, Pathak HB, Beeharry N, Tikhmyanova N, Xiao F, Li T, Litwin S, Connolly DC, Yen TJ, Weiner LM, Godwin AK, Golemis EA. Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death. Oncogene. 31: 1217-27. PMID 21785464 DOI: 10.1038/Onc.2011.314 |
0.377 |
|
| 2012 |
Fidler CJ, Yang D, Zhu F, Mehra R, Astsaturov I, Ridge J, Golemis E, Burtness B. Abstract 721: Expression of Aurora A and Phospho-Aurora-A is predictive of survival in patients with head and neck cancer Cancer Research. 72: 721-721. DOI: 10.1158/1538-7445.Am2012-721 |
0.333 |
|
| 2012 |
Liu H, Serebriiskii I, Einarson MB, Pecherskaya A, Zhou Y, Pathak H, Godwin AK, Golemis EA. Abstract 276: Targeting signaling networks via RNAi to improve therapy for ovarian cancer Cancer Research. 72: 276-276. DOI: 10.1158/1538-7445.Am2012-276 |
0.375 |
|
| 2012 |
Serzhanova V, Little J, Izumchenko E, Seo S, Kurokawa M, Egleston B, Klein-Szanto A, Golemis E. Abstract P1-05-03: A requirement for neural precursor cell-expressed developmentally downregulated gene 9 during the initiation of mammary tumorigenesis in MMTV-neu mice Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P1-05-03 |
0.373 |
|
| 2011 |
Golemis EA, Serebriiskii I, Finley RL, Kolonin MG, Gyuris J, Brent R. Interaction trap/two-hybrid system to identify interacting proteins. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 17.3.. PMID 22161546 DOI: 10.1002/0471143030.Cb1703S53 |
0.399 |
|
| 2011 |
Mehra R, Serebriiskii IG, Dunbrack RL, Robinson MK, Burtness B, Golemis EA. Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 14: 260-79. PMID 21920801 DOI: 10.1016/J.Drup.2011.08.002 |
0.342 |
|
| 2011 |
Tikhmyanova N, Golemis EA. NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation. Plos One. 6: e22102. PMID 21765937 DOI: 10.1371/Journal.Pone.0022102 |
0.381 |
|
| 2011 |
Plotnikova OV, Pugacheva EN, Golemis EA. Aurora A kinase activity influences calcium signaling in kidney cells. The Journal of Cell Biology. 193: 1021-32. PMID 21670214 DOI: 10.1083/Jcb.201012061 |
0.346 |
|
| 2011 |
Li Y, Bavarva JH, Wang Z, Guo J, Qian C, Thibodeau SN, Golemis EA, Liu W. HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression. Oncogene. 30: 2633-43. PMID 21317929 DOI: 10.1038/Onc.2010.632 |
0.386 |
|
| 2010 |
Singh MK, Izumchenko E, Klein-Szanto AJ, Egleston BL, Wolfson M, Golemis EA. Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking NEDD9. Cancer Research. 70: 8907-16. PMID 20940402 DOI: 10.1158/0008-5472.Can-10-0353 |
0.373 |
|
| 2010 |
Astsaturov I, Ratushny V, Sukhanova A, Einarson MB, Bagnyukova T, Zhou Y, Devarajan K, Silverman JS, Tikhmyanova N, Skobeleva N, Pecherskaya A, Nasto RE, Sharma C, Jablonski SA, Serebriiskii IG, ... ... Golemis EA, et al. Synthetic lethal screen of an EGFR-centered network to improve targeted therapies. Science Signaling. 3: ra67. PMID 20858866 DOI: 10.1126/Scisignal.2001083 |
0.396 |
|
| 2010 |
Plotnikova OV, Pugacheva EN, Dunbrack RL, Golemis EA. Rapid calcium-dependent activation of Aurora-A kinase. Nature Communications. 1: 64. PMID 20842194 DOI: 10.1038/Ncomms1061 |
0.366 |
|
| 2010 |
Moore FE, Osmundson EC, Koblinski J, Pugacheva E, Golemis EA, Ray D, Kiyokawa H. The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation. Cell Division. 5: 22. PMID 20825672 DOI: 10.1186/1747-1028-5-22 |
0.447 |
|
| 2010 |
