| Year |
Citation |
Score |
| 2023 |
Harrill JA, Everett LJ, Haggard DE, Bundy JL, Willis CM, Shah I, Friedman KP, Basili D, Middleton A, Judson RS. Exploring the Effects of Experimental Parameters and Data Modeling Approaches on In Vitro Transcriptomic Point-of-Departure Estimates. Toxicology. 153694. PMID 38043774 DOI: 10.1016/j.tox.2023.153694 |
0.488 |
|
| 2023 |
Reardon AJF, Farmahin R, Williams A, Meier MJ, Addicks GC, Yauk CL, Matteo G, Atlas E, Harrill J, Everett LJ, Shah I, Judson R, Ramaiahgari S, Ferguson SS, Barton-Maclaren TS. From vision toward best practices: Evaluating transcriptomic points of departure for application in risk assessment using a uniform workflow. Frontiers in Toxicology. 5: 1194895. PMID 37288009 DOI: 10.3389/ftox.2023.1194895 |
0.434 |
|
| 2023 |
Aurisano N, Jolliet O, Chiu WA, Judson R, Jang S, Unnikrishnan A, Kosnik MB, Fantke P. Probabilistic Points of Departure and Reference Doses for Characterizing Human Noncancer and Developmental/Reproductive Effects for 10,145 Chemicals. Environmental Health Perspectives. 131: 37016. PMID 36989077 DOI: 10.1289/EHP11524 |
0.364 |
|
| 2022 |
Shah I, Bundy J, Chambers B, Everett LJ, Haggard D, Harrill J, Judson RS, Nyffeler J, Patlewicz G. Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities. Chemical Research in Toxicology. PMID 36301716 DOI: 10.1021/acs.chemrestox.2c00245 |
0.396 |
|
| 2022 |
Kapraun DF, Sfeir M, Pearce R, Davidson S, Lumen A, Dallmann A, Judson R, Wambaugh JF. Evaluation of a Rapid, Generic Human Gestational Dose Model. Reproductive Toxicology (Elmsford, N.Y.). PMID 36122840 DOI: 10.1016/j.reprotox.2022.09.004 |
0.374 |
|
| 2022 |
Nyffeler J, Willis C, Harris FR, Taylor LW, Judson R, Everett LJ, Harrill JA. Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example. Toxicology and Applied Pharmacology. 444: 116032. PMID 35483669 DOI: 10.1016/j.taap.2022.116032 |
0.473 |
|
| 2022 |
Bundy JL, Judson R, Williams AJ, Grulke C, Shah I, Everett LJ. Predicting molecular initiating events using chemical target annotations and gene expression. Biodata Mining. 15: 7. PMID 35246223 DOI: 10.1186/s13040-022-00292-z |
0.413 |
|
| 2022 |
Patlewicz G, Dean JL, Gibbons CF, Judson RS, Keshava N, Vegosen L, Martin TM, Pradeep P, Simha A, Warren SH, Gwinn MR, DeMarini DM. Integrating publicly available information to screen potential candidates for chemical prioritization under the Toxic Substances Control Act: A proof of concept case study using genotoxicity and carcinogenicity. Computational Toxicology (Amsterdam, Netherlands). 20: 1-100185. PMID 35128218 DOI: 10.1016/j.comtox.2021.100185 |
0.515 |
|
| 2021 |
Sheffield T, Brown J, Davidson S, Friedman KP, Judson R. tcplfit2: an R-language general purpose concentration-response modeling package. Bioinformatics (Oxford, England). PMID 34791027 DOI: 10.1093/bioinformatics/btab779 |
0.332 |
|
| 2021 |
Pradeep P, Judson R, DeMarini DM, Keshava N, Martin TM, Dean J, Gibbons CF, Simha A, Warren SH, Gwinn MR, Patlewicz G. Evaluation of Existing QSAR Models and Structural Alerts and Development of New Ensemble Models for Genotoxicity Using a Newly Compiled Experimental Dataset. Computational Toxicology (Amsterdam, Netherlands). 18. PMID 34504984 DOI: 10.1016/j.comtox.2021.100167 |
0.308 |
|
| 2021 |
Fantke P, Chiu WA, Aylward L, Judson R, Huang L, Jang S, Gouin T, Rhomberg L, Aurisano N, McKone T, Jolliet O. Exposure and Toxicity Characterization of Chemical Emissions and Chemicals in Products: Global Recommendations and Implementation in USEtox. The International Journal of Life Cycle Assessment. 26: 899-915. PMID 34140756 DOI: 10.1007/s11367-021-01889-y |
0.371 |
|
| 2021 |
Harrill JA, Everett LJ, Haggard DE, Sheffield T, Bundy J, Willis CM, Thomas RS, Shah I, Judson RS. High-Throughput Transcriptomics Platform for Screening Environmental Chemicals. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 33538836 DOI: 10.1093/toxsci/kfab009 |
0.57 |
|
| 2020 |
