| Year |
Citation |
Score |
| 2024 |
Rosen ED, Kajimura S. Is it time to rethink the relationship between adipose inflammation and insulin resistance? The Journal of Clinical Investigation. 134. PMID 39225103 DOI: 10.1172/JCI184663 |
0.583 |
|
| 2024 |
Vargas-Castillo A, Sun Y, Smythers AL, Grauvogel L, Dumesic PA, Emont MP, Tsai LT, Rosen ED, Zammit NW, Shaffer SM, Ordonez M, Chouchani ET, Gygi SP, Wang T, Sharma AK, et al. Development of a functional beige fat cell line uncovers independent subclasses of cells expressing UCP1 and the futile creatine cycle. Cell Metabolism. PMID 39084217 DOI: 10.1016/j.cmet.2024.07.002 |
0.718 |
|
| 2024 |
Heyward FD, Liu N, Jacobs C, Machado NLS, Ivison R, Uner A, Srinivasan H, Patel SJ, Gulko A, Sermersheim T, Tsai L, Rosen ED. AgRP neuron cis-regulatory analysis across hunger states reveals that IRF3 mediates leptin's acute effects. Nature Communications. 15: 4646. PMID 38821928 DOI: 10.1038/s41467-024-48885-y |
0.77 |
|
| 2024 |
Yan S, Santoro A, Niphakis MJ, Pinto AM, Jacobs CL, Ahmad R, Suciu RM, Fonslow BR, Herbst-Graham RA, Ngo N, Henry CL, Herbst DM, Saghatelian A, Kahn BB, Rosen ED. Inflammation causes insulin resistance in mice via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels. Nature Communications. 15: 4605. PMID 38816388 DOI: 10.1038/s41467-024-48220-5 |
0.417 |
|
| 2024 |
Holman CD, Sakers AP, Calhoun RP, Cheng L, Fein EC, Jacobs C, Tsai L, Rosen ED, Seale P. Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming. Elife. 12. PMID 38775132 DOI: 10.7554/eLife.87756 |
0.628 |
|
| 2024 |
Ahmad Z, Kahloan W, Rosen ED. Transcriptional control of metabolism by interferon regulatory factors. Nature Reviews. Endocrinology. PMID 38769435 DOI: 10.1038/s41574-024-00990-0 |
0.318 |
|
| 2024 |
Kim K, Wann J, Kim HG, So J, Rosen ED, Roh HC. Uncoupling protein 1-driven Cre (Ucp1-Cre) is expressed in the epithelial cells of mammary glands and various non-adipose tissues. Molecular Metabolism. 101948. PMID 38677508 DOI: 10.1016/j.molmet.2024.101948 |
0.73 |
|
| 2023 |
Li E, Wang L, Wang D, Chi J, Lin Z, Smith GI, Klein S, Cohen P, Rosen ED. Control of lipolysis by a population of oxytocinergic sympathetic neurons. Nature. PMID 38093006 DOI: 10.1038/s41586-023-06830-x |
0.513 |
|
| 2023 |
Kim K, Wann J, Kim HG, So J, Rosen ED, Roh HC. Uncoupling protein 1-driven Cre ( ) is expressed in the epithelial cells of mammary glands and various non-adipose tissues. Biorxiv : the Preprint Server For Biology. PMID 37905088 DOI: 10.1101/2023.10.19.563175 |
0.729 |
|
| 2023 |
Emont MP, Jacobs C, Essene AL, Pant D, Tenen D, Colleluori G, Di Vincenzo A, Jørgensen AM, Dashti H, Stefek A, McGonagle E, Strobel S, Laber S, Agrawal S, Westcott GP, ... ... Rosen ED, et al. Author Correction: A single-cell atlas of human and mouse white adipose tissue. Nature. PMID 37495702 DOI: 10.1038/s41586-023-06445-2 |
0.758 |
|
| 2023 |
Emont MP, Rosen ED. Exploring the heterogeneity of white adipose tissue in mouse and man. Current Opinion in Genetics & Development. 80: 102045. PMID 37094486 DOI: 10.1016/j.gde.2023.102045 |
0.778 |
|
| 2023 |
