Nicolas L. Fawzi, Ph.D. - Publications

Affiliations: 
Molecular Pharmacology, Physiology and Biotechnology Brown University, Providence, RI 
Area:
Neurodegenerative diseases, NMR
Website:
https://research.brown.edu/research/profile.php?id=1346961432

43/96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tang WS, Fawzi NL, Mittal J. Refining All-Atom Protein Force Fields for Polar-Rich, Prion-like, Low-Complexity Intrinsically Disordered Proteins. The Journal of Physical Chemistry. B. PMID 33078950 DOI: 10.1021/acs.jpcb.0c07545  0.307
2020 Ryan VH, Watters S, Amaya J, Khatiwada B, Venditti V, Naik MT, Fawzi NL. Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation. Nucleic Acids Research. PMID 32870271 DOI: 10.1093/Nar/Gkaa710  0.332
2020 Fawzi NL. Elastin phase separation — structure or disorder? Nature Reviews Molecular Cell Biology. 21: 1-1. PMID 32860012 DOI: 10.1038/S41580-020-00291-0  0.33
2020 Conicella AE, Dignon GL, Zerze GH, Schmidt HB, D'Ordine AM, Kim YC, Rohatgi R, Ayala YM, Mittal J, Fawzi NL. TDP-43 α-helical structure tunes liquid-liquid phase separation and function. Proceedings of the National Academy of Sciences of the United States of America. PMID 32132204 DOI: 10.1073/Pnas.1912055117  0.37
2020 Murthy AC, Fawzi NL. The (un)structural biology of biomolecular liquid-liquid phase separation using NMR spectroscopy. The Journal of Biological Chemistry. PMID 31911439 DOI: 10.1074/Jbc.Rev119.009847  0.401
2020 Mathews KL, Marglous J, Fawzi NL. Structural and Biophysical Characterization of Splicing-Associated Assemblies of the SMN Protein Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1228  0.381
2019 Ryan VH, Fawzi NL. Physiological, Pathological, and Targetable Membraneless Organelles in Neurons. Trends in Neurosciences. PMID 31493925 DOI: 10.1016/J.Tins.2019.08.005  0.315
2019 Stackpole EE, Akins MR, Ivshina M, Murthy AC, Fawzi NL, Fallon JR. EGFP insertional mutagenesis reveals multiple FXR2P fibrillar states with differing ribosome association in neurons. Biology Open. 8. PMID 31434643 DOI: 10.1242/Bio.046383  0.315
2019 Murthy AC, Dignon GL, Kan Y, Zerze GH, Parekh SH, Mittal J, Fawzi NL. Molecular interactions underlying liquid-liquid phase separation of the FUS low-complexity domain. Nature Structural & Molecular Biology. 26: 637-648. PMID 31270472 DOI: 10.1038/S41594-019-0250-X  0.356
2019 Cable J, Brangwynne C, Seydoux G, Cowburn D, Pappu RV, Castañeda CA, Berchowitz LE, Chen Z, Jonikas M, Dernburg A, Mittag T, Fawzi NL. Phase separation in biology and disease-a symposium report. Annals of the New York Academy of Sciences. PMID 31199001 DOI: 10.1111/Nyas.14126  0.312
2018 Amaya J, Ryan VH, Fawzi NL. The SH3 domain of Fyn kinase interacts with and induces liquid-liquid phase separation of the low complexity domain of hnRNPA2. The Journal of Biological Chemistry. PMID 30397184 DOI: 10.1074/Jbc.Ra118.005120  0.317
2018 Yoshizawa T, Ali R, Jiou J, Fung HYJ, Burke KA, Kim SJ, Lin Y, Peeples WB, Saltzberg D, Soniat M, Baumhardt JM, Oldenbourg R, Sali A, Fawzi NL, Rosen MK, et al. Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell. 173: 693-705.e22. PMID 29677513 DOI: 10.1016/J.Cell.2018.03.003  0.314
