☰

Payam A. Gammage - Publications

Affiliations: 
2010-2019 MRC Mitochondrial Biology Unit University of Cambridge, Cambridge, England, United Kingdom 
 2019- CRUK Beatson Institute University of Glasgow, Glasgow, Scotland, United Kingdom 
Area:
mitochondria, genome editing, metabolism
Tree Info Similar researchers PubMed Report error

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kim M, Gorelick AN, Vàzquez-García I, Williams MJ, Salehi S, Shi H, Weiner AC, Ceglia N, Funnell T, Park T, Boscenco S, O'Flanagan CH, Jiang H, Grewal D, Tang C, ... ... Gammage PA, et al. Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes. Nature Genetics. PMID 38741018 DOI: 10.1038/s41588-024-01724-8  0.55
2024 Mahmood M, Liu EM, Shergold AL, Tolla E, Tait-Mulder J, Huerta-Uribe A, Shokry E, Young AL, Lilla S, Kim M, Park T, Boscenco S, Manchon JL, Rodríguez-Antona C, Walters RC, ... ... Gammage PA, et al. Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Nature Cancer. PMID 38286828 DOI: 10.1038/s43018-023-00721-w  0.812
2023 Mahmood M, Liu EM, Shergold AL, Tolla E, Tait-Mulder J, Uribe AH, Shokry E, Young AL, Lilla S, Kim M, Park T, Manchon JL, Rodríguez-Antona C, Walters RC, Springett RJ, ... ... Gammage PA, et al. Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade. Biorxiv : the Preprint Server For Biology. PMID 36993533 DOI: 10.1101/2023.03.21.533091  0.822
2023 Shaw AM, Gammage PA. Coupling Differential Centrifugation with Exonuclease Treatment and Size Exclusion Chromatography (DIFSEC) for Purification of mtDNA from Mammalian Cells. Methods in Molecular Biology (Clifton, N.J.). 2615: 31-40. PMID 36807782 DOI: 10.1007/978-1-0716-2922-2_3  0.582
2022 Kim M, Mahmood M, Reznik E, Gammage PA. Mitochondrial DNA is a major source of driver mutations in cancer. Trends in Cancer. PMID 36041967 DOI: 10.1016/j.trecan.2022.08.001  0.842
2021 Gorelick AN, Kim M, Chatila WK, La K, Hakimi AA, Berger MF, Taylor BS, Gammage PA, Reznik E. Respiratory complex and tissue lineage drive recurrent mutations in tumour mtDNA. Nature Metabolism. PMID 33833465 DOI: 10.1038/s42255-021-00378-8  0.579
2020 Jackson CB, Turnbull DM, Minczuk M, Gammage PA. Therapeutic Manipulation of mtDNA Heteroplasmy: A Shifting Perspective. Trends in Molecular Medicine. 26: 698-709. PMID 32589937 DOI: 10.1016/J.Molmed.2020.02.006  0.855
2020 Bacman SR, Gammage PA, Minczuk M, Moraes CT. Manipulation of mitochondrial genes and mtDNA heteroplasmy. Methods in Cell Biology. 155: 441-487. PMID 32183972 DOI: 10.1016/Bs.Mcb.2019.12.004  0.848
2019 Andreazza S, Samstag CL, Sanchez-Martinez A, Fernandez-Vizarra E, Gomez-Duran A, Lee JJ, Tufi R, Hipp MJ, Schmidt EK, Nicholls TJ, Gammage PA, Chinnery PF, Minczuk M, Pallanck LJ, Kennedy SR, et al. Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila. Nature Communications. 10: 3280. PMID 31337756 DOI: 10.1038/S41467-019-10857-Y  0.838
2019 Gammage PA, Frezza C. Mitochondrial DNA: the overlooked oncogenome? Bmc Biology. 17: 53. PMID 31286943 DOI: 10.1186/S12915-019-0668-Y  0.722
2019 Hoitzing H, Gammage PA, Haute LV, Minczuk M, Johnston IG, Jones NS. Energetic costs of cellular and therapeutic control of stochastic mitochondrial DNA populations. Plos Computational Biology. 15: e1007023. PMID 31242175 DOI: 10.1371/Journal.Pcbi.1007023  0.779
