Guido Silvestri - Publications

Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Havenar-Daughton C, Reiss SM, Carnathan DG, Wu JE, Kendric K, Torrents de la Peña A, Kasturi SP, Dan JM, Bothwell M, Sanders RW, Pulendran B, Silvestri G, Crotty S. Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique. Journal of Immunology (Baltimore, Md. : 1950). PMID 27335502 DOI: 10.4049/jimmunol.1600320  0.68
2016 Rivera-Hernandez T, Pandey M, Henningham A, Cole J, Choudhury B, Cork AJ, Gillen CM, Ghaffar KA, West NP, Silvestri G, Good MF, Moyle PM, Toth I, Nizet V, Batzloff MR, et al. Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models. Mbio. 7. PMID 27302756 DOI: 10.1128/mBio.00618-16  0.68
2016 Calascibetta F, Micci L, Carnathan D, Lawson B, Vanderford TH, Bosinger SE, Easley K, Chahroudi A, Mackel J, Keele BF, Long S, Lifson J, Paiardini M, Silvestri G. Antiretroviral therapy in SIV-infected sooty mangabeys: implications for AIDS pathogenesis. Journal of Virology. PMID 27279614 DOI: 10.1128/JVI.00598-16  0.68
2016 Ortiz AM, Carnathan DG, Yu J, Sheehan KM, Kim P, Reynaldi A, Vanderford TH, Klatt NR, Brenchley JM, Davenport MP, Silvestri G. Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys. Plos One. 11: e0156352. PMID 27227993 DOI: 10.1371/journal.pone.0156352  0.68
2016 Kumar N, Chahroudi A, Silvestri G. Animal models to achieve an HIV cure. Current Opinion in Hiv and Aids. PMID 27152962 DOI: 10.1097/COH.0000000000000290  0.68
2016 Jacobson J, Bosinger S, Kang M, Belaunzaran-Zamudio P, Matining RM, Wilson C, Flexner CW, Clagett B, Plants J, Read S, Purdue L, Myers L, Boone L, Tebas P, Kumar P, ... ... Silvestri G, et al. The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1. Aids Research and Human Retroviruses. PMID 26935044 DOI: 10.1089/AID.2015.0336  0.68
2016 Chahroudi A, Silvestri G. HIV and Tfh Cells: Circulating New Ideas to Identify and Protect. Immunity. 44: 16-8. PMID 26789919 DOI: 10.1016/j.immuni.2015.12.016  0.68
2016 Silvestri G, Cartwright EK. HIV and AIDS: Science Wrestles with 10,000 Nucleotides-Points but No Pin Viral Pathogenesis: From Basics to Systems Biology: Third Edition. 107-123. DOI: 10.1016/B978-0-12-800964-2.00009-4  0.68
2015 Micci L, Ryan ES, Fromentin R, Bosinger SE, Harper JL, He T, Paganini S, Easley KA, Chahroudi A, Benne C, Gumber S, McGary CS, Rogers KA, Deleage C, Lucero C, ... ... Silvestri G, et al. Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques. The Journal of Clinical Investigation. PMID 26551680 DOI: 10.1172/JCI81400  0.68
2015 Silvestri G, Barry PA. Editorial overview: Host pathogens: New paradigms and tools to decipher and deconstruct the host-pathogen interaction. Current Opinion in Immunology. PMID 26359003 DOI: 10.1016/j.coi.2015.08.004  0.68
2015 Chowdhury A, Del Rio PM, Tharp GK, Trible RP, Amara RR, Chahroudi A, Reyes-Teran G, Bosinger SE, Silvestri G. Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection. Journal of Immunology (Baltimore, Md. : 1950). 195: 3237-47. PMID 26297764 DOI: 10.4049/jimmunol.1402701  0.68
2015 Burton SL, Kilgore KM, Smith SA, Reddy S, Hunter E, Robinson HL, Silvestri G, Amara RR, Derdeyn CA. Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinated rhesus macaques despite potent autologous neutralizing antibody responses. Proceedings of the National Academy of Sciences of the United States of America. PMID 26261312 DOI: 10.1073/pnas.1509731112  0.68
2015 Mir KD, Mavigner M, Wang C, Paiardini M, Sodora DL, Chahroudi AM, Bosinger SM, Silvestri G. Reduced SIV replication in macrophages of sooty mangabeys is associated with increased expression of host restriction factors. Journal of Virology. PMID 26202248 DOI: 10.1128/JVI.00710-15  0.68
