108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bennett CF, O'Malley KE, Perry EA, Balsa E, Latorre-Muro P, Riley CL, Luo C, Jedrychowski M, Gygi SP, Puigserver P. Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly. Nature Chemical Biology. PMID 33723432 DOI: 10.1038/s41589-021-00772-z  0.4
2021 Latorre-Muro P, O'Malley KE, Bennett CF, Perry EA, Balsa E, Tavares CDJ, Jedrychowski M, Gygi SP, Puigserver P. A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation. Cell Metabolism. PMID 33592173 DOI: 10.1016/j.cmet.2021.01.013  0.4
2021 Perry EA, Bennett CF, Luo C, Balsa E, Jedrychowski M, O'Malley KE, Latorre-Muro P, Ladley RP, Reda K, Wright PM, Gygi SP, Myers AG, Puigserver P. Tetracyclines promote survival and fitness in mitochondrial disease models. Nature Metabolism. PMID 33462515 DOI: 10.1038/s42255-020-00334-y  0.4
2019 Balsa E, Soustek MS, Thomas A, Cogliati S, García-Poyatos C, Martín-García E, Jedrychowski M, Gygi SP, Enriquez JA, Puigserver P. ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis. Molecular Cell. PMID 31023583 DOI: 10.1016/J.Molcel.2019.03.031  0.4
2018 Soustek MS, Balsa E, Barrow JJ, Jedrychowski M, Vogel R, Jan Smeitink, Gygi SP, Puigserver P. Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells. Cell Death & Disease. 9: 658. PMID 29855477 DOI: 10.1038/S41419-018-0696-5  0.4
2017 Puigserver P, Luo C, Balsa E, Thomas A, Hatting M, Jedrychowski M, Gygi SP, Widlund HR. ERRα maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-elevated Melanomas. Molecular Cancer Research : McR. PMID 28596418 DOI: 10.1158/1541-7786.Mcr-17-0143  0.4
2017 Sharabi K, Lin H, Tavares CD, Dominy JE, Camporez JP, Perry RJ, Schilling R, Rines AK, Lee J, Hickey M, Bennion M, Palmer M, Nag PP, Bittker JA, Perez J, ... ... Puigserver P, et al. Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 169: 148-160.e15. PMID 28340340 DOI: 10.1016/J.Cell.2017.03.001  0.4
2016 Barrow JJ, Balsa E, Verdeguer F, Tavares CD, Soustek MS, Hollingsworth LR, Jedrychowski M, Vogel R, Paulo JA, Smeitink J, Gygi SP, Doench J, Root DE, Puigserver P. Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations. Molecular Cell. PMID 27666594 DOI: 10.1016/J.Molcel.2016.08.023  0.4
2016 Rines AK, Sharabi K, Tavares CD, Puigserver P. Targeting hepatic glucose metabolism in the treatment of type 2 diabetes. Nature Reviews. Drug Discovery. PMID 27516169 DOI: 10.1038/Nrd.2016.151  0.88
2016 Tavares CD, Sharabi K, Dominy JE, Lee Y, Isasa M, Orozco JM, Jedrychowski MP, Kamenecka TM, Griffin PR, Gygi SP, Puigserver P. The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyl Transferase and the PGC-1α Transcriptional Coactivator. The Journal of Biological Chemistry. PMID 27022023 DOI: 10.1074/Jbc.M115.706200  0.4
2016 Luo C, Puigserver P. Stem cells: Dietary fat promotes intestinal dysregulation. Nature. 531: 42-3. PMID 26935693 DOI: 10.1038/531042A  0.88
2016 Lee G, Won HS, Lee YM, Choi JW, Oh TI, Jang JH, Choi DK, Lim BO, Kim YJ, Park JW, Puigserver P, Lim JH. Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation. Scientific Reports. 6: 18928. PMID 26740011 DOI: 10.1038/Srep18928  0.88
2015 Verdeguer F, Soustek MS, Hatting M, Blättler SM, McDonald D, Barrow JJ, Puigserver P. Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity. Molecular and Cellular Biology. PMID 26503783 DOI: 10.1128/Mcb.00722-15  0.88
2015 Soustek MS, Puigserver P. Interrupting synoviolin play at the ER: a plausible action to elevate mitochondrial energetics and silence obesity. The Embo Journal. 34: 981-3. PMID 25736377 DOI: 10.15252/Embj.201591240  0.88