Holman CD, Sakers AP, Calhoun RP, Cheng L, Fein EC, Jacobs C, Tsai L, Rosen ED, Seale P. Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming. Biorxiv : the Preprint Server For Biology. PMID 36993336 DOI: 10.1101/2023.03.20.533514 |
0.627 |
|
| 2022 |
Xiao H, Bozi LHM, Sun Y, Riley CL, Philip VM, Chen M, Li J, Zhang T, Mills EL, Emont MP, Sun W, Reddy A, Garrity R, Long J, Becher T, ... ... Rosen ED, et al. Architecture of the outbred brown fat proteome defines regulators of metabolic physiology. Cell. PMID 36334589 DOI: 10.1016/j.cell.2022.10.003 |
0.773 |
|
| 2022 |
Patel SJ, Liu N, Piaker S, Gulko A, Andrade ML, Heyward FD, Sermersheim T, Edinger N, Srinivasan H, Emont MP, Westcott GP, Luther J, Chung RT, Yan S, Kumari M, ... ... Rosen ED, et al. Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of . Science Translational Medicine. 14: eabh3831. PMID 35320000 DOI: 10.1126/scitranslmed.abh3831 |
0.789 |
|
| 2022 |
Emont MP, Jacobs C, Essene AL, Pant D, Tenen D, Colleluori G, Di Vincenzo A, Jørgensen AM, Dashti H, Stefek A, McGonagle E, Strobel S, Laber S, Agrawal S, Westcott GP, ... ... Rosen ED, et al. A single-cell atlas of human and mouse white adipose tissue. Nature. PMID 35296864 DOI: 10.1038/s41586-022-04518-2 |
0.803 |
|
| 2022 |
Westcott GP, Rosen ED. Crosstalk Between Adipose and Lymphatics in Health and Disease. Endocrinology. 163. PMID 34718498 DOI: 10.1210/endocr/bqab224 |
0.335 |
|
| 2021 |
Jiang Z, Zhao M, Voilquin L, Jung Y, Aikio MA, Sahai T, Dou FY, Roche AM, Carcamo-Orive I, Knowles JW, Wabitsch M, Appel EA, Maikawa CL, Camporez JP, Shulman GI, ... ... Rosen ED, et al. Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis. Cell Metabolism. PMID 34348115 DOI: 10.1016/j.cmet.2021.07.010 |
0.744 |
|
| 2021 |
Westcott GP, Emont MP, Li J, Jacobs C, Tsai L, Rosen ED. Mesothelial cells are not a source of adipocytes in mice. Cell Reports. 36: 109388. PMID 34260927 DOI: 10.1016/j.celrep.2021.109388 |
0.805 |
|
| 2021 |
Li J, Li E, Czepielewski RS, Chi J, Guo X, Han YH, Wang D, Wang L, Hu B, Dawes B, Jacobs C, Tenen D, Lin SJ, Lee B, Morris D, ... ... Rosen ED, et al. Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells. Cell Metabolism. PMID 34038712 DOI: 10.1016/j.cmet.2021.04.019 |
0.596 |
|
| 2021 |
Yan S, Kumari M, Xiao H, Jacobs C, Kochumon S, Jedrychowski M, Chouchani E, Ahmad R, Rosen ED. IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis. The Journal of Clinical Investigation. PMID 33571167 DOI: 10.1172/JCI144888 |
0.711 |
|
| 2020 |
Lontchi-Yimagou E, Kang S, Goyal A, Zhang K, You JY, Carey M, Jain S, Bhansali S, Kehlenbrink S, Guo P, Rosen E, Kishore P, Hawkins M. Insulin Sensitizing Effects of Vitamin D Repletion Mediated by Adipocyte Vitamin D Receptor: Studies in humans and mice. Molecular Metabolism. 101095. PMID 33045433 DOI: 10.1016/j.molmet.2020.101095 |
0.5 |
|
| 2020 |
Roh HC, Kumari M, Taleb S, Tenen D, Jacobs C, Lyubetskaya A, Tsai LT, Rosen ED. Adipocytes Fail to Maintain Cellular Identity During Obesity Due to Reduced PPARγ Activity and Elevated TGFβ-SMAD Signaling. Molecular Metabolism. 101086. PMID 32992037 DOI: 10.1016/j.molmet.2020.101086 |
0.725 |
|
| 2020 |
