| Year |
Citation |
Score |
| 2022 |
Liu R, Marshall K, Ma R, Lien Thi Pham K, Shetye G, Liu Z, Cho S, Jeong H, Franzblau SG, Moraski GC, Miller MJ. Syntheses and studies of deuterated Imdiazo[1,2-a]pyridine-3-carboxamides with potent anti-tuberculosis activity and improved metabolic properties. Bioorganic Chemistry. 128: 106074. PMID 35987188 DOI: 10.1016/j.bioorg.2022.106074 |
0.757 |
|
| 2021 |
Hopfner SM, Lee BS, Kalia NP, Miller MJ, Pethe K, Moraski GC. Syntheses and Structure-Activity Relationships of -Phenethyl-Quinazolin-4-yl-Amines as Potent Inhibitors of Cytochrome Oxidase in . Applied Sciences (Basel, Switzerland). 11. PMID 36698770 DOI: 10.3390/app11199092 |
0.761 |
|
| 2021 |
Sorayah R, Moraski GC, Barkan D, Pethe K. The QcrB Inhibitors TB47 and Telacebec Do Not Potentiate the Activity of Clofazimine in Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy. 65: e0096421. PMID 34543090 DOI: 10.1128/AAC.00964-21 |
0.373 |
|
| 2021 |
Hopfner SM, Lee BS, Kalia NP, Miller MJ, Pethe K, Moraski GC. Structure guided generation of thieno[3,2-]pyrimidin-4-amine oxidase inhibitors. Rsc Medicinal Chemistry. 12: 73-77. PMID 34046599 DOI: 10.1039/d0md00398k |
0.753 |
|
| 2021 |
Liu R, Markley L, Miller PA, Franzblau S, Shetye G, Ma R, Savková K, Mikušová K, Lee BS, Pethe K, Moraski GC, Miller MJ. Hydride-induced Meisenheimer complex formation reflects activity of nitro aromatic anti-tuberculosis compounds. Rsc Medicinal Chemistry. 12: 62-72. PMID 34046598 DOI: 10.1039/d0md00390e |
0.591 |
|
| 2020 |
Lee BS, Hards K, Engelhart CA, Hasenoehrl EJ, Kalia NP, Mackenzie JS, Sviriaeva E, Chong SMS, Manimekalai MSS, Koh VH, Chan J, Xu J, Alonso S, Miller MJ, Steyn AJC, ... ... Moraski GC, et al. Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis. Embo Molecular Medicine. e13207. PMID 33283973 DOI: 10.15252/emmm.202013207 |
0.552 |
|
| 2020 |
Moraski GC, Deboosère N, Marshall KL, Weaver HA, Vandeputte A, Hastings C, Woolhiser L, Lenaerts AJ, Brodin P, Miller MJ. Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds. Plos One. 15: e0227224. PMID 31905374 DOI: 10.1371/Journal.Pone.0227224 |
0.767 |
|
| 2019 |
Kalia NP, Shi Lee B, Ab Rahman NB, Moraski GC, Miller MJ, Pethe K. Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc:aa in Mycobacterium tuberculosis. Scientific Reports. 9: 8608. PMID 31197236 DOI: 10.1038/S41598-019-44887-9 |
0.524 |
|
| 2018 |
Scherr N, Bieri R, Thomas SS, Chauffour A, Kalia NP, Schneide P, Ruf MT, Lamelas A, Manimekalai MSS, Grüber G, Ishii N, Suzuki K, Tanner M, Moraski GC, Miller MJ, et al. Targeting the Mycobacterium ulcerans cytochrome bc:aa for the treatment of Buruli ulcer. Nature Communications. 9: 5370. PMID 30560872 DOI: 10.1038/S41467-018-07804-8 |
0.541 |
|
| 2018 |
O'Malley T, Alling T, Early JV, Wescott HA, Kumar A, Moraski GC, Miller MJ, Masquelin T, Hipskind PA, Parish T. Imidazopyridine compounds inhibit mycobacterial growth by depleting ATP levels. Antimicrobial Agents and Chemotherapy. PMID 29632008 DOI: 10.1128/Aac.02439-17 |
0.644 |
|
| 2017 |
Moraski GC, Bristol R, Seeger N, Boshoff HI, Tsang PS, Miller MJ. Preparation and Evaluation of Potent Pentafluorosulfanyl-Substituted Anti-Tuberculosis Compounds. Chemmedchem. PMID 28654200 DOI: 10.1002/Cmdc.201700170 |