2015 Rines AK, Verdeguer F, Puigserver P. Adenosine activates thermogenic adipocytes. Cell Research. 25: 155-6. PMID 25449131 DOI: 10.1038/Cr.2014.157  0.88
2015 Balsa-Martinez E, Puigserver P. Cancer Cells Hijack Gluconeogenic Enzymes to Fuel Cell Growth Molecular Cell. 60: 509-511. DOI: 10.1016/j.molcel.2015.11.005  0.88
2015 Sharabi K, Tavares CDJ, Rines AK, Puigserver P. Molecular pathophysiology of hepatic glucose production Molecular Aspects of Medicine. 46: 21-33. DOI: 10.1016/j.mam.2015.09.003  0.88
2014 Chow JD, Lawrence RT, Healy ME, Dominy JE, Liao JA, Breen DS, Byrne FL, Kenwood BM, Lackner C, Okutsu S, Mas VR, Caldwell SH, Tomsig JL, Cooney GJ, Puigserver PB, et al. Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation. Molecular Metabolism. 3: 419-31. PMID 24944901 DOI: 10.1016/J.Molmet.2014.02.004  0.88
2014 Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P. Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 510: 547-51. PMID 24870244 DOI: 10.1038/Nature13267  0.88
2014 Lim JH, Luo C, Vazquez F, Puigserver P. Targeting mitochondrial oxidative metabolism in melanoma causes metabolic compensation through glucose and glutamine utilization. Cancer Research. 74: 3535-45. PMID 24812272 DOI: 10.1158/0008-5472.Can-13-2893-T  0.88
2014 Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, ... ... Puigserver P, et al. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 508: 258-62. PMID 24717514 DOI: 10.1038/Nature13198  0.88
2014 Hall JA, Tabata M, Rodgers JT, Puigserver P. USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy. Molecular Endocrinology (Baltimore, Md.). 28: 912-24. PMID 24694308 DOI: 10.1210/Me.2013-1420  0.88
2014 Verdeguer F, Blättler SM, Cunningham JT, Hall JA, Chim H, Puigserver P. Decreased genetic dosage of hepatic Yin Yang 1 causes diabetic-like symptoms. Molecular Endocrinology (Baltimore, Md.). 28: 308-16. PMID 24467246 DOI: 10.1210/Me.2013-1173  0.88
2014 Tabata M, Rodgers JT, Hall JA, Lee Y, Jedrychowski MP, Gygi SP, Puigserver P. Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex. Diabetes. 63: 1519-32. PMID 24458359 DOI: 10.2337/Db13-1304  0.88
2013 Dominy J, Puigserver P, Cantó C. In vivo measurement of the acetylation state of sirtuin substrates as a proxy for sirtuin activity. Methods in Molecular Biology (Clifton, N.J.). 1077: 217-37. PMID 24014410 DOI: 10.1007/978-1-62703-637-5_15  0.88
2013 Dominy JE, Puigserver P. Mitochondrial biogenesis through activation of nuclear signaling proteins. Cold Spring Harbor Perspectives in Biology. 5. PMID 23818499 DOI: 10.1101/Cshperspect.A015008  0.88
2013 Hall JA, Dominy JE, Lee Y, Puigserver P. The sirtuin family's role in aging and age-associated pathologies. The Journal of Clinical Investigation. 123: 973-9. PMID 23454760 DOI: 10.1172/Jci64094  0.88
2013 Vazquez F, Lim JH, Chim H, Bhalla K, Girnun G, Pierce K, Clish CB, Granter SR, Widlund HR, Spiegelman BM, Puigserver P. PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell. 23: 287-301. PMID 23416000 DOI: 10.1016/J.Ccr.2012.11.020  0.88
2013 Lim JH, Gerhart-Hines Z, Dominy JE, Lee Y, Kim S, Tabata M, Xiang YK, Puigserver P. Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex. The Journal of Biological Chemistry. 288: 7117-26. PMID 23329830 DOI: 10.1074/Jbc.M112.415729  0.88
2012 Dominy JE, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, ... Puigserver P, et al. The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. Molecular Cell. 48: 900-13. PMID 23142079 DOI: 10.1016/J.Molcel.2012.09.030  0.88
