Kalipada Pahan - Publications

Affiliations: 
Rush University Medical Center, Chicago, IL, United States 

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Raha S, Dutta D, Roy A, Pahan K. Reduction of Lewy Body Pathology by Oral Cinnamon. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 32889602 DOI: 10.1007/S11481-020-09955-2  0.323
2020 Patel DR, Roy A, Raha S, Kundu M, Gonzalez F, Pahan K. Upregulation of BDNF and hippocampal functions by a hippocampal ligand of PPARα. Jci Insight. PMID 32315292 DOI: 10.1172/Jci.Insight.136654  0.312
2020 Rangasamy SB, Ghosh S, Pahan K. RNS60, a physically-modified saline, inhibits glial activation, suppresses neuronal apoptosis and protects memory in a mouse model of traumatic brain injury. Experimental Neurology. 328: 113279. PMID 32151546 DOI: 10.1016/J.Expneurol.2020.113279  0.354
2019 Patel D, Roy A, Pahan K. PPARα serves as a new receptor of aspirin for neuroprotection. Journal of Neuroscience Research. PMID 31797405 DOI: 10.1002/Jnr.24561  0.339
2019 Pahan K. A Broad Application of CRISPR Cas9 in Infectious, Inflammatory and Neurodegenerative Diseases. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 14: 534-536. PMID 31782056 DOI: 10.1007/S11481-019-09889-4  0.324
2019 Drohomyrecky PC, Doroshenko ER, Akkermann R, Moshkova M, Yi TJ, Zhao FL, Ahn JJ, McGaha TL, Pahan K, Dunn SE. Peroxisome Proliferator-Activated Receptor-δ Acts within Peripheral Myeloid Cells to Limit Th Cell Priming during Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 31578267 DOI: 10.4049/Jimmunol.1801200  0.347
2019 Dutta D, Kundu M, Mondal S, Roy A, Ruehl S, Hall DA, Pahan K. RANTES-induced invasion of Th17 cells into substantia nigra potentiates dopaminergic cell loss in MPTP mouse model of Parkinson's disease. Neurobiology of Disease. 104575. PMID 31445159 DOI: 10.1016/J.Nbd.2019.104575  0.347
2019 Chandra S, Roy A, Patel DR, Pahan K. PPARα Between Aspirin and Plaque Clearance. Journal of Alzheimer's Disease : Jad. PMID 31424405 DOI: 10.3233/Jad-190586  0.311
2019 Chakrabarti S, Roy A, Prorok T, Patel D, Dasarathi S, Pahan K. Aspirin upregulates Suppressor of Cytokine Signaling 3 in glial cells via PPARα. Journal of Neurochemistry. PMID 31273781 DOI: 10.1111/Jnc.14813  0.393
2019 Pahan S, Pahan K. Mode of Action of Aspirin in Experimental Autoimmune Encephalomyelitis. Dna and Cell Biology. PMID 31140860 DOI: 10.1089/Dna.2019.4814  0.358
2019 Gottschalk CG, Roy A, Jana M, Kundu M, Pahan K. Activation of Peroxisome Proliferator-Activated Receptor-α Increases the Expression of Nuclear Receptor Related 1 Protein (Nurr1) in Dopaminergic Neurons. Molecular Neurobiology. PMID 31127527 DOI: 10.1007/S12035-019-01649-Y  0.371
2019 Patel D, Jana A, Roy A, Pahan K. Cinnamon and its Metabolite Protect the Nigrostriatum in a Mouse Model of Parkinson's Disease Via Astrocytic GDNF. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 31119595 DOI: 10.1007/S11481-019-09855-0  0.382
2019 Mondal S, Rangasamy SB, Roy A, Dasarathy S, Kordower JH, Pahan K. Low-Dose Maraviroc, an Antiretroviral Drug, Attenuates the Infiltration of T Cells into the Central Nervous System and Protects the Nigrostriatum in Hemiparkinsonian Monkeys. Journal of Immunology (Baltimore, Md. : 1950). PMID 31043478 DOI: 10.4049/Jimmunol.1800587  0.317
2019 Chakrabarti S, Chandra S, Roy A, Dasarathi S, Kundu M, Pahan K. Upregulation of tripeptidyl-peptidase 1 by 3-hydroxy-(2,2)-dimethyl butyrate, a brain endogenous ligand of PPARα: Implications for late-infantile Batten disease therapy. Neurobiology of Disease. PMID 30928643 DOI: 10.1016/J.Nbd.2019.03.025  0.376
2019 Prorok T, Jana M, Patel D, Pahan K. Cinnamic Acid Protects the Nigrostriatum in a Mouse Model of Parkinson's Disease via Peroxisome Proliferator-Activated Receptorα. Neurochemical Research. PMID 30612307 DOI: 10.1007/S11064-018-02705-0  0.324
2018 Dodiya HB, Forsyth CB, Voigt RM, Engen PA, Patel J, Shaikh M, Green SJ, Naqib A, Roy A, Kordower JH, Pahan K, Shannon KM, Keshavarzian A. Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease. Neurobiology of Disease. PMID 30579705 DOI: 10.1016/J.Nbd.2018.12.012  0.333
2018 Chandra S, Roy A, Jana M, Pahan K. Cinnamic acid activates PPARα to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model. Neurobiology of Disease. 124: 379-395. PMID 30578827 DOI: 10.1016/J.Nbd.2018.12.007  0.346
