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Year Citation  Score
2023 Mangkalaphiban K, Ganesan R, Jacobson A. Direct and indirect consequences of deletion in the regulation of translation initiation, translation termination, and mRNA decay. Biorxiv : the Preprint Server For Biology. PMID 37398227 DOI: 10.1101/2023.05.31.543082  0.573
2022 Ganesan R, Mangkalaphiban K, Baker R, He F, Jacobson A. Ribosome-bound Upf1 forms distinct 80S complexes and conducts mRNA surveillance. Rna (New York, N.Y.). PMID 36192133 DOI: 10.1261/rna.079416.122  0.538
2022 He F, Jacobson A. Eukaryotic mRNA decapping factors: molecular mechanisms and activity. The Febs Journal. PMID 36098474 DOI: 10.1111/febs.16626  0.575
2021 Mangkalaphiban K, He F, Ganesan R, Wu C, Baker R, Jacobson A. Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae. Plos Genetics. 17: e1009538. PMID 33878104 DOI: 10.1371/journal.pgen.1009538  0.529
2020 Luban J, Sattler R, Mühlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, ... ... Jacobson A, et al. The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. Virus Research. 198246. PMID 33249060 DOI: 10.1016/j.virusres.2020.198246  0.712
2020 Wu C, Roy B, He F, Yan K, Jacobson A. Poly(A)-Binding Protein Regulates the Efficiency of Translation Termination. Cell Reports. 33: 108399. PMID 33207198 DOI: 10.1016/j.celrep.2020.108399  0.489
2020 Luban J, Sattler R, Mühlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, ... ... Jacobson A, et al. The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. Biorxiv : the Preprint Server For Biology. PMID 32793904 DOI: 10.1101/2020.08.05.238394  0.712
2019 Zeidan Q, He F, Zhang F, Zhang H, Jacobson A, Hinnebusch AG. Correction: Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo. Plos Genetics. 15: e1008299. PMID 31335872 DOI: 10.1371/journal.pgen.1008299  0.484
2018 Ng MY, Zhang H, Weil A, Singh V, Jamiolkowski R, Baradaran-Heravi A, Roberge M, Jacobson A, Friesen W, Welch E, Goldman YE, Cooperman BS. New Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery. Acs Medicinal Chemistry Letters. 9: 1285-1291. PMID 30613341 DOI: 10.1021/Acsmedchemlett.8B00472  0.695
2018 Ganesan R, Leszyk J, Jacobson A. Selective profiling of ribosomes associated with yeast Upf proteins. Methods (San Diego, Calif.). PMID 30593864 DOI: 10.1016/J.Ymeth.2018.12.008  0.402
2018 Zeidan Q, He F, Zhang F, Zhang H, Jacobson A, Hinnebusch AG. Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo. Plos Genetics. 14: e1007806. PMID 30532217 DOI: 10.1371/Journal.Pgen.1007806  0.675
2018 He F, Celik A, Wu C, Jacobson A. General decapping activators target different subsets of inefficiently translated mRNAs. Elife. 7. PMID 30520724 DOI: 10.7554/Elife.34409  0.598
2018 He F, Celik A, Baker R, Jacobson A. High-Resolution Profiling of NMD Targets in Yeast. Methods in Enzymology. 612: 147-181. PMID 30502940 DOI: 10.1016/Bs.Mie.2018.09.005  0.428
2018 Cao L, Weetall M, Trotta C, Cintron K, Ma J, Kim MJ, Furia B, Romfo C, Graci JD, Li W, Du J, Sheedy J, Hedrick J, Risher N, Yeh S, ... ... Jacobson A, et al. Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties. Molecular Cancer Therapeutics. PMID 30352802 DOI: 10.1158/1535-7163.Mct-18-0863  0.601
