Chandrabali Bhattacharya, Ph.D.

Affiliations: 
2009-2015 Chemistry Arizona State University, Tempe, AZ, United States 
 2015-2017 Chemistry and Chemical Engineering California Institute of Technology, Pasadena, CA 
 2017- Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Natural products, Bleomycin, Glycochemistry and Glycobiology
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Parents

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Sidney M. Hecht grad student 2009-2015 Arizona State
 (Small Molecule Probes for Studying Cellular Receptors and Enzymes.)
Daniel G. Anderson post-doc 2017- MIT
Robert S. Langer post-doc 2017- MIT
Linda C. Hsieh-Wilson post-doc 2015-2017 Caltech
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Publications

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Daskalova SM, Bhattacharya C, Dedkova LM, et al. (2016) Probing the Flexibility of the Catalytic Nucleophile in the Lyase Catalytic Pocket of Human DNA Polymerase β with Unnatural Lysine Analogues. Biochemistry
Talukder P, Chen S, Roy B, et al. (2015) Cyanotryptophans as Novel Fluorescent Probes for Studying Protein Conformational Changes and DNA-Protein Interaction. Biochemistry
Yu Z, Paul R, Bhattacharya C, et al. (2015) Structural features facilitating tumor cell targeting and internalization by bleomycin and its disaccharide. Biochemistry. 54: 3100-9
Yu X, Talukder P, Bhattacharya C, et al. (2014) Probing of CD4 binding pocket of HIV-1 gp120 glycoprotein using unnatural phenylalanine analogues. Bioorganic & Medicinal Chemistry Letters. 24: 5699-703
Madathil MM, Bhattacharya C, Yu Z, et al. (2014) Modified bleomycin disaccharides exhibiting improved tumor cell targeting. Biochemistry. 53: 6800-10
Schroeder BR, Ghare MI, Bhattacharya C, et al. (2014) The disaccharide moiety of bleomycin facilitates uptake by cancer cells. Journal of the American Chemical Society. 136: 13641-56
Bhattacharya C, Yu Z, Rishel MJ, et al. (2014) The carbamoylmannose moiety of bleomycin mediates selective tumor cell targeting. Biochemistry. 53: 3264-6
Roy R, De Sarkar N, Ghose S, et al. (2014) Genetic variations at microRNA and processing genes and risk of oral cancer. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 35: 3409-14
Chen S, Fahmi NE, Bhattacharya C, et al. (2013) Fluorescent biphenyl derivatives of phenylalanine suitable for protein modification. Biochemistry. 52: 8580-9
Chen S, Fahmi NE, Wang L, et al. (2013) Detection of dihydrofolate reductase conformational change by FRET using two fluorescent amino acids. Journal of the American Chemical Society. 135: 12924-7
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