Year |
Citation |
Score |
2024 |
Xu C, Zhang L, Zhou Y, Du H, Qi J, Tan F, Peng L, Gu X, Li N, Sun Q, Zhang Z, Lu Y, Qian X, Tong B, Sun J, ... Chai R, et al. Pcolce2 overexpression promotes supporting cell reprogramming in the neonatal mouse cochlea. Cell Proliferation. e13633. PMID 38528645 DOI: 10.1111/cpr.13633 |
0.462 |
|
2024 |
Hu Y, Xing J, Zhang H, Pang X, Zhai Y, Cheng H, Xu D, Liao M, Qi Y, Wu D, Zhang B, Cheng L, Chu B, Zhang C, Zhao Y, ... Chai R, et al. Electroacoustic responsive cochlea-on-a-chip. Advanced Materials (Deerfield Beach, Fla.). e2309002. PMID 38488690 DOI: 10.1002/adma.202309002 |
0.305 |
|
2024 |
Sun Q, Zhang L, Chen T, Li N, Tan F, Gu X, Zhou Y, Zhang Z, Lu Y, Lu J, Qian X, Guan B, Qi J, Ye F, Chai R. AAV-mediated Gpm6b expression supports hair cell reprogramming. Cell Proliferation. e13620. PMID 38400824 DOI: 10.1111/cpr.13620 |
0.53 |
|
2023 |
Ma X, Guo J, Tian M, Fu Y, Jiang P, Zhang Y, Chai R. Advance and Application of Single-cell Transcriptomics in Auditory Research. Neuroscience Bulletin. PMID 38015350 DOI: 10.1007/s12264-023-01149-z |
0.322 |
|
2023 |
Qi J, Huang W, Lu Y, Yang X, Zhou Y, Chen T, Wang X, Yu Y, Sun JQ, Chai R. Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear. Neuroscience Bulletin. PMID 37787875 DOI: 10.1007/s12264-023-01130-w |
0.512 |
|
2023 |
Cheng C, Qi J, Zhang L, Li H, Lu J, Li S, Zhang Z, Qiu Y, Zhang C, Jiang L, Yu C, Gao X, Bird PI, Chai R. Corrigendum to "Absence of Serpinb6a causes progressive hair cell apoptosis and hearing loss in mice" [Journal of Genetics and Genomics (2023) 50, 122-125]. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 50: 458. PMID 37330250 DOI: 10.1016/j.jgg.2023.04.011 |
0.301 |
|
2023 |
Cheng C, Ma J, Lu X, Zhang P, Wang X, Guo L, Li P, Wei Y, Li GL, Gao X, Zhang Y, Chai R, Li H, Sun S. P2X7 receptor is required for the ototoxicity caused by aminoglycoside in developing cochlear hair cells. Neurobiology of Disease. 106176. PMID 37263384 DOI: 10.1016/j.nbd.2023.106176 |
0.307 |
|
2023 |
Fu X, Wan P, Lu L, Wan Y, Liu Z, Hong G, Cao S, Bi X, Zhou J, Qiao R, Guo S, Xiao Y, Wang B, Chang M, Li W, ... ... Chai R, et al. Peroxisome Deficiency in Cochlear Hair Cells Causes Hearing Loss by Deregulating BK Channels. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2300402. PMID 37171794 DOI: 10.1002/advs.202300402 |
0.337 |
|
2023 |
Qian F, Wei G, Gao Y, Wang X, Gong J, Guo C, Wang X, Zhang X, Zhao J, Wang C, Xu M, Hu Y, Yin G, Kang J, Chai R, et al. Correction: Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss. Cellular and Molecular Life Sciences : Cmls. 80: 146. PMID 37169901 DOI: 10.1007/s00018-023-04780-1 |
0.392 |
|
2023 |
Yang X, Qi J, Zhang L, Tan F, Huang H, Xu C, Cui Y, Chai R, Wu P. The role of Espin in the stereocilia regeneration and protection in Atoh1-overexpressed cochlear epithelium. Cell Proliferation. e13483. PMID 37084708 DOI: 10.1111/cpr.13483 |
0.351 |
|
2023 |
Xu C, Qi J, Hu X, Zhang L, Sun Q, Li N, Chen X, Guo F, Wu P, Shi Y, Chai R. Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea. Cell Proliferation. e13458. PMID 36977657 DOI: 10.1111/cpr.13458 |
0.602 |
|
2023 |
Zhang L, Fang Y, Tan F, Guo F, Zhang Z, Li N, Sun Q, Qi J, Chai R. AAV-Net1 facilitates the trans-differentiation of supporting cells into hair cells in the murine cochlea. Cellular and Molecular Life Sciences : Cmls. 80: 86. PMID 36917323 DOI: 10.1007/s00018-023-04743-6 |
0.548 |
|
2022 |
Xia M, Ma J, Wu M, Guo L, Chen Y, Li GL, Sun S, Chai R, Li H, Li W. Generation of innervated cochlear organoid recapitulates early development of auditory unit. Stem Cell Reports. PMID 36584686 DOI: 10.1016/j.stemcr.2022.11.024 |
0.427 |
|
2022 |
Zhang Z, Gao S, Hu YN, Chen X, Cheng C, Fu XL, Zhang SS, Wang XL, Che YW, Zhang C, Chai RJ. Ti C T MXene Composite 3D Hydrogel Potentiates mTOR Signaling to Promote the Generation of Functional Hair Cells in Cochlea Organoids. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2203557. PMID 36117048 DOI: 10.1002/advs.202203557 |
0.463 |
|
2022 |
Cheng C, Qi J, Zhang L, Li H, Lu J, Li S, Zhang Z, Qiu Y, Zhang C, Jiang L, Yu C, Gao X, Bird PI, Chai R. Absence of Serpinb6a causes progressive hair cell apoptosis and hearing loss in mice. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 36087923 DOI: 10.1016/j.jgg.2022.08.006 |
0.367 |
|
2022 |
Li Y, Hu Y, Wei H, Cao W, Qi Y, Zhou S, Zhang P, Li H, Li GL, Chai R. Two-dimensional TiCT MXene promotes electrophysiological maturation of neural circuits. Journal of Nanobiotechnology. 20: 398. PMID 36045382 DOI: 10.1186/s12951-022-01590-8 |
0.314 |
|
2022 |
Wu Y, Meng W, Guan M, Zhao X, Zhang C, Fang Q, Zhang Y, Sun Z, Cai M, Huang D, Yang X, Yu Y, Cui Y, He S, Chai R. Pitavastatin protects against neomycin-induced ototoxicity through inhibition of endoplasmic reticulum stress. Frontiers in Molecular Neuroscience. 15: 963083. PMID 35992197 DOI: 10.3389/fnmol.2022.963083 |
0.423 |
|
2022 |
Zhang Z, Chai R. Hear the sounds: The role of G Protein-Coupled Receptors in the cochlea. American Journal of Physiology. Cell Physiology. PMID 35938679 DOI: 10.1152/ajpcell.00453.2021 |
0.347 |
|
2022 |
Ding X, Hu Y, Cheng H, Zhang X, Lu L, Gao S, Cheng C, Wang L, Qian X, Zhang C, Chai R, Gao X, Huang Z. Graphene Substrates Promote the Differentiation of Inner Ear Lgr5+ Progenitor Cells Into Hair Cells. Frontiers in Bioengineering and Biotechnology. 10: 927248. PMID 35814013 DOI: 10.3389/fbioe.2022.927248 |
0.453 |
|
2022 |
Qian F, Wei G, Gao Y, Wang X, Gong J, Guo C, Wang X, Zhang X, Zhao J, Wang C, Xu M, Hu Y, Yin G, Kang J, Chai R, et al. Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss. Cellular and Molecular Life Sciences : Cmls. 79: 385. PMID 35753015 DOI: 10.1007/s00018-022-04410-2 |
0.536 |
|
2022 |
Zhang Y, Zhang S, Zhou H, Ma X, Wu L, Tian M, Li S, Qian X, Gao X, Chai R. Dync1li1 is required for the survival of mammalian cochlear hair cells by regulating the transportation of autophagosomes. Plos Genetics. 18: e1010232. PMID 35727824 DOI: 10.1371/journal.pgen.1010232 |
0.358 |
|
2022 |