2015 Elliott ST, Wetzel KS, Francella N, Bryan S, Romero DC, Riddick NE, Shaheen F, Vanderford T, Derdeyn CA, Silvestri G, Paiardini M, Collman RG. Dualtropic CXCR6/CCR5 Simian Immunodeficiency Virus (SIV) Infection of Sooty Mangabey Primary Lymphocytes: Distinct Coreceptor Use in Natural versus Pathogenic Hosts of SIV. Journal of Virology. 89: 9252-61. PMID 26109719 DOI: 10.1128/JVI.01236-15  0.68
2015 Chowdhury A, Hayes TL, Bosinger SE, Lawson BO, Vanderford T, Schmitz JE, Paiardini M, Betts M, Chahroudi A, Estes JD, Silvestri G. Differential impact of in vivo CD8+ T-lymphocyte depletion in controller versus progressor SIV-infected macaques. Journal of Virology. PMID 26063417 DOI: 10.1128/JVI.00869-15  0.68
2015 Kilgore KM, Murphy MK, Burton SL, Wetzel KS, Smith SA, Xiao P, Reddy S, Francella N, Sodora DL, Silvestri G, Cole KS, Villinger F, Robinson JE, Pulendran B, Hunter E, et al. Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope. Journal of Virology. 89: 8130-51. PMID 26018167 DOI: 10.1128/JVI.01221-14  0.68
2015 Jochems SP, Jacquelin B, Chauveau L, Huot N, Petitjean G, Lepelley A, Liovat AS, Ploquin MJ, Cartwright EK, Bosinger SE, Silvestri G, Barré-Sinoussi F, Lebon P, Schwartz O, Müller-Trutwin MC. Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection. Journal of Virology. 89: 6918-27. PMID 25903334 DOI: 10.1128/JVI.00332-15  0.68
2015 Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN, Mouquet H, Martin L, ... ... Silvestri G, et al. Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas. Mbio. 6. PMID 25900654 DOI: 10.1128/mBio.00296-15  0.68
2015 Claiborne DT, Prince JL, Scully E, Macharia G, Micci L, Lawson B, Kopycinski J, Deymier MJ, Vanderford TH, Nganou-Makamdop K, Ende Z, Brooks K, Tang J, Yu T, Lakhi S, ... ... Silvestri G, et al. Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression. Proceedings of the National Academy of Sciences of the United States of America. 112: E1480-9. PMID 25730868 DOI: 10.1073/pnas.1421607112  0.68
2015 Chahroudi A, Silvestri G, Lichterfeld M. T memory stem cells and HIV: a long-term relationship. Current Hiv/Aids Reports. 12: 33-40. PMID 25578055 DOI: 10.1007/s11904-014-0246-4  0.68
2015 Carnathan DG, Wetzel KS, Yu J, Lee ST, Johnson BA, Paiardini M, Yan J, Morrow MP, Sardesai NY, Weiner DB, Ertl HC, Silvestri G. Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. 112: 518-23. PMID 25550504 DOI: 10.1073/pnas.1407466112  0.68
2015 Yu H, Khalid M, Heigele A, Schmökel J, Usmani SM, van der Merwe J, Münch J, Silvestri G, Kirchhoff F. Lentiviral Nef proteins manipulate T cells in a subset-specific manner. Journal of Virology. 89: 1986-2001. PMID 25505066 DOI: 10.1128/JVI.03104-14  0.68
2015 Moniuszko M, Liyanage NP, Doster MN, Parks RW, Grubczak K, Lipinska D, McKinnon K, Brown C, Hirsch V, Vaccari M, Gordon S, Pegu P, Fenizia C, Flisiak R, Grzeszczuk A, ... ... Silvestri G, et al. Glucocorticoid treatment at moderate doses of SIVmac251-infected rhesus macaques decreases the frequency of circulating CD14+CD16++ monocytes but does not alter the tissue virus reservoir. Aids Research and Human Retroviruses. 31: 115-26. PMID 24432835 DOI: 10.1089/AID.2013.0220  0.68
2014 Rivera-Hernandez T, Carnathan DG, Moyle PM, Toth I, West NP, Young PR, Silvestri G, Walker MJ. The contribution of non-human primate models to the development of human vaccines. Discovery Medicine. 18: 313-22. PMID 25549702  0.68
2014 Micci L, Alvarez X, Iriele RI, Ortiz AM, Ryan ES, McGary CS, Deleage C, McAtee BB, He T, Apetrei C, Easley K, Pahwa S, Collman RG, Derdeyn CA, Davenport MP, ... ... Silvestri G, et al. CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells. Plos Pathogens. 10: e1004467. PMID 25356757 DOI: 10.1371/journal.ppat.1004467  0.68