2018 Boeynaems S, Alberti S, Fawzi NL, Mittag T, Polymenidou M, Rousseau F, Schymkowitz J, Shorter J, Wolozin B, Van Den Bosch L, Tompa P, Fuxreiter M. Protein Phase Separation: A New Phase in Cell Biology. Trends in Cell Biology. PMID 29602697 DOI: 10.1016/J.Tcb.2018.02.004  0.349
2018 Wang A, Conicella AE, Schmidt HB, Martin EW, Rhoads SN, Reeb AN, Nourse A, Ramirez Montero D, Ryan VH, Rohatgi R, Shewmaker F, Naik MT, Mittag T, Ayala YM, Fawzi NL. A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing. The Embo Journal. PMID 29438978 DOI: 10.15252/Embj.201797452  0.382
2018 Ryan VH, Dignon GL, Zerze GH, Chabata CV, Silva R, Conicella AE, Amaya J, Burke KA, Mittal J, Fawzi NL. Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation. Molecular Cell. PMID 29358076 DOI: 10.1016/J.Molcel.2017.12.022  0.343
2018 Venditti V, Fawzi NL. Probing the Atomic Structure of Transient Protein Contacts by Paramagnetic Relaxation Enhancement Solution NMR. Methods in Molecular Biology (Clifton, N.J.). 1688: 243-255. PMID 29151213 DOI: 10.1007/978-1-4939-7386-6_12  0.399
2017 Janke AM, Seo DH, Rahmanian V, Conicella AE, Mathews KL, Burke KA, Mittal J, Fawzi NL. Lysines in RNA polymerase II C-terminal domain contribute to TAF15 fibril recruitment. Biochemistry. PMID 28945358 DOI: 10.1021/Acs.Biochem.7B00310  0.313
2017 Monahan Z, Ryan VH, Janke AM, Burke KA, Rhoads SN, Zerze GH, O'Meally R, Dignon GL, Conicella AE, Zheng W, Best RB, Cole RN, Mittal J, Shewmaker F, Fawzi NL. Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity. The Embo Journal. PMID 28790177 DOI: 10.15252/Embj.201696394  0.383
2017 Fawzi N. Visualizing Structural Details of Disordered Domain Phase Separation Associated with ALS and Cancers Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.046  0.334
2016 Conicella AE, Zerze GH, Mittal J, Fawzi NL. ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain. Structure (London, England : 1993). PMID 27545621 DOI: 10.1016/J.Str.2016.07.007  0.372
2015 Burke KA, Janke AM, Rhine CL, Fawzi NL. Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II. Molecular Cell. PMID 26455390 DOI: 10.1016/J.Molcel.2015.09.006  0.405
2014 Fawzi NL, Libich DS, Ying J, Tugarinov V, Clore GM. Characterizing methyl-bearing side chain contacts and dynamics mediating amyloid β protofibril interactions using ¹³C(methyl)-DEST and lifetime line broadening. Angewandte Chemie (International Ed. in English). 53: 10345-9. PMID 25130489 DOI: 10.1002/Anie.201405180  0.375
2014 Conicella AE, Fawzi NL. The C-terminal threonine of Aβ43 nucleates toxic aggregation via structural and dynamical changes in monomers and protofibrils. Biochemistry. 53: 3095-105. PMID 24773532 DOI: 10.1021/Bi500131A  0.45
2013 Libich DS, Fawzi NL, Ying J, Clore GM. Probing the transient dark state of substrate binding to GroEL by relaxation-based solution NMR. Proceedings of the National Academy of Sciences of the United States of America. 110: 11361-6. PMID 23798407 DOI: 10.1073/Pnas.1305715110  0.411