Pradeep P, Patlewicz G, Pearce R, Wambaugh J, Wetmore B, Judson R. Using Chemical Structure Information to Develop Predictive Models for Toxicokinetic Parameters to Inform High-throughput Risk-assessment. Computational Toxicology (Amsterdam, Netherlands). 16. PMID 34124416 DOI: 10.1016/j.comtox.2020.100136 |
0.396 |
|
| 2020 |
Pradeep P, Friedman KP, Judson R. Structure-based QSAR Models to Predict Repeat Dose Toxicity Points of Departure. Computational Toxicology (Amsterdam, Netherlands). 16. PMID 34017928 DOI: 10.1016/j.comtox.2020.100139 |
0.345 |
|
| 2020 |
Emara Y, Fantke P, Judson R, Chang X, Pradeep P, Lehmann A, Siegert MW, Finkbeiner M. Integrating endocrine-related health effects into comparative human toxicity characterization. The Science of the Total Environment. 762: 143874. PMID 33401053 DOI: 10.1016/j.scitotenv.2020.143874 |
0.32 |
|
| 2020 |
Richard AM, Huang R, Waidyanatha S, Shinn P, Collins BJ, Thillainadarajah I, Grulke CM, Williams AJ, Lougee RR, Judson RS, Houck KA, Shobair M, Yang C, Rathman JF, Yasgar A, et al. The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology. Chemical Research in Toxicology. PMID 33140634 DOI: 10.1021/acs.chemrestox.0c00264 |
0.432 |
|
| 2020 |
Nyffeler J, Haggard DE, Willis C, Setzer RW, Judson R, Paul-Friedman K, Everett LJ, Harrill JA. Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data. Slas Discovery : Advancing Life Sciences R & D. 2472555220950245. PMID 32862757 DOI: 10.1177/2472555220950245 |
0.378 |
|
| 2020 |
Judson R, Houck K, Paul Friedman K, Brown J, Browne P, Johnston PA, Close DA, Mansouri K, Kleinstreuer N. Selecting a minimal set of androgen receptor assays for screening chemicals. Regulatory Toxicology and Pharmacology : Rtp. 104764. PMID 32798611 DOI: 10.1016/j.yrtph.2020.104764 |
0.469 |
|
| 2020 |
Borrel A, Huang R, Sakamuru S, Xia M, Simeonov A, Mansouri K, Houck KA, Judson RS, Kleinstreuer NC. High-Throughput Screening to Predict Chemical-Assay Interference. Scientific Reports. 10: 3986. PMID 32132587 DOI: 10.1038/s41598-020-60747-3 |
0.471 |
|
| 2020 |
Mansouri K, Kleinstreuer N, Abdelaziz AM, Alberga D, Alves VM, Andersson PL, Andrade CH, Bai F, Balabin I, Ballabio D, Benfenati E, Bhhatarai B, Boyer S, Chen J, Consonni V, ... ... Judson RS, et al. CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity. Environmental Health Perspectives. 128: 27002. PMID 32074470 DOI: 10.1289/Ehp5580 |
0.399 |
|
| 2020 |
Zurlinden TJ, Saili KS, Rush N, Kothiya P, Judson RS, Houck KA, Hunter ES, Baker NC, Palmer JA, Thomas RS, Knudsen TB. Profiling the ToxCast library with a pluripotent human (H9) stem cell line-based biomarker assay for developmental toxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32073639 DOI: 10.1093/Toxsci/Kfaa014 |
0.483 |
|
| 2019 |
Harrill J, Shah I, Setzer RW, Haggard D, Auerbach S, Judson R, Thomas RS. Considerations for Strategic Use of High-Throughput Transcriptomics Chemical Screening Data in Regulatory Decisions. Current Opinion in Toxicology. 15: 64-75. PMID 31501805 DOI: 10.1016/J.Cotox.2019.05.004 |
0.581 |
|
| 2019 |
Baker NC, Sipes NS, Franzosa J, Belair DG, Abbott BD, Judson RS, Knudsen TB. Characterizing cleft palate toxicants using ToxCast data, chemical structure, and the biomedical literature. Birth Defects Research. PMID 31471948 DOI: 10.1002/Bdr2.1581 |
0.437 |
|
| 2019 |
Watford S, Edwards S, Angrish M, Judson RS, Friedman KP. Progress in data interoperability to support computational toxicology and chemical safety evaluation. Toxicology and Applied Pharmacology. 114707. PMID 31404555 DOI: 10.1016/J.Taap.2019.114707 |
0.358 |
|
| 2019 |
Webster F, Gagné M, Patlewicz G, Pradeep P, Trefiak N, Judson RS, Barton-Maclaren TS. Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study. Regulatory Toxicology and Pharmacology : Rtp. 106: 278-291. PMID 31121201 DOI: 10.1016/j.yrtph.2019.05.017 |
0.377 |
|
| 2019 |
