Evan D. Rosen - Publications

Harvard University, Cambridge, MA, United States 
Molecular Biology, Endocrinology Biology, Physiology Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED. IRF3 promotes adipose inflammation and insulin resistance and represses browning. The Journal of Clinical Investigation. PMID 27400129 DOI: 10.1172/JCI86080  0.88
2016 Kang S, Tsai LT, Rosen ED. Nuclear Mechanisms of Insulin Resistance. Trends in Cell Biology. PMID 26822036 DOI: 10.1016/j.tcb.2016.01.002  0.88
2015 Herman MA, Rosen ED. Making Biological Sense of GWAS Data: Lessons from the FTO Locus. Cell Metabolism. 22: 538-9. PMID 26445508 DOI: 10.1016/j.cmet.2015.09.018  0.88
2015 Kang S, Tsai LT, Zhou Y, Evertts A, Xu S, Griffin MJ, Issner R, Whitton HJ, Garcia BA, Epstein CB, Mikkelsen TS, Rosen ED. Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis. Nature Cell Biology. 17: 44-56. PMID 25503565 DOI: 10.1038/ncb3080  0.88
2014 Majithia AR, Flannick J, Shahinian P, Guo M, Bray MA, Fontanillas P, Gabriel SB, Rosen ED, Altshuler D. Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 111: 13127-32. PMID 25157153 DOI: 10.1073/pnas.1410428111  0.88
2014 Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, ... Rosen ED, et al. IRF4 is a key thermogenic transcriptional partner of PGC-1α. Cell. 158: 69-83. PMID 24995979 DOI: 10.1016/j.cell.2014.04.049  0.88
2014 Long JZ, Svensson KJ, Tsai L, Zeng X, Roh HC, Kong X, Rao RR, Lou J, Lokurkar I, Baur W, Castellot JJ, Rosen ED, Spiegelman BM. A smooth muscle-like origin for beige adipocytes. Cell Metabolism. 19: 810-20. PMID 24709624 DOI: 10.1016/j.cmet.2014.03.025  0.88
2014 Kang S, Kong X, Rosen ED. Adipocyte-specific transgenic and knockout models. Methods in Enzymology. 537: 1-16. PMID 24480338 DOI: 10.1016/B978-0-12-411619-1.00001-X  0.88
2014 Rosen ED, Spiegelman BM. What we talk about when we talk about fat. Cell. 156: 20-44. PMID 24439368 DOI: 10.1016/j.cell.2013.12.012  0.88
2013 Griffin MJ, Zhou Y, Kang S, Zhang X, Mikkelsen TS, Rosen ED. Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes. The Journal of Biological Chemistry. 288: 35925-39. PMID 24174531 DOI: 10.1074/jbc.M113.491936  0.88
2013 Bozec A, Bakiri L, Jimenez M, Rosen ED, Catalá-Lehnen P, Schinke T, Schett G, Amling M, Wagner EF. Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism. Journal of Cell Science. 126: 5432-40. PMID 24046454 DOI: 10.1242/jcs.134510  0.88
2013 Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A. Charting a dynamic DNA methylation landscape of the human genome. Nature. 500: 477-81. PMID 23925113 DOI: 10.1038/nature12433  0.88
2013 Eguchi J, Kong X, Tenta M, Wang X, Kang S, Rosen ED. Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization. Diabetes. 62: 3394-403. PMID 23835343 DOI: 10.2337/db12-1327  0.88
2013 Kiviranta R, Yamana K, Saito H, Ho DK, Laine J, Tarkkonen K, Nieminen-Pihala V, Hesse E, Correa D, Määttä J, Tessarollo L, Rosen ED, Horne WC, Jenkins NA, Copeland NG, et al. Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages. The Journal of Experimental Medicine. 210: 969-85. PMID 23569325 DOI: 10.1084/jem.20121187  0.88
2013 Lee KY, Russell SJ, Ussar S, Boucher J, Vernochet C, Mori MA, Smyth G, Rourk M, Cederquist C, Rosen ED, Kahn BB, Kahn CR. Lessons on conditional gene targeting in mouse adipose tissue. Diabetes. 62: 864-74. PMID 23321074 DOI: 10.2337/db12-1089  0.88
2012 Kang S, Akerblad P, Kiviranta R, Gupta RK, Kajimura S, Griffin MJ, Min J, Baron R, Rosen ED. Regulation of early adipose commitment by Zfp521. Plos Biology. 10: e1001433. PMID 23209378 DOI: 10.1371/journal.pbio.1001433  0.88
2012 Wrann CD, Eguchi J, Bozec A, Xu Z, Mikkelsen T, Gimble J, Nave H, Wagner EF, Ong SE, Rosen ED. FOSL2 promotes leptin gene expression in human and mouse adipocytes. The Journal of Clinical Investigation. 122: 1010-21. PMID 22326952 DOI: 10.1172/JCI58431  0.88