2018 Mondal S, Jana M, Dasarathi S, Roy A, Pahan K. Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11-mediated protection of regulatory T cells. Science Signaling. 11. PMID 30482850 DOI: 10.1126/Scisignal.Aar8278  0.32
2018 Rangasamy SB, Dasarathi S, Pahan P, Jana M, Pahan K. Low-Dose Aspirin Upregulates Tyrosine Hydroxylase and Increases Dopamine Production in Dopaminergic Neurons: Implications for Parkinson's Disease. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 30187283 DOI: 10.1007/S11481-018-9808-3  0.352
2018 Rangasamy SB, Jana M, Roy A, Corbett GT, Kundu M, Chandra S, Mondal S, Dasarathi S, Mufson EJ, Mishra RK, Luan CH, Bennett DA, Pahan K. Selective disruption of TLR2/MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology. The Journal of Clinical Investigation. PMID 29990310 DOI: 10.1172/Jci96209  0.333
2018 Chandra S, Jana M, Pahan K. Aspirin induces Lysosomal biogenesis and attenuates Amyloid plaque pathology in a mouse model of Alzheimer's disease via PPARα. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29967008 DOI: 10.1523/Jneurosci.0054-18.2018  0.354
2018 Chakrabarti S, Jana M, Roy A, Pahan K. Upregulation of suppressor of cytokine signaling 3 in microglia by cinnamic acid. Current Alzheimer Research. PMID 29732971 DOI: 10.2174/1567205015666180507104755  0.386
2017 Chandra G, Kundu M, Rangasamy SB, Dasarathy S, Ghosh S, Watson R, Pahan K. Increase in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1α. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 29188424 DOI: 10.1007/S11481-017-9771-4  0.313
2017 Jana M, Ghosh S, Pahan K. Upregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis. Neurochemical Research. PMID 29143164 DOI: 10.1007/S11064-017-2435-1  0.347
2017 Kundu M, Roy A, Pahan K. Selective neutralization of IL-12 p40 monomer induces death in prostate cancer cells via IL-12-IFN-γ. Proceedings of the National Academy of Sciences of the United States of America. 114: 11482-11487. PMID 29073075 DOI: 10.1073/Pnas.1705536114  0.301
2017 Chandra G, Roy A, Rangasamy SB, Pahan K. Induction of Adaptive Immunity Leads to Nigrostriatal Disease Progression in MPTP Mouse Model of Parkinson's Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 28446566 DOI: 10.4049/Jimmunol.1700149  0.352
2017 Mondal S, Dasarathi S, Pahan K. Glyceryl Tribenzoate: A Flavoring Ingredient, Inhibits the Adoptive Transfer of Experimental Allergic Encephalomyelitis via TGF-β: Implications for Multiple Sclerosis Therapy. Journal of Clinical & Cellular Immunology. 8. PMID 28367355 DOI: 10.4172/2155-9899.1000488  0.301
2017 Mondal S, Rangasamy SB, Ghosh S, Watson RL, Pahan K. Nebulization of RNS60, a Physically-Modified Saline, Attenuates the Adoptive Transfer of Experimental Allergic Encephalomyelitis in Mice: Implications for Multiple Sclerosis Therapy. Neurochemical Research. PMID 28271325 DOI: 10.1007/S11064-017-2214-Z  0.311
2017 Ghosh A, Rangasamy SB, Modi KK, Pahan K. Gemfibrozil, Food and Drug Administration-approved lipid-lowering drug, increases longevity in mouse model of Late Infantile Neuronal Ceroid Lipofuscinosis. Journal of Neurochemistry. PMID 28199020 DOI: 10.1111/Jnc.13987  0.373
2016 Roy A, Kundu M, Jana M, Mishra RK, Yung Y, Luan CH, Gonzalez FJ, Pahan K. Identification and characterization of PPARα ligands in the hippocampus. Nature Chemical Biology. PMID 27748752 DOI: 10.1038/Nchembio.2204  0.305
2016 Chandra G, Rangasamy SB, Roy A, Kordower JH, Pahan K. Neutralization of regulated on activation, normal T cell expressed and secreted and eotaxin prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease. The Journal of Biological Chemistry. PMID 27226559 DOI: 10.1074/Jbc.M116.714824  0.362
2016 Roy A, Rangasamy SB, Kundu M, Pahan K. BPOZ-2 Gene Delivery Ameliorates Alpha-Synucleinopathy in A53T Transgenic Mouse Model of Parkinson's Disease. Scientific Reports. 6: 22067. PMID 26916519 DOI: 10.1038/Srep22067  0.351
2015 Rangasamy SB, Corbett GT, Roy A, Modi KK, Bennett DA, Mufson EJ, Ghosh S, Pahan K. Intranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 47: 385-402. PMID 26401561 DOI: 10.3233/Jad-150040  0.35