Tikhmyanova N, Tulin AV, Roegiers F, Golemis EA. Dcas supports cell polarization and cell-cell adhesion complexes in development. Plos One. 5: e12369. PMID 20808771 DOI: 10.1371/Journal.Pone.0012369 |
0.354 |
|
| 2010 |
Tikhmyanova N, Little JL, Golemis EA. CAS proteins in normal and pathological cell growth control. Cellular and Molecular Life Sciences : Cmls. 67: 1025-48. PMID 19937461 DOI: 10.1007/S00018-009-0213-1 |
0.368 |
|
| 2010 |
Dotan E, Meropol NJ, Zambito F, Bove B, Zhu F, Godwin AK, Golemis E, Cohen SJ, Astsaturov IA. Association of Aurora kinase A and epidermal growth factor receptor (EGFR) gene copy number with overall survival in KRAS wild-type patients with metastatic colorectal cancer. Journal of Clinical Oncology. 28: e14056-e14056. DOI: 10.1200/Jco.2010.28.15_Suppl.E14056 |
0.338 |
|
| 2010 |
Sukhanova AL, Bagnyukova T, Kratz LE, Kelley RI, Serebriiskii IG, Weiner LM, Golemis EA, Astsaturov IA. Abstract 5098: Targeting the cholesterol pathway geneSC4MOLsensitizes cancer to EGFR inhibitors Cancer Research. 70: 5098-5098. DOI: 10.1158/1538-7445.Am10-5098 |
0.335 |
|
| 2010 |
Little JL, Izumchenko E, Singh MK, Seo S, Kurokawa M, Egleston BL, Klein-Szanto A, Golemis EA. Abstract 3257: NEDD9 is required for initiation of HER2/Neu-dependent mammary tumor development Cancer Research. 70: 3257-3257. DOI: 10.1158/1538-7445.Am10-3257 |
0.341 |
|
| 2010 |
Nasto RE, Serebriiskii I, Jablonski SA, Johnson MD, Clarke R, Weiner LM, Golemis EA. Abstract 2014: An estrogen receptor - centered network for probing anti-estrogen drug resistance with siRNA screening technology Cancer Research. 70: 2014-2014. DOI: 10.1158/1538-7445.Am10-2014 |
0.334 |
|
| 2010 |
Pugacheva EN, McLaughlin S, Hindman B, Golemis EA. Abstract 1086: The role of HEF1 protein in stabilization and activation of AurA kinase in metastatic breast cancer Cancer Research. 70: 1086-1086. DOI: 10.1158/1538-7445.Am10-1086 |
0.418 |
|
| 2010 |
Weiner LM, Tang Y, Wang S, Surana R, Xu W, Zhou Y, Marks JD, Golemis E. Abstract PL6-2: Antibody-initiated cancer immunotherapy Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcme10-Pl6-2 |
0.318 |
|
| 2009 |
Plotnikova OV, Pugacheva EN, Golemis EA. Primary cilia and the cell cycle. Methods in Cell Biology. 94: 137-60. PMID 20362089 DOI: 10.1016/S0091-679X(08)94007-3 |
0.35 |
|
| 2009 |
Izumchenko E, Singh MK, Plotnikova OV, Tikhmyanova N, Little JL, Serebriiskii IG, Seo S, Kurokawa M, Egleston BL, Klein-Szanto A, Pugacheva EN, Hardy RR, Wolfson M, Connolly DC, Golemis EA. NEDD9 promotes oncogenic signaling in mammary tumor development. Cancer Research. 69: 7198-206. PMID 19738060 DOI: 10.1158/0008-5472.Can-09-0795 |
0.394 |
|
| 2009 |
Golemis EA, Serebriiskii I, Finley RL, Kolonin MG, Gyuris J, Brent R. Interaction trap/two-hybrid system to identify interacting proteins. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit19.2. PMID 19688737 DOI: 10.1002/0471140864.Ps1902S57 |
0.399 |
|
| 2009 |
Aquino JB, Lallemend F, Marmigère F, Adameyko II, Golemis EA, Ernfors P. The retinoic acid inducible Cas-family signaling protein Nedd9 regulates neural crest cell migration by modulating adhesion and actin dynamics. Neuroscience. 162: 1106-19. PMID 19464348 DOI: 10.1016/J.Neuroscience.2009.05.035 |
0.355 |
|
| 2009 |