2012 Fawzi NL, Ying J, Torchia DA, Clore GM. Probing exchange kinetics and atomic resolution dynamics in high-molecular-weight complexes using dark-state exchange saturation transfer NMR spectroscopy. Nature Protocols. 7: 1523-33. PMID 22814391 DOI: 10.1038/Nprot.2012.077  0.357
2012 Cellmer T, Fawzi NL. Coarse-grained simulations of protein aggregation. Methods in Molecular Biology (Clifton, N.J.). 899: 453-70. PMID 22735969 DOI: 10.1007/978-1-61779-921-1_27  0.402
2012 Venditti V, Fawzi NL, Clore GM. An efficient protocol for incorporation of an unnatural amino acid in perdeuterated recombinant proteins using glucose-based media. Journal of Biomolecular Nmr. 52: 191-5. PMID 22350951 DOI: 10.1007/S10858-012-9606-9  0.308
2012 Ball KA, Phillips AH, Fawzi NL, Wemmer DE, Head-Gordon T. Amyloid-Beta Heterogeneous Conformational Ensembles: Differences Between the 40- and 42-Residue Peptides and Implications for Dimer Polyamorphism Biophysical Journal. 102: 631a. DOI: 10.1016/J.Bpj.2011.11.3437  0.664
2011 Fawzi NL, Ying J, Ghirlando R, Torchia DA, Clore GM. Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR. Nature. 480: 268-72. PMID 22037310 DOI: 10.1038/Nature10577  0.424
2011 Venditti V, Fawzi NL, Clore GM. Automated sequence- and stereo-specific assignment of methyl-labeled proteins by paramagnetic relaxation and methyl-methyl nuclear Overhauser enhancement spectroscopy. Journal of Biomolecular Nmr. 51: 319-28. PMID 21935714 DOI: 10.1007/S10858-011-9559-4  0.306
2011 Ball KA, Phillips AH, Nerenberg PS, Fawzi NL, Wemmer DE, Head-Gordon T. Homogeneous and heterogeneous tertiary structure ensembles of amyloid-β peptides. Biochemistry. 50: 7612-28. PMID 21797254 DOI: 10.1021/Bi200732X  0.771
2011 Fawzi NL, Phillips AH, Ruscio JZ, Doucleff M, Wemmer DE, Head-Gordon T. Structure and dynamics of the Aβ 21-30 peptide from the interplay of NMR experiments and molecular simulations (Journal of the American Chemical Society (2008) 130 (6145-6158) DOI: 10.1021/ja710366c) Journal of the American Chemical Society. 133: 11816. DOI: 10.1021/ja204315n  0.729
2010 Fawzi NL, Ying J, Torchia DA, Clore GM. Kinetics of amyloid beta monomer-to-oligomer exchange by NMR relaxation. Journal of the American Chemical Society. 132: 9948-51. PMID 20604554 DOI: 10.1021/Ja1048253  0.429
2010 Fawzi NL, Doucleff M, Suh JY, Clore GM. Mechanistic details of a protein-protein association pathway revealed by paramagnetic relaxation enhancement titration measurements. Proceedings of the National Academy of Sciences of the United States of America. 107: 1379-84. PMID 20080627 DOI: 10.1073/Pnas.0909370107  0.352
2010 Ruscio JZ, Fawzi NL, Head-Gordon T. How hot? Systematic convergence of the replica exchange method using multiple reservoirs. Journal of Computational Chemistry. 31: 620-7. PMID 19554556 DOI: 10.1002/Jcc.21355  0.694
2008 Fawzi NL, Yap EH, Okabe Y, Kohlstedt KL, Brown SP, Head-Gordon T. Contrasting disease and nondisease protein aggregation by molecular simulation. Accounts of Chemical Research. 41: 1037-47. PMID 18646868 DOI: 10.1021/Ar800062K  0.749
2008 Fawzi NL, Phillips AH, Ruscio JZ, Doucleff M, Wemmer DE, Head-Gordon T. Structure and dynamics of the Abeta(21-30) peptide from the interplay of NMR experiments and molecular simulations. Journal of the American Chemical Society. 130: 6145-58. PMID 18412346 DOI: 10.1021/Ja710366C  0.748
