Paul R. Carlier, Ph.D.

Affiliations: 
1988-1991 Chemistry Polaroid, Sankt-Peterburg, Saint Petersburg, Russia 
 1991-2000 Chemistry Hong Kong Univ. of Sci. & Technology 
 2000- Chemistry Virginia Polytechnic and State University, United States 
Area:
Stereoselective synthesis, medicinal chemistry
Website:
http://www.carliergroup.chem.vt.edu
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Parents

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K. Barry Sharpless grad student 1983-1988 MIT

Children

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Polo C. Lam grad student 2004 Virginia Tech
Ella C. Clement grad student 2005 Virginia Tech
Stephanie L. MacQuarrie grad student 2005 Virginia Tech
Joseph C. DeGuzman grad student 2006 Virginia Tech
Danny C. Hsu grad student 2007 Virginia Tech
Yiqun Zhang grad student 2007 Virginia Tech
Henry J. Harmon grad student 2008 Virginia Tech
Larry D. Williams grad student 2008 Virginia Tech
Nipa Deora grad student 2010 Virginia Tech
Christopher J. Monceaux grad student 2010 Virginia Tech
Neeraj Patwardhan grad student 2012 Virginia Tech
Astha Verma grad student 2014 Virginia Tech
Eugene Camerino grad student 2015 Virginia Tech
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Publications

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Deora N, Carlier PR. (2019) A computational study of regioselectivity in aluminum hydride ring-opening of cis- and trans-4-t-butyl and 3-methylcyclohexene oxides. Organic & Biomolecular Chemistry
Mutunga JM, Ma M, Chen QH, et al. (2019) Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates. International Journal of Environmental Research and Public Health. 16
Taylor-Wells J, Gross AD, Jiang S, et al. (2018) Toxicity, mode of action, and synergist potential of flonicamid against mosquitoes. Pesticide Biochemistry and Physiology. 151: 3-9
Carlier PR, Chen QH, Verma A, et al. (2018) Select β- and γ-branched 1-alkylpyrazol-4-yl methylcarbamates exhibit high selectivity for inhibition of versus human acetylcholinesterase. Pesticide Biochemistry and Physiology. 151: 32-39
Chen H, Wu X, Gu X, et al. (2018) Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice. Frontiers in Cellular Neuroscience. 12: 396
Clements JS, Islam R, Sun B, et al. (2017) N'-mono- and N, N'-diacyl derivatives of benzyl and arylhydrazines as contact insecticides against adult Anopheles gambiae. Pesticide Biochemistry and Physiology. 143: 33-38
Ghavami M, Merino EF, Yao Z, et al. (2017) Biological studies and target-engagement of the 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD)-targeting antimalarial agent (1R,3S)-MMV008138 and analogs. Acs Infectious Diseases
Han Q, Wong DM, Robinson H, et al. (2017) Crystal structure of acetylcholinesterase catalytic subunits of the malaria vector Anopheles gambiae. Insect Science
Carlier PR, Bloomquist JR, Totrov M, et al. (2017) Discovery of Species-selective and Resistance-breaking Anticholinesterase Insecticides for the Malaria Mosquito. Current Medicinal Chemistry
Mutunga JM, Chen QH, Wong DM, et al. (2016) Bivalent Carbamates as Novel Control Agents of the Malaria Mosquito, Anopheles gambiae. Chimia. 70: 704-708
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