Ratushny V, Astsaturov I, Burtness BA, Golemis EA, Silverman JS. Targeting EGFR resistance networks in head and neck cancer. Cellular Signalling. 21: 1255-68. PMID 19258037 DOI: 10.1016/J.Cellsig.2009.02.021 |
0.374 |
|
| 2009 |
Hopper-Borge EA, Nasto RE, Ratushny V, Weiner LM, Golemis EA, Astsaturov I. Mechanisms of tumor resistance to EGFR-targeted therapies. Expert Opinion On Therapeutic Targets. 13: 339-62. PMID 19236156 DOI: 10.1517/14712590902735795 |
0.302 |
|
| 2009 |
Singh MK, Izumchenko E, Klein‐Szanto AJ, Golemis EA. Abstract B106: Nedd9 null status initially delays mammary tumor growth, then selects for hyper‐aggressive mammary tumors Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B106 |
0.404 |
|
| 2008 |
Ratushny V, Golemis E. Resolving the network of cell signaling pathways using the evolving yeast two-hybrid system. Biotechniques. 44: 655-62. PMID 18474041 DOI: 10.2144/000112797 |
0.446 |
|
| 2008 |
Serebriiskii I, Castelló-Cros R, Lamb A, Golemis EA, Cukierman E. Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells. Matrix Biology : Journal of the International Society For Matrix Biology. 27: 573-85. PMID 18411046 DOI: 10.1016/J.Matbio.2008.02.008 |
0.341 |
|
| 2008 |
Plotnikova OV, Golemis EA, Pugacheva EN. Cell cycle-dependent ciliogenesis and cancer. Cancer Research. 68: 2058-61. PMID 18381407 DOI: 10.1158/0008-5472.Can-07-5838 |
0.377 |
|
| 2008 |
Singh MK, Dadke D, Nicolas E, Serebriiskii IG, Apostolou S, Canutescu A, Egleston BL, Golemis EA. A novel Cas family member, HEPL, regulates FAK and cell spreading. Molecular Biology of the Cell. 19: 1627-36. PMID 18256281 DOI: 10.1091/Mbc.E07-09-0953 |
0.351 |
|
| 2008 |
Singh M, Cowell L, Seo S, O'Neill G, Golemis E. Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle. Cell Biochemistry and Biophysics. 48: 54-72. PMID 17703068 DOI: 10.1007/S12013-007-0036-3 |
0.328 |
|
| 2007 |
Serebriiskii IG, Milech N, Golemis EA. A bacterial/yeast merged two-hybrid system: protocol for bacterial screening. Methods in Molecular Biology (Clifton, N.J.). 408: 291-315. PMID 18314589 DOI: 10.1007/978-1-59745-547-3_16 |
0.396 |
|
| 2007 |
Tikhmyanova NY, Izumchenko EA, Serebriiskii IG, Golemis EA. A bacterial/yeast merged two-hybrid system: protocol for yeast screening with single or parallel baits. Methods in Molecular Biology (Clifton, N.J.). 408: 257-90. PMID 18314588 DOI: 10.1007/978-1-59745-547-3_15 |
0.394 |
|
| 2007 |
Khazak V, Astsaturov I, Serebriiskii IG, Golemis EA. Selective Raf inhibition in cancer therapy. Expert Opinion On Therapeutic Targets. 11: 1587-609. PMID 18020980 DOI: 10.1517/14728222.11.12.1587 |
0.378 |
|
| 2007 |
O'Neill GM, Seo S, Serebriiskii IG, Lessin SR, Golemis EA. A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9. Cancer Research. 67: 8975-9. PMID 17908996 DOI: 10.1158/0008-5472.Can-07-1328 |
0.342 |
|
| 2007 |
Pugacheva EN, Jablonski SA, Hartman TR, Henske EP, Golemis EA. HEF1-dependent Aurora A activation induces disassembly of the primary cilium. Cell. 129: 1351-63. PMID 17604723 DOI: 10.1016/J.Cell.2007.04.035 |
0.388 |
|
| 2007 |
Skobeleva N, Menon S, Weber L, Golemis EA, Khazak V. In vitro and in vivo synergy of MCP compounds with mitogen-activated protein kinase pathway- and microtubule-targeting inhibitors. Molecular Cancer Therapeutics. 6: 898-906. PMID 17363484 DOI: 10.1158/1535-7163.Mct-06-0602 |
0.382 |
|
| 2007 |