2008 Fawzi NL, Kohlstedt KL, Okabe Y, Head-Gordon T. Protofibril assemblies of the arctic, Dutch, and Flemish mutants of the Alzheimer's Abeta1-40 peptide. Biophysical Journal. 94: 2007-16. PMID 18032553 DOI: 10.1529/Biophysj.107.121467  0.612
2008 Yap EH, Fawzi NL, Head-Gordon T. A coarse-grained alpha-carbon protein model with anisotropic hydrogen-bonding. Proteins. 70: 626-38. PMID 17879350 DOI: 10.1002/Prot.21515  0.675
2007 Lin MS, Fawzi NL, Head-Gordon T. Hydrophobic potential of mean force as a solvation function for protein structure prediction. Structure (London, England : 1993). 15: 727-40. PMID 17562319 DOI: 10.1016/J.Str.2007.05.004  0.673
2007 Fawzi NL, Okabe Y, Yap EH, Head-Gordon T. Determining the critical nucleus and mechanism of fibril elongation of the Alzheimer's Abeta(1-40) peptide. Journal of Molecular Biology. 365: 535-50. PMID 17070840 DOI: 10.1016/J.Jmb.2006.10.011  0.703
2005 Marianayagam NJ, Fawzi NL, Head-Gordon T. Protein folding by distributed computing and the denatured state ensemble. Proceedings of the National Academy of Sciences of the United States of America. 102: 16684-9. PMID 16267133 DOI: 10.1073/Pnas.0506388102  0.588
2005 Fawzi NL, Chubukov V, Clark LA, Brown S, Head-Gordon T. Influence of denatured and intermediate states of folding on protein aggregation. Protein Science : a Publication of the Protein Society. 14: 993-1003. PMID 15772307 DOI: 10.1110/Ps.041177505  0.675
Low-probability matches (unlikely to be authored by this person)
2011 Fawzi NL, Fleissner MR, Anthis NJ, Kálai T, Hideg K, Hubbell WL, Clore GM. A rigid disulfide-linked nitroxide side chain simplifies the quantitative analysis of PRE data. Journal of Biomolecular Nmr. 51: 105-14. PMID 21947919 DOI: 10.1007/S10858-011-9545-X  0.286
2018 Mittag T, Fawzi NL. Protein quality and miRNA slicing get into phase. Nature Cell Biology. 20: 635-637. PMID 29802409 DOI: 10.1038/S41556-018-0113-4  0.281
2017 Boeynaems S, Bogaert E, Kovacs D, Konijnenberg A, Timmerman E, Volkov A, Guharoy M, De Decker M, Jaspers T, Ryan VH, Janke AM, Baatsen P, Vercruysse T, Kolaitis RM, Daelemans D, ... ... Fawzi NL, et al. Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics. Molecular Cell. 65: 1044-1055.e5. PMID 28306503 DOI: 10.1016/J.Molcel.2017.02.013  0.281
2020 Conicella AE, Dignon G, Zerze GH, Schmidt B, D'Ordine AM, Kim Y, Rohatgi R, Ayala YM, Mittal J, Fawzi NL. Alpha-Helical Structure in TDP-43 Tunes Liquid-liquid Phase Separation and Cellular Function Biophysical Journal. 118: 5a-6a. DOI: 10.1016/J.Bpj.2019.11.223  0.278
2020 Zheng W, Dignon GL, Jovic N, Xu X, Regy RM, Fawzi NL, Kim YC, Best RB, Mittal J. Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations. The Journal of Physical Chemistry. B. PMID 33302617 DOI: 10.1021/acs.jpcb.0c10489  0.275
2017 Dempsey ME, Marble HD, Shen T, Fawzi NL, Darling EM. Synthesis and characterization of a magnetically active 19F molecular beacon. Bioconjugate Chemistry. PMID 29272914 DOI: 10.1021/Acs.Bioconjchem.7B00671  0.274
