Defu Zeng - Publications

Affiliations: 
Graduate School of Biological Sciences City of Hope's Irell & Manella Graduate School of Biomedical Sciences 
Area:
Physiology Biology, Molecular Biology, Cell Biology

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Li Q, Wang X, Song Q, Yang S, Wu X, Yang D, Marié IJ, Qin H, Zheng M, Nasri U, Kong X, Wang B, Lizhar E, Cassady K, Tompkins J, ... ... Zeng D, et al. Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity. The Journal of Clinical Investigation. 133. PMID 37526084 DOI: 10.1172/JCI165723  0.451
2023 Huang Y, Wu X, Tang S, Wu H, Nasri U, Qin Q, Song Q, Wang B, Tao H, Chong A, Riggs AD, Zeng D. Donor PD-L1 is required for organ transplant tolerance in MHC-mismatched mixed chimeras while PD-L1 and MHCII are not required for inducing chimerism. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 37105316 DOI: 10.1016/j.ajt.2023.04.022  0.439
2023 Zhang Y, Song Q, Cassady K, Lee M, Tang H, Zheng M, Wang B, Schones DE, Fu YX, Riggs AD, Martin PJ, Feng R, Zeng D. Blockade of trans PD-L1 interaction with CD80 augments antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2205085120. PMID 37036990 DOI: 10.1073/pnas.2205085120  0.338
2022 Zhao X, Yang W, Yu T, Yu Y, Cui X, Zhou Z, Yang H, Yu Y, Bilotta AJ, Yao S, Xu J, Zhou J, Yochum GS, Koltun WA, Portolese A, ... Zeng D, et al. Th17 cell-derived amphiregulin promotes colitis-associated intestinal fibrosis through activation of mTOR and MEK in intestinal myofibroblasts. Gastroenterology. PMID 36113570 DOI: 10.1053/j.gastro.2022.09.006  0.334
2022 Kong X, Wu X, Wang B, Zeng D, Cassady K, Nasri U, Zheng M, Wu A, Qin H, Tsai W, Salhotra A, Nakamura R, Martin PJ, Zeng D. Trafficking between clonally related peripheral T helper cells and tissue-resident T helper cells in chronic GVHD. Blood. PMID 36084473 DOI: 10.1182/blood.2022016581  0.47
2022 Song Q, Nasri U, Nakamura R, Martin PJ, Zeng D. Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity. Frontiers in Immunology. 13: 907673. PMID 35677056 DOI: 10.3389/fimmu.2022.907673  0.48
2021 Oh E, McCown EM, Ahn M, Garcia PA, Branciamore S, Tang S, Zeng DF, Roep BO, Thurmond DC. Syntaxin 4 enrichment in β-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice. Diabetes. PMID 34556496 DOI: 10.2337/db21-0170  0.31
2021 Song Q, Kong X, Martin PJ, Zeng D. Murine Models Provide New Insights Into Pathogenesis of Chronic Graft--Host Disease in Humans. Frontiers in Immunology. 12: 700857. PMID 34539630 DOI: 10.3389/fimmu.2021.700857  0.41
2021 Song Q, Wang X, Wu X, Kang TH, Qin H, Zhao D, Jenq RR, van den Brink MRM, Riggs AD, Martin PJ, Chen YZ, Zeng D. IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice. Nature Communications. 12: 805. PMID 33547295 DOI: 10.1038/s41467-021-21133-3  0.48
2021 Song Q, Wang X, Wu X, Qin H, Li Y, Riggs AD, Martin PJ, Chen Y, Zeng D. Tolerogenic anti-IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity. Blood. PMID 33511398 DOI: 10.1182/blood.2020006345  0.385
2020 Kong X, Zeng D, Wu X, Wang B, Yang S, Song Q, Zhu Y, Salas M, Qin H, Nasri U, Haas KM, Riggs AD, Nakamura R, Martin PJ, Huang A, ... Zeng D, et al. Tissue-resident PSGL1loCD4+ T cells promote B cell differentiation and chronic graft-versus-host-disease-associated autoimmunity. The Journal of Clinical Investigation. PMID 32931481 DOI: 10.1172/Jci135468  0.484
2020 Liu Y, Wang X, Zhu Y, Zhang M, Nasri U, Sun SS, Forman SJ, Riggs AD, Xi Z, Zeng D. Haploidentical mixed chimerism cures autoimmunity in established type 1 diabetic mice. The Journal of Clinical Investigation. PMID 32817590 DOI: 10.1172/JCI131799  0.474