Singh MK, Nicolas E, Gherraby W, Dadke D, Lessin S, Golemis EA. HEI10 negatively regulates cell invasion by inhibiting cyclin B/Cdk1 and other promotility proteins. Oncogene. 26: 4825-32. PMID 17297447 DOI: 10.1038/Sj.Onc.1210282 |
0.401 |
|
| 2007 |
Lee H, Kim D, Dan HC, Wu EL, Gritsko TM, Cao C, Nicosia SV, Golemis EA, Liu W, Coppola D, Brem SS, Testa JR, Cheng JQ. Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein. Molecular and Cellular Biology. 27: 2103-19. PMID 17210637 DOI: 10.1128/Mcb.00572-06 |
0.395 |
|
| 2007 |
Natarajan M, Stewart JE, Golemis EA, Pugacheva EN, Alexandropoulos K, Cox BD, Wang W, Grammer JR, Gladson CL. Erratum: HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells Oncogene. 26: 7282-7282. DOI: 10.1038/Sj.Onc.1210837 |
0.33 |
|
| 2007 |
Izumchenko E, Wolfson M, Golemis EA, Serebriiskii IG. 6 Yeast Hybrid Approaches Methods in Microbiology. 36: 103-137. DOI: 10.1016/S0580-9517(06)36006-0 |
0.401 |
|
| 2006 |
Pugacheva EN, Roegiers F, Golemis EA. Interdependence of cell attachment and cell cycle signaling. Current Opinion in Cell Biology. 18: 507-15. PMID 16919436 DOI: 10.1016/J.Ceb.2006.08.014 |
0.348 |
|
| 2006 |
Khazak V, Kato-Stankiewicz J, Tamanoi F, Golemis EA. Yeast screens for inhibitors of Ras-Raf interaction and characterization of MCP inhibitors of Ras-Raf interaction. Methods in Enzymology. 407: 612-29. PMID 16757356 DOI: 10.1016/S0076-6879(05)07048-5 |
0.306 |
|
| 2006 |
Grönholm M, Muranen T, Toby GG, Utermark T, Hanemann CO, Golemis EA, Carpén O. A functional association between merlin and HEI10, a cell cycle regulator. Oncogene. 25: 4389-98. PMID 16532029 DOI: 10.1038/Sj.Onc.1209475 |
0.793 |
|
| 2006 |
Pugacheva EN, Golemis EA. HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks. Cell Cycle (Georgetown, Tex.). 5: 384-91. PMID 16479169 DOI: 10.4161/Cc.5.4.2439 |
0.383 |
|
| 2006 |
Dadke D, Jarnik M, Pugacheva EN, Singh MK, Golemis EA. Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle. Molecular Biology of the Cell. 17: 1204-17. PMID 16394104 DOI: 10.1091/Mbc.E05-03-0237 |
0.362 |
|
| 2006 |
Natarajan M, Stewart JE, Golemis EA, Pugacheva EN, Alexandropoulos K, Cox BD, Wang W, Grammer JR, Gladson CL. HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene. 25: 1721-32. PMID 16288224 DOI: 10.1038/Sj.Onc.1209199 |
0.381 |
|
| 2005 |
Khazak V, Golemis EA, Weber L. Development of a yeast two-hybrid screen for selection of human Ras-Raf protein interaction inhibitors. Methods in Molecular Biology (Clifton, N.J.). 310: 253-71. PMID 16353379 DOI: 10.1007/978-1-59259-948-6_18 |
0.32 |
|
| 2005 |
Pugacheva EN, Golemis EA. The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. Nature Cell Biology. 7: 937-46. PMID 16184168 DOI: 10.1038/Ncb1309 |
0.394 |
|
| 2005 |
Serebriiskii IG, Fang R, Latypova E, Hopkins R, Vinson C, Joung JK, Golemis EA. A combined yeast/bacteria two-hybrid system: development and evaluation. Molecular & Cellular Proteomics : McP. 4: 819-26. PMID 15781424 DOI: 10.1074/Mcp.T500005-Mcp200 |
0.372 |
|
| 2004 |
Peterson JR, Golemis EA. Autoinhibited proteins as promising drug targets. Journal of Cellular Biochemistry. 93: 68-73. PMID 15352163 DOI: 10.1002/Jcb.20184 |
0.415 |
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| 2004 |