Hall JA, Ramachandran D, Roh HC, DiSpirito JR, Belchior T, Zushin PH, Palmer C, Hong S, Mina AI, Liu B, Deng Z, Aryal P, Jacobs C, Tenen D, Brown CW, ... ... Rosen ED, et al. Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3. Cell Metabolism. PMID 32941798 DOI: 10.1016/J.Cmet.2020.08.016 |
0.778 |
|
| 2019 |
Kazak L, Rahbani JF, Samborska B, Lu GZ, Jedrychowski MP, Lajoie M, Zhang S, Ramsay LC, Dou FY, Tenen D, Chouchani ET, Dzeja P, Watson IR, Tsai L, Rosen ED, et al. Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity. Nature Metabolism. 1: 360-370. PMID 31161155 DOI: 10.1038/s42255-019-0035-x |
0.79 |
|
| 2019 |
Jiao Y, Ahmed U, Sim MFM, Bejar A, Zhang X, Talukder MMU, Rice R, Flannick J, Podgornaia AI, Reilly DF, Engreitz JM, Kost-Alimova M, Hartland K, Mercader JM, Georges S, ... ... Rosen ED, et al. Discovering metabolic disease gene interactions by correlated effects on cellular morphology. Molecular Metabolism. PMID 30940487 DOI: 10.1016/J.Molmet.2019.03.001 |
0.39 |
|
| 2018 |
De Filippis E, Li T, Rosen ED. Exposure of adipocytes to bisphenol-A in vitro interferes with insulin action without enhancing adipogenesis. Plos One. 13: e0201122. PMID 30133442 DOI: 10.1371/Journal.Pone.0201122 |
0.459 |
|
| 2018 |
Kong X, Yao T, Zhou P, Kazak L, Tenen D, Lyubetskaya A, Dawes BA, Tsai L, Kahn BB, Spiegelman BM, Liu T, Rosen ED. Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin. Cell Metabolism. PMID 30078553 DOI: 10.1016/J.Cmet.2018.07.004 |
0.71 |
|
| 2018 |
Roh HC, Tsai LTY, Shao M, Tenen D, Shen Y, Kumari M, Lyubetskaya A, Jacobs C, Dawes B, Gupta RK, Rosen ED. Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity. Cell Metabolism. PMID 29657031 DOI: 10.1016/J.Cmet.2018.03.005 |
0.79 |
|
| 2018 |
Ahmad R, Al-Roub A, Kochumon S, Akther N, Thomas R, Kumari M, Koshy MS, Tiss A, Hannun YA, Tuomilehto J, Sindhu S, Rosen ED. The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 29632147 DOI: 10.4049/Jimmunol.1701552 |
0.421 |
|
| 2018 |
LONTCHI-YIMAGOU E, KANG S, ZHANG K, GOYAL A, YOU JY, KISHORE P, ROSEN E, HAWKINS M. Insulin Sensitizing Effects of Vitamin D Mediated through Reduced Adipose Tissue Inflammation and Fibrosis Diabetes. 67: 39-OR. DOI: 10.2337/Db18-39-Or |
0.558 |
|
| 2018 |
HEYWARD FD, ROSEN E. Cell Type–Specific Transcriptional and Epigenetic Profiles from a Rare Neuronal Population within the Arcuate Nucleus Diabetes. 67: 2430-PUB. DOI: 10.2337/Db18-2430-Pub |
0.78 |
|
| 2017 |
You D, Nilsson E, Tenen DE, Lyubetskaya A, Lo J, Jiang R, Deng J, Dawes BA, Vaag A, Ling C, Rosen ED, Kang S. Dnmt3a is an epigenetic mediator of adipose insulin resistance. Elife. 6. PMID 29091029 DOI: 10.7554/Elife.30766 |
0.579 |
|
| 2017 |
Shen Y, Roh HC, Kumari M, Rosen ED. Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding. Molecular Metabolism. 6: 1150-1160. PMID 29031716 DOI: 10.1016/J.Molmet.2017.06.013 |
0.751 |
|
| 2017 |
Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM. Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Cell Metabolism. 26: 693. PMID 28978428 DOI: 10.1016/J.Cmet.2017.09.007 |
0.805 |
|
| 2017 |
Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM. Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Cell Metabolism. PMID 28844881 DOI: 10.1016/J.Cmet.2017.08.009 |
0.812 |
|
| 2017 |