Thomas RS, Bahadori T, Buckley TJ, Cowden J, Deisenroth C, Dionisio KL, Frithsen JB, Grulke CM, Gwinn MR, Harrill JA, Higuchi M, Houck KA, Hughes MF, Hunter ES, Isaacs KK, ... Judson RS, et al. The next generation blueprint of computational toxicology at the U.S. Environmental Protection Agency. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30835285 DOI: 10.1093/Toxsci/Kfz058 |
0.407 |
|
| 2018 |
Manganelli S, Roncaglioni A, Mansouri K, Judson RS, Benfenati E, Manganaro A, Ruiz P. Development, validation and integration of in silico models to identify androgen active chemicals. Chemosphere. 220: 204-215. PMID 30584954 DOI: 10.1016/j.chemosphere.2018.12.131 |
0.521 |
|
| 2018 |
Judson RS, Thomas RS, Baker N, Simha A, Howey XM, Marable C, Kleinstreuer NC, Houck KA. Workflow for defining reference chemicals for assessing performance of in vitro assays. Altex. PMID 30570668 DOI: 10.14573/altex.1809281 |
0.532 |
|
| 2018 |
Wetmore BA, Clewell RA, Cholewa B, Parks B, Pendse SN, Black MB, Mansouri K, Haider S, Berg EL, Judson RS, Houck KA, Martin M, Clewell HJ, Andersen ME, Thomas RS, et al. Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 30218698 DOI: 10.1016/J.Tiv.2018.09.006 |
0.415 |
|
| 2018 |
Watt ED, Judson RS. Uncertainty quantification in ToxCast high throughput screening. Plos One. 13: e0196963. PMID 30044784 DOI: 10.1371/Journal.Pone.0196963 |
0.333 |
|
| 2018 |
Mansouri K, Grulke CM, Judson RS, Williams AJ. OPERA models for predicting physicochemical properties and environmental fate endpoints. Journal of Cheminformatics. 10: 10. PMID 29520515 DOI: 10.1186/S13321-018-0263-1 |
0.333 |
|
| 2018 |
Mav D, Shah RR, Howard BE, Auerbach SS, Bushel PR, Collins JB, Gerhold DL, Judson RS, Karmaus AL, Maull EA, Mendrick DL, Merrick BA, Sipes NS, Svoboda D, Paules RS. A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics. Plos One. 13: e0191105. PMID 29462216 DOI: 10.1371/Journal.Pone.0191105 |
0.396 |
|
| 2017 |
Haggard DE, Karmaus AL, Martin MT, Judson RS, Setzer RW, Paul Friedman K. High-throughput H295R steroidogenesis assay: utility as an alternative and a statistical approach to characterize effects on steroidogenesis. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29216406 DOI: 10.1093/Toxsci/Kfx274 |
0.398 |
|
| 2017 |
Williams AJ, Grulke CM, Edwards J, McEachran AD, Mansouri K, Baker NC, Patlewicz G, Shah I, Wambaugh JF, Judson RS, Richard AM. The CompTox Chemistry Dashboard: a community data resource for environmental chemistry. Journal of Cheminformatics. 9: 61. PMID 29185060 DOI: 10.1186/S13321-017-0247-6 |
0.357 |
|
| 2017 |
Judson R, Houck K, Watt E, Thomas RS. On selecting a minimal set of in vitro assays to reliably determine estrogen agonist activity. Regulatory Toxicology and Pharmacology : Rtp. PMID 28993267 DOI: 10.1016/J.Yrtph.2017.09.022 |
0.452 |
|
| 2017 |
Browne P, Judson RS, Casey W, Kleinstreuer N, Thomas RS. Correction to Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model. Environmental Science & Technology. PMID 28767231 DOI: 10.1021/acs.est.7b03317 |
0.326 |
|
| 2017 |
Blackwell BR, Ankley GT, Corsi SR, De Cicco LA, Houck KA, Judson RS, Li S, Martin MT, Murphy E, Schroeder A, Smith E, Swintek J, Villeneuve DL. An "EAR" on environmental surveillance and monitoring: A case study on the use of exposure-activity ratios (EARs) to prioritize sites, chemicals, and bioactivities of concern in Great Lakes waters. Environmental Science & Technology. PMID 28671818 DOI: 10.1021/Acs.Est.7B01613 |
0.492 |
|
| 2017 |
Lynch C, Sakamuru S, Huang R, Stavreva DA, Varticovski L, Hager GL, Judson RS, Houck KA, Kleinstreuer NC, Casey W, Paules RS, Simeonov A, Xia M. Identifying Environmental Chemicals as Agonists of the Androgen Receptor by Using a Quantitative High-throughput Screening Platform. Toxicology. PMID 28478275 DOI: 10.1016/J.Tox.2017.05.001 |
0.328 |
|
| 2017 |