2020 Tang S, Zhang M, Santamaria P, Riggs AD, Jin L, Zeng D. 260-OR: Transdifferentiation of a-Cells and Redifferentiation of InsulinLo ß-Cells Dominate ß-Cell Regeneration in Late-Stage Diabetic NOD Mice Cured with Induction of Mixed Chimerism and Administration of Gastrin and Epidermal Growth Factor Diabetes. 69. DOI: 10.2337/Db20-260-Or  0.403
2019 Zeng S, Song Q, Tang S, Wang X, Wang Y, Zeng D, Yang L. Combination Therapy of Allogeneic HSCT and In Vivo Activated iNKT Cells Prevents Acute Gvhd While Augmenting GVL Effect Blood. 134: 4439-4439. DOI: 10.1182/Blood-2019-130826  0.406
2019 Zhang C, Gao L, Liu Y, Gao L, Kong P, Liu J, Huang R, Ma Y, Zeng D, Xiong Q, Mei W, Liu J, Jiang P, Ye X, Han D, et al. Role of Donor-Derived CD19.CAR-T Cells in Treating Patients That Relapsed after Allogeneic Hematopoietic Stem Cell Transplantation Blood. 134: 4561-4561. DOI: 10.1182/Blood-2019-128262  0.607
2019 Wang X, Yang S, Wang Y, Wu X, Salas M, Song Q, Qin H, Nasri U, Riggs AD, Martin PJ, Zhang X, Zeng D. Stat3 -/- Alloreactive Donor T Cells Reduce FAO but Increase Leakage of ROS in Response to PD-1 Signaling Triggered By Host-Tissue PD-L1, Leading to Prevention of Gvhd While Preserving GVL Effect Blood. 134: 198-198. DOI: 10.1182/Blood-2019-127228  0.41
2019 Kong X, Zeng D, Wu X, Yang S, Wang B, Song Q, Zhu Y, Salas M, Qin H, Nasri U, Nakamura R, Martin PJ, Huang A, Zeng D. Tissue-Resident PSGL1loCD4+ T Cells Interact with B Cells Via PD-1 and PD-L2 in Gvhd Target Tissues to Augment Autoimmune-like Chronic Gvhd Blood. 134: 5607-5607. DOI: 10.1182/Blood-2019-126315  0.416
2019 Song Q, Wang X, Martin PJ, Chen Y, Zeng D. Expansion of Th/Tc17 T Cells and Loss of CX3CR1 + Macrophages Play a Critical Role in the Pathogenesis of Steroid-Refractory Acute Intestinal Gvhd Blood. 134: 1925-1925. DOI: 10.1182/Blood-2019-126261  0.431
2018 Cassady K, Martin PJ, Zeng D. Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80. Frontiers in Immunology. 9: 3061. PMID 30622541 DOI: 10.3389/Fimmu.2018.03061  0.463
2018 Zhang M, Racine JJ, Lin Q, Liu Y, Tang S, Qin Q, Qi T, Riggs AD, Zeng D. MHC-mismatched mixed chimerism restores peripheral tolerance of noncross-reactive autoreactive T cells in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463744 DOI: 10.1073/pnas.1720169115  0.804
2018 Zeng D. Newly found arsons ignite the fire of gut GVHD. The Journal of Clinical Investigation. PMID 29376890 DOI: 10.1172/JCI98685  0.398
2018 Song Q, Wang X, Martin PJ, Chen Y, Zeng D. Neutralizing IL-2 Early after HCT Specifically Prevents Expansion of Donor GM-CSF-Producing CD4+ T Cells That Initiate Acute Gut Gvhd Blood. 132: 2030-2030. DOI: 10.1182/Blood-2018-99-119966  0.558
2018 Yang S, Wang X, Zhang Y, Zeng D, Song Q, Martin PJ, Zhang X, Zeng D. Stat3 Regulates Alloreactive T Cell Susceptibility Towards PD-L1-Mediated Tolerance Signaling, Gvhd and GVL Activity Blood. 132: 3323-3323. DOI: 10.1182/Blood-2018-99-119474  0.629
2018 Gao S, Liu J, Peiyan K, Gao L, Zhang C, Liu Y, Yan H, Zhu L, Zeng D, Gao L, Zhang X. Decitabine Combined with FB3 As Conditional Regimen for Elderly Acute Myeloid Leukemia Patient with Allogeneic Hematopoietic Stem Cell Transplantation Blood. 132: 2108-2108. DOI: 10.1182/Blood-2018-99-115926  0.43