Kazak L, Chouchani ET, Stavrovskaya IG, Lu GZ, Jedrychowski MP, Egan DF, Kumari M, Kong X, Erickson BK, Szpyt J, Rosen ED, Murphy MP, Kristal BS, Gygi SP, Spiegelman BM. UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630339 DOI: 10.1073/Pnas.1705406114 |
0.775 |
|
| 2017 |
Guillermier C, Fazeli PK, Kim S, Lun M, Zuflacht JP, Milian J, Lee H, Francois-Saint-Cyr H, Horreard F, Larson D, Rosen ED, Lee RT, Lechene CP, Steinhauser ML. Imaging mass spectrometry demonstrates age-related decline in human adipose plasticity. Jci Insight. 2: e90349. PMID 28289709 DOI: 10.1172/Jci.Insight.90349 |
0.368 |
|
| 2017 |
Campbell JN, Macosko EZ, Fenselau H, Pers TH, Lyubetskaya A, Tenen D, Goldman M, Verstegen AM, Resch JM, McCarroll SA, Rosen ED, Lowell BB, Tsai LT. A molecular census of arcuate hypothalamus and median eminence cell types. Nature Neuroscience. PMID 28166221 DOI: 10.1038/Nn.4495 |
0.36 |
|
| 2017 |
Roh HC, Tsai LT, Lyubetskaya A, Tenen D, Kumari M, Rosen ED. Simultaneous Transcriptional and Epigenomic Profiling from Specific Cell Types within Heterogeneous Tissues In Vivo. Cell Reports. 18: 1048-1061. PMID 28122230 DOI: 10.1016/J.Celrep.2016.12.087 |
0.734 |
|
| 2017 |
You D, Nilsson E, Tenen DE, Lyubetskaya A, Lo JC, Jiang R, Deng J, Dawes BA, Vaag A, Ling C, Rosen ED, Kang S. Author response: Dnmt3a is an epigenetic mediator of adipose insulin resistance Elife. DOI: 10.7554/Elife.30766.042 |
0.55 |
|
| 2016 |
Rosen ED. Epigenomic and transcriptional control of insulin resistance. Journal of Internal Medicine. 280: 443-456. PMID 27739225 DOI: 10.1111/Joim.12547 |
0.468 |
|
| 2016 |
Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED. IRF3 promotes adipose inflammation and insulin resistance and represses browning. The Journal of Clinical Investigation. PMID 27400129 DOI: 10.1172/Jci86080 |
0.825 |
|
| 2016 |
Rosen ED. Burning Fat by Bugging the System. The New England Journal of Medicine. 374: 885-7. PMID 26962910 DOI: 10.1056/Nejmcibr1515457 |
0.335 |
|
| 2016 |
Kang S, Tsai LT, Rosen ED. Nuclear Mechanisms of Insulin Resistance. Trends in Cell Biology. PMID 26822036 DOI: 10.1016/J.Tcb.2016.01.002 |
0.553 |
|
| 2015 |
Herman MA, Rosen ED. Making Biological Sense of GWAS Data: Lessons from the FTO Locus. Cell Metabolism. 22: 538-9. PMID 26445508 DOI: 10.1016/J.Cmet.2015.09.018 |
0.348 |
|
| 2015 |
Rosen ED. Two paths to fat. Nature Cell Biology. 17: 360-1. PMID 25812519 DOI: 10.1038/Ncb3133 |
0.376 |
|
| 2015 |
Kang S, Tsai LT, Zhou Y, Evertts A, Xu S, Griffin MJ, Issner R, Whitton HJ, Garcia BA, Epstein CB, Mikkelsen TS, Rosen ED. Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis. Nature Cell Biology. 17: 44-56. PMID 25503565 DOI: 10.1038/Ncb3080 |
0.574 |
|
| 2014 |
Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, ... Rosen ED, et al. IRF4 is a key thermogenic transcriptional partner of PGC-1α. Cell. 158: 69-83. PMID 24995979 DOI: 10.1016/J.Cell.2014.04.049 |
0.8 |
|
| 2014 |
Long JZ, Svensson KJ, Tsai L, Zeng X, Roh HC, Kong X, Rao RR, Lou J, Lokurkar I, Baur W, Castellot JJ, Rosen ED, Spiegelman BM. A smooth muscle-like origin for beige adipocytes. Cell Metabolism. 19: 810-20. PMID 24709624 DOI: 10.1016/J.Cmet.2014.03.025 |
0.774 |
|
| 2014 |