2014 Mavigner M, Watkins B, Lawson B, Lee ST, Chahroudi A, Kean L, Silvestri G. Persistence of virus reservoirs in ART-treated SHIV-infected rhesus macaques after autologous hematopoietic stem cell transplant. Plos Pathogens. 10: e1004406. PMID 25254512 DOI: 10.1371/journal.ppat.1004406  0.68
2014 Klatt NR, Bosinger SE, Peck M, Richert-Spuhler LE, Heigele A, Gile JP, Patel N, Taaffe J, Julg B, Camerini D, Torti C, Martin JN, Deeks SG, Sinclair E, Hecht FM, ... ... Silvestri G, et al. Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals. Plos Pathogens. 10: e1004345. PMID 25167059 DOI: 10.1371/journal.ppat.1004345  0.68
2014 Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Münch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V. TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition. Developmental Cell. 30: 394-409. PMID 25127057 DOI: 10.1016/j.devcel.2014.06.013  0.68
2014 Sandler NG, Bosinger SE, Estes JD, Zhu RT, Tharp GK, Boritz E, Levin D, Wijeyesinghe S, Makamdop KN, del Prete GQ, Hill BJ, Timmer JK, Reiss E, Yarden G, Darko S, ... ... Silvestri G, et al. Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. Nature. 511: 601-5. PMID 25043006 DOI: 10.1038/nature13554  0.68
2014 Muyanja E, Ssemaganda A, Ngauv P, Cubas R, Perrin H, Srinivasan D, Canderan G, Lawson B, Kopycinski J, Graham AS, Rowe DK, Smith MJ, Isern S, Michael S, Silvestri G, et al. Immune activation alters cellular and humoral responses to yellow fever 17D vaccine. The Journal of Clinical Investigation. 124: 3147-58. PMID 24911151 DOI: 10.1172/JCI75429  0.68
2014 Cartwright EK, McGary CS, Cervasi B, Micci L, Lawson B, Elliott ST, Collman RG, Bosinger SE, Paiardini M, Vanderford TH, Chahroudi A, Silvestri G. Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections. Journal of Immunology (Baltimore, Md. : 1950). 192: 4666-73. PMID 24729621 DOI: 10.4049/jimmunol.1303193  0.68
2014 Chahroudi A, Cartwright E, Lee ST, Mavigner M, Carnathan DG, Lawson B, Carnathan PM, Hashempoor T, Murphy MK, Meeker T, Ehnert S, Souder C, Else JG, Cohen J, Collman RG, ... ... Silvestri G, et al. Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques. Plos Pathogens. 10: e1003958. PMID 24604066 DOI: 10.1371/journal.ppat.1003958  0.68
2014 McGary CS, Cervasi B, Chahroudi A, Micci L, Taaffe J, Meeker T, Silvestri G, Davenport MP, Paiardini M. Increased stability and limited proliferation of CD4+ central memory T cells differentiate nonprogressive simian immunodeficiency virus (SIV) infection of sooty mangabeys from progressive SIV infection of rhesus macaques. Journal of Virology. 88: 4533-42. PMID 24501416 DOI: 10.1128/JVI.03515-13  0.68
2014 Silvestri G, Ansari AA. Final Remarks: What Have We Learned from Natural Simian Immunodeficiency Virus Hosts that Can Help HIV-Infected Humans? Natural Hosts of Siv: Implication in Aids. 367-371. DOI: 10.1016/B978-0-12-404734-1.15001-6  0.68
2014 Ansari AA, Silvestri G. Comparative Studies of Natural and Non-natural Hosts of SIV-An Overview Natural Hosts of Siv: Implication in Aids. 1-18. DOI: 10.1016/B978-0-12-404734-1.00001-2  0.68
2014 AnsAri AA, Silvestri G. Natural Hosts of SIV: Implication in AIDS Natural Hosts of Siv: Implication in Aids. 1-385.  0.68
2013 Schmökel J, Li H, Shabir A, Yu H, Geyer M, Silvestri G, Sodora DL, Hahn BH, Kirchhoff F. Link between primate lentiviral coreceptor usage and Nef function. Cell Reports. 5: 997-1009. PMID 24268781 DOI: 10.1016/j.celrep.2013.10.028  0.68
2013 Francella N, Elliott ST, Yi Y, Gwyn SE, Ortiz AM, Li B, Silvestri G, Paiardini M, Derdeyn CA, Collman RG. Decreased plasticity of coreceptor use by CD4-independent SIV Envs that emerge in vivo. Retrovirology. 10: 133. PMID 24219995 DOI: 10.1186/1742-4690-10-133  0.68