2018 Liu Y, Rao J, Li J, Wen Q, Lou S, Su Y, Yang T, Wang S, Lei G, Zhang C, Peiyan K, Gao L, Mai-Hong W, Zhu L, Xiang X, ... ... Zeng D, et al. Tandem Autologous Hematopoietic Stem Cell Transplantation Treatment for Adult T-Cell Lymphoblastic Lymphoma: A Multiple Center Prospective Study in Southwestern China Blood. 132: 5747-5747. DOI: 10.1182/Blood-2018-99-115705  0.422
2018 Guo-Fa X, Ting C, Huanfeng L, Shijia L, Gao L, Zhang C, Liu Y, Zhang X, Zeng D, Peiyan K. Efficacy of Low-Dose Decitabine in the Early Relapse of AML/MDS after Allogeneic Hematopoietic Stem Cell Transplantation Blood. 132: 5739-5739. DOI: 10.1182/Blood-2018-99-115659  0.361
2018 Liu J, Tan X, Ying-Ying M, Mai-Hong W, Liu Y, Lei G, Peiyan K, Zhang C, Zhang X, Zeng D. Study on Use of CAR-T Cells in Allogeneic Hematopoietic Stem Cell Transplantation Blood. 132: 5225-5225. DOI: 10.1182/Blood-2018-99-114287  0.584
2018 Cosgun KN, Hecht A, Yang X, Mangolini M, Aghajanirefah A, Xiao G, Sadras T, Chen Z, Klemm L, Geng H, Hong C, Song Q, Zeng D, Jumaa H, Zeng D, et al. Abstract 4515: Lgr5 mediates positive B-cell selection and is critical for initiation and survival of B-cell malignancies Cancer Research. 78: 4515-4515. DOI: 10.1158/1538-7445.Am2018-4515  0.337
2018 Song Q, Wu X, Zeng D, Xu S, Jenq RR, Brink MRMvd, Riggs AD, Chen Y, Zeng D. Tc17 Cells Mediate Gut Gvhd via IL-22 and Dysbiosis Biology of Blood and Marrow Transplantation. 24. DOI: 10.1016/J.Bbmt.2017.12.619  0.345
2017 Deng R, Hurtz C, Song Q, Yue C, Xiao G, Yu H, Wu X, Muschen M, Forman S, Martin PJ, Zeng D. Extrafollicular CD4(+) T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease. Nature Communications. 8: 978. PMID 29042531 DOI: 10.1038/S41467-017-00880-2  0.533
2017 Zeng D. Bridge between type 1 diabetes in mouse and man. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973949 DOI: 10.1073/Pnas.1715058114  0.486
2017 Ni X, Song Q, Cassady K, Deng R, Jin H, Zhang M, Dong H, Forman S, Martin PJ, Chen YZ, Wang J, Zeng D. PD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells. The Journal of Clinical Investigation. PMID 28414296 DOI: 10.1172/Jci91138  0.583
2016 Jin H, Ni X, Deng R, Song Q, Young J, Cassady K, Zhang M, Forman S, Martin PJ, Liu Q, Zeng D. Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice. Blood. PMID 26884373 DOI: 10.1182/Blood-2015-09-668145  0.575
2016 Zhang M, Lin Q, Qi T, Wang T, Chen CC, Riggs AD, Zeng D. Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26733677 DOI: 10.1073/Pnas.1524200113  0.387
2016 Zeng D, Strober S. Mechanisms of Tolerance Thomas' Hematopoietic Cell Transplantation: Fifth Edition. 1: 136-149. DOI: 10.1002/9781118416426.ch12  0.363
2015 Wu L, Li N, Zhang M, Xue SL, Cassady K, Lin Q, Riggs AD, Zeng D. MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26647186 DOI: 10.1073/Pnas.1521157112  0.611
2015 Deng R, Cassady K, Li X, Yao S, Zhang M, Racine J, Lin J, Chen L, Zeng D. B7H1/CD80 interaction augments PD-1-dependent T cell apoptosis and ameliorates graft-versus-host disease. Journal of Immunology (Baltimore, Md. : 1950). 194: 560-74. PMID 25488990 DOI: 10.4049/Jimmunol.1402157  0.778
2015 Racine JJ, Zhang M, Wang M, Morales W, Shen C, Zeng D. MHC-mismatched mixed chimerism mediates thymic deletion of cross-reactive autoreactive T cells and prevents insulitis in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 194: 407-17. PMID 25429069 DOI: 10.4049/Jimmunol.1401584  0.787
2015 Cassady KM, Zhou J, Riggs A, Zeng D. PD-L1/CD80 and PD-L1/PD-1 Signaling Reciprocally Regulate Alloreactive CD8+ T Cell Glycolysis, Proliferation, Apoptosis and Gvhd-Inducing Capacity Blood. 126: 4282-4282. DOI: 10.1182/Blood.V126.23.4282.4282  0.532