Malloy T, Zaunbrecher V, Beryt E, Judson R, Tice R, Allard P, Blake A, Cote I, Godwin H, Heine L, Kerzic P, Kostal J, Marchant G, McPartland J, Moran K, et al. Advancing alternatives analysis: The role of predictive toxicology in selecting safer chemical products and processes. Integrated Environmental Assessment and Management. PMID 28247928 DOI: 10.1002/Ieam.1923 |
0.32 |
|
| 2016 |
Bushnell PJ, Ward W, Morozova TV, Oshiro WM, Lin MT, Judson RS, Hester SD, McKee JM, Higuchi M. Genetic Targets of Acute Toluene Inhalation in Drosophila melanogaster. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28013218 DOI: 10.1093/toxsci/kfw243 |
0.351 |
|
| 2016 |
Zang Q, Mansouri K, Williams AJ, Judson RS, Allen DG, Casey WM, Kleinstreuer NC. In Silico Prediction of Physicochemical Properties of Environmental Chemicals Using Molecular Fingerprints and Machine Learning. Journal of Chemical Information and Modeling. PMID 28006899 DOI: 10.1021/acs.jcim.6b00625 |
0.316 |
|
| 2016 |
Kleinstreuer NC, Ceger P, Watt ED, Martin M, Houck K, Browne P, Thomas RS, Casey WM, Dix DJ, Allen D, Sakamuru S, Xia M, Huang R, Judson R. Development and Validation of a Computational Model for Androgen Receptor Activity. Chemical Research in Toxicology. PMID 27933809 DOI: 10.1021/Acs.Chemrestox.6B00347 |
0.484 |
|
| 2016 |
Filer DL, Kothiya P, Setzer RW, Judson RS, Martin MT. tcpl: The ToxCast Pipeline for High-Throughput Screening Data. Bioinformatics (Oxford, England). PMID 27797781 DOI: 10.1093/Bioinformatics/Btw680 |
0.398 |
|
| 2016 |
Hill T, Nelms MD, Edwards SW, Martin M, Judson R, Corton JC, Wood CE. Negative Predictors of Carcinogenicity for Environmental Chemicals. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27679563 DOI: 10.1093/Toxsci/Kfw195 |
0.37 |
|
| 2016 |
Richard AM, Judson RS, Houck KA, Grulke CM, Volarath P, Thillainadarajah I, Yang C, Rathman JF, Martin MT, Wambaugh JF, Knudsen TB, Kancherla J, Mansouri K, Patlewicz GY, Williams AJ, et al. The ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology. Chemical Research in Toxicology. PMID 27367298 DOI: 10.1021/Acs.Chemrestox.6B00135 |
0.559 |
|
| 2016 |
Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S, Wambaugh J, Setzer RW, Kothya P, Phuong J, Filer D, Smith D, Reif D, Rotroff D, et al. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27208079 DOI: 10.1093/Toxsci/Kfw092 |
0.422 |
|
| 2016 |
Shah I, Liu J, Judson RS, Thomas RS, Patlewicz G. Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information. Regulatory Toxicology and Pharmacology : Rtp. PMID 27174420 DOI: 10.1016/j.yrtph.2016.05.008 |
0.412 |
|
| 2016 |
Auerbach S, Filer D, Reif D, Walker V, Holloway AC, Schlezinger J, Srinivasan S, Svoboda D, Judson R, Bucher JR, Thayer KA. Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast High Throughput Data. Environmental Health Perspectives. PMID 26978842 DOI: 10.1289/Ehp.1510456 |
0.313 |
|
| 2016 |
Mansouri K, Abdelaziz A, Rybacka A, Roncaglioni A, Tropsha A, Varnek A, Zakharov A, Worth A, Richard AM, Grulke CM, Trisciuzzi D, Fourches D, Horvath D, Benfenati E, Muratov E, ... ... Judson RS, et al. CERAPP: Collaborative Estrogen Receptor Activity Prediction Project. Environmental Health Perspectives. PMID 26908244 DOI: 10.1289/Ehp.1510267 |
0.443 |
|
| 2016 |
Paul Friedman K, Watt ED, Hornung MW, Hedge JM, Judson RS, Crofton KM, Houck KA, Simmons SO. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors within the ToxCast Phase I and II Chemical Libraries. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26884060 DOI: 10.1093/Toxsci/Kfw034 |
0.488 |
|
| 2016 |
Ryan N, Chorley B, Tice RR, Judson R, Corton JC. Moving Toward Integrating Gene Expression Profiling Into High-Throughput Testing: A Gene Expression Biomarker Accurately Predicts Estrogen Receptor α Modulation in a Microarray Compendium. Toxicological Sciences : An Official Journal of the Society of Toxicology. 151: 88-103. PMID 26865669 DOI: 10.1093/toxsci/kfw026 |
0.405 |
|
| 2016 |