2013 Bosinger SE, Johnson ZP, Folkner KA, Patel N, Hashempour T, Jochems SP, Del Rio Estrada PM, Paiardini M, Lin R, Vanderford TH, Hiscott J, Silvestri G. Intact type I Interferon production and IRF7 function in sooty mangabeys. Plos Pathogens. 9: e1003597. PMID 24009514 DOI: 10.1371/journal.ppat.1003597  0.68
2013 Letko M, Silvestri G, Hahn BH, Bibollet-Ruche F, Gokcumen O, Simon V, Ooms M. Vif proteins from diverse primate lentiviral lineages use the same binding site in APOBEC3G. Journal of Virology. 87: 11861-71. PMID 23986590 DOI: 10.1128/JVI.01944-13  0.68
2013 Chowdhury A, Silvestri G. Host-pathogen interaction in HIV infection. Current Opinion in Immunology. 25: 463-9. PMID 23890585 DOI: 10.1016/j.coi.2013.07.003  0.68
2013 Pallikkuth S, Micci L, Ende ZS, Iriele RI, Cervasi B, Lawson B, McGary CS, Rogers KA, Else JG, Silvestri G, Easley K, Estes JD, Villinger F, Pahwa S, Paiardini M. Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21. Plos Pathogens. 9: e1003471. PMID 23853592 DOI: 10.1371/journal.ppat.1003471  0.68
2013 Sundaravaradan V, Saleem R, Micci L, Gasper MA, Ortiz AM, Else J, Silvestri G, Paiardini M, Aitchison JD, Sodora DL. Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection. Plos Pathogens. 9: e1003441. PMID 23825945 DOI: 10.1371/journal.ppat.1003441  0.68
2013 Francella N, Gwyn SE, Yi Y, Li B, Xiao P, Elliott ST, Ortiz AM, Hoxie JA, Paiardini M, Silvestri G, Derdeyn CA, Collman RG. CD4+ T cells support production of simian immunodeficiency virus Env antibodies that enforce CD4-dependent entry and shape tropism in vivo. Journal of Virology. 87: 9719-32. PMID 23824793 DOI: 10.1128/JVI.01254-13  0.68
2013 Cervasi B, Carnathan DG, Sheehan KM, Micci L, Paiardini M, Kurupati R, Tuyishime S, Zhou XY, Else JG, Ratcliffe SJ, Ertl HC, Silvestri G. Immunological and virological analyses of rhesus macaques immunized with chimpanzee adenoviruses expressing the simian immunodeficiency virus Gag/Tat fusion protein and challenged intrarectally with repeated low doses of SIVmac. Journal of Virology. 87: 9420-30. PMID 23804645 DOI: 10.1128/JVI.01456-13  0.68
2013 Silvestri G. Embracing the complexity of HIV immunology. Immunological Reviews. 254: 5-9. PMID 23772611 DOI: 10.1111/imr.12081  0.68
2013 Evans DT, Silvestri G. Nonhuman primate models in AIDS research. Current Opinion in Hiv and Aids. 8: 255-61. PMID 23615116 DOI: 10.1097/COH.0b013e328361cee8  0.68
2013 Vaccari M, Keele BF, Bosinger SE, Doster MN, Ma ZM, Pollara J, Hryniewicz A, Ferrari G, Guan Y, Forthal DN, Venzon D, Fenizia C, Morgan T, Montefiori D, Lifson JD, ... ... Silvestri G, et al. Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure. Journal of Virology. 87: 3538-48. PMID 23325681 DOI: 10.1128/JVI.02863-12  0.68
2013 Kurupati R, Tuyishime S, Kossenkov AV, Sazanovich M, Haut LH, Lasaro MO, Ratcliffe SJ, Bosinger SE, Carnathan DG, Lewis M, Showe LC, Silvestri G, Ertl HC. Correlates of relative resistance against low-dose rectal simian immunodeficiency virus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaques. Journal of Leukocyte Biology. 93: 437-48. PMID 23271702 DOI: 10.1189/jlb.0612287  0.68
2013 Bosinger SE, Jochems SP, Folkner KA, Hayes TL, Klatt NR, Silvestri G. Transcriptional profiling of experimental CD8(+) lymphocyte depletion in rhesus macaques infected with simian immunodeficiency virus SIVmac239. Journal of Virology. 87: 433-43. PMID 23097439 DOI: 10.1128/JVI.01746-12  0.68
2013 Tabb B, Morcock DR, Trubey CM, Quiñones OA, Hao XP, Smedley J, Macallister R, Piatak M, Harris LD, Paiardini M, Silvestri G, Brenchley JM, Alvord WG, Lifson JD, Estes JD. Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection. The Journal of Infectious Diseases. 207: 880-92. PMID 23087435 DOI: 10.1093/infdis/jis643  0.68