2015 Ni X, Song Q, Deng R, Jin H, Cassady KM, Zhang M, Forman SJ, Martin PJ, Wang J, Zeng D. Host Tissue PD-L1 Separates GVL Effect from Gvhd after Temporary Depletion of Donor CD4+ T Cells Early after HCT Blood. 126: 1882-1882. DOI: 10.1182/Blood.V126.23.1882.1882  0.638
2015 Deng R, Hurtz C, Yue C, Xiao G, Yu H, Muschen M, Forman SJ, Martin PJ, Zeng D. Extrafollicular CD4+ T and B Interaction Induces Chronic Gvhd in the Absence of Germinal Center Formation Blood. 126: 1875-1875. DOI: 10.1182/Blood.V126.23.1875.1875  0.554
2014 Wang M, Racine J, Zhang M, Wu T, Deng R, Johnston H, Shen C, Siswanto K, Zeng D. MHC-mismatched chimerism is required for induction of transplantation tolerance in autoimmune nonobese diabetic recipients. Journal of Immunology (Baltimore, Md. : 1950). 193: 2005-15. PMID 25000982 DOI: 10.4049/Jimmunol.1401137  0.804
2014 Johnston HF, Xu Y, Racine JJ, Cassady K, Ni X, Wu T, Chan A, Forman S, Zeng D. Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effects. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 1089-103. PMID 24796279 DOI: 10.1016/J.Bbmt.2014.04.028  0.815
2014 Zeng D. Regulators help new immigrants settle down? Blood. 123: 2754-6. PMID 24786456 DOI: 10.1182/blood-2014-03-562173  0.408
2014 He W, Racine JJ, Johnston HF, Li X, Li N, Cassady K, Liu C, Deng R, Martin P, Forman S, Zeng D. Depletion of host CCR7(+) dendritic cells prevented donor T cell tissue tropism in anti-CD3-conditioned recipients. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 920-8. PMID 24691220 DOI: 10.1016/J.Bbmt.2014.03.029  0.801
2014 Racine JJ, Wang M, Zhang M, Zeng D. Induction of mixed chimerism depletes pre-existing and de novo-developed autoreactive B cells in autoimmune NOD mice. Diabetes. 63: 2051-62. PMID 24458357 DOI: 10.2337/Db13-1532  0.811
2014 Li N, Lou J, Racine J, Forman SJ, Zeng D. Host Natural Killer T Cells Regulate Allogeneic Donor CD8+ T Cell Expression of Homing and Chemokine Receptors and Tissue Migration Blood. 124: 5804-5804. DOI: 10.1182/Blood.V124.21.5804.5804  0.814
2014 Xu Y, Johnston HF, Forman SJ, Zeng D. Oral Administration of Ibrutinib Is Ineffective at Preventing Scleroderma in Chronic Gvhd in Two Preclinical Mouse Models Blood. 124: 3818-3818. DOI: 10.1182/Blood.V124.21.3818.3818  0.639
2014 Jin H, Ni X, Deng R, Young J, Johnston HF, Liu Q, Zeng D. Antibodies from Donor B Cells Are Not Required for Initiating but Required for Persisting Scleroderma in Chronic Gvhd Blood. 124: 3817-3817. DOI: 10.1182/Blood.V124.21.3817.3817  0.686
2014 Deng R, Cassady K, Li X, Yao S, Zhang M, Racine J, Lin J, Chen L, Zeng D. B7H1/B7.1 Interaction Alleviate Acute Gvhd in a PD-1 Dependent Manner Blood. 124: 2423-2423. DOI: 10.1182/Blood.V124.21.2423.2423  0.774
2013 Wu T, Young JS, Johnston H, Ni X, Deng R, Racine J, Wang M, Wang A, Todorov I, Wang J, Zeng D. Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 488-99. PMID 23709681 DOI: 10.4049/Jimmunol.1300657  0.826
2013 Johnston HF, Xu Y, Ni X, Wu T, Racine J, Chan AC, Forman SJ, Zeng D. Administration Of Anti-CD20 Mab Is Highly Effective In Preventing But Ineffective In Treating Chronic GVHD While Preserving A Strong GVL Effect Blood. 122: 2010-2010. DOI: 10.1182/Blood.V122.21.2010.2010  0.812
2012 Young JS, Wu T, Chen Y, Zhao D, Liu H, Yi T, Johnston H, Racine J, Li X, Wang A, Todorov I, Zeng D. Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease. Journal of Immunology (Baltimore, Md. : 1950). 189: 222-33. PMID 22649197 DOI: 10.4049/Jimmunol.1200677  0.831