2012 Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, ... Puigserver P, et al. TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell. 151: 96-110. PMID 23021218 DOI: 10.1016/J.Cell.2012.08.034  0.88
2012 Carracedo A, Weiss D, Leliaert AK, Bhasin M, de Boer VC, Laurent G, Adams AC, Sundvall M, Song SJ, Ito K, Finley LS, Egia A, Libermann T, Gerhart-Hines Z, Puigserver P, et al. A metabolic prosurvival role for PML in breast cancer. The Journal of Clinical Investigation. 122: 3088-100. PMID 22886304 DOI: 10.1172/Jci62129  0.88
2012 Blättler SM, Verdeguer F, Liesa M, Cunningham JT, Vogel RO, Chim H, Liu H, Romanino K, Shirihai OS, Vazquez F, Rüegg MA, Shi Y, Puigserver P. Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle. Molecular and Cellular Biology. 32: 3333-46. PMID 22711985 DOI: 10.1128/Mcb.00337-12  0.88
2012 Blättler SM, Cunningham JT, Verdeguer F, Chim H, Haas W, Liu H, Romanino K, Rüegg MA, Gygi SP, Shi Y, Puigserver P. Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling. Cell Metabolism. 15: 505-17. PMID 22482732 DOI: 10.1016/J.Cmet.2012.03.008  0.88
2012 Dominy JE, Vazquez F, Puigserver P. Glycine decarboxylase cleaves a "malignant" metabolic path to promote tumor initiation. Cancer Cell. 21: 143-5. PMID 22340586 DOI: 10.1016/J.Ccr.2012.01.019  0.88
2012 Kelly TJ, Souza AL, Clish CB, Puigserver P. A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1α stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like Molecular and Cellular Biology. 32: 898. DOI: 10.1128/MCB.06639-11  0.88
2011 Dominy JE, Gerhart-Hines Z, Puigserver P. Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming. Cold Spring Harbor Symposia On Quantitative Biology. 76: 203-9. PMID 22371372 DOI: 10.1101/Sqb.2012.76.010843  0.88
2011 Gerhart-Hines Z, Dominy JE, Blättler SM, Jedrychowski MP, Banks AS, Lim JH, Chim H, Gygi SP, Puigserver P. The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+). Molecular Cell. 44: 851-63. PMID 22195961 DOI: 10.1016/J.Molcel.2011.12.005  0.88
2011 Romanino K, Mazelin L, Albert V, Conjard-Duplany A, Lin S, Bentzinger CF, Handschin C, Puigserver P, Zorzato F, Schaeffer L, Gangloff YG, Rüegg MA. Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 108: 20808-13. PMID 22143799 DOI: 10.1073/Pnas.1111448109  0.88
2011 Bhalla K, Hwang BJ, Dewi RE, Ou L, Twaddel W, Fang HB, Vafai SB, Vazquez F, Puigserver P, Boros L, Girnun GD. PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis. Cancer Research. 71: 6888-98. PMID 21914785 DOI: 10.1158/0008-5472.Can-11-1011  0.88
2011 Kelly TJ, Souza AL, Clish CB, Puigserver P. A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1alpha stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like. Molecular and Cellular Biology. 31: 2696-706. PMID 21555452 DOI: 10.1128/Mcb.01242-10  0.88
2011 Rodgers JT, Vogel RO, Puigserver P. Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt. Molecular Cell. 41: 471-9. PMID 21329884 DOI: 10.1016/J.Molcel.2011.02.007  0.88
2010 Dominy JE, Puigserver P. Nuclear FoxO1 inflames insulin resistance. The Embo Journal. 29: 4068-9. PMID 21157481 DOI: 10.1038/Emboj.2010.305  0.88
2010 Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, ... ... Puigserver P, et al. Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes & Development. 24: 1403-17. PMID 20595232 DOI: 10.1101/Gad.1901210  0.88
2010 Rodgers JT, Haas W, Gygi SP, Puigserver P. Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis. Cell Metabolism. 11: 23-34. PMID 20074525 DOI: 10.1016/J.Cmet.2009.11.006  0.88
