Randall Allen Hughes - Publications

Affiliations: 
2008 Chemistry University of Texas at Austin, Austin, Texas, U.S.A. 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Shroff R, Ellefson JW, Wang SS, Boulgakov AA, Hughes RA, Ellington AD. Recovery of Information Stored in Modified DNA with an Evolved Polymerase. Acs Synthetic Biology. 11: 554-561. PMID 35113518 DOI: 10.1021/acssynbio.1c00575  0.709
2021 Goike J, Hsieh CL, Horton A, Gardner EC, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Renberg R, Johanson MJ, Cardona JA, Segall-Shapiro T, Zhou L, Nissly RH, ... ... Hughes RA, et al. Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality. Biorxiv : the Preprint Server For Biology. PMID 33851158 DOI: 10.1101/2021.04.07.438849  0.446
2020 Van Leuven JT, Ederer MM, Burleigh K, Scott L, Hughes RA, Codrea V, Ellington AD, Wichman H, Miller C. ΦX174 Attenuation by Whole Genome Codon Deoptimization. Genome Biology and Evolution. PMID 33045052 DOI: 10.1093/gbe/evaa214  0.395
2020 Lee J, Der BS, Karamitros CS, Li W, Marshall NM, Lungu OI, Miklos AE, Xu J, Kang TH, Lee CH, Tan B, Hughes RA, Jung ST, Ippolito GC, Gray JJ, et al. Computer-based Engineering of Thermostabilized Antibody Fragments. Aiche Journal. American Institute of Chemical Engineers. 66. PMID 32336757 DOI: 10.1002/Aic.16864  0.697
2020 Zamanian-Daryoush M, Gogonea V, DiDonato AJ, Buffa JA, Choucair I, Levison BS, Hughes RA, Ellington AD, Huang Y, Li XS, DiDonato JA, Hazen SL. Site-specific 5-hydroxy-tryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high density lipoprotein biogenesis. The Journal of Biological Chemistry. PMID 32098873 DOI: 10.1074/Jbc.Ra119.012092  0.371
2017 Entzminger KC, Hyun JM, Pantazes RJ, Patterson-Orazem AC, Qerqez AN, Frye ZP, Hughes RA, Ellington AD, Lieberman RL, Maranas CD, Maynard JA. De novo design of antibody complementarity determining regions binding a FLAG tetra-peptide. Scientific Reports. 7: 10295. PMID 28860479 DOI: 10.1038/S41598-017-10737-9  0.52
2017 Hughes RA, Ellington AD. Synthetic DNA Synthesis and Assembly: Putting the Synthetic in Synthetic Biology. Cold Spring Harbor Perspectives in Biology. 9. PMID 28049645 DOI: 10.1101/Cshperspect.A023812  0.526
2016 Singh-Blom A, Hughes RA, Ellington AD. Corrigendum to "An amino acid depleted cell-free protein synthesis system for the incorporation of non-canonical amino acid analogs into proteins" [J. Biotechnol. 178 (2014) 12-22]. Journal of Biotechnology. 231: 296. PMID 27470576 DOI: 10.1016/J.Jbiotec.2016.06.031  0.519
2015 Du Y, Hughes RA, Bhadra S, Jiang YS, Ellington AD, Li B. A Sweet Spot for Molecular Diagnostics: Coupling Isothermal Amplification and Strand Exchange Circuits to Glucometers. Scientific Reports. 5: 11039. PMID 26050646 DOI: 10.1038/Srep11039  0.652
2014 Singh-Blom A, Hughes RA, Ellington AD. An amino acid depleted cell-free protein synthesis system for the incorporation of non-canonical amino acid analogs into proteins. Journal of Biotechnology. 178: 12-22. PMID 24631721 DOI: 10.1016/J.Jbiotec.2014.02.009  0.538
2014 Ellefson JW, Meyer AJ, Hughes RA, Cannon JR, Brodbelt JS, Ellington AD. Directed evolution of genetic parts and circuits by compartmentalized partnered replication. Nature Biotechnology. 32: 97-101. PMID 24185096 DOI: 10.1038/Nbt.2714  0.718