2015 Modi KK, Jana M, Mondal S, Pahan K. Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes. Neurochemical Research. 40: 2333-47. PMID 26399250 DOI: 10.1007/S11064-015-1723-X  0.386
2015 Pahan K. Prospects of Cinnamon in Multiple Sclerosis. Journal of Multiple Sclerosis. 2: 1000149. PMID 26380380 DOI: 10.4172/2376-0389.1000149  0.324
2015 Roy A, Jana M, Kundu M, Corbett GT, Rangaswamy SB, Mishra RK, Luan CH, Gonzalez FJ, Pahan K. HMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice. Cell Metabolism. PMID 26118928 DOI: 10.1016/J.Cmet.2015.05.022  0.335
2015 Modi KK, Roy A, Brahmachari S, Rangasamy SB, Pahan K. Cinnamon and Its Metabolite Sodium Benzoate Attenuate the Activation of p21rac and Protect Memory and Learning in an Animal Model of Alzheimer's Disease. Plos One. 10: e0130398. PMID 26102198 DOI: 10.1371/Journal.Pone.0130398  0.357
2015 Corbett GT, Gonzalez FJ, Pahan K. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP. Proceedings of the National Academy of Sciences of the United States of America. 112: 8445-50. PMID 26080426 DOI: 10.1073/Pnas.1504890112  0.337
2015 Roy A, Mondal S, Kordower JH, Pahan K. Attenuation of microglial RANTES by NEMO-binding domain peptide inhibits the infiltration of CD8(+) T cells in the nigra of hemiparkinsonian monkey. Neuroscience. PMID 25783477 DOI: 10.1016/J.Neuroscience.2015.03.011  0.4
2015 Ghosh A, Jana M, Modi K, Gonzalez FJ, Sims KB, Berry-Kravis E, Pahan K. Activation of peroxisome proliferator-activated receptor α induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders. The Journal of Biological Chemistry. 290: 10309-24. PMID 25750174 DOI: 10.1074/Jbc.M114.610659  0.361
2015 Mondal S, Pahan K. Cinnamon ameliorates experimental allergic encephalomyelitis in mice via regulatory T cells: implications for multiple sclerosis therapy. Plos One. 10: e0116566. PMID 25569428 DOI: 10.1371/Journal.Pone.0116566  0.33
2014 Modi KK, Jana A, Ghosh S, Watson R, Pahan K. A physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of Alzheimer's disease. Plos One. 9: e103606. PMID 25089827 DOI: 10.1371/Journal.Pone.0103606  0.347
2014 Roy A, Modi KK, Khasnavis S, Ghosh S, Watson R, Pahan K. Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase. Plos One. 9: e101883. PMID 25007337 DOI: 10.1371/Journal.Pone.0101883  0.305
2014 Khasnavis S, Pahan K. Cinnamon treatment upregulates neuroprotective proteins Parkin and DJ-1 and protects dopaminergic neurons in a mouse model of Parkinson's disease. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 569-81. PMID 24946862 DOI: 10.1007/S11481-014-9552-2  0.388
2014 Khasnavis S, Roy A, Ghosh S, Watson R, Pahan K. Protection of dopaminergic neurons in a mouse model of Parkinson's disease by a physically-modified saline containing charge-stabilized nanobubbles. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 218-32. PMID 24122363 DOI: 10.1007/S11481-013-9503-3  0.397
2013 Roy A, Pahan K. Myelin Basic Protein-primed T Helper 2 Cells Suppress Microglial Activation via AlphaVBeta3 Integrin: Implications for Multiple Sclerosis. Journal of Clinical & Cellular Immunology. 7: 158. PMID 24575330 DOI: 10.4172/2155-9899.1000158  0.372
2013 Jana M, Pahan K. Down-regulation of Myelin Gene Expression in Human Oligodendrocytes by Nitric Oxide: Implications for Demyelination in Multiple Sclerosis. Journal of Clinical & Cellular Immunology. 4. PMID 24273691 DOI: 10.4172/2155-9899.1000157  0.356
2013 Roy A, Pahan K. Ankyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: implications for Parkinson's disease. Febs Letters. 587: 3567-74. PMID 24076025 DOI: 10.1016/J.Febslet.2013.09.020  0.35
2013 Khasnavis S, Ghosh A, Roy A, Pahan K. Castration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase. The Journal of Biological Chemistry. 288: 20843-55. PMID 23744073 DOI: 10.1074/Jbc.M112.443556  0.344
2013 Modi KK, Sendtner M, Pahan K. Up-regulation of ciliary neurotrophic factor in astrocytes by aspirin: implications for remyelination in multiple sclerosis. The Journal of Biological Chemistry. 288: 18533-45. PMID 23653362 DOI: 10.1074/Jbc.M112.447268  0.395
2013 Jana A, Modi KK, Roy A, Anderson JA, van Breemen RB, Pahan K. Up-regulation of neurotrophic factors by cinnamon and its metabolite sodium benzoate: therapeutic implications for neurodegenerative disorders. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 739-55. PMID 23475543 DOI: 10.1007/S11481-013-9447-7  0.369