Kang S, Kong X, Rosen ED. Adipocyte-specific transgenic and knockout models. Methods in Enzymology. 537: 1-16. PMID 24480338 DOI: 10.1016/B978-0-12-411619-1.00001-X |
0.62 |
|
| 2014 |
Rosen ED, Spiegelman BM. What we talk about when we talk about fat. Cell. 156: 20-44. PMID 24439368 DOI: 10.1016/J.Cell.2013.12.012 |
0.625 |
|
| 2013 |
Griffin MJ, Zhou Y, Kang S, Zhang X, Mikkelsen TS, Rosen ED. Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes. The Journal of Biological Chemistry. 288: 35925-39. PMID 24174531 DOI: 10.1074/Jbc.M113.491936 |
0.593 |
|
| 2013 |
Bozec A, Bakiri L, Jimenez M, Rosen ED, Catalá-Lehnen P, Schinke T, Schett G, Amling M, Wagner EF. Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism. Journal of Cell Science. 126: 5432-40. PMID 24046454 DOI: 10.1242/Jcs.134510 |
0.426 |
|
| 2013 |
Eguchi J, Kong X, Tenta M, Wang X, Kang S, Rosen ED. Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization. Diabetes. 62: 3394-403. PMID 23835343 DOI: 10.2337/Db12-1327 |
0.653 |
|
| 2013 |
Lee KY, Russell SJ, Ussar S, Boucher J, Vernochet C, Mori MA, Smyth G, Rourk M, Cederquist C, Rosen ED, Kahn BB, Kahn CR. Lessons on conditional gene targeting in mouse adipose tissue. Diabetes. 62: 864-74. PMID 23321074 DOI: 10.2337/Db12-1089 |
0.375 |
|
| 2012 |
Wrann CD, Rosen ED. New insights into adipocyte-specific leptin gene expression. Adipocyte. 1: 168-172. PMID 23700528 DOI: 10.4161/adip.20574 |
0.334 |
|
| 2012 |
Kang S, Akerblad P, Kiviranta R, Gupta RK, Kajimura S, Griffin MJ, Min J, Baron R, Rosen ED. Regulation of early adipose commitment by Zfp521. Plos Biology. 10: e1001433. PMID 23209378 DOI: 10.1371/Journal.Pbio.1001433 |
0.792 |
|
| 2012 |
Wrann CD, Eguchi J, Bozec A, Xu Z, Mikkelsen T, Gimble J, Nave H, Wagner EF, Ong SE, Rosen ED. FOSL2 promotes leptin gene expression in human and mouse adipocytes. The Journal of Clinical Investigation. 122: 1010-21. PMID 22326952 DOI: 10.1172/Jci58431 |
0.479 |
|
| 2011 |
Gupta RK, Rosen ED, Spiegelman BM. Identifying novel transcriptional components controlling energy metabolism. Cell Metabolism. 14: 739-45. PMID 22152302 DOI: 10.1016/J.Cmet.2011.11.007 |
0.737 |
|
| 2011 |
Jun LS, Siddall CP, Rosen ED. A minor role for lipocalin 2 in high-fat diet-induced glucose intolerance. American Journal of Physiology. Endocrinology and Metabolism. 301: E825-35. PMID 21771968 DOI: 10.1152/Ajpendo.00147.2011 |
0.816 |
|
| 2011 |
Eguchi J, Wang X, Yu S, Kershaw EE, Chiu PC, Dushay J, Estall JL, Klein U, Maratos-Flier E, Rosen ED. Transcriptional control of adipose lipid handling by IRF4. Cell Metabolism. 13: 249-59. PMID 21356515 DOI: 10.1016/J.Cmet.2011.02.005 |
0.741 |
|
| 2010 |
Bock J, Fukuyo Y, Kang S, Phipps ML, Alexandrov LB, Rasmussen KØ, Bishop AR, Rosen ED, Martinez JS, Chen HT, Rodriguez G, Alexandrov BS, Usheva A. Mammalian stem cells reprogramming in response to terahertz radiation. Plos One. 5: e15806. PMID 21209821 DOI: 10.1371/Journal.Pone.0015806 |
0.5 |
|
| 2010 |
Mikkelsen TS, Xu Z, Zhang X, Wang L, Gimble JM, Lander ES, Rosen ED. Comparative epigenomic analysis of murine and human adipogenesis. Cell. 143: 156-69. PMID 20887899 DOI: 10.1016/J.Cell.2010.09.006 |
0.333 |
|
| 2009 |