2014 Xu J, Tack D, Hughes RA, Ellington AD, Gray JJ. Structure-based non-canonical amino acid design to covalently crosslink an antibody-antigen complex. Journal of Structural Biology. 185: 215-22. PMID 23680795 DOI: 10.1016/J.Jsb.2013.05.003  0.526
2013 Singh-Blom A, Hughes RA, Ellington AD. Residue-specific incorporation of unnatural amino acids into proteins in vitro and in vivo. Methods in Molecular Biology (Clifton, N.J.). 978: 93-114. PMID 23423891 DOI: 10.1007/978-1-62703-293-3_7  0.544
2013 Wine Y, Boutz DR, Lavinder JJ, Miklos AE, Hughes RA, Hoi KH, Jung ST, Horton AP, Murrin EM, Ellington AD, Marcotte EM, Georgiou G. Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response. Proceedings of the National Academy of Sciences of the United States of America. 110: 2993-8. PMID 23382245 DOI: 10.1073/Pnas.1213737110  0.494
2012 Hughes RA, Miklos AE, Ellington AD. Enrichment of error-free synthetic DNA sequences by CEL I nuclease. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit3.24. PMID 22870859 DOI: 10.1002/0471142727.Mb0324S99  0.535
2012 Miklos AE, Hughes RA, Ellington AD. Design and assembly of large synthetic DNA constructs. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit3.23. PMID 22870858 DOI: 10.1002/0471142727.Mb0323S99  0.516
2012 Romero PA, Stone E, Lamb C, Chantranupong L, Krause A, Miklos AE, Hughes RA, Fechtel B, Ellington AD, Arnold FH, Georgiou G. SCHEMA-designed variants of human Arginase I and II reveal sequence elements important to stability and catalysis. Acs Synthetic Biology. 1: 221-8. PMID 22737599 DOI: 10.1021/Sb300014T  0.476
2012 Miklos AE, Kluwe C, Der BS, Pai S, Sircar A, Hughes RA, Berrondo M, Xu J, Codrea V, Buckley PE, Calm AM, Welsh HS, Warner CR, Zacharko MA, Carney JP, et al. Structure-based design of supercharged, highly thermoresistant antibodies. Chemistry & Biology. 19: 449-55. PMID 22520751 DOI: 10.1016/J.Chembiol.2012.01.018  0.536
2011 Hughes RA, Miklos AE, Ellington AD. Gene synthesis: methods and applications. Methods in Enzymology. 498: 277-309. PMID 21601682 DOI: 10.1016/B978-0-12-385120-8.00012-7  0.529
2010 Reddy ST, Ge X, Miklos AE, Hughes RA, Kang SH, Hoi KH, Chrysostomou C, Hunicke-Smith SP, Iverson BL, Tucker PW, Ellington AD, Georgiou G. Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells. Nature Biotechnology. 28: 965-9. PMID 20802495 DOI: 10.1038/Nbt.1673  0.503
2010 Hughes RA, Ellington AD. Rational design of an orthogonal tryptophanyl nonsense suppressor tRNA. Nucleic Acids Research. 38: 6813-30. PMID 20571084 DOI: 10.1093/Nar/Gkq521  0.511
2005 Hughes RA, Ellington AD. Mistakes in translation don't translate into termination. Proceedings of the National Academy of Sciences of the United States of America. 102: 1273-4. PMID 15677335 DOI: 10.1073/Pnas.0409443101  0.515
2004 Bacher JM, Hughes RA, Tze-Fei Wong J, Ellington AD. Evolving new genetic codes. Trends in Ecology & Evolution. 19: 69-75. PMID 16701231 DOI: 10.1016/J.Tree.2003.11.007  0.508
2004 Hughes RA, Robertson MP, Ellington AD, Levy M. The importance of prebiotic chemistry in the RNA world. Current Opinion in Chemical Biology. 8: 629-33. PMID 15556407 DOI: 10.1016/J.Cbpa.2004.09.007  0.654
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