2013 Corbett GT, Roy A, Pahan K. Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy. The Journal of Biological Chemistry. 288: 8299-312. PMID 23404502 DOI: 10.1074/Jbc.M112.426536  0.367
2013 Miller NM, Shriver LP, Bodiga VL, Ray A, Basu S, Ahuja R, Jana A, Pahan K, Dittel BN. Lymphocytes with cytotoxic activity induce rapid microtubule axonal destabilization independently and before signs of neuronal death. Asn Neuro. 5: e00105. PMID 23289514 DOI: 10.1042/An20120087  0.355
2013 Ghosh A, Corbett G, Gonzalez F, Pahan K. Activation of PPAR-a:RXRa pathway upregulates tripeptidyl peptidase 1 in brain cells: Implications for late infantile neuronal ceroid lipofuscinosis therapy Molecular Genetics and Metabolism. 108: S42-S43. DOI: 10.1016/J.Ymgme.2012.11.094  0.338
2012 Pahan K, Mondal S. Crosstalk between Nitric Oxide and T helper cells. Journal of Clinical & Cellular Immunology. 3. PMID 23336087 DOI: 10.4172/2155-9899.1000E109  0.349
2012 Mondal S, Martinson JA, Ghosh S, Watson R, Pahan K. Protection of Tregs, suppression of Th1 and Th17 cells, and amelioration of experimental allergic encephalomyelitis by a physically-modified saline. Plos One. 7: e51869. PMID 23284794 DOI: 10.1371/Journal.Pone.0051869  0.333
2012 Mondal S, Brahmachari S, Pahan K. Regulation of encephalitogenicity of neuroantigen-primed T cells by nitric oxide: Implications for multiple sclerosis. Journal of Clinical & Cellular Immunology. 3: 124. PMID 23275862 DOI: 10.4172/2165-8048.1000124  0.32
2012 Ghosh A, Corbett GT, Gonzalez FJ, Pahan K. Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor α: implications for late infantile Batten disease therapy. The Journal of Biological Chemistry. 287: 38922-35. PMID 22989886 DOI: 10.1074/Jbc.M112.365148  0.382
2012 Jana M, Mondal S, Gonzalez FJ, Pahan K. Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-β. The Journal of Biological Chemistry. 287: 34134-48. PMID 22879602 DOI: 10.1074/Jbc.M112.398552  0.333
2012 Khasnavis S, Jana A, Roy A, Mazumder M, Bhushan B, Wood T, Ghosh S, Watson R, Pahan K. Suppression of nuclear factor-κB activation and inflammation in microglia by physically modified saline. The Journal of Biological Chemistry. 287: 29529-42. PMID 22753407 DOI: 10.1074/Jbc.M111.338012  0.373
2012 Roy A, Ghosh A, Jana A, Liu X, Brahmachari S, Gendelman HE, Pahan K. Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease. Plos One. 7: e38113. PMID 22723850 DOI: 10.1371/Journal.Pone.0038113  0.415
2012 Corbett GT, Roy A, Pahan K. Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense. Journal of Immunology (Baltimore, Md. : 1950). 189: 1002-13. PMID 22706077 DOI: 10.4049/Jimmunol.1102624  0.331
2012 Ghosh A, Pahan K. Gemfibrozil, a lipid-lowering drug, induces suppressor of cytokine signaling 3 in glial cells: implications for neurodegenerative disorders. The Journal of Biological Chemistry. 287: 27189-203. PMID 22685291 DOI: 10.1074/Jbc.M112.346932  0.405
2012 Mondal S, Roy A, Jana A, Ghosh S, Kordower JH, Pahan K. Testing NF-κB-based therapy in hemiparkinsonian monkeys. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 544-56. PMID 22661311 DOI: 10.1007/S11481-012-9377-9  0.311
2012 Jana M, Pahan K. Gemfibrozil, a lipid lowering drug, inhibits the activation of primary human microglia via peroxisome proliferator-activated receptor β. Neurochemical Research. 37: 1718-29. PMID 22528839 DOI: 10.1007/S11064-012-0781-6  0.394
2012 Khasnavis S, Pahan K. Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 424-35. PMID 21701815 DOI: 10.1007/S11481-011-9286-3  0.402
2012 Khasnavis S, Jana A, Roy A, Wood T, Ghosh S, Watson R, Pahan K. Suppression of NF- B Activation and Inflammation in Glial Cells by RNS60, a Novel Therapeutic: Implications for Neurodegenerative Disorders (PD4.001) Neurology. 78: PD4.001-PD4.001. DOI: 10.1212/Wnl.78.1_Meetingabstracts.Pd4.001  0.323
2012 Mondal S, Ghosh S, Watson R, Pahan K. RNS60, a Novel Therapeutic, Modifies T-Helper Cells and Inhibits Experimental Allergic Encephalomyelitis: Implications for Treating Multiple Sclerosis (P05.116) Neurology. 78: P05.116-P05.116. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P05.116  0.342