Xia L, Zhang C, Su K, Fan J, Niu Y, Yu Y, Chai R. Oriented Growth of Neural Stem Cell-Derived Neurons Regulated by Magnetic Nanochains. Frontiers in Bioengineering and Biotechnology. 10: 895107. PMID 35677297 DOI: 10.3389/fbioe.2022.895107 |
0.331 |
|
2022 |
Ma X, Zhang S, Qin S, Guo J, Yuan J, Qiang R, Zhou S, Cao W, Yang J, Ma F, Chai R. Transcriptomic and epigenomic analyses explore the potential role of H3K4me3 in neomycin-induced cochlear Lgr5+ progenitor cell regeneration of hair cells. Human Cell. PMID 35668241 DOI: 10.1007/s13577-022-00727-z |
0.562 |
|
2022 |
Zhang Q, Wu Y, Yu Y, Niu Y, Fang Q, Chen X, Qi J, Zhang C, Wu G, Su K, Chai R. Tetrandrine Prevents Neomycin-Induced Ototoxicity by Promoting Steroid Biosynthesis. Frontiers in Bioengineering and Biotechnology. 10: 876237. PMID 35519614 DOI: 10.3389/fbioe.2022.876237 |
0.331 |
|
2022 |
Zhang Y, Fang Q, Wang H, Qi J, Sun S, Liao M, Wu Y, Hu Y, Jiang P, Cheng C, Qian X, Tang M, Cao W, Xiang S, Zhang C, ... ... Chai R, et al. Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage. Autophagy. 1-17. PMID 35471096 DOI: 10.1080/15548627.2022.2062872 |
0.358 |
|
2022 |
Tao Y, Liu X, Yang L, Chu C, Tan F, Yu Z, Ke J, Li X, Zheng X, Zhao X, Qi J, Lin CP, Chai R, Zhong G, Wu H. AAV-ie-K558R mediated cochlear gene therapy and hair cell regeneration. Signal Transduction and Targeted Therapy. 7: 109. PMID 35449181 DOI: 10.1038/s41392-022-00938-8 |
0.511 |
|
2022 |
Li D, Hu Y, Wei H, Chen W, Liu Y, Yan X, Guo L, Liao M, Chen B, Chai R, Tang M. Superparamagnetic Iron Oxide Nanoparticles and Static Magnetic Field Regulate Neural Stem Cell Proliferation. Frontiers in Cellular Neuroscience. 15: 815280. PMID 35185472 DOI: 10.3389/fncel.2021.815280 |
0.307 |
|
2022 |
Wang M, Dong Y, Gao S, Zhong Z, Cheng C, Qiang R, Zhang Y, Shi X, Qian X, Gao X, Guan B, Yu C, Yu Y, Chai R. Hippo/YAP signaling pathway protects against neomycin-induced hair cell damage in the mouse cochlea. Cellular and Molecular Life Sciences : Cmls. 79: 79. PMID 35044530 DOI: 10.1007/s00018-021-04029-9 |
0.403 |
|
2021 |
He Z, Ding Y, Mu Y, Xu X, Kong W, Chai R, Chen X. Stem Cell-Based Therapies in Hearing Loss. Frontiers in Cell and Developmental Biology. 9: 730042. PMID 34746126 DOI: 10.3389/fcell.2021.730042 |
0.429 |
|
2021 |
Chen Y, Qiang R, Zhang Y, Cao W, Wu L, Jiang P, Ai J, Ma X, Dong Y, Gao X, Li H, Lu L, Zhang S, Chai R. The Expression and Roles of the Super Elongation Complex in Mouse Cochlear Lgr5+ Progenitor Cells. Frontiers in Cellular Neuroscience. 15: 735723. PMID 34658793 DOI: 10.3389/fncel.2021.735723 |
0.491 |
|
2021 |
Guo R, Liao M, Ma X, Hu Y, Qian X, Xiao M, Gao X, Chai R, Tang M. Cochlear implant-based electric-acoustic stimulation modulates neural stem cell-derived neural regeneration. Journal of Materials Chemistry. B. 9: 7793-7804. PMID 34586130 DOI: 10.1039/d1tb01029h |
0.331 |
|
2021 |
Cheng C, Hou Y, Zhang Z, Wang Y, Lu L, Zhang L, Jiang P, Gao S, Fang Q, Zhu C, Gao J, Liu X, Xie W, Jia Z, Xu Z, ... ... Chai R, et al. Disruption of the autism-related gene Pak1 causes stereocilia disorganization, hair cell loss, and deafness in mice. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 34049799 DOI: 10.1016/j.jgg.2021.03.010 |
0.316 |
|
2021 |
He ZH, Li M, Fang QJ, Liao FL, Zou SY, Wu X, Sun HY, Zhao XY, Hu YJ, Xu XX, Chen S, Sun Y, Chai RJ, Kong WJ. FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway. Autophagy. 1-22. PMID 34006186 DOI: 10.1080/15548627.2021.1916194 |
0.321 |
|
2021 |
Chen Y, Gu Y, Li Y, Li GL, Chai R, Li W, Li H. Generation of mature and functional hair cells by co-expression of Gfi1, Pou4f3, and Atoh1 in the postnatal mouse cochlea. Cell Reports. 35: 109016. PMID 33882317 DOI: 10.1016/j.celrep.2021.109016 |
0.361 |
|
2021 |
Yuan TF, Dong Y, Zhang L, Qi J, Yao C, Wang Y, Chai R, Liu Y, So KF. Neuromodulation-Based Stem Cell Therapy in Brain Repair: Recent Advances and Future Perspectives. Neuroscience Bulletin. PMID 33871821 DOI: 10.1007/s12264-021-00667-y |
0.373 |
|
2020 |
Guo R, Xiao M, Zhao W, Zhou S, Hu Y, Liao M, Wang S, Yang X, Chai R, Tang M. 2D TiCT MXene couples electrical stimulation to promote proliferation and neural differentiation of neural stem cells. Acta Biomaterialia. PMID 33348061 DOI: 10.1016/j.actbio.2020.12.035 |
0.343 |
|
2020 |
Ding Y, Meng W, Kong W, He Z, Chai R. The Role of FoxG1 in the Inner Ear. Frontiers in Cell and Developmental Biology. 8: 614954. PMID 33344461 DOI: 10.3389/fcell.2020.614954 |
0.355 |
|
2020 |
Zhou H, Qian X, Xu N, Zhang S, Zhu G, Zhang Y, Liu D, Cheng C, Zhu X, Liu Y, Lu L, Tang J, Chai R, Gao X. Disruption of Atg7-dependent autophagy causes electromotility disturbances, outer hair cell loss, and deafness in mice. Cell Death & Disease. 11: 913. PMID 33099575 DOI: 10.1038/s41419-020-03110-8 |
0.333 |
|
2020 |
Zhang Y, Zhang S, Zhang Z, Dong Y, Ma X, Qiang R, Chen Y, Gao X, Zhao C, Chen F, He S, Chai R. Knockdown of in Sox9+ supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse utricle. Aging. 12. PMID 33099273 DOI: 10.18632/aging.104009 |
0.386 |
|
2020 |
Qian F, Wang X, Yin Z, Xie G, Yuan H, Liu D, Chai R. The gene is required for hair cell development in zebrafish. Aging. 12. PMID 33044947 DOI: 10.18632/aging.103840 |
0.354 |
|
2020 |
Zhong Z, Fu X, Li H, Chen J, Wang M, Gao S, Zhang L, Cheng C, Zhang Y, Li P, Zhang S, Qian X, Shu Y, Chai R, Gao X. Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage. Frontiers in Cell and Developmental Biology. 8: 712. PMID 32984303 DOI: 10.3389/fcell.2020.00712 |
0.328 |
|
2020 |
Xia L, Shang Y, Chen X, Li H, Xu X, Liu W, Yang G, Wang T, Gao X, Chai R. Oriented Neural Spheroid Formation and Differentiation of Neural Stem Cells Guided by Anisotropic Inverse Opals. Frontiers in Bioengineering and Biotechnology. 8: 848. PMID 32850719 DOI: 10.3389/Fbioe.2020.00848 |
0.474 |
|
2020 |
Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Sun C, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D. THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. Plos Genetics. 16: e1008953. PMID 32776944 DOI: 10.1371/Journal.Pgen.1008953 |