2010 Dominy JE, Lee Y, Gerhart-Hines Z, Puigserver P. Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. Biochimica Et Biophysica Acta. 1804: 1676-83. PMID 20005308 DOI: 10.1016/J.Bbapap.2009.11.023  0.88
2009 Cheng Z, Guo S, Copps K, Dong X, Kollipara R, Rodgers JT, Depinho RA, Puigserver P, White MF. Foxo1 integrates insulin signaling with mitochondrial function in the liver. Nature Medicine. 15: 1307-11. PMID 19838201 DOI: 10.1038/Nm.2049  0.88
2009 Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature. 461: 109-13. PMID 19693011 DOI: 10.1038/Nature08268  0.88
2009 Kelly TJ, Lerin C, Haas W, Gygi SP, Puigserver P. GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation. The Journal of Biological Chemistry. 284: 19945-52. PMID 19491097 DOI: 10.1074/Jbc.M109.015164  0.88
2009 Cantó C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P, Auwerx J. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature. 458: 1056-60. PMID 19262508 DOI: 10.1038/Nature07813  0.88
2009 Rodgers JT, Puigserver P. Insulin resistance: beta-arrestin development. Cell Research. 19: 275-6. PMID 19252509 DOI: 10.1038/Cr.2009.22  0.88
2009 Housley MP, Udeshi ND, Rodgers JT, Shabanowitz J, Puigserver P, Hunt DF, Hart GW. A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose. The Journal of Biological Chemistry. 284: 5148-57. PMID 19103600 DOI: 10.1074/Jbc.M808890200  0.88
2009 Suchankova G, Nelson LE, Gerhart-Hines Z, Kelly M, Gauthier MS, Saha AK, Ido Y, Puigserver P, Ruderman NB. Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells. Biochemical and Biophysical Research Communications. 378: 836-41. PMID 19071085 DOI: 10.1016/J.Bbrc.2008.11.130  0.88
2008 Coste A, Louet JF, Lagouge M, Lerin C, Antal MC, Meziane H, Schoonjans K, Puigserver P, O'Malley BW, Auwerx J. The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proceedings of the National Academy of Sciences of the United States of America. 105: 17187-92. PMID 18957541 DOI: 10.1073/Pnas.0808207105  0.88
2008 Housley MP, Rodgers JT, Udeshi ND, Kelly TJ, Shabanowitz J, Hunt DF, Puigserver P, Hart GW. O-GlcNAc regulates FoxO activation in response to glucose. The Journal of Biological Chemistry. 283: 16283-92. PMID 18420577 DOI: 10.1074/Jbc.M802240200  0.88
2008 Rodgers JT, Lerin C, Gerhart-Hines Z, Puigserver P. Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. Febs Letters. 582: 46-53. PMID 18036349 DOI: 10.1016/J.Febslet.2007.11.034  0.88
2007 Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P. mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature. 450: 736-40. PMID 18046414 DOI: 10.1038/Nature06322  0.88
2007 Rodgers JT, Puigserver P. Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1. Proceedings of the National Academy of Sciences of the United States of America. 104: 12861-6. PMID 17646659 DOI: 10.1073/Pnas.0702509104  0.88
2007 Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. The Embo Journal. 26: 3169-79. PMID 17581637 DOI: 10.1038/Sj.Emboj.7601758  0.88
2007 Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, Mostoslavsky R, Alt FW, Wu Z, Puigserver P. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. The Embo Journal. 26: 1913-23. PMID 17347648 DOI: 10.1038/Sj.Emboj.7601633  0.88
2007 Rodgers JT, Puigserver P. Receptor feasts on sugar and cholesterol. Nature Medicine. 13: 128-9. PMID 17290267 DOI: 10.1038/Nm0207-128  0.88
2006 Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell. 127: 1109-22. PMID 17112576 DOI: 10.1016/J.Cell.2006.11.013  0.88