2018 He F, Celik A, Wu C, Jacobson A. Author response: General decapping activators target different subsets of inefficiently translated mRNAs Elife. DOI: 10.7554/Elife.34409.031  0.498
2017 Celik A, He F, Jacobson A. NMD monitors translational fidelity 24/7. Current Genetics. PMID 28536849 DOI: 10.1007/S00294-017-0709-4  0.662
2017 Jacobson A. The moment when translational control had a theory of everything. Nature Reviews. Molecular Cell Biology. PMID 28400611 DOI: 10.1038/Nrm.2017.33  0.335
2017 Celik A, Baker R, He F, Jacobson A. High Resolution Profiling of NMD Targets in Yeast Reveals Translational Fidelity as a Basis for Substrate Selection. Rna (New York, N.Y.). PMID 28209632 DOI: 10.1261/Rna.060541.116  0.562
2016 Roy B, Friesen WJ, Tomizawa Y, Leszyk JD, Zhuo J, Johnson B, Dakka J, Trotta CR, Xue X, Mutyam V, Keeling KM, Mobley JA, Rowe SM, Bedwell DM, Welch EM, ... Jacobson A, et al. Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression. Proceedings of the National Academy of Sciences of the United States of America. PMID 27702906 DOI: 10.1073/Pnas.1605336113  0.807
2016 Dong S, Jacobson A, He F. Correction: Degradation of YRA1 Pre-mRNA in the Cytoplasm Requires Translational Repression, Multiple Modular Intronic Elements, Edc3p, and Mex67p. Plos Biology. 14: e1002470. PMID 27171161 DOI: 10.1371/journal.pbio.1002470  0.4
2015 He F, Jacobson A. Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story. Annual Review of Genetics. PMID 26436458 DOI: 10.1146/Annurev-Genet-112414-054639  0.64
2015 He F, Jacobson A. Control of mRNA decapping by positive and negative regulatory elements in the Dcp2 C-terminal domain. Rna (New York, N.Y.). 21: 1633-47. PMID 26184073 DOI: 10.1261/Rna.052449.115  0.451
2015 Roy B, Leszyk JD, Mangus DA, Jacobson A. Nonsense suppression by near-cognate tRNAs employs alternative base pairing at codon positions 1 and 3. Proceedings of the National Academy of Sciences of the United States of America. 112: 3038-43. PMID 25733896 DOI: 10.1073/Pnas.1424127112  0.824
2015 Celik A, Kervestin S, Jacobson A. NMD: At the crossroads between translation termination and ribosome recycling. Biochimie. 114: 2-9. PMID 25446649 DOI: 10.1016/J.Biochi.2014.10.027  0.602
2014 Fourati Z, Roy B, Millan C, Coureux PD, Kervestin S, van Tilbeurgh H, He F, Usón I, Jacobson A, Graille M. A highly conserved region essential for NMD in the Upf2 N-terminal domain. Journal of Molecular Biology. 426: 3689-702. PMID 25277656 DOI: 10.1016/j.jmb.2014.09.015  0.506
2014 Tsanova B, Spatrick P, Jacobson A, van Hoof A. The RNA exosome affects iron response and sensitivity to oxidative stress. Rna (New York, N.Y.). 20: 1057-67. PMID 24860016 DOI: 10.1261/Rna.043257.113  0.37
2014 He F, Li C, Roy B, Jacobson A. Yeast Edc3 targets RPS28B mRNA for decapping by binding to a 3' untranslated region decay-inducing regulatory element. Molecular and Cellular Biology. 34: 1438-51. PMID 24492965 DOI: 10.1128/Mcb.01584-13  0.638
2013 He F, Ganesan R, Jacobson A. Intra- and intermolecular regulatory interactions in Upf1, the RNA helicase central to nonsense-mediated mRNA decay in yeast. Molecular and Cellular Biology. 33: 4672-84. PMID 24100012 DOI: 10.1128/Mcb.01136-13  0.451
2013 Roy B, Jacobson A. The intimate relationships of mRNA decay and translation. Trends in Genetics : Tig. 29: 691-9. PMID 24091060 DOI: 10.1016/J.Tig.2013.09.002  0.636