2012 Wang M, Racine JJ, Song X, Li X, Nair I, Liu H, Avakian-Mansoorian A, Johnston HF, Liu C, Shen C, Atkinson M, Todorov I, Kandeel F, Forman S, Wilson B, ... Zeng D, et al. Mixed chimerism and growth factors augment β cell regeneration and reverse late-stage type 1 diabetes. Science Translational Medicine. 4: 133ra59. PMID 22572882 DOI: 10.1126/Scitranslmed.3003835  0.761
2012 Li X, Deng R, He W, Liu C, Wang M, Young J, Meng Z, Du C, Huang W, Chen L, Chen Y, Martin P, Forman S, Zeng D. Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease. Journal of Immunology (Baltimore, Md. : 1950). 188: 724-34. PMID 22156590 DOI: 10.4049/Jimmunol.1102630  0.632
2011 Racine J, Wang M, Zhang C, Lin CL, Liu H, Todorov I, Atkinson M, Zeng D. Induction of mixed chimerism with MHC-mismatched but not matched bone marrow transplants results in thymic deletion of host-type autoreactive T-cells in NOD mice. Diabetes. 60: 555-64. PMID 21270266 DOI: 10.2337/Db10-0827  0.791
2011 Yi T, Li X, Yao S, Wang L, Chen Y, Zhao D, Johnston HF, Young JS, Liu H, Todorov I, Forman SJ, Chen L, Zeng D. Host APCs augment in vivo expansion of donor natural regulatory T cells via B7H1/B7.1 in allogeneic recipients. Journal of Immunology (Baltimore, Md. : 1950). 186: 2739-49. PMID 21263067 DOI: 10.4049/Jimmunol.1002939  0.61
2011 Zhao D, Young JS, Chen YH, Shen E, Yi T, Todorov I, Chu PG, Forman SJ, Zeng D. Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease. Journal of Immunology (Baltimore, Md. : 1950). 186: 856-68. PMID 21149609 DOI: 10.4049/Jimmunol.1002195  0.675
2011 Racine J, Zeng D. Induction of Mixed Chimerism for Reversal of Autoimmunity in Type 1 Diabetes Journal of Clinical & Cellular Immunology. 2013: 1-10. DOI: 10.4172/2155-9899.S2-006  0.781
2011 Liu C, He W, Li X, Johnston HF, Wang M, Racine J, Martin PJ, Forman S, Zeng D. Pretreatment with Anti-CD3 Monoclonal Antibody Depletes Recipient CCR7+ Dendritic Cells and Prevents Graft-Versus-Host Disease While Preserving GVL Effects, Blood. 118: 4024-4024. DOI: 10.1182/Blood.V118.21.4024.4024  0.809
2011 Young JS, Wu T, Chen Y, Zhao D, Johnston HF, Li X, Forman SJ, Zeng D. Donor B Cells in Transplants Augment Clonal Expansion and Persistence of Pathogenic Donor CD4+ T Cells in Autoimmune-Like Chronic Graft-Versus-Host Disease, Blood. 118: 4021-4021. DOI: 10.1182/Blood.V118.21.4021.4021  0.668
2011 Li X, He W, Deng R, Liu C, Wang M, Young J, Chen L, Chen Y, Martin PJ, Forman S, Zeng D. Tissue Parenchymal Cell Expression of B7-H1 Inhibits Infiltrating T Cell Expansion and Prevents Persistence of Graft-Versus-Host Disease Blood. 118: 2974-2974. DOI: 10.1182/Blood.V118.21.2974.2974  0.614
2010 Zhang C, Wang M, Racine JJ, Liu H, Lin CL, Nair I, Lau J, Cao YA, Todorov I, Atkinson M, Zeng D. Induction of chimerism permits low-dose islet grafts in the liver or pancreas to reverse refractory autoimmune diabetes. Diabetes. 59: 2228-36. PMID 20530743 DOI: 10.2337/Db10-0450  0.722
2009 Yi T, Chen Y, Wang L, Du G, Huang D, Zhao D, Johnston H, Young J, Todorov I, Umetsu DT, Chen L, Iwakura Y, Kandeel F, Forman S, Zeng D. Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood. 114: 3101-12. PMID 19602708 DOI: 10.1182/Blood-2009-05-219402  0.517
2009 Li N, Chen Y, He W, Yi T, Zhao D, Zhang C, Lin CL, Todorov I, Kandeel F, Forman S, Zeng D. Anti-CD3 preconditioning separates GVL from GVHD via modulating host dendritic cell and donor T-cell migration in recipients conditioned with TBI. Blood. 113: 953-62. PMID 18922852 DOI: 10.1182/Blood-2008-06-165522  0.631