2006 Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, ... ... Puigserver P, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 444: 337-42. PMID 17086191 DOI: 10.1038/Nature05354  0.88
2006 Cha SH, Rodgers JT, Puigserver P, Chohnan S, Lane MD. Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha. Proceedings of the National Academy of Sciences of the United States of America. 103: 15410-5. PMID 17030788 DOI: 10.1073/Pnas.0607334103  0.88
2006 Lerin C, Rodgers JT, Kalume DE, Kim SH, Pandey A, Puigserver P. GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metabolism. 3: 429-38. PMID 16753578 DOI: 10.1016/J.Cmet.2006.04.013  0.88
2006 Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L, Zhao W, Thiyagarajan M, MacGrogan D, Rodgers JT, Puigserver P, Sadoshima J, Deng H, Pedrini S, Gandy S, et al. Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. The Journal of Biological Chemistry. 281: 21745-54. PMID 16751189 DOI: 10.1074/Jbc.M602909200  0.88
2006 Rodgers JT, Puigserver P. Certainly can't live without this: SIRT6. Cell Metabolism. 3: 77-8. PMID 16459306 DOI: 10.1016/J.Cmet.2006.01.009  0.88
2006 Puigserver P, Rodgers JT. Foxa2, a novel transcriptional regulator of insulin sensitivity. Nature Medicine. 12: 38-9. PMID 16397559 DOI: 10.1038/Nm0106-38  0.88
2006 Puigserver P. Author's comments Nature Medicine. 12: 36. DOI: 10.1038/nm0106-36  0.88
2005 Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature. 434: 113-8. PMID 15744310 DOI: 10.1038/Nature03354  0.88
2005 Puigserver P. Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha. International Journal of Obesity (2005). 29: S5-9. PMID 15711583 DOI: 10.1038/Sj.Ijo.0802905  0.88
2004 Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S, Yang W, Altshuler D, Puigserver P, Patterson N, Willy PJ, Schulman IG, Heyman RA, Lander ES, Spiegelman BM. Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. Proceedings of the National Academy of Sciences of the United States of America. 101: 6570-5. PMID 15100410 DOI: 10.1073/Pnas.0401401101  0.88
2004 Cao W, Daniel KW, Robidoux J, Puigserver P, Medvedev AV, Bai X, Floering LM, Spiegelman BM, Collins S. p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. Molecular and Cellular Biology. 24: 3057-67. PMID 15024092 DOI: 10.1128/Mcb.24.7.3057-3067.2004  0.88
2004 Fan M, Rhee J, St-Pierre J, Handschin C, Puigserver P, Lin J, Jäeger S, Erdjument-Bromage H, Tempst P, Spiegelman BM. Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. Genes & Development. 18: 278-89. PMID 14744933 DOI: 10.1101/Gad.1152204  0.88
2003 Yoon JC, Xu G, Deeney JT, Yang SN, Rhee J, Puigserver P, Levens AR, Yang R, Zhang CY, Lowell BB, Berggren PO, Newgard CB, Bonner-Weir S, Weir G, Spiegelman BM. Suppression of beta cell energy metabolism and insulin release by PGC-1alpha. Developmental Cell. 5: 73-83. PMID 12852853 DOI: 10.1016/S1534-5807(03)00170-9  0.88
2003 Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, RidderstrÃ¥le M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nature Genetics. 34: 267-73. PMID 12808457 DOI: 10.1038/Ng1180  0.88
2003 Lin J, Tarr PT, Yang R, Rhee J, Puigserver P, Newgard CB, Spiegelman BM. PGC-1beta in the regulation of hepatic glucose and energy metabolism. The Journal of Biological Chemistry. 278: 30843-8. PMID 12807885 DOI: 10.1074/Jbc.M303643200  0.88
2003 Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature. 423: 550-5. PMID 12754525 DOI: 10.1038/Nature01667  0.88
