| Year |
Citation |
Score |
| 2024 |
Alissa N, Fang WB, Medrano M, Bergeron N, Kozai Y, Hu Q, Redding C, Thyfault J, Reeves JH, Berkland C, Cheng N. C-C chemokine ligand 2 signaling promotes skeletal muscle wasting in non-tumor and breast tumor mouse models. Disease Models & Mechanisms. PMID 38973385 DOI: 10.1242/dmm.050398 |
0.501 |
|
| 2023 |
Fang WB, Medrano M, Cote P, Portsche M, Rao V, Hong Y, Behbod F, Knapp JR, Bloomer C, Noel-Macdonnell J, Cheng N. Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive breast cancer. Frontiers in Oncology. 13: 1130911. PMID 37091166 DOI: 10.3389/fonc.2023.1130911 |
0.391 |
|
| 2022 |
Acevedo DS, Fang WB, Rao V, Penmetcha V, Leyva H, Acosta G, Cote P, Brodine R, Swerdlow R, Tan L, Lorenzi PL, Cheng N. Regulation of growth, invasion and metabolism of breast ductal carcinoma through CCL2/CCR2 signaling interactions with MET receptor tyrosine kinases. Neoplasia (New York, N.Y.). 28: 100791. PMID 35405500 DOI: 10.1016/j.neo.2022.100791 |
0.52 |
|
| 2021 |
Fang WB, Sofia Acevedo D, Smart C, Zinda B, Alissa N, Warren K, Fraga G, Huang LC, Shyr Y, Li W, Xie L, Staggs V, Hong Y, Behbod F, Cheng N. Expression of CCL2/CCR2 signaling proteins in breast carcinoma cells is associated with invasive progression. Scientific Reports. 11: 8708. PMID 33888841 DOI: 10.1038/s41598-021-88229-0 |
0.543 |
|
| 2019 |
Brummer G, Fang W, Smart C, Zinda B, Alissa N, Berkland C, Miller D, Cheng N. CCR2 signaling in breast carcinoma cells promotes tumor growth and invasion by promoting CCL2 and suppressing CD154 effects on the angiogenic and immune microenvironments. Oncogene. PMID 31827233 DOI: 10.1038/S41388-019-1141-7 |
0.561 |
|
| 2019 |
Hu Q, Myers M, Fang W, Yao M, Brummer G, Hawj J, Smart C, Berkland C, Cheng N. Role of ALDH1A1 and HTRA2 expression to CCL2/CCR2 mediated breast cancer cell growth and invasion. Biology Open. PMID 31208996 DOI: 10.1242/Bio.040873 |
0.614 |
|
| 2018 |
Yao M, Fang W, Smart C, Hu Q, Huang S, Alvarez N, Fields P, Cheng N. CCR2 chemokine receptors enhance growth and cell cycle progression of breast cancer cells through SRC and PKC activation. Molecular Cancer Research : McR. PMID 30446625 DOI: 10.1158/1541-7786.Mcr-18-0750 |
0.607 |
|
| 2018 |
Vishwakarma V, New J, Kumar D, Snyder V, Arnold L, Nissen E, Hu Q, Cheng N, Miller D, Thomas AR, Shnayder Y, Kakarala K, Tsue TT, Girod DA, Thomas SM. Potent Antitumor Effects of a Combination of Three Nutraceutical Compounds. Scientific Reports. 8: 12163. PMID 30111862 DOI: 10.1038/S41598-018-29683-1 |
0.386 |
|
| 2018 |
Bernard S, Myers M, Fang WB, Zinda B, Smart C, Lambert D, Zou A, Fan F, Cheng N. CXCL1 Derived from Mammary Fibroblasts Promotes Progression of Mammary Lesions to Invasive Carcinoma through CXCR2 Dependent Mechanisms. Journal of Mammary Gland Biology and Neoplasia. PMID 30094610 DOI: 10.1007/S10911-018-9407-1 |
0.741 |
|
| 2017 |