2009 He W, Kirschbaum M, Li N, Yi T, Liu H, Forman S, Zeng D. Synergistic Effect of Anti-CD3 and Vorinostat in the Prevention of Acute Gvhd and Retention of GVL in a Radiation-Free Conditioning Regimen. Blood. 114: 3562-3562. DOI: 10.1182/Blood.V114.22.3562.3562  0.628
2009 Zhao D, Chen Y, Young J, Shen E, Yi T, Liu H, Chu PG, Zeng D. Donor CD4+ T Cells That Possess Both Allo- and Autoreactivity in Transplants Mediate Chronic Graft Versus Host Disease. Blood. 114: 3555-3555. DOI: 10.1182/Blood.V114.22.3555.3555  0.67
2009 Young JS, Zhao D, Yi T, Liu H, Zeng D. Mutual Activation and Expansion of Donor CD4 + T Cells and B Cells in Transplants Play a Critical Role in the Initiation of Chronic Graft-Versus-Host Disease. Blood. 114: 1342-1342. DOI: 10.1182/Blood.V114.22.1342.1342  0.675
2009 Zeng D, Zhao D, Nakamura R. Response: Is CD103 a good surface marker for in vivo–activated effector/memory Treg cells in patients with chronic inflammation? Unknown yet Blood. 113: 2120-2120. DOI: 10.1182/Blood-2008-12-190405  0.595
2008 Yi T, Zhao D, Lin CL, Zhang C, Chen Y, Todorov I, LeBon T, Kandeel F, Forman S, Zeng D. Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease. Blood. 112: 2101-10. PMID 18596226 DOI: 10.1182/Blood-2007-12-126987  0.485
2008 Zhao D, Zhang C, Yi T, Lin CL, Todorov I, Kandeel F, Forman S, Zeng D. In vivo-activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease. Blood. 112: 2129-38. PMID 18550852 DOI: 10.1182/Blood-2008-02-140277  0.638
2008 Li N, Zhao D, Kirschbaum M, Zhang C, Lin CL, Todorov I, Kandeel F, Forman S, Zeng D. HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen. Proceedings of the National Academy of Sciences of the United States of America. 105: 4796-801. PMID 18347343 DOI: 10.1073/Pnas.0712051105  0.623
2008 Chen Y, Lin C, Li N, Du G, Chen L, Forman S, Zeng D. Radiation-Free Anti-CD3-Conditioning Regimen Maintains Tissue Protection Mechanisms and Prevents GVHD: Role of Tissue Expression of B7H1 Blood. 112: 62-62. DOI: 10.1182/Blood.V112.11.62.62  0.57
2008 Li N, Chen Y, He W, Yi T, Zhao D, Zhang C, Lin C, Forman S, Zeng D. Anti-CD3 preconditioning separates GVL from GVHD via modulating host dendritic and donor T cell migration in TBI-conditioned recipients Blood. 112: 4611-4611. DOI: 10.1182/Blood.V112.11.4611.4611  0.615
2007 Zhang C, Todorov I, Lin CL, Atkinson M, Kandeel F, Forman S, Zeng D. Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 2337-42. PMID 17267595 DOI: 10.1073/Pnas.0611101104  0.543
2007 Zhang C, Lou J, Li N, Todorov I, Lin CL, Cao YA, Contag CH, Kandeel F, Forman S, Zeng D. Donor CD8+ T cells mediate graft-versus-leukemia activity without clinical signs of graft-versus-host disease in recipients conditioned with anti-CD3 monoclonal antibody Journal of Immunology. 178: 838-850. PMID 17202345 DOI: 10.4049/Jimmunol.178.2.838  0.655
2007 Li N, Zhao D, Zhang C, Lin C, Kirschbaum M, Kandeel F, Forman S, Zeng D. Histone Deacetylase Inhibitor SAHA Reduces Cytokine Storm and Facilitates Induction of Chimerism When Combined with Anti-CD3 mAb in Conditioning of Recipients. Blood. 110: 2168-2168. DOI: 10.1182/Blood.V110.11.2168.2168  0.623
2007 Zhang C, Kandeel F, Todorov I, Atkinson M, Lin C, Forman S, Zeng D. Elimination of Insulitis and Augmentation of Islet β Cell Regeneration via Induction of Chimerism in Overtly Diabetic NOD Mice Clinical Immunology. 123. DOI: 10.1016/J.Clim.2007.03.474  0.382
