Bradley E. Bernstein - Related publications

Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Genetics, Molecular Biology, Bioinformatics Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Cusack M, King HW, Spingardi P, Kessler BM, Klose RJ, Kriaucionis S. Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors. Genome Research. 30: 1393-1406. PMID 32963030 DOI: 10.1101/gr.257576.119   
2020 Papin C, Le Gras S, Ibrahim A, Salem H, Karimi MM, Stoll I, Ugrinova I, Schröder M, Fontaine-Pelletier E, Omran Z, Bronner C, Dimitrov S, Hamiche A. CpG Islands Shape the Epigenome Landscape. Journal of Molecular Biology. PMID 33010306 DOI: 10.1016/j.jmb.2020.09.018   
2020 Zaret KS. Pioneer Transcription Factors Initiating Gene Network Changes. Annual Review of Genetics. PMID 32886547 DOI: 10.1146/annurev-genet-030220-015007   
2020 Kurup JT, Han Z, Jin W, Kidder BL. H4K20me3 methyltransferase SUV420H2 shapes the chromatin landscape of pluripotent embryonic stem cells. Development (Cambridge, England). PMID 33144397 DOI: 10.1242/dev.188516   
2020 Lee YH, Kim MS, Jeong H, Hagiwara A, Lee JS. Genome-wide identification and transcriptional modulation of histone variants and modification related genes in the low pH-exposed marine rotifer Brachionus koreanus. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 36: 100748. PMID 33032078 DOI: 10.1016/j.cbd.2020.100748   
2020 Liu YX, Li QZ, Cao YN, Zhang LQ. Identification of key genes and important histone modifications in hepatocellular carcinoma. Computational and Structural Biotechnology Journal. 18: 2657-2669. PMID 33033585 DOI: 10.1016/j.csbj.2020.09.013   
2020 Zhang M, Zhao J, Lv Y, Wang W, Feng C, Zou W, Su L, Jiao J. Histone Variants and Histone Modifications in Neurogenesis. Trends in Cell Biology. PMID 33011018 DOI: 10.1016/j.tcb.2020.09.003   
2020 Yao Z, Chen Y, Cao W, Shyh-Chang N. Chromatin-modifying drugs and metabolites in cell fate control. Cell Proliferation. e12898. PMID 32979011 DOI: 10.1111/cpr.12898   
2020 Yan W, Guo Y, Xu F, Saxena D, Li X. Identification of Differentially Methylated Regions Associated with a Knockout of SUV39H1 in Prostate Cancer Cells. Genes. 11. PMID 33066102 DOI: 10.3390/genes11101188   
2020 Formosa T, Winston F. The role of FACT in managing chromatin: disruption, assembly, or repair? Nucleic Acids Research. PMID 33104782 DOI: 10.1093/nar/gkaa912   
2020 Perreault AA, Brown JD, Venters BJ. Erythropoietin Regulates Transcription and YY1 Dynamics in a Pre-established Chromatin Architecture. Iscience. 23: 101583. PMID 33089097 DOI: 10.1016/j.isci.2020.101583   
2020 Li G, Tian Y, Zhu WG. The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy. Frontiers in Cell and Developmental Biology. 8: 576946. PMID 33117804 DOI: 10.3389/fcell.2020.576946   
2020 Herrera-Uribe J, Liu H, Byrne KA, Bond ZF, Loving CL, Tuggle CK. Changes in H3K27ac at Gene Regulatory Regions in Porcine Alveolar Macrophages Following LPS or PolyIC Exposure. Frontiers in Genetics. 11: 817. PMID 32973863 DOI: 10.3389/fgene.2020.00817   
2020 Greenfield G, McPherson S, Smith J, Mead A, Harrison C, Mills K, McMullin MF. Modification of the Histone Landscape with JAK Inhibition in Myeloproliferative Neoplasms. Cancers. 12. PMID 32962027 DOI: 10.3390/cancers12092669   
2020 Li L, Li N, Liu N, Huo F, Zheng J. MBD2 Correlates with a Poor Prognosis and Tumor Progression in Renal Cell Carcinoma. Oncotargets and Therapy. 13: 10001-10012. PMID 33116585 DOI: 10.2147/OTT.S256226   
2020 Lutsik P, Baude A, Mancarella D, Öz S, Kühn A, Toth R, Hey J, Toprak UH, Lim J, Nguyen VH, Jiang C, Mayakonda A, Hartmann M, Rosemann F, Breuer K, et al. Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone. Nature Communications. 11: 5414. PMID 33110075 DOI: 10.1038/s41467-020-18955-y   
