Year |
Citation |
Score |
2020 |
Kazak L, Cohen P. Creatine metabolism: energy homeostasis, immunity and cancer biology. Nature Reviews. Endocrinology. PMID 32493980 DOI: 10.1038/s41574-020-0365-5 |
0.96 |
|
2020 |
Jedrychowski MP, Lu GZ, Szpyt J, Mariotti M, Garrity R, Paulo JA, Schweppe DK, Laznik-Bogoslavski D, Kazak L, Murphy MP, Gladyshev VN, Gygi SP, Chouchani ET, Spiegelman BM. Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32358195 DOI: 10.1073/pnas.2001387117 |
0.56 |
|
2019 |
Bertholet AM, Chouchani ET, Kazak L, Angelin A, Fedorenko A, Long JZ, Vidoni S, Garrity R, Cho J, Terada N, Wallace DC, Spiegelman BM, Kirichok Y. H transport is an integral function of the mitochondrial ADP/ATP carrier. Nature. 571: 515-520. PMID 31341297 DOI: 10.1038/s41586-019-1400-3 |
0.56 |
|
2019 |
Kazak L, Rahbani JF, Samborska B, Lu GZ, Jedrychowski MP, Lajoie M, Zhang S, Ramsay LC, Dou FY, Tenen D, Chouchani ET, Dzeja P, Watson IR, Tsai L, Rosen ED, et al. Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity. Nature Metabolism. 1: 360-370. PMID 31161155 DOI: 10.1038/s42255-019-0035-x |
0.56 |
|
2019 |
Dumesic PA, Egan DF, Gut P, Tran MT, Parisi A, Chatterjee N, Jedrychowski M, Paschini M, Kazak L, Wilensky SE, Dou F, Bogoslavski D, Cartier JA, Perrimon N, Kajimura S, et al. An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna. Cell Metabolism. PMID 31105043 DOI: 10.1016/j.cmet.2019.04.013 |
0.56 |
|
2018 |
Chouchani ET, Kazak L, Spiegelman BM. New Advances in Adaptive Thermogenesis: UCP1 and Beyond. Cell Metabolism. PMID 30503034 DOI: 10.1016/j.cmet.2018.11.002 |
0.56 |
|
2018 |
Cluett TJ, Akman G, Reyes A, Kazak L, Mitchell A, Wood SR, Spinazzola A, Spelbrink JN, Holt IJ. Transcript availability dictates the balance between strand-asynchronous and strand-coupled mitochondrial DNA replication. Nucleic Acids Research. PMID 30239839 DOI: 10.1093/nar/gky852 |
0.4 |
|
2018 |
Kong X, Yao T, Zhou P, Kazak L, Tenen D, Lyubetskaya A, Dawes BA, Tsai L, Kahn BB, Spiegelman BM, Liu T, Rosen ED. Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin. Cell Metabolism. PMID 30078553 DOI: 10.1016/j.cmet.2018.07.004 |
0.56 |
|
2018 |
Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, et al. Accumulation of succinate controls activation of adipose tissue thermogenesis. Nature. PMID 30022159 DOI: 10.1038/s41586-018-0353-2 |
0.56 |
|
2018 |
Paulo JA, Jedrychowski MP, Chouchani ET, Kazak L, Gygi SP. Multiplexed isobaric tag-based profiling of seven murine tissues following in vivo nicotine treatment using a minimalistic proteomics strategy. Proteomics. e1700326. PMID 29660237 DOI: 10.1002/pmic.201700326 |
0.56 |
|
2018 |
Khandekar MJ, Banks AS, Laznik-Bogoslavski D, White JP, Choi JH, Kazak L, Lo JC, Cohen P, Wong KK, Kamenecka TM, Griffin PR, Spiegelman BM. Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29295932 DOI: 10.1073/pnas.1717776115 |
0.96 |
|
2017 |
Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM. Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Cell Metabolism. PMID 28844881 DOI: 10.1016/j.cmet.2017.08.009 |
0.56 |
|
2017 |
Chouchani ET, Kazak L, Spiegelman BM. Mitochondrial reactive oxygen species and adipose tissue thermogenesis: bridging physiology and mechanisms. The Journal of Biological Chemistry. PMID 28842500 DOI: 10.1074/jbc.R117.789628 |
0.56 |
|
2017 |
Kazak L, Chouchani ET, Stavrovskaya IG, Lu GZ, Jedrychowski MP, Egan DF, Kumari M, Kong X, Erickson BK, Szpyt J, Rosen ED, Murphy MP, Kristal BS, Gygi SP, Spiegelman BM. UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630339 DOI: 10.1073/pnas.1705406114 |