2016 Conicella A, Fawzi N. Backbone 1H, 13C, and 15N Chemical Shift Assignments, HNHA scalar coupling, and 15N backbone relaxation data for TDP-43 C-terminal domain wild type Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr26823  0.274
2023 Maltseva D, Chatterjee S, Yu CC, Brzezinski M, Nagata Y, Gonella G, Murthy AC, Stachowiak JC, Fawzi NL, Parekh SH, Bonn M. Fibril formation and ordering of disordered FUS LC driven by hydrophobic interactions. Nature Chemistry. PMID 37231298 DOI: 10.1038/s41557-023-01221-1  0.271
2019 Murthy A, Burke K, Fawzi N. Backbone (1H and 15N) Chemical Shift Assignments and Relaxation Parameters for the low complexity domain of FUS in the condensed phase Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr27887  0.271
2023 Wang SH, Zheng T, Fawzi NL. Structure and position-specific interactions of prion-like domains in transcription factor Efg1 phase separation. Biorxiv : the Preprint Server For Biology. PMID 37986834 DOI: 10.1101/2023.11.09.566450  0.26
2023 Mohanty P, Rizuan A, Kim YC, Fawzi NL, Mittal J. A complex network of interdomain interactions underlies the conformational ensemble of monomeric TDP-43 and modulates its phase behavior. Protein Science : a Publication of the Protein Society. e4891. PMID 38160320 DOI: 10.1002/pro.4891  0.259
2024 Wang SH, Zheng T, Fawzi NL. Structure and interactions of prion-like domains in transcription factor Efg1 phase separation. Biophysical Journal. PMID 38297837 DOI: 10.1016/j.bpj.2024.01.030  0.258
2021 Chatterjee S, Kan Y, Brzezinski M, Koynov K, Regy RM, Murthy AC, Burke KA, Michels JJ, Mittal J, Fawzi NL, Parekh SH. Reversible Kinetic Trapping of FUS Biomolecular Condensates. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2104247. PMID 34862761 DOI: 10.1002/advs.202104247  0.257
2023 Mohanty P, Shenoy J, Rizuan A, Mercado-Ortiz JF, Fawzi NL, Mittal J. A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305625120. PMID 37579155 DOI: 10.1073/pnas.2305625120  0.255
2020 Frazer C, Staples MI, Kim Y, Hirakawa M, Dowell MA, Johnson NV, Hernday AD, Ryan VH, Fawzi NL, Finkelstein IJ, Bennett RJ. Epigenetic cell fate in Candida albicans is controlled by transcription factor condensates acting at super-enhancer-like elements. Nature Microbiology. PMID 32719507 DOI: 10.1038/S41564-020-0760-7  0.252
2018 Fratta P, Sivakumar P, Humphrey J, Lo K, Ricketts T, Oliveira H, Brito-Armas JM, Kalmar B, Ule A, Yu Y, Birsa N, Bodo C, Collins T, Conicella AE, Mejia Maza A, ... ... Fawzi NL, et al. Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis. The Embo Journal. PMID 29764981 DOI: 10.15252/Embj.201798684  0.251
2018 Kaye EG, Booker M, Kurland JV, Conicella AE, Fawzi NL, Bulyk ML, Tolstorukov MY, Larschan E. Differential Occupancy of Two GA-Binding Proteins Promotes Targeting of the Drosophila Dosage Compensation Complex to the Male X Chromosome. Cell Reports. 22: 3227-3239. PMID 29562179 DOI: 10.1016/J.Celrep.2018.02.098  0.242
2024 Wake N, Weng SL, Zheng T, Wang SH, Kirilenko V, Mittal J, Fawzi NL. Expanding the molecular grammar of polar residues and arginine in FUS prion-like domain phase separation and aggregation. Biorxiv : the Preprint Server For Biology. PMID 38405719 DOI: 10.1101/2024.02.15.580391  0.236