2003 Rhee J, Inoue Y, Yoon JC, Puigserver P, Fan M, Gonzalez FJ, Spiegelman BM. Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 4012-7. PMID 12651943 DOI: 10.1073/Pnas.0730870100  0.88
2003 Puigserver P, Spiegelman BM. Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocrine Reviews. 24: 78-90. PMID 12588810 DOI: 10.1210/Er.2002-0012  0.88
2003 Tritos NA, Mastaitis JW, Kokkotou EG, Puigserver P, Spiegelman BM, Maratos-Flier E. Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1alpha) expression in the murine brain. Brain Research. 961: 255-60. PMID 12531492 DOI: 10.1016/S0006-8993(02)03961-6  0.88
2002 Lin J, Wu H, Tarr PT, Zhang CY, Wu Z, Boss O, Michael LF, Puigserver P, Isotani E, Olson EN, Lowell BB, Bassel-Duby R, Spiegelman BM. Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature. 418: 797-801. PMID 12181572 DOI: 10.1038/Nature00904  0.88
2002 Lin J, Puigserver P, Donovan J, Tarr P, Spiegelman BM. Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor. The Journal of Biological Chemistry. 277: 1645-8. PMID 11733490 DOI: 10.1074/Jbc.C100631200  0.88
2001 Puigserver P, Rhee J, Lin J, Wu Z, Yoon JC, Zhang CY, Krauss S, Mootha VK, Lowell BB, Spiegelman BM. Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Molecular Cell. 8: 971-82. PMID 11741533 DOI: 10.1016/S1097-2765(01)00390-2  0.88
2001 Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature. 413: 179-83. PMID 11557984 DOI: 10.1038/35093131  0.88
2001 Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature. 413: 131-8. PMID 11557972 DOI: 10.1038/35093050  0.88
2001 Michael LF, Wu Z, Cheatham RB, Puigserver P, Adelmant G, Lehman JJ, Kelly DP, Spiegelman BM. Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proceedings of the National Academy of Sciences of the United States of America. 98: 3820-5. PMID 11274399 DOI: 10.1073/Pnas.061035098  0.88
2000 Spiegelman BM, Puigserver P, Wu Z. Regulation of adipogenesis and energy balance by PPARgamma and PGC-1. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 24: S8-10. PMID 11126248 DOI: 10.1038/Sj.Ijo.0801492  0.88
2000 Monsalve M, Wu Z, Adelmant G, Puigserver P, Fan M, Spiegelman BM. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Molecular Cell. 6: 307-16. PMID 10983978 DOI: 10.1016/S1097-2765(00)00031-9  0.88
2000 Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM. Transcriptional regulation of adipogenesis. Genes & Development. 14: 1293-307. PMID 10837022 DOI: 10.1101/Gad.14.11.1293  0.88
2000 Tcherepanova I, Puigserver P, Norris JD, Spiegelman BM, McDonnell DP. Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. The Journal of Biological Chemistry. 275: 16302-8. PMID 10748020 DOI: 10.1074/Jbc.M001364200  0.88
1999 Wu Z, Puigserver P, Spiegelman BM. Transcriptional activation of adipogenesis. Current Opinion in Cell Biology. 11: 689-94. PMID 10600710 DOI: 10.1016/S0955-0674(99)00037-X  0.88
1999 Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman BM. Activation of PPARgamma coactivator-1 through transcription factor docking. Science (New York, N.Y.). 286: 1368-71. PMID 10558993 DOI: 10.1126/Science.286.5443.1368  0.88
1999 Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell. 98: 115-24. PMID 10412986 DOI: 10.1016/S0092-8674(00)80611-X  0.88
1999 Serra F, Bonet ML, Puigserver P, Oliver J, Palou A. Stimulation of uncoupling protein 1 expression in brown adipocytes by naturally occurring carotenoids. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 23: 650-5. PMID 10411240 DOI: 10.1038/Sj.Ijo.0800897  0.88