2018 Gammage PA, Viscomi C, Simard ML, Costa ASH, Gaude E, Powell CA, Van Haute L, McCann BJ, Rebelo-Guiomar P, Cerutti R, Zhang L, Rebar EJ, Zeviani M, Frezza C, Stewart JB, et al. Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo. Nature Medicine. PMID 30250142 DOI: 10.1038/S41591-018-0165-9  0.848
2018 McCann BJ, Cox A, Gammage PA, Stewart JB, Zernicka-Goetz M, Minczuk M. Delivery of mtZFNs into Early Mouse Embryos. Methods in Molecular Biology (Clifton, N.J.). 1867: 215-228. PMID 30155826 DOI: 10.1007/978-1-4939-8799-3_16  0.848
2018 Gammage PA, Minczuk M. Enhanced Manipulation of Human Mitochondrial DNA Heteroplasmy In Vitro Using Tunable mtZFN Technology. Methods in Molecular Biology (Clifton, N.J.). 1867: 43-56. PMID 30155814 DOI: 10.1007/978-1-4939-8799-3_4  0.84
2018 Peeva V, Blei D, Trombly G, Corsi S, Szukszto MJ, Rebelo-Guiomar P, Gammage PA, Kudin AP, Becker C, Altmüller J, Minczuk M, Zsurka G, Kunz WS. Linear mitochondrial DNA is rapidly degraded by components of the replication machinery. Nature Communications. 9: 1727. PMID 29712893 DOI: 10.1038/S41467-018-04131-W  0.841
2018 Gaude E, Schmidt C, Gammage PA, Dugourd A, Blacker T, Chew SP, Saez-Rodriguez J, O'Neill JS, Szabadkai G, Minczuk M, Frezza C. NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction. Molecular Cell. 69: 581-593.e7. PMID 29452638 DOI: 10.1016/J.Molcel.2018.01.034  0.849
2017 Kullar PJ, Gomez-Duran A, Gammage PA, Garone C, Minczuk M, Golder Z, Wilson J, Montoya J, Häkli S, Kärppä M, Horvath R, Majamaa K, Chinnery PF. Heterozygous SSBP1 start loss mutation co-segregates with hearing loss and the m.1555A>G mtDNA variant in a large multigenerational family. Brain : a Journal of Neurology. PMID 29182774 DOI: 10.1093/Brain/Awx295  0.766
2017 Gammage PA, Moraes CT, Minczuk M. Mitochondrial Genome Engineering: The Revolution May Not Be CRISPR-Ized. Trends in Genetics : Tig. PMID 29179920 DOI: 10.1016/J.Tig.2017.11.001  0.843
2016 Gammage PA, Gaude E, Van Haute L, Rebelo-Guiomar P, Jackson CB, Rorbach J, Pekalski ML, Robinson AJ, Charpentier M, Concordet JP, Frezza C, Minczuk M. Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs. Nucleic Acids Research. PMID 27466392 DOI: 10.1093/Nar/Gkw676  0.841
2016 Gammage PA, Van Haute L, Minczuk M. Engineered mtZFNs for Manipulation of Human Mitochondrial DNA Heteroplasmy. Methods in Molecular Biology (Clifton, N.J.). 1351: 145-62. PMID 26530680 DOI: 10.1007/978-1-4939-3040-1_11  0.817
2016 Rorbach J, Gammage PA, Minczuk M. C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome. Nucleic Acids Research. 44: 992. PMID 26487634 DOI: 10.1093/Nar/Gkv1125  0.838
2014 Rorbach J, Boesch P, Gammage PA, Nicholls TJ, Pearce SF, Patel D, Hauser A, Perocchi F, Minczuk M. MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome. Molecular Biology of the Cell. 25: 2542-55. PMID 25009282 DOI: 10.1091/Mbc.E14-01-0014  0.833
2014 Gammage PA, Rorbach J, Vincent AI, Rebar EJ, Minczuk M. Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations. Embo Molecular Medicine. 6: 458-66. PMID 24567072 DOI: 10.1002/Emmm.201303672  0.857
2013 Kazak L, Reyes A, Duncan AL, Rorbach J, Wood SR, Brea-Calvo G, Gammage PA, Robinson AJ, Minczuk M, Holt IJ. Alternative translation initiation augments the human mitochondrial proteome. Nucleic Acids Research. 41: 2354-69. PMID 23275553 DOI: 10.1093/Nar/Gks1347  0.836
2012 Rorbach J, Gammage PA, Minczuk M. C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome. Nucleic Acids Research. 40: 4097-109. PMID 22238376 DOI: 10.1093/nar/gkr1282  0.833
Show low-probability matches.