2013 Min EE, Roy B, Amrani N, He F, Jacobson A. Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit. Rna (New York, N.Y.). 19: 1105-15. PMID 23801788 DOI: 10.1261/Rna.039396.113  0.796
2013 Peltz SW, Morsy M, Welch EM, Jacobson A. Ataluren as an agent for therapeutic nonsense suppression. Annual Review of Medicine. 64: 407-25. PMID 23215857 DOI: 10.1146/Annurev-Med-120611-144851  0.833
2012 Kervestin S, Jacobson A. NMD: a multifaceted response to premature translational termination. Nature Reviews. Molecular Cell Biology. 13: 700-12. PMID 23072888 DOI: 10.1038/Nrm3454  0.637
2012 Kervestin S, Li C, Buckingham R, Jacobson A. Testing the faux-UTR model for NMD: analysis of Upf1p and Pab1p competition for binding to eRF3/Sup35p. Biochimie. 94: 1560-71. PMID 22227378 DOI: 10.1016/J.Biochi.2011.12.021  0.568
2010 Ghosh S, Jacobson A. RNA decay modulates gene expression and controls its fidelity. Wiley Interdisciplinary Reviews. Rna. 1: 351-61. PMID 21132108 DOI: 10.1002/Wrna.25  0.522
2010 Ghosh S, Ganesan R, Amrani N, Jacobson A. Translational competence of ribosomes released from a premature termination codon is modulated by NMD factors. Rna (New York, N.Y.). 16: 1832-47. PMID 20675403 DOI: 10.1261/Rna.1987710  0.832
2010 Johansson MJ, Jacobson A. Nonsense-mediated mRNA decay maintains translational fidelity by limiting magnesium uptake. Genes & Development. 24: 1491-5. PMID 20634315 DOI: 10.1101/Gad.1930710  0.637
2010 Dong S, Jacobson A, He F. Degradation of YRA1 Pre-mRNA in the cytoplasm requires translational repression, multiple modular intronic elements, Edc3p, and Mex67p. Plos Biology. 8: e1000360. PMID 20463951 DOI: 10.1371/Journal.Pbio.1000360  0.652
2009 Peltz SW, Welch EM, Trotta CR, Davis T, Jacobson A. Targeting post-transcriptional control for drug discovery. Rna Biology. 6: 329-34. PMID 19574739 DOI: 10.4161/Rna.6.3.8953  0.815
2009 Peltz SW, Welch EM, Jacobson A, Trotta CR, Naryshkin N, Sweeney HL, Bedwell DM. Nonsense suppression activity of PTC124 (ataluren). Proceedings of the National Academy of Sciences of the United States of America. 106: E64; author reply E6. PMID 19506240 DOI: 10.1073/Pnas.0901936106  0.735
2009 Kerem E, Kerem B, Welch EM, Trotta C, Weetall M, Miller L, Jacobson A, Peltz SW. PTC124 for cystic fibrosis - Authors' reply The Lancet. 373: 1426-1427. PMID 19394530 DOI: 10.1016/S0140-6736(09)60820-5  0.71
2008 He F, Amrani N, Johansson MJ, Jacobson A. Chapter 6. Qualitative and quantitative assessment of the activity of the yeast nonsense-mediated mRNA decay pathway. Methods in Enzymology. 449: 127-47. PMID 19215756 DOI: 10.1016/S0076-6879(08)02406-3  0.833
2008 Amrani N, Ghosh S, Mangus DA, Jacobson A. Translation factors promote the formation of two states of the closed-loop mRNP. Nature. 453: 1276-80. PMID 18496529 DOI: 10.1038/Nature06974  0.841
2007 Johansson MJ, He F, Spatrick P, Li C, Jacobson A. Association of yeast Upf1p with direct substrates of the NMD pathway. Proceedings of the National Academy of Sciences of the United States of America. 104: 20872-7. PMID 18087042 DOI: 10.1073/Pnas.0709257105  0.616
2007 Wu C, Amrani N, Jacobson A, Sachs MS. The use of fungal in vitro systems for studying translational regulation. Methods in Enzymology. 429: 203-25. PMID 17913625 DOI: 10.1016/S0076-6879(07)29010-X  0.732
