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K. Barry Sharpless

Massachusetts Institute of Technology, Cambridge, MA, United States 
 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Click chemistry
"K. Barry Sharpless"
The Nobel Prize in Chemistry 2001 was divided, one half jointly to William S. Knowles and Ryoji Noyori "for their work on chirally catalysed hydrogenation reactions" and the other half to K. Barry Sharpless "for his work on chirally catalysed oxidation reactions".

Mean distance: 6.5


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Thomas A. Spencer research assistant 1963 Dartmouth
Eugene van Tamelen grad student 1968 Stanford
 (Studies of the mechanism of action of 2,3-oxidosqualenelanosterol cyclase featuring enzymic cyclization of modified squalene oxides.)
James Paddock Collman post-doc 1968 Stanford
Konrad Bloch post-doc 1969 Harvard


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John-Stephen A. Taylor research assistant 1972-1976 MIT
Gregory C. Fu research assistant 1985 MIT
Jiajia Dong research assistant 2009-2015 Scripps Institute
Qinheng Zheng grad student 2014- Scripps Institute
Gencheng Li grad student 2016- Scripps Institute
M.G. Finn grad student 1986 MIT
Janice Klunder grad student 1987 MIT
Paul R. Carlier grad student 1983-1988 MIT
Remi Chauvin grad student 1988-1990 Scripps Institute
Jay P. Chiang grad student 2000 Scripps Institute
David S. Nirschl grad student 2000 Scripps Institute
Allen A. Thomas grad student 2000 Scripps Institute
Zachary P. Demko grad student 2002 Scripps Institute
Antonella Converso grad student 2003 Scripps Institute
Steven M. Silverman grad student 2002-2004 Scripps Institute
Timothy R. Chan grad student 2005 Scripps Institute
Peng Wu grad student 2005 Scripps Institute
Alina K. Feldman grad student 2006 Scripps Institute
David Berrisford post-doc MIT
benoit colasson post-doc TSRI
Christophe Coperet post-doc Scripps Institute
S. Bruce King post-doc Scripps Institute
Stefan Loren post-doc Scripps Institute
Koichiro Oshima post-doc MIT
Boris Schmidt post-doc (Microtree)
Jan-Erling Bäckvall post-doc 1976-1977 MIT
Lanny S. Liebeskind post-doc 1978 Stanford
Eric N. Jacobsen post-doc 1986-1988 MIT
Carsten Bolm post-doc 1987-1988
István E. Markó post-doc 1987-1988 MIT and Harvard
Matthias Beller post-doc 1990 MIT
Davit Zargarian post-doc 1992 Scripps Institute
Hartmuth C. Kolb post-doc 1993 Scripps Institute
Pher Andersson post-doc 1992-1993 Scripps Institute
Per-Ola Norrby post-doc 1992-1993 Scripps Institute
Patrick J. Walsh post-doc 1991-1994 Scripps Institute
Dominic V. McGrath post-doc 1992-1994 Scripps Institute
Michael S. VanNieuwenhze post-doc 1992-1994 Scripps Institute
Alexander S.S. Dömling post-doc 1994-1995 Scripps Institute
Andrei K. Yudin post-doc 1998 Scripps Institute
Erland P. Stevens post-doc 1997-1998 Scripps Institute
Valery V. Fokin post-doc 1998-2001 Scripps Institute
Roman Manetsch post-doc 2002-2005 Scripps Institute
Carlos A. Valdez post-doc 2006-2008 Scripps Institute
Jason E. Hein post-doc 2005-2009 The Scripps Research Institute, California, USA
Suhua Li post-doc 2014-2017 Scripps Institute
Hua-Li Qin research scientist Scripps Institute


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Flavio Grynszpan collaborator 2000-2002 Scripps Institute
BETA: Related publications


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Liu F, Wang H, Li S, et al. (2019) Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4) Derived Connective Hubs For Bioconjugation to DNA and Proteins. Angewandte Chemie (International Ed. in English)
Hong S, Shi Y, Wu NC, et al. (2019) Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification. Nature Communications. 10: 1799
Kovarik Z, Hrvat NM, Kalisiak J, et al. (2019) Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase. Toxicology and Applied Pharmacology
Smedley CJ, Zheng Q, Gao B, et al. (2019) Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. Angewandte Chemie (International Ed. in English)
Kovarik Z, Kalisiak J, Hrvat NM, et al. (2018) Reversal of tabun toxicity, enabled by a triazole annulated oxime library-reactivators of acetylcholinesterase. Chemistry (Weinheim An Der Bergstrasse, Germany)
Sit R, Kovarik Z, Macek-Hrvat N, et al. (2018) Pharmacology, pharmacokinetics and tissue disposition of zwitterionic hydoxyiminoacetamido alkylamines as reactivating antidotes for organophosphate exposure. The Journal of Pharmacology and Experimental Therapeutics
Gahtory D, Sen R, Pujari S, et al. (2018) Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms. Chemistry (Weinheim An Der Bergstrasse, Germany)
Liu Z, Li J, Li S, et al. (2018) SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization. Journal of the American Chemical Society
Sharpless KB, Gao B, Li S, et al. (2018) SuFEx Chemistry of Thionyl Tetrafluoride (SOF4) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides and Sulfonimidates. Angewandte Chemie (International Ed. in English)
Guo T, Meng G, Zhan X, et al. (2017) A New Portal to SuFEx Click Chemistry: a Stable Fluorosulfuryl Imidazolium Salt Emerging as an "F-SO2+" Donor of Unprecedented Reactivity, Selectivity, and Scope. Angewandte Chemie (International Ed. in English)
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