0.49 |
|
2020 |
Yang Y, Zhang Y, Chai R, Gu Z. A Polydopamine-Functionalized Carbon Microfibrous Scaffold Accelerates the Development of Neural Stem Cells. Frontiers in Bioengineering and Biotechnology. 8: 616. PMID 32714901 DOI: 10.3389/Fbioe.2020.00616 |
0.473 |
|
2020 |
Zhang S, Qiang R, Dong Y, Zhang Y, Chen Y, Zhou H, Gao X, Chai R. Hair cell regeneration from inner ear progenitors in the mammalian cochlea. American Journal of Stem Cells. 9: 25-35. PMID 32699655 |
0.517 |
|
2020 |
Qi J, Zhang L, Tan F, Liu Y, Chu C, Zhu W, Wang Y, Qi Z, Chai R. Espin distribution as revealed by super-resolution microscopy of stereocilia. American Journal of Translational Research. 12: 130-141. PMID 32051742 |
0.343 |
|
2019 |
Li D, Yan X, Hu Y, Liu Y, Guo R, Liao M, Shao B, Tang Q, Guo X, Chai R, Zhang Q, Tang M. Two-Photon Image Tracking of Neural Stem Cells via Iridium Complexes Encapsulated in Polymeric Nanospheres. Acs Biomaterials Science & Engineering. 5: 1561-1568. PMID 33405629 DOI: 10.1021/Acsbiomaterials.8B01231 |
0.395 |
|
2019 |
Gao S, Cheng C, Wang M, Jiang P, Zhang L, Wang Y, Wu H, Zeng X, Wang H, Gao X, Ma Y, Chai R. Blebbistatin Inhibits Neomycin-Induced Apoptosis in Hair Cell-Like HEI-OC-1 Cells and in Cochlear Hair Cells. Frontiers in Cellular Neuroscience. 13: 590. PMID 32116554 DOI: 10.3389/Fncel.2019.00590 |
0.48 |
|
2019 |
Fang Q, Zhang Y, Chen X, Li H, Cheng L, Zhu W, Zhang Z, Tang M, Liu W, Wang H, Wang T, Shen T, Chai R. Three-Dimensional Graphene Enhances Neural Stem Cell Proliferation Through Metabolic Regulation. Frontiers in Bioengineering and Biotechnology. 7: 436. PMID 31998703 DOI: 10.3389/Fbioe.2019.00436 |
0.429 |
|
2019 |
Mei H, Mei D, Yu H, Sun S, Chen Y, Zhang Y, Chai R, Li H. Increased mitochondrial DNA copy number protects hair cells and HEI‑OC1 cells against drug‑induced apoptosis. Molecular Medicine Reports. PMID 31939628 DOI: 10.3892/Mmr.2019.10838 |
0.444 |
|
2019 |
Cheng C, Wang Y, Guo L, Lu X, Zhu W, Muhammad W, Zhang L, Lu L, Gao J, Tang M, Chen F, Gao X, Li H, Chai R. Age-related transcriptome changes in Sox2+ supporting cells in the mouse cochlea. Stem Cell Research & Therapy. 10: 365. PMID 31791390 DOI: 10.1186/S13287-019-1437-0 |
0.476 |
|
2019 |
Zhang Y, Li W, He Z, Wang Y, Shao B, Cheng C, Zhang S, Tang M, Qian X, Kong W, Wang H, Chai R, Gao X. Pre-treatment With Fasudil Prevents Neomycin-Induced Hair Cell Damage by Reducing the Accumulation of Reactive Oxygen Species. Frontiers in Molecular Neuroscience. 12: 264. PMID 31780893 DOI: 10.3389/Fnmol.2019.00264 |
0.468 |
|
2019 |
Fang QJ, Wu F, Chai R, Sha SH. Cochlear Surface Preparation in the Adult Mouse. Journal of Visualized Experiments : Jove. PMID 31762458 DOI: 10.3791/60299 |
0.562 |
|
2019 |
He ZH, Zou SY, Li M, Liao FL, Wu X, Sun HY, Zhao XY, Hu YJ, Li D, Xu XX, Chen S, Sun Y, Chai RJ, Kong WJ. The nuclear transcription factor FoxG1 affects the sensitivity of mimetic aging hair cells to inflammation by regulating autophagy pathways. Redox Biology. 28: 101364. PMID 31731101 DOI: 10.1016/J.Redox.2019.101364 |
0.469 |
|
2019 |
Zhang S, Zhang Y, Dong Y, Guo L, Zhang Z, Shao B, Qi J, Zhou H, Zhu W, Yan X, Hong G, Zhang L, Zhang X, Tang M, Zhao C, ... ... Chai R, et al. Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea. Cellular and Molecular Life Sciences : Cmls. PMID 31485717 DOI: 10.1007/s00018-019-03291-2 |
0.398 |
|
2019 |
Li G, Chen K, You D, Xia M, Li W, Fan S, Chai R, Zhang Y, Li H, Sun S. Laminin-Coated Electrospun Regenerated Silk Fibroin Mats Promote Neural Progenitor Cell Proliferation, Differentiation, and Survival . Frontiers in Bioengineering and Biotechnology. 7: 190. PMID 31448271 DOI: 10.3389/Fbioe.2019.00190 |
0.428 |
|
2019 |
Zhang S, Liu D, Dong Y, Zhang Z, Zhang Y, Zhou H, Guo L, Qi J, Qiang R, Tang M, Gao X, Zhao C, Chen X, Qian X, Chai R. Frizzled-9+ Supporting Cells Are Progenitors for the Generation of Hair Cells in the Postnatal Mouse Cochlea. Frontiers in Molecular Neuroscience. 12: 184. PMID 31427926 DOI: 10.3389/Fnmol.2019.00184 |
0.626 |
|
2019 |
Tan F, Chu C, Qi J, Li W, You D, Li K, Chen X, Zhao W, Cheng C, Liu X, Qiao Y, Su B, He S, Zhong C, Li H, ... Chai R, et al. AAV-ie enables safe and efficient gene transfer to inner ear cells. Nature Communications. 10: 3733. PMID 31427575 DOI: 10.1038/S41467-019-11687-8 |
0.391 |
|
2019 |
Zhao J, Tang M, Cao J, Ye D, Guo X, Xi J, Zhou Y, Xia Y, Qiao J, Chai R, Yang X, Kang J. Structurally Tunable Reduced Graphene Oxide Substrate Maintains Mouse Embryonic Stem Cell Pluripotency. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1802136. PMID 31380157 DOI: 10.1002/advs.201802136 |
0.36 |
|
2019 |
Tang M, Li J, He L, Guo R, Yan X, Li D, Zhang Y, Liao M, Shao B, Hu Y, Liu Y, Tang Q, Xia L, Guo X, Chai R. Transcriptomic profiling of neural stem cell differentiation on graphene substrates. Colloids and Surfaces. B, Biointerfaces. 182: 110324. PMID 31288132 DOI: 10.1016/J.Colsurfb.2019.06.054 |
0.378 |
|
2019 |
Wang J, Shen J, Guo L, Cheng C, Chai R, Shu Y, Li H. A humanized mouse model, demonstrating progressive hearing loss caused by MYO6 p.C442Y, is inherited in a semi-dominant pattern. Hearing Research. 379: 79-88. PMID 31103816 DOI: 10.1016/J.Heares.2019.04.014 |
0.384 |
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2019 |
Liu Y, Qi J, Chen X, Tang M, Chu C, Zhu W, Li H, Tian C, Yang G, Zhong C, Zhang Y, Ni G, He S, Chai R, Zhong G. Critical role of spectrin in hearing development and deafness. Science Advances. 5: eaav7803. PMID 31001589 DOI: 10.1126/Sciadv.Aav7803 |
0.388 |
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2019 |
Guo J, Chai R, Li H, Sun S. Protection of Hair Cells from Ototoxic Drug-Induced Hearing Loss. Advances in Experimental Medicine and Biology. 1130: 17-36. PMID 30915699 DOI: 10.1007/978-981-13-6123-4_2 |
0.444 |
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2019 |
Chen Y, Zhang S, Chai R, Li H. Hair Cell Regeneration. Advances in Experimental Medicine and Biology. 1130: 1-16. PMID 30915698 DOI: 10.1007/978-981-13-6123-4_1 |