2007 Welch EM, Barton ER, Zhuo J, Tomizawa Y, Friesen WJ, Trifillis P, Paushkin S, Patel M, Trotta CR, Hwang S, Wilde RG, Karp G, Takasugi J, Chen G, Jones S, ... ... Jacobson A, et al. PTC124 targets genetic disorders caused by nonsense mutations. Nature. 447: 87-91. PMID 17450125 DOI: 10.1038/Nature05756  0.776
2007 Dong S, Li C, Zenklusen D, Singer RH, Jacobson A, He F. YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA. Molecular Cell. 25: 559-73. PMID 17317628 DOI: 10.1016/J.Molcel.2007.01.012  0.648
2007 Jacobson A, Izaurralde E. 23 Nonsense-mediated mRNA Decay: From Yeast to Metazoans Cold Spring Harbor Monograph Archive. 48: 655-687. DOI: 10.1101/087969767.48.655  0.65
2006 Amrani N, Sachs MS, Jacobson A. Early nonsense: mRNA decay solves a translational problem. Nature Reviews. Molecular Cell Biology. 7: 415-25. PMID 16723977 DOI: 10.1038/Nrm1942  0.837
2006 Amrani N, Dong S, He F, Ganesan R, Ghosh S, Kervestin S, Li C, Mangus DA, Spatrick P, Jacobson A. Aberrant termination triggers nonsense-mediated mRNA decay. Biochemical Society Transactions. 34: 39-42. PMID 16246174 DOI: 10.1042/Bst0340039  0.858
2006 Amrani N, Dong S, He F, Ganesan R, Ghosh S, Kervestin S, Li C, Mangus D, Spatrick P, Jacobson A. Aberrant termination triggers nonsense-mediated mRNA decay Biochemical Society Transactions. 34: 39-42. DOI: 10.1042/BST0340039  0.86
2005 Gaba A, Jacobson A, Sachs MS. Ribosome occupancy of the yeast CPA1 upstream open reading frame termination codon modulates nonsense-mediated mRNA decay. Molecular Cell. 20: 449-60. PMID 16285926 DOI: 10.1016/J.Molcel.2005.09.019  0.604
2005 Jacobson A. The end justifies the means. Nature Structural & Molecular Biology. 12: 474-5. PMID 15933730 DOI: 10.1038/Nsmb0605-474  0.408
2004 Amrani N, Ganesan R, Kervestin S, Mangus DA, Ghosh S, Jacobson A. A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay. Nature. 432: 112-8. PMID 15525991 DOI: 10.1038/Nature03060  0.869
2004 Ross PL, Huang YN, Marchese JN, Williamson B, Parker K, Hattan S, Khainovski N, Pillai S, Dey S, Daniels S, Purkayastha S, Juhasz P, Martin S, Bartlet-Jones M, He F, ... Jacobson A, et al. Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Molecular & Cellular Proteomics : McP. 3: 1154-69. PMID 15385600 DOI: 10.1074/Mcp.M400129-Mcp200  0.368
2004 Jacobson A. Regulation of mRNA decay: decapping goes solo. Molecular Cell. 15: 1-2. PMID 15225542 DOI: 10.1016/J.Molcel.2004.06.031  0.545
2004 Mangus DA, Evans MC, Agrin NS, Smith M, Gongidi P, Jacobson A. Positive and negative regulation of poly(A) nuclease. Molecular and Cellular Biology. 24: 5521-33. PMID 15169912 DOI: 10.1128/Mcb.24.12.5521-5533.2004  0.811
2004 Mangus DA, Smith MM, McSweeney JM, Jacobson A. Identification of factors regulating poly(A) tail synthesis and maturation. Molecular and Cellular Biology. 24: 4196-206. PMID 15121841 DOI: 10.1128/Mcb.24.10.4196-4206.2004  0.836
2004 Parker KC, Patterson D, Williamson B, Marchese J, Graber A, He F, Jacobson A, Juhasz P, Martin S. Depth of proteome issues: a yeast isotope-coded affinity tag reagent study. Molecular & Cellular Proteomics : McP. 3: 625-59. PMID 15047794 DOI: 10.1074/Mcp.M300110-Mcp200  0.331