2012 Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/j.chom.2012.09.008  0.68
2012 Brenchley JM, Vinton C, Tabb B, Hao XP, Connick E, Paiardini M, Lifson JD, Silvestri G, Estes JD. Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections. Blood. 120: 4172-81. PMID 22990012 DOI: 10.1182/blood-2012-06-437608  0.68
2012 Micci L, Cervasi B, Ende ZS, Iriele RI, Reyes-Aviles E, Vinton C, Else J, Silvestri G, Ansari AA, Villinger F, Pahwa S, Estes JD, Brenchley JM, Paiardini M. Paucity of IL-21-producing CD4(+) T cells is associated with Th17 cell depletion in SIV infection of rhesus macaques. Blood. 120: 3925-35. PMID 22990011 DOI: 10.1182/blood-2012-04-420240  0.68
2012 Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N, Chun TW, Churchill M, Di Mascio M, Katlama C, Lafeuillade A, Landay A, Lederman M, Lewin SR, ... ... Silvestri G, et al. Towards an HIV cure: a global scientific strategy. Nature Reviews. Immunology. 12: 607-14. PMID 22814509 DOI: 10.1038/nri3262  0.68
2012 Klatt NR, Estes JD, Sun X, Ortiz AM, Barber JS, Harris LD, Cervasi B, Yokomizo LK, Pan L, Vinton CL, Tabb B, Canary LA, Dang Q, Hirsch VM, Alter G, ... ... Silvestri G, et al. Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunology. 5: 646-57. PMID 22643849 DOI: 10.1038/mi.2012.38  0.68
2012 Zeng M, Paiardini M, Engram JC, Beilman GJ, Chipman JG, Schacker TW, Silvestri G, Haase AT. Critical role of CD4 T cells in maintaining lymphoid tissue structure for immune cell homeostasis and reconstitution. Blood. 120: 1856-67. PMID 22613799 DOI: 10.1182/blood-2012-03-418624  0.68
2012 Vanderford TH, Slichter C, Rogers KA, Lawson BO, Obaede R, Else J, Villinger F, Bosinger SE, Silvestri G. Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation. Blood. 119: 5750-7. PMID 22550346 DOI: 10.1182/blood-2012-02-411496  0.68
2012 Chahroudi A, Silvestri G. IRIS: the unfortunate rainbow of HIV. Blood. 119: 2971-2. PMID 22461468 DOI: 10.1182/blood-2012-01-403683  0.68
2012 Chahroudi A, Bosinger SE, Vanderford TH, Paiardini M, Silvestri G. Natural SIV hosts: showing AIDS the door. Science (New York, N.Y.). 335: 1188-93. PMID 22403383 DOI: 10.1126/science.1217550  0.68
2012 Klatt NR, Silvestri G. CD4+ T cells and HIV: A paradoxical Pas de Deux. Science Translational Medicine. 4: 123ps4. PMID 22378922 DOI: 10.1126/scitranslmed.3003862  0.68
2012 Klatt NR, Silvestri G, Hirsch V. Nonpathogenic simian immunodeficiency virus infections. Cold Spring Harbor Perspectives in Medicine. 2: a007153. PMID 22315718 DOI: 10.1101/cshperspect.a007153  0.68
2012 Souquiere S, Apetrei C, Chahroudi A, Pandrea I, Silvestri G, Roques P. Reply to "Control of Simian Immunodeficiency Virus SIVmnd-1 RNA Plasma Viremia after Coinfection or Superinfection with SIVmnd-1 in SIVmnd-2-Infected Mandrills and Vice Versa". Journal of Virology. 86: 2387-8. PMID 22282337 DOI: 10.1128/JVI.06953-11  0.68
2012 Puga I, Cols M, Barra CM, He B, Cassis L, Gentile M, Comerma L, Chorny A, Shan M, Xu W, Magri G, Knowles DM, Tam W, Chiu A, Bussel JB, ... ... Silvestri G, et al. B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nature Immunology. 13: 170-80. PMID 22197976 DOI: 10.1038/ni.2194  0.68
2012 Elliott ST, Riddick NE, Francella N, Paiardini M, Vanderford TH, Li B, Apetrei C, Sodora DL, Derdeyn CA, Silvestri G, Collman RG. Cloning and analysis of sooty mangabey alternative coreceptors that support simian immunodeficiency virus SIVsmm entry independently of CCR5. Journal of Virology. 86: 898-908. PMID 22090107 DOI: 10.1128/JVI.06415-11  0.68
2012 Taaffe JE, Bosinger SE, Del Prete GQ, Else JG, Ratcliffe S, Ward CD, Migone T, Paiardini M, Silvestri G. CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T cells in healthy, SIV-uninfected rhesus macaques. Journal of Medical Primatology. 41: 24-42. PMID 22077380 DOI: 10.1111/j.1600-0684.2011.00521.x  0.68
