Shingo Kajimura - Publications

Affiliations: 
Biochemistry and Molecular Biology University of California, San Francisco, San Francisco, CA 
Area:
Molecular Biology, Biochemistry, Cell Biology

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Oguri Y, Shinoda K, Kim H, Alba DL, Bolus WR, Wang Q, Brown Z, Pradhan RN, Tajima K, Yoneshiro T, Ikeda K, Chen Y, Cheang RT, Tsujino K, Kim CR, ... ... Kajimura S, et al. CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. Cell. PMID 32615086 DOI: 10.1016/j.cell.2020.06.021  0.88
2020 Kajimura S, Spiegelman BM. Confounding issues in the "humanized" BAT of mice. Nature Metabolism. 2: 303-304. PMID 32405619 DOI: 10.1038/s42255-020-0192-y  0.88
2019 Chouchani ET, Kajimura S. Metabolic adaptation and maladaptation in adipose tissue. Nature Metabolism. 1: 189-200. PMID 31903450 DOI: 10.1038/s42255-018-0021-8  0.48
2019 Dumesic PA, Egan DF, Gut P, Tran MT, Parisi A, Chatterjee N, Jedrychowski M, Paschini M, Kazak L, Wilensky SE, Dou F, Bogoslavski D, Cartier JA, Perrimon N, Kajimura S, et al. An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna. Cell Metabolism. PMID 31105043 DOI: 10.1016/j.cmet.2019.04.013  0.88
2018 Mills EL, Pierce KA, Jedrychowski MP, Garrity R, Winther S, Vidoni S, Yoneshiro T, Spinelli JB, Lu GZ, Kazak L, Banks AS, Haigis MC, Kajimura S, Murphy MP, Gygi SP, et al. Accumulation of succinate controls activation of adipose tissue thermogenesis. Nature. PMID 30022159 DOI: 10.1038/s41586-018-0353-2  0.48
2018 Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J, Cohen P, Koliwad SK, Kajimura S. Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis. Cell Metabolism. 27: 180-194.e6. PMID 29320702 DOI: 10.1016/j.cmet.2017.12.005  0.4
2017 Bertholet AM, Kazak L, Chouchani ET, Bogaczyńska MG, Paranjpe I, Wainwright GL, Bétourné A, Kajimura S, Spiegelman BM, Kirichok Y. Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling. Cell Metabolism. 25: 811-822.e4. PMID 28380374 DOI: 10.1016/j.cmet.2017.03.002  0.88
2017 Giordano A, Perugini J, Kristensen DM, Sartini L, Frontini A, Kajimura S, Kristiansen K, Cinti S. Mammary Alveolar Epithelial Cells Convert to Brown Adipocytes in Post-lactating Mice. Journal of Cellular Physiology. PMID 28191637 DOI: 10.1002/jcp.25858  0.4
2016 Chondronikola M, Volpi E, Børsheim E, Porter C, Saraf MK, Annamalai P, Yfanti C, Chao T, Wong D, Shinoda K, Labbė SM, Hurren NM, Cesani F, Kajimura S, Sidossis LS. Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans. Cell Metabolism. PMID 27238638 DOI: 10.1016/j.cmet.2016.04.029  0.56
2016 Svensson KJ, Long JZ, Jedrychowski MP, Cohen P, Lo JC, Serag S, Kir S, Shinoda K, Tartaglia JA, Rao RR, Chédotal A, Kajimura S, Gygi SP, Spiegelman BM. A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function. Cell Metabolism. PMID 26876562 DOI: 10.1016/j.cmet.2016.01.008  0.88
2015 Shinoda K, Ohyama K, Hasegawa Y, Chang HY, Ogura M, Sato A, Hong H, Hosono T, Sharp LZ, Scheel DW, Graham M, Ishihama Y, Kajimura S. Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure. Cell Metabolism. PMID 26525534 DOI: 10.1016/j.cmet.2015.09.029  0.56
2015 Kazak L, Chouchani ET, Jedrychowski MP, Erickson BK, Shinoda K, Cohen P, Vetrivelan R, Lu GZ, Laznik-Bogoslavski D, Hasenfuss SC, Kajimura S, Gygi SP, Spiegelman BM. A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat. Cell. 163: 643-55. PMID 26496606 DOI: 10.1016/j.cell.2015.09.035  0.88
2015 Güller I, McNaughton S, Crowley T, Gilsanz V, Kajimura S, Watt M, Russell AP. Comparative analysis of microRNA expression in mouse and human brown adipose tissue. Bmc Genomics. 16: 820. PMID 26482036 DOI: 10.1186/s12864-015-2045-8  0.56
2015 Kajimura S, Spiegelman BM, Seale P. Brown and Beige Fat: Physiological Roles beyond Heat Generation. Cell Metabolism. 22: 546-59. PMID 26445512 DOI: 10.1016/j.cmet.2015.09.007  0.56
