| Year |
Citation |
Score |
| 2024 |
Rivera-Hernandez T, Carnathan DG, Richter J, Marchant P, Cork AJ, Elangovan G, Henningham A, Cole JN, Choudhury B, Moyle PM, Toth I, Batzloff MR, Good MF, Agarwal P, Kapoor N, et al. Efficacy of Alum-Adjuvanted Peptide and Carbohydrate Conjugate Vaccine Candidates against Group A Pharyngeal Infection in a Non-Human Primate Model. Vaccines. 12. PMID 38675764 DOI: 10.3390/vaccines12040382 |
0.438 |
|
| 2023 |
Sinclair F, Begum AA, Dai CC, Toth I, Moyle PM. Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing. Drug Delivery and Translational Research. 13: 1500-1519. PMID 36988873 DOI: 10.1007/s13346-023-01320-z |
0.694 |
|
| 2020 |
Rivera-Hernandez T, Carnathan DG, Jones S, Cork AJ, Davies MR, Moyle PM, Toth I, Batzloff MR, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ. Erratum for Rivera-Hernandez et al., "An Experimental Group A Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model". Mbio. 11. PMID 33262263 DOI: 10.1128/mBio.02995-20 |
0.492 |
|
| 2020 |
Xu Z, Rivera-Hernandez T, Moyle PM. Development of an Enzyme-Mediated, Site-Specific Method to Conjugate Toll-Like Receptor 2 Agonists onto Protein Antigens: Toward a Broadly Protective, Four Component, Group A Streptococcal Self-Adjuvanting Lipoprotein-Fusion Combination Vaccine. Acs Infectious Diseases. PMID 32407620 DOI: 10.1021/acsinfecdis.0c00047 |
0.377 |
|
| 2019 |
Xu Z, Rivera-Hernandez T, Chatterjee O, Walker MJ, Moyle PM. Semisynthetic, self-adjuvanting vaccine development: Efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31758971 DOI: 10.1016/j.jconrel.2019.11.018 |
0.337 |
|
| 2019 |
Hussein W, Cheong Y, Liu C, Liu G, Begum A, Attallah MA, Moyle PM, Torchilin V, Smith R, Toth I. Peptide-based targeted polymeric nanoparticles for siRNA delivery. Nanotechnology. PMID 31295734 DOI: 10.1088/1361-6528/Ab313D |
0.532 |
|
| 2019 |
Ara Beguma A, Toth I, Hussein WM, Moyle PM. Advances in targeted gene delivery. Current Drug Delivery. PMID 31142250 DOI: 10.2174/1567201816666190529072914 |
0.501 |
|
| 2019 |
Begum AA, Toth I, Moyle PM. Gastrin-releasing peptide receptor-targeted hybrid peptide/phospholipid pDNA/siRNA delivery systems. Nanomedicine (London, England). PMID 31050581 DOI: 10.2217/nnm-2018-0380 |
0.566 |
|
| 2019 |
Rivera-Hernandez T, Carnathan DG, Jones S, Cork AJ, Davies MR, Moyle PM, Toth I, Batzloff MR, McCarthy J, Nizet V, Goldblatt D, Silvestri G, Walker MJ. An Experimental Group A Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model. Mbio. 10. PMID 31040243 DOI: 10.1128/Mbio.00693-19 |
0.556 |
|
| 2017 |
Begum AA, Wan Y, Toth I, Moyle PM. Bombesin/oligoarginine fusion peptides for gastrin releasing peptide receptor (GRPR) targeted gene delivery. Bioorganic & Medicinal Chemistry. PMID 29269254 DOI: 10.1016/j.bmc.2017.12.013 |
0.569 |
|
| 2017 |
Xu Z, Moyle PM. Bioconjugation Approaches to Produce Subunit Vaccines Composed of Protein or Peptide Antigens and Covalently Attached Toll-Like Receptor Ligands. Bioconjugate Chemistry. PMID 28891637 DOI: 10.1021/acs.bioconjchem.7b00478 |
0.394 |
|
| 2017 |
Wan Y, Dai W, J Nevagi R, Toth I, Moyle PM. Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells. Acta Biomaterialia. PMID 28655658 DOI: 10.1016/j.actbio.2017.06.032 |
0.548 |
|
| 2017 |
Moyle PM. Biotechnology approaches to produce potent, self-adjuvanting antigen-adjuvant fusion protein subunit vaccines. Biotechnology Advances. PMID 28288861 DOI: 10.1016/j.biotechadv.2017.03.005 |
0.411 |
|
| 2017 |
Wan Y, Moyle PM, Gn PZ, Toth I. Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery. Nanomedicine (London, England). PMID 28093948 DOI: 10.2217/nnm-2016-0354 |
0.551 |
|
| 2016 |
Hussein WM, Liu TY, Maruthayanar P, Mukaida S, Moyle PM, Wells JW, Toth I, Skwarczynski M. Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines. Chemical Science. 7: 2308-2321. PMID 29910921 DOI: 10.1039/c5sc03859f |
0.615 |
|
| 2016 |
Begum AA, Moyle PM, Toth I. Investigation of bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor. Bioorganic & Medicinal Chemistry. PMID 27670095 DOI: 10.1016/j.bmc.2016.09.039 |
