Stephen E. Leonard, Ph.D.
Affiliations: | 2011 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
Chemical biologyGoogle:
"Stephen Leonard"Mean distance: 8.57
Parents
Sign in to add mentor| Anna K. Mapp | grad student | 2011 | University of Michigan | |
| (Developing Tools to Investigate Protein Sulfenylation in Living Cells.) | ||||
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Publications
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| Kong L, Barber T, Aldinger J, et al. (2021) ROS generation is involved in titanium dioxide nanoparticle-induced AP-1 activation through p38 MAPK and ERK pathways in JB6 cells. Environmental Toxicology. 37: 237-244 |
| Crowther GJ, Hillesland HK, Keyloun KR, et al. (2016) Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds. Plos One. 11: e0149996 |
| Register AC, Leonard SE, Maly DJ. (2014) SH2-catalytic domain linker heterogeneity influences allosteric coupling across the SFK family. Biochemistry. 53: 6910-23 |
| Leonard SE, Register AC, Krishnamurty R, et al. (2014) Divergent modulation of Src-family kinase regulatory interactions with ATP-competitive inhibitors. Acs Chemical Biology. 9: 1894-905 |
| Vidadala RS, Ojo KK, Johnson SM, et al. (2014) Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes. European Journal of Medicinal Chemistry. 74: 562-73 |
| Krishnamurty R, Brigham JL, Leonard SE, et al. (2013) Active site profiling reveals coupling between domains in SRC-family kinases. Nature Chemical Biology. 9: 43-50 |
| Barrett TJ, Pattison DI, Leonard SE, et al. (2012) Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates. Free Radical Biology & Medicine. 52: 1075-85 |
| Paulsen CE, Truong TH, Garcia FJ, et al. (2012) Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity. Nature Chemical Biology. 8: 57-64 |
| Leonard SE, Garcia FJ, Goodsell DS, et al. (2011) Redox-based probes for protein tyrosine phosphatases. Angewandte Chemie (International Ed. in English). 50: 4423-7 |
| Leonard SE, Carroll KS. (2011) Chemical 'omics' approaches for understanding protein cysteine oxidation in biology. Current Opinion in Chemical Biology. 15: 88-102 |