Sudomoina M, Latypova E, Favorova OO, Golemis EA, Serebriiskii IG. A gene expression system offering multiple levels of regulation: the Dual Drug Control (DDC) system. Bmc Biotechnology. 4: 9. PMID 15117411 DOI: 10.1186/1472-6750-4-9 |
0.332 |
|
| 2004 |
Einarson MB, Cukierman E, Compton DA, Golemis EA. Human enhancer of invasion-cluster, a coiled-coil protein required for passage through mitosis. Molecular and Cellular Biology. 24: 3957-71. PMID 15082789 DOI: 10.1128/Mcb.24.9.3957-3971.2004 |
0.353 |
|
| 2004 |
Cohen SJ, Palazzo I, Meropol NJ, Rogatko A, Weiner LM, Golemis EA, Cheng JD, Alpaugh RK. Fibroblast activation protein and focal adhesion kinase: novel stromal therapeutic targets in pancreatic adenocarcinoma Journal of Clinical Oncology. 22: 4094-4094. DOI: 10.1200/Jco.2004.22.90140.4094 |
0.367 |
|
| 2003 |
Na X, Duan HO, Messing EM, Schoen SR, Ryan CK, di Sant'Agnese PA, Golemis EA, Wu G. Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel-Lindau protein. The Embo Journal. 22: 4249-59. PMID 12912922 DOI: 10.1093/Emboj/Cdg410 |
0.387 |
|
| 2003 |
Zhang YZ, Cheng H, Gould KL, Golemis EA, Roder H. Structure, stability, and function of hDim1 investigated by NMR, circular dichroism, and mutational analysis Biochemistry. 42: 9609-9618. PMID 12911302 DOI: 10.1021/Bi034486I |
0.328 |
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| 2003 |
Toby GG, Gherraby W, Coleman TR, Golemis EA. A novel RING finger protein, human enhancer of invasion 10, alters mitotic progression through regulation of cyclin B levels. Molecular and Cellular Biology. 23: 2109-22. PMID 12612082 DOI: 10.1128/Mcb.23.6.2109-2122.2003 |
0.778 |
|
| 2003 |
Cai D, Felekkis KN, Near RI, O'Neill GM, van Seventer JM, Golemis EA, Lerner A. The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42. Journal of Immunology (Baltimore, Md. : 1950). 170: 969-78. PMID 12517963 DOI: 10.4049/Jimmunol.170.2.969 |
0.36 |
|
| 2002 |
Serebriiskii IG, Mitina O, Pugacheva EN, Benevolenskaya E, Kotova E, Toby GG, Khazak V, Kaelin WG, Chernoff J, Golemis EA. Detection of peptides, proteins, and drugs that selectively interact with protein targets. Genome Research. 12: 1785-91. PMID 12421766 DOI: 10.1101/Gr.450702 |
0.787 |
|
| 2002 |
Kato-Stankiewicz J, Hakimi I, Zhi G, Zhang J, Serebriiskii I, Guo L, Edamatsu H, Koide H, Menon S, Eckl R, Sakamuri S, Lu Y, Chen QZ, Agarwal S, Baumbach WR, ... Golemis EA, et al. Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 14398-403. PMID 12391290 DOI: 10.1073/Pnas.222222699 |
0.335 |
|
| 2002 |
Golemis EA, Tew KD, Dadke D. Protein interaction-targeted drug discovery: evaluating critical issues. Biotechniques. 32: 636-8, 640, 642 pass. PMID 11911666 DOI: 10.2144/02323Dd01 |
0.369 |
|
| 2002 |
Zawistowski JS, Serebriiskii IG, Lee MF, Golemis EA, Marchuk DA. KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis. Human Molecular Genetics. 11: 389-96. PMID 11854171 DOI: 10.1093/Hmg/11.4.389 |
0.411 |
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| 2002 |
Golemis EA, Ochs MF, Pugacheva EN. Signal transduction driving technology driving signal transduction: factors in the design of targeted therapies. Journal of Cellular Biochemistry. Supplement. 42-52. PMID 11842427 DOI: 10.1002/Jcb.10064 |
0.399 |
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| 2001 |
Reeder MK, Serebriiskii IG, Golemis EA, Chernoff J. Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42. The Journal of Biological Chemistry. 276: 40606-13. PMID 11514549 DOI: 10.1074/Jbc.M103925200 |