0.678 |
|
| 2017 |
Moraski GC, Bristol R, Seeger N, Boshoff HI, Tsang PS, Miller MJ. Cover Picture: Preparation and Evaluation of Potent Pentafluorosulfanyl-Substituted Anti-Tuberculosis Compounds (ChemMedChem 14/2017) Chemmedchem. 12: 1102-1102. DOI: 10.1002/Cmdc.201700398 |
0.615 |
|
| 2016 |
Moraski GC, Seeger N, Miller PA, Oliver AG, Boshoff HI, Cho S, Mulugeta S, Anderson JR, Franzblau SG, Miller MJ. Arrival of Imidazo[2,1-b]thiazole-5-carboxamides: Potent Anti-tuberculosis Agents That Target QcrB. Acs Infectious Diseases. 2: 393-398. PMID 27627627 DOI: 10.1021/Acsinfecdis.5B00154 |
0.682 |
|
| 2016 |
Moraski GC, Cheng Y, Cho S, Cramer JW, Godfrey A, Masquelin T, Franzblau SG, Miller MJ, Schorey J. Imidazo[1,2-a]pyridine-3-carboxamides are Active Antimicrobial Agents of Mycobacterium avium Infection In Vivo. Antimicrobial Agents and Chemotherapy. PMID 27216051 DOI: 10.1128/Aac.00618-16 |
0.538 |
|
| 2015 |
Moraski GC, Miller PA, Bailey MA, Ollinger J, Parish T, Boshoff HI, Cho S, Anderson JR, Mulugeta S, Franzblau SG, Miller MJ. Putting Tuberculosis (TB) To Rest: Transformation of the Sleep Aid, Ambien, and "Anagrams" Generated Potent Antituberculosis Agents. Acs Infectious Diseases. 1: 85-90. PMID 25984566 DOI: 10.1021/Id500008T |
0.627 |
|
| 2014 |
Moraski GC, Oliver AG, Markley LD, Cho S, Franzblau SG, Miller MJ. Scaffold-switching: an exploration of 5,6-fused bicyclic heteroaromatics systems to afford antituberculosis activity akin to the imidazo[1,2-a]pyridine-3-carboxylates. Bioorganic & Medicinal Chemistry Letters. 24: 3493-8. PMID 24909079 DOI: 10.1016/J.Bmcl.2014.05.062 |
0.682 |
|
| 2014 |
Cheng Y, Moraski GC, Cramer J, Miller MJ, Schorey JS. Bactericidal activity of an imidazo[1, 2-a]pyridine using a mouse M. tuberculosis infection model. Plos One. 9: e87483. PMID 24498115 DOI: 10.1371/Journal.Pone.0087483 |
0.648 |
|
| 2013 |
Moraski GC, Markley LD, Cramer J, Hipskind PA, Boshoff H, Bailey M, Alling T, Ollinger J, Parish T, Miller MJ. Advancement of Imidazo[1,2-a]pyridines with Improved Pharmacokinetics and Nanomolar Activity Against Mycobacterium tuberculosis. Acs Medicinal Chemistry Letters. 4: 675-679. PMID 23930153 DOI: 10.1021/Ml400088Y |
0.712 |
|
| 2013 |
Ollinger J, Bailey MA, Moraski GC, Casey A, Florio S, Alling T, Miller MJ, Parish T. A dual read-out assay to evaluate the potency of compounds active against Mycobacterium tuberculosis. Plos One. 8: e60531. PMID 23593234 DOI: 10.1371/Journal.Pone.0060531 |
0.623 |
|
| 2013 |
Tiwari R, Moraski GC, Krch?ák V, Miller PA, Colon-Martinez M, Herrero E, Oliver AG, Miller MJ. Thiolates chemically induce redox activation of BTZ043 and related potent nitroaromatic anti-tuberculosis agents. Journal of the American Chemical Society. 135: 3539-49. PMID 23402278 DOI: 10.1021/Ja311058Q |
0.688 |
|
| 2012 |
Silveira GP, Ferreira M, Fernandes L, Moraski GC, Cho S, Hwang C, Franzblau SG, Sá MM. Allylic thiocyanates as a new class of antitubercular agents. Bioorganic & Medicinal Chemistry Letters. 22: 6486-9. PMID 22967767 DOI: 10.1016/J.Bmcl.2012.08.048 |