2011 Gupta RK, Rosen ED, Spiegelman BM. Identifying novel transcriptional components controlling energy metabolism. Cell Metabolism. 14: 739-45. PMID 22152302 DOI: 10.1016/j.cmet.2011.11.007  0.88
2011 Jun LS, Siddall CP, Rosen ED. A minor role for lipocalin 2 in high-fat diet-induced glucose intolerance. American Journal of Physiology. Endocrinology and Metabolism. 301: E825-35. PMID 21771968 DOI: 10.1152/ajpendo.00147.2011  0.88
2011 Eguchi J, Wang X, Yu S, Kershaw EE, Chiu PC, Dushay J, Estall JL, Klein U, Maratos-Flier E, Rosen ED. Transcriptional control of adipose lipid handling by IRF4. Cell Metabolism. 13: 249-59. PMID 21356515 DOI: 10.1016/j.cmet.2011.02.005  0.88
2010 Bock J, Fukuyo Y, Kang S, Phipps ML, Alexandrov LB, Rasmussen KØ, Bishop AR, Rosen ED, Martinez JS, Chen HT, Rodriguez G, Alexandrov BS, Usheva A. Mammalian stem cells reprogramming in response to terahertz radiation. Plos One. 5: e15806. PMID 21209821 DOI: 10.1371/journal.pone.0015806  0.88
2010 Mikkelsen TS, Xu Z, Zhang X, Wang L, Gimble JM, Lander ES, Rosen ED. Comparative epigenomic analysis of murine and human adipogenesis. Cell. 143: 156-69. PMID 20887899 DOI: 10.1016/j.cell.2010.09.006  0.88
2007 Yan QW, Yang Q, Mody N, Graham TE, Hsu CH, Xu Z, Houstis NE, Kahn BB, Rosen ED. The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance. Diabetes. 56: 2533-40. PMID 17639021 DOI: 10.2337/db07-0007  0.88
2007 Mukherjee A, Sidis Y, Mahan A, Raher MJ, Xia Y, Rosen ED, Bloch KD, Thomas MK, Schneyer AL. FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults. Proceedings of the National Academy of Sciences of the United States of America. 104: 1348-53. PMID 17229845 DOI: 10.1073/pnas.0607966104  0.88
2006 Rosen ED, Spiegelman BM. Adipocytes as regulators of energy balance and glucose homeostasis. Nature. 444: 847-53. PMID 17167472 DOI: 10.1038/nature05483  0.88
2006 Sastre M, Dewachter I, Rossner S, Bogdanovic N, Rosen E, Borghgraef P, Evert BO, Dumitrescu-Ozimek L, Thal DR, Landreth G, Walter J, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. Proceedings of the National Academy of Sciences of the United States of America. 103: 443-8. PMID 16407166 DOI: 10.1073/pnas.0503839103  0.88
2004 Mix KS, Coon CI, Rosen ED, Suh N, Sporn MB, Brinckerhoff CE. Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling. Molecular Pharmacology. 65: 309-18. PMID 14742672 DOI: 10.1124/mol.65.2.309  0.88
2003 Rosen ED, Kulkarni RN, Sarraf P, Ozcan U, Okada T, Hsu CH, Eisenman D, Magnuson MA, Gonzalez FJ, Kahn CR, Spiegelman BM. Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis. Molecular and Cellular Biology. 23: 7222-9. PMID 14517292 DOI: 10.1128/MCB.23.20.7222-7229.2003  0.88
2003 Norris AW, Chen L, Fisher SJ, Szanto I, Ristow M, Jozsi AC, Hirshman MF, Rosen ED, Goodyear LJ, Gonzalez FJ, Spiegelman BM, Kahn CR. Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. The Journal of Clinical Investigation. 112: 608-18. PMID 12925701 DOI: 10.1172/JCI17305  0.88
2002 Mueller E, Drori S, Aiyer A, Yie J, Sarraf P, Chen H, Hauser S, Rosen ED, Ge K, Roeder RG, Spiegelman BM. Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms. The Journal of Biological Chemistry. 277: 41925-30. PMID 12200443 DOI: 10.1074/jbc.M206950200  0.88
2002 Rosen ED, Hsu CH, Wang X, Sakai S, Freeman MW, Gonzalez FJ, Spiegelman BM. C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes & Development. 16: 22-6. PMID 11782441 DOI: 10.1101/gad.948702  0.88
2001 Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW. The role of PPAR-gamma in macrophage differentiation and cholesterol uptake. Nature Medicine. 7: 41-7. PMID 11135614 DOI: 10.1038/83328  0.88
2000 Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM. Transcriptional regulation of adipogenesis. Genes & Development. 14: 1293-307. PMID 10837022  0.88
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