2011 Pahan K. Immunomodulation of experimental allergic encephalomyelitis by cinnamon metabolite sodium benzoate. Immunopharmacology and Immunotoxicology. 33: 586-93. PMID 21425926 DOI: 10.3109/08923973.2011.561861  0.346
2010 Jana A, Pahan K. Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12676-89. PMID 20861373 DOI: 10.1523/Jneurosci.1243-10.2010  0.382
2010 Jana A, Pahan K. Sphingolipids in multiple sclerosis. Neuromolecular Medicine. 12: 351-61. PMID 20607622 DOI: 10.1007/S12017-010-8128-4  0.345
2010 Brahmachari S, Pahan K. Gender-specific expression of beta1 integrin of VLA-4 in myelin basic protein-primed T cells: implications for gender bias in multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 184: 6103-13. PMID 20483780 DOI: 10.4049/Jimmunol.0804356  0.312
2010 Brahmachari S, Pahan K. Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide. Journal of Immunology (Baltimore, Md. : 1950). 184: 1799-809. PMID 20083653 DOI: 10.4049/Jimmunol.0804394  0.342
2009 Ghosh A, Roy A, Matras J, Brahmachari S, Gendelman HE, Pahan K. Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13543-56. PMID 19864567 DOI: 10.1523/Jneurosci.4144-09.2009  0.4
2009 Brahmachari S, Jana A, Pahan K. Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses. Journal of Immunology (Baltimore, Md. : 1950). 183: 5917-27. PMID 19812204 DOI: 10.4049/Jimmunol.0803336  0.42
2009 Roy A, Pahan K. Gemfibrozil, stretching arms beyond lipid lowering. Immunopharmacology and Immunotoxicology. 31: 339-51. PMID 19694602 DOI: 10.1080/08923970902785253  0.32
2009 Saha RN, Ghosh A, Palencia CA, Fung YK, Dudek SM, Pahan K. TNF-alpha preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein. Journal of Immunology (Baltimore, Md. : 1950). 183: 2068-78. PMID 19596989 DOI: 10.4049/Jimmunol.0801892  0.714
2009 Brahmachari S, Pahan K. Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide. Journal of Immunology (Baltimore, Md. : 1950). 183: 2045-58. PMID 19587012 DOI: 10.4049/Jimmunol.0800276  0.351
2009 Mondal S, Roy A, Pahan K. Functional blocking monoclonal antibodies against IL-12p40 homodimer inhibit adoptive transfer of experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 182: 5013-23. PMID 19342681 DOI: 10.4049/Jimmunol.0801734  0.343
2009 Jana M, Dasgupta S, Pal U, Pahan K. IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1. Glia. 57: 1553-65. PMID 19306359 DOI: 10.1002/Glia.20869  0.32
2009 Jana A, Hogan EL, Pahan K. Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death. Journal of the Neurological Sciences. 278: 5-15. PMID 19147160 DOI: 10.1016/J.Jns.2008.12.010  0.385
2009 Jana M, Pahan K. IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages. Molecular Immunology. 46: 773-83. PMID 19100623 DOI: 10.1016/J.Molimm.2008.10.033  0.308
2009 Jana M, Pahan K. Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70. Immunology. 127: 312-25. PMID 19019087 DOI: 10.1111/J.1365-2567.2008.02985.X  0.363
2009 Saha RN, Ghosh A, Palencia CA, Fung YK, Dudek SM, Pahan K. TNF-α preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein (Journal of Immunology (2009) 183, (2068-2078)) Journal of Immunology. 183: 6030. DOI: 10.4049/jimmunol.0990087  0.677
2008 Jana M, Palencia CA, Pahan K. Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease. Journal of Immunology (Baltimore, Md. : 1950). 181: 7254-62. PMID 18981147 DOI: 10.4049/Jimmunol.181.10.7254  0.354
2008 Roy A, Jana A, Yatish K, Freidt MB, Fung YK, Martinson JA, Pahan K. Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases. Free Radical Biology & Medicine. 45: 686-99. PMID 18590811 DOI: 10.1016/J.Freeradbiomed.2008.05.026  0.381
2008 Dasgupta S, Bandopadhyay M, Pahan K. Generation of functional blocking monoclonal antibodies against mouse interleukin-12 p40 homodimer and monomer. Hybridoma (2005). 27: 141-51. PMID 18582206 DOI: 10.1089/Hyb.2007.0560  0.309
2008 Auch CJ, Dasgupta S, Jana M, Liu X, Pahan K. Double-stranded RNA induces nitric oxide synthase in human astrocytes Journal of Neurochemistry. 81: 54-56. DOI: 10.1046/J.1471-4159.81.S1.18_5.X  0.361
2008 Pahan K, Jana M, Dasgupta S, Liu X. Induction of nitric oxide synthase in cytokine-stimulated human astrocytes by interleukin-12 P40 monomer Journal of Neurochemistry. 81: 54-56. DOI: 10.1046/J.1471-4159.81.S1.18_4.X  0.332