2015 Abe Y, Rozqie R, Matsumura Y, Kawamura T, Nakaki R, Tsurutani Y, Tanimura-Inagaki K, Shiono A, Magoori K, Nakamura K, Ogi S, Kajimura S, Kimura H, Tanaka T, Fukami K, et al. JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis. Nature Communications. 6: 7052. PMID 25948511 DOI: 10.1038/ncomms8052  0.56
2015 Oh CM, Namkung J, Go Y, Shong KE, Kim K, Kim H, Park BY, Lee HW, Jeon YH, Song J, Shong M, Yadav VK, Karsenty G, Kajimura S, Lee IK, et al. Regulation of systemic energy homeostasis by serotonin in adipose tissues. Nature Communications. 6: 6794. PMID 25864946 DOI: 10.1038/ncomms7794  0.56
2015 Shinoda K, Luijten IH, Hasegawa Y, Hong H, Sonne SB, Kim M, Xue R, Chondronikola M, Cypess AM, Tseng YH, Nedergaard J, Sidossis LS, Kajimura S. Genetic and functional characterization of clonally derived adult human brown adipocytes. Nature Medicine. 21: 389-94. PMID 25774848 DOI: 10.1038/nm.3819  0.56
2015 Sidossis L, Kajimura S. Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis. The Journal of Clinical Investigation. 125: 478-86. PMID 25642708 DOI: 10.1172/JCI78362  0.56
2015 Ohyama K, Nogusa Y, Suzuki K, Shinoda K, Kajimura S, Bannai M. A combination of exercise and capsinoid supplementation additively suppresses diet-induced obesity by increasing energy expenditure in mice. American Journal of Physiology. Endocrinology and Metabolism. 308: E315-23. PMID 25516550 DOI: 10.1152/ajpendo.00354.2014  0.56
2014 Galmozzi A, Sonne SB, Altshuler-Keylin S, Hasegawa Y, Shinoda K, Luijten IH, Chang JW, Sharp LZ, Cravatt BF, Saez E, Kajimura S. ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue. Cell Reports. 9: 1584-93. PMID 25466254 DOI: 10.1016/j.celrep.2014.10.066  0.56
2014 Gridley T, Kajimura S. Lightening up a notch: Notch regulation of energy metabolism. Nature Medicine. 20: 811-2. PMID 25100522 DOI: 10.1038/nm.3650  0.56
2014 Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, ... Kajimura S, et al. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell. 156: 304-16. PMID 24439384 DOI: 10.1016/j.cell.2013.12.021  0.56
2014 Kajimura S, Saito M. A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis. Annual Review of Physiology. 76: 225-49. PMID 24188710 DOI: 10.1146/annurev-physiol-021113-170252  0.56
2013 Ohno H, Shinoda K, Ohyama K, Sharp LZ, Kajimura S. EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex. Nature. 504: 163-7. PMID 24196706 DOI: 10.1038/nature12652  0.56
2013 Aune UL, Ruiz L, Kajimura S. Isolation and differentiation of stromal vascular cells to beige/brite cells. Journal of Visualized Experiments : Jove. PMID 23568137 DOI: 10.3791/50191  0.56
2013 Gilsanz V, Hu HH, Kajimura S. Relevance of brown adipose tissue in infancy and adolescence. Pediatric Research. 73: 3-9. PMID 23090604 DOI: 10.1038/pr.2012.141  0.56
2012 Kang S, Akerblad P, Kiviranta R, Gupta RK, Kajimura S, Griffin MJ, Min J, Baron R, Rosen ED. Regulation of early adipose commitment by Zfp521. Plos Biology. 10: e1001433. PMID 23209378 DOI: 10.1371/journal.pbio.1001433  0.56
2012 Sharp LZ, Shinoda K, Ohno H, Scheel DW, Tomoda E, Ruiz L, Hu H, Wang L, Pavlova Z, Gilsanz V, Kajimura S. Human BAT possesses molecular signatures that resemble beige/brite cells. Plos One. 7: e49452. PMID 23166672 DOI: 10.1371/journal.pone.0049452  0.56
2012 Koncarevic A, Kajimura S, Cornwall-Brady M, Andreucci A, Pullen A, Sako D, Kumar R, Grinberg AV, Liharska K, Ucran JA, Howard E, Spiegelman BM, Seehra J, Lachey J. A novel therapeutic approach to treating obesity through modulation of TGFβ signaling. Endocrinology. 153: 3133-46. PMID 22549226 DOI: 10.1210/en.2012-1016  0.56
2012 Ohno H, Shinoda K, Spiegelman BM, Kajimura S. PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein. Cell Metabolism. 15: 395-404. PMID 22405074 DOI: 10.1016/j.cmet.2012.01.019  0.56
2012 Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 481: 463-8. PMID 22237023 DOI: 10.1038/nature10777  0.56
2012 Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, et al. Boström et al. reply Nature. 488: E10-E11. DOI: 10.1038/nature11365  0.56