2019 Yanagi KS, Wu Z, Amaya J, Chapkis N, Duffy AM, Hajdarovic KH, Held A, Mathur AD, Russo K, Ryan VH, Steinert BL, Whitt JP, Fallon JR, Fawzi NL, Lipscombe D, et al. Meta-analysis of Genetic Modifiers Reveals Candidate Dysregulated Pathways in Amyotrophic Lateral Sclerosis. Neuroscience. 396: A3-A20. PMID 30594291 DOI: 10.1016/J.Neuroscience.2018.10.033  0.229
2024 Yan X, Kuster D, Mohanty P, Nijssen J, Pombo-García K, Rizuan A, Franzmann TM, Sergeeva A, Passos PM, George L, Wang SH, Shenoy J, Danielson HL, Honigmann A, Ayala YM, ... Fawzi NL, et al. Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates. Biorxiv : the Preprint Server For Biology. PMID 38328053 DOI: 10.1101/2024.01.23.576837  0.228
2021 Bock AS, Murthy AC, Tang WS, Jovic N, Shewmaker F, Mittal J, Fawzi NL. N-terminal acetylation modestly enhances phase separation and reduces aggregation of the low-complexity domain of RNA-binding protein FUS. Protein Science : a Publication of the Protein Society. PMID 33547841 DOI: 10.1002/pro.4029  0.226
2017 Janke A, Burke K, Fawzi N. Degenerate heptads 27-52 of human RNA polymerase II C-terminal domain (DNA-directed RNA polymerase II subunit RPB1): assignments and backbone relaxation Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr27063  0.226
2023 Krevert CS, Chavez D, Chatterjee S, Stelzl LS, Pütz S, Roeters SJ, Rudzinski JF, Fawzi NL, Girard M, Parekh SH, Hunger J. Liquid-Liquid Phase Separation of the Intrinsically Disordered Domain of the Fused in Sarcoma Protein Results in Substantial Slowing of Hydration Dynamics. The Journal of Physical Chemistry Letters. 11224-11234. PMID 38056002 DOI: 10.1021/acs.jpclett.3c02790  0.224
2018 Johnston T, Van Tyne D, Chen RF, Fawzi NL, Kwon B, Kelso MJ, Gilmore MS, Mylonakis E. Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin-resistant Staphylococcus aureus. Scientific Reports. 8: 7062. PMID 29728636 DOI: 10.1038/S41598-018-25571-W  0.211
2023 Sundaram Kumar M, Stallworth KM, Murthy AC, Min Lim S, Li N, Jain A, Munro JB, Fawzi NL, Lagier-Tourenne C, Bosco DA. Interactions between FUS and the C-terminal domain of Nup62 are sufficient for their co-phase separation into amorphous assemblies. Journal of Molecular Biology. 167972. PMID 36690069 DOI: 10.1016/j.jmb.2023.167972  0.204
2021 Perdikari TM, Jovic N, Dignon GL, Kim YC, Fawzi NL, Mittal J. A coarse-grained model for position-specific effects of post-translational modifications on disordered protein phase separation. Biophysical Journal. PMID 33582133 DOI: 10.1016/j.bpj.2021.01.034  0.188
2022 Viola MG, Perdikari TM, Trebino CE, Rahmani N, Mathews KL, Pena CM, Chua XY, Xuan B, LaBreck CJ, Fawzi NL, Camberg JL. An enhancer sequence in the intrinsically disordered region of FtsZ promotes polymer-guided substrate processing by ClpXP protease. Protein Science : a Publication of the Protein Society. 31: e4306. PMID 35481648 DOI: 10.1002/pro.4306  0.186
2021 Newton JC, Naik MT, Li GY, Murphy EL, Fawzi NL, Sedivy JM, Jogl G. Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain. Biophysical Journal. PMID 33798566 DOI: 10.1016/j.bpj.2021.03.028  0.185