Brummer G, Acevedo DS, Hu Q, Portsche M, Fang W, Yao M, Zinda B, Myers M, Alvarez NS, Fields P, Hong Y, Behbod F, Cheng N. Chemokine Signaling Facilitates Early-stage Breast Cancer Survival and Invasion through Fibroblast-dependent Mechanisms. Molecular Cancer Research : McR. PMID 29133591 DOI: 10.1158/1541-7786.Mcr-17-0308 |
0.623 |
|
| 2017 |
Yao M, Smart C, Hu Q, Cheng N. Continuous Delivery of Neutralizing Antibodies Elevate CCL2 Levels in Mice Bearing MCF10CA1d Breast Tumor Xenografts. Translational Oncology. 10: 734-743. PMID 28734227 DOI: 10.1016/J.Tranon.2017.06.009 |
0.503 |
|
| 2017 |
Yao M, Fang WB, Fan F, Alvarez N, Fields PE, Cheng N. Abstract 2984: The chemokine CCL2/CCR2 signaling mediated fibroblasts-cancer cells crosstalk promotes basal like breast cancer progression Cancer Research. 77: 2984-2984. DOI: 10.1158/1538-7445.Am2017-2984 |
0.594 |
|
| 2016 |
Oien DB, Chien J, Cheng N. Regulation of chemo-sensitivity in ovarian cancer via a stroma dependent glutathione pathway. Translational Cancer Research. 5: S514-S519. PMID 30542639 DOI: 10.21037/Tcr.2016.09.32 |
0.46 |
|
| 2016 |
Yao M, Brummer G, Acevedo D, Cheng N. Cytokine Regulation of Metastasis and Tumorigenicity. Advances in Cancer Research. 132: 265-367. PMID 27613135 DOI: 10.1016/Bs.Acr.2016.05.005 |
0.506 |
|
| 2016 |
Fang WB, Yao M, Brummer G, Acevedo D, Alhakamy N, Berkland C, Cheng N. Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment. Oncotarget. PMID 27283985 DOI: 10.18632/Oncotarget.9885 |
0.552 |
|
| 2016 |
Yao M, Yu E, Staggs V, Fan F, Cheng N. Elevated expression of chemokine C-C ligand 2 in stroma is associated with recurrent basal-like breast cancers. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27125354 DOI: 10.1038/Modpathol.2016.78 |
0.611 |
|
| 2016 |
Jolly LA, Novitskiy SV, Owens P, Massoll N, Cheng N, Fang W, Moses HL, Franco AT. Fibroblast-mediated collagen remodeling within the tumor microenvironment facilitates progression of thyroid cancers driven by BrafV600E and Pten loss. Cancer Research. PMID 26818109 DOI: 10.1158/0008-5472.Can-15-2351 |
0.464 |
|
| 2016 |
Yao M, Yu E, Staggs V, Fan F, Cheng N. Elevated expression of chemokine C-C ligand 2 in stroma is associated with recurrent basal-like breast cancers Modern Pathology. DOI: 10.1038/modpathol.2016.78 |
0.546 |
|
| 2015 |
Fang WB, Mafuvadze B, Yao M, Zou A, Portsche M, Cheng N. TGF-β Negatively Regulates CXCL1 Chemokine Expression in Mammary Fibroblasts through Enhancement of Smad2/3 and Suppression of HGF/c-Met Signaling Mechanisms. Plos One. 10: e0135063. PMID 26252654 DOI: 10.1371/Journal.Pone.0135063 |
0.748 |
|
| 2015 |
Fang WB, Yao M, Jokar I, Alhakamy N, Berkland C, Chen J, Brantley-Sieders D, Cheng N. The CCL2 chemokine is a negative regulator of autophagy and necrosis in luminal B breast cancer cells. Breast Cancer Research and Treatment. 150: 309-20. PMID 25744294 DOI: 10.1007/S10549-015-3324-4 |
0.597 |
|
| 2015 |
Mafuvadze B, Fang WB, Cheng N. Abstract P4-05-02: Overexpression of the chemokine receptor CCR2 in the breast epithelium is associated with progression of DCIS Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P4-05-02 |