Rager JE, Strynar MJ, Liang S, McMahen RL, Richard AM, Grulke CM, Wambaugh JF, Isaacs KK, Judson R, Williams AJ, Sobus JR. Linking high resolution mass spectrometry data with exposure and toxicity forecasts to advance high-throughput environmental monitoring. Environment International. 88: 269-280. PMID 26812473 DOI: 10.1016/J.Envint.2015.12.008 |
0.423 |
|
| 2015 |
Dionisio KL, Frame AM, Goldsmith MR, Wambaugh JF, Liddell A, Cathey T, Smith D, Vail J, Ernstoff AS, Fantke P, Jolliet O, Judson RS. Exploring consumer exposure pathways and patterns of use for chemicals in the environment. Toxicology Reports. 2: 228-237. PMID 28962356 DOI: 10.1016/J.Toxrep.2014.12.009 |
0.468 |
|
| 2015 |
Leung MC, Phuong J, Baker NC, Sipes NS, Klinefelter GR, Martin MT, McLaurin KW, Setzer RW, Darney SP, Judson RS, Knudsen TB. Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes. Environmental Health Perspectives. PMID 26662846 DOI: 10.1289/Ehp.1510385 |
0.308 |
|
| 2015 |
Trisciuzzi D, Alberga D, Mansouri K, Judson R, Cellamare S, Catto M, Carotti A, Benfenati E, Novellino E, Mangiatordi GF, Nicolotti O. Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data. Future Medicinal Chemistry. 7: 1921-36. PMID 26440057 DOI: 10.4155/fmc.15.103 |
0.364 |
|
| 2015 |
Judson RS, Magpantay FM, Chickarmane V, Haskell C, Tania N, Taylor J, Xia M, Huang R, Rotroff DM, Filer DL, Houck KA, Martin MT, Sipes N, Richard AM, Mansouri K, et al. Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26272952 DOI: 10.1093/Toxsci/Kfv168 |
0.465 |
|
| 2015 |
Wetmore BA, Wambaugh JF, Allen B, Ferguson SS, Sochaski MA, Setzer RW, Houck KA, Strope CL, Cantwell K, Judson RS, LeCluyse E, Clewell HJ, Thomas RS, Andersen ME. Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26251325 DOI: 10.1093/toxsci/kfv171 |
0.441 |
|
| 2015 |
Wambaugh JF, Wetmore BA, Pearce R, Strope C, Goldsmith R, Sluka JP, Sedykh A, Tropsha A, Bosgra S, Shah I, Judson R, Thomas RS, Setzer RW. Toxicokinetic Triage for Environmental Chemicals. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26085347 DOI: 10.1093/toxsci/kfv118 |
0.464 |
|
| 2015 |
Browne P, Judson RS, Casey WM, Kleinstreuer NC, Thomas RS. Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model. Environmental Science & Technology. 49: 8804-14. PMID 26066997 DOI: 10.1021/acs.est.5b02641 |
0.467 |
|
| 2015 |
Berggren E, Amcoff P, Benigni R, Blackburn K, Carney E, Cronin M, Deluyker H, Gautier F, Judson RS, Kass GE, Keller D, Knight D, Lilienblum W, Mahony C, Rusyn I, et al. Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision Making. Environmental Health Perspectives. PMID 25956009 DOI: 10.1289/Ehp.1409342 |
0.309 |
|
| 2015 |
Liu J, Mansouri K, Judson RS, Martin MT, Hong H, Chen M, Xu X, Thomas RS, Shah I. Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structure. Chemical Research in Toxicology. 28: 738-51. PMID 25697799 DOI: 10.1021/Tx500501H |
0.369 |
|
| 2014 |
Wambaugh JF, Wang A, Dionisio KL, Frame A, Egeghy P, Judson R, Setzer RW. High throughput heuristics for prioritizing human exposure to environmental chemicals. Environmental Science & Technology. 48: 12760-7. PMID 25343693 DOI: 10.1021/Es503583J |
0.398 |
|
| 2014 |
Huang R, Sakamuru S, Martin MT, Reif DM, Judson RS, Houck KA, Casey W, Hsieh JH, Shockley KR, Ceger P, Fostel J, Witt KL, Tong W, Rotroff DM, Zhao T, et al. Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway. Scientific Reports. 4: 5664. PMID 25012808 DOI: 10.1038/Srep05664 |
0.395 |
|
| 2014 |
Rotroff DM, Martin MT, Dix DJ, Filer DL, Houck KA, Knudsen TB, Sipes NS, Reif DM, Xia M, Huang R, Judson RS. Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses. Environmental Science & Technology. 48: 8706-16. PMID 24960280 DOI: 10.1021/Es502676E |
0.461 |
|
| 2014 |
Kleinstreuer NC, Yang J, Berg EL, Knudsen TB, Richard AM, Martin MT, Reif DM, Judson RS, Polokoff M, Dix DJ, Kavlock RJ, Houck KA. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nature Biotechnology. 32: 583-91. PMID 24837663 DOI: 10.1038/Nbt.2914 |
0.585 |
|
| 2014 |