2008 Anderson JA, Jana M, Dasgupta S, Liu X, Pahan K. Involvement of P38MAP kinase in the induction of nitric oxide synthase in human astrocytes Journal of Neurochemistry. 81: 54-56. DOI: 10.1046/J.1471-4159.81.S1.18_3.X  0.413
2008 Dasgupta S, Jana M, Liu X, Pahan K. Induction of nitric oxide synthase in microglial cells by MBP-primed T cells Journal of Neurochemistry. 81: 54-56. DOI: 10.1046/J.1471-4159.81.S1.18_2.X  0.383
2008 Jana M, Dasgupta S, Liu X, Pahan K. Interleukin-12 P40 induces the expression of TNF-α in microglia and macrophages Journal of Neurochemistry. 81: 52-53. DOI: 10.1046/J.1471-4159.81.S1.17_1.X  0.38
2008 Jana A, Pahan K. P3-301: Amyloid-beta-activated glia kill human neurons via neutral sphingomyelinase Alzheimer's & Dementia. 4: T610-T610. DOI: 10.1016/J.Jalz.2008.05.1870  0.314
2008 Saha RN, Bidasee KR, Pahan K. CNS cell signaling Neuroimmune Pharmacology. 207-225. DOI: 10.1007/978-0-387-72573-4_16  0.546
2007 Jana A, Pahan K. Oxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 184-93. PMID 18040843 DOI: 10.1007/S11481-007-9066-2  0.315
2007 Ghosh A, Roy A, Liu X, Kordower JH, Mufson EJ, Hartley DM, Ghosh S, Mosley RL, Gendelman HE, Pahan K. Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 18754-9. PMID 18000063 DOI: 10.1073/Pnas.0704908104  0.355
2007 Saha RN, Jana M, Pahan K. MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65. Journal of Immunology (Baltimore, Md. : 1950). 179: 7101-9. PMID 17982102 DOI: 10.4049/Jimmunol.179.10.7101  0.629
2007 Roy A, Liu X, Pahan K. Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin. The Journal of Biological Chemistry. 282: 32222-32. PMID 17823123 DOI: 10.1074/Jbc.M702899200  0.387
2007 Jana M, Jana A, Liu X, Ghosh S, Pahan K. Involvement of phosphatidylinositol 3-kinase-mediated up-regulation of I kappa B alpha in anti-inflammatory effect of gemfibrozil in microglia. Journal of Immunology (Baltimore, Md. : 1950). 179: 4142-52. PMID 17785853 DOI: 10.4049/Jimmunol.179.6.4142  0.431
2007 Dasgupta S, Roy A, Jana M, Hartley DM, Pahan K. Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha. Molecular Pharmacology. 72: 934-46. PMID 17625103 DOI: 10.1124/Mol.106.033787  0.382
2007 Brahmachari S, Pahan K. Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 275-83. PMID 17579047 DOI: 10.4049/Jimmunol.179.1.275  0.335
2007 Saha RN, Pahan K. Differential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: Implications for HIV-associated dementia. Free Radical Biology & Medicine. 42: 1866-78. PMID 17512466 DOI: 10.1016/J.Freeradbiomed.2007.03.022  0.637
2007 Jana M, Jana A, Pal U, Pahan K. A simplified method for isolating highly purified neurons, oligodendrocytes, astrocytes, and microglia from the same human fetal brain tissue. Neurochemical Research. 32: 2015-22. PMID 17447141 DOI: 10.1007/S11064-007-9340-Y  0.364
2006 Saha RN, Liu X, Pahan K. Up-regulation of BDNF in astrocytes by TNF-alpha: a case for the neuroprotective role of cytokine. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 212-22. PMID 18040799 DOI: 10.1007/S11481-006-9020-8  0.647
2006 Saha RN, Pahan K. Regulation of inducible nitric oxide synthase gene in glial cells. Antioxidants & Redox Signaling. 8: 929-47. PMID 16771683 DOI: 10.1089/Ars.2006.8.929  0.666
2006 Saha RN, Pahan K. Signals for the induction of nitric oxide synthase in astrocytes. Neurochemistry International. 49: 154-63. PMID 16740341 DOI: 10.1016/J.Neuint.2006.04.007  0.637
2006 Brahmachari S, Fung YK, Pahan K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4930-9. PMID 16672668 DOI: 10.1523/Jneurosci.5480-05.2006  0.407
2006 Roy A, Fung YK, Liu X, Pahan K. Up-regulation of microglial CD11b expression by nitric oxide. The Journal of Biological Chemistry. 281: 14971-80. PMID 16551637 DOI: 10.1074/Jbc.M600236200  0.412
2006 Saha RN, Pahan K. HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis. Cell Death and Differentiation. 13: 539-50. PMID 16167067 DOI: 10.1038/Sj.Cdd.4401769  0.614
2005 Jana M, Pahan K. Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes. Free Radical Biology & Medicine. 39: 823-31. PMID 16109311 DOI: 10.1016/J.Freeradbiomed.2005.05.014  0.392