2020 Miron E, Oldenkamp R, Brown JM, Pinto DMS, Xu CS, Faria AR, Shaban HA, Rhodes JDP, Innocent C, de Ornellas S, Hess HF, Buckle V, Schermelleh L. Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin. Science Advances. 6. PMID 32967822 DOI: 10.1126/sciadv.aba8811   
2020 Miron E, Oldenkamp R, Brown JM, Pinto DMS, Xu CS, Faria AR, Shaban HA, Rhodes JDP, Innocent C, de Ornellas S, Hess HF, Buckle V, Schermelleh L. Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin. Science Advances. 6. PMID 32967822 DOI: 10.1126/sciadv.aba8811   
2020 Navarro C, Lyu J, Katsori AM, Caridha R, Elsässer SJ. An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility. Nature Communications. 11: 5095. PMID 33037201 DOI: 10.1038/s41467-020-18863-1   
2020 Guzman F, Fazeli Y, Khuu M, Salcido K, Singh S, Benavente CA. Retinoblastoma Tumor Suppressor Protein Roles in Epigenetic Regulation. Cancers. 12. PMID 33003565 DOI: 10.3390/cancers12102807   
2020 Abshiru NA, Sikora JW, Camarillo JM, Morris JA, Compton PD, Lee T, Neelamraju Y, Haddox S, Sheridan C, Carroll M, Cripe LD, Tallman MS, Paietta EM, Melnick AM, Thomas PM, et al. Targeted detection and quantitation of histone modifications from 1,000 cells. Plos One. 15: e0240829. PMID 33104722 DOI: 10.1371/journal.pone.0240829   
2020 Sato H, Singer RH, Greally JM. Quantitative Kinetic Analyses of Histone Turnover Using Imaging and Flow Cytometry. Bio-Protocol. 10. PMID 33043098 DOI: 10.21769/bioprotoc.3738   
2020 Chin HG, Sun Z, Vishnu US, Hao P, Cejas P, Spracklin G, Estève PO, Xu SY, Long HW, Pradhan S. Universal NicE-seq for high-resolution accessible chromatin profiling for formaldehyde-fixed and FFPE tissues. Clinical Epigenetics. 12: 143. PMID 32962734 DOI: 10.1186/s13148-020-00921-6   
2020 Valiulienė G, Vitkevičienė A, Navakauskienė R. The epigenetic treatment remodel genome-wide histone H4 hyper-acetylation patterns and affect signaling pathways in acute promyelocytic leukemia cells. European Journal of Pharmacology. 889: 173641. PMID 33045196 DOI: 10.1016/j.ejphar.2020.173641   
2020 Khadka J, Pesok A, Grafi G. Plant Histone HTB (H2B) Variants in Regulating Chromatin Structure and Function. Plants (Basel, Switzerland). 9. PMID 33113795 DOI: 10.3390/plants9111435   
2020 Jiang Q, Ang JYJ, Lee AY, Cao Q, Li KY, Yip KY, Leung DCY. G9a Plays Distinct Roles in Maintaining DNA Methylation, Retrotransposon Silencing, and Chromatin Looping. Cell Reports. 33: 108315. PMID 33113380 DOI: 10.1016/j.celrep.2020.108315   
2020 Akone SH, Ntie-Kang F, Stuhldreier F, Ewonkem MB, Noah AM, Mouelle SEM, Müller R. Natural Products Impacting DNA Methyltransferases and Histone Deacetylases. Frontiers in Pharmacology. 11: 992. PMID 32903500 DOI: 10.3389/fphar.2020.00992   
2020 Kumagai A, Dunphy WG. Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication. Cell Reports. 32: 108178. PMID 32966791 DOI: 10.1016/j.celrep.2020.108178   
2020 Bulathsinghalage C, Liu L. Network-based method for regions with statistically frequent interchromosomal interactions at single-cell resolution. Bmc Bioinformatics. 21: 369. PMID 32998686 DOI: 10.1186/s12859-020-03689-x   
2020 Eich ML, Athar M, Ferguson JE, Varambally S. EZH2-targeted therapies in cancer: hype or a reality. Cancer Research. PMID 32978169 DOI: 10.1158/0008-5472.CAN-20-2147   
2020 Kedhari Sundaram M, Haque S, Somvanshi P, Bhardwaj T, Hussain A. Epigallocatechin gallate inhibits HeLa cells by modulation of epigenetics and signaling pathways. 3 Biotech. 10: 484. PMID 33117625 DOI: 10.1007/s13205-020-02473-1   
2020 Jain SU, Khazaei S, Marchione DM, Lundgren SM, Wang X, Weinberg DN, Deshmukh S, Juretic N, Lu C, Allis CD, Garcia BA, Jabado N, Lewis PW. Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression. Proceedings of the National Academy of Sciences of the United States of America. PMID 33067396 DOI: 10.1073/pnas.2006076117   
2020 Neve B, Jonckheere N, Vincent A, Van Seuningen I. Long non-coding RNAs: the tentacles of chromatin remodeler complexes. Cellular and Molecular Life Sciences : Cmls. PMID 33001247 DOI: 10.1007/s00018-020-03646-0   