Rosen E, Eguchi J, Xu Z. Transcriptional targets in adipocyte biology. Expert Opinion On Therapeutic Targets. 13: 975-86. PMID 19534570 DOI: 10.1517/14728220903039706 |
0.465 |
|
| 2008 |
Xu Z, Yu S, Hsu CH, Eguchi J, Rosen ED. The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 2421-6. PMID 18250317 DOI: 10.1073/Pnas.0707082105 |
0.438 |
|
| 2008 |
Eguchi J, Yan QW, Schones DE, Kamal M, Hsu CH, Zhang MQ, Crawford GE, Rosen ED. Interferon regulatory factors are transcriptional regulators of adipogenesis. Cell Metabolism. 7: 86-94. PMID 18177728 DOI: 10.1016/J.Cmet.2007.11.002 |
0.364 |
|
| 2007 |
Yan QW, Yang Q, Mody N, Graham TE, Hsu CH, Xu Z, Houstis NE, Kahn BB, Rosen ED. The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance. Diabetes. 56: 2533-40. PMID 17639021 DOI: 10.2337/Db07-0007 |
0.501 |
|
| 2007 |
Mukherjee A, Sidis Y, Mahan A, Raher MJ, Xia Y, Rosen ED, Bloch KD, Thomas MK, Schneyer AL. FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults. Proceedings of the National Academy of Sciences of the United States of America. 104: 1348-53. PMID 17229845 DOI: 10.1073/Pnas.0607966104 |
0.447 |
|
| 2007 |
Jimenez MA, Akerblad P, Sigvardsson M, Rosen ED. Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade. Molecular and Cellular Biology. 27: 743-57. PMID 17060461 DOI: 10.1128/Mcb.01557-06 |
0.333 |
|
| 2006 |
Rosen ED, Spiegelman BM. Adipocytes as regulators of energy balance and glucose homeostasis. Nature. 444: 847-53. PMID 17167472 DOI: 10.1038/Nature05483 |
0.635 |
|
| 2006 |
Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nature Reviews. Molecular Cell Biology. 7: 885-96. PMID 17139329 DOI: 10.1038/Nrm2066 |
0.401 |
|
| 2006 |
Houstis N, Rosen ED, Lander ES. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature. 440: 944-8. PMID 16612386 DOI: 10.1038/Nature04634 |
0.397 |
|
| 2005 |
Rosen ED. The transcriptional basis of adipocyte development. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 73: 31-4. PMID 15936931 DOI: 10.1016/J.Plefa.2005.04.004 |
0.421 |
|
| 2004 |
Xie J, Zhu H, Larade K, Ladoux A, Seguritan A, Chu M, Ito S, Bronson RT, Leiter EH, Zhang CY, Rosen ED, Bunn HF. Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. Proceedings of the National Academy of Sciences of the United States of America. 101: 10750-5. PMID 15247412 DOI: 10.1073/Pnas.0404044101 |
0.387 |
|
| 2003 |
Rosen ED. Energy balance: a new role for PPARalpha. Current Biology : Cb. 13: R961-3. PMID 14680654 DOI: 10.1016/J.Cub.2003.11.043 |
0.31 |
|
| 2003 |
Rosen ED, Kulkarni RN, Sarraf P, Ozcan U, Okada T, Hsu CH, Eisenman D, Magnuson MA, Gonzalez FJ, Kahn CR, Spiegelman BM. Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis. Molecular and Cellular Biology. 23: 7222-9. PMID 14517292 DOI: 10.1128/Mcb.23.20.7222-7229.2003 |
0.559 |
|
| 2003 |
Norris AW, Chen L, Fisher SJ, Szanto I, Ristow M, Jozsi AC, Hirshman MF, Rosen ED, Goodyear LJ, Gonzalez FJ, Spiegelman BM, Kahn CR. Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. The Journal of Clinical Investigation. 112: 608-18. PMID 12925701 DOI: 10.1172/Jci17305 |
0.608 |
|
| 2002 |
Rosen ED. The molecular control of adipogenesis, with special reference to lymphatic pathology. Annals of the New York Academy of Sciences. 979: 143-58; discussion 1. PMID 12543724 DOI: 10.1111/J.1749-6632.2002.Tb04875.X |