2005 Dasgupta S, Jana M, Liu X, Pahan K. Myelin basic protein-primed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: implications for gender bias in multiple sclerosis. The Journal of Biological Chemistry. 280: 32609-17. PMID 16046404 DOI: 10.1074/Jbc.M500299200  0.348
2005 Jana M, Anderson JA, Saha RN, Liu X, Pahan K. Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Radical Biology & Medicine. 38: 655-64. PMID 15683721 DOI: 10.1016/J.Freeradbiomed.2004.11.021  0.624
2004 Jana A, Pahan K. Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9531-40. PMID 15509740 DOI: 10.1523/Jneurosci.3085-04.2004  0.358
2004 Jana A, Pahan K. Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease. The Journal of Biological Chemistry. 279: 51451-9. PMID 15452132 DOI: 10.1074/Jbc.M404635200  0.355
2004 Dasgupta S, Jana M, Zhou Y, Fung YK, Ghosh S, Pahan K. Antineuroinflammatory effect of NF-kappaB essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 1344-54. PMID 15240729 DOI: 10.4049/Jimmunol.173.2.1344  0.325
2004 Auch CJ, Saha RN, Sheikh FG, Liu X, Jacobs BL, Pahan K. Role of protein kinase R in double-stranded RNA-induced expression of nitric oxide synthase in human astroglia. Febs Letters. 563: 223-8. PMID 15063753 DOI: 10.1016/S0014-5793(04)00302-3  0.65
2003 Saha RN, Pahan K. Tumor necrosis factor-alpha at the crossroads of neuronal life and death during HIV-associated dementia. Journal of Neurochemistry. 86: 1057-71. PMID 12911614 DOI: 10.1046/J.1471-4159.2003.01942.X  0.625
2003 Jana M, Dasgupta S, Saha RN, Liu X, Pahan K. Induction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophages. Journal of Neurochemistry. 86: 519-28. PMID 12871593 DOI: 10.1046/J.1471-4159.2003.01864.X  0.653
2003 Dasgupta S, Jana M, Liu X, Pahan K. Role of very-late antigen-4 (VLA-4) in myelin basic protein-primed T cell contact-induced expression of proinflammatory cytokines in microglial cells. The Journal of Biological Chemistry. 278: 22424-31. PMID 12690109 DOI: 10.1074/Jbc.M301789200  0.401
2003 Dasgupta S, Zhou Y, Jana M, Banik NL, Pahan K. Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps. Journal of Immunology (Baltimore, Md. : 1950). 170: 3874-82. PMID 12646656 DOI: 10.4049/Jimmunol.170.7.3874  0.369
2002 Pahan K, Jana M, Liu X, Taylor BS, Wood C, Fischer SM. Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes. The Journal of Biological Chemistry. 277: 45984-91. PMID 12244038 DOI: 10.1074/Jbc.M200250200  0.427
2002 Dasgupta S, Jana M, Liu X, Pahan K. Myelin basic protein-primed T cells induce nitric oxide synthase in microglial cells. Implications for multiple sclerosis. The Journal of Biological Chemistry. 277: 39327-33. PMID 12176974 DOI: 10.1074/Jbc.M111841200  0.353
2002 Liu X, Jana M, Dasgupta S, Koka S, He J, Wood C, Pahan K. Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia. The Journal of Biological Chemistry. 277: 39312-9. PMID 12167619 DOI: 10.1074/Jbc.M205107200  0.381
2002 Jana M, Dasgupta S, Liu X, Pahan K. Regulation of tumor necrosis factor-alpha expression by CD40 ligation in BV-2 microglial cells. Journal of Neurochemistry. 80: 197-206. PMID 11796758 DOI: 10.1046/J.0022-3042.2001.00691.X  0.337
2001 Jana M, Liu X, Koka S, Ghosh S, Petro TM, Pahan K. Ligation of CD40 stimulates the induction of nitric-oxide synthase in microglial cells. The Journal of Biological Chemistry. 276: 44527-33. PMID 11551948 DOI: 10.1074/Jbc.M106771200  0.322
2001 Pahan K, Sheikh FG, Liu X, Hilger S, McKinney M, Petro TM. Induction of nitric-oxide synthase and activation of NF-kappaB by interleukin-12 p40 in microglial cells. The Journal of Biological Chemistry. 276: 7899-905. PMID 11110796 DOI: 10.1074/Jbc.M008262200  0.394
2000 Pahan K, Khan M, Singh I. Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase. Journal of Neurochemistry. 75: 576-82. PMID 10899932 DOI: 10.1046/J.1471-4159.2000.0750576.X  0.318
2000 Pahan K, Schmid M. Activation of nuclear factor-kB in the spinal cord of experimental allergic encephalomyelitis. Neuroscience Letters. 287: 17-20. PMID 10841980 DOI: 10.1016/S0304-3940(00)01167-8  0.333
2000 Pahan K, Liu X, McKinney MJ, Wood C, Sheikh FG, Raymond JR. Expression of a dominant-negative mutant of p21(ras) inhibits induction of nitric oxide synthase and activation of nuclear factor-kappaB in primary astrocytes. Journal of Neurochemistry. 74: 2288-95. PMID 10820188 DOI: 10.1046/J.1471-4159.2000.0742288.X  0.349