2006 Zhang C, Todorov I, Zhang Z, Liu Y, Kandeel F, Forman S, Strober S, Zeng D. Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations. Blood. 107: 2993-3001. PMID 16352808 DOI: 10.1182/Blood-2005-09-3623  0.644
2006 Li N, Zhang C, Lin C, McCulloch B, Wright J, Kirschbaum M, Forman S, Zeng D. A Radiation-Free Immune and Epigenetics Based Conditioning Regimen for Allogeneic HCT: Combination of Anti-CD3 and Romidepsin. Blood. 108: 3204-3204. DOI: 10.1182/Blood.V108.11.3204.3204  0.645
2006 Zhang C, Lou J, Li N, Todorov I, Lin C, Cao Y, Contag CH, Kandeel F, Forman S, Zeng D. Donor CD8 + T Cells Mediate GVL without GVHD in Recipients Conditioned with Anti-CD3 mAb. Blood. 108: 192-192. DOI: 10.1182/Blood.V108.11.192.192  0.658
2006 Zhang C, Lou J, Todorov I, Li N, Lin C, Cao Y, Contag C, Kandeel F, Forman S, Zeng D. OR.85. Donor CD8+ T-Cells Mediate GVL without GVHD in Recipients Conditioned with Anti-CD3 mAB Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.390  0.594
2005 Liang Y, Huang T, Zhang C, Todorov I, Atkinson M, Kandeel F, Forman S, Zeng D. Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in autoimmune NOD mice conditioned with anti-CD3 mAb. Blood. 105: 2180-8. PMID 15374883 DOI: 10.1182/Blood-2004-06-2411  0.66
2005 Zhang C, Todorov I, Zhang Z, Liu Y, Kandeel F, Forman S, Strober S, Zeng D. Donor CD4+ T and B Cells in Transplants Induce Autoimmune-Like Chronic Graft Versus Host Disease. Blood. 106: 1313-1313. DOI: 10.1182/Blood.V106.11.1313.1313  0.631
2004 Hueber W, Zeng D, Strober S, Utz PJ. Interferon-alpha-inducible proteins are novel autoantigens in murine lupus. Arthritis and Rheumatism. 50: 3239-49. PMID 15476221 DOI: 10.1002/Art.20508  0.543
2004 Hueber W, Zeng D, Sharpe O, Robinson WH, Strober S, Utz PJ. Characterization of novel antigens recognized by serum autoantibodies from anti-CD1 TCR-transgenic lupus mice. European Journal of Immunology. 34: 1654-62. PMID 15162435 DOI: 10.1002/Eji.200324201  0.5
2004 Zeng D, Lan F, Hoffmann P, Strober S. Suppression of graft-versus-host disease by naturally occurring regulatory T cells. Transplantation. 77: S9-S11. PMID 14726761 DOI: 10.1097/01.Tp.0000106475.38978.11  0.549
2003 Zeng D, Liu Y, Sidobre S, Kronenberg M, Strober S. Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus. The Journal of Clinical Investigation. 112: 1211-22. PMID 14561706 DOI: 10.1172/Jci17165  0.537
2003 Lan F, Zeng D, Higuchi M, Higgins JP, Strober S. Host conditioning with total lymphoid irradiation and antithymocyte globulin prevents graft-versus-host disease: the role of CD1-reactive natural killer T cells. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 9: 355-63. PMID 12813443 DOI: 10.1016/S1083-8791(03)00108-3  0.649
2002 Higuchi M, Zeng D, Shizuru J, Gworek J, Dejbakhsh-Jones S, Taniguchi M, Strober S. Immune tolerance to combined organ and bone marrow transplants after fractionated lymphoid irradiation involves regulatory NK T cells and clonal deletion. Journal of Immunology (Baltimore, Md. : 1950). 169: 5564-70. PMID 12421933 DOI: 10.4049/Jimmunol.169.10.5564  0.624
2002 Zeng D, Hoffmann P, Lan F, Huie P, Higgins J, Strober S. Unique patterns of surface receptors, cytokine secretion, and immune functions distinguish T cells in the bone marrow from those in the periphery: impact on allogeneic bone marrow transplantation. Blood. 99: 1449-57. PMID 11830499 DOI: 10.1182/Blood.V99.4.1449  0.626