0.56 |
|
2017 |
Bertholet AM, Kazak L, Chouchani ET, Bogaczyńska MG, Paranjpe I, Wainwright GL, Bétourné A, Kajimura S, Spiegelman BM, Kirichok Y. Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling. Cell Metabolism. 25: 811-822.e4. PMID 28380374 DOI: 10.1016/j.cmet.2017.03.002 |
0.56 |
|
2016 |
Liyanage SU, Coyaud E, Laurent EM, Hurren R, Maclean N, Wood SR, Kazak L, Shamas-Din A, Holt I, Raught B, Schimmer A. Characterizing the mitochondrial DNA polymerase gamma interactome by BioID identifies Ruvbl2 localizes to the mitochondria. Mitochondrion. PMID 27845271 DOI: 10.1016/j.mito.2016.11.001 |
0.4 |
|
2016 |
Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED. IRF3 promotes adipose inflammation and insulin resistance and represses browning. The Journal of Clinical Investigation. PMID 27400129 DOI: 10.1172/JCI86080 |
0.4 |
|
2016 |
Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM. Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature. PMID 27281219 DOI: 10.1038/nature18279 |
0.56 |
|
2016 |
Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM. Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature. PMID 27027295 DOI: 10.1038/nature17399 |
0.4 |
|
2016 |
Holt IJ, Kazak L, Reyes A, Wood SR. Analysis of Replicating Mitochondrial DNA by In Organello Labeling and Two-Dimensional Agarose Gel Electrophoresis. Methods in Molecular Biology (Clifton, N.J.). 1351: 95-113. PMID 26530677 DOI: 10.1007/978-1-4939-3040-1_8 |
0.4 |
|
2015 |
Kazak L, Chouchani ET, Jedrychowski MP, Erickson BK, Shinoda K, Cohen P, Vetrivelan R, Lu GZ, Laznik-Bogoslavski D, Hasenfuss SC, Kajimura S, Gygi SP, Spiegelman BM. A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat. Cell. 163: 643-55. PMID 26496606 DOI: 10.1016/j.cell.2015.09.035 |
0.4 |
|
2014 |
Kir S, White JP, Kleiner S, Kazak L, Cohen P, Baracos VE, Spiegelman BM. Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia. Nature. 513: 100-4. PMID 25043053 DOI: 10.1038/nature13528 |
0.4 |
|
2014 |
Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, et al. IRF4 is a key thermogenic transcriptional partner of PGC-1α. Cell. 158: 69-83. PMID 24995979 DOI: 10.1016/j.cell.2014.04.049 |
0.4 |
|
2013 |
Ye L, Wu J, Cohen P, Kazak L, Khandekar MJ, Jedrychowski MP, Zeng X, Gygi SP, Spiegelman BM. Fat cells directly sense temperature to activate thermogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 12480-5. PMID 23818608 DOI: 10.1073/pnas.1310261110 |
0.4 |
|
2013 |
Kazak L, Reyes A, He J, Wood SR, Brea-Calvo G, Holen TT, Holt IJ. A cryptic targeting signal creates a mitochondrial FEN1 isoform with tailed R-Loop binding properties. Plos One. 8: e62340. PMID 23675412 DOI: 10.1371/journal.pone.0062340 |
0.4 |
|
2013 |
Reyes A, Kazak L, Wood SR, Yasukawa T, Jacobs HT, Holt IJ. Mitochondrial DNA replication proceeds via a 'bootlace' mechanism involving the incorporation of processed transcripts. Nucleic Acids Research. 41: 5837-50. PMID 23595151 DOI: 10.1093/nar/gkt196 |
0.4 |
|
2013 |
Kazak L, Reyes A, Duncan AL, Rorbach J, Wood SR, Brea-Calvo G, Gammage PA, Robinson AJ, Minczuk M, Holt IJ. Alternative translation initiation augments the human mitochondrial proteome. Nucleic Acids Research. 41: 2354-69. PMID 23275553 DOI: 10.1093/nar/gks1347 |
0.4 |
|
2012 |
Kazak L, Reyes A, Holt IJ. Minimizing the damage: repair pathways keep mitochondrial DNA intact. Nature Reviews. Molecular Cell Biology. 13: 659-71. PMID 22992591 DOI: 10.1038/nrm3439 |
0.4 |
|
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