2000 Pahan K, Liu X, Wood C, Raymond JR. Expression of a constitutively active form of phosphatidylinositol 3-kinase inhibits the induction of nitric oxide synthase in human astrocytes. Febs Letters. 472: 203-7. PMID 10788611 DOI: 10.1016/S0014-5793(00)01465-4  0.384
2000 Pahan K, Liu X. Expression of iNOS and activation of NF-kB in LPS- and cytokine-stimulated astrocytes involve the activation of p21Ras Biochemical Society Transactions. 28: A381-A381. DOI: 10.1042/Bst028A381B  0.357
1999 Stanislaus R, Pahan K, Singh AK, Singh I. Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin. Neuroscience Letters. 269: 71-4. PMID 10430507 DOI: 10.1016/S0304-3940(99)00414-0  0.387
1999 Pahan K, Dobashi K, Ghosh B, Singh I. Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide. Journal of Neurochemistry. 73: 513-20. PMID 10428046 DOI: 10.1046/J.1471-4159.1999.0730513.X  0.37
1999 Pahan K, Raymond JR, Singh I. Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells. The Journal of Biological Chemistry. 274: 7528-36. PMID 10066820 DOI: 10.1074/Jbc.274.11.7528  0.392
1998 Singh I, Pahan K, Khan M, Singh AK. Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases. The Journal of Biological Chemistry. 273: 20354-62. PMID 9685387 DOI: 10.1074/Jbc.273.32.20354  0.424
1998 Khan M, Pahan K, Singh AK, Singh I. Cytokine-induced accumulation of very long-chain fatty acids in rat C6 glial cells: implication for X-adrenoleukodystrophy. Journal of Neurochemistry. 71: 78-87. PMID 9648853 DOI: 10.1046/J.1471-4159.1998.71010078.X  0.384
1998 Pahan K, Sheikh FG, Namboodiri AM, Singh I. Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitric-oxide synthase in rat astrocytes and macrophages. The Journal of Biological Chemistry. 273: 12219-26. PMID 9575170 DOI: 10.1074/Jbc.273.20.12219  0.405
1998 Sheikh FG, Pahan K, Khan M, Barbosa E, Singh I. Abnormality in catalase import into peroxisomes leads to severe neurological disorder. Proceedings of the National Academy of Sciences of the United States of America. 95: 2961-6. PMID 9501198 DOI: 10.1073/Pnas.95.6.2961  0.317
1998 Pahan K, Sheikh FG, Khan M, Namboodiri AM, Singh I. Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes. The Journal of Biological Chemistry. 273: 2591-600. PMID 9446561 DOI: 10.1074/Jbc.273.5.2591  0.391
1998 Pahan K, Sheikh FG, Namboodiri AMS, Singh I. N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes Free Radical Biology and Medicine. 24: 39-48. PMID 9436612 DOI: 10.1016/S0891-5849(97)00137-8  0.405
1997 Pahan K, Sheikh FG, Namboodiri AM, Singh I. Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. The Journal of Clinical Investigation. 100: 2671-9. PMID 9389730 DOI: 10.1172/Jci119812  0.406
1997 Dobashi K, Pahan K, Chahal A, Singh I. Modulation of endogenous antioxidant enzymes by nitric oxide in rat C6 glial cells Journal of Neurochemistry. 68: 1896-1903. PMID 9109515 DOI: 10.1046/J.1471-4159.1997.68051896.X  0.376
1997 Pahan K, Namboodiri AMS, Sheikh FG, Smith BT, Singh I. Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes Journal of Biological Chemistry. 272: 7786-7791. PMID 9065441 DOI: 10.1074/Jbc.272.12.7786  0.404
1997 Dobashi K, Pahan K, Chahal A, Singh I. Modulation of Endogenous Antioxidant Enzymes by Nitric Oxide in Rat C6 Glial Cells † 1722 Pediatric Research. 41: 289-289. DOI: 10.1203/00006450-199704001-01741  0.378
1995 Kremser K, Stangl H, Pahan K, Singh I. Nitric oxide regulates peroxisomal enzyme activities. European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies. 33: 763-74. PMID 8620052 DOI: 10.1515/Cclm.1995.33.11.763  0.301
1995 Pahan K, Khan M, Smith BT, Singh I. Ketoconazole and other imidazole derivatives are potent inhibitors of peroxisomal phytanic acid α-oxidation Febs Letters. 377: 213-216. PMID 8543053 DOI: 10.1016/0014-5793(95)01341-5  0.324
1993 Pahan K, Cofer J, Baliga P, Singh I. Identification of phytanoyl-CoA ligase as a distinct acyl-CoA ligase in peroxisomes from cultured human skin fibroblasts Febs Letters. 322: 101-104. PMID 8482375 DOI: 10.1016/0014-5793(93)81546-C  0.307
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