2012 Pancino G, Silvestri G, Fowke K. Models of Protection Against HIV/SIV Models of Protection Against Hiv/Siv 0.68
2011 Bosinger SE, Johnson ZP, Silvestri G. Primate genomes for biomedicine. Nature Biotechnology. 29: 983-4. PMID 22068533 DOI: 10.1038/nbt.2032  0.68
2011 Ortiz AM, Klatt NR, Li B, Yi Y, Tabb B, Hao XP, Sternberg L, Lawson B, Carnathan PM, Cramer EM, Engram JC, Little DM, Ryzhova E, Gonzalez-Scarano F, Paiardini M, ... ... Silvestri G, et al. Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques. The Journal of Clinical Investigation. 121: 4433-45. PMID 22005304 DOI: 10.1172/JCI46023  0.68
2011 Apetrei C, Sumpter B, Souquiere S, Chahroudi A, Makuwa M, Reed P, Ribeiro RM, Pandrea I, Roques P, Silvestri G. Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx). Journal of Virology. 85: 13077-87. PMID 21957286 DOI: 10.1128/JVI.05693-11  0.68
2011 Durudas A, Chen HL, Gasper MA, Sundaravaradan V, Milush JM, Silvestri G, Johnson W, Giavedoni LD, Sodora DL. Differential innate immune responses to low or high dose oral SIV challenge in Rhesus macaques. Current Hiv Research. 9: 276-88. PMID 21861823 DOI: 10.2174/157016211797635928  0.68
2011 Reed DL, Currier RW, Walton SF, Conrad M, Sullivan SA, Carlton JM, Read TD, Severini A, Tyler S, Eberle R, Johnson WE, Silvestri G, Clarke IN, Lagergård T, Lukehart SA, et al. The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organisms. Annals of the New York Academy of Sciences. 1230: 74-107. PMID 21824167 DOI: 10.1111/j.1749-6632.2011.06133.x  0.68
2011 Vinton C, Klatt NR, Harris LD, Briant JA, Sanders-Beer BE, Herbert R, Woodward R, Silvestri G, Pandrea I, Apetrei C, Hirsch VM, Brenchley JM. CD4-like immunological function by CD4- T cells in multiple natural hosts of simian immunodeficiency virus. Journal of Virology. 85: 8702-8. PMID 21715501 DOI: 10.1128/JVI.00332-11  0.68
2011 Paiardini M, Cervasi B, Reyes-Aviles E, Micci L, Ortiz AM, Chahroudi A, Vinton C, Gordon SN, Bosinger SE, Francella N, Hallberg PL, Cramer E, Schlub T, Chan ML, Riddick NE, ... ... Silvestri G, et al. Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression. Nature Medicine. 17: 830-6. PMID 21706028 DOI: 10.1038/nm.2395  0.68
2011 Kwa S, Kannanganat S, Nigam P, Siddiqui M, Shetty RD, Armstrong W, Ansari A, Bosinger SE, Silvestri G, Amara RR. Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques. Blood. 118: 2763-73. PMID 21693759 DOI: 10.1182/blood-2011-02-339515  0.68
2011 Vanderford TH, Bleckwehl C, Engram JC, Dunham RM, Klatt NR, Feinberg MB, Garber DA, Betts MR, Silvestri G. Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques. Plos Pathogens. 7: e1002048. PMID 21625590 DOI: 10.1371/journal.ppat.1002048  0.68
2011 Chahroudi A, Meeker T, Lawson B, Ratcliffe S, Else J, Silvestri G. Mother-to-infant transmission of simian immunodeficiency virus is rare in sooty mangabeys and is associated with low viremia. Journal of Virology. 85: 5757-63. PMID 21450815 DOI: 10.1128/JVI.02690-10  0.68
2011 Zeng M, Smith AJ, Wietgrefe SW, Southern PJ, Schacker TW, Reilly CS, Estes JD, Burton GF, Silvestri G, Lifson JD, Carlis JV, Haase AT. Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections. The Journal of Clinical Investigation. 121: 998-1008. PMID 21393864 DOI: 10.1172/JCI45157  0.68
2011 Milush JM, Mir KD, Sundaravaradan V, Gordon SN, Engram J, Cano CA, Reeves JD, Anton E, O'Neill E, Butler E, Hancock K, Cole KS, Brenchley JM, Else JG, Silvestri G, et al. Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells. The Journal of Clinical Investigation. 121: 1102-10. PMID 21317533 DOI: 10.1172/JCI44876  0.68
