Yuval Blat - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Moslin R, Gardner D, Santella J, Zhang Y, Duncia JV, Liu C, Lin J, Tokarski JS, Strnad J, Pedicord D, Chen J, Blat Y, Zupa-Fernandez A, Cheng L, Sun H, et al. Identification of imidazo[1,2-]pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling. Medchemcomm. 8: 700-712. PMID 30108788 DOI: 10.1039/C6Md00560H  0.305
2016 Chupak LS, Zheng X, Hu S, Huang Y, Ding M, Lewis MA, Westphal RS, Blat Y, McClure A, Gentles RG. Structure activity relationship studies on chemically non-reactive glycine sulfonamide inhibitors of diacylglycerol lipase. Bioorganic & Medicinal Chemistry. PMID 26917221 DOI: 10.1016/J.Bmc.2016.02.006  0.323
2015 Chaudhry C, Davis J, Zhang Y, Posy S, Lei M, Shen H, Yan C, Devaux B, Zhang L, Blat Y, Metzler W, Borzilleri RM, Talbott RL. Building HTRF assays for characterization of bivalent inhibitors of an Inhibitor of Apoptosis Protein target. Analytical Biochemistry. PMID 26743718 DOI: 10.1016/J.Ab.2015.11.026  0.359
2015 Tokarski JS, Zupa-Fernandez A, Tredup JA, Pike K, Chang C, Xie D, Cheng L, Pedicord D, Muckelbauer J, Johnson SR, Wu S, Edavettal SC, Hong Y, Witmer MR, Elkin LL, ... Blat Y, et al. Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. The Journal of Biological Chemistry. 290: 11061-74. PMID 25762719 DOI: 10.1074/Jbc.M114.619502  0.314
2014 Appiah KK, Blat Y, Robertson BJ, Pearce BC, Pedicord DL, Gentles RG, Yu XC, Mseeh F, Nguyen N, Swaffield JC, Harden DG, Westphal RS, Banks MN, O'Connell JC. Identification of small molecules that selectively inhibit diacylglycerol lipase-α activity. Journal of Biomolecular Screening. 19: 595-605. PMID 24241710 DOI: 10.1177/1087057113511111  0.304
2010 Blat Y. Non-competitive inhibition by active site binders. Chemical Biology & Drug Design. 75: 535-40. PMID 20374252 DOI: 10.1111/J.1747-0285.2010.00972.X  0.348
2010 Fanslau C, Pedicord D, Nagulapalli S, Gray H, Pang S, Jayaraman L, Lippy J, Blat Y. An electrophoretic mobility shift assay for the identification and kinetic analysis of acetyl transferase inhibitors. Analytical Biochemistry. 402: 65-8. PMID 20338149 DOI: 10.1016/J.Ab.2010.03.025  0.321
2007 Sahni-Arya B, Flynn MJ, Bergeron L, Salyan ME, Pedicord DL, Golla R, Ma Z, Wang H, Seethala R, Wu SC, Li JJ, Nayeem A, Gates C, Hamann LG, Gordon DA, ... Blat Y, et al. Cofactor-specific modulation of 11beta-hydroxysteroid dehydrogenase 1 inhibitor potency. Biochimica Et Biophysica Acta. 1774: 1184-91. PMID 17707701 DOI: 10.1016/J.Bbapap.2007.07.005  0.303
2002 Blat Y, Protacio RU, Hunter N, Kleckner N. Physical and functional interactions among basic chromosome organizational features govern early steps of meiotic chiasma formation. Cell. 111: 791-802. PMID 12526806 DOI: 10.1016/S0092-8674(02)01167-4  0.534
2002 Blat Y, Meredith JE, Wang Q, Bradley JD, Thompson LA, Olson RE, Stern AM, Seiffert D. Mutations at the P1' position of Notch1 decrease intracellular domain stability rather than cleavage by gamma-secretase. Biochemical and Biophysical Research Communications. 299: 569-73. PMID 12459176 DOI: 10.1016/S0006-291X(02)02705-5  0.321
2002 Bachant J, Alcasabas A, Blat Y, Kleckner N, Elledge SJ. The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II. Molecular Cell. 9: 1169-82. PMID 12086615 DOI: 10.1016/S1097-2765(02)00543-9  0.516
1999 Blat Y, Kleckner N. Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region. Cell. 98: 249-59. PMID 10428036 DOI: 10.1016/S0092-8674(00)81019-3  0.52
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