0.518 |
|
| 2016 |
Rivera-Hernandez T, Pandey M, Henningham A, Cole J, Choudhury B, Cork AJ, Gillen CM, Ghaffar KA, West NP, Silvestri G, Good MF, Moyle PM, Toth I, Nizet V, Batzloff MR, et al. Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models. Mbio. 7. PMID 27302756 DOI: 10.1128/Mbio.00618-16 |
0.587 |
|
| 2016 |
Wan Y, Moyle PM, Christie MP, Toth I. Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity. Nanomedicine (London, England). PMID 26979574 DOI: 10.2217/nnm.16.27 |
0.555 |
|
| 2016 |
Hussein WM, Liu TY, Maruthayanar P, Mukaida S, Moyle PM, Wells JW, Toth I, Skwarczynski M. Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines Chemical Science. 7: 2308-2321. DOI: 10.1039/c5sc03859f |
0.4 |
|
| 2015 |
Moyle PM, Dai W, Liu TY, Hussein WM, Maruthayanar P, Wells JW, McMillan NA, Skwarczynski M, Toth I. Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors. Bioorganic & Medicinal Chemistry Letters. 25: 5570-5. PMID 26514746 DOI: 10.1016/j.bmcl.2015.10.049 |
0.505 |
|
| 2015 |
Wan Y, Moyle PM, Toth I. Endosome Escape Strategies for Improving the Efficacy of Oligonucleotide Delivery Systems. Current Medicinal Chemistry. 22: 3326-46. PMID 26303176 |
0.363 |
|
| 2015 |
Rosli N, Christie MP, Moyle PM, Toth I. Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons. Bioorganic & Medicinal Chemistry. 23: 2470-9. PMID 25882529 DOI: 10.1016/j.bmc.2015.03.058 |
0.548 |
|
| 2015 |
Moyle PM. Progress in vaccine development. Current Protocols in Microbiology. 36: 18.1.1-18.1.26. PMID 25641099 DOI: 10.1002/9780471729259.mc1801s36 |
0.422 |
|
| 2014 |
Rivera-Hernandez T, Carnathan DG, Moyle PM, Toth I, West NP, Young PR, Silvestri G, Walker MJ. The contribution of non-human primate models to the development of human vaccines. Discovery Medicine. 18: 313-22. PMID 25549702 |
0.523 |
|
| 2014 |
Zaman M, Chandrudu S, Giddam AK, Reiman J, Skwarczynski M, McPhun V, Moyle PM, Batzloff MR, Good MF, Toth I. Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity. Nanomedicine (London, England). 9: 2613-24. PMID 25529566 DOI: 10.2217/Nnm.14.190 |
0.597 |
|
| 2014 |
Moyle PM, Dai W, Zhang Y, Batzloff MR, Good MF, Toth I. Site-specific incorporation of three toll-like receptor 2 targeting adjuvants into semisynthetic, molecularly defined nanoparticles: application to group a streptococcal vaccines. Bioconjugate Chemistry. 25: 965-78. PMID 24712905 DOI: 10.1021/bc500108b |
0.622 |
|
| 2014 |
Ahmad Fuaad AA, Jia Z, Zaman M, Hartas J, Ziora ZM, Lin IC, Moyle PM, Batzloff MR, Good MF, Monteiro MJ, Skwarczynski M, Toth I. Polymer-peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine (London, England). 9: 35-43. PMID 23611619 DOI: 10.2217/nnm.13.7 |
0.551 |
|
| 2013 |
Moyle PM, Hartas J, Henningham A, Batzloff MR, Good MF, Toth I. An efficient, chemically-defined semisynthetic lipid-adjuvanted nanoparticulate vaccine development system. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 935-44. PMID 23428988 DOI: 10.1016/j.nano.2013.01.009 |
0.589 |
|
| 2013 |
Moyle PM, Toth I. Modern subunit vaccines: development, components, and research opportunities. Chemmedchem. 8: 360-76. PMID 23316023 DOI: 10.1002/cmdc.201200487 |
0.585 |
|
| 2011 |
Simerska P, Moyle PM, Toth I. Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products. Medicinal Research Reviews. 31: 520-47. PMID 20027671 DOI: 10.1002/med.20191 |
0.648 |
|
| 2010 |
Moyle PM, Muir TW. Method for the synthesis of mono-ADP-ribose conjugated peptides. Journal of the American Chemical Society. 132: 15878-80. PMID 20968292 DOI: 10.1021/Ja1064312 |
0.521 |
|
| 2009 |
Simerska P, Moyle PM, Olive C, Toth I. Oral vaccine delivery--new strategies and technologies. Current Drug Delivery. 6: 347-58. PMID 19534712 DOI: 10.2174/156720109789000537 |
0.611 |
|
| 2009 |
Toth I, Moyle PM, Simerska P, Fujita Y, Olive C, Good MF. Vaccine delivery: synthesis and investigation of a highly pure, multi-epitopic lipopeptide vaccine candidate. Advances in Experimental Medicine and Biology. 611: 347-9. PMID 19400221 DOI: 10.1007/978-0-387-73657-0_154 |