2011 Lasaro MO, Haut LH, Zhou X, Xiang Z, Zhou D, Li Y, Giles-Davis W, Li H, Engram JC, Dimenna LJ, Bian A, Sazanovich M, Parzych EM, Kurupati R, Small JC, ... ... Silvestri G, et al. Vaccine-induced T cells provide partial protection against high-dose rectal SIVmac239 challenge of rhesus macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 417-26. PMID 21081905 DOI: 10.1038/mt.2010.238  0.68
2010 Gordon SN, Cervasi B, Odorizzi P, Silverman R, Aberra F, Ginsberg G, Estes JD, Paiardini M, Frank I, Silvestri G. Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals. Journal of Immunology (Baltimore, Md. : 1950). 185: 5169-79. PMID 20889546 DOI: 10.4049/jimmunol.1001801  0.68
2010 Riddick NE, Hermann EA, Loftin LM, Elliott ST, Wey WC, Cervasi B, Taaffe J, Engram JC, Li B, Else JG, Li Y, Hahn BH, Derdeyn CA, Sodora DL, Apetrei C, ... ... Silvestri G, et al. A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo. Plos Pathogens. 6: e1001064. PMID 20865163 DOI: 10.1371/journal.ppat.1001064  0.68
2010 Estes JD, Harris LD, Klatt NR, Tabb B, Pittaluga S, Paiardini M, Barclay GR, Smedley J, Pung R, Oliveira KM, Hirsch VM, Silvestri G, Douek DC, Miller CJ, Haase AT, et al. Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections. Plos Pathogens. 6: e1001052. PMID 20808901 DOI: 10.1371/journal.ppat.1001052  0.68
2010 Chahroudi A, Silvestri G. Interleukin-7 in HIV pathogenesis and therapy. European Cytokine Network. 21: 202-7. PMID 20729180 DOI: 10.1684/ecn.2010.0205  0.68
2010 Brenchley JM, Silvestri G, Douek DC. Nonprogressive and progressive primate immunodeficiency lentivirus infections. Immunity. 32: 737-42. PMID 20620940 DOI: 10.1016/j.immuni.2010.06.004  0.68
2010 Chan ML, Petravic J, Ortiz AM, Engram J, Paiardini M, Cromer D, Silvestri G, Davenport MP. Limited CD4+ T cell proliferation leads to preservation of CD4+ T cell counts in SIV-infected sooty mangabeys. Proceedings. Biological Sciences / the Royal Society. 277: 3773-81. PMID 20591864 DOI: 10.1098/rspb.2010.0972  0.68
2010 Sodora DL, Silvestri G. HIV, mucosal tissues, and T helper 17 cells: where we come from, where we are, and where we go from here. Current Opinion in Hiv and Aids. 5: 111-3. PMID 20543586 DOI: 10.1097/COH.0b013e328335c18f  0.68
2010 Harris LD, Tabb B, Sodora DL, Paiardini M, Klatt NR, Douek DC, Silvestri G, Müller-Trutwin M, Vasile-Pandrea I, Apetrei C, Hirsch V, Lifson J, Brenchley JM, Estes JD. Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques. Journal of Virology. 84: 7886-91. PMID 20484518 DOI: 10.1128/JVI.02612-09  0.68
2010 Engram JC, Cervasi B, Borghans JA, Klatt NR, Gordon SN, Chahroudi A, Else JG, Mittler RS, Sodora DL, de Boer RJ, Brenchley JM, Silvestri G, Paiardini M. Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates. Blood. 116: 748-58. PMID 20484087 DOI: 10.1182/blood-2010-01-263814  0.68
2010 Taaffe J, Chahroudi A, Engram J, Sumpter B, Meeker T, Ratcliffe S, Paiardini M, Else J, Silvestri G. A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation. Journal of Virology. 84: 5476-84. PMID 20335252 DOI: 10.1128/JVI.00039-10  0.68
2010 Klatt NR, Shudo E, Ortiz AM, Engram JC, Paiardini M, Lawson B, Miller MD, Else J, Pandrea I, Estes JD, Apetrei C, Schmitz JE, Ribeiro RM, Perelson AS, Silvestri G. CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells. Plos Pathogens. 6: e1000747. PMID 20126441 DOI: 10.1371/journal.ppat.1000747  0.68
2010 Silvestri G. Current Opinion in HIV and AIDS: Editorial introduction Current Opinion in Hiv and Aids. 5. DOI: 10.1097/COH.0b013e3283373418  0.68
2009 Bosinger SE, Li Q, Gordon SN, Klatt NR, Duan L, Xu L, Francella N, Sidahmed A, Smith AJ, Cramer EM, Zeng M, Masopust D, Carlis JV, Ran L, Vanderford TH, ... ... Silvestri G, et al. Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. The Journal of Clinical Investigation. 119: 3556-72. PMID 19959874 DOI: 10.1172/JCI40115  0.68