2001 Lan F, Zeng D, Higuchi M, Huie P, Higgins JP, Strober S. Predominance of NK1.1+TCR alpha beta+ or DX5+TCR alpha beta+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: "natural suppressor" cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 2087-96. PMID 11489992 DOI: 10.4049/Jimmunol.167.4.2087  0.58
2001 Dejbakhsh-Jones S, Garcia-Ojeda ME, Chatterjea-Matthes D, Zeng D, Strober S. Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway. Proceedings of the National Academy of Sciences of the United States of America. 98: 7455-60. PMID 11390986 DOI: 10.1073/Pnas.131559798  0.529
2001 Lan F, Zeng D, Huie P, Higgins JP, Strober S. Allogeneic bone marrow cells that facilitate complete chimerism and eliminate tumor cells express both CD8 and T-cell antigen receptor-alphabeta. Blood. 97: 3458-65. PMID 11369637 DOI: 10.1182/Blood.V97.11.3458  0.616
2000 Zeng D, Lee MK, Tung J, Brendolan A, Strober S. Cutting edge: A role for CD1 in the pathogenesis of lupus in NZB/NZW mice Journal of Immunology. 164: 5000-5004. PMID 10799851 DOI: 10.4049/Jimmunol.164.10.5000  0.543
2000 Chen Y, Zeng D, Schlegel PG, Fidler J, Chao NJ. PG27, an extract of Tripterygium wilfordii hook f, induces antigen-specific tolerance in bone marrow transplantation in mice Blood. 95: 705-710. DOI: 10.1182/BLOOD.V95.2.705  0.362
1999 Hayamizu K, Zeng D, Strober S. Donor cells that facilitate tolerance to rat heart allografts after posttransplant total lymphoid irradiation and rabbit anti-thymocyte globulin. Transplantation Proceedings. 31: 25S-26S. PMID 10330965 DOI: 10.1016/S0041-1345(99)00099-8  0.426
1999 Zeng D, Lewis D, Dejbakhsh-Jones S, Lan F, García-Ojeda M, Sibley R, Strober S. Bone marrow NK1.1(-) and NK1.1(+) T cells reciprocally regulate acute graft versus host disease. The Journal of Experimental Medicine. 189: 1073-81. PMID 10190898 DOI: 10.1084/Jem.189.7.1073  0.624
1998 Hayamizu K, Zeng D, Huie P, Garcia-Ojeda ME, Bloch DA, Fong L, Engleman EG, Sibley RK, Strober S. Donor blood monocytes but not T or B cells facilitate long-term allograft survival after total lymphoid irradiation. Transplantation. 66: 585-93. PMID 9753336 DOI: 10.1097/00007890-199809150-00006  0.449
1998 Zeng D, Dick M, Cheng L, Amano M, Dejbakhsh-Jones S, Huie P, Sibley R, Strober S. Subsets of transgenic T cells that recognize CD1 induce or prevent murine lupus: role of cytokines. The Journal of Experimental Medicine. 187: 525-36. PMID 9463403 DOI: 10.1084/Jem.187.4.525  0.614
1997 Zeng D, Dejbakhsh-Jones S, Strober S. Granulocyte Colony-Stimulating Factor Reduces the Capacity of Blood Mononuclear Cells to Induce Graft-Versus-Host Disease: Impact on Blood Progenitor Cell Transplantation Blood. 90: 453-463. DOI: 10.1182/Blood.V90.1.453.453_453_463  0.586
1997 Zeng D, Dejbakhsh-Jones S, Strober S. Granulocyte Colony-Stimulating Factor Reduces the Capacity of Blood Mononuclear Cells to Induce Graft-Versus-Host Disease: Impact on Blood Progenitor Cell Transplantation Blood. 90: 453-463. DOI: 10.1182/blood.v90.1.453  0.509
1996 Strober S, Cheng L, Zeng D, Palathumpat R, Dejbakhsh-Jones S, Huie P, Sibley R. Double negative (CD4-CD8- alpha beta+) T cells which promote tolerance induction and regulate autoimmunity. Immunological Reviews. 149: 217-30. PMID 9005216 DOI: 10.1111/J.1600-065X.1996.Tb00906.X  0.484
1996 Zeng D, Ready A, Huie P, Hayamizu K, Holm B, Yin D, Sibley RK, Strober S. Mechanisms of tolerance to rat heart allografts using posttransplant TLI: Changes in cytokine expression Transplantation. 62: 510-517. PMID 8781618 DOI: 10.1097/00007890-199608270-00014  0.372
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