Rutilio A. Fratti - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Membrane fusion, Phosphoinositides, SNAREs

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hurst LR, Fratti RA. Lipid Rafts, Sphingolipids, and Ergosterol in Yeast Vacuole Fusion and Maturation. Frontiers in Cell and Developmental Biology. 8: 539. PMID 32719794 DOI: 10.3389/Fcell.2020.00539  0.487
2020 Miner GE, Sullivan KD, Zhang C, Rivera-Kohr D, Guo A, Hurst LR, Ellis EC, Starr ML, Jones BC, Fratti RA. Phosphatidylinositol 3,5-Bisphosphate regulates Ca Transport During Yeast Vacuolar Fusion through the Ca ATPase Pmc1. Traffic (Copenhagen, Denmark). PMID 32388897 DOI: 10.1111/Tra.12736  0.358
2019 Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA. A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion. The Journal of Biological Chemistry. PMID 31515268 DOI: 10.1074/Jbc.Ra119.008865  0.511
2019 Sparks RP, Lui A, Bader D, Patel R, Murr M, Guida W, Fratti RA, Patel NA. A specific small-molecule inhibitor of Protein Kinase CδI activity improves metabolic dysfunction in human adipocytes from obese individuals. The Journal of Biological Chemistry. PMID 31413114 DOI: 10.1074/Jbc.Ra119.008777  0.311
2019 Miner GE, Sullivan KD, Zhang C, Hurst LR, Starr ML, Rivera-Kohr DA, Jones BC, Guo A, Fratti RA. Copper blocks V-ATPase activity and SNARE complex formation to inhibit yeast vacuole fusion. Traffic (Copenhagen, Denmark). PMID 31368617 DOI: 10.1111/Tra.12683  0.368
2019 Starr ML, Sparks RP, Arango AS, Hurst LR, Zhao Z, Lihan M, Jenkins JL, Tajkhorshid E, Fratti RA. Phosphatidic acid induces conformational changes in Sec18 protomers that prevent SNARE priming. The Journal of Biological Chemistry. PMID 30617180 DOI: 10.1074/Jbc.Ra118.006552  0.475
2019 Sparks RP, Jenkins JL, Fratti R. Use of Surface Plasmon Resonance (SPR) to Determine Binding Affinities and Kinetic Parameters Between Components Important in Fusion Machinery. Methods in Molecular Biology (Clifton, N.J.). 1860: 199-210. PMID 30317506 DOI: 10.1007/978-1-4939-8760-3_12  0.322
2019 Sparks RP, Fratti R. Use of Microscale Thermophoresis (MST) to Measure Binding Affinities of Components of the Fusion Machinery. Methods in Molecular Biology (Clifton, N.J.). 1860: 191-198. PMID 30317505 DOI: 10.1007/978-1-4939-8760-3_11  0.335
2019 Arango AS, Sparks RP, Starr ML, Zhao Z, Lihan M, Fratti R, Tajkhorshid E. Snare Priming Inhibition via Phosphatidic Acid Induced Sec18 Conformational Changes and Competitive Small Molecule Binding to Sec18 Biophysical Journal. 116: 229a. DOI: 10.1016/J.Bpj.2018.11.1258  0.312
2018 Starr ML, Fratti RA. The Participation of Regulatory Lipids in Vacuole Homotypic Fusion. Trends in Biochemical Sciences. PMID 30587414 DOI: 10.1016/J.Tibs.2018.12.003  0.51
2018 Miner GE, Sullivan KD, Guo A, Jones BC, Hurst LR, Ellis EC, Starr ML, Fratti RA. Phosphatidylinositol 3,5-Bisphosphate Regulates the Transition between trans-SNARE Complex Formation and Vacuole Membrane Fusion. Molecular Biology of the Cell. mbcE18080505. PMID 30427760 DOI: 10.1091/Mbc.E18-08-0505  0.491
2017 Miner GE, Starr ML, Hurst LR, Fratti RA. Deleting the DAG Kinase Dgk1 Augments Yeast Vacuole Fusion Through Increased Ypt7 Activity and Altered Membrane Fluidity. Traffic (Copenhagen, Denmark). PMID 28276191 DOI: 10.1111/Tra.12479  0.482
2016 Sparks RP, Jenkins JL, Miner GE, Wang Y, Guida WC, Sparks CE, Fratti RA, Sparks JD. Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding. Biochemical and Biophysical Research Communications. PMID 27666481 DOI: 10.1016/J.Bbrc.2016.09.108  0.314
2016 Miner GE, Starr ML, Hurst LR, Sparks RP, Padolina M, Fratti RA. The Central Polybasic Region of the Soluble SNARE Vam7 Affects Binding to Phosphatidylinositol 3-phosphate by the PX domain. The Journal of Biological Chemistry. PMID 27365394 DOI: 10.1074/Jbc.M116.725366  0.778