1998 Picó C, Puigserver P, Oliver P, Palou A. 2-Methoxyestradiol, an endogenous metabolite of 17beta-estradiol, inhibits adipocyte proliferation. Molecular and Cellular Biochemistry. 189: 1-7. PMID 9879647 DOI: 10.1023/A:1006835124149  0.88
1998 Puigserver P, Ribot J, Serra F, Gianotti M, Bonet ML, Nadal-Ginard B, Palou A. Involvement of the retinoblastoma protein in brown and white adipocyte cell differentiation: functional and physical association with the adipogenic transcription factor C/EBPalpha. European Journal of Cell Biology. 77: 117-23. PMID 9840461 DOI: 10.1016/S0171-9335(98)80079-4  0.88
1998 Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 92: 829-39. PMID 9529258 DOI: 10.1016/S0092-8674(00)81410-5  0.88
1997 Garcia-Palmer FJ, Pericas J, Matamala JC, Puigserver P, Bonet ML, Palou A, Gianotti M. Diminished response to food deprivation of the rat brown adipose tissue mitochondrial uncoupling system with age. Biochemistry and Molecular Biology International. 42: 1151-61. PMID 9305533 DOI: 10.1080/15216549700203621  0.88
1997 Bonet ML, Puigserver P, Serra F, Ribot J, Vázquez F, Pico C, Palou A. Retinoic acid modulates retinoid X receptor alpha and retinoic acid receptor alpha levels of cultured brown adipocytes. Febs Letters. 406: 196-200. PMID 9109417 DOI: 10.1016/S0014-5793(97)00274-3  0.88
1996 Puigserver P, Vázquez F, Bonet ML, Picó C, Palou A. In vitro and in vivo induction of brown adipocyte uncoupling protein (thermogenin) by retinoic acid. The Biochemical Journal. 317: 827-33. PMID 8760369 DOI: 10.1042/Bj3170827  0.88
1996 Puigserver P, Picó C, Stock MJ, Palou A. Effect of selective beta-adrenoceptor stimulation on UCP synthesis in primary cultures of brown adipocytes. Molecular and Cellular Endocrinology. 117: 7-16. PMID 8734469 DOI: 10.1016/0303-7207(95)03727-6  0.88
1996 Herron D, Mariga S, Puigserver P, Cannon B, Nedergaard J. Effect of short- and long-term adrenergic stimulation on the expression of the uncoupling protein thermogenin (UCP) in brown adipocyte precursor cells differentiating in culture Biochemical Society Transactions. 24: 550S.  0.88
1994 Moreno M, Puigserver P, Llull J, Gianotti M, Lanni A, Goglia F, Palou A. Cold exposure induces different uncoupling-protein thermogenin masking/unmasking processes in brown adipose tissue depending on mitochondrial subtypes. The Biochemical Journal. 300: 463-8. PMID 8002952 DOI: 10.1042/Bj3000463  0.88
1992 Puigserver P, Herron D, Gianotti M, Palou A, Cannon B, Nedergaard J. Induction and degradation of the uncoupling protein thermogenin in brown adipocytes in vitro and in vivo. Evidence for a rapidly degradable pool. The Biochemical Journal. 284: 393-8. PMID 1599423 DOI: 10.1042/Bj2840393  0.88
1992 Puigserver P, Palou A, Gianotti M. Dietary regulation of fasting-induced mitochondrial protein degradation in adult rat brown adipose tissue. Biochemistry International. 27: 1037-46. PMID 1332718  0.88
1992 Puigserver P, Gianotti M, Palou A. Impaired starvation-induced loss of mitochondrial protein in the brown adipose tissue of dietary obese rats. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 16: 255-61. PMID 1318279  0.88
1991 Puigserver P, Lladó I, Palou A, Gianotti M. Evidence for masking of brown adipose tissue mitochondrial GDP-binding sites in response to fasting in rats made obese by dietary manipulation. Effects of reversion to standard diet. The Biochemical Journal. 279: 575-9. PMID 1953651 DOI: 10.1042/Bj2790575  0.88
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