2021 Fawzi NL, Parekh SH, Mittal J. Biophysical studies of phase separation integrating experimental and computational methods. Current Opinion in Structural Biology. 70: 78-86. PMID 34144468 DOI: 10.1016/j.sbi.2021.04.004  0.185
2021 Fawzi NL, Parekh SH, Mittal J. Biophysical studies of phase separation integrating experimental and computational methods. Current Opinion in Structural Biology. 70: 78-86. PMID 34144468 DOI: 10.1016/j.sbi.2021.04.004  0.185
2020 Perdikari TM, Murthy AC, Ryan VH, Watters S, Naik MT, Fawzi NL. SARS-CoV-2 nucleocapsid protein phase-separates with RNA and with human hnRNPs. The Embo Journal. e106478. PMID 33200826 DOI: 10.15252/embj.2020106478  0.183
2022 Giambruno R, Grzybowska EA, Fawzi NL, Dormann D. Editorial: The Role of Protein Post-Translational Modifications in Protein-RNA Interactions and RNP Assemblies. Frontiers in Molecular Biosciences. 8: 831810. PMID 35059438 DOI: 10.3389/fmolb.2021.831810  0.177
2020 Ryan VH, Perdikari TM, Naik MT, Saueressig CF, Lins J, Dignon GL, Mittal J, Hart AC, Fawzi NL. Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration. The Embo Journal. e105001. PMID 33349959 DOI: 10.15252/embj.2020105001  0.17
2023 O'Connell LC, Johnson V, Hutton AK, Otis JP, Murthy AC, Liang MC, Wang SH, Fawzi NL, Mowry KL. Intrinsically disordered regions and RNA binding domains contribute to protein enrichment in biomolecular condensates in oocytes. Biorxiv : the Preprint Server For Biology. PMID 37986933 DOI: 10.1101/2023.11.10.566489  0.167
2021 Murthy AC, Tang WS, Jovic N, Janke AM, Seo DH, Perdikari TM, Mittal J, Fawzi NL. Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads. Nature Structural & Molecular Biology. 28: 923-935. PMID 34759379 DOI: 10.1038/s41594-021-00677-4  0.157
2020 Perdikari TM, Murthy AC, Ryan VH, Watters S, Naik MT, Fawzi NL. SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins. Biorxiv : the Preprint Server For Biology. PMID 32577653 DOI: 10.1101/2020.06.09.141101  0.153
2023 Guo L, Mann JR, Mauna JC, Copley KE, Wang H, Rubien JD, Odeh HM, Lin J, Lee BL, Ganser L, Robinson E, Kim KM, Murthy AC, Paul T, Portz B, ... ... Fawzi NL, et al. Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains. Biorxiv : the Preprint Server For Biology. PMID 37732211 DOI: 10.1101/2023.09.04.555754  0.147
2024 Ray M, Zaborowsky J, Mahableshwarkar P, Vaidyanathan S, Shum J, Viswanathan R, Huang A, Wang SH, Johnson V, Wake N, Conard AM, Conicella AE, Puterbaugh R, Fawzi NL, Larschan E. Dual DNA/RNA-binding factor regulates dynamics of hnRNP splicing condensates. Biorxiv : the Preprint Server For Biology. PMID 38260450 DOI: 10.1101/2024.01.11.575216  0.141
2021 Hallegger M, Chakrabarti AM, Lee FCY, Lee BL, Amalietti AG, Odeh HM, Copley KE, Rubien JD, Portz B, Kuret K, Huppertz I, Rau F, Patani R, Fawzi NL, Shorter J, et al. TDP-43 condensation properties specify its RNA-binding and regulatory repertoire. Cell. PMID 34380047 DOI: 10.1016/j.cell.2021.07.018  0.138
