☰ Chemistry Tree

Hoang V. Le, Ph.D.

Affiliations:	2008	Chemistry	University of California, Berkeley, Berkeley, CA, United States
	2013	Chemistry and Chemical Biology	Cornell University, Ithaca, NY, United States
	2016	Chemistry	Northwestern University, Evanston, IL
	2016-	BioMolecular Sciences	University of Missisippi School of Pharmacy

Area:

Medicinal Chemistry and Enzymology

Website:

http://hlelab.com

Google:

Mean distance: 8.17

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Parents

Bruce Ganem	grad student	2013	Cornell
(Progress in the development of multicomponent reactions.)
Richard B. Silverman	post-doc	2016	Northwestern

Children

Md Imdadul H Khan

grad student

University of Mississippi

Collaborators

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Publications

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Lykins J, Moschitto MJ, Zhou Y, et al. (2023) From O/GABA-AT, GABA, and T-263 Mutant to Conception of . Iscience. 27: 108477
Kdimy A, Kim SJ, Ali Z, et al. (2023) Isolation of Two Plasticizers, Bis(2-Ethylhexyl) Terephthalate and Bis(2-Ethylhexyl) Phthalate, from Capparis spinosa L. Leaves. Chemistry & Biodiversity. e202300903
Akins NS, Salahuddin MF, Pandey P, et al. (2023) Alleviation of Cocaine Withdrawal and Pertinent Interactions between Salvinorin-Based Antagonists and Kappa Opioid Receptor. Acs Chemical Neuroscience
Khan MIH, Mahdi F, Penfornis P, et al. (2022) Synthesis and biological evaluation of tert-butyl ester and ethyl ester prodrugs of L-γ-methyleneglutamic acid amides for cancer. Bioorganic & Medicinal Chemistry. 78: 117137
Khan MIH, Sawyer BJ, Akins NS, et al. (2022) A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse. European Journal of Medicinal Chemistry. 243: 114785
Hossain MI, Khan MIH, Kim SJ, et al. (2022) Synthesis of 3,4,5-trisubstituted isoxazoles in water via a [3 + 2]-cycloaddition of nitrile oxides and 1,3-diketones, β-ketoesters, or β-ketoamides. Beilstein Journal of Organic Chemistry. 18: 446-458
Xu J, Chen F, Wang S, et al. (2020) Kappa opioid receptors internalization is protective against oxygen-glucose deprivation through β-arrestin activation and Akt-mediated signaling pathway. Neurochemistry International. 104748
Juncosa JI, Takaya K, Le HV, et al. (2018) Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction. Journal of the American Chemical Society
Mascarenhas R, Le HV, Clevenger KD, et al. (2017) Correction to Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover. Biochemistry
Mascarenhas R, Le HV, Clevenger KD, et al. (2017) Selective Targeting by a Mechanism-based Inactivator against PLP-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover. Biochemistry

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