0.501 |
|
| 2002 |
Mueller E, Drori S, Aiyer A, Yie J, Sarraf P, Chen H, Hauser S, Rosen ED, Ge K, Roeder RG, Spiegelman BM. Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms. The Journal of Biological Chemistry. 277: 41925-30. PMID 12200443 DOI: 10.1074/Jbc.M206950200 |
0.535 |
|
| 2002 |
Rosen ED, Hsu CH, Wang X, Sakai S, Freeman MW, Gonzalez FJ, Spiegelman BM. C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes & Development. 16: 22-6. PMID 11782441 DOI: 10.1101/Gad.948702 |
0.538 |
|
| 2001 |
Rosen ED, Spiegelman BM. PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth. The Journal of Biological Chemistry. 276: 37731-4. PMID 11459852 DOI: 10.1074/Jbc.R100034200 |
0.545 |
|
| 2001 |
Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW. The role of PPAR-gamma in macrophage differentiation and cholesterol uptake. Nature Medicine. 7: 41-7. PMID 11135614 DOI: 10.1038/83328 |
0.526 |
|
| 2001 |
Rosen ED, Spiegelman BM. Molecular regulation of adipogenesis. Annual Review of Cell and Developmental Biology. 16: 145-71. PMID 11031233 DOI: 10.1146/Annurev.Cellbio.16.1.145 |
0.594 |
|
| 2000 |
Rosen ED, Spiegelman BM. Peroxisome proliferator-activated receptor gamma ligands and atherosclerosis: ending the heartache. The Journal of Clinical Investigation. 106: 629-31. PMID 10974014 DOI: 10.1172/Jci10909 |
0.631 |
|
| 2000 |
Yoon JC, Chickering TW, Rosen ED, Dussault B, Qin Y, Soukas A, Friedman JM, Holmes WE, Spiegelman BM. Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Molecular and Cellular Biology. 20: 5343-9. PMID 10866690 DOI: 10.1128/Mcb.20.14.5343-5349.2000 |
0.625 |
|
| 2000 |
Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM. Transcriptional regulation of adipogenesis. Genes & Development. 14: 1293-307. PMID 10837022 DOI: 10.1101/Gad.14.11.1293 |
0.596 |
|
| 1999 |
Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, Milstone DS, Spiegelman BM, Mortensen RM. PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro. Molecular Cell. 4: 611-7. PMID 10549292 DOI: 10.1016/S1097-2765(00)80211-7 |
0.602 |
|
| 1999 |
Wu Z, Rosen ED, Brun R, Hauser S, Adelmant G, Troy AE, McKeon C, Darlington GJ, Spiegelman BM. Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Molecular Cell. 3: 151-8. PMID 10078198 DOI: 10.1016/S1097-2765(00)80306-8 |
0.541 |
|
| 1999 |
Rosen ED, Spiegelman BM. Tumor necrosis factor-α as a mediator of the insulin resistance of obesity Current Opinion in Endocrinology & Diabetes. 6: 170-176. DOI: 10.1097/00060793-199904000-00014 |
0.562 |
|
| 1991 |
O'Donnell AL, Rosen ED, Darling DS, Koenig RJ. Thyroid hormone receptor mutations that interfere with transcriptional activation also interfere with receptor interaction with a nuclear protein Molecular Endocrinology. 5: 94-99. PMID 1850112 DOI: 10.1210/Mend-5-1-94 |
0.575 |
|
| 1991 |
Rosen ED, O'Donnell AL, Koenig RJ. Protein-protein interactions involving erbA superfamily receptors: through the TRAPdoor Molecular and Cellular Endocrinology. 78. PMID 1682188 DOI: 10.1016/0303-7207(91)90175-R |
0.598 |
|
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