0.338 |
|
| 2001 |
van Seventer GA, Salmen HJ, Law SF, O'Neill GM, Mullen MM, Franz AM, Kanner SB, Golemis EA, van Seventer JM. Focal adhesion kinase regulates beta1 integrin-dependent T cell migration through an HEF1 effector pathway. European Journal of Immunology. 31: 1417-27. PMID 11465098 DOI: 10.1002/1521-4141(200105)31:5<1417::Aid-Immu1417>3.0.Co;2-C |
0.307 |
|
| 2001 |
Serebriiskii IG, Toby GG, Finley RL, Golemis EA. Genomic analysis utilizing the yeast two-hybrid system Methods in Molecular Biology (Clifton, N.J.). 175: 415-454. PMID 11462850 DOI: 10.1385/1-59259-235-X:415 |
0.731 |
|
| 2001 |
O'Neill GM, Golemis EA. Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. Molecular and Cellular Biology. 21: 5094-108. PMID 11438665 DOI: 10.1128/Mcb.21.15.5094-5108.2001 |
0.331 |
|
| 2001 |
Toby GG, Golemis EA. Using the yeast interaction trap and other two-hybrid-based approaches to study protein-protein interactions. Methods (San Diego, Calif.). 24: 201-17. PMID 11403570 DOI: 10.1006/Meth.2001.1182 |
0.776 |
|
| 2001 |
Toby GG, Golemis EA. Targeting proteins to specific cellular compartments to optimize physiological activity. Methods in Enzymology. 332: 77-87. PMID 11305119 DOI: 10.1016/S0076-6879(01)32193-6 |
0.784 |
|
| 2001 |
Serebriiskii IG, Mitina OV, Chernoff J, Golemis EA. Two-hybrid dual bait system to discriminate specificity of protein interactions in small GTPases. Methods in Enzymology. 332: 277-300. PMID 11305104 DOI: 10.1016/S0076-6879(01)32210-3 |
0.412 |
|
| 2001 |
Serebriiskii IG, Khazak V, Golemis EA. Redefinition of the yeast two-hybrid system in dialogue with changing priorities in biological research. Biotechniques. 30: 634-6, 638, 640 pas. PMID 11252799 DOI: 10.2144/01303Dd02 |
0.396 |
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| 2001 |
Fashena SJ, Serebriiskii IG, Golemis EA. LexA-based two-hybrid systems. Methods in Enzymology. 328: 14-26. PMID 11075335 DOI: 10.1016/S0076-6879(00)28387-0 |
0.361 |
|
| 2000 |
Liu X, Elia AE, Law SF, Golemis EA, Farley J, Wang T. A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1. The Embo Journal. 19: 6759-69. PMID 11118211 DOI: 10.1093/Emboj/19.24.6759 |
0.392 |
|
| 2000 |
Zhang Y, Lindblom T, Chang A, Sudol M, Sluder AE, Golemis EA. Evidence that dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for dim1 interactions with hnRNP F and Npw38/PQBP-1. Gene. 257: 33-43. PMID 11054566 DOI: 10.1016/S0378-1119(00)00372-3 |
0.408 |
|
| 2000 |
Serebriiskii IG, Golemis EA. Uses of lacZ to study gene function: evaluation of beta-galactosidase assays employed in the yeast two-hybrid system. Analytical Biochemistry. 285: 1-15. PMID 10998258 DOI: 10.1006/Abio.2000.4672 |
0.366 |
|
| 2000 |
Serebriiskii IG, Toby GG, Golemis EA. Streamlined yeast colorimetric reporter activity assays using scanners and plate readers. Biotechniques. 29: 278-9, 282-4, 286-8. PMID 10948429 DOI: 10.2144/00292St03 |
0.765 |
|
| 2000 |
Law SF, O'Neill GM, Fashena SJ, Einarson MB, Golemis EA. The docking protein HEF1 is an apoptotic mediator at focal adhesion sites. Molecular and Cellular Biology. 20: 5184-95. PMID 10866674 DOI: 10.1128/Mcb.20.14.5184-5195.2000 |
0.389 |
|
| 2000 |
