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Tian Chen, Ph.D.

Affiliations: 
2011 Chemistry Northwestern University, Evanston, IL 
Area:
Organic, Synthetic, Bio-Organic, Medicinal Chemistry, Chemical Biology
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"Tian Chen"
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Richard B. Silverman grad student 2011 Northwestern
 (Arylsulfanyl Pyrazolones Block Mutant SOD1 Aggregation and have Potential Application for the Treatment of Amyotrophic Lateral Sclerosis.)

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Publications

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Yang H, Bai Y, Chen T, et al. (2016) Synthesis of Hierarchical (BiO)2CO3 Nanosheets Microspheres toward Efficient Photocatalystic Reduction of CO2 into CO Physica E: Low-Dimensional Systems and Nanostructures. 78: 100-104
Zhu Y, Li X, Chen J, et al. (2015) The pentacyclic triterpene Lupeol switches M1 macrophages to M2 and ameliorates experimental inflammatory bowel disease. International Immunopharmacology. 30: 74-84
Zhu YP, Xu X, Su H, et al. (2015) Ultrafine Metal Phosphide Nanocrystals in situ Decorated on Highly Porous Heteroatom-Doped Carbons for Active Electrocatalytic Hydrogen Evolution. Acs Applied Materials & Interfaces
Su S, Duan J, Chen T, et al. (2015) Corrigendum: Frankincense and myrrh suppress inflammation via regulation of the metabolic profiling and the MAPK signaling pathway. Scientific Reports. 5: 15597
Zhang Y, Benmohamed R, Huang H, et al. (2013) Arylazanylpyrazolone derivatives as inhibitors of mutant superoxide dismutase 1 dependent protein aggregation for the treatment of amyotrophic lateral sclerosis. Journal of Medicinal Chemistry. 56: 2665-75
Chen T, Benmohamed R, Kim J, et al. (2012) ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: potential application for the treatment of amyotrophic lateral sclerosis. Journal of Medicinal Chemistry. 55: 515-27
Chen T, Benmohamed R, Arvanites AC, et al. (2011) Arylsulfanyl pyrazolones block mutant SOD1-G93A aggregation. Potential application for the treatment of amyotrophic lateral sclerosis. Bioorganic & Medicinal Chemistry. 19: 613-22
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