2020 Boila LD, Sengupta A. Evolving insights on histone methylome regulation in human acute myeloid leukemia pathogenesis and targeted therapy. Experimental Hematology. PMID 32950598 DOI: 10.1016/j.exphem.2020.09.189   
2020 Xie WJ, Qi Y, Zhang B. Characterizing chromatin folding coordinate and landscape with deep learning. Plos Computational Biology. 16: e1008262. PMID 32986691 DOI: 10.1371/journal.pcbi.1008262   
2020 Yi SJ, Kim K. New Insights into the Role of Histone Changes in Aging. International Journal of Molecular Sciences. 21. PMID 33153221 DOI: 10.3390/ijms21218241   
2020 Ambrosini S, Mohammed SA, Costantino S, Paneni F. Disentangling the epigenetic landscape in cardiovascular patients: a path toward personalized medicine. Minerva Cardioangiologica. PMID 32996305 DOI: 10.23736/S0026-4725.20.05326-8   
2020 Tian H, Yang Z, Xu X, Liu L. [Three-dimensional chromosome conformation capture and its derived technologies]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 36: 2040-2050. PMID 33169569 DOI: 10.13345/j.cjb.200112   
2020 Agarwal G, Kudapa H, Ramalingam A, Choudhary D, Sinha P, Garg V, Singh VK, Patil GB, Pandey MK, Nguyen HT, Guo B, Sunkar R, Niederhuth CE, Varshney RK. Epigenetics and epigenomics: underlying mechanisms, relevance, and implications in crop improvement. Functional & Integrative Genomics. PMID 33089419 DOI: 10.1007/s10142-020-00756-7   
2020 Francis NJ, Sihou D. Inheritance of Histone (H3/H4): A Binary Choice? Trends in Biochemical Sciences. PMID 32917507 DOI: 10.1016/j.tibs.2020.08.009   
2020 Yuan ZD, Zhu WN, Liu KZ, Huang ZP, Han YC. Small Molecule Epigenetic Modulators in Pure Chemical Cell Fate Conversion. Stem Cells International. 2020: 8890917. PMID 33144865 DOI: 10.1155/2020/8890917   
2020 Wang F, Bai X, Wang Y, Jiang Y, Ai B, Zhang Y, Liu Y, Xu M, Wang Q, Han X, Pan Q, Li Y, Li X, Zhang J, Zhao J, et al. ATACdb: a comprehensive human chromatin accessibility database. Nucleic Acids Research. PMID 33125076 DOI: 10.1093/nar/gkaa943   
2020 Moon Y, Kim I, Chang S, Park B, Lee S, Yoo S, Chae S, Hwang D, Park H. Hypoxia regulates allele-specific histone modification of the imprinted H19 gene. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194643. PMID 33035707 DOI: 10.1016/j.bbagrm.2020.194643   
2020 Murphy KE, Meng FW, Makowski CE, Murphy PJ. Genome-wide chromatin accessibility is restricted by ANP32E. Nature Communications. 11: 5063. PMID 33033242 DOI: 10.1038/s41467-020-18821-x   
2020 Li Z, Rasmussen LJ. TIP60 in Aging and Neurodegeneration. Ageing Research Reviews. 101195. PMID 33091598 DOI: 10.1016/j.arr.2020.101195   
2020 Mossanen-Parsi A, Parisi D, Browne-Marke N, Bharudin I, Connell SR, Mayans O, Fucini P, Morozov IY, Caddick MX. Histone mRNA is subject to 3´ uridylation and re-adenylation in Aspergillus nidulans. Molecular Microbiology. PMID 33047379 DOI: 10.1111/mmi.14613   
2020 Mossanen-Parsi A, Parisi D, Browne-Marke N, Bharudin I, Connell SR, Mayans O, Fucini P, Morozov IY, Caddick MX. Histone mRNA is subject to 3´ uridylation and re-adenylation in Aspergillus nidulans. Molecular Microbiology. PMID 33047379 DOI: 10.1111/mmi.14613   
2020 Haas J, Bloesel D, Bacher S, Kracht M, Schmitz ML. Chromatin Targeting of HIPK2 Leads to Acetylation-Dependent Chromatin Decondensation. Frontiers in Cell and Developmental Biology. 8: 852. PMID 32984337 DOI: 10.3389/fcell.2020.00852   
2020 Zhang Y, Jiang C, Trudeau SJ, Narita Y, Zhao B, Teng M, Guo R, Gewurz BE. Histone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation. Mbio. 11. PMID 33109754 DOI: 10.1128/mBio.01063-20   
2020 Lei B, Capella M, Montgomery SA, Borg M, Osakabe A, Goiser M, Muhammad A, Braun S, Berger F. A Synthetic Approach to Reconstruct the Evolutionary and Functional Innovations of the Plant Histone Variant H2A.W. Current Biology : Cb. PMID 33096036 DOI: 10.1016/j.cub.2020.09.080