0.614 |
|
| 2015 |
Zou A, Lambert D, Yeh H, Fang WB, Cheng N. Abstract A62: TGF-β regulates CXCL1 expression in mammary carcinoma associated fibroblasts through novel Smad2/3- and HGF/c-Met-dependent mechanisms. Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-A62 |
0.754 |
|
| 2014 |
Zou A, Lambert D, Yeh H, Yasukawa K, Behbod F, Fan F, Cheng N. Elevated CXCL1 expression in breast cancer stroma predicts poor prognosis and is inversely associated with expression of TGF-β signaling proteins. Bmc Cancer. 14: 781. PMID 25344051 DOI: 10.1186/1471-2407-14-781 |
0.754 |
|
| 2014 |
Fang WB, Yao M, Cheng N. Priming cancer cells for drug resistance: role of the fibroblast niche. Frontiers in Biology. 9: 114-126. PMID 25045348 DOI: 10.1007/S11515-014-1300-8 |
0.442 |
|
| 2013 |
Fang WB, Alhakamy N, Berkland C, Cheng N. Abstract A063: Targeting the CCL2 chemokine pathway in breast tumors through intratumoral delivery of calcium cross linked TAT peptide: siRNA complexes Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A063 |
0.557 |
|
| 2012 |
Fang WB, Jokar I, Zou A, Lambert D, Dendukuri P, Cheng N. CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 protein- and p42/44 mitogen-activated protein kinase (MAPK)-dependent mechanisms. The Journal of Biological Chemistry. 287: 36593-608. PMID 22927430 DOI: 10.1074/Jbc.M112.365999 |
0.745 |
|
| 2012 |
Fang WB, Berkland C, Cheng N. Abstract 1952: Targeting the CCL2/CCR2 chemokine pathway in breast tumors through intratumoral delivery of calcium cross linked TAT peptide: siRNA complexes Cancer Research. 72: 1952-1952. DOI: 10.1158/1538-7445.Am2012-1952 |
0.575 |
|
| 2011 |
Cheng N, Lambert DL. Mammary transplantation of stromal cells and carcinoma cells in C57BL/6J mice. Journal of Visualized Experiments : Jove. PMID 21860377 DOI: 10.3791/2716 |
0.361 |
|
| 2011 |
Fang WB, Jokar I, Chytil A, Moses HL, Abel T, Cheng N. Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression. Clinical & Experimental Metastasis. 28: 351-66. PMID 21374085 DOI: 10.1007/S10585-011-9373-0 |
0.58 |
|
| 2010 |
Hembruff SL, Jokar I, Yang L, Cheng N. Loss of transforming growth factor-beta signaling in mammary fibroblasts enhances CCL2 secretion to promote mammary tumor progression through macrophage-dependent and -independent mechanisms. Neoplasia (New York, N.Y.). 12: 425-33. PMID 20454514 DOI: 10.1593/Neo.10200 |
0.586 |
|
| 2010 |
Xu BJ, Yan W, Jovanovic B, An AQ, Cheng N, Aakre ME, Yi Y, Eng J, Link AJ, Moses HL. Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts. Proteomics. 10: 2458-70. PMID 20405477 DOI: 10.1002/Pmic.200900701 |
0.528 |
|
| 2009 |
Hembruff SL, Cheng N. Chemokine signaling in cancer: Implications on the tumor microenvironment and therapeutic targeting. Cancer Therapy. 7: 254-267. PMID 20651940 |
0.42 |
|
| 2009 |
Bierie B, Chung CH, Parker JS, Stover DG, Cheng N, Chytil A, Aakre M, Shyr Y, Moses HL. Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer. The Journal of Clinical Investigation. 119: 1571-82. PMID 19451693 DOI: 10.1172/Jci37480 |