0.611 |
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2019 |
Fang Q, Zhang Y, Da P, Shao B, Pan H, He Z, Cheng C, Li D, Guo J, Wu X, Guan M, Liao M, Zhang Y, Sha S, Zhou Z, ... ... Chai R, et al. Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Scientific Reports. 9: 3357. PMID 30833597 DOI: 10.1038/S41598-019-39769-Z |
0.398 |
|
2019 |
Gu X, Chai R, Guo L, Dong B, Li W, Shu Y, Huang X, Li H. Transduction of Adeno-Associated Virus Vectors Targeting Hair Cells and Supporting Cells in the Neonatal Mouse Cochlea. Frontiers in Cellular Neuroscience. 13: 8. PMID 30733670 DOI: 10.3389/Fncel.2019.00008 |
0.543 |
|
2018 |
Li A, You D, Li W, Cui Y, He Y, Li W, Chen Y, Feng X, Sun S, Chai R, Li H. Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2. Drug Delivery. 25: 1033-1043. PMID 30799660 DOI: 10.1080/10717544.2018.1461277 |
0.385 |
|
2018 |
Chai R, Li GL, Wang J, Huang H. Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells 2018. Neural Plasticity. 2018: 4759135. PMID 30647730 DOI: 10.1155/2018/4759135 |
0.465 |
|
2018 |
Xie Y, Wang D, Lan F, Wei G, Ni T, Chai R, Liu D, Hu S, Li M, Li D, Wang H, Wang Y. Author Correction: An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells. Scientific Reports. 8: 17900. PMID 30538257 DOI: 10.1038/S41598-018-36738-W |
0.343 |
|
2018 |
He Z, Fang Q, Li H, Shao B, Zhang Y, Zhang Y, Han X, Guo R, Cheng C, Guo L, Shi L, Li A, Yu C, Kong W, Zhao C, ... ... Chai R, et al. The role of FOXG1 in the postnatal development and survival of mouse cochlear hair cells. Neuropharmacology. PMID 30336149 DOI: 10.1016/j.neuropharm.2018.10.021 |
0.315 |
|
2018 |
Zhu C, Cheng C, Wang Y, Muhammad W, Liu S, Zhu W, Shao B, Zhang Z, Yan X, He Q, Xu Z, Yu C, Qian X, Lu L, Zhang S, ... ... Chai R, et al. Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice. Frontiers in Molecular Neuroscience. 11: 362. PMID 30333726 DOI: 10.3389/Fnmol.2018.00362 |
0.456 |
|
2018 |
Fu X, Sun X, Zhang L, Jin Y, Chai R, Yang L, Zhang A, Liu X, Bai X, Li J, Wang H, Gao J. Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss. The Journal of Clinical Investigation. PMID 30247156 DOI: 10.1172/Jci98058 |
0.473 |
|
2018 |
Yu Z, Jiang K, Xu Z, Huang H, Qian N, Lu Z, Chen D, Di R, Yuan T, Du Z, Xie W, Lu X, Li H, Chai R, Yang Y, et al. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration. Cell Stem Cell. PMID 30122476 DOI: 10.1016/J.Stem.2018.07.016 |
0.525 |
|
2018 |
Li H, Song Y, He Z, Chen X, Wu X, Li X, Bai X, Liu W, Li B, Wang S, Han Y, Xu L, Zhang D, Li J, Chai R, et al. Meclofenamic Acid Reduces Reactive Oxygen Species Accumulation and Apoptosis, Inhibits Excessive Autophagy, and Protects Hair Cell-Like HEI-OC1 Cells From Cisplatin-Induced Damage. Frontiers in Cellular Neuroscience. 12: 139. PMID 29875633 DOI: 10.3389/Fncel.2018.00139 |
0.453 |
|
2018 |
Zhang Y, Guo L, Lu X, Cheng C, Sun S, Li W, Zhao L, Lai C, Zhang S, Yu C, Tang M, Chen Y, Chai R, Li H. Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea. Frontiers in Molecular Neuroscience. 11: 147. PMID 29867341 DOI: 10.3389/Fnmol.2018.00147 |
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You D, Guo L, Li W, Sun S, Chen Y, Chai R, Li H. Characterization of Wnt and Notch-Responsive Lgr5+ Hair Cell Progenitors in the Striolar Region of the Neonatal Mouse Utricle. Frontiers in Molecular Neuroscience. 11: 137. PMID 29760650 DOI: 10.3389/Fnmol.2018.00137 |
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Liu W, Xu X, Fan Z, Sun G, Han Y, Zhang D, Xu L, Wang M, Wang X, Zhang S, Tang M, Li J, Chai R, Wang H. Wnt signaling activates TIGAR and protects against cisplatin-induced spiral ganglion neuron damage in the mouse cochlea. Antioxidants & Redox Signaling. PMID 29587485 DOI: 10.1089/Ars.2017.7288 |
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Chen Y, Lu X, Guo L, Ni W, Zhang Y, Zhao L, Wu L, Sun S, Zhang S, Tang M, Li W, Chai R, Li H. Hedgehog Signaling Promotes the Proliferation and Subsequent Hair Cell Formation of Progenitor Cells in the Neonatal Mouse Cochlea. Frontiers in Molecular Neuroscience. 10: 426. PMID 29311816 DOI: 10.3389/Fnmol.2017.00426 |
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Wang Y, Li J, Yao X, Li W, Du H, Tang M, Xiong W, Chai R, Xu Z. Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice. Frontiers in Molecular Neuroscience. 10: 401. PMID 29255404 DOI: 10.3389/Fnmol.2017.00401 |
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He Y, Lu X, Qian F, Liu D, Chai R, Li H. Insm1a Is Required for Zebrafish Posterior Lateral Line Development. Frontiers in Molecular Neuroscience. 10: 241. PMID 28824372 DOI: 10.3389/Fnmol.2017.00241 |
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Pan H, Song Q, Huang Y, Wang J, Chai R, Yin S, Wang J. Auditory Neuropathy after Damage to Cochlear Spiral Ganglion Neurons in Mice Resulting from Conditional Expression of Diphtheria Toxin Receptors. Scientific Reports. 7: 6409. PMID 28743950 DOI: 10.1038/S41598-017-06600-6 |
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Chen Q, Quan Y, Wang N, Xie C, Ji Z, He H, Chai R, Li H, Yin S, Chin YE, Wei X, Gao WQ. Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea. Stem Cell Reports. PMID 28669599 DOI: 10.1016/J.Stemcr.2017.05.031 |
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Waqas M, Sun S, Xuan C, Fang Q, Zhang X, Islam IU, Qi J, Zhang S, Gao X, Tang M, Shi H, Li H, Chai R. Bone morphogenetic protein 4 promotes the survival and preserves the structure of flow-sorted Bhlhb5+ cochlear spiral ganglion neurons in vitro. Scientific Reports. 7: 3506. PMID 28615657 DOI: 10.1038/S41598-017-03810-W |
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Xie Y, Wang D, Lan F, Wei G, Ni T, Chai R, Liu D, Hu S, Li M, Li D, Wang H, Wang Y. An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells. Scientific Reports. 7: 2320. PMID 28539611 DOI: 10.1038/S41598-017-02456-Y |
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Chai R, Li GL, Wang J, Zou J. Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells. Neural Plasticity. 2017: 1807581. PMID 28316840 DOI: 10.1155/2017/1807581 |