2003 He F, Li X, Spatrick P, Casillo R, Dong S, Jacobson A. Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast. Molecular Cell. 12: 1439-52. PMID 14690598 DOI: 10.1016/S1097-2765(03)00446-5  0.61
2003 Mangus DA, Evans MC, Jacobson A. Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression. Genome Biology. 4: 223. PMID 12844354 DOI: 10.1186/Gb-2003-4-7-223  0.855
2003 Maderazo AB, Belk JP, He F, Jacobson A. Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution. Molecular and Cellular Biology. 23: 842-51. PMID 12529390 DOI: 10.1128/Mcb.23.3.842-851.2003  0.654
2002 Sachs MS, Wang Z, Gaba A, Fang P, Belk J, Ganesan R, Amrani N, Jacobson A. Toeprint analysis of the positioning of translation apparatus components at initiation and termination codons of fungal mRNAs. Methods (San Diego, Calif.). 26: 105-14. PMID 12054887 DOI: 10.1016/S1046-2023(02)00013-0  0.816
2002 Düvel K, Valerius O, Mangus DA, Jacobson A, Braus GH. Replacement of the yeast TRP4 3' untranslated region by a hammerhead ribozyme results in a stable and efficiently exported mRNA that lacks a poly(A) tail. Rna (New York, N.Y.). 8: 336-44. PMID 12003493 DOI: 10.1017/S1355838202021039  0.865
2001 Bond AT, Mangus DA, He F, Jacobson A. Absence of Dbp2p alters both nonsense-mediated mRNA decay and rRNA processing. Molecular and Cellular Biology. 21: 7366-79. PMID 11585918 DOI: 10.1128/Mcb.21.21.7366-7379.2001  0.844
2001 He F, Jacobson A. Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs Molecular and Cellular Biology. 21: 1515-1530. PMID 11238889 DOI: 10.1128/Mcb.21.5.1515-1530.2001  0.65
2000 Bhattacharya A, Czaplinski K, Trifillis P, He F, Jacobson A, Peltz SW. Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay Rna. 6: 1226-1235. PMID 10999600 DOI: 10.1017/S1355838200000546  0.711
2000 Knight JE, Narus EN, Martin SL, Jacobson A, Barnes BM, Boyer BB. mRNA stability and polysome loss in hibernating Arctic ground squirrels (Spermophilus parryii). Molecular and Cellular Biology. 20: 6374-9. PMID 10938114 DOI: 10.1128/Mcb.20.17.6374-6379.2000  0.586
2000 Welch EM, Jacobson A. An internal open reading frame triggers nonsense-mediated decay of the yeast SPT10 mRNA. The Embo Journal. 18: 6134-45. PMID 10545123 DOI: 10.1093/Emboj/18.21.6134  0.836
2000 Maderazo AB, He F, Mangus DA, Jacobson A. Upf1p Control of Nonsense mRNA Translation Is Regulated by Nmd2p and Upf3p Molecular and Cellular Biology. 20: 4591-4603. DOI: 10.1128/Mcb.20.13.4591-4603.2000  0.861
2000 Jacobson A, Peltz SW. 29 Destabilization of Nonsense-containing Transcripts in Saccharomyces cerevisiae Cold Spring Harbor Monograph Archive. 39: 827-847. DOI: 10.1101/087969618.39.827  0.684
1999 Belk JP, He F, Jacobson A. Overexpression of truncated Nmd3p inhibits protein synthesis in yeast. Rna (New York, N.Y.). 5: 1055-70. PMID 10445880 DOI: 10.1017/S1355838299990027  0.541
1999 Mangus DA, Jacobson A. Linking mRNA turnover and translation: assessing the polyribosomal association of mRNA decay factors and degradative intermediates. Methods (San Diego, Calif.). 17: 28-37. PMID 10075880 DOI: 10.1006/Meth.1998.0704  0.863
1999 Jacobson A, Peltz SW. Tools for turnover: methods for analysis of mRNA stability in eukaryotic cells. Methods (San Diego, Calif.). 17: 1-2. PMID 10075876 DOI: 10.1006/Meth.1998.0700  0.705
