Chitra R. Edwankar
Affiliations: | 2011 | University of Wisconsin-Milwaukee, Milwaukee, WI |
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"Chitra Edwankar"Mean distance: 8.39 | S | N | B | C | P |
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Sign in to add mentorJames M. Cook | grad student | 2011 | UW-Milwaukee | |
(Part I: The first regio- and atropdiastereoselective total synthesis of the dimeric indole alkaloid (+)-dispegatrine, as well as the first total synthesis of the sarpagine alkaloids (+)-spegatrine, lochvinerine, (+)-lochneram and an improved total synthes) |
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Publications
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Edwankar RV, Edwankar CR, Deschamps JR, et al. (2014) General strategy for synthesis of C-19 methyl-substituted sarpagine/macroline/ajmaline indole alkaloids including total synthesis of 19(S),20(R)-dihydroperaksine, 19(S),20(R)-dihydroperaksine-17-al, and peraksine. The Journal of Organic Chemistry. 79: 10030-48 |
Edwankar CR, Edwankar RV, Namjoshi OA, et al. (2013) Stereospecific approach to the synthesis of ring-A oxygenated sarpagine indole alkaloids. Total synthesis of the dimeric indole alkaloid P-(+)-dispegatrine and six other monomeric indole alkaloids. The Journal of Organic Chemistry. 78: 6471-87 |
Edwankar CR, Edwankar RV, Deschamps JR, et al. (2012) Nature-inspired stereospecific total synthesis of P-(+)-dispegatrine and four other monomeric sarpagine indole alkaloids. Angewandte Chemie (International Ed. in English). 51: 11762-5 |
Edwankar RV, Edwankar CR, Namjoshi OA, et al. (2012) Brønsted acid mediated cyclization of enaminones. Rapid and efficient access to the tetracyclic framework of the Strychnos alkaloids. Journal of Natural Products. 75: 181-8 |
Edwankar RV, Edwankar CR, Deschamps J, et al. (2011) Regiospecific, enantiospecific total synthesis of C-19 methyl substituted sarpagine alkaloids dihydroperaksine-17-al and dihydroperaksine. Organic Letters. 13: 5216-9 |
Edwankar CR, Edwankar RV, Namjoshi OA, et al. (2009) Recent progress in the total synthesis of indole alkaloids. Current Opinion in Drug Discovery & Development. 12: 752-71 |
Rivas FM, Stables JP, Murphree L, et al. (2009) Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models. Journal of Medicinal Chemistry. 52: 1795-8 |
Edwankar CR, Edwankar RV, Rallapalli S, et al. (2008) General approach to the total synthesis of macroline-related sarpagine and ajmaline alkaloids Natural Product Communications. 3: 1839-1870 |