Judson R, Houck K, Martin M, Knudsen T, Thomas RS, Sipes N, Shah I, Wambaugh J, Crofton K. In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme. Basic & Clinical Pharmacology & Toxicology. 115: 69-76. PMID 24684691 DOI: 10.1111/Bcpt.12239 |
0.549 |
|
| 2013 |
Zang Q, Rotroff DM, Judson RS. Binary classification of a large collection of environmental chemicals from estrogen receptor assays by quantitative structure-activity relationship and machine learning methods. Journal of Chemical Information and Modeling. 53: 3244-61. PMID 24279462 DOI: 10.1021/Ci400527B |
0.448 |
|
| 2013 |
Shen J, Xu L, Fang H, Richard AM, Bray JD, Judson RS, Zhou G, Colatsky TJ, Aungst JL, Teng C, Harris SC, Ge W, Dai SY, Su Z, Jacobs AC, et al. EADB: an estrogenic activity database for assessing potential endocrine activity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 135: 277-91. PMID 23897986 DOI: 10.1093/toxsci/kft164 |
0.421 |
|
| 2013 |
Wambaugh JF, Setzer RW, Reif DM, Gangwal S, Mitchell-Blackwood J, Arnot JA, Joliet O, Frame A, Rabinowitz J, Knudsen TB, Judson RS, Egeghy P, Vallero D, Cohen Hubal EA. High-throughput models for exposure-based chemical prioritization in the ExpoCast project. Environmental Science & Technology. 47: 8479-88. PMID 23758710 DOI: 10.1021/Es400482G |
0.455 |
|
| 2013 |
Rotroff DM, Dix DJ, Houck KA, Kavlock RJ, Knudsen TB, Martin MT, Reif DM, Richard AM, Sipes NS, Abassi YA, Jin C, Stampfl M, Judson RS. Real-time growth kinetics measuring hormone mimicry for ToxCast chemicals in T-47D human ductal carcinoma cells. Chemical Research in Toxicology. 26: 1097-107. PMID 23682706 DOI: 10.1021/Tx400117Y |
0.348 |
|
| 2013 |
Sipes NS, Martin MT, Kothiya P, Reif DM, Judson RS, Richard AM, Houck KA, Dix DJ, Kavlock RJ, Knudsen TB. Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays. Chemical Research in Toxicology. 26: 878-95. PMID 23611293 DOI: 10.1021/Tx400021F |
0.558 |
|
| 2013 |
Wetmore BA, Wambaugh JF, Ferguson SS, Li L, Clewell HJ, Judson RS, Freeman K, Bao W, Sochaski MA, Chu TM, Black MB, Healy E, Allen B, Andersen ME, Wolfinger RD, et al. Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 327-46. PMID 23358191 DOI: 10.1093/Toxsci/Kft012 |
0.315 |
|
| 2013 |
Judson R, Kavlock R, Martin M, Reif D, Houck K, Knudsen T, Richard A, Tice RR, Whelan M, Xia M, Huang R, Austin C, Daston G, Hartung T, Fowle JR, et al. Perspectives on validation of high-throughput assays supporting 21st century toxicity testing. Altex. 30: 51-6. PMID 23338806 DOI: 10.14573/Altex.2013.1.051 |
0.417 |
|
| 2013 |
Knudsen T, Martin M, Chandler K, Kleinstreuer N, Judson R, Sipes N. Predictive models and computational toxicology. Methods in Molecular Biology (Clifton, N.J.). 947: 343-74. PMID 23138916 DOI: 10.1007/978-1-62703-131-8_26 |
0.439 |
|
| 2013 |
Rotroff DM, Dix DJ, Houck KA, Knudsen TB, Martin MT, McLaurin KW, Reif DM, Crofton KM, Singh AV, Xia M, Huang R, Judson RS. Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals. Environmental Health Perspectives. 121: 7-14. PMID 23052129 DOI: 10.1289/Ehp.1205065 |
0.518 |
|
| 2013 |
Kleinstreuer NC, Dix DJ, Houck KA, Kavlock RJ, Knudsen TB, Martin MT, Paul KB, Reif DM, Crofton KM, Hamilton K, Hunter R, Shah I, Judson RS. In vitro perturbations of targets in cancer hallmark processes predict rodent chemical carcinogenesis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 131: 40-55. PMID 23024176 DOI: 10.1093/Toxsci/Kfs285 |
0.459 |
|
| 2012 |
Gangwal S, Reif DM, Mosher S, Egeghy PP, Wambaugh JF, Judson RS, Hubal EA. Incorporating exposure information into the toxicological prioritization index decision support framework. The Science of the Total Environment. 435: 316-25. PMID 22863807 DOI: 10.1016/J.Scitotenv.2012.06.086 |
0.367 |
|
| 2012 |
Kavlock R, Chandler K, Houck K, Hunter S, Judson R, Kleinstreuer N, Knudsen T, Martin M, Padilla S, Reif D, Richard A, Rotroff D, Sipes N, Dix D. Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management. Chemical Research in Toxicology. 25: 1287-302. PMID 22519603 DOI: 10.1021/Tx3000939 |