2011 Kamei H, Ding Y, Kajimura S, Wells M, Chiang P, Duan C. Role of IGF signaling in catch-up growth and accelerated temporal development in zebrafish embryos in response to oxygen availability. Development (Cambridge, England). 138: 777-86. PMID 21266413 DOI: 10.1242/dev.056853  0.56
2011 Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. The Journal of Clinical Investigation. 121: 96-105. PMID 21123942 DOI: 10.1172/JCI44271  0.56
2010 Choi JH, Banks AS, Estall JL, Kajimura S, Boström P, Laznik D, Ruas JL, Chalmers MJ, Kamenecka TM, Blüher M, Griffin PR, Spiegelman BM. Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Nature. 466: 451-6. PMID 20651683 DOI: 10.1038/nature09291  0.56
2010 Kajimura S, Seale P, Spiegelman BM. Transcriptional control of brown fat development. Cell Metabolism. 11: 257-62. PMID 20374957 DOI: 10.1016/j.cmet.2010.03.005  0.56
2009 Kajimura S, Seale P, Kubota K, Lunsford E, Frangioni JV, Gygi SP, Spiegelman BM. Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex. Nature. 460: 1154-8. PMID 19641492 DOI: 10.1038/nature08262  0.56
2009 Seale P, Kajimura S, Spiegelman BM. Transcriptional control of brown adipocyte development and physiological function--of mice and men. Genes & Development. 23: 788-97. PMID 19339685 DOI: 10.1101/gad.1779209  0.56
2008 Cooper MP, Uldry M, Kajimura S, Arany Z, Spiegelman BM. Modulation of PGC-1 coactivator pathways in brown fat differentiation through LRP130. The Journal of Biological Chemistry. 283: 31960-7. PMID 18728005 DOI: 10.1074/jbc.M805431200  0.56
2008 Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scimè A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM. PRDM16 controls a brown fat/skeletal muscle switch. Nature. 454: 961-7. PMID 18719582 DOI: 10.1038/nature07182  0.56
2008 Kajimura S, Seale P, Tomaru T, Erdjument-Bromage H, Cooper MP, Ruas JL, Chin S, Tempst P, Lazar MA, Spiegelman BM. Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes & Development. 22: 1397-409. PMID 18483224 DOI: 10.1101/gad.1666108  0.56
2007 Seale P, Kajimura S, Yang W, Chin S, Rohas LM, Uldry M, Tavernier G, Langin D, Spiegelman BM. Transcriptional control of brown fat determination by PRDM16. Cell Metabolism. 6: 38-54. PMID 17618855 DOI: 10.1016/j.cmet.2007.06.001  0.56
2007 Takahashi H, Prunet P, Kitahashi T, Kajimura S, Hirano T, Grau EG, Sakamoto T. Prolactin receptor and proliferating/apoptotic cells in esophagus of the Mozambique tilapia (Oreochromis mossambicus) in fresh water and in seawater. General and Comparative Endocrinology. 152: 326-31. PMID 17418192 DOI: 10.1016/j.ygcen.2007.02.021  0.56
2007 Kajimura S, Duan C. Insulin-like growth factor-binding protein-1: An evolutionarily conserved fine tuner of insulin-like growth factor action under catabolic and stressful conditions Journal of Fish Biology. 71: 309-325. DOI: 10.1111/j.1095-8649.2007.01606.x  0.56
2006 Kajimura S, Aida K, Duan C. Understanding hypoxia-induced gene expression in early development: in vitro and in vivo analysis of hypoxia-inducible factor 1-regulated zebra fish insulin-like growth factor binding protein 1 gene expression. Molecular and Cellular Biology. 26: 1142-55. PMID 16428465 DOI: 10.1128/MCB.26.3.1142-1155.2006  0.56
2005 Kajimura S, Seale AP, Hirano T, Cooke IM, Grau EG. Physiological concentrations of ouabain rapidly inhibit prolactin release from the tilapia pituitary. General and Comparative Endocrinology. 143: 240-50. PMID 15922343 DOI: 10.1016/j.ygcen.2005.04.002  0.56
2005 Kajimura S, Aida K, Duan C. Insulin-like growth factor-binding protein-1 (IGFBP-1) mediates hypoxia-induced embryonic growth and developmental retardation. Proceedings of the National Academy of Sciences of the United States of America. 102: 1240-5. PMID 15644436 DOI: 10.1073/pnas.0407443102  0.56