0.57 |
|
| 2008 |
Cheng N, Chytil A, Shyr Y, Joly A, Moses HL. Transforming growth factor-beta signaling-deficient fibroblasts enhance hepatocyte growth factor signaling in mammary carcinoma cells to promote scattering and invasion. Molecular Cancer Research : McR. 6: 1521-33. PMID 18922968 DOI: 10.1158/1541-7786.Mcr-07-2203 |
0.533 |
|
| 2008 |
Brown KA, Ham AJ, Clark CN, Meller N, Law BK, Chytil A, Cheng N, Pietenpol JA, Moses HL. Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1. Journal of Cellular Biochemistry. 105: 596-611. PMID 18729074 DOI: 10.1002/Jcb.21860 |
0.431 |
|
| 2007 |
Bonine-Summers AR, Aakre ME, Brown KA, Arteaga CL, Pietenpol JA, Moses HL, Cheng N. Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells. Cancer Biology & Therapy. 6: 561-70. PMID 17495520 DOI: 10.4161/Cbt.6.4.3851 |
0.474 |
|
| 2007 |
Cheng N, Chytil A, Shyr Y, Joly A, Moses HL. Enhanced hepatocyte growth factor signaling by type II transforming growth factor-beta receptor knockout fibroblasts promotes mammary tumorigenesis. Cancer Research. 67: 4869-77. PMID 17495323 DOI: 10.1158/0008-5472.Can-06-3381 |
0.508 |
|
| 2005 |
Xie L, Xu BJ, Gorska AE, Shyr Y, Schwartz SA, Cheng N, Levy S, Bierie B, Caprioli RM, Moses HL. Genomic and proteomic analysis of mammary tumors arising in transgenic mice. Journal of Proteome Research. 4: 2088-98. PMID 16335954 DOI: 10.1021/Pr050214L |
0.468 |
|
| 2005 |
Cheng N, Bhowmick NA, Chytil A, Gorksa AE, Brown KA, Muraoka R, Arteaga CL, Neilson EG, Hayward SW, Moses HL. Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks. Oncogene. 24: 5053-68. PMID 15856015 DOI: 10.1038/Sj.Onc.1208685 |
0.526 |
|
| 2005 |
Moses H, Cheng N, Chytil A, Gorska A, Aakre M, Forrester E, Neilson E, Bhowmick N. Stromal and epithelial TGF-β signaling in mammary tumorigenesis Breast Cancer Research. 7. DOI: 10.1186/Bcr1045 |
0.487 |
|
| 2003 |
Cheng N, Brantley D, Fang WB, Liu H, Fanslow W, Cerretti DP, Bussell KN, Reith A, Jackson D, Chen J. Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors. Neoplasia (New York, N.Y.). 5: 445-56. PMID 14670182 DOI: 10.1016/S1476-5586(03)80047-7 |
0.434 |
|
| 2002 |
Brantley DM, Cheng N, Thompson EJ, Lin Q, Brekken RA, Thorpe PE, Muraoka RS, Cerretti DP, Pozzi A, Jackson D, Lin C, Chen J. Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo. Oncogene. 21: 7011-26. PMID 12370823 DOI: 10.1038/Sj.Onc.1205679 |
0.42 |
|
| 2002 |
Cheng N, Brantley DM, Chen J. The ephrins and Eph receptors in angiogenesis. Cytokine & Growth Factor Reviews. 13: 75-85. PMID 11750881 DOI: 10.1016/S1359-6101(01)00031-4 |
0.407 |
|
| 2001 |
Cheng N, Chen J. Tumor Necrosis Factor-α Induction of Endothelial Ephrin A1 Expression Is Mediated by a p38 MAPK- and SAPK/JNK-dependent but Nuclear Factor-κB-independent Mechanism Journal of Biological Chemistry. 276: 13771-13777. PMID 11278471 DOI: 10.1074/Jbc.M009147200 |
0.365 |
|
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