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Cynthia Guidos - Publications

Affiliations: 
University of Alberta, Edmonton, Canada 
 University of Toronto, Toronto, ON, Canada 
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Vanner RJ, Dobson SM, Gan OI, McLeod J, Schoof EM, Grandal I, Wintersinger JA, Garcia-Prat L, Hosseini M, Xie SZ, Jin L, Mbong N, Voisin V, Chan-Seng-Yue M, Kennedy JA, ... ... Guidos CJ, et al. Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target. Blood Cancer Discovery. 3: 16-31. PMID 35019858 DOI: 10.1158/2643-3230.BCD-20-0216  0.604
2021 Rajakumar SA, Grandal I, Minden MD, Hitzler JK, Guidos CJ, Danska JS. Targeted blockade of immune mechanisms inhibit B precursor acute lymphoblastic leukemia cell invasion of the central nervous system. Cell Reports. Medicine. 2: 100470. PMID 35028611 DOI: 10.1016/j.xcrm.2021.100470  0.608
2020 Rajakumar SA, Papp E, Lee KK, Grandal I, Merico D, Liu CC, Allo B, Zhang L, Grynpas MD, Minden MD, Hitzler JK, Guidos CJ, Danska JS. B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction. Science Translational Medicine. 12. PMID 32938796 DOI: 10.1126/Scitranslmed.Aba5942  0.595
2020 Dobson SM, Garcia-Prat L, Vanner RJ, Wintersinger J, Waanders E, Gu Z, McLeod J, Gan OI, Grandal I, Payne-Turner D, Edmonson MN, Ma X, Fan Y, Voisin V, Chan-Seng-Yue M, ... ... Guidos CJ, et al. Relapse fated latent diagnosis subclones in acute B lineage leukaemia are drug tolerant and possess distinct metabolic programs. Cancer Discovery. PMID 32086311 DOI: 10.1158/2159-8290.Cd-19-1059  0.57
2018 McKinnon T, Venier R, Yohe M, Sindiri S, Gryder BE, Shern JF, Kabaroff L, Dickson B, Schleicher K, Chouinard-Pelletier G, Menezes S, Gupta A, Zhang X, Guha R, Ferrer M, ... ... Guidos CJ, et al. Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma. Oncogene. PMID 29487419 DOI: 10.1038/S41388-017-0122-Y  0.305
2015 Tourlakis ME, Zhang S, Ball HL, Gandhi R, Liu H, Zhong J, Yuan JS, Guidos CJ, Durie PR, Rommens JM. In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency. Plos Genetics. 11: e1005288. PMID 26057580 DOI: 10.1371/journal.pgen.1005288  0.313
2014 Gedye CA, Hussain A, Paterson J, Smrke A, Saini H, Sirskyj D, Pereira K, Lobo N, Stewart J, Go C, Ho J, Medrano M, Hyatt E, Yuan J, Lauriault S, ... ... Guidos CJ, et al. Cell surface profiling using high-throughput flow cytometry: a platform for biomarker discovery and analysis of cellular heterogeneity. Plos One. 9: e105602. PMID 25170899 DOI: 10.1371/Journal.Pone.0105602  0.545
2014 Johnson RM, Papp E, Grandal I, Kowalski PE, Nutter L, Wong RC, Joseph-George AM, Danska JS, Guidos CJ. MuLV-related endogenous retroviral elements and Flt3 participate in aberrant end-joining events that promote B-cell leukemogenesis. Genes & Development. 28: 1179-90. PMID 24888589 DOI: 10.1101/Gad.240820.114  0.653
2014 Perova T, Grandal I, Nutter LM, Papp E, Matei IR, Beyene J, Kowalski PE, Hitzler JK, Minden MD, Guidos CJ, Danska JS. Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia. Science Translational Medicine. 6: 236ra62. PMID 24828076 DOI: 10.1126/Scitranslmed.3008661  0.617
2012 Ridges S, Heaton WL, Joshi D, Choi H, Eiring A, Batchelor L, Choudhry P, Manos EJ, Sofla H, Sanati A, Welborn S, Agarwal A, Spangrude GJ, Miles RR, Cox JE, ... ... Guidos CJ, et al. Zebrafish screen identifies novel compound with selective toxicity against leukemia. Blood. 119: 5621-31. PMID 22490804 DOI: 10.1182/Blood-2011-12-398818  0.606
2011 Yuan JS, Tan JB, Visan I, Matei IR, Urbanellis P, Xu K, Danska JS, Egan SE, Guidos CJ. Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors. Blood. 117: 1184-95. PMID 21097675 DOI: 10.1182/Blood-2010-07-296616  0.57
2009 Stanley P, Guidos CJ. Regulation of Notch signaling during T- and B-cell development by O-fucose glycans. Immunological Reviews. 230: 201-15. PMID 19594638 DOI: 10.1111/J.1600-065X.2009.00791.X  0.322
2009 Tan JB, Xu K, Cretegny K, Visan I, Yuan JS, Egan SE, Guidos CJ. Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches. Immunity. 30: 254-63. PMID 19217325 DOI: 10.1016/j.immuni.2008.12.016  0.349
2007 Curry JD, Schulz D, Guidos CJ, Danska JS, Nutter L, Nussenzweig A, Schlissel MS. Chromosomal reinsertion of broken RSS ends during T cell development. The Journal of Experimental Medicine. 204: 2293-303. PMID 17785508 DOI: 10.1084/Jem.20070583  0.59
2007 Matei IR, Gladdy RA, Nutter LM, Canty A, Guidos CJ, Danska JS. ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes. Blood. 109: 1887-96. PMID 17077325 DOI: 10.1182/Blood-2006-05-020917  0.609
2006 Gladdy RA, Nutter LM, Kunath T, Danska JS, Guidos CJ. p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc. Molecular Cancer Research : McR. 4: 311-8. PMID 16687486 DOI: 10.1158/1541-7786.Mcr-05-0258  0.581
2006 Matei IR, Guidos CJ, Danska JS. ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection. Immunological Reviews. 209: 142-58. PMID 16448540 DOI: 10.1111/J.0105-2896.2006.00361.X  0.609
2006 Visan I, Yuan JS, Tan JB, Cretegny K, Guidos CJ. Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions. Immunological Reviews. 209: 76-94. PMID 16448535 DOI: 10.1111/j.0105-2896.2006.00360.x  0.305
2005 Tan JB, Visan I, Yuan JS, Guidos CJ. Requirement for Notch1 signals at sequential early stages of intrathymic T cell development. Nature Immunology. 6: 671-9. PMID 15951812 DOI: 10.1038/ni1217  0.356
2003 Koch U, Yuan JS, Harper JA, Guidos CJ. Fine-tuning Notch1 activation by endocytosis and glycosylation. Seminars in Immunology. 15: 99-106. PMID 12681946  0.353
2003 Gladdy RA, Taylor MD, Williams CJ, Grandal I, Karaskova J, Squire JA, Rutka JT, Guidos CJ, Danska JS. The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice. Cancer Cell. 3: 37-50. PMID 12559174 DOI: 10.1016/S1535-6108(02)00236-2  0.619
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