2009 Jacquelin B, Mayau V, Targat B, Liovat AS, Kunkel D, Petitjean G, Dillies MA, Roques P, Butor C, Silvestri G, Giavedoni LD, Lebon P, Barré-Sinoussi F, Benecke A, Müller-Trutwin MC. Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response Journal of Clinical Investigation. 119: 3544-3555. PMID 19959873 DOI: 10.1172/JCI40093  0.68
2009 Shedlock DJ, Silvestri G, Weiner DB. Monkeying around with HIV vaccines: using rhesus macaques to define 'gatekeepers' for clinical trials. Nature Reviews. Immunology. 9: 717-28. PMID 19859066 DOI: 10.1038/nri2636  0.68
2009 Sodora DL, Allan JS, Apetrei C, Brenchley JM, Douek DC, Else JG, Estes JD, Hahn BH, Hirsch VM, Kaur A, Kirchhoff F, Muller-Trutwin M, Pandrea I, Schmitz JE, Silvestri G. Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nature Medicine. 15: 861-5. PMID 19661993 DOI: 10.1038/nm.2013  0.68
2009 Paiardini M, Pandrea I, Apetrei C, Silvestri G. Lessons learned from the natural hosts of HIV-related viruses. Annual Review of Medicine. 60: 485-95. PMID 19630581 DOI: 10.1146/  0.68
2009 Keele BF, Jones JH, Terio KA, Estes JD, Rudicell RS, Wilson ML, Li Y, Learn GH, Beasley TM, Schumacher-Stankey J, Wroblewski E, Mosser A, Raphael J, Kamenya S, Lonsdorf EV, ... ... Silvestri G, et al. Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz. Nature. 460: 515-9. PMID 19626114 DOI: 10.1038/nature08200  0.68
2009 Ortiz AM, Silvestri G. Immunopathogenesis of AIDS. Current Infectious Disease Reports. 11: 239-45. PMID 19366567 DOI: 10.1007/s11908-009-0035-1  0.68
2009 Silvestri G. Immunity in natural SIV infections Journal of Internal Medicine. 265: 97-109. PMID 19093963 DOI: 10.1111/j.1365-2796.2008.02049.x  0.68
2009 Paiardini M, Hoffman J, Cervasi B, Ortiz AM, Stroud F, Silvestri G, Wilson ME. T-cell phenotypic and functional changes associated with social subordination and gene polymorphisms in the serotonin reuptake transporter in female rhesus monkeys. Brain, Behavior, and Immunity. 23: 286-93. PMID 18992804 DOI: 10.1016/j.bbi.2008.10.006  0.68
2008 Silvestri G. AIDS pathogenesis: A tale of two monkeys Journal of Medical Primatology. 37: 6-12. PMID 19187426 DOI: 10.1111/j.1600-0684.2008.00328.x  0.68
2008 Meier A, Fisher A, Sidhu HK, Chang JJ, Wen TF, Streeck H, Alter G, Silvestri G, Altfeld M. Rapid loss of dendritic cell and monocyte responses to TLR ligands following venipuncture. Journal of Immunological Methods. 339: 132-40. PMID 18848564 DOI: 10.1016/j.jim.2008.09.007  0.68
2008 Kirchhoff F, Silvestri G. Is Nef the elusive cause of HIV-associated hematopoietic dysfunction? The Journal of Clinical Investigation. 118: 1622-5. PMID 18431512 DOI: 10.1172/JCI35487  0.68
2008 Sodora DL, Silvestri G. Immune activation and AIDS pathogenesis Aids. 22: 439-446. PMID 18301056 DOI: 10.1097/QAD.0b013e3282f2dbe7  0.68
2005 Silvestri G. Naturally SIV-infected sooty mangabeys: Are we closer to understanding why they do not develop AIDS? Journal of Medical Primatology. 34: 243-252. PMID 16128919 DOI: 10.1111/j.1600-0684.2005.00122.x  0.68
2005 Derdeyn CA, Silvestri G. Viral and host factors in the pathogenesis of HIV infection Current Opinion in Immunology. 17: 366-373. PMID 15955686 DOI: 10.1016/j.coi.2005.06.001  0.68
2003 Silvestri G, Feinberg MB. Turnover of lymphocytes and conceptual paradigms in HIV infection Journal of Clinical Investigation. 112: 821-824. PMID 12975464 DOI: 10.1172/JCI19799  0.68
2002 Feinberg MB, Silvestri G. TS cells and immune tolerance induction: A regulatory renaissance? Nature Immunology. 3: 215-217. PMID 11875459 DOI: 10.1038/ni0302-215  0.68
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