0.603 |
|
| 2009 |
Simerska P, McGeary RP, Abdel-Aal AB, Moyle PM, Olive C, Good MF, Toth I. Vaccine delivery utilizing liposaccharides. Advances in Experimental Medicine and Biology. 611: 345-6. PMID 19400220 DOI: 10.1007/978-0-387-73657-0_153 |
0.604 |
|
| 2008 |
Fujita Y, Moyle PM, Hieu S, Simerska P, Toth I. Investigation toward multi-epitope vaccine candidates using native chemical ligation. Biopolymers. 90: 624-32. PMID 18979543 DOI: 10.1002/bip.21002 |
0.633 |
|
| 2008 |
Moyle PM, Toth I. Self-adjuvanting lipopeptide vaccines. Current Medicinal Chemistry. 15: 506-16. PMID 18289006 DOI: 10.2174/092986708783503249 |
0.643 |
|
| 2008 |
Simerska P, Abdel-Aal AB, Fujita Y, Moyle PM, McGeary RP, Batzloff MR, Olive C, Good MF, Toth I. Development of a liposaccharide-based delivery system and its application to the design of group A streptococcal vaccines. Journal of Medicinal Chemistry. 51: 1447-52. PMID 18278857 DOI: 10.1021/jm701410p |
0.619 |
|
| 2008 |
Abdel-Aal AB, Batzloff MR, Fujita Y, Barozzi N, Faria A, Simerska P, Moyle PM, Good MF, Toth I. Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group a streptococcal vaccine candidates. Journal of Medicinal Chemistry. 51: 167-72. PMID 18072728 DOI: 10.1021/jm701091d |
0.571 |
|
| 2007 |
Olive C, Moyle PM, Toth I. Towards the development of a broadly protective group a streptococcal vaccine based on the Lipid-Core Peptide system. Current Medicinal Chemistry. 14: 2976-88. PMID 18220734 DOI: 10.2174/092986707782794069 |
0.509 |
|
| 2007 |
Moyle PM, Olive C, Ho MF, Pandey M, Dyer J, Suhrbier A, Fujita Y, Toth I. Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. Journal of Medicinal Chemistry. 50: 4721-7. PMID 17705361 DOI: 10.1021/jm070287b |
0.58 |
|
| 2007 |
Moyle PM, Hari Y, Huang N, Olive C, Good MF, Toth I. A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines Tetrahedron Letters. 48: 4965-4967. DOI: 10.1016/j.tetlet.2007.05.129 |
0.452 |
|
| 2006 |
Moyle PM, Olive C, Good MF, Toth I. Method for the synthesis of highly pure vaccines using the lipid core peptide system. Journal of Peptide Science : An Official Publication of the European Peptide Society. 12: 800-7. PMID 17131293 DOI: 10.1002/psc.815 |
0.654 |
|
| 2006 |
Moyle PM, Olive C, Ho MF, Good MF, Toth I. Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A streptococcal vaccine, and subsequent immunological evaluation. Journal of Medicinal Chemistry. 49: 6364-70. PMID 17034142 DOI: 10.1021/jm060475m |
0.652 |
|
| 2006 |
Moyle PM, Olive C, Ho MF, Burgess M, Karpati L, Good MF, Toth I. Method for the synthesis of multi-epitopic Streptococcus pyogenes lipopeptide vaccines using native chemical ligation. The Journal of Organic Chemistry. 71: 6846-50. PMID 16930036 DOI: 10.1021/jo060960p |
0.635 |
|
| 2006 |
Moyle PM, Olive C, Ho Mf, Burgess M, Karpati L, Good M, Toth I. Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptococcal lipopeptide vaccine International Congress Series. 1289: 324-328. DOI: 10.1016/j.ics.2005.11.084 |
0.366 |
|
| 2006 |
Toth I, Moyle P, Karpati L, Horvath A, Olive C, Good M. The lipid core peptide system in vaccine delivery International Congress Series. 1289: 307-310. DOI: 10.1016/j.ics.2005.11.057 |
0.49 |
|
| 2006 |
Moyle PM, Olive C, Karpati L, Barozzi N, Ho MF, Dyer J, Sun HK, Good M, Toth I. Synthesis and immunological evaluation of M protein targeted tetra-valent and tri-valent group A streptococcal vaccine candidates based on the lipid-core peptide system International Journal of Peptide Research and Therapeutics. 12: 317-326. DOI: 10.1007/s10989-006-9021-8 |
0.443 |
|
| 2004 |
Moyle PM, McGeary RP, Blanchfield JT, Toth I. Mucosal immunisation: adjuvants and delivery systems. Current Drug Delivery. 1: 385-96. PMID 16305400 |
0.429 |
|
| 2003 |
Moyle PM, Horvath A, Olive C, Good MF, Toth I. Development of lipid-core-peptide (LCP) based vaccines for the prevention of group A streptococcal (GAS) infection Letters in Peptide Science. 10: 605-613. DOI: 10.1007/BF02442594 |
0.407 |
|
| Show low-probability matches. |