2016 Starr ML, Hurst LR, Fratti RA. Phosphatidic acid sequesters Sec18p from cis-SNARE complexes to inhibit priming. Traffic (Copenhagen, Denmark). PMID 27364524 DOI: 10.1111/Tra.12423  0.424
2014 Sasser TL, Fratti RA. Class C ABC transporters and Saccharomyces cerevisiae vacuole fusion. Cellular Logistics. 4: e943588. PMID 25610719 DOI: 10.4161/21592780.2014.943588  0.793
2014 Lawrence G, Brown CC, Flood BA, Karunakaran S, Cabrera M, Nordmann M, Ungermann C, Fratti RA. Dynamic association of the PI3P-interacting Mon1-Ccz1 GEF with vacuoles is controlled through its phosphorylation by the type 1 casein kinase Yck3. Molecular Biology of the Cell. 25: 1608-19. PMID 24623720 DOI: 10.1091/Mbc.E13-08-0460  0.772
2013 Sasser TL, Lawrence G, Karunakaran S, Brown C, Fratti RA. The yeast ATP-binding cassette (ABC) transporter Ycf1p enhances the recruitment of the soluble SNARE Vam7p to vacuoles for efficient membrane fusion. The Journal of Biological Chemistry. 288: 18300-10. PMID 23658021 DOI: 10.1074/Jbc.M112.441089  0.808
2013 Karunakaran S, Fratti RA. The lipid composition and physical properties of the yeast vacuole affect the hemifusion-fusion transition. Traffic (Copenhagen, Denmark). 14: 650-62. PMID 23438067 DOI: 10.1111/Tra.12064  0.731
2012 Sasser TL, Padolina M, Fratti RA. The yeast vacuolar ABC transporter Ybt1p regulates membrane fusion through Ca2+ transport modulation. The Biochemical Journal. 448: 365-72. PMID 22970809 DOI: 10.1042/Bj20120847  0.767
2012 Karunakaran S, Sasser T, Rajalekshmi S, Fratti RA. SNAREs, HOPS and regulatory lipids control the dynamics of vacuolar actin during homotypic fusion in S. cerevisiae. Journal of Cell Science. 125: 1683-92. PMID 22357954 DOI: 10.1242/Jcs.091900  0.749
2012 Sasser T, Qiu QS, Karunakaran S, Padolina M, Reyes A, Flood B, Smith S, Gonzales C, Fratti RA. Yeast lipin 1 orthologue pah1p regulates vacuole homeostasis and membrane fusion. The Journal of Biological Chemistry. 287: 2221-36. PMID 22121197 DOI: 10.1074/Jbc.M111.317420  0.763
2010 Qiu QS, Fratti RA. The Na+/H+ exchanger Nhx1p regulates the initiation of Saccharomyces cerevisiae vacuole fusion. Journal of Cell Science. 123: 3266-75. PMID 20826459 DOI: 10.1242/Jcs.067637  0.698
2007 Fratti RA, Collins KM, Hickey CM, Wickner W. Stringent 3Q.1R composition of the SNARE 0-layer can be bypassed for fusion by compensatory SNARE mutation or by lipid bilayer modification. The Journal of Biological Chemistry. 282: 14861-7. PMID 17400548 DOI: 10.1074/Jbc.M700971200  0.791
2007 Fratti RA, Wickner W. Distinct targeting and fusion functions of the PX and SNARE domains of yeast vacuolar Vam7p. The Journal of Biological Chemistry. 282: 13133-8. PMID 17347148 DOI: 10.1074/Jbc.M700584200  0.658
2006 Jun Y, Thorngren N, Starai VJ, Fratti RA, Collins K, Wickner W. Reversible, cooperative reactions of yeast vacuole docking. The Embo Journal. 25: 5260-9. PMID 17082764 DOI: 10.1038/Sj.Emboj.7601413  0.77
2006 Stroupe C, Collins KM, Fratti RA, Wickner W. Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p. The Embo Journal. 25: 1579-89. PMID 16601699 DOI: 10.1038/Sj.Emboj.7601051  0.752
2005 Collins KM, Thorngren NL, Fratti RA, Wickner WT. Sec17p and HOPS, in distinct SNARE complexes, mediate SNARE complex disruption or assembly for fusion. The Embo Journal. 24: 1775-86. PMID 15889152 DOI: 10.1038/Sj.Emboj.7600658  0.757
2005 Starai VJ, Thorngren N, Fratti RA, Wickner W. Ion regulation of homotypic vacuole fusion in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 280: 16754-62. PMID 15737991 DOI: 10.1074/Jbc.M500421200  0.646
2005 Phan QT, Fratti RA, Prasadarao NV, Edwards JE, Filler SG. N-cadherin mediates endocytosis of Candida albicans by endothelial cells. The Journal of Biological Chemistry. 280: 10455-61. PMID 15632157 DOI: 10.1074/jbc.M412592200  0.442