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Yan W, Liu W, Qi J, Fang Q, Fan Z, Sun G, Han Y, Zhang D, Xu L, Wang M, Li J, Chen F, Liu D, Chai R, Wang H. A Three-Dimensional Culture System with Matrigel Promotes Purified Spiral Ganglion Neuron Survival and Function In Vitro. Molecular Neurobiology. PMID 28283883 DOI: 10.1007/S12035-017-0471-0 |
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Yu X, Liu W, Fan Z, Qian F, Zhang D, Han Y, Xu L, Sun G, Qi J, Zhang S, Tang M, Li J, Chai R, Wang H. c-Myb knockdown increases the neomycin-induced damage to hair-cell-like HEI-OC1 cells in vitro. Scientific Reports. 7: 41094. PMID 28112219 DOI: 10.1038/Srep41094 |
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Wang X, Yuan W, Wang X, Qi J, Qin Y, Shi Y, Zhang J, Gong J, Dong Z, Liu X, Sun C, Chai R, Le Noble F, Liu D. The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis. Oncotarget. PMID 27780917 DOI: 10.18632/Oncotarget.12793 |
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Li Y, Li A, Wu J, He Y, Yu H, Chai R, Li H. MiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a. Cell Death & Disease. 7: e2362. PMID 27607577 DOI: 10.1038/Cddis.2016.246 |
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Guo R, Zhang S, Xiao M, Qian F, He Z, Li D, Zhang X, Li H, Yang X, Wang M, Chai R, Tang M. Accelerating bioelectric functional development of neural stem cells by graphene coupling: Implications for neural interfacing with conductive materials. Biomaterials. 106: 193-204. PMID 27566868 DOI: 10.1016/J.Biomaterials.2016.08.019 |
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Wu J, Li W, Lin C, Chen Y, Cheng C, Sun S, Tang M, Chai R, Li H. Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles. Scientific Reports. 6: 29418. PMID 27435629 DOI: 10.1038/Srep29418 |
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Tang D, Lin Q, He Y, Chai R, Li H. Inhibition of H3K9me2 Reduces Hair Cell Regeneration after Hair Cell Loss in the Zebrafish Lateral Line by Down-Regulating the Wnt and Fgf Signaling Pathways. Frontiers in Molecular Neuroscience. 9: 39. PMID 27303264 DOI: 10.3389/Fnmol.2016.00039 |
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He Y, Wang Z, Sun S, Tang D, Li W, Chai R, Li H. HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish. Molecular Neurobiology. PMID 26395281 DOI: 10.1007/S12035-015-9433-6 |
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He Y, Tang D, Cai C, Chai R, Li H. LSD1 is Required for Hair Cell Regeneration in Zebrafish. Molecular Neurobiology. PMID 26008620 DOI: 10.1007/S12035-015-9206-2 |
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Wang X, Wang X, Yuan W, Chai R, Liu D. Egfl6 is involved in zebrafish notochord development. Fish Physiology and Biochemistry. 41: 961-9. PMID 25952972 DOI: 10.1007/S10695-015-0061-X |
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Mei H, Sun S, Bai Y, Chen Y, Chai R, Li H. Reduced mtDNA copy number increases the sensitivity of tumor cells to chemotherapeutic drugs. Cell Death & Disease. 6: e1710. PMID 25837486 DOI: 10.1038/Cddis.2015.78 |
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Li W, Wu J, Yang J, Sun S, Chai R, Chen ZY, Li H. Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway. Proceedings of the National Academy of Sciences of the United States of America. 112: 166-71. PMID 25535395 DOI: 10.1073/Pnas.1415901112 |
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Shaikh S, Rehman FU, Du T, Jiang H, Yin L, Wang X, Chai R. Real-time Multimodal Bioimaging of Cancer Cells and Exosomes through Biosynthesized Iridium and Iron Nanoclusters. Acs Applied Materials & Interfaces. PMID 30011179 DOI: 10.1021/Acsami.8B08975 |
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Qi J, Liu Y, Chu C, Chen X, Zhu W, Shu Y, He S, Chai R, Zhong G. A cytoskeleton structure revealed by super-resolution fluorescence imaging in inner ear hair cells. Cell Discovery. 5: 12. PMID 30792888 DOI: 10.1038/S41421-018-0076-4 |
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2016 |
Sun G, Liu W, Fan Z, Zhang D, Han Y, Xu L, Qi J, Zhang S, Gao BT, Bai X, Li J, Chai R, Wang H. The Three-Dimensional Culture System with Matrigel and Neurotrophic Factors Preserves the Structure and Function of Spiral Ganglion Neuron In Vitro. Neural Plasticity. 2016: 4280407. PMID 27057364 DOI: 10.1155/2016/4280407 |
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2021 |
Zhang S, Dong Y, Qiang R, Zhang Y, Zhang X, Chen Y, Jiang P, Ma X, Wu L, Ai J, Gao X, Wang P, Chen J, Chai R. Characterization of Expression in Mouse Cochlear Hair Cells. Frontiers in Genetics. 12: 625867. PMID 33889175 DOI: 10.3389/fgene.2021.625867 |
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Sun G, Zheng Y, Fu X, Zhang W, Ren J, Ma S, Sun S, He X, Wang Q, Ji Z, Cheng F, Yan K, Liu Z, Belmonte JCI, Qu J, ... ... Chai R, et al. Single-cell transcriptomic atlas of mouse cochlear aging. Protein & Cell. PMID 36933008 DOI: 10.1093/procel/pwac058 |
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2022 |
Fu X, Li P, Zhang L, Song Y, An Y, Zhang A, Liu W, Ye C, Zhang Y, Yue R, Sun X, Chai R, Wang H, Gao J. Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss. Proceedings of the National Academy of Sciences of the United States of America. 119: e2107357119. PMID 35238644 DOI: 10.1073/pnas.2107357119 |
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2023 |
Qi J, Tan F, Zhang L, Zhou Y, Zhang Z, Sun Q, Li N, Fang Y, Chen X, Wu Y, Zhong G, Chai R. Critical role of TPRN rings in the stereocilia for hearing. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 37952086 DOI: 10.1016/j.ymthe.2023.11.011 |
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Lv J, Fu X, Li Y, Hong G, Li P, Lin J, Xun Y, Fang L, Weng W, Yue R, Li GL, Guan B, Li H, Huang Y, Chai R. Deletion of in Mice Does Not Alter Auditory Function. Frontiers in Cell and Developmental Biology. 9: 630361. PMID 33693002 DOI: 10.3389/fcell.2021.630361 |
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2020 |