0.411 |
|
| 2012 |
Judson RS, Martin MT, Egeghy P, Gangwal S, Reif DM, Kothiya P, Wolf M, Cathey T, Transue T, Smith D, Vail J, Frame A, Mosher S, Cohen Hubal EA, Richard AM. Aggregating data for computational toxicology applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System. International Journal of Molecular Sciences. 13: 1805-31. PMID 22408426 DOI: 10.3390/Ijms13021805 |
0.454 |
|
| 2012 |
Martin MT, Knudsen TB, Judson RS, Kavlock RJ, Dix DJ. Economic benefits of using adaptive predictive models of reproductive toxicity in the context of a tiered testing program. Systems Biology in Reproductive Medicine. 58: 3-9. PMID 22239076 DOI: 10.3109/19396368.2011.652288 |
0.44 |
|
| 2012 |
Egeghy PP, Judson R, Gangwal S, Mosher S, Smith D, Vail J, Cohen Hubal EA. The exposure data landscape for manufactured chemicals. The Science of the Total Environment. 414: 159-66. PMID 22104386 DOI: 10.1016/J.Scitotenv.2011.10.046 |
0.454 |
|
| 2012 |
Judson RS, Mortensen HM, Shah I, Knudsen TB, Elloumi F. Using pathway modules as targets for assay development in xenobiotic screening. Molecular Biosystems. 8: 531-42. PMID 22075577 DOI: 10.1039/C1Mb05303E |
0.596 |
|
| 2012 |
Wetmore BA, Wambaugh JF, Ferguson SS, Sochaski MA, Rotroff DM, Freeman K, Clewell HJ, Dix DJ, Andersen ME, Houck KA, Allen B, Judson RS, Singh R, Kavlock RJ, Richard AM, et al. Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 157-74. PMID 21948869 DOI: 10.1093/Toxsci/Kfr254 |
0.451 |
|
| 2011 |
Sipes NS, Martin MT, Reif DM, Kleinstreuer NC, Judson RS, Singh AV, Chandler KJ, Dix DJ, Kavlock RJ, Knudsen TB. Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 109-27. PMID 21873373 DOI: 10.1093/Toxsci/Kfr220 |
0.404 |
|
| 2011 |
Kleinstreuer NC, Judson RS, Reif DM, Sipes NS, Singh AV, Chandler KJ, Dewoskin R, Dix DJ, Kavlock RJ, Knudsen TB. Environmental impact on vascular development predicted by high-throughput screening. Environmental Health Perspectives. 119: 1596-603. PMID 21788198 DOI: 10.1289/Ehp.1103412 |
0.531 |
|
| 2011 |
Chandler KJ, Barrier M, Jeffay S, Nichols HP, Kleinstreuer NC, Singh AV, Reif DM, Sipes NS, Judson RS, Dix DJ, Kavlock R, Hunter ES, Knudsen TB. Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay. Plos One. 6: e18540. PMID 21666745 DOI: 10.1371/Journal.Pone.0018540 |
0.375 |
|
| 2011 |
Martin MT, Knudsen TB, Reif DM, Houck KA, Judson RS, Kavlock RJ, Dix DJ. Predictive model of rat reproductive toxicity from ToxCast high throughput screening. Biology of Reproduction. 85: 327-39. PMID 21565999 DOI: 10.1095/Biolreprod.111.090977 |
0.513 |
|
| 2011 |
Huang R, Xia M, Cho MH, Sakamuru S, Shinn P, Houck KA, Dix DJ, Judson RS, Witt KL, Kavlock RJ, Tice RR, Austin CP. Chemical genomics profiling of environmental chemical modulation of human nuclear receptors. Environmental Health Perspectives. 119: 1142-8. PMID 21543282 DOI: 10.1289/ehp.1002952 |
0.556 |
|
| 2011 |
Judson RS, Kavlock RJ, Setzer RW, Hubal EA, Martin MT, Knudsen TB, Houck KA, Thomas RS, Wetmore BA, Dix DJ. Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment. Chemical Research in Toxicology. 24: 451-62. PMID 21384849 DOI: 10.1021/Tx100428E |
0.358 |
|
| 2011 |
Knudsen TB, Houck KA, Sipes NS, Singh AV, Judson RS, Martin MT, Weissman A, Kleinstreuer NC, Mortensen HM, Reif DM, Rabinowitz JR, Setzer RW, Richard AM, Dix DJ, Kavlock RJ. Activity profiles of 309 ToxCastâ„¢ chemicals evaluated across 292 biochemical targets. Toxicology. 282: 1-15. PMID 21251949 DOI: 10.1016/J.Tox.2010.12.010 |
0.618 |
|
| 2010 |
Reif DM, Martin MT, Tan SW, Houck KA, Judson RS, Richard AM, Knudsen TB, Dix DJ, Kavlock RJ. Endocrine profiling and prioritization of environmental chemicals using ToxCast data. Environmental Health Perspectives. 118: 1714-20. PMID 20826373 DOI: 10.1289/Ehp.1002180 |
0.533 |
|
| 2010 |