1998 Mangus DA, Amrani N, Jacobson A. Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation. Molecular and Cellular Biology. 18: 7383-96. PMID 9819425 DOI: 10.1128/Mcb.18.12.7383  0.856
1998 Zuk D, Jacobson A. A single amino acid substitution in yeast eIF-5A results in mRNA stabilization The Embo Journal. 17: 2914-2925. PMID 9582285 DOI: 10.1093/Emboj/17.10.2914  0.827
1997 He F, Brown AH, Jacobson A. Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Molecular and Cellular Biology. 17: 1580-94. PMID 9032286 DOI: 10.1128/MCB.17.3.1580  0.403
1996 Jacobson A, Peltz SW. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. Annual Review of Biochemistry. 65: 693-739. PMID 8811193 DOI: 10.1146/Annurev.Bi.65.070196.003401  0.805
1996 Hennigan AN, Jacobson A. Functional mapping of the translation-dependent instability element of yeast MATalpha1 mRNA. Molecular and Cellular Biology. 16: 3833-3843. DOI: 10.1128/Mcb.16.7.3833  0.597
1995 He F, Jacobson A. Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen Genes and Development. 9: 437-454. PMID 7883168 DOI: 10.1101/Gad.9.4.437  0.57
1994 Peltz SW, He F, Welch E, Jacobson A. Nonsense-mediated mRNA decay in yeast. Progress in Nucleic Acid Research and Molecular Biology. 47: 271-98. PMID 8016322 DOI: 10.1016/S0079-6603(08)60254-8  0.863
1993 Peltz SW, Brown AH, Jacobson A. mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor. Genes & Development. 7: 1737-54. PMID 8370523 DOI: 10.1101/Gad.7.9.1737  0.744
1993 He F, Peltz SW, Donahue JL, Rosbash M, Jacobson A. Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant. Proceedings of the National Academy of Sciences of the United States of America. 90: 7034-8. PMID 8346213 DOI: 10.1073/Pnas.90.15.7034  0.795
1993 Peltz SW, Jacobson A. mRNA stability: in trans-it. Current Opinion in Cell Biology. 4: 979-83. PMID 1485969 DOI: 10.1016/0955-0674(92)90129-Z  0.763
1993 Higgins CF, Peltz SW, Jacobson A. Turnover of mRNA in prokaryotes and lower eukaryotes. Current Opinion in Genetics & Development. 2: 739-47. PMID 1281028 DOI: 10.1016/S0959-437X(05)80134-0  0.746
1992 Leeds P, Peltz SW, Jacobson A, Culbertson MR. The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon. Genes & Development. 5: 2303-14. PMID 1748286 DOI: 10.1101/Gad.5.12A.2303  0.789
1992 Herrick D, Jacobson A. A coding region segment is necessary, but not sufficient for rapid decay of the HIS3 mRNA in yeast. Gene. 114: 35-41. PMID 1587483 DOI: 10.1016/0378-1119(92)90704-S  0.825
1992 Peltz SW, Donahue JL, Jacobson A. A mutation in the tRNA nucleotidyltransferase gene promotes stabilization of mRNAs in Saccharomyces cerevisiae Molecular and Cellular Biology. 12: 5778-5784. PMID 1448105 DOI: 10.1128/Mcb.12.12.5778  0.769
1992 Heaton B, Decker C, Muhlrad D, Donahue J, Jacobson A, Parker R. Analysis of chimeric mRNAs derived from the STE3 mRNA identifies multiple regions within yeast mRNAs that modulate mRNA decay Nucleic Acids Research. 20: 5365-5373. PMID 1437553 DOI: 10.1093/Nar/20.20.5365  0.694
1992 Higgins CF, Peltz SW, Jacobson A. Turnover of mRNA in prokaryotes and lower eukaryotes Current Biology. 2: 536. DOI: 10.1016/0960-9822(92)90019-7  0.77
1991 Steel LF, Jacobson A. Sequence elements that affect mRNA translational activity in developing Dictyostelium cells. Developmental Genetics. 12: 98-103. PMID 2049885 DOI: 10.1002/Dvg.1020120117  0.623