2021 Owen I, Yee D, Wyne H, Perdikari TM, Johnson V, Smyth J, Kortum R, Fawzi NL, Shewmaker F. The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation. Journal of Cell Science. PMID 34357401 DOI: 10.1242/jcs.258578  0.136
2021 Yuan F, Alimohamadi H, Bakka B, Trementozzi AN, Day KJ, Fawzi NL, Rangamani P, Stachowiak JC. Membrane bending by protein phase separation. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33688043 DOI: 10.1073/pnas.2017435118  0.125
2021 Lin YC, Kumar MS, Ramesh N, Anderson EN, Nguyen AT, Kim B, Cheung S, McDonough JA, Skarnes WC, Lopez-Gonzalez R, Landers JE, Fawzi NL, Mackenzie IRA, Lee EB, Nickerson JA, et al. Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway. Nature Neuroscience. PMID 34059832 DOI: 10.1038/s41593-021-00859-9  0.098
2023 Staples MI, Frazer C, Fawzi NL, Bennett RJ. Phase separation in fungi. Nature Microbiology. PMID 36782025 DOI: 10.1038/s41564-022-01314-6  0.091
1999 Ghareeb A, Khalifa SF, Fawzi N. Molecular systematics of some Cassia species Cytologia. 64: 11-16.  0.084
2021 Duan J, Rieder L, Colonnetta MM, Huang A, Mckenney M, Watters S, Deshpande G, Jordan W, Fawzi N, Larschan E. CLAMP and Zelda function together to promote zygotic genome activation. Elife. 10. PMID 34342574 DOI: 10.7554/eLife.69937  0.062
2013 Fawzi N, Vasudevan R, Ismail P, Alwi M, Aziz AFA, Almeamar H, Mohamad NA, Etemad A. Genotyping of GATA4 gene variant (G296S) in Malaysian congenital heart disease subjects by real-time PCR high resolution melting analysis Journal of Medical Biochemistry. 32: 152-157. DOI: 10.2478/jomb-2013-0006  0.054
2013 Almeamar HA, Ramachandran V, Ismail P, Nadkarni P, Fawzi N. Analysis of partial AZFc deletions in Malaysian infertile male subjects. Systems Biology in Reproductive Medicine. 59: 99-107. PMID 23231020 DOI: 10.3109/19396368.2012.748851  0.052
2001 Al-Enezi G, Ettouney H, El-Dessouky H, Fawzi N. Solubility of sulfur dioxide in seawater Industrial and Engineering Chemistry Research. 40: 1434-1441.  0.049
1999 Al-Enezi G, Fawzi N, Elkamel A. Development of regression models to control product yields and properties of the fluid catalytic cracking process Petroleum Science and Technology. 17: 535-552.  0.045
2004 Al-Enezi G, Hamoda MF, Fawzi N. Ion exchange extraction of heavy metals from wastewater sludges. Journal of Environmental Science and Health. Part a, Toxic/Hazardous Substances & Environmental Engineering. 39: 455-64. PMID 15027828 DOI: 10.1081/ESE-120027536  0.034
1994 Austin JR, Stewart KL, Fawzi N. Squamous cell carcinoma of the external auditory canal. Therapeutic prognosis based on a proposed staging system. Archives of Otolaryngology--Head & Neck Surgery. 120: 1228-32. PMID 7917206 DOI: 10.1001/archotol.1994.01880350036007  0.033
2004 Al Enezi G, Hamoda MF, Fawzi N. Heavy metals content of municipal wastewater and sludges in Kuwait. Journal of Environmental Science and Health. Part a, Toxic/Hazardous Substances & Environmental Engineering. 39: 397-407. PMID 15027823 DOI: 10.1081/ESE-120027531  0.023
2003 Al-Enezi G, Fawzi N. Design consideration of RO units: Case studies Desalination. 153: 281-286. DOI: 10.1016/S0011-9164(02)01147-5  0.01
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