Lin JY, Cheng J, Du YQ, Pan W, Zhang Z, Wang J, An J, Yang F, Xu YF, Lin H, An WT, Wang J, Yang Z, Chai RJ, Sha XY, et al. In vitro expansion of pancreatic islet clusters facilitated by hormones and chemicals. Cell Discovery. 6: 20. PMID 32284878 DOI: 10.1038/S41421-020-0159-X |
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2022 |
Bu C, Xu L, Han Y, Wang M, Wang X, Liu W, Chai R, Wang H. c-Myb protects cochlear hair cells from cisplatin-induced damage via the PI3K/Akt signaling pathway. Cell Death Discovery. 8: 78. PMID 35210433 DOI: 10.1038/s41420-022-00879-9 |
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2019 |
Wang Y, Li Q, Liu L, Zhou Z, Ruan Z, Kong L, Li Y, Wang Y, Zhong N, Chai R, Luo X, Guo Y, Hawrylycz M, Luo Q, Gu Z, et al. TeraVR empowers precise reconstruction of complete 3-D neuronal morphology in the whole brain. Nature Communications. 10: 3474. PMID 31375678 DOI: 10.1038/S41467-019-11443-Y |
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2016 |
Wang X, Ling CC, Li L, Qin Y, Qi J, Liu X, You B, Shi Y, Zhang J, Jiang Q, Xu H, Sun C, You Y, Chai R, Liu D. MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis. Cardiovascular Research. PMID 26825552 DOI: 10.1093/Cvr/Cvw023 |
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2021 |
Fu X, An Y, Wang H, Li P, Lin J, Yuan J, Yue R, Jin Y, Gao J, Chai R. Deficiency of Klc2 Induces Low-Frequency Sensorineural Hearing Loss in C57BL/6 J Mice and Human. Molecular Neurobiology. PMID 34014435 DOI: 10.1007/s12035-021-02422-w |
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2023 |
Liu D, Liang CH, Huang B, Zhuang X, Cui W, Yang L, Yang Y, Zhang Y, Fu X, Zhang X, Du L, Gu W, Wang X, Yin C, Chai R, et al. Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2204006. PMID 36627132 DOI: 10.1002/advs.202204006 |
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Liao M, Cui Q, Hu Y, Xing J, Wu D, Zheng S, Zhao Y, Yu Y, Sun J, Chai R. Recent advances in the application of MXenes for neural tissue engineering and regeneration. Neural Regeneration Research. 19: 258-263. PMID 37488875 DOI: 10.4103/1673-5374.379037 |
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He Z, Zhang S, Song Q, Li W, Liu D, Li H, Tang M, Chai R. The structural development of primary cultured hippocampal neurons on a graphene substrate. Colloids and Surfaces. B, Biointerfaces. 146: 442-451. PMID 27395037 DOI: 10.1016/J.Colsurfb.2016.06.045 |
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Wei H, Chen Z, Hu Y, Cao W, Ma X, Zhang C, Gao X, Qian X, Zhao Y, Chai R. Topographically Conductive Butterfly Wing Substrates for Directed Spiral Ganglion Neuron Growth. Small (Weinheim An Der Bergstrasse, Germany). e2102062. PMID 34411420 DOI: 10.1002/smll.202102062 |
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Shi L, Hong G, Chen C, Li X, Zhang H, Chai R, Sun D. Growth of spiral ganglion neurons induced by graphene oxide/oxidized bacterial cellulose composite hydrogel. Carbohydrate Polymers. 311: 120749. PMID 37028876 DOI: 10.1016/j.carbpol.2023.120749 |
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2015 |
Chao X, Fan Z, Han Y, Wang Y, Li J, Chai R, Xu L, Wang H. Effects of local application of methylprednisolone delivered by the C/GP-hydrogel on the recovery of facial nerves. Acta Oto-Laryngologica. 1-7. PMID 26235110 DOI: 10.3109/00016489.2015.1044563 |
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2022 |
Jiang P, Ma X, Han S, Ma L, Ai J, Wu L, Zhang Y, Xiao H, Tian M, Tao WA, Zhang S, Chai R. Characterization of the microRNA transcriptomes and proteomics of cochlear tissue-derived small extracellular vesicles from mice of different ages after birth. Cellular and Molecular Life Sciences : Cmls. 79: 154. PMID 35218422 DOI: 10.1007/s00018-022-04164-x |
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Liu W, Xu L, Wang X, Zhang D, Sun G, Wang M, Wang M, Han Y, Chai R, Wang H. PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage. Autophagy. PMID 33749526 DOI: 10.1080/15548627.2021.1905466 |
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Liao M, Hu Y, Zhang Y, Wang K, Fang Q, Qi Y, Shen Y, Cheng H, Fu X, Tang M, Sun S, Gao X, Chai R. 3D TiCT MXene-Matrigel with Electroacoustic Stimulation to Promote the Growth of Spiral Ganglion Neurons. Acs Nano. 16: 16744-16756. PMID 36222600 DOI: 10.1021/acsnano.2c06306 |
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2019 |
Xia L, Zhu W, Wang Y, He S, Chai R. Regulation of Neural Stem Cell Proliferation and Differentiation by Graphene-Based Biomaterials. Neural Plasticity. 2019: 3608386. PMID 31737061 DOI: 10.1155/2019/3608386 |
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2023 |
Wu Y, Zhang J, Liu Q, Miao Z, Chai R, Chen W. Development of Chinese herbal medicine for sensorineural hearing loss. Acta Pharmaceutica Sinica. B. 14: 455-467. PMID 38322328 DOI: 10.1016/j.apsb.2023.11.001 |
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2023 |
Yang W, Zhao X, Chai R, Fan J. Progress on mechanisms of age-related hearing loss. Frontiers in Neuroscience. 17: 1253574. PMID 37727326 DOI: 10.3389/fnins.2023.1253574 |
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2023 |
Guan Y, Du HB, Yang Z, Wang YZ, Ren R, Liu WW, Zhang C, Zhang JH, An WT, Li NN, Zeng XX, Li J, Sun YX, Wang YF, Yang F, ... ... Chai RJ, et al. Deafness-Associated ADGRV1 Mutation Impairs USH2A Stability through Improper Phosphorylation of WHRN and WDSUB1 Recruitment. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2205993. PMID 37066759 DOI: 10.1002/advs.202205993 |
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2021 |
Zhang Y, Li Y, Fu X, Wang P, Wang Q, Meng W, Wang T, Yang J, Chai R. The Detrimental and Beneficial Functions of Macrophages After Cochlear Injury. Frontiers in Cell and Developmental Biology. 9: 631904. PMID 34458249 DOI: 10.3389/fcell.2021.631904 |
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2022 |