1991 Parker R, Herrick D, Peltz SW, Jacobson A. Measurement of mRNA decay rates in Saccharomyces cerevisiae. Methods in Enzymology. 194: 415-23. PMID 2005800 DOI: 10.1016/0076-6879(91)94032-8  0.861
1990 Herrick D, Parker R, Jacobson A. Identification and comparison of stable and unstable mRNAs in Saccharomyces cerevisiae. Molecular and Cellular Biology. 10: 2269-84. PMID 2183028 DOI: 10.1128/Mcb.10.5.2269  0.848
1990 Parker R, Jacobson A. Translation and a 42-nucleotide segment within the coding region of the mRNA encoded by the MAT alpha 1 gene are involved in promoting rapid mRNA decay in yeast Proceedings of the National Academy of Sciences of the United States of America. 87: 2780-2784. PMID 2181450 DOI: 10.1073/Pnas.87.7.2780  0.633
1990 Munroe D, Jacobson A. Tales of poly(A): a review Gene. 91: 151-158. PMID 1976572 DOI: 10.1016/0378-1119(90)90082-3  0.808
1990 Munroe D, Jacobson A. mRNA poly(A) tail, a 3' enhancer of translational initiation. Molecular and Cellular Biology. 10: 3441-55. PMID 1972543 DOI: 10.1128/Mcb.10.7.3441  0.817
1988 Shapiro RA, Herrick D, Manrow RE, Blinder D, Jacobson A. Determinants of mRNA stability in Dictyostelium discoideum amoebae: differences in poly(A) tail length, ribosome loading, and mRNA size cannot account for the heterogeneity of mRNA decay rates. Molecular and Cellular Biology. 8: 1957-69. PMID 2898728 DOI: 10.1128/Mcb.8.5.1957  0.84
1988 Manrow RE, Jacobson A. mRNA decay rates in late-developing Dictyostelium discoideum cells are heterogeneous, and cyclic AMP does not act directly to stabilize cell-type-specific mRNAs. Molecular and Cellular Biology. 8: 4088-97. PMID 2847029 DOI: 10.1128/Mcb.8.10.4088  0.595
1988 Steel LF, Smyth A, Jacobson A. Nucleotide sequence and characterization of the transcript of a Dictyostelium ribosomal protein gene. Nucleic Acids Research. 15: 10285-98. PMID 2827119 DOI: 10.1093/Nar/15.24.10285  0.582
1988 Manrow RE, Shapiro RA, Herrick D, Steel LF, Blinder D, Jacobson A. Regulation of mRNA stability and the poly(A) problem in Dictyostelium discoideum. Developmental Genetics. 9: 403-19. PMID 2468435 DOI: 10.1002/dvg.1020090420  0.834
1988 Steel LF, Jacobson A. Post-transcriptional regulation of ribosomal protein gene expression during development inDictyostelium discoideum Developmental Genetics. 9: 421-434. DOI: 10.1002/Dvg.1020090421  0.555
1987 Jacobson A. Purification and fractionation of poly(A)+ RNA Methods in Enzymology. 152: 254-261. PMID 2443797 DOI: 10.1016/0076-6879(87)52028-6  0.61
1986 Steel LF, Jacobson A. Ribosomal proteins are encoded by single copy genes in Dictyostelium discoideum. Gene. 41: 165-72. PMID 3011594 DOI: 10.1016/0378-1119(86)90095-8  0.381
1986 Manrow RE, Jacobson A. Identification and characterization of developmentally regulated mRNP proteins of Dictyostelium discoideum Developmental Biology. 116: 213-227. DOI: 10.1016/0012-1606(86)90058-8  0.374
1985 Firtel RA, Silan C, Ward TE, Howard P, Metz BA, Nellen W, Jacobson A. Extrachromosomal replication of shuttle vectors in Dictyostelium discoideum. Molecular and Cellular Biology. 5: 3241-50. PMID 3018510 DOI: 10.1128/MCB.5.11.3241  0.44