Fashena SJ, Serebriiskii I, Golemis EA. The continued evolution of two-hybrid screening approaches in yeast: how to outwit different preys with different baits. Gene. 250: 1-14. PMID 10854774 DOI: 10.1016/S0378-1119(00)00182-7 |
0.405 |
|
| 2000 |
Serebriiskii I, Estojak J, Berman M, Golemis EA. Approaches to detecting false positives in yeast two-hybrid systems. Biotechniques. 28: 328-30, 332-6. PMID 10683744 DOI: 10.2144/00282Rr03 |
0.394 |
|
| 2000 |
O'Neill GM, Fashena SJ, Golemis EA. Integrin signalling: a new Cas(t) of characters enters the stage. Trends in Cell Biology. 10: 111-9. PMID 10675905 DOI: 10.1016/S0962-8924(99)01714-6 |
0.338 |
|
| 1999 |
Zhang YZ, Gould KL, Dunbrack RL JR, Cheng H, Roder H, Golemis EA. The evolutionarily conserved Dim1 protein defines a novel branch of the thioredoxin fold superfamily. Physiological Genomics. 1: 109-18. PMID 11015569 DOI: 10.1152/Physiolgenomics.1999.1.3.109 |
0.424 |
|
| 1999 |
Schaller S, Grandemange S, Shpakovski GV, Golemis EA, Kedinger C, Vigneron M. Interactions between the full complement of human RNA polymerase II subunits. Febs Letters. 461: 253-7. PMID 10567706 DOI: 10.1016/S0014-5793(99)01441-6 |
0.3 |
|
| 1999 |
Law SF, Zhang YZ, Fashena SJ, Toby G, Estojak J, Golemis EA. Dimerization of the docking/adaptor protein HEF1 via a carboxy-terminal helix-loop-helix domain. Experimental Cell Research. 252: 224-35. PMID 10502414 DOI: 10.1006/Excr.1999.4609 |
0.783 |
|
| 1999 |
Mitsuuchi Y, Johnson SW, Sonoda G, Tanno S, Golemis EA, Testa JR. Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2. Oncogene. 18: 4891-8. PMID 10490823 DOI: 10.1038/Sj.Onc.1203080 |
0.304 |
|
| 1999 |
Shen XQ, Bubulya A, Zhou XF, Khazak V, Golemis EA, Shemshedini L. Ligand-free RAR can interact with the RNA polymerase II subunit hsRPB7 and repress transcription. Endocrine. 10: 281-9. PMID 10484292 DOI: 10.1007/Bf02738627 |
0.339 |
|
| 1999 |
Serebriiskii I, Khazak V, Golemis EA. A two-hybrid dual bait system to discriminate specificity of protein interactions. The Journal of Biological Chemistry. 274: 17080-7. PMID 10358061 DOI: 10.1074/Jbc.274.24.17080 |
0.421 |
|
| 1999 |
Lin JH, Makris A, McMahon C, Bear SE, Patriotis C, Prasad VR, Brent R, Golemis EA, Tsichlis PN. The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1 Journal of Biological Chemistry. 274: 14706-14715. PMID 10329666 DOI: 10.1074/Jbc.274.21.14706 |
0.463 |
|
| 1999 |
Bellacosa A, Cicchillitti L, Schepis F, Riccio A, Yeung AT, Matsumoto Y, Golemis EA, Genuardi M, Neri G. MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1. Proceedings of the National Academy of Sciences of the United States of America. 96: 3969-74. PMID 10097147 DOI: 10.1073/Pnas.96.7.3969 |
0.322 |
|
| 1998 |
Petermann R, Mossier BM, Aryee DN, Khazak V, Golemis EA, Kovar H. Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II. Oncogene. 17: 603-10. PMID 9704926 DOI: 10.1038/Sj.Onc.1201964 |
0.371 |
|
| 1998 |
Law SF, Zhang YZ, Klein-Szanto AJ, Golemis EA. Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments. Molecular and Cellular Biology. 18: 3540-51. PMID 9584194 DOI: 10.1128/Mcb.18.6.3540 |
0.401 |
|
| 1998 |
Toby G, Law SF, Golemis EA. Vectors to target protein domains to different cellular compartments. Biotechniques. 24: 637-40. PMID 9564538 DOI: 10.2144/98244St05 |
0.779 |
|
| 1998 |