Ma X, Guo J, Fu Y, Shen C, Jiang P, Zhang Y, Zhang L, Yu Y, Fan J, Chai R. G protein-coupled receptors in cochlea: Potential therapeutic targets for hearing loss. Frontiers in Molecular Neuroscience. 15: 1028125. PMID 36311029 DOI: 10.3389/fnmol.2022.1028125 |
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2020 |
Zhang F, Xia X, Chai R, Xu R, Xu Q, Liu M, Chen X, Liu B, Liu S, Liu N. Inhibition of USP14 suppresses the formation of foam cell by promoting CD36 degradation. Journal of Cellular and Molecular Medicine. PMID 31970862 DOI: 10.1111/jcmm.15002 |
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2021 |
Huang LJ, Mao XT, Li YY, Liu DD, Fan KQ, Liu RB, Wu TT, Wang HL, Zhang Y, Yang B, Ye CQ, Zhong JY, Chai RJ, Cao Q, Jin J. Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn's disease. Immunity. PMID 34343498 DOI: 10.1016/j.immuni.2021.07.004 |
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2023 |
Zhang H, Chen H, Lu L, Wang H, Zhao Y, Chai R. Natural Multifunctional Silk Microcarriers for Noise-Induced Hearing Loss Therapy. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2305215. PMID 37984871 DOI: 10.1002/advs.202305215 |
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2019 |
Xu R, Zhang F, Chai R, Zhou W, Hu M, Liu B, Chen X, Liu M, Xu Q, Liu N, Liu S. Exosomes derived from pro-inflammatory bone marrow-derived mesenchymal stem cells reduce inflammation and myocardial injury via mediating macrophage polarization. Journal of Cellular and Molecular Medicine. PMID 31557396 DOI: 10.1111/jcmm.14635 |
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2022 |
Qian F, Jiang X, Chai R, Liu D. The Roles of Solute Carriers in Auditory Function. Frontiers in Genetics. 13: 823049. PMID 35154281 DOI: 10.3389/fgene.2022.823049 |
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2022 |
Chai R, Li H, Yang T, Sun S, Yuan Y. Editorial: Hearing Loss: Mechanisms and Prevention. Frontiers in Cell and Developmental Biology. 10: 838271. PMID 35186939 DOI: 10.3389/fcell.2022.838271 |
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2018 |
Yang X, Zhou S, Wu J, Liao Q, Wang C, Liu M, Qu L, Zhang Y, Cheng C, Chai R, Zhang K, Yu X, Huang P, Liu L, Xiong W, et al. Surgery-free video-oculography in mouse models: enabling quantitative and short-interval longitudinal assessment of vestibular function. Neuroscience Letters. PMID 30597229 DOI: 10.1016/J.Neulet.2018.12.036 |
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Cai J, Zhang H, Hu Y, Huang Z, Wang Y, Xia Y, Chen X, Guo J, Cheng H, Xia L, Lu W, Zhang C, Xie J, Wang H, Chai R. GelMA-MXene hydrogel nerve conduits with microgrooves for spinal cord injury repair. Journal of Nanobiotechnology. 20: 460. PMID 36307790 DOI: 10.1186/s12951-022-01669-2 |
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2021 |
Yang Y, Gao B, Hu Y, Wei H, Zhang C, Chai R, Gu Z. Ordered inverse-opal scaffold based on bionic transpiration to create a biomimetic spine. Nanoscale. PMID 33929471 DOI: 10.1039/d1nr00731a |
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2022 |
Hu Y, Chen Z, Wang H, Guo J, Cai J, Chen X, Wei H, Qi J, Wang Q, Liu H, Zhao Y, Chai R. Conductive Nerve Guidance Conduits Based on Butterfly Wings for Peripheral Nerve Repair. Acs Nano. PMID 35112853 DOI: 10.1021/acsnano.1c11627 |
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2019 |
Fan KQ, Li YY, Wang HL, Mao XT, Guo JX, Wang F, Huang LJ, Li YN, Ma XY, Gao ZJ, Chen W, Qian DD, Xue WJ, Cao Q, Zhang L, ... ... Chai RJ, et al. Stress-Induced Metabolic Disorder in Peripheral CD4 T Cells Leads to Anxiety-like Behavior. Cell. 179: 864-879.e19. PMID 31675497 DOI: 10.1016/J.Cell.2019.10.001 |
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Wang S, Mao H, Hou L, Hu Z, Wang Y, Qi T, Tao C, Yang Y, Zhang C, Li M, Liu H, Hu S, Chai R, Wang Y. Compact SchCas9 Recognizes the Simple NNGR PAM. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2104789. PMID 34874112 DOI: 10.1002/advs.202104789 |
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2024 |
Cui W, Guo M, Liu D, Xiao P, Yang C, Huang H, Liang C, Yang Y, Fu X, Zhang Y, Liu J, Shi S, Cong J, Han Z, Xu Y, ... ... Chai R, et al. Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition. Nature Cell Biology. PMID 38168770 DOI: 10.1038/s41556-023-01314-6 |
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Han S, Sun J, He S, Tang M, Chai R. The application of graphene-based biomaterials in biomedicine. American Journal of Translational Research. 11: 3246-3260. PMID 31312342 |
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2024 |
Qi J, Tan F, Zhang L, Lu L, Zhang S, Zhai Y, Lu Y, Qian X, Dong W, Zhou Y, Zhang Z, Yang X, Jiang L, Yu C, Liu J, ... ... Chai R, et al. AAV-Mediated Gene Therapy Restores Hearing in Patients with DFNB9 Deafness. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2306788. PMID 38189623 DOI: 10.1002/advs.202306788 |
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2021 |
Fu X, Wan P, Li P, Wang J, Guo S, Zhang Y, An Y, Ye C, Liu Z, Gao J, Yang J, Fan J, Chai R. Mechanism and Prevention of Ototoxicity Induced by Aminoglycosides. Frontiers in Cellular Neuroscience. 15: 692762. PMID 34211374 DOI: 10.3389/fncel.2021.692762 |
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He Z, Fang Q, Waqas M, Wu X, Cheng C, He L, Sun Y, Kong W, Chai R. Role of Autophagy in Auditory System Development and Survival Journal of Otorhinolaryngology, Hearing and Balance Medicine. 1: 7. DOI: 10.3390/OHBM1010007 |
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2023 |
Zhao J, Fu H, Yu J, Hong W, Tian X, Qi J, Sun S, Zhao C, Wu C, Xu Z, Cheng L, Chai R, Yan W, Wei X, Shao Z. Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine. Nature Communications. 14: 962. PMID 36810324 DOI: 10.1038/s41467-023-36673-z |
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2016 |
Liu N, Chai R, Liu B, Zhang Z, Zhang S, Zhang J, Liao Y, Cai J, Xia X, Li A, Liu J, Huang H, Liu S. Ubiquitin-specific protease 14 regulates cardiac hypertrophy progression by increasing GSK-3β phosphorylation. Biochemical and Biophysical Research Communications. PMID 27545607 DOI: 10.1016/j.bbrc.2016.08.100 |