2004 Kajimura S, Kawaguchi N, Kaneko T, Kawazoe I, Hirano T, Visitacion N, Grau EG, Aida K. Identification of the growth hormone receptor in an advanced teleost, the tilapia (Oreochromis mossambicus) with special reference to its distinct expression pattern in the ovary Journal of Endocrinology. 181: 65-76. PMID 15072567 DOI: 10.1677/joe.0.1810065  0.56
2004 Uchida K, Yoshikawa-Ebesu JS, Kajimura S, Yada T, Hirano T, Gordon Grau E. In vitro effects of cortisol on the release and gene expression of prolactin and growth hormone in the tilapia, Oreochromis mossambicus. General and Comparative Endocrinology. 135: 116-25. PMID 14644651 DOI: 10.1016/j.ygcen.2003.08.010  0.56
2004 Kajimura S, Hirano T, Moriyama S, Vakkuri O, Leppäluoto J, Grau EG. Changes in plasma concentrations of immunoreactive ouabain in the tilapia in response to changing salinity: Is ouabain a hormone in fish? General and Comparative Endocrinology. 135: 90-99. PMID 14644648 DOI: 10.1016/j.ygcen.2003.08.006  0.56
2003 Kajimura S, Hirano T, Visitacion N, Moriyama S, Aida K, Grau EG. Dual mode of cortisol action on GH/IGF-I/IGF binding proteins in the tilapia, Oreochromis mossambicus Journal of Endocrinology. 178: 91-99. PMID 12844340 DOI: 10.1677/joe.0.1780091  0.56
2003 Uchida K, Kajimura S, Riley LG, Hirano T, Aida K, Grau EG. Effects of fasting on growth hormone/insulin-like growth factor I axis in the tilapia, Oreochromis mossambicus Comparative Biochemistry and Physiology - a Molecular and Integrative Physiology. 134: 429-439. PMID 12547273 DOI: 10.1016/S1095-6433(02)00318-5  0.56
2003 Kajimura S, Kawaguchi N, Kawazoe K, Okubo K, Aida K. Identification of growth hormone receptor in the ovary of tilapia, Oreochromis mossambicus Fish Physiology and Biochemistry. 28: 211-212. DOI: 10.1023/B:FISH.0000030531.88537.c9  0.56
2003 Ishii S, Yoshiura Y, Kajimura S, Mochioka N, Aida K. Gonadal development and expression profiles of gonadotropin genes in wild sea conger, Ariosoma meeki Fish Physiology and Biochemistry. 28: 95-96. DOI: 10.1023/B:FISH.0000030486.07523.84  0.56
2002 Seale AP, Riley LG, Leedom TA, Kajimura S, Dores RM, Hirano T, Grau EG. Effects of environmental osmolality on release of prolactin, growth hormone and ACTH from the tilapia pituitary. General and Comparative Endocrinology. 128: 91-101. PMID 12392682 DOI: 10.1016/S0016-6480(02)00027-8  0.56
2002 Kajimura S, Uchida K, Yada T, Hirano T, Aida K, Gordon Grau E. Effects of insulin-like growth factors (IGF-I and -II) on growth hormone and prolactin release and gene expression in euryhaline tilapia, Oreochromis mossambicus. General and Comparative Endocrinology. 127: 223-31. PMID 12225763 DOI: 10.1016/S0016-6480(02)00055-2  0.56
2002 Yada T, Uchida K, Kajimura S, Azuma T, Hirano T, Grau EG. Immunomodulatory effects of prolactin and growth hormone in the tilapia, Oreochromis mossambicus. The Journal of Endocrinology. 173: 483-92. PMID 12065238 DOI: 10.1677/joe.0.1730483  0.56
2002 Kajimura S, Uchida K, Yada T, Riley LG, Byatt JC, Collier RJ, Aida K, Hirano T, Grau EG. Stimulation of insulin-like growth factor-I production by recombinant bovine growth hormone in Mozambique tilapia, Oreochromis mossambicus Fish Physiology and Biochemistry. 25: 221-230. DOI: 10.1023/A:1022268811599  0.56
2002 Kajimura S. Impression of 70th Anniversary Symposium-1 Nippon Suisan Gakkaishi (Japanese Edition). 68: 259.  0.56
2001 Kajimura S, Yoshiura Y, Suzuki M, Aida K. cDNA cloning of two gonadotropin β subunits (GTH-Iβ and -IIβ) and their expression profiles during gametogenesis in the Japanese flounder (Paralichthys olivaceus) General and Comparative Endocrinology. 122: 117-129. PMID 11316417 DOI: 10.1006/gcen.2000.7610  0.56
2001 Kajimura S, Yoshiura Y, Suzuki M, Utoh T, Horie N, Oka H, Aida K. Changes in the levels of mRNA coding for gonadotropin Iβ and IIβ subunits during vitellogenesis in the common Japanese conger Conger myriaster Fisheries Science. 67: 1053-1062. DOI: 10.1046/j.1444-2906.2001.00361.x  0.56
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