Rotroff DM, Wetmore BA, Dix DJ, Ferguson SS, Clewell HJ, Houck KA, Lecluyse EL, Andersen ME, Judson RS, Smith CM, Sochaski MA, Kavlock RJ, Boellmann F, Martin MT, Reif DM, et al. Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 348-58. PMID 20639261 DOI: 10.1093/Toxsci/Kfq220 |
0.497 |
|
| 2010 |
Judson RS, Martin MT, Reif DM, Houck KA, Knudsen TB, Rotroff DM, Xia M, Sakamuru S, Huang R, Shinn P, Austin CP, Kavlock RJ, Dix DJ. Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity. Environmental Science & Technology. 44: 5979-85. PMID 20602530 DOI: 10.1021/Es102150Z |
0.319 |
|
| 2010 |
Rotroff DM, Beam AL, Dix DJ, Farmer A, Freeman KM, Houck KA, Judson RS, LeCluyse EL, Martin MT, Reif DM, Ferguson SS. Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 13: 329-46. PMID 20574906 DOI: 10.1080/10937404.2010.483949 |
0.377 |
|
| 2010 |
Judson RS, Houck KA, Kavlock RJ, Knudsen TB, Martin MT, Mortensen HM, Reif DM, Rotroff DM, Shah I, Richard AM, Dix DJ. In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project. Environmental Health Perspectives. 118: 485-92. PMID 20368123 DOI: 10.1289/Ehp.0901392 |
0.608 |
|
| 2010 |
Martin MT, Dix DJ, Judson RS, Kavlock RJ, Reif DM, Richard AM, Rotroff DM, Romanov S, Medvedev A, Poltoratskaya N, Gambarian M, Moeser M, Makarov SS, Houck KA. Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. Chemical Research in Toxicology. 23: 578-90. PMID 20143881 DOI: 10.1021/Tx900325G |
0.477 |
|
| 2009 |
Houck KA, Dix DJ, Judson RS, Kavlock RJ, Yang J, Berg EL. Profiling bioactivity of the ToxCast chemical library using BioMAP primary human cell systems. Journal of Biomolecular Screening. 14: 1054-66. PMID 19773588 DOI: 10.1177/1087057109345525 |
0.467 |
|
| 2009 |
Knight AW, Little S, Houck K, Dix D, Judson R, Richard A, McCarroll N, Akerman G, Yang C, Birrell L, Walmsley RM. Evaluation of high-throughput genotoxicity assays used in profiling the US EPA ToxCast chemicals. Regulatory Toxicology and Pharmacology : Rtp. 55: 188-99. PMID 19591892 DOI: 10.1016/j.yrtph.2009.07.004 |
0.404 |
|
| 2009 |
Judson R, Richard A, Dix DJ, Houck K, Martin M, Kavlock R, Dellarco V, Henry T, Holderman T, Sayre P, Tan S, Carpenter T, Smith E. The toxicity data landscape for environmental chemicals. Environmental Health Perspectives. 117: 685-95. PMID 19479008 DOI: 10.1289/Ehp.0800168 |
0.533 |
|
| 2009 |
Knudsen TB, Martin MT, Kavlock RJ, Judson RS, Dix DJ, Singh AV. Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB. Reproductive Toxicology (Elmsford, N.Y.). 28: 209-19. PMID 19446433 DOI: 10.1016/J.Reprotox.2009.03.016 |
0.379 |
|
| 2009 |
Martin MT, Mendez E, Corum DG, Judson RS, Kavlock RJ, Rotroff DM, Dix DJ. Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database. Toxicological Sciences : An Official Journal of the Society of Toxicology. 110: 181-90. PMID 19363143 DOI: 10.1093/Toxsci/Kfp080 |
0.423 |
|
| 2009 |
Martin MT, Judson RS, Reif DM, Kavlock RJ, Dix DJ. Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database. Environmental Health Perspectives. 117: 392-9. PMID 19337514 DOI: 10.1289/Ehp.0800074 |
0.331 |
|
| 2008 |
Richard AM, Yang C, Judson RS. Toxicity data informatics: supporting a new paradigm for toxicity prediction. Toxicology Mechanisms and Methods. 18: 103-18. PMID 20020908 DOI: 10.1080/15376510701857452 |
0.344 |
|
| 2008 |
Judson R, Richard A, Dix D, Houck K, Elloumi F, Martin M, Cathey T, Transue TR, Spencer R, Wolf M. ACToR--Aggregated Computational Toxicology Resource. Toxicology and Applied Pharmacology. 233: 7-13. PMID 18671997 DOI: 10.1016/J.Taap.2007.12.037 |
0.359 |
|
| 2008 |
Kavlock RJ, Ankley G, Blancato J, Breen M, Conolly R, Dix D, Houck K, Hubal E, Judson R, Rabinowitz J, Richard A, Setzer RW, Shah I, Villeneuve D, Weber E. Computational toxicology--a state of the science mini review. Toxicological Sciences : An Official Journal of the Society of Toxicology. 103: 14-27. PMID 18065772 DOI: 10.1093/toxsci/kfm297 |
0.319 |
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