1984 Palatnik CM, Wilkins C, Jacobson A. Translational control during early dictyostelium development: Possible involvement of poly(A) sequences Cell. 36: 1017-1025. DOI: 10.1016/0092-8674(84)90051-5  0.622
1983 Casey L, Palatnik CM, Jacobson A. Messenger RNA half-life in Dictyostelium discoideum. Developmental Biology. 95: 239-43. PMID 6825928 DOI: 10.1016/0012-1606(83)90023-4  0.504
1983 Jacobson A, Favreau M. Possible involvement of poly(A) in protein synthesis. Nucleic Acids Research. 11: 6353-68. PMID 6137807 DOI: 10.1093/NAR/11.18.6353  0.523
1981 Palatnik CM, Storti RV, Jacobson A. Partial purification of a developmentally regulated messenger RNA from Dictyostelium discoideum by thermal elution from poly(U)-sepharose. Journal of Molecular Biology. 150: 389-98. PMID 7299821 DOI: 10.1016/0022-2836(81)90554-4  0.616
1980 Palatnik CM, Storti RV, Capone AK, Jacobson A. Messenger RNA stability in Dictyostelium discoideum: does poly(A) have a regulatory role? Journal of Molecular Biology. 141: 99-118. PMID 7441754 DOI: 10.1016/0022-2836(80)90379-4  0.604
1980 Batts-Young B, Lodish HF, Jacobson A. Similarity of the primary sequences of ribosomal RNAs isolated from vegetative and developing cells of Dictyostelium discoidem. Developmental Biology. 78: 352-64. PMID 6773836 DOI: 10.1016/0012-1606(80)90340-1  0.501
1979 Palatnik CM, Storti RV, Jacobson A. Fractionation and functional analysis of newly synthesized and decaying messenger RNAs from vegetative cells of Dictyostelium discoideum. Journal of Molecular Biology. 128: 371-95. PMID 439140 DOI: 10.1016/0022-2836(79)90093-7  0.552
1976 Jacobson A, Lodish HF. Genetic control of development of the cellular slime mold, Dictyostelium discoideum. Annual Review of Genetics. 9: 145-85. PMID 174486 DOI: 10.1146/Annurev.Ge.09.120175.001045  0.545
1974 Lodish HF, Jacobson A, Firtel R, Alton T, Tuchman J. Synthesis of messenger RNA and chromosome structure in the cellular slime mold. Proceedings of the National Academy of Sciences of the United States of America. 71: 5103-8. PMID 4531041 DOI: 10.1073/Pnas.71.12.5103  0.625
1974 Jacobson A, Firtel RA, Lodish H. Transcription of polydeoxythymidylate sequences in the genome of the cellular slime mold, Dictyostelium discoideum. Proceedings of the National Academy of Sciences of the United States of America. 71: 1607-11. PMID 4525281 DOI: 10.1073/Pnas.71.5.1607  0.667
1974 Lodish HF, Firtel RA, Jacobson A. Transcription and structure of the genome of the cellular slime mold Dictyostelium discoideum. Cold Spring Harbor Symposia On Quantitative Biology. 38: 899-914. PMID 4524794 DOI: 10.1101/Sqb.1974.038.01.092  0.594
1973 Jacobson A, Housman D, Prensky W. Oligonucleotide fingerprinting of Hela cell 5 S RNA labeled in vitro with (125)I. Molecular Biology Reports. 1: 209-213. PMID 24197568 DOI: 10.1007/Bf00357643  0.449
1972 Jacobson A, Gillespie D. Genetic complementation between Escherichia coli RNA polymerase mutants. Biochemical and Biophysical Research Communications. 44: 1030-40. PMID 4946184 DOI: 10.1016/S0006-291X(71)80189-4  0.498
1970 Jacobson A, Gillespie D. An RNA Polymerase Mutant Defective in ATP Initiations Cold Spring Harbor Symposia On Quantitative Biology. 35: 85-93. DOI: 10.1101/Sqb.1970.035.01.014  0.555
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