Khazak V, Estojak J, Cho H, Majors J, Sonoda G, Testa JR, Golemis EA. Analysis of the interaction of the novel RNA polymerase II (pol II) subunit hsRPB4 with its partner hsRPB7 and with pol II. Molecular and Cellular Biology. 18: 1935-45. PMID 9528765 DOI: 10.1128/Mcb.18.4.1935 |
0.318 |
|
| 1997 |
Astier A, Manié SN, Law SF, Canty T, Haghayghi N, Druker BJ, Salgia R, Golemis EA, Freedman AS. Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells. Leukemia & Lymphoma. 28: 65-72. PMID 9498705 DOI: 10.3109/10428199709058332 |
0.377 |
|
| 1997 |
Serebriiskii I, Estojak J, Sonoda G, Testa JR, Golemis EA. Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22. Oncogene. 15: 1043-9. PMID 9285558 DOI: 10.1038/Sj.Onc.1201268 |
0.399 |
|
| 1997 |
Wang B, Golemis EA, Kruh GD. ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks. The Journal of Biological Chemistry. 272: 17542-50. PMID 9211900 DOI: 10.1074/Jbc.272.28.17542 |
0.371 |
|
| 1997 |
Sattler M, Salgia R, Shrikhande G, Verma S, Uemura N, Law SF, Golemis EA, Griffin JD. Differential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1). The Journal of Biological Chemistry. 272: 14320-6. PMID 9162067 DOI: 10.1074/Jbc.272.22.14320 |
0.363 |
|
| 1997 |
Xiao GH, Shoarinejad F, Jin F, Golemis EA, Yeung RS. The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis Journal of Biological Chemistry. 272: 6097-6100. PMID 9045618 DOI: 10.1074/Jbc.272.10.6097 |
0.415 |
|
| 1997 |
Manié SN, Beck AR, Astier A, Law SF, Canty T, Hirai H, Druker BJ, Avraham H, Haghayeghi N, Sattler M, Salgia R, Griffin JD, Golemis EA, Freedman AS. Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells. The Journal of Biological Chemistry. 272: 4230-6. PMID 9020138 DOI: 10.1074/Jbc.272.7.4230 |
0.359 |
|
| 1996 |
Law SF, Estojak J, Wang B, Mysliwiec T, Kruh G, Golemis EA. Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Molecular and Cellular Biology. 16: 3327-37. PMID 8668148 DOI: 10.1128/Mcb.16.7.3327 |
0.446 |
|
| 1995 |
Datta K, Franke TF, Chan TO, Makris A, Yang SI, Kaplan DR, Morrison DK, Golemis EA, Tsichlis PN. AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation Molecular and Cellular Biology. 15: 2304-2310. PMID 7891724 DOI: 10.1128/Mcb.15.4.2304 |
0.347 |
|
| 1995 |
Khazak V, Sadhale PP, Woychik NA, Brent R, Golemis EA. Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology. Molecular Biology of the Cell. 6: 759-75. PMID 7579693 DOI: 10.1091/Mbc.6.7.759 |
0.322 |
|
| 1995 |
Estojak J, Brent R, Golemis EA. Correlation of two-hybrid affinity data with in vitro measurements. Molecular and Cellular Biology. 15: 5820-9. PMID 7565735 DOI: 10.1128/Mcb.15.10.5820 |
0.378 |
|
| 1994 |
Sato T, Hanada M, Bodrug S, Irie S, Iwama N, Boise LH, Thompson CB, Golemis E, Fong L, Wang HG. Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system. Proceedings of the National Academy of Sciences of the United States of America. 91: 9238-42. PMID 7937747 DOI: 10.1073/Pnas.91.20.9238 |
0.381 |
|
| 1993 |
Gyuris J, Golemis E, Chertkov H, Brent R. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell. 75: 791-803. PMID 8242750 DOI: 10.1016/0092-8674(93)90498-F |
0.413 |
|
| 1992 |
Golemis EA, Brent R. Fused protein domains inhibit DNA binding by LexA. Molecular and Cellular Biology. 12: 3006-14. PMID 1620111 DOI: 10.1128/Mcb.12.7.3006 |
0.355 |
|
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