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Lv J, Wang H, Cheng X, Chen Y, Wang D, Zhang L, Cao Q, Tang H, Hu S, Gao K, Xun M, Wang J, Wang Z, Zhu B, Cui C, ... ... Chai R, et al. AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial. Lancet (London, England). PMID 38280389 DOI: 10.1016/S0140-6736(23)02874-X |
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2022 |
Liu BQ, Liu RB, Li WP, Mao XT, Li YN, Huang T, Wang HL, Chen HT, Zhong JY, Yang B, Chai RJ, Cao Q, Jin J, Li YY. XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7. Embo Reports. e55387. PMID 36394357 DOI: 10.15252/embr.202255387 |
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2021 |
Lai C, Liu X, Yan Q, Lv H, Zhou L, Hu L, Cai Y, Wang G, Chen Y, Chai R, Liu Z, Xu Y, Huang W, Xiao F, Hu L, et al. Low Innate Immunity and Lagged Adaptive Immune Response in the Re-Tested Viral RNA Positivity of a COVID-19 Patient. Frontiers in Immunology. 12: 664619. PMID 34305895 DOI: 10.3389/fimmu.2021.664619 |
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2019 |
Fu X, Chai R. Regulation of autophagy Journal of Bio-X Research. 2: 57-61. DOI: 10.1097/JBR.0000000000000031 |
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2021 |
Zhao C, Chen G, Wang H, Zhao Y, Chai R. Bio-inspired intestinal scavenger from microfluidic electrospray for detoxifying lipopolysaccharide. Bioactive Materials. 6: 1653-1662. PMID 33313445 DOI: 10.1016/j.bioactmat.2020.11.017 |
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2022 |
Xu Q, Liu M, Gu J, Ling S, Liu X, Luo Z, Jin Y, Chai R, Ou W, Liu S, Liu N. Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1. Cell Death Discovery. 8: 291. PMID 35710902 DOI: 10.1038/s41420-022-01086-2 |
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2020 |
Han S, Xu Y, Sun J, Liu Y, Zhao Y, Tao W, Chai R. Isolation and analysis of extracellular vesicles in a Morpho butterfly wing-integrated microvortex biochip. Biosensors & Bioelectronics. 154: 112073. PMID 32056968 DOI: 10.1016/j.bios.2020.112073 |
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2022 |
Guo L, Dai W, Xu Z, Liang Q, Miller ET, Li S, Gao X, Baldwin MW, Chai R, Li Q. Evolution of brain-expressed biogenic amine receptors into olfactory trace amine-associated receptors. Molecular Biology and Evolution. PMID 35021231 DOI: 10.1093/molbev/msac006 |
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2023 |
Cheng L, Sun S, Wang H, Zhao C, Tian X, Liu Y, Fu P, Shao Z, Chai R, Yan W. Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2. Signal Transduction and Targeted Therapy. 8: 364. PMID 37743365 DOI: 10.1038/s41392-023-01625-y |
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Wang S, Tao C, Mao H, Hou L, Wang Y, Qi T, Yang Y, Ong SG, Hu S, Chai R, Wang Y. Identification of SaCas9 orthologs containing a conserved serine residue that determines simple NNGG PAM recognition. Plos Biology. 20: e3001897. PMID 36449487 DOI: 10.1371/journal.pbio.3001897 |
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2021 |
Hu Y, Li D, Wei H, Zhou S, Chen W, Yan X, Cai J, Chen X, Chen B, Liao M, Chai R, Tang M. Neurite Extension and Orientation of Spiral Ganglion Neurons Can Be Directed by Superparamagnetic Iron Oxide Nanoparticles in a Magnetic Field. International Journal of Nanomedicine. 16: 4515-4526. PMID 34239302 DOI: 10.2147/IJN.S313673 |
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2021 |
Cai L, Zhao C, Chen H, Fan L, Zhao Y, Qian X, Chai R. Suction-Cup-Inspired Adhesive Micromotors for Drug Delivery. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2103384. PMID 34726356 DOI: 10.1002/advs.202103384 |
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2020 |
Zhang F, Xu R, Chai R, Xu Q, Liu M, Chen X, Chen X, Kong T, Zhang C, Liu SM, Zhang Z, Liu N. Deubiquitinase Inhibitor b-AP15 Attenuated LPS-Induced Inflammation via Inhibiting ERK1/2, JNK, and NF-Kappa B. Frontiers in Molecular Biosciences. 7: 49. PMID 32391376 DOI: 10.3389/fmolb.2020.00049 |
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2021 |
Qu C, Mao C, Xiao P, Shen Q, Zhong YN, Yang F, Shen DD, Tao X, Zhang H, Yan X, Zhao RJ, He J, Guan Y, Zhang C, Hou G, ... ... Chai RJ, et al. Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E receptor EP2 subtype. Science Advances. 7. PMID 33811074 DOI: 10.1126/sciadv.abf1268 |
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2018 |
Hu M, Zhang Z, Liu B, Zhang S, Chai R, Chen X, Kong T, Zhang F, Zhang J, Liu S, Liu N. Deubiquitinase Inhibitor Auranofin Attenuated Cardiac Hypertrophy by Blocking NF-κB Activation. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 45: 2421-2430. PMID 29554646 DOI: 10.1159/000488230 |
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2017 |
Xiong Y, Wang L, Mo P, Huang G, Li A, Chai R, Lin X, Zhong Y, Liu B, Ou W, Liu B, Liu SM. Association between HLA-DQB1 alleles and susceptibility to coronary artery disease in Southern Han Chinese. Human Immunology. PMID 28624488 DOI: 10.1016/j.humimm.2017.06.003 |
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2022 |
Zhao C, Chen G, Wang H, Zhao Y, Chai R. Corrigendum to "Bio-inspired intestinal scavenger from microfluidic electrospray for detoxifying lipopolysaccharide" [Bioact. Mater. 6 (2020) 1653-1662]. Bioactive Materials. 16: 12-14. PMID 35386325 DOI: 10.1016/j.bioactmat.2022.03.002 |
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2013 |
Chai R, Zhang J. Synergistic effect of hindered amine light stabilizers/ultraviolet absorbers on the polyvinyl chloride/powder nitrile rubber blends during photodegradation Polymer Engineering & Science. 53: 1760-1769. DOI: 10.1002/PEN.23432 |
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2011 |
ZHANG B, LIAO HT, JIN LJ, YAN H, DONG TM, WU HD, YU HM, CHAI RJ. [Retrograde percutaneous recanalization of chronic total occlusion of the coronary arteries via epicardial coronary collateral artery in 5 patients]. Zhonghua Xin Xue Guan Bing Za Zhi. 38: 794-7. PMID 21092646 |
0.01 |
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