0.542 |
|
| 2012 |
Ji C, Lin W, Moraski GC, Thanassi JA, Pucci MJ, Franzblau SG, Möllmann U, Miller MJ. Syntheses and biological studies of novel spiropiperazinyl oxazolidinone antibacterial agents using a spirocyclic diene derived acylnitroso Diels-Alder reaction. Bioorganic & Medicinal Chemistry. 20: 3422-8. PMID 22560837 DOI: 10.1016/J.Bmc.2012.04.026 |
0.58 |
|
| 2012 |
Moraski GC, Markley LD, Chang M, Cho S, Franzblau SG, Hwang CH, Boshoff H, Miller MJ. Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds. Bioorganic & Medicinal Chemistry. 20: 2214-20. PMID 22391032 DOI: 10.1016/J.Bmc.2012.02.025 |
0.678 |
|
| 2011 |
Moraski GC, Thanassi JA, Podos SD, Pucci MJ, Miller MJ. One-step syntheses of nitrofuranyl benzimidazoles that are active against multidrug-resistant bacteria. The Journal of Antibiotics. 64: 667-671. PMID 21811261 DOI: 10.1038/Ja.2011.67 |
0.556 |
|
| 2011 |
Moraski GC, Markley LD, Hipskind PA, Boshoff H, Cho S, Franzblau SG, Miller MJ. Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity. Acs Medicinal Chemistry Letters. 2: 466-470. PMID 21691438 DOI: 10.1021/Ml200036R |
0.693 |
|
| 2011 |
Miller MJ, Walz AJ, Zhu H, Wu C, Moraski G, Möllmann U, Tristani EM, Crumbliss AL, Ferdig MT, Checkley L, Edwards RL, Boshoff HI. Design, synthesis, and study of a mycobactin-artemisinin conjugate that has selective and potent activity against tuberculosis and malaria. Journal of the American Chemical Society. 133: 2076-9. PMID 21275374 DOI: 10.1021/Ja109665T |
0.604 |
|
| 2010 |
Moraski GC, Franzblau SG, Miller MJ. UTILIZTION OF THE SUZUKI COUPLING TO ENHANCE THE ANTITUBERCULOSIS ACTIVITY OF ARYL OXAZOLES. Heterocycles. 80: 977-988. PMID 22003265 DOI: 10.3987/Com-09-S(S)69 |
0.563 |
|
| 2010 |
Stefely JA, Palchaudhuri R, Miller PA, Peterson RJ, Moraski GC, Hergenrother PJ, Miller MJ. N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a new scaffold that provides rapid access to antimicrotubule agents: synthesis and evaluation of antiproliferative activity against select cancer cell lines. Journal of Medicinal Chemistry. 53: 3389-95. PMID 20334421 DOI: 10.1021/Jm1000979 |
0.568 |
|
| 2010 |
Moraski GC, Chang M, Villegas-Estrada A, Franzblau SG, Möllmann U, Miller MJ. Structure-activity relationship of new anti-tuberculosis agents derived from oxazoline and oxazole benzyl esters. European Journal of Medicinal Chemistry. 45: 1703-16. PMID 20116900 DOI: 10.1016/J.Ejmech.2009.12.074 |
0.69 |
|
| 2009 |
Young DC, Kasmar A, Moraski G, Cheng TY, Walz AJ, Hu J, Xu Y, Endres GW, Uzieblo A, Zajonc D, Costello CE, Miller MJ, Moody DB. Synthesis of dideoxymycobactin antigens presented by CD1a reveals T cell fine specificity for natural lipopeptide structures. The Journal of Biological Chemistry. 284: 25087-96. PMID 19605355 DOI: 10.1074/Jbc.M109.000802 |
0.481 |
|
| 2009 |
Miller MJ, Zhu H, Xu Y, Wu C, Walz AJ, Vergne A, Roosenberg JM, Moraski G, Minnick AA, McKee-Dolence J, Hu J, Fennell K, Kurt Dolence E, Dong L, Franzblau S, et al. Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 22: 61-75. PMID 19130268 DOI: 10.1007/S10534-008-9185-0 |
0.525 |
|
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