2004 Fratti RA, Jun Y, Merz AJ, Margolis N, Wickner W. Interdependent assembly of specific regulatory lipids and membrane fusion proteins into the vertex ring domain of docked vacuoles. The Journal of Cell Biology. 167: 1087-98. PMID 15611334 DOI: 10.1083/Jcb.200409068  0.767
2004 Jun Y, Fratti RA, Wickner W. Diacylglycerol and its formation by phospholipase C regulate Rab- and SNARE-dependent yeast vacuole fusion. The Journal of Biological Chemistry. 279: 53186-95. PMID 15485855 DOI: 10.1074/Jbc.M411363200  0.7
2004 Thorngren N, Collins KM, Fratti RA, Wickner W, Merz AJ. A soluble SNARE drives rapid docking, bypassing ATP and Sec17/18p for vacuole fusion. The Embo Journal. 23: 2765-76. PMID 15241469 DOI: 10.1038/Sj.Emboj.7600286  0.807
2004 Miller BH, Fratti RA, Poschet JF, Timmins GS, Master SS, Burgos M, Marletta MA, Deretic V. Mycobacteria inhibit nitric oxide synthase recruitment to phagosomes during macrophage infection. Infection and Immunity. 72: 2872-8. PMID 15102799 DOI: 10.1128/Iai.72.5.2872-2878.2004  0.552
2004 Vergne I, Fratti RA, Hill PJ, Chua J, Belisle J, Deretic V. Mycobacterium tuberculosis phagosome maturation arrest: mycobacterial phosphatidylinositol analog phosphatidylinositol mannoside stimulates early endosomal fusion. Molecular Biology of the Cell. 15: 751-60. PMID 14617817 DOI: 10.1091/Mbc.E03-05-0307  0.751
2003 Fratti RA, Chua J, Deretic V. Induction of p38 mitogen-activated protein kinase reduces early endosome autoantigen 1 (EEA1) recruitment to phagosomal membranes. The Journal of Biological Chemistry. 278: 46961-7. PMID 12963735 DOI: 10.1074/Jbc.M305225200  0.699
2003 Fratti RA, Chua J, Vergne I, Deretic V. Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. Proceedings of the National Academy of Sciences of the United States of America. 100: 5437-42. PMID 12702770 DOI: 10.1073/Pnas.0737613100  0.681
2002 Belanger PH, Johnston DA, Fratti RA, Zhang M, Filler SG. Endocytosis of Candida albicans by vascular endothelial cells is associated with tyrosine phosphorylation of specific host cell proteins. Cellular Microbiology. 4: 805-12. PMID 12464011 DOI: 10.1046/J.1462-5822.2002.00232.X  0.539
2002 Fratti RA, Chua J, Deretic V. Cellubrevin alterations and Mycobacterium tuberculosis phagosome maturation arrest. The Journal of Biological Chemistry. 277: 17320-6. PMID 11825909 DOI: 10.1074/Jbc.M200335200  0.725
2001 Fratti RA, Backer JM, Gruenberg J, Corvera S, Deretic V. Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. The Journal of Cell Biology. 154: 631-44. PMID 11489920 DOI: 10.1083/Jcb.200106049  0.646
2000 Fratti RA, Vergne I, Chua J, Skidmore J, Deretic V. Regulators of membrane trafficking and Mycobacterium tuberculosis phagosome maturation block. Electrophoresis. 21: 3378-85. PMID 11079558 DOI: 10.1002/1522-2683(20001001)21:16<3378::Aid-Elps3378>3.0.Co;2-B  0.731
1999 Deretic V, Fratti RA. Mycobacterium tuberculosis phagosome. Molecular Microbiology. 31: 1603-9. PMID 10209735 DOI: 10.1046/J.1365-2958.1999.01279.X  0.636
1998 Via LE, Fratti RA, McFalone M, Pagan-Ramos E, Deretic D, Deretic V. Effects of cytokines on mycobacterial phagosome maturation. Journal of Cell Science. 111: 897-905. PMID 9490634  0.477
1998 Fratti RA, Belanger PH, Ghannoum MA, Edwards JE, Filler SG. Endothelial cell injury caused by Candida albicans is dependent on iron. Infection and Immunity. 66: 191-6. PMID 9423857 DOI: 10.1128/Iai.66.1.191-196.1998  0.481
1997 Deretic V, Via LE, Fratti RA, Deretic D. Mycobacterial phagosome maturation, rab proteins, and intracellular trafficking. Electrophoresis. 18: 2542-7. PMID 9527483 DOI: 10.1002/Elps.1150181409  0.649
1996 Fratti RA, Ghannoum MA, Edwards JE, Filler SG. Gamma interferon protects endothelial cells from damage by Candida albicans by inhibiting endothelial cell phagocytosis. Infection and Immunity. 64: 4714-8. PMID 8890230 DOI: 10.